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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs142857449
log Bayes Factor = 0.552909
Chromosome 7   position 85,048,380  (GRCh37) Explore rs142857449 on Ensembl!
Variant rs142857449 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20 Angina pectoris
0.667 0.333 0.000
I20.0 Unstable angina
0.667 0.333 0.000
I20-I25 Ischaemic heart diseases
0.664 0.336 0.000
Chapter IX Diseases of the circulatory system
0.652 0.348 0.000
I25 Chronic ischaemic heart disease
0.641 0.359 0.000
I60-I69 Cerebrovascular diseases
0.634 0.366 0.000
I25.2 Old myocardial infarction
0.611 0.389 0.000
I30-I52 Other forms of heart disease
0.609 0.391 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.594 0.406 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.588 0.412 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.587 0.413 0.000
I25.1 Atherosclerotic heart disease
0.587 0.413 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.586 0.414 0.000
I31 Other diseases of pericardium
0.582 0.418 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.577 0.423 0.000
I31.3 Pericardial effusion (noninflammatory)
0.572 0.428 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.569 0.431 0.000
I65.2 Occlusion and stenosis of carotid artery
0.566 0.434 0.000
O60-O75 Complications of labour and delivery
0.561 0.439 0.000
I20.9 Angina pectoris, unspecified
0.560 0.440 0.000
I51 Complications and ill-defined descriptions of heart disease
0.546 0.454 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.546 0.454 0.000
I20.1 Angina pectoris with documented spasm
0.544 0.456 0.000
I45 Other conduction disorders
0.543 0.457 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.540 0.460 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.522 0.478 0.000
# Top node
0.522 0.478 0.000
I38 Endocarditis, valve unspecified
0.518 0.482 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.517 0.483 0.000
O36 Maternal care for other known or suspected foetal problems
0.513 0.487 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.506 0.494 0.000
I05-I09 Chronic rheumatic heart diseases
0.506 0.494 0.000
I69 Sequelae of cerebrovascular disease
0.500 0.500 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.493 0.507 0.000
O42 Premature rupture of membranes
0.489 0.511 0.000
I21 Acute myocardial infarction
0.489 0.511 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.486 0.514 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.480 0.520 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.478 0.522 0.000
I72 Other aneurysm
0.478 0.522 0.000
I23 Certain current complications following acute myocardial infarction
0.476 0.523 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.476 0.524 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.475 0.525 0.000
I63 Cerebral infarction
0.472 0.528 0.000
M20-M25 Other joint disorders
0.468 0.532 0.000
I00-I02 Acute rheumatic fever
0.467 0.533 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.467 0.533 0.000
Chapter XIV Diseases of the genitourinary system
0.467 0.533 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.462 0.538 0.000
I51.8 Other ill-defined heart diseases
0.460 0.540 0.000
I25.6 Silent myocardial ischaemia
0.460 0.540 0.000
I25.4 Coronary artery aneurysm
0.460 0.540 0.000
I25.3 Aneurysm of heart
0.460 0.540 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.460 0.540 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.454 0.545 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.454 0.545 0.000
M23 Internal derangement of knee
0.451 0.549 0.000
M15-M19 Arthrosis
0.448 0.552 0.000
O40 Polyhydramnios
0.448 0.552 0.000
I22 Subsequent myocardial infarction
0.448 0.552 0.000
I45.1 Other and unspecified right bundle-branch block
0.447 0.553 0.000
O47 False labour
0.447 0.553 0.000
I20.8 Other forms of angina pectoris
0.446 0.554 0.000
O34.1 Maternal care for tumour of corpus uteri
0.446 0.554 0.000
Chapter VI Diseases of the nervous system
0.445 0.555 0.000
I67 Other cerebrovascular diseases
0.442 0.558 0.000
I51.0 Cardiac septal defect, acquired
0.442 0.558 0.000
I45.9 Conduction disorder, unspecified
0.440 0.560 0.000
O63 Long labour
0.440 0.560 0.000
O72 Postpartum haemorrhage
0.438 0.561 0.000
I70 Atherosclerosis
0.438 0.562 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.438 0.562 0.000
O30 Multiple gestation
0.437 0.563 0.000
I52 Other heart disorders in diseases classified elsewhere
0.437 0.563 0.000
I48 Atrial fibrillation and flutter
0.437 0.563 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.437 0.563 0.000
I41 Myocarditis in diseases classified elsewhere
0.437 0.563 0.000
I40 Acute myocarditis
0.437 0.563 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.437 0.563 0.000
I37 Pulmonary valve disorders
0.437 0.563 0.000
I36 Nonrheumatic tricuspid valve disorders
0.437 0.563 0.000
I32 Pericarditis in diseases classified elsewhere
0.437 0.563 0.000
I30 Acute pericarditis
0.436 0.563 0.000
Q60-Q64 Congenital malformations of the urinary system
0.435 0.565 0.000
M23.3 Other meniscus derangements
0.435 0.565 0.000
I33 Acute and subacute endocarditis
0.434 0.566 0.000
I72.4 Aneurysm of artery of lower extremity
0.433 0.567 0.000
O61 Failed induction of labour
0.433 0.567 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.432 0.568 0.000
I60 Subarachnoid haemorrhage
0.432 0.568 0.000
O00-O08 Pregnancy with abortive outcome
0.432 0.568 0.000
O36.8 Maternal care for other specified foetal problems
0.432 0.568 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.432 0.568 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.431 0.569 0.000
I34 Nonrheumatic mitral valve disorders
0.428 0.572 0.000
I62 Other nontraumatic intracranial haemorrhage
0.427 0.573 0.000
O62 Abnormalities of forces of labour
0.426 0.574 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.426 0.574 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.426 0.574 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.426 0.574 0.000
I65.1 Occlusion and stenosis of basilar artery
0.426 0.574 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.426 0.574 0.000
N40-N51 Diseases of male genital organs
0.426 0.574 0.000
M17 Gonarthrosis [arthrosis of knee]
0.425 0.575 0.000
O45 Premature separation of placenta [abruptio placentae]
0.421 0.579 0.000
O44 Placenta praevia
0.421 0.579 0.000
O43 Placental disorders
0.421 0.579 0.000
O41 Other disorders of amniotic fluid and membranes
0.421 0.579 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.421 0.579 0.000
O33 Maternal care for known or suspected disproportion
0.421 0.579 0.000
O31 Complications specific to multiple gestation
0.421 0.579 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.421 0.579 0.000
I51.7 Cardiomegaly
0.421 0.579 0.000
O85-O92 Complications predominantly related to the puerperium
0.420 0.580 0.000
Chapter VIII Diseases of the ear and mastoid process
0.420 0.580 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.420 0.580 0.000
I25.5 Ischaemic cardiomyopathy
0.420 0.580 0.000
O66 Other obstructed labour
0.419 0.581 0.000
I49 Other cardiac arrhythmias
0.418 0.582 0.000
I45.5 Other specified heart block
0.418 0.582 0.000
I31.8 Other specified diseases of pericardium
0.417 0.583 0.000
I31.2 Haemopericardium, not elsewhere classified
0.417 0.583 0.000
I31.1 Chronic constrictive pericarditis
0.417 0.583 0.000
I31.0 Chronic adhesive pericarditis
0.417 0.583 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.414 0.586 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.414 0.586 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.414 0.586 0.000
O34.6 Maternal care for abnormality of vagina
0.414 0.586 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.414 0.586 0.000
O34.4 Maternal care for other abnormalities of cervix
0.414 0.586 0.000
O34.3 Maternal care for cervical incompetence
0.414 0.586 0.000
O34.0 Maternal care for congenital malformation of uterus
0.414 0.586 0.000
O36.9 Maternal care for foetal problem, unspecified
0.412 0.588 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.410 0.590 0.000
I42 Cardiomyopathy
0.410 0.590 0.000
N17-N19 Renal failure
0.407 0.593 0.000
I46 Cardiac arrest
0.407 0.593 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.406 0.593 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.406 0.594 0.000
O75.0 Maternal distress during labour and delivery
0.406 0.594 0.000
N48 Other disorders of penis
0.404 0.596 0.000
Q61 Cystic kidney disease
0.403 0.597 0.000
I45.6 Preexcitation syndrome
0.403 0.597 0.000
O74 Complications of anaesthesia during labour and delivery
0.402 0.597 0.000
O71 Other obstetric trauma
0.402 0.597 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.402 0.597 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.402 0.597 0.000
O60 Preterm delivery
0.402 0.597 0.000
M17.0 Primary gonarthrosis, bilateral
0.403 0.597 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.399 0.601 0.000
O32.1 Maternal care for breech presentation
0.399 0.601 0.000
M23.4 Loose body in knee
0.398 0.601 0.000
M25 Other joint disorders, not elsewhere classified
0.398 0.602 0.000
N60-N64 Disorders of breast
0.396 0.604 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.396 0.604 0.000
I51.9 Heart disease, unspecified
0.394 0.606 0.000
O73 Retained placenta and membranes, without haemorrhage
0.394 0.606 0.000
I07 Rheumatic tricuspid valve diseases
0.393 0.607 0.000
N10-N16 Renal tubulo-interstitial diseases
0.393 0.607 0.000
O70 Perineal laceration during delivery
0.392 0.608 0.000
M05-M14 Inflammatory polyarthropathies
0.392 0.608 0.000
I77 Other disorders of arteries and arterioles
0.391 0.608 0.000
I51.6 Cardiovascular disease, unspecified
0.391 0.609 0.000
I51.5 Myocardial degeneration
0.391 0.609 0.000
I51.4 Myocarditis, unspecified
0.391 0.609 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.391 0.609 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.391 0.609 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.391 0.609 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.391 0.609 0.000
O97 Death from sequelae of direct obstetric causes
0.391 0.609 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.391 0.609 0.000
O95 Obstetric death of unspecified cause
0.391 0.609 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.391 0.609 0.000
I61 Intracerebral haemorrhage
0.391 0.609 0.000
Chapter I Certain infectious and parasitic diseases
0.391 0.609 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.390 0.610 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.390 0.610 0.000
I45.8 Other specified conduction disorders
0.389 0.611 0.000
I45.4 Nonspecific intraventricular block
0.389 0.611 0.000
I45.3 Trifascicular block
0.389 0.611 0.000
I45.2 Bifascicular block
0.389 0.611 0.000
I45.0 Right fascicular block
0.389 0.611 0.000
I69.3 Sequelae of cerebral infarction
0.388 0.612 0.000
O24 Diabetes mellitus in pregnancy
0.386 0.614 0.000
O36.6 Maternal care for excessive foetal growth
0.386 0.614 0.000
O36.5 Maternal care for poor foetal growth
0.385 0.615 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.384 0.616 0.000
M17.1 Other primary gonarthrosis
0.384 0.616 0.000
I63.9 Cerebral infarction, unspecified
0.384 0.616 0.000
I21.9 Acute myocardial infarction, unspecified
0.382 0.618 0.000
O75.8 Other specified complications of labour and delivery
0.381 0.619 0.000
M31 Other necrotising vasculopathies
0.381 0.619 0.000
M24 Other specific joint derangements
0.381 0.619 0.000
I71 Aortic aneurysm and dissection
0.380 0.620 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.380 0.620 0.000
H90-H95 Other disorders of ear
0.380 0.620 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.380 0.620 0.000
I50 Heart failure
0.377 0.623 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.376 0.624 0.000
N60 Benign mammary dysplasia
0.376 0.624 0.000
M65-M68 Disorders of synovium and tendon
0.375 0.625 0.000
O63.0 Prolonged first stage (of labour)
0.375 0.625 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.374 0.626 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.374 0.626 0.000
Chapter XXII Codes for special purposes
0.373 0.626 0.000
I05 Rheumatic mitral valve diseases
0.372 0.627 0.000
N40 Hyperplasia of prostate
0.373 0.627 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.372 0.628 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.371 0.629 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.371 0.629 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.371 0.629 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.371 0.629 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.371 0.629 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.371 0.629 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.371 0.629 0.000
N48.1 Balanoposthitis
0.369 0.631 0.000
M21 Other acquired deformities of limbs
0.369 0.631 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.368 0.632 0.000
O36.4 Maternal care for intra-uterine death
0.368 0.632 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.368 0.632 0.000
O36.2 Maternal care for hydrops foetalis
0.368 0.632 0.000
O36.1 Maternal care for other isoimmunisation
0.368 0.632 0.000
M91-M94 Chondropathies
0.368 0.632 0.000
N18 Chronic renal failure
0.367 0.633 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.367 0.633 0.000
I74 Arterial embolism and thrombosis
0.366 0.634 0.000
M22 Disorders of patella
0.365 0.635 0.000
M80-M85 Disorders of bone density and structure
0.365 0.635 0.000
O75.9 Complication of labour and delivery, unspecified
0.363 0.637 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.363 0.637 0.000
O75.4 Other complications of obstetric surgery and procedures
0.363 0.637 0.000
O75.3 Other infection during labour
0.363 0.637 0.000
O75.1 Shock during or following labour and delivery
0.363 0.637 0.000
I08 Multiple valve diseases
0.363 0.637 0.000
I09 Other rheumatic heart diseases
0.363 0.637 0.000
I06 Rheumatic aortic valve diseases
0.363 0.637 0.000
I70.0 Atherosclerosis of aorta
0.361 0.639 0.000
M23.49 Loose body in knee-Unspec lig/men
0.361 0.639 0.000
B25-B34 Other viral diseases
0.360 0.640 0.000
G30-G32 Other degenerative diseases of the nervous system
0.359 0.641 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.359 0.641 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.358 0.641 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.358 0.641 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.358 0.641 0.000
Q61.2 Polycystic kidney, adult type
0.358 0.642 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.357 0.643 0.000
M19 Other arthrosis
0.357 0.643 0.000
G90-G99 Other disorders of the nervous system
0.356 0.644 0.000
Q50-Q56 Congenital malformations of genital organs
0.355 0.644 0.000
G40-G47 Episodic and paroxysmal disorders
0.355 0.645 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.355 0.645 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.354 0.646 0.000
O69.8 Labour and delivery complicated by other cord complications
0.354 0.646 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.354 0.646 0.000
O69.4 Labour and delivery complicated by vasa praevia
0.354 0.646 0.000
O69.3 Labour and delivery complicated by short cord
0.354 0.646 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.354 0.646 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.353 0.647 0.000
I67.1 Cerebral aneurysm, nonruptured
0.352 0.647 0.000
O21 Excessive vomiting in pregnancy
0.352 0.648 0.000
N18.3 Chronic kidney disease, stage 3
0.352 0.648 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.351 0.649 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.351 0.649 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.351 0.649 0.000
O72.1 Other immediate postpartum haemorrhage
0.351 0.649 0.000
M60-M63 Disorders of muscles
0.348 0.652 0.000
M00-M03 Infectious arthropathies
0.348 0.652 0.000
I27 Other pulmonary heart diseases
0.347 0.653 0.000
O26.9 Pregnancy-related condition, unspecified
0.347 0.653 0.000
I78 Diseases of capillaries
0.345 0.655 0.000
I95 Hypotension
0.345 0.655 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.344 0.655 0.000
Q80-Q89 Other congenital malformations
0.344 0.655 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.344 0.655 0.000
Q35-Q37 Cleft lip and cleft palate
0.344 0.655 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.344 0.655 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.344 0.655 0.000
Q00-Q07 Congenital malformations of the nervous system
0.344 0.655 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.344 0.656 0.000
O02 Other abnormal products of conception
0.344 0.656 0.000
Q61.3 Polycystic kidney, unspecified
0.344 0.656 0.000
I99 Other and unspecified disorders of circulatory system
0.343 0.657 0.000
N72 Inflammatory disease of cervix uteri
0.343 0.657 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.343 0.657 0.000
O32.8 Maternal care for other malpresentation of foetus
0.343 0.657 0.000
O32.6 Maternal care for compound presentation
0.343 0.657 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.343 0.657 0.000
O32.4 Maternal care for high head at term
0.343 0.657 0.000
O32.3 Maternal care for face, brow and chin presentation
0.343 0.657 0.000
O32.2 Maternal care for transverse and oblique lie
0.343 0.657 0.000
O32.0 Maternal care for unstable lie
0.343 0.657 0.000
I72.9 Aneurysm of unspecified site
0.342 0.657 0.000
I72.8 Aneurysm of other specified arteries
0.342 0.657 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.342 0.657 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.342 0.657 0.000
I72.3 Aneurysm of iliac artery
0.342 0.657 0.000
I72.2 Aneurysm of renal artery
0.342 0.657 0.000
I72.1 Aneurysm of artery of upper extremity
0.342 0.657 0.000
I72.0 Aneurysm of carotid artery
0.342 0.657 0.000
I49.3 Ventricular premature depolarisation
0.342 0.658 0.000
I23.8 Other current complications following acute myocardial infarction
0.342 0.658 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.342 0.658 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.342 0.658 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.342 0.658 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.342 0.658 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.342 0.658 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.342 0.658 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.342 0.658 0.000
I42.2 Other hypertrophic cardiomyopathy
0.342 0.658 0.000
O29 Complications of anaesthesia during pregnancy
0.341 0.659 0.000
O28 Abnormal findings on antenatal screening of mother
0.341 0.659 0.000
O23 Infections of genito-urinary tract in pregnancy
0.341 0.659 0.000
O22 Venous complications in pregnancy
0.341 0.659 0.000
O25 Malnutrition in pregnancy
0.341 0.659 0.000
O61.0 Failed medical induction of labour
0.340 0.660 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.340 0.660 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.340 0.660 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.339 0.661 0.000
G20-G26 Extrapyramidal and movement disorders
0.339 0.661 0.000
N48.8 Other specified disorders of penis
0.339 0.661 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.338 0.662 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.338 0.662 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.338 0.662 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.338 0.662 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.338 0.662 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.338 0.662 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.338 0.662 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.338 0.662 0.000
B34 Viral infection of unspecified site
0.338 0.662 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.337 0.663 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.336 0.664 0.000
M34 Systemic sclerosis
0.336 0.664 0.000
M33 Dermatopolymyositis
0.336 0.664 0.000
M32 Systemic lupus erythematosus
0.336 0.664 0.000
M30 Polyarteritis nodosa and related conditions
0.336 0.664 0.000
I49.9 Cardiac arrhythmia, unspecified
0.336 0.664 0.000
I02 Rheumatic chorea
0.335 0.665 0.000
I01 Rheumatic fever with heart involvement
0.335 0.665 0.000
I00 Rheumatic fever without mention of heart involvement
0.335 0.665 0.000
I28 Other diseases of pulmonary vessels
0.335 0.665 0.000
N60.2 Fibroadenosis of breast
0.334 0.665 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.334 0.666 0.000
H91 Other hearing loss
0.334 0.666 0.000
M25.4 Effusion of joint
0.333 0.667 0.000
I34.1 Mitral (valve) prolapse
0.333 0.667 0.000
N48.6 Balanitis xerotica obliterans
0.332 0.668 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.331 0.669 0.000
M86-M90 Other osteopathies
0.331 0.669 0.000
O30.0 Twin pregnancy
0.329 0.670 0.000
I67.8 Other specified cerebrovascular diseases
0.329 0.670 0.000
O62.2 Other uterine inertia
0.329 0.671 0.000
O47.0 False labour before 37 completed weeks of gestation
0.329 0.671 0.000
O48 Prolonged pregnancy
0.329 0.671 0.000
I46.9 Cardiac arrest, unspecified
0.328 0.671 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.328 0.672 0.000
M10 Gout
0.328 0.672 0.000
N19 Unspecified renal failure
0.327 0.673 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.326 0.674 0.000
I66.8 Occlusion and stenosis of other cerebral artery
0.326 0.674 0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.326 0.674 0.000
I66.3 Occlusion and stenosis of cerebellar arteries
0.326 0.674 0.000
I66.2 Occlusion and stenosis of posterior cerebral artery
0.326 0.674 0.000
I66.1 Occlusion and stenosis of anterior cerebral artery
0.326 0.674 0.000
I66.0 Occlusion and stenosis of middle cerebral artery
0.326 0.674 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.326 0.674 0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.326 0.674 0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.326 0.674 0.000
I68.0 Cerebral amyloid angiopathy
0.326 0.674 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.325 0.674 0.000
M25.0 Haemarthrosis
0.326 0.674 0.000
I44 Atrioventricular and left bundle-branch block
0.325 0.675 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.325 0.675 0.000
H90 Conductive and sensorineural hearing loss
0.324 0.676 0.000
N00-N08 Glomerular diseases
0.324 0.676 0.000
M23.9 Internal derangement of knee, unspecified
0.323 0.677 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.323 0.677 0.000
M23.5 Chronic instability of knee
0.323 0.677 0.000
M23.1 Discoid meniscus (congenital)
0.323 0.677 0.000
M23.0 Cystic meniscus
0.323 0.677 0.000
B35-B49 Mycoses
0.323 0.677 0.000
O70.9 Perineal laceration during delivery, unspecified
0.322 0.678 0.000
B34.9 Viral infection, unspecified
0.322 0.678 0.000
M15 Polyarthrosis
0.321 0.678 0.000
I26 Pulmonary embolism
0.322 0.678 0.000
N45 Orchitis and epididymitis
0.321 0.679 0.000
I22.8 Subsequent myocardial infarction of other sites
0.321 0.679 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.321 0.679 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.321 0.679 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.321 0.679 0.000
N13 Obstructive and reflux uropathy
0.321 0.679 0.000
N43 Hydrocele and spermatocele
0.321 0.679 0.000
M40-M43 Deforming dorsopathies
0.321 0.679 0.000
H60-H62 Diseases of external ear
0.320 0.680 0.000
O47.9 False labour, unspecified
0.320 0.680 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.320 0.680 0.000
O70.2 Third degree perineal laceration during delivery
0.319 0.680 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.319 0.680 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.319 0.681 0.000
M31.6 Other giant cell arteritis
0.318 0.682 0.000
I50.9 Heart failure, unspecified
0.317 0.683 0.000
I63.8 Other cerebral infarction
0.317 0.683 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.317 0.683 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.317 0.683 0.000
I67.5 Moyamoya disease
0.317 0.683 0.000
I67.4 Hypertensive encephalopathy
0.317 0.683 0.000
I67.3 Progressive vascular leukoencephalopathy
0.317 0.683 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.317 0.683 0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent
0.317 0.683 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.317 0.683 0.000
N70 Salpingitis and oophoritis
0.317 0.683 0.000
O63.9 Long labour, unspecified
0.315 0.685 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.315 0.685 0.000
N99-N99 Other disorders of the genitourinary system
0.315 0.685 0.000
M65 Synovitis and tenosynovitis
0.315 0.685 0.000
O72.3 Postpartum coagulation defects
0.314 0.685 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.314 0.685 0.000
O72.0 Third-stage haemorrhage
0.314 0.685 0.000
I70.9 Generalised and unspecified atherosclerosis
0.314 0.685 0.000
I70.8 Atherosclerosis of other arteries
0.314 0.685 0.000
I70.1 Atherosclerosis of renal artery
0.314 0.685 0.000
O30.9 Multiple gestation, unspecified
0.314 0.686 0.000
O30.8 Other multiple gestation
0.314 0.686 0.000
O30.2 Quadruplet pregnancy
0.314 0.686 0.000
O30.1 Triplet pregnancy
0.314 0.686 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.313 0.687 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.313 0.687 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.313 0.687 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.313 0.687 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.313 0.687 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.313 0.687 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.313 0.687 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.313 0.687 0.000
I37.9 Pulmonary valve disorder, unspecified
0.313 0.687 0.000
I37.8 Other pulmonary valve disorders
0.313 0.687 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.313 0.687 0.000
I37.1 Pulmonary valve insufficiency
0.313 0.687 0.000
I37.0 Pulmonary valve stenosis
0.313 0.687 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.313 0.687 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.313 0.687 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.313 0.687 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.313 0.687 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.313 0.687 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.313 0.687 0.000
I40.9 Acute myocarditis, unspecified
0.313 0.687 0.000
I40.8 Other acute myocarditis
0.313 0.687 0.000
I40.1 Isolated myocarditis
0.313 0.687 0.000
I40.0 Infective myocarditis
0.313 0.687 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.313 0.687 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.313 0.687 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.313 0.687 0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.313 0.687 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.313 0.687 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.313 0.687 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.313 0.687 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.313 0.687 0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.313 0.687 0.000
I48.4 Atypical atrial flutter
0.313 0.687 0.000
I48.3 Typical atrial flutter
0.313 0.687 0.000
I48.2 Chronic atrial fibrillation
0.313 0.687 0.000
I48.1 Persistent atrial fibrillation
0.313 0.687 0.000
I48.0 Paroxysmal atrial fibrillation
0.313 0.687 0.000
I52.8 Other heart disorders in other diseases classified elsewhere
0.313 0.687 0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.313 0.687 0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.313 0.687 0.000
I30.8 Other forms of acute pericarditis
0.313 0.687 0.000
I30.1 Infective pericarditis
0.313 0.687 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.313 0.687 0.000
M07 Psoriatic and enteropathic arthropathies
0.313 0.687 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.313 0.687 0.000
I07.1 Tricuspid insufficiency
0.313 0.687 0.000
I21.4 Acute subendocardial myocardial infarction
0.313 0.687 0.000
I30.9 Acute pericarditis, unspecified
0.313 0.687 0.000
I47 Paroxysmal tachycardia
0.313 0.687 0.000
Q64 Other congenital malformations of urinary system
0.312 0.688 0.000
Q63 Other congenital malformations of kidney
0.312 0.688 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.312 0.688 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.312 0.688 0.000
N25-N29 Other disorders of kidney and ureter
0.312 0.688 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.312 0.688 0.000
M23.37 Other meniscus derangements-Capsular lig
0.312 0.688 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.312 0.688 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.312 0.688 0.000
I33.9 Acute endocarditis, unspecified
0.311 0.688 0.000
G40 Epilepsy
0.311 0.689 0.000
O61.9 Failed induction of labour, unspecified
0.310 0.690 0.000
O61.8 Other failed induction of labour
0.310 0.690 0.000
O61.1 Failed instrumental induction of labour
0.310 0.690 0.000
G70-G73 Diseases of myoneural junction and muscle
0.310 0.690 0.000
I60.8 Other subarachnoid haemorrhage
0.310 0.690 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.310 0.690 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.310 0.690 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.310 0.690 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.310 0.690 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.310 0.690 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.310 0.690 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.310 0.690 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.310 0.690 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.310 0.690 0.000
O07 Failed attempted abortion
0.310 0.690 0.000
O06 Unspecified abortion
0.310 0.690 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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