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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs143050142
log Bayes Factor = 1.0623
Chromosome 6   position 167,329,144  (GRCh37) Explore rs143050142 on Ensembl!
Variant rs143050142 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.911 0.089 0.000
Chapter XIV Diseases of the genitourinary system
0.909 0.091 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.902 0.098 0.000
N30-N39 Other diseases of urinary system
0.896 0.104 0.000
Chapter VIII Diseases of the ear and mastoid process
0.875 0.125 0.000
O60-O75 Complications of labour and delivery
0.862 0.138 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.852 0.148 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.827 0.173 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.821 0.179 0.000
H65-H75 Diseases of middle ear and mastoid
0.818 0.182 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.817 0.183 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.798 0.202 0.000
N32 Other disorders of bladder
0.794 0.206 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.788 0.212 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.784 0.216 0.000
H80-H83 Diseases of inner ear
0.783 0.217 0.000
N30 Cystitis
0.783 0.217 0.000
D50-D53 Nutritional anaemias
0.774 0.226 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.771 0.229 0.000
N40-N51 Diseases of male genital organs
0.770 0.230 0.000
Chapter X Diseases of the respiratory system
0.767 0.233 0.000
Chapter II Neoplasms
0.764 0.236 0.000
D50 Iron deficiency anaemia
0.744 0.256 0.000
E00-E07 Disorders of thyroid gland
0.744 0.256 0.000
N35 Urethral stricture
0.740 0.260 0.000
H72 Perforation of tympanic membrane
0.735 0.265 0.000
N60-N64 Disorders of breast
0.732 0.268 0.000
N25-N29 Other disorders of kidney and ureter
0.724 0.276 0.000
O00-O08 Pregnancy with abortive outcome
0.721 0.279 0.000
Chapter I Certain infectious and parasitic diseases
0.715 0.285 0.000
S00-S09 Injuries to the head
0.714 0.286 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.711 0.289 0.000
N36 Other disorders of urethra
0.709 0.291 0.000
Chapter XXI Factors influencing health status and contact with health services
0.704 0.296 0.000
O48 Prolonged pregnancy
0.703 0.297 0.000
N10-N16 Renal tubulo-interstitial diseases
0.697 0.303 0.000
N32.8 Other specified disorders of bladder
0.693 0.307 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.684 0.316 0.000
D10-D36 Benign neoplasms
0.683 0.317 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.681 0.319 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.679 0.321 0.000
D50.8 Other iron deficiency anaemias
0.677 0.323 0.000
N39 Other disorders of urinary system
0.673 0.327 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.673 0.327 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.672 0.327 0.000
H83 Other diseases of inner ear
0.672 0.328 0.000
O80-O84 Delivery
0.670 0.330 0.000
D50.9 Iron deficiency anaemia, unspecified
0.668 0.332 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.668 0.332 0.000
E03 Other hypothyroidism
0.658 0.342 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.657 0.343 0.000
S80-S89 Injuries to the knee and lower leg
0.657 0.343 0.000
H71 Cholesteatoma of middle ear
0.656 0.344 0.000
N30.9 Cystitis, unspecified
0.655 0.345 0.000
S20-S29 Injuries to the thorax
0.655 0.345 0.000
O42 Premature rupture of membranes
0.654 0.345 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.654 0.346 0.000
Chapter XXII Codes for special purposes
0.653 0.346 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.653 0.346 0.000
H81 Disorders of vestibular function
0.653 0.347 0.000
N99-N99 Other disorders of the genitourinary system
0.652 0.348 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.650 0.350 0.000
H65 Nonsuppurative otitis media
0.649 0.351 0.000
O85-O92 Complications predominantly related to the puerperium
0.647 0.353 0.000
N37 Urethral disorders in diseases classified elsewhere
0.643 0.357 0.000
N34 Urethritis and urethral syndrome
0.643 0.357 0.000
N33 Bladder disorders in diseases classified elsewhere
0.643 0.357 0.000
S50-S59 Injuries to the elbow and forearm
0.642 0.358 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.641 0.359 0.000
N40 Hyperplasia of prostate
0.640 0.360 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.639 0.361 0.000
S90-S99 Injuries to the ankle and foot
0.637 0.362 0.000
N73 Other female pelvic inflammatory diseases
0.637 0.362 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.636 0.364 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.635 0.365 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.634 0.366 0.000
N43 Hydrocele and spermatocele
0.632 0.368 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.630 0.369 0.000
N50 Other disorders of male genital organs
0.630 0.370 0.000
N32.3 Diverticulum of bladder
0.628 0.372 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.627 0.373 0.000
N35.9 Urethral stricture, unspecified
0.627 0.373 0.000
H60-H62 Diseases of external ear
0.627 0.373 0.000
C34 Malignant neoplasm of bronchus and lung
0.626 0.374 0.000
S40-S49 Injuries to the shoulder and upper arm
0.622 0.377 0.000
O72 Postpartum haemorrhage
0.621 0.379 0.000
E04 Other non-toxic goitre
0.620 0.380 0.000
D00-D09 In situ neoplasms
0.619 0.381 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.618 0.382 0.000
O74 Complications of anaesthesia during labour and delivery
0.618 0.382 0.000
O73 Retained placenta and membranes, without haemorrhage
0.618 0.382 0.000
O71 Other obstetric trauma
0.618 0.382 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.618 0.382 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.618 0.382 0.000
O66 Other obstructed labour
0.618 0.382 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.618 0.382 0.000
O62 Abnormalities of forces of labour
0.618 0.382 0.000
O61 Failed induction of labour
0.618 0.382 0.000
O60 Preterm delivery
0.618 0.382 0.000
J20-J22 Other acute lower respiratory infections
0.618 0.382 0.000
O36 Maternal care for other known or suspected foetal problems
0.616 0.384 0.000
N20-N23 Urolithiasis
0.614 0.386 0.000
N00-N08 Glomerular diseases
0.612 0.388 0.000
N72 Inflammatory disease of cervix uteri
0.612 0.388 0.000
N30.2 Other chronic cystitis
0.611 0.389 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.611 0.389 0.000
T79-T79 Certain early complications of trauma
0.611 0.389 0.000
T66-T78 Other and unspecified effects of external causes
0.611 0.389 0.000
T33-T35 Frostbite
0.611 0.389 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.611 0.389 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.611 0.389 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.611 0.389 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.611 0.389 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.611 0.389 0.000
T00-T07 Injuries involving multiple body regions
0.611 0.389 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.611 0.389 0.000
S10-S19 Injuries to the neck
0.611 0.389 0.000
N70 Salpingitis and oophoritis
0.610 0.390 0.000
S00 Superficial injury of head
0.609 0.391 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.609 0.391 0.000
N81 Female genital prolapse
0.607 0.393 0.000
O63 Long labour
0.604 0.396 0.000
O70 Perineal laceration during delivery
0.604 0.396 0.000
H72.0 Central perforation of tympanic membrane
0.604 0.396 0.000
Z37 Outcome of delivery
0.602 0.398 0.000
S60-S69 Injuries to the wrist and hand
0.601 0.399 0.000
N30.8 Other cystitis
0.600 0.400 0.000
H66 Suppurative and unspecified otitis media
0.600 0.400 0.000
E03.9 Hypothyroidism, unspecified
0.596 0.404 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.594 0.406 0.000
E65-E68 Obesity and other hyperalimentation
0.593 0.407 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.593 0.407 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.593 0.407 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.593 0.407 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.593 0.407 0.000
H83.0 Labyrinthitis
0.592 0.408 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.591 0.409 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.591 0.409 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.591 0.409 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.588 0.411 0.000
O45 Premature separation of placenta [abruptio placentae]
0.588 0.411 0.000
O44 Placenta praevia
0.588 0.411 0.000
O43 Placental disorders
0.588 0.411 0.000
O41 Other disorders of amniotic fluid and membranes
0.588 0.411 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.588 0.411 0.000
O33 Maternal care for known or suspected disproportion
0.588 0.411 0.000
O31 Complications specific to multiple gestation
0.588 0.411 0.000
O30 Multiple gestation
0.588 0.411 0.000
O40 Polyhydramnios
0.588 0.411 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.587 0.413 0.000
H74 Other disorders of middle ear and mastoid
0.587 0.413 0.000
H73 Other disorders of tympanic membrane
0.587 0.413 0.000
H70 Mastoiditis and related conditions
0.587 0.413 0.000
H69 Other disorders of Eustachian tube
0.587 0.413 0.000
H68 Eustachian salpingitis and obstruction
0.587 0.413 0.000
H67 Otitis media in diseases classified elsewhere
0.587 0.413 0.000
N32.0 Bladder-neck obstruction
0.586 0.414 0.000
D80-D89 Certain disorders involving the immune mechanism
0.586 0.414 0.000
D55-D59 Haemolytic anaemias
0.586 0.414 0.000
J30-J39 Other diseases of upper respiratory tract
0.586 0.414 0.000
D17 Benign lipomatous neoplasm
0.585 0.415 0.000
E50-E64 Other nutritional deficiencies
0.584 0.416 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.584 0.416 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.580 0.420 0.000
J00-J06 Acute upper respiratory infections
0.578 0.422 0.000
S70-S79 Injuries to the hip and thigh
0.577 0.422 0.000
Chapter XX External causes of morbidity and mortality
0.577 0.423 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.576 0.424 0.000
N36.8 Other specified disorders of urethra
0.575 0.425 0.000
N39.9 Disorder of urinary system, unspecified
0.573 0.427 0.000
N60 Benign mammary dysplasia
0.573 0.427 0.000
J95-J99 Other diseases of the respiratory system
0.572 0.428 0.000
B95-B98 Bacterial, viral and other infectious agents
0.571 0.429 0.000
Chapter V Mental and behavioural disorders
0.571 0.429 0.000
J60-J70 Lung diseases due to external agents
0.570 0.430 0.000
N32.4 Rupture of bladder, nontraumatic
0.569 0.431 0.000
N32.2 Vesical fistula, not elsewhere classified
0.569 0.431 0.000
N32.1 Vesicointestinal fistula
0.569 0.431 0.000
O47 False labour
0.566 0.434 0.000
Z37.0 Single live birth
0.566 0.434 0.000
E40-E46 Malnutrition
0.565 0.435 0.000
E20-E35 Disorders of other endocrine glands
0.565 0.435 0.000
O04 Medical abortion
0.563 0.437 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.562 0.438 0.000
N76 Other inflammation of vagina and vulva
0.562 0.438 0.000
N75 Diseases of Bartholin's gland
0.562 0.438 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.562 0.438 0.000
N71 Inflammatory disease of uterus, except cervix
0.562 0.438 0.000
H80 Otosclerosis
0.562 0.438 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.562 0.438 0.000
N30.4 Irradiation cystitis
0.561 0.439 0.000
N30.3 Trigonitis
0.561 0.439 0.000
N30.1 Interstitial cystitis (chronic)
0.561 0.439 0.000
N30.0 Acute cystitis
0.561 0.439 0.000
O16 Unspecified maternal hypertension
0.560 0.440 0.000
H90-H95 Other disorders of ear
0.559 0.441 0.000
M70-M79 Other soft tissue disorders
0.558 0.442 0.000
N64 Other disorders of breast
0.556 0.443 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.556 0.444 0.000
D53 Other nutritional anaemias
0.555 0.445 0.000
D52 Folate deficiency anaemia
0.555 0.445 0.000
D51 Vitamin B12 deficiency anaemia
0.554 0.446 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.552 0.447 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.552 0.447 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.552 0.447 0.000
J40-J47 Chronic lower respiratory diseases
0.552 0.448 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.552 0.448 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.552 0.448 0.000
N42 Other disorders of prostate
0.552 0.448 0.000
N41 Inflammatory diseases of prostate
0.552 0.448 0.000
N46 Male infertility
0.552 0.448 0.000
N44 Torsion of testis
0.552 0.448 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.551 0.448 0.000
N32.9 Bladder disorder, unspecified
0.551 0.449 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.550 0.450 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.550 0.450 0.000
O02 Other abnormal products of conception
0.549 0.450 0.000
D60-D64 Aplastic and other anaemias
0.549 0.450 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.549 0.451 0.000
C50-C50 Malignant neoplasm of breast
0.548 0.452 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.548 0.452 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.548 0.452 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.548 0.452 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.548 0.452 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.548 0.452 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.548 0.452 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.548 0.452 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.547 0.453 0.000
N48 Other disorders of penis
0.546 0.454 0.000
A30-A49 Other bacterial diseases
0.545 0.455 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.543 0.456 0.000
D22 Melanocytic naevi
0.542 0.458 0.000
N81.1 Cystocele
0.542 0.458 0.000
N13 Obstructive and reflux uropathy
0.541 0.459 0.000
N17-N19 Renal failure
0.541 0.459 0.000
C34.3 Lower lobe, bronchus or lung
0.540 0.460 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.540 0.460 0.000
N81.6 Rectocele
0.538 0.462 0.000
N63 Unspecified lump in breast
0.537 0.462 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.535 0.464 0.000
S00.8 Superficial injury of other parts of head
0.535 0.465 0.000
J09-J18 Influenza and pneumonia
0.534 0.466 0.000
D50.1 Sideropenic dysphagia
0.533 0.466 0.000
E07 Other disorders of thyroid
0.533 0.467 0.000
E06 Thyroiditis
0.533 0.467 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.533 0.467 0.000
E00 Congenital iodine-deficiency syndrome
0.533 0.467 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.533 0.467 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.533 0.467 0.000
D27 Benign neoplasm of ovary
0.533 0.467 0.000
N43.3 Hydrocele, unspecified
0.533 0.467 0.000
N73.6 Female pelvic peritoneal adhesions
0.532 0.468 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.532 0.468 0.000
Z50 Care involving use of rehabilitation procedures
0.531 0.469 0.000
N35.8 Other urethral stricture
0.530 0.470 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.530 0.470 0.000
N35.0 Posttraumatic urethral stricture
0.530 0.470 0.000
E70-E90 Metabolic disorders
0.530 0.470 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.529 0.471 0.000
B25-B34 Other viral diseases
0.529 0.471 0.000
D18 Haemangioma and lymphangioma, any site
0.528 0.472 0.000
H65.3 Chronic mucoid otitis media
0.528 0.472 0.000
M50-M54 Other dorsopathies
0.527 0.473 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.527 0.473 0.000
H72.8 Other perforations of tympanic membrane
0.527 0.473 0.000
H72.2 Other marginal perforations of tympanic membrane
0.527 0.473 0.000
H72.1 Attic perforation of tympanic membrane
0.527 0.473 0.000
H81.1 Benign paroxysmal vertigo
0.525 0.475 0.000
N62 Hypertrophy of breast
0.525 0.475 0.000
N61 Inflammatory disorders of breast
0.525 0.475 0.000
S02 Fracture of skull and facial bones
0.525 0.475 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.524 0.476 0.000
S01 Open wound of head
0.522 0.477 0.000
O03 Spontaneous abortion
0.520 0.480 0.000
C51-C58 Malignant neoplasms of female genital organs
0.519 0.481 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.519 0.481 0.000
N27 Small kidney of unknown cause
0.519 0.481 0.000
N25 Disorders resulting from impaired renal tubular function
0.519 0.481 0.000
N26 Unspecified contracted kidney
0.519 0.481 0.000
H81.0 Meniere's disease
0.518 0.482 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.517 0.483 0.000
O07 Failed attempted abortion
0.517 0.483 0.000
O06 Unspecified abortion
0.517 0.483 0.000
O05 Other abortion
0.517 0.483 0.000
O01 Hydatidiform mole
0.517 0.483 0.000
O00 Ectopic pregnancy
0.517 0.483 0.000
D11 Benign neoplasm of major salivary glands
0.515 0.485 0.000
N45 Orchitis and epididymitis
0.515 0.485 0.000
O82 Single delivery by Caesarean section
0.515 0.485 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.515 0.485 0.000
L20-L30 Dermatitis and eczema
0.514 0.486 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.514 0.486 0.000
N39.4 Other specified urinary incontinence
0.513 0.487 0.000
E05.9 Thyrotoxicosis, unspecified
0.513 0.487 0.000
B99-B99 Other infectious diseases
0.513 0.487 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.513 0.487 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.513 0.487 0.000
B65-B83 Helminthiases
0.513 0.487 0.000
B50-B64 Protozoal diseases
0.513 0.487 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.513 0.487 0.000
B15-B19 Viral hepatitis
0.513 0.487 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.513 0.487 0.000
A80-A89 Viral infections of the central nervous system
0.513 0.487 0.000
A75-A79 Rickettsioses
0.513 0.487 0.000
A70-A74 Other diseases caused by chlamydiae
0.513 0.487 0.000
A65-A69 Other spirochaetal diseases
0.513 0.487 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.513 0.487 0.000
A20-A28 Certain zoonotic bacterial diseases
0.513 0.487 0.000
A15-A19 Tuberculosis
0.513 0.487 0.000
S08 Traumatic amputation of part of head
0.512 0.488 0.000
S07 Crushing injury of head
0.512 0.488 0.000
S06 Intracranial injury
0.512 0.488 0.000
S05 Injury of eye and orbit
0.512 0.488 0.000
S04 Injury of cranial nerves
0.512 0.488 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.512 0.488 0.000
J22 Unspecified acute lower respiratory infection
0.511 0.489 0.000
C34.1 Upper lobe, bronchus or lung
0.510 0.490 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.510 0.490 0.000
N89 Other noninflammatory disorders of vagina
0.510 0.490 0.000
O15 Eclampsia
0.509 0.490 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.509 0.490 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.509 0.490 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.509 0.490 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.509 0.490 0.000
S82 Fracture of lower leg, including ankle
0.509 0.491 0.000
N36.9 Urethral disorder, unspecified
0.508 0.491 0.000
N36.3 Prolapsed urethral mucosa
0.508 0.491 0.000
N36.2 Urethral caruncle
0.508 0.491 0.000
N36.1 Urethral diverticulum
0.508 0.491 0.000
N36.0 Urethral fistula
0.508 0.491 0.000
N50.1 Vascular disorders of male genital organs
0.508 0.492 0.000
Z37.2 Twins, both liveborn
0.508 0.492 0.000
E04.2 Non-toxic multinodular goitre
0.507 0.493 0.000
Z47 Other orthopaedic follow-up care
0.507 0.493 0.000
A00-A09 Intestinal infectious diseases
0.507 0.493 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.505 0.495 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.501 0.499 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.500 0.500 0.000
N15 Other renal tubulo-interstitial diseases
0.500 0.500 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.500 0.500 0.000
N11 Chronic tubulo-interstitial nephritis
0.500 0.500 0.000
N10 Acute tubulo-interstitial nephritis
0.500 0.500 0.000
N93 Other abnormal uterine and vaginal bleeding
0.499 0.501 0.000
L50-L54 Urticaria and erythema
0.499 0.501 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.498 0.502 0.000
S09 Other and unspecified injuries of head
0.498 0.502 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.497 0.503 0.000
L40-L45 Papulosquamous disorders
0.496 0.504 0.000
C34.9 Bronchus or lung, unspecified
0.495 0.505 0.000
B35-B49 Mycoses
0.495 0.505 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.493 0.507 0.000
S52 Fracture of forearm
0.492 0.508 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.490 0.510 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.490 0.510 0.000
C32 Malignant neoplasm of larynx
0.490 0.510 0.000
C31 Malignant neoplasm of accessory sinuses
0.490 0.510 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.490 0.510 0.000
C37 Malignant neoplasm of thymus
0.490 0.510 0.000
C33 Malignant neoplasm of trachea
0.490 0.510 0.000
D36 Benign neoplasm of other and unspecified sites
0.490 0.510 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.490 0.510 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.490 0.510 0.000
D32 Benign neoplasm of meninges
0.490 0.510 0.000
D31 Benign neoplasm of eye and adnexa
0.490 0.510 0.000
D30 Benign neoplasm of urinary organs
0.490 0.510 0.000
D29 Benign neoplasm of male genital organs
0.490 0.510 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.490 0.510 0.000
D26 Other benign neoplasms of uterus
0.490 0.510 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.490 0.510 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.490 0.510 0.000
D19 Benign neoplasm of mesothelial tissue
0.490 0.510 0.000
D16 Benign neoplasm of bone and articular cartilage
0.490 0.510 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.490 0.510 0.000
D10 Benign neoplasm of mouth and pharynx
0.490 0.510 0.000
D34 Benign neoplasm of thyroid gland
0.490 0.510 0.000
C64-C68 Malignant neoplasms of urinary tract
0.490 0.510 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.489 0.511 0.000
L10-L14 Bullous disorders
0.488 0.512 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.488 0.512 0.000
D05 Carcinoma in situ of breast
0.488 0.512 0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified
0.487 0.513 0.000
O64.8 Obstructed labour due to other malposition and malpresentation
0.487 0.513 0.000
O64.5 Obstructed labour due to compound presentation
0.487 0.513 0.000
O64.4 Obstructed labour due to shoulder presentation
0.487 0.513 0.000
O64.3 Obstructed labour due to brow presentation
0.487 0.513 0.000
O64.2 Obstructed labour due to face presentation
0.487 0.513 0.000
O64.1 Obstructed labour due to breech presentation
0.487 0.513 0.000
N70.1 Chronic salpingitis and oophoritis
0.485 0.514 0.000
N87 Dysplasia of cervix uteri
0.484 0.516 0.000
N50.8 Other specified disorders of male genital organs
0.484 0.516 0.000
S92 Fracture of foot, except ankle
0.484 0.516 0.000
N21 Calculus of lower urinary tract
0.484 0.516 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.483 0.517 0.000
T81 Complications of procedures, not elsewhere classified
0.483 0.517 0.000
N39.8 Other specified disorders of urinary system
0.482 0.517 0.000
N39.2 Orthostatic proteinuria, unspecified
0.482 0.517 0.000
N39.1 Persistent proteinuria, unspecified
0.482 0.517 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.482 0.517 0.000
T87 Complications peculiar to reattachment and amputation
0.482 0.517 0.000
T86 Failure and rejection of transplanted organs and tissues
0.482 0.517 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.482 0.517 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.482 0.517 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.482 0.518 0.000
Q80-Q89 Other congenital malformations
0.482 0.518 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.482 0.518 0.000
Q60-Q64 Congenital malformations of the urinary system
0.482 0.518 0.000
Q50-Q56 Congenital malformations of genital organs
0.482 0.518 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.482 0.518 0.000
Q35-Q37 Cleft lip and cleft palate
0.482 0.518 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.482 0.518 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.482 0.518 0.000
Q00-Q07 Congenital malformations of the nervous system
0.482 0.518 0.000
H83.9 Disease of inner ear, unspecified
0.482 0.518 0.000
H83.8 Other specified diseases of inner ear
0.482 0.518 0.000
H83.3 Noise effects on inner ear
0.482 0.518 0.000
H83.2 Labyrinthine dysfunction
0.482 0.518 0.000
H83.1 Labyrinthine fistula
0.482 0.518 0.000
T51 Toxic effect of alcohol
0.482 0.518 0.000
E04.9 Non-toxic goitre, unspecified
0.482 0.518 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.481 0.518 0.000
M86-M90 Other osteopathies
0.481 0.519 0.000
O84 Multiple delivery
0.480 0.519 0.000
O83 Other assisted single delivery
0.480 0.519 0.000
O81 Single delivery by forceps and vacuum extractor
0.480 0.519 0.000
N86 Erosion and ectropion of cervix uteri
0.480 0.520 0.000
Z48 Other surgical follow-up care
0.480 0.520 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.479 0.521 0.000
N39.0 Urinary tract infection, site not specified
0.475 0.525 0.000
O63.0 Prolonged first stage (of labour)
0.475 0.525 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.475 0.525 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.474 0.525 0.000
J90-J94 Other diseases of pleura
0.474 0.525 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.474 0.526 0.000
Z33 Pregnant state, incidental
0.472 0.527 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.472 0.528 0.000
E03.8 Other specified hypothyroidism
0.472 0.528 0.000
E03.5 Myxoedema coma
0.472 0.528 0.000
E03.4 Atrophy of thyroid (acquired)
0.472 0.528 0.000
E03.3 Postinfectious hypothyroidism
0.472 0.528 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.472 0.528 0.000
E03.1 Congenital hypothyroidism without goitre
0.472 0.528 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.472 0.528 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.471 0.529 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.471 0.529 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.471 0.529 0.000
O34.6 Maternal care for abnormality of vagina
0.471 0.529 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.471 0.529 0.000
O34.4 Maternal care for other abnormalities of cervix
0.471 0.529 0.000
O34.3 Maternal care for cervical incompetence
0.471 0.529 0.000
O34.1 Maternal care for tumour of corpus uteri
0.471 0.529 0.000
O34.0 Maternal care for congenital malformation of uterus
0.471 0.529 0.000
S89 Other and unspecified injuries of lower leg
0.471 0.529 0.000
S88 Traumatic amputation of lower leg
0.471 0.529 0.000
S87 Crushing injury of lower leg
0.471 0.529 0.000
S86 Injury of muscle and tendon at lower leg level
0.471 0.529 0.000
S85 Injury of blood vessels at lower leg level
0.471 0.529 0.000
S84 Injury of nerves at lower leg level
0.471 0.529 0.000
S81 Open wound of lower leg
0.471 0.529 0.000
S80 Superficial injury of lower leg
0.471 0.529 0.000
Z45 Adjustment and management of implanted device
0.471 0.529 0.000
J30 Vasomotor and allergic rhinitis
0.470 0.530 0.000
D23 Other benign neoplasms of skin
0.470 0.530 0.000
S29 Other and unspecified injuries of thorax
0.469 0.530 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.469 0.530 0.000
S27 Injury of other and unspecified intrathoracic organs
0.469 0.530 0.000
S26 Injury of heart
0.469 0.530 0.000
S25 Injury of blood vessels of thorax
0.469 0.530 0.000
S24 Injury of nerves and spinal cord at thorax level
0.469 0.530 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.469 0.530 0.000
S21 Open wound of thorax
0.469 0.530 0.000
S20 Superficial injury of thorax
0.469 0.530 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.469 0.531 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.469 0.531 0.000
O42.9 Premature rupture of membranes, unspecified
0.469 0.531 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.469 0.531 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.469 0.531 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.469 0.531 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.469 0.531 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.469 0.531 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.469 0.531 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.469 0.531 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.469 0.531 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.469 0.531 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.469 0.531 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.469 0.531 0.000
T36 Poisoning by systemic antibiotics
0.469 0.531 0.000
O36.8 Maternal care for other specified foetal problems
0.469 0.531 0.000
P90-P96 Other disorders originating in the perinatal period
0.469 0.531 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.469 0.531 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.469 0.531 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.469 0.531 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.469 0.531 0.000
P35-P39 Infections specific to the perinatal period
0.469 0.531 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.469 0.531 0.000
P10-P15 Birth trauma
0.469 0.531 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.469 0.531 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.469 0.531 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.469 0.531 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.469 0.531 0.000
H81.9 Disorder of vestibular function, unspecified
0.468 0.532 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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