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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs146346907
log Bayes Factor = 0.00013263
Chromosome 13   position 109,033,271  (GRCh37) Explore rs146346907 on Ensembl!
Variant rs146346907 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
0.000 0.999 0.001
I10-I15 Hypertensive diseases
0.000 0.999 0.001
I15 Secondary hypertension
0.000 0.999 0.001
I13 Hypertensive heart and renal disease
0.000 0.999 0.001
I12 Hypertensive renal disease
0.000 0.999 0.001
I11 Hypertensive heart disease
0.000 0.999 0.001
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.999 0.001
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.999 0.001
I12.9 Hypertensive renal disease without renal failure
0.000 0.999 0.001
I12.0 Hypertensive renal disease with renal failure
0.000 0.999 0.001
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.999 0.001
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.999 0.001
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.999 0.001
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.999 0.001
I15.9 Seconday hypertension, unspecified
0.000 0.999 0.001
I15.8 Other secondary hypertension
0.000 0.999 0.001
I15.2 Hypertension secondary to endocrine disorders
0.000 0.999 0.001
I15.1 Hypertension secondary to other renal disorders
0.000 0.999 0.001
I15.0 Renovascular hypertension
0.000 0.999 0.001
R69 Unknown and unspecified causes of morbidity
0.001 0.999 0.000
Chapter IX Diseases of the circulatory system
0.001 0.999 0.001
I25.9 Chronic ischaemic heart disease, unspecified
0.001 0.999 0.000
I20-I25 Ischaemic heart diseases
0.001 0.999 0.001
R50-R69 General symptoms and signs
0.001 0.999 0.000
I25 Chronic ischaemic heart disease
0.001 0.999 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.001 0.999 0.001
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.001 0.999 0.001
I70-I79 Diseases of arteries, arterioles and capillaries
0.001 0.999 0.001
I60-I69 Cerebrovascular diseases
0.001 0.999 0.001
I30-I52 Other forms of heart disease
0.001 0.999 0.001
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.999 0.001
I05-I09 Chronic rheumatic heart diseases
0.001 0.999 0.001
I00-I02 Acute rheumatic fever
0.001 0.999 0.001
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.001 0.999 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.001 0.999 0.000
I25.6 Silent myocardial ischaemia
0.001 0.999 0.000
I25.5 Ischaemic cardiomyopathy
0.001 0.999 0.000
I25.4 Coronary artery aneurysm
0.001 0.999 0.000
I25.3 Aneurysm of heart
0.001 0.999 0.000
I25.2 Old myocardial infarction
0.001 0.999 0.000
I25.1 Atherosclerotic heart disease
0.001 0.999 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.001 0.999 0.000
I02 Rheumatic chorea
0.001 0.999 0.001
I01 Rheumatic fever with heart involvement
0.001 0.999 0.001
I00 Rheumatic fever without mention of heart involvement
0.001 0.999 0.001
I09 Other rheumatic heart diseases
0.001 0.999 0.001
I08 Multiple valve diseases
0.001 0.999 0.001
I07 Rheumatic tricuspid valve diseases
0.001 0.999 0.001
I06 Rheumatic aortic valve diseases
0.001 0.999 0.001
I05 Rheumatic mitral valve diseases
0.001 0.999 0.001
I24 Other acute ischaemic heart diseases
0.001 0.999 0.001
I23 Certain current complications following acute myocardial infarction
0.001 0.999 0.001
I22 Subsequent myocardial infarction
0.001 0.999 0.001
I21 Acute myocardial infarction
0.001 0.999 0.001
I20 Angina pectoris
0.001 0.999 0.001
I28 Other diseases of pulmonary vessels
0.001 0.999 0.001
I27 Other pulmonary heart diseases
0.001 0.999 0.001
I26 Pulmonary embolism
0.001 0.999 0.001
I52 Other heart disorders in diseases classified elsewhere
0.001 0.999 0.001
I51 Complications and ill-defined descriptions of heart disease
0.001 0.999 0.001
I50 Heart failure
0.001 0.999 0.001
I49 Other cardiac arrhythmias
0.001 0.999 0.001
I48 Atrial fibrillation and flutter
0.001 0.999 0.001
I47 Paroxysmal tachycardia
0.001 0.999 0.001
I46 Cardiac arrest
0.001 0.999 0.001
I45 Other conduction disorders
0.001 0.999 0.001
I44 Atrioventricular and left bundle-branch block
0.001 0.999 0.001
I43 Cardiomyopathy in diseases classified elsewhere
0.001 0.999 0.001
I42 Cardiomyopathy
0.001 0.999 0.001
I41 Myocarditis in diseases classified elsewhere
0.001 0.999 0.001
I40 Acute myocarditis
0.001 0.999 0.001
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.001 0.999 0.001
I37 Pulmonary valve disorders
0.001 0.999 0.001
I36 Nonrheumatic tricuspid valve disorders
0.001 0.999 0.001
I35 Nonrheumatic aortic valve disorders
0.001 0.999 0.001
I34 Nonrheumatic mitral valve disorders
0.001 0.999 0.001
I33 Acute and subacute endocarditis
0.001 0.999 0.001
I32 Pericarditis in diseases classified elsewhere
0.001 0.999 0.001
I31 Other diseases of pericardium
0.001 0.999 0.001
I30 Acute pericarditis
0.001 0.999 0.001
I38 Endocarditis, valve unspecified
0.001 0.999 0.001
I69 Sequelae of cerebrovascular disease
0.001 0.999 0.001
I68 Cerebrovascular disorders in diseases classified elsewhere
0.001 0.999 0.001
I67 Other cerebrovascular diseases
0.001 0.999 0.001
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.001 0.999 0.001
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.001 0.999 0.001
I63 Cerebral infarction
0.001 0.999 0.001
I62 Other nontraumatic intracranial haemorrhage
0.001 0.999 0.001
I61 Intracerebral haemorrhage
0.001 0.999 0.001
I60 Subarachnoid haemorrhage
0.001 0.999 0.001
I64 Stroke, not specified as haemorrhage or infarction
0.001 0.999 0.001
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.001 0.999 0.001
I78 Diseases of capillaries
0.001 0.999 0.001
I77 Other disorders of arteries and arterioles
0.001 0.999 0.001
I74 Arterial embolism and thrombosis
0.001 0.999 0.001
I73 Other peripheral vascular diseases
0.001 0.999 0.001
I72 Other aneurysm
0.001 0.999 0.001
I71 Aortic aneurysm and dissection
0.001 0.999 0.001
I70 Atherosclerosis
0.001 0.999 0.001
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.001 0.999 0.001
I88 Nonspecific lymphadenitis
0.001 0.999 0.001
I87 Other disorders of veins
0.001 0.999 0.001
I86 Varicose veins of other sites
0.001 0.999 0.001
I85 Oesophageal varices
0.001 0.999 0.001
I84 Haemorrhoids
0.001 0.999 0.001
I83 Varicose veins of lower extremities
0.001 0.999 0.001
I82 Other venous embolism and thrombosis
0.001 0.999 0.001
I80 Phlebitis and thrombophlebitis
0.001 0.999 0.001
I81 Portal vein thrombosis
0.001 0.999 0.001
I98 Other disorders of circulatory system in diseases classified elsewhere
0.001 0.999 0.001
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.999 0.001
I95 Hypotension
0.001 0.999 0.001
I99 Other and unspecified disorders of circulatory system
0.001 0.999 0.001
R68 Other general symptoms and signs
0.001 0.999 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.001 0.999 0.000
R63 Symptoms and signs concerning food and fluid intake
0.001 0.999 0.000
R62 Lack of expected normal physiological development
0.001 0.999 0.000
R61 Hyperhidrosis
0.001 0.999 0.000
R60 Oedema, not elsewhere classified
0.001 0.999 0.000
R59 Enlarged lymph nodes
0.001 0.999 0.000
R57 Shock, not elsewhere classified
0.001 0.999 0.000
R56 Convulsions, not elsewhere classified
0.001 0.999 0.000
R52 Pain, not elsewhere classified
0.001 0.999 0.000
R50 Fever of unknown origin
0.001 0.999 0.000
R64 Cachexia
0.001 0.999 0.000
R58 Haemorrhage, not elsewhere classified
0.001 0.999 0.000
R55 Syncope and collapse
0.001 0.999 0.000
R54 Senility
0.001 0.999 0.000
R53 Malaise and fatigue
0.001 0.999 0.000
R51 Headache
0.001 0.999 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.001 0.999 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.001 0.999 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.001 0.999 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.001 0.999 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.001 0.999 0.000
R47-R49 Symptoms and signs involving speech and voice
0.001 0.999 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.001 0.999 0.000
R30-R39 Symptoms and signs involving the urinary system
0.001 0.999 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.001 0.999 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.001 0.999 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.001 0.999 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.001 0.999 0.000
# Top node
0.001 0.999 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.001 0.999 0.001
I01.8 Other acute rheumatic heart disease
0.001 0.999 0.001
I01.2 Acute rheumatic myocarditis
0.001 0.999 0.001
I01.1 Acute rheumatic endocarditis
0.001 0.999 0.001
I01.0 Acute rheumatic pericarditis
0.001 0.999 0.001
I02.9 Rheumatic chorea without heart involvement
0.001 0.999 0.001
I02.0 Rheumatic chorea with heart involvement
0.001 0.999 0.001
I05.9 Mitral valve disease, unspecified
0.001 0.999 0.001
I05.8 Other mitral valve diseases
0.001 0.999 0.001
I05.2 Mitral stenosis with insufficiency
0.001 0.999 0.001
I05.1 Rheumatic mitral insufficiency
0.001 0.999 0.001
I05.0 Mitral stenosis
0.001 0.999 0.001
I06.9 Rheumatic aortic valve disease, unspecified
0.001 0.999 0.001
I06.8 Other rheumatic aortic valve diseases
0.001 0.999 0.001
I06.2 Rheumatic aortic stenosis with insufficiency
0.001 0.999 0.001
I06.1 Rheumatic aortic insufficiency
0.001 0.999 0.001
I06.0 Rheumatic aortic stenosis
0.001 0.999 0.001
I07.9 Tricuspid valve disease, unspecified
0.001 0.999 0.001
I07.8 Other tricuspid valve diseases
0.001 0.999 0.001
I07.2 Tricuspid stenosis with insufficiency
0.001 0.999 0.001
I07.1 Tricuspid insufficiency
0.001 0.999 0.001
I07.0 Tricuspid stenosis
0.001 0.999 0.001
I08.9 Multiple valve disease, unspecified
0.001 0.999 0.001
I08.8 Other multiple valve diseases
0.001 0.999 0.001
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.001 0.999 0.001
I08.2 Disorders of both aortic and tricuspid valves
0.001 0.999 0.001
I08.1 Disorders of both mitral and tricuspid valves
0.001 0.999 0.001
I08.0 Disorders of both mitral and aortic valves
0.001 0.999 0.001
I09.9 Rheumatic heart disease, unspecified
0.001 0.999 0.001
I09.8 Other specified rheumatic heart diseases
0.001 0.999 0.001
I09.2 Chronic rheumatic pericarditis
0.001 0.999 0.001
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.001 0.999 0.001
I09.0 Rheumatic myocarditis
0.001 0.999 0.001
I20.9 Angina pectoris, unspecified
0.001 0.999 0.001
I20.8 Other forms of angina pectoris
0.001 0.999 0.001
I20.1 Angina pectoris with documented spasm
0.001 0.999 0.001
I20.0 Unstable angina
0.001 0.999 0.001
I21.X Presumed acute myicardial infaction (unconfirmed)
0.001 0.999 0.001
I21.9 Acute myocardial infarction, unspecified
0.001 0.999 0.001
I21.4 Acute subendocardial myocardial infarction
0.001 0.999 0.001
I21.3 Acute transmural myocardial infarction of unspecified site
0.001 0.999 0.001
I21.2 Acute transmural myocardial infarction of other sites
0.001 0.999 0.001
I21.1 Acute transmural myocardial infarction of inferior wall
0.001 0.999 0.001
I21.0 Acute transmural myocardial infarction of anterior wall
0.001 0.999 0.001
I22.9 Subsequent myocardial infarction of unspecified site
0.001 0.999 0.001
I22.8 Subsequent myocardial infarction of other sites
0.001 0.999 0.001
I22.1 Subsequent myocardial infarction of inferior wall
0.001 0.999 0.001
I22.0 Subsequent myocardial infarction of anterior wall
0.001 0.999 0.001
I23.8 Other current complications following acute myocardial infarction
0.001 0.999 0.001
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.001 0.999 0.001
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.001 0.999 0.001
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.001 0.999 0.001
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.001 0.999 0.001
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.001 0.999 0.001
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.001 0.999 0.001
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.001 0.999 0.001
I24.9 Acute ischaemic heart disease, unspecified
0.001 0.999 0.001
I24.8 Other forms of acute ischaemic heart disease
0.001 0.999 0.001
I24.1 Dressler's syndrome
0.001 0.999 0.001
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.001 0.999 0.001
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.001 0.999 0.001
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.001 0.999 0.001
I27.9 Pulmonary heart disease, unspecified
0.001 0.999 0.001
I27.8 Other specified pulmonary heart diseases
0.001 0.999 0.001
I27.2 Other secondary pulmonary hypertension
0.001 0.999 0.001
I27.1 Kyphoscoliotic heart disease
0.001 0.999 0.001
I27.0 Primary pulmonary hypertension
0.001 0.999 0.001
I28.9 Disease of pulmonary vessels, unspecified
0.001 0.999 0.001
I28.8 Other specified diseases of pulmonary vessels
0.001 0.999 0.001
I28.1 Aneurysm of pulmonary artery
0.001 0.999 0.001
I28.0 Arteriovenous fistula of pulmonary vessels
0.001 0.999 0.001
I30.9 Acute pericarditis, unspecified
0.001 0.999 0.001
I30.8 Other forms of acute pericarditis
0.001 0.999 0.001
I30.1 Infective pericarditis
0.001 0.999 0.001
I30.0 Acute nonspecific idiopathic pericarditis
0.001 0.999 0.001
I31.9 Disease of pericardium, unspecified
0.001 0.999 0.001
I31.8 Other specified diseases of pericardium
0.001 0.999 0.001
I31.3 Pericardial effusion (noninflammatory)
0.001 0.999 0.001
I31.2 Haemopericardium, not elsewhere classified
0.001 0.999 0.001
I31.1 Chronic constrictive pericarditis
0.001 0.999 0.001
I31.0 Chronic adhesive pericarditis
0.001 0.999 0.001
I32.8 Pericarditis in other diseases classified elsewhere
0.001 0.999 0.001
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.001 0.999 0.001
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.001 0.999 0.001
I33.9 Acute endocarditis, unspecified
0.001 0.999 0.001
I33.0 Acute and subacute infective endocarditis
0.001 0.999 0.001
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.001 0.999 0.001
I34.8 Other nonrheumatic mitral valve disorders
0.001 0.999 0.001
I34.2 Nonrheumatic mitral (valve) stenosis
0.001 0.999 0.001
I34.1 Mitral (valve) prolapse
0.001 0.999 0.001
I34.0 Mitral (valve) insufficiency
0.001 0.999 0.001
I35.9 Aortic valve disorder, unspecified
0.001 0.999 0.001
I35.8 Other aortic valve disorders
0.001 0.999 0.001
I35.2 Aortic (valve) stenosis with insufficiency
0.001 0.999 0.001
I35.1 Aortic (valve) insufficiency
0.001 0.999 0.001
I35.0 Aortic (valve) stenosis
0.001 0.999 0.001
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.001 0.999 0.001
I36.8 Other nonrheumatic tricuspid valve disorders
0.001 0.999 0.001
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.001 0.999 0.001
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.001 0.999 0.001
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.001 0.999 0.001
I37.9 Pulmonary valve disorder, unspecified
0.001 0.999 0.001
I37.8 Other pulmonary valve disorders
0.001 0.999 0.001
I37.2 Pulmonary valve stenosis with insufficiency
0.001 0.999 0.001
I37.1 Pulmonary valve insufficiency
0.001 0.999 0.001
I37.0 Pulmonary valve stenosis
0.001 0.999 0.001
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.001 0.999 0.001
I39.4 Multiple valve disorders in diseases classified elsewhere
0.001 0.999 0.001
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.001 0.999 0.001
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.001 0.999 0.001
I39.1 Aortic valve disorders in diseases classified elsewhere
0.001 0.999 0.001
I39.0 Mitral valve disorders in diseases classified elsewhere
0.001 0.999 0.001
I40.9 Acute myocarditis, unspecified
0.001 0.999 0.001
I40.8 Other acute myocarditis
0.001 0.999 0.001
I40.1 Isolated myocarditis
0.001 0.999 0.001
I40.0 Infective myocarditis
0.001 0.999 0.001
I41.8 Myocarditis in other diseases classified elsewhere
0.001 0.999 0.001
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.001 0.999 0.001
I41.1 Myocarditis in viral diseases classified elsewhere
0.001 0.999 0.001
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.001 0.999 0.001
I42.9 Cardiomyopathy, unspecified
0.001 0.999 0.001
I42.8 Other cardiomyopathies
0.001 0.999 0.001
I42.7 Cardiomyopathy due to drugs and other external agents
0.001 0.999 0.001
I42.6 Alcoholic cardiomyopathy
0.001 0.999 0.001
I42.5 Other restrictive cardiomyopathy
0.001 0.999 0.001
I42.4 Endocardial fibroelastosis
0.001 0.999 0.001
I42.3 Endomyocardial (eosinophilic) disease
0.001 0.999 0.001
I42.2 Other hypertrophic cardiomyopathy
0.001 0.999 0.001
I42.1 Obstructive hypertrophic cardiomyopathy
0.001 0.999 0.001
I42.0 Dilated cardiomyopathy
0.001 0.999 0.001
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.001 0.999 0.001
I43.2 Cardiomyopathy in nutritional diseases
0.001 0.999 0.001
I43.1 Cardiomyopathy in metabolic diseases
0.001 0.999 0.001
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.001 0.999 0.001
I44.7 Left bundle-branch block, unspecified
0.001 0.999 0.001
I44.6 Other and unspecified fascicular block
0.001 0.999 0.001
I44.5 Left posterior fascicular block
0.001 0.999 0.001
I44.4 Left anterior fascicular block
0.001 0.999 0.001
I44.3 Other and unspecified atrioventricular block
0.001 0.999 0.001
I44.2 Atrioventricular block, complete
0.001 0.999 0.001
I44.1 Atrioventricular block, second degree
0.001 0.999 0.001
I44.0 Atrioventricular block, first degree
0.001 0.999 0.001
I45.9 Conduction disorder, unspecified
0.001 0.999 0.001
I45.8 Other specified conduction disorders
0.001 0.999 0.001
I45.6 Preexcitation syndrome
0.001 0.999 0.001
I45.5 Other specified heart block
0.001 0.999 0.001
I45.4 Nonspecific intraventricular block
0.001 0.999 0.001
I45.3 Trifascicular block
0.001 0.999 0.001
I45.2 Bifascicular block
0.001 0.999 0.001
I45.1 Other and unspecified right bundle-branch block
0.001 0.999 0.001
I45.0 Right fascicular block
0.001 0.999 0.001
I46.9 Cardiac arrest, unspecified
0.001 0.999 0.001
I46.1 Sudden cardiac death, so described
0.001 0.999 0.001
I46.0 Cardiac arrest with successful resuscitation
0.001 0.999 0.001
I47.9 Paroxysmal tachycardia, unspecified
0.001 0.999 0.001
I47.2 Ventricular tachycardia
0.001 0.999 0.001
I47.1 Supraventricular tachycardia
0.001 0.999 0.001
I47.0 Reentry ventricular arrhythmia
0.001 0.999 0.001
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.001 0.999 0.001
I48.4 Atypical atrial flutter
0.001 0.999 0.001
I48.3 Typical atrial flutter
0.001 0.999 0.001
I48.2 Chronic atrial fibrillation
0.001 0.999 0.001
I48.1 Persistent atrial fibrillation
0.001 0.999 0.001
I48.0 Paroxysmal atrial fibrillation
0.001 0.999 0.001
I49.9 Cardiac arrhythmia, unspecified
0.001 0.999 0.001
I49.8 Other specified cardiac arrhythmias
0.001 0.999 0.001
I49.5 Sick sinus syndrome
0.001 0.999 0.001
I49.4 Other and unspecified premature depolarisation
0.001 0.999 0.001
I49.3 Ventricular premature depolarisation
0.001 0.999 0.001
I49.2 Junctional premature depolarisation
0.001 0.999 0.001
I49.1 Atrial premature depolarisation
0.001 0.999 0.001
I49.0 Ventricular fibrillation and flutter
0.001 0.999 0.001
I50.9 Heart failure, unspecified
0.001 0.999 0.001
I50.1 Left ventricular failure
0.001 0.999 0.001
I50.0 Congestive heart failure
0.001 0.999 0.001
I51.9 Heart disease, unspecified
0.001 0.999 0.001
I51.8 Other ill-defined heart diseases
0.001 0.999 0.001
I51.7 Cardiomegaly
0.001 0.999 0.001
I51.6 Cardiovascular disease, unspecified
0.001 0.999 0.001
I51.5 Myocardial degeneration
0.001 0.999 0.001
I51.4 Myocarditis, unspecified
0.001 0.999 0.001
I51.3 Intracardiac thrombosis, not elsewhere classified
0.001 0.999 0.001
I51.2 Rupture of papillary muscle, not elsewhere classified
0.001 0.999 0.001
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.001 0.999 0.001
I51.0 Cardiac septal defect, acquired
0.001 0.999 0.001
I52.8 Other heart disorders in other diseases classified elsewhere
0.001 0.999 0.001
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.001 0.999 0.001
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.001 0.999 0.001
I60.9 Subarachnoid haemorrhage, unspecified
0.001 0.999 0.001
I60.8 Other subarachnoid haemorrhage
0.001 0.999 0.001
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.001 0.999 0.001
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.001 0.999 0.001
I60.5 Subarachnoid haemorrhage from vertebral artery
0.001 0.999 0.001
I60.4 Subarachnoid haemorrhage from basilar artery
0.001 0.999 0.001
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.001 0.999 0.001
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.001 0.999 0.001
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.001 0.999 0.001
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.001 0.999 0.001
I61.9 Intracerebral haemorrhage, unspecified
0.001 0.999 0.001
I61.8 Other intracerebral haemorrhage
0.001 0.999 0.001
I61.6 Intracerebral haemorrhage, multiple localised
0.001 0.999 0.001
I61.5 Intracerebral haemorrhage, intraventricular
0.001 0.999 0.001
I61.4 Intracerebral haemorrhage in cerebellum
0.001 0.999 0.001
I61.3 Intracerebral haemorrhage in brain stem
0.001 0.999 0.001
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.001 0.999 0.001
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.001 0.999 0.001
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.001 0.999 0.001
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.001 0.999 0.001
I62.1 Nontraumatic extradural haemorrhage
0.001 0.999 0.001
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.001 0.999 0.001
I63.9 Cerebral infarction, unspecified
0.001 0.999 0.001
I63.8 Other cerebral infarction
0.001 0.999 0.001
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.001 0.999 0.001
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.001 0.999 0.001
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.001 0.999 0.001
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.001 0.999 0.001
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.001 0.999 0.001
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.001 0.999 0.001
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.001 0.999 0.001
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.001 0.999 0.001
I65.8 Occlusion and stenosis of other precerebral artery
0.001 0.999 0.001
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.001 0.999 0.001
I65.2 Occlusion and stenosis of carotid artery
0.001 0.999 0.001
I65.1 Occlusion and stenosis of basilar artery
0.001 0.999 0.001
I65.0 Occlusion and stenosis of vertebral artery
0.001 0.999 0.001
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.001 0.999 0.001
I66.8 Occlusion and stenosis of other cerebral artery
0.001 0.999 0.001
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.001 0.999 0.001
I66.3 Occlusion and stenosis of cerebellar arteries
0.001 0.999 0.001
I66.2 Occlusion and stenosis of posterior cerebral artery
0.001 0.999 0.001
I66.1 Occlusion and stenosis of anterior cerebral artery
0.001 0.999 0.001
I66.0 Occlusion and stenosis of middle cerebral artery
0.001 0.999 0.001
I67.9 Cerebrovascular disease, unspecified
0.001 0.999 0.001
I67.8 Other specified cerebrovascular diseases
0.001 0.999 0.001
I67.7 Cerebral arteritis, not elsewhere classified
0.001 0.999 0.001
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.001 0.999 0.001
I67.5 Moyamoya disease
0.001 0.999 0.001
I67.4 Hypertensive encephalopathy
0.001 0.999 0.001
I67.3 Progressive vascular leukoencephalopathy
0.001 0.999 0.001
I67.2 Cerebral atherosclerosis
0.001 0.999 0.001
I67.1 Cerebral aneurysm, nonruptured
0.001 0.999 0.001
I67.0 Dissection of cerebral arteries, nonruptured
0.001 0.999 0.001
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.001 0.999 0.001
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.001 0.999 0.001
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.001 0.999 0.001
I68.0 Cerebral amyloid angiopathy
0.001 0.999 0.001
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.001 0.999 0.001
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.001 0.999 0.001
I69.3 Sequelae of cerebral infarction
0.001 0.999 0.001
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.001 0.999 0.001
I69.1 Sequelae of intracerebral haemorrhage
0.001 0.999 0.001
I69.0 Sequelae of subarachnoid haemorrhage
0.001 0.999 0.001
I70.9 Generalised and unspecified atherosclerosis
0.001 0.999 0.001
I70.8 Atherosclerosis of other arteries
0.001 0.999 0.001
I70.2 Atherosclerosis of arteries of the extremities
0.001 0.999 0.001
I70.1 Atherosclerosis of renal artery
0.001 0.999 0.001
I70.0 Atherosclerosis of aorta
0.001 0.999 0.001
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.001 0.999 0.001
I71.8 Aortic aneurysm of unspecified site, ruptured
0.001 0.999 0.001
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.001 0.999 0.001
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.001 0.999 0.001
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.001 0.999 0.001
I71.3 Abdominal aortic aneurysm, ruptured
0.001 0.999 0.001
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.001 0.999 0.001
I71.1 Thoracic aortic aneurysm, ruptured
0.001 0.999 0.001
I71.0 Dissection of aorta [any part]
0.001 0.999 0.001
I72.9 Aneurysm of unspecified site
0.001 0.999 0.001
I72.8 Aneurysm of other specified arteries
0.001 0.999 0.001
I72.6 Aneurysm and dissection of vertebral artery
0.001 0.999 0.001
I72.5 Aneurysm and dissection of other precerebral arteries
0.001 0.999 0.001
I72.4 Aneurysm of artery of lower extremity
0.001 0.999 0.001
I72.3 Aneurysm of iliac artery
0.001 0.999 0.001
I72.2 Aneurysm of renal artery
0.001 0.999 0.001
I72.1 Aneurysm of artery of upper extremity
0.001 0.999 0.001
I72.0 Aneurysm of carotid artery
0.001 0.999 0.001
I73.9 Peripheral vascular disease, unspecified
0.001 0.999 0.001
I73.8 Other specified peripheral vascular diseases
0.001 0.999 0.001
I73.1 Thromboangiitis obliterans [Buerger]
0.001 0.999 0.001
I73.0 Raynaud's syndrome
0.001 0.999 0.001
I74.9 Embolism and thrombosis of unspecified artery
0.001 0.999 0.001
I74.8 Embolism and thrombosis of other arteries
0.001 0.999 0.001
I74.5 Embolism and thrombosis of iliac artery
0.001 0.999 0.001
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.001 0.999 0.001
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.001 0.999 0.001
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.001 0.999 0.001
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.001 0.999 0.001
I74.0 Embolism and thrombosis of abdominal aorta
0.001 0.999 0.001
I77.9 Disorder of arteries and arterioles, unspecified
0.001 0.999 0.001
I77.8 Other specified disorders of arteries and arterioles
0.001 0.999 0.001
I77.6 Arteritis, unspecified
0.001 0.999 0.001
I77.5 Necrosis of artery
0.001 0.999 0.001
I77.4 Coeliac artery compression syndrome
0.001 0.999 0.001
I77.3 Arterial fibromuscular dysplasia
0.001 0.999 0.001
I77.2 Rupture of artery
0.001 0.999 0.001
I77.1 Stricture of artery
0.001 0.999 0.001
I77.0 Arteriovenous fistula, acquired
0.001 0.999 0.001
I78.9 Disease of capillaries, unspecified
0.001 0.999 0.001
I78.8 Other diseases of capillaries
0.001 0.999 0.001
I78.1 Naevus, nonneoplastic
0.001 0.999 0.001
I78.0 Hereditary haemorrhagic telangiectasia
0.001 0.999 0.001
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.001 0.999 0.001
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.001 0.999 0.001
I79.1 Aortitis in diseases classified elsewhere
0.001 0.999 0.001
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.001 0.999 0.001
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.001 0.999 0.001
I80.8 Phlebitis and thrombophlebitis of other sites
0.001 0.999 0.001
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.001 0.999 0.001
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.001 0.999 0.001
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.001 0.999 0.001
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.001 0.999 0.001
I82.9 Embolism and thrombosis of unspecified vein
0.001 0.999 0.001
I82.8 Embolism and thrombosis of other specified veins
0.001 0.999 0.001
I82.3 Embolism and thrombosis of renal vein
0.001 0.999 0.001
I82.2 Embolism and thrombosis of vena cava
0.001 0.999 0.001
I82.1 Thrombophlebitis migrans
0.001 0.999 0.001
I82.0 Budd-Chiari syndrome
0.001 0.999 0.001
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.001 0.999 0.001
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.001 0.999 0.001
I83.1 Varicose veins of lower extremities with inflammation
0.001 0.999 0.001
I83.0 Varicose veins of lower extremities with ulcer
0.001 0.999 0.001
I84.9 Unspecified haemorrhoids without complication
0.001 0.999 0.001
I84.8 Unspecified haemorrhoids with other complications
0.001 0.999 0.001
I84.7 Unspecified thrombosed haemorrhoids
0.001 0.999 0.001
I84.6 Residual haemorrhoidal skin tags
0.001 0.999 0.001
I84.5 External haemorrhoids without complication
0.001 0.999 0.001
I84.4 External haemorrhoids with other complications
0.001 0.999 0.001
I84.3 External thrombosed haemorrhoids
0.001 0.999 0.001
I84.2 Internal haemorrhoids without complication
0.001 0.999 0.001
I84.1 Internal haemorrhoids with other complications
0.001 0.999 0.001
I84.0 Internal thrombosed haemorrhoids
0.001 0.999 0.001
I85.9 Oesophageal varices without bleeding
0.001 0.999 0.001
I85.0 Oesophageal varices with bleeding
0.001 0.999 0.001
I86.8 Varicose veins of other specified sites
0.001 0.999 0.001
I86.4 Gastric varices
0.001 0.999 0.001
I86.3 Vulval varices
0.001 0.999 0.001
I86.2 Pelvic varices
0.001 0.999 0.001
I86.1 Scrotal varices
0.001 0.999 0.001
I86.0 Sublingual varices
0.001 0.999 0.001
I87.9 Disorder of vein, unspecified
0.001 0.999 0.001
I87.8 Other specified disorders of veins
0.001 0.999 0.001
I87.2 Venous insufficiency (chronic) (peripheral)
0.001 0.999 0.001
I87.1 Compression of vein
0.001 0.999 0.001
I87.0 Postphlebitic syndrome
0.001 0.999 0.001
I88.9 Nonspecific lymphadenitis, unspecified
0.001 0.999 0.001
I88.8 Other nonspecific lymphadenitis
0.001 0.999 0.001
I88.1 Chronic lymphadenitis, except mesenteric
0.001 0.999 0.001
I88.0 Nonspecific mesenteric lymphadenitis
0.001 0.999 0.001
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.001 0.999 0.001
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.001 0.999 0.001
I89.1 Lymphangitis
0.001 0.999 0.001
I89.0 Lymphoedema, not elsewhere classified
0.001 0.999 0.001
I95.9 Hypotension, unspecified
0.001 0.999 0.001
I95.8 Other hypotension
0.001 0.999 0.001
I95.2 Hypotension due to drugs
0.001 0.999 0.001
I95.1 Orthostatic hypotension
0.001 0.999 0.001
I95.0 Idiopathic hypotension
0.001 0.999 0.001
I97.9 Postprocedural disorder of circulatory system, unspecified
0.001 0.999 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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