TreeWAS – Variant ID: rs1465537

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	0.983	0.017	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.982	0.018	0.000
I20-I25 Ischaemic heart diseases	0.973	0.027	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.951	0.049	0.000
I20 Angina pectoris	0.945	0.055	0.000
I20.0 Unstable angina	0.932	0.068	0.000
I25.1 Atherosclerotic heart disease	0.895	0.105	0.000
I24 Other acute ischaemic heart diseases	0.851	0.149	0.000
I10-I15 Hypertensive diseases	0.822	0.178	0.000
I21 Acute myocardial infarction	0.815	0.185	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.796	0.204	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.791	0.209	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.769	0.231	0.000
I20.9 Angina pectoris, unspecified	0.757	0.243	0.000
I20.1 Angina pectoris with documented spasm	0.754	0.246	0.000
Chapter IX Diseases of the circulatory system	0.751	0.249	0.000
I25.6 Silent myocardial ischaemia	0.705	0.295	0.000
I25.4 Coronary artery aneurysm	0.701	0.298	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.690	0.310	0.000
I25.5 Ischaemic cardiomyopathy	0.674	0.326	0.000
I23 Certain current complications following acute myocardial infarction	0.670	0.330	0.000
I11 Hypertensive heart disease	0.669	0.331	0.000
I25.2 Old myocardial infarction	0.665	0.335	0.000
I21.4 Acute subendocardial myocardial infarction	0.654	0.346	0.000
I22 Subsequent myocardial infarction	0.649	0.351	0.000
I24.1 Dressler's syndrome	0.610	0.389	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.590	0.410	0.000
I13 Hypertensive heart and renal disease	0.589	0.410	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.585	0.415	0.000
I15 Secondary hypertension	0.576	0.424	0.000
I25.3 Aneurysm of heart	0.571	0.429	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.563	0.437	0.000
I22.8 Subsequent myocardial infarction of other sites	0.549	0.451	0.000
I00-I02 Acute rheumatic fever	0.538	0.461	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.528	0.472	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.521	0.479	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.517	0.483	0.000
I05-I09 Chronic rheumatic heart diseases	0.493	0.507	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.480	0.520	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.480	0.520	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.480	0.520	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.480	0.520	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.480	0.520	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.480	0.520	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.480	0.520	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.454	0.546	0.000
I23.8 Other current complications following acute myocardial infarction	0.453	0.547	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.423	0.577	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.423	0.577	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.423	0.577	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.423	0.577	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.416	0.584	0.000
I15.9 Seconday hypertension, unspecified	0.413	0.587	0.000
I15.8 Other secondary hypertension	0.413	0.587	0.000
I15.2 Hypertension secondary to endocrine disorders	0.413	0.587	0.000
I15.0 Renovascular hypertension	0.413	0.587	0.000
I05 Rheumatic mitral valve diseases	0.411	0.589	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.409	0.591	0.000
I15.1 Hypertension secondary to other renal disorders	0.399	0.601	0.000
I02 Rheumatic chorea	0.386	0.614	0.000
I01 Rheumatic fever with heart involvement	0.386	0.614	0.000
I00 Rheumatic fever without mention of heart involvement	0.386	0.614	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.385	0.615	0.000
I06 Rheumatic aortic valve diseases	0.368	0.632	0.000
I09 Other rheumatic heart diseases	0.363	0.636	0.000
I05.1 Rheumatic mitral insufficiency	0.357	0.643	0.000
I07 Rheumatic tricuspid valve diseases	0.350	0.650	0.000
I24.8 Other forms of acute ischaemic heart disease	0.334	0.666	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.322	0.678	0.000
I05.9 Mitral valve disease, unspecified	0.319	0.681	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.316	0.684	0.000
I05.8 Other mitral valve diseases	0.295	0.705	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.293	0.706	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.293	0.706	0.000
I98.0 Cardiovascular syphilis	0.293	0.706	0.000
I05.2 Mitral stenosis with insufficiency	0.285	0.714	0.000
I06.0 Rheumatic aortic stenosis	0.278	0.721	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.277	0.723	0.000
I01.8 Other acute rheumatic heart disease	0.277	0.723	0.000
I01.2 Acute rheumatic myocarditis	0.277	0.723	0.000
I01.1 Acute rheumatic endocarditis	0.277	0.723	0.000
I01.0 Acute rheumatic pericarditis	0.277	0.723	0.000
I02.9 Rheumatic chorea without heart involvement	0.277	0.723	0.000
I02.0 Rheumatic chorea with heart involvement	0.277	0.723	0.000
I09.9 Rheumatic heart disease, unspecified	0.271	0.729	0.000
I05.0 Mitral stenosis	0.265	0.735	0.000
I97.1 Other functional disturbances following cardiac surgery	0.264	0.736	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.264	0.736	0.000
I06.8 Other rheumatic aortic valve diseases	0.264	0.736	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.264	0.736	0.000
I06.1 Rheumatic aortic insufficiency	0.264	0.736	0.000
I09.8 Other specified rheumatic heart diseases	0.261	0.739	0.000
I09.2 Chronic rheumatic pericarditis	0.261	0.739	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.261	0.739	0.000
I09.0 Rheumatic myocarditis	0.261	0.739	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.258	0.742	0.000
I07.9 Tricuspid valve disease, unspecified	0.251	0.749	0.000
I07.8 Other tricuspid valve diseases	0.251	0.749	0.000
I07.2 Tricuspid stenosis with insufficiency	0.251	0.749	0.000
I07.0 Tricuspid stenosis	0.251	0.749	0.000
I07.1 Tricuspid insufficiency	0.248	0.752	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.231	0.769	0.000
I97.0 Postcardiotomy syndrome	0.231	0.769	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.230	0.770	0.000
I12 Hypertensive renal disease	0.225	0.775	0.000
I60-I69 Cerebrovascular diseases	0.217	0.783	0.000
I28 Other diseases of pulmonary vessels	0.216	0.783	0.000
I20.8 Other forms of angina pectoris	0.201	0.799	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.197	0.803	0.000
I69 Sequelae of cerebrovascular disease	0.197	0.803	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.188	0.812	0.000
I27 Other pulmonary heart diseases	0.185	0.815	0.000
I95 Hypotension	0.181	0.819	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.180	0.820	0.000
I65.2 Occlusion and stenosis of carotid artery	0.180	0.820	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.179	0.821	0.000
I99 Other and unspecified disorders of circulatory system	0.178	0.821	0.001
I97.2 Postmastectomy lymphoedema syndrome	0.173	0.826	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.167	0.833	0.000
I21.9 Acute myocardial infarction, unspecified	0.165	0.835	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.165	0.835	0.000
I27.0 Primary pulmonary hypertension	0.160	0.840	0.000
I69.3 Sequelae of cerebral infarction	0.159	0.841	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.156	0.844	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.155	0.844	0.000
I28.1 Aneurysm of pulmonary artery	0.155	0.844	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.155	0.844	0.000
I95.1 Orthostatic hypotension	0.153	0.847	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.151	0.849	0.000
I28.8 Other specified diseases of pulmonary vessels	0.145	0.854	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.142	0.858	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.142	0.858	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.142	0.858	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.142	0.858	0.000
I65.1 Occlusion and stenosis of basilar artery	0.142	0.858	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.135	0.865	0.000
I27.1 Kyphoscoliotic heart disease	0.133	0.867	0.000
I95.0 Idiopathic hypotension	0.132	0.868	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.128	0.871	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.128	0.871	0.000
I62 Other nontraumatic intracranial haemorrhage	0.127	0.873	0.000
I63 Cerebral infarction	0.125	0.875	0.000
I08 Multiple valve diseases	0.124	0.876	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.124	0.876	0.000
I26 Pulmonary embolism	0.123	0.877	0.000
I27.8 Other specified pulmonary heart diseases	0.123	0.877	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.120	0.880	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.120	0.880	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.120	0.880	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.120	0.880	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.120	0.880	0.000
I72 Other aneurysm	0.117	0.883	0.000
I95.2 Hypotension due to drugs	0.115	0.885	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.112	0.888	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.112	0.888	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.112	0.888	0.000
I68.0 Cerebral amyloid angiopathy	0.112	0.888	0.000
I61 Intracerebral haemorrhage	0.110	0.890	0.000
I72.8 Aneurysm of other specified arteries	0.109	0.891	0.000
I27.9 Pulmonary heart disease, unspecified	0.101	0.899	0.000
I08.9 Multiple valve disease, unspecified	0.101	0.899	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.100	0.899	0.000
I95.8 Other hypotension	0.099	0.901	0.000
I72.1 Aneurysm of artery of upper extremity	0.095	0.905	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.094	0.906	0.000
I78 Diseases of capillaries	0.094	0.906	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.094	0.906	0.000
I08.8 Other multiple valve diseases	0.092	0.908	0.000
I61.8 Other intracerebral haemorrhage	0.091	0.909	0.000
I62.1 Nontraumatic extradural haemorrhage	0.091	0.909	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.090	0.910	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.090	0.910	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.090	0.910	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.090	0.910	0.000
I72.9 Aneurysm of unspecified site	0.088	0.912	0.000
I72.2 Aneurysm of renal artery	0.087	0.912	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.087	0.913	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.086	0.913	0.000
I72.3 Aneurysm of iliac artery	0.085	0.915	0.000
I27.2 Other secondary pulmonary hypertension	0.085	0.915	0.000
I63.8 Other cerebral infarction	0.084	0.916	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.084	0.916	0.000
I74 Arterial embolism and thrombosis	0.084	0.916	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.084	0.916	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.084	0.916	0.000
I63.9 Cerebral infarction, unspecified	0.082	0.918	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.078	0.922	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.078	0.922	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.078	0.922	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.075	0.925	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.074	0.926	0.000
I12.9 Hypertensive renal disease without renal failure	0.072	0.927	0.001
I61.4 Intracerebral haemorrhage in cerebellum	0.073	0.927	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.072	0.928	0.000
I79.1 Aortitis in diseases classified elsewhere	0.072	0.928	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.072	0.928	0.000
O36.8 Maternal care for other specified foetal problems	0.000	0.928	0.072
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.070	0.930	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.069	0.930	0.000
O36 Maternal care for other known or suspected foetal problems	0.000	0.931	0.069
I60 Subarachnoid haemorrhage	0.069	0.931	0.000
I08.0 Disorders of both mitral and aortic valves	0.068	0.932	0.000
I78.8 Other diseases of capillaries	0.068	0.932	0.000
I78.9 Disease of capillaries, unspecified	0.067	0.932	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.066	0.933	0.000
I78.1 Naevus, nonneoplastic	0.066	0.934	0.000
I70 Atherosclerosis	0.066	0.934	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.066	0.934	0.000
I73 Other peripheral vascular diseases	0.065	0.935	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.065	0.935	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.065	0.935	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.065	0.935	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.064	0.936	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.064	0.936	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.064	0.936	0.000
O36.4 Maternal care for intra-uterine death	0.000	0.938	0.062
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.062	0.938	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.061	0.938	0.000
I72.4 Aneurysm of artery of lower extremity	0.061	0.939	0.000
I77 Other disorders of arteries and arterioles	0.061	0.939	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.060	0.940	0.000
O36.5 Maternal care for poor foetal growth	0.000	0.941	0.059
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.941	0.059
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.942	0.058
I74.8 Embolism and thrombosis of other arteries	0.057	0.943	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.056	0.944	0.000
O36.9 Maternal care for foetal problem, unspecified	0.000	0.945	0.055
I74.5 Embolism and thrombosis of iliac artery	0.054	0.945	0.000
I73.8 Other specified peripheral vascular diseases	0.054	0.946	0.000
O36.6 Maternal care for excessive foetal growth	0.000	0.948	0.052
I72.0 Aneurysm of carotid artery	0.051	0.948	0.000
I67 Other cerebrovascular diseases	0.051	0.949	0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.050	0.950	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.950	0.050
O36.2 Maternal care for hydrops foetalis	0.000	0.950	0.050
O36.1 Maternal care for other isoimmunisation	0.000	0.950	0.050
I60.5 Subarachnoid haemorrhage from vertebral artery	0.050	0.950	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.050	0.950	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.049	0.951	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.048	0.952	0.000
I77.2 Rupture of artery	0.048	0.952	0.000
I70.9 Generalised and unspecified atherosclerosis	0.047	0.952	0.000
I70.8 Atherosclerosis of other arteries	0.047	0.952	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.047	0.953	0.000
I77.8 Other specified disorders of arteries and arterioles	0.047	0.953	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.046	0.953	0.001
I70.1 Atherosclerosis of renal artery	0.046	0.953	0.000
I12.0 Hypertensive renal disease with renal failure	0.046	0.954	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.046	0.954	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.045	0.955	0.000
I77.5 Necrosis of artery	0.044	0.956	0.000
I77.4 Coeliac artery compression syndrome	0.044	0.956	0.000
I77.3 Arterial fibromuscular dysplasia	0.044	0.956	0.000
I77.0 Arteriovenous fistula, acquired	0.044	0.956	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.040	0.960	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.040	0.960	0.000
I67.8 Other specified cerebrovascular diseases	0.040	0.960	0.000
I73.0 Raynaud's syndrome	0.040	0.960	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.039	0.961	0.000
I70.0 Atherosclerosis of aorta	0.038	0.961	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.037	0.963	0.000
I67.5 Moyamoya disease	0.037	0.963	0.000
I67.4 Hypertensive encephalopathy	0.037	0.963	0.000
I67.3 Progressive vascular leukoencephalopathy	0.037	0.963	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.036	0.964	0.000
I60.8 Other subarachnoid haemorrhage	0.035	0.965	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.035	0.965	0.000
I77.6 Arteritis, unspecified	0.034	0.965	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.034	0.965	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.034	0.965	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.034	0.965	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.034	0.965	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.033	0.966	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.032	0.968	0.000
I71 Aortic aneurysm and dissection	0.032	0.968	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.031	0.968	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.031	0.969	0.000
I67.2 Cerebral atherosclerosis	0.029	0.971	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.028	0.972	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.027	0.972	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.026	0.974	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.023	0.977	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.023	0.977	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.023	0.977	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.023	0.977	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.023	0.977	0.000
I77.1 Stricture of artery	0.022	0.978	0.000
L05.9 Pilonidal cyst without abscess	0.000	0.980	0.020
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.019	0.981	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.018	0.981	0.001
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.018	0.982	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.016	0.983	0.000
J45.0 Predominantly allergic asthma	0.015	0.985	0.000
I71.0 Dissection of aorta [any part]	0.015	0.985	0.000
I67.1 Cerebral aneurysm, nonruptured	0.014	0.985	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.014	0.986	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.013	0.987	0.000
I67.9 Cerebrovascular disease, unspecified	0.011	0.989	0.000
I73.9 Peripheral vascular disease, unspecified	0.011	0.989	0.000
I44.0 Atrioventricular block, first degree	0.011	0.989	0.000
I44.3 Other and unspecified atrioventricular block	0.011	0.989	0.000
I44 Atrioventricular and left bundle-branch block	0.011	0.989	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.010	0.990	0.000
I30-I52 Other forms of heart disease	0.010	0.990	0.000
O04.9 Complete or unspecified, without complication	0.000	0.991	0.009
I44.2 Atrioventricular block, complete	0.009	0.991	0.000
I30 Acute pericarditis	0.008	0.992	0.000
I44.5 Left posterior fascicular block	0.008	0.992	0.000
I44.4 Left anterior fascicular block	0.008	0.992	0.000
I85 Oesophageal varices	0.008	0.992	0.000
I40 Acute myocarditis	0.008	0.992	0.000
I52 Other heart disorders in diseases classified elsewhere	0.007	0.992	0.000
I48 Atrial fibrillation and flutter	0.007	0.992	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.007	0.992	0.000
I41 Myocarditis in diseases classified elsewhere	0.007	0.992	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.007	0.992	0.000
I32 Pericarditis in diseases classified elsewhere	0.007	0.992	0.000
I30.1 Infective pericarditis	0.007	0.993	0.000
I49 Other cardiac arrhythmias	0.007	0.993	0.000
I49.4 Other and unspecified premature depolarisation	0.007	0.993	0.000
I36 Nonrheumatic tricuspid valve disorders	0.007	0.993	0.000
I44.6 Other and unspecified fascicular block	0.007	0.993	0.000
I85.0 Oesophageal varices with bleeding	0.007	0.993	0.000
I81 Portal vein thrombosis	0.007	0.993	0.000
I51 Complications and ill-defined descriptions of heart disease	0.007	0.993	0.000
I44.1 Atrioventricular block, second degree	0.007	0.993	0.000
I33 Acute and subacute endocarditis	0.007	0.993	0.000
I49.3 Ventricular premature depolarisation	0.007	0.993	0.000
I37 Pulmonary valve disorders	0.007	0.993	0.000
I82 Other venous embolism and thrombosis	0.007	0.993	0.000
L05 Pilonidal cyst	0.000	0.993	0.007
I51.6 Cardiovascular disease, unspecified	0.007	0.993	0.000
I88 Nonspecific lymphadenitis	0.006	0.993	0.000
I80 Phlebitis and thrombophlebitis	0.006	0.994	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.994	0.006
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.994	0.006
I87 Other disorders of veins	0.006	0.994	0.000
O44 Placenta praevia	0.000	0.994	0.006
I30.8 Other forms of acute pericarditis	0.006	0.994	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.006	0.994	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.006	0.994	0.000
J45 Asthma	0.006	0.994	0.000
O41.0 Oligohydramnios	0.000	0.994	0.006
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.006	0.994	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.994	0.006
I40.0 Infective myocarditis	0.006	0.994	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.006	0.994	0.000
O41 Other disorders of amniotic fluid and membranes	0.000	0.994	0.006
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.994	0.006
I40.9 Acute myocarditis, unspecified	0.006	0.994	0.000
I40.8 Other acute myocarditis	0.006	0.994	0.000
I40.1 Isolated myocarditis	0.006	0.994	0.000
I51.0 Cardiac septal defect, acquired	0.006	0.994	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.006	0.994	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.006	0.994	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.006	0.994	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.006	0.994	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.006	0.994	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.006	0.994	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.006	0.994	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.006	0.994	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.006	0.994	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.006	0.994	0.000
I48.4 Atypical atrial flutter	0.006	0.994	0.000
I48.3 Typical atrial flutter	0.006	0.994	0.000
I48.2 Chronic atrial fibrillation	0.006	0.994	0.000
I48.1 Persistent atrial fibrillation	0.006	0.994	0.000
I48.0 Paroxysmal atrial fibrillation	0.006	0.994	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.006	0.994	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.006	0.994	0.000
I49.2 Junctional premature depolarisation	0.006	0.994	0.000
O44.1 Placenta praevia with haemorrhage	0.000	0.994	0.006
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.005	0.994	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.005	0.994	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.005	0.994	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.005	0.994	0.000
I42 Cardiomyopathy	0.006	0.994	0.000
W44.0 Home	0.005	0.995	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.005	0.995	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.005	0.995	0.000
I82.3 Embolism and thrombosis of renal vein	0.005	0.995	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.005	0.995	0.000
I51.5 Myocardial degeneration	0.005	0.995	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.005	0.995	0.000
I51.8 Other ill-defined heart diseases	0.005	0.995	0.000
I33.9 Acute endocarditis, unspecified	0.005	0.995	0.000
I34 Nonrheumatic mitral valve disorders	0.005	0.995	0.000
I87.9 Disorder of vein, unspecified	0.005	0.995	0.000
O33 Maternal care for known or suspected disproportion	0.000	0.995	0.005
I82.1 Thrombophlebitis migrans	0.005	0.995	0.000
I82.0 Budd-Chiari syndrome	0.005	0.995	0.000
I37.9 Pulmonary valve disorder, unspecified	0.005	0.995	0.000
I37.8 Other pulmonary valve disorders	0.005	0.995	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.005	0.995	0.000
I37.0 Pulmonary valve stenosis	0.005	0.995	0.000
I30.9 Acute pericarditis, unspecified	0.005	0.995	0.000
Chapter XX External causes of morbidity and mortality	0.005	0.995	0.000
J45.1 Nonallergic asthma	0.005	0.995	0.000
I88.8 Other nonspecific lymphadenitis	0.005	0.995	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.005	0.995	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.005	0.995	0.000
I45.6 Preexcitation syndrome	0.005	0.995	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.005	0.995	0.000
I49.9 Cardiac arrhythmia, unspecified	0.005	0.995	0.000
W44 Foreign body entering into or through eye or natural orifice	0.005	0.995	0.000
O31 Complications specific to multiple gestation	0.000	0.995	0.005
I87.1 Compression of vein	0.005	0.995	0.000
I87.0 Postphlebitic syndrome	0.005	0.995	0.000
Y84.8 Other medical procedures	0.005	0.995	0.000
I49.1 Atrial premature depolarisation	0.005	0.995	0.000
O45 Premature separation of placenta [abruptio placentae]	0.000	0.995	0.005
J45.8 Mixed asthma	0.005	0.995	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.005	0.995	0.000
I46 Cardiac arrest	0.005	0.995	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.005	0.995	0.000
I51.7 Cardiomegaly	0.005	0.995	0.000
I45 Other conduction disorders	0.005	0.995	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.005	0.995	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.995	0.005
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.995	0.005
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.995	0.005
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.995	0.005
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.995	0.005
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.995	0.005
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.995	0.005
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.995	0.004
O41.1 Infection of amniotic sac and membranes	0.000	0.995	0.004
I42.8 Other cardiomyopathies	0.005	0.995	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.005	0.995	0.000
W00-W19 Falls	0.005	0.995	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.995	0.004
I33.0 Acute and subacute infective endocarditis	0.004	0.995	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.004	0.995	0.000
X60-X84 Intentional self-harm	0.004	0.995	0.000
W20-W49 Exposure to inanimate mechanical forces	0.004	0.995	0.000
I82.8 Embolism and thrombosis of other specified veins	0.004	0.995	0.000
I49.8 Other specified cardiac arrhythmias	0.004	0.996	0.000
Y84.0 Cardiac catheterisation	0.004	0.996	0.000
I51.4 Myocarditis, unspecified	0.004	0.996	0.000
W07 Fall involving chair	0.004	0.996	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.004	0.996	0.000
I42.2 Other hypertrophic cardiomyopathy	0.004	0.996	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.004	0.996	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.004	0.996	0.000
I82.2 Embolism and thrombosis of vena cava	0.004	0.996	0.000
I38 Endocarditis, valve unspecified	0.004	0.996	0.000
I42.9 Cardiomyopathy, unspecified	0.004	0.996	0.000
J47 Bronchiectasis	0.004	0.996	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.004	0.996	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.996	0.004
I42.7 Cardiomyopathy due to drugs and other external agents	0.004	0.996	0.000
I42.5 Other restrictive cardiomyopathy	0.004	0.996	0.000
I42.4 Endocardial fibroelastosis	0.004	0.996	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.004	0.996	0.000
W18 Other fall on same level	0.004	0.996	0.000
I49.5 Sick sinus syndrome	0.004	0.996	0.000
O33.9 Maternal care for disproportion, unspecified	0.000	0.996	0.004
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.004	0.996	0.000
O04 Medical abortion	0.000	0.996	0.004
O40 Polyhydramnios	0.000	0.996	0.004
W14 Fall from tree	0.004	0.996	0.000
X47 Accidental poisoning by and exposure to other gases and vapours	0.004	0.996	0.000
X20-X29 Contact with venomous animals and plants	0.004	0.996	0.000
V01-V09 Pedestrian injured in transport accident	0.004	0.996	0.000
W07.9 Unspecified place	0.004	0.996	0.000
I37.1 Pulmonary valve insufficiency	0.004	0.996	0.000
Y00-Y09 Assault	0.004	0.996	0.000
V80-V89 Other land transport accidents	0.004	0.996	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.996	0.004
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.004	0.996	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.996	0.004
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.004	0.996	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.004	0.996	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.004	0.996	0.000
R05 Cough	0.004	0.996	0.000
I44.7 Left bundle-branch block, unspecified	0.004	0.996	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.004	0.996	0.000
R19.5 Other fecal abnormalities	0.004	0.996	0.000
W50-W64 Exposure to animate mechanical forces	0.004	0.996	0.000
I49.0 Ventricular fibrillation and flutter	0.004	0.996	0.000
O30 Multiple gestation	0.000	0.996	0.004
I80.8 Phlebitis and thrombophlebitis of other sites	0.004	0.996	0.000
Y87.1 Sequelae of assault	0.004	0.996	0.000
W10 Fall on and from stairs and steps	0.004	0.996	0.000
J40-J47 Chronic lower respiratory diseases	0.004	0.996	0.000
W18.5 Trade and service area	0.004	0.996	0.000
I86 Varicose veins of other sites	0.004	0.996	0.000
O33.8 Maternal care for disproportion of other origin	0.000	0.996	0.004
O33.7 Maternal care for disproportion due to other foetal deformities	0.000	0.996	0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations