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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs146733600
log Bayes Factor = 68.4232
Chromosome 6   position 32,573,760  (GRCh37) Explore rs146733600 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
1.000 0.000 0.000
E11.9 Without complications
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
0.999 0.001 0.000
E10.1 With ketoacidosis
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.999 0.001 0.000
H30-H36 Disorders of choroid and retina
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
E16 Other disorders of pancreatic internal secretion
0.999 0.001 0.000
E16.2 Hypoglycaemia, unspecified
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.998 0.002 0.000
E11.3 With ophthalmic complications
0.997 0.003 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.997 0.003 0.000
E14 Unspecified diabetes mellitus
0.993 0.007 0.000
I73 Other peripheral vascular diseases
0.991 0.009 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.988 0.012 0.000
E10.4 With neurological complications
0.988 0.012 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.986 0.014 0.000
J40-J47 Chronic lower respiratory diseases
0.985 0.015 0.000
I73.9 Peripheral vascular disease, unspecified
0.984 0.016 0.000
Chapter V Mental and behavioural disorders
0.983 0.017 0.000
J30-J39 Other diseases of upper respiratory tract
0.981 0.019 0.000
J45 Asthma
0.979 0.021 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.977 0.023 0.000
D50-D53 Nutritional anaemias
0.975 0.025 0.000
J45.9 Asthma, unspecified
0.974 0.026 0.000
E14.9 Without complications
0.962 0.038 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.960 0.040 0.000
D50 Iron deficiency anaemia
0.955 0.045 0.000
E14.3 With ophthalmic complications
0.952 0.048 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.948 0.052 0.000
E10.5 With peripheral circulatory complications
0.943 0.057 0.000
J33 Nasal polyp
0.941 0.059 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.940 0.060 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.938 0.062 0.000
S60-S69 Injuries to the wrist and hand
0.938 0.062 0.000
E70-E90 Metabolic disorders
0.937 0.063 0.000
D60-D64 Aplastic and other anaemias
0.934 0.066 0.000
J09-J18 Influenza and pneumonia
0.927 0.073 0.000
D50.9 Iron deficiency anaemia, unspecified
0.926 0.074 0.000
S40-S49 Injuries to the shoulder and upper arm
0.924 0.076 0.000
J90-J94 Other diseases of pleura
0.924 0.076 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.921 0.079 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.920 0.080 0.000
E11.4 With neurological complications
0.914 0.086 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.913 0.087 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.910 0.090 0.000
J33.9 Nasal polyp, unspecified
0.906 0.094 0.000
Chapter VI Diseases of the nervous system
0.904 0.096 0.000
S20-S29 Injuries to the thorax
0.898 0.102 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.897 0.103 0.000
L05 Pilonidal cyst
0.888 0.112 0.000
E10.2 With renal complications
0.888 0.112 0.000
S70-S79 Injuries to the hip and thigh
0.882 0.118 0.000
D64 Other anaemias
0.878 0.122 0.000
I70 Atherosclerosis
0.876 0.124 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.876 0.124 0.000
E87.2 Acidosis
0.874 0.126 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.872 0.128 0.000
I77 Other disorders of arteries and arterioles
0.871 0.129 0.000
E11.1 With ketoacidosis
0.870 0.130 0.000
I74 Arterial embolism and thrombosis
0.868 0.132 0.000
F10.2 Dependence syndrome
0.864 0.136 0.000
H35 Other retinal disorders
0.860 0.140 0.000
O60-O75 Complications of labour and delivery
0.857 0.143 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.856 0.144 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.854 0.146 0.000
M65-M68 Disorders of synovium and tendon
0.852 0.148 0.000
S42 Fracture of shoulder and upper arm
0.851 0.149 0.000
J18 Pneumonia, organism unspecified
0.851 0.149 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.849 0.151 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.848 0.152 0.000
E11.5 With peripheral circulatory complications
0.848 0.152 0.000
D51 Vitamin B12 deficiency anaemia
0.846 0.154 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.844 0.155 0.000
J32 Chronic sinusitis
0.844 0.156 0.000
L91 Hypertrophic disorders of skin
0.840 0.160 0.000
E11.6 With other specified complications
0.839 0.161 0.000
E10.6 With other specified complications
0.839 0.161 0.000
D64.9 Anaemia, unspecified
0.837 0.163 0.000
E10.0 With coma
0.837 0.163 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.836 0.164 0.000
D50.8 Other iron deficiency anaemias
0.834 0.166 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.831 0.169 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.828 0.172 0.000
F10.1 Harmful use
0.827 0.173 0.000
L08 Other local infections of skin and subcutaneous tissue
0.826 0.174 0.000
E86 Volume depletion
0.825 0.175 0.000
M13 Other arthritis
0.822 0.178 0.000
S80-S89 Injuries to the knee and lower leg
0.820 0.180 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.820 0.180 0.000
H55-H59 Other disorders of eye and adnexa
0.819 0.181 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.812 0.188 0.000
Chapter I Certain infectious and parasitic diseases
0.810 0.190 0.000
L03 Cellulitis
0.810 0.190 0.000
S62 Fracture at wrist and hand level
0.807 0.193 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.802 0.198 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.795 0.205 0.000
H53-H54 Visual disturbances and blindness
0.794 0.206 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.794 0.206 0.000
L05.9 Pilonidal cyst without abscess
0.793 0.207 0.000
Chapter VIII Diseases of the ear and mastoid process
0.793 0.207 0.000
M14 Arthropathies in other diseases classified elsewhere
0.791 0.209 0.000
J90 Pleural effusion, not elsewhere classified
0.791 0.209 0.000
I73.0 Raynaud's syndrome
0.790 0.210 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.789 0.211 0.000
M45-M49 Spondylopathies
0.789 0.211 0.000
G63.2 Diabetic polyneuropathy
0.788 0.212 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.786 0.214 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.784 0.216 0.000
E87.7 Fluid overload
0.782 0.218 0.000
O16 Unspecified maternal hypertension
0.781 0.219 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.780 0.220 0.000
M05 Seropositive rheumatoid arthritis
0.780 0.220 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.778 0.222 0.000
L40-L45 Papulosquamous disorders
0.777 0.223 0.000
M06.0 Seronegative rheumatoid arthritis
0.777 0.223 0.000
I72 Other aneurysm
0.776 0.224 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.774 0.226 0.000
S72 Fracture of femur
0.774 0.226 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.774 0.226 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.771 0.229 0.000
O80-O84 Delivery
0.769 0.231 0.000
J18.1 Lobar pneumonia, unspecified
0.767 0.233 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.766 0.234 0.000
E11.2 With renal complications
0.765 0.235 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.765 0.235 0.000
S40 Superficial injury of shoulder and upper arm
0.763 0.237 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.763 0.237 0.000
O72 Postpartum haemorrhage
0.762 0.238 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.760 0.240 0.000
I78 Diseases of capillaries
0.760 0.240 0.000
E87.5 Hyperkalaemia
0.760 0.240 0.000
M15-M19 Arthrosis
0.760 0.240 0.000
B95-B98 Bacterial, viral and other infectious agents
0.760 0.240 0.000
M65 Synovitis and tenosynovitis
0.759 0.241 0.000
J42 Unspecified chronic bronchitis
0.759 0.241 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.758 0.242 0.000
O36 Maternal care for other known or suspected foetal problems
0.757 0.243 0.000
J93 Pneumothorax
0.757 0.243 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.757 0.243 0.000
G90-G99 Other disorders of the nervous system
0.756 0.244 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.756 0.244 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.756 0.244 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.754 0.246 0.000
L50-L54 Urticaria and erythema
0.754 0.246 0.000
E50-E64 Other nutritional deficiencies
0.751 0.249 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.751 0.249 0.000
S42.1 Fracture of scapula
0.750 0.250 0.000
S64 Injury of nerves at wrist and hand level
0.750 0.250 0.000
E40-E46 Malnutrition
0.750 0.250 0.000
S27 Injury of other and unspecified intrathoracic organs
0.749 0.251 0.000
L91.8 Other hypertrophic disorders of skin
0.748 0.252 0.000
S42.2 Fracture of upper end of humerus
0.747 0.253 0.000
I77.6 Arteritis, unspecified
0.746 0.254 0.000
H43-H45 Disorders of vitreous body and globe
0.746 0.254 0.000
M07 Psoriatic and enteropathic arthropathies
0.746 0.254 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.746 0.254 0.000
I99 Other and unspecified disorders of circulatory system
0.745 0.255 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.745 0.255 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.744 0.255 0.000
Chapter XXII Codes for special purposes
0.744 0.256 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.743 0.257 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.743 0.257 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.743 0.257 0.000
E00-E07 Disorders of thyroid gland
0.742 0.258 0.000
M91-M94 Chondropathies
0.741 0.258 0.000
J39 Other diseases of upper respiratory tract
0.740 0.260 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.739 0.261 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.739 0.261 0.000
F03 Unspecified dementia
0.738 0.261 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.738 0.262 0.000
J95-J99 Other diseases of the respiratory system
0.737 0.263 0.000
H35.9 Retinal disorder, unspecified
0.737 0.263 0.000
J45.0 Predominantly allergic asthma
0.737 0.263 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.736 0.264 0.000
H54 Blindness and low vision
0.736 0.264 0.000
F60-F69 Disorders of adult personality and behaviour
0.736 0.264 0.000
S50-S59 Injuries to the elbow and forearm
0.736 0.264 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.735 0.265 0.000
J94 Other pleural conditions
0.734 0.266 0.000
I10-I15 Hypertensive diseases
0.733 0.267 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.731 0.269 0.000
M40-M43 Deforming dorsopathies
0.730 0.270 0.000
J46 Status asthmaticus
0.730 0.270 0.000
I60-I69 Cerebrovascular diseases
0.730 0.270 0.000
M18 Arthrosis of first carpometacarpal joint
0.730 0.270 0.000
E13 Other specified diabetes mellitus
0.729 0.271 0.000
S90-S99 Injuries to the ankle and foot
0.728 0.271 0.000
J91 Pleural effusion in conditions classified elsewhere
0.728 0.272 0.000
T66-T78 Other and unspecified effects of external causes
0.726 0.274 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.726 0.274 0.000
L89 Decubitus ulcer
0.723 0.277 0.000
S62.6 Fracture of other finger
0.722 0.278 0.000
S69 Other and unspecified injuries of wrist and hand
0.719 0.280 0.000
J31.0 Chronic rhinitis
0.719 0.281 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.718 0.282 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.718 0.282 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.717 0.283 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.717 0.283 0.000
E10.8 With unspecified complications
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E11.8 With unspecified complications
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E11.0 With coma
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.4 Inflammatory polyarthropathy
0.717 0.283 0.000
M06.3 Rheumatoid nodule
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.716 0.284 0.000
H31 Other disorders of choroid
0.716 0.284 0.000
H30 Chorioretinal inflammation
0.716 0.284 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.716 0.284 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.716 0.284 0.000
E16.4 Abnormal secretion of gastrin
0.716 0.284 0.000
E16.3 Increased secretion of glucagon
0.716 0.284 0.000
E16.1 Other hypoglycaemia
0.716 0.284 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
J32.2 Chronic ethmoidal sinusitis
0.715 0.285 0.000
L10-L14 Bullous disorders
0.715 0.285 0.000
G59.0 Diabetic mononeuropathy
0.715 0.285 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.713 0.287 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.713 0.287 0.000
F01 Vascular dementia
0.712 0.288 0.000
E14.8 With unspecified complications
0.712 0.288 0.000
E14.7 With multiple complications
0.712 0.288 0.000
E14.6 With other specified complications
0.712 0.288 0.000
E14.5 With peripheral circulatory complications
0.712 0.288 0.000
E14.4 With neurological complications
0.712 0.288 0.000
E14.2 Withrenal complications
0.712 0.288 0.000
E14.1 With ketoacidosis
0.712 0.288 0.000
E14.0 With coma
0.712 0.288 0.000
F10.4 Withdrawal state with delirium
0.712 0.288 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.711 0.289 0.000
I73.8 Other specified peripheral vascular diseases
0.711 0.289 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.711 0.289 0.000
S60 Superficial injury of wrist and hand
0.710 0.290 0.000
M86-M90 Other osteopathies
0.710 0.290 0.000
D55-D59 Haemolytic anaemias
0.709 0.291 0.000
F80-F89 Disorders of psychological development
0.709 0.291 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.709 0.291 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.708 0.292 0.000
M11 Other crystal arthropathies
0.708 0.292 0.000
L04 Acute lymphadenitis
0.707 0.293 0.000
L01 Impetigo
0.707 0.293 0.000
L00 Staphylococcal scalded skin syndrome
0.707 0.293 0.000
J41 Simple and mucopurulent chronic bronchitis
0.706 0.294 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.705 0.295 0.000
J33.8 Other polyp of sinus
0.705 0.295 0.000
F99-F99 Unspecified mental disorder
0.704 0.295 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.704 0.295 0.000
F70-F79 Mental retardation
0.704 0.295 0.000
L05.0 Pilonidal cyst with abscess
0.704 0.296 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.704 0.296 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.704 0.296 0.000
J37 Chronic laryngitis and laryngotracheitis
0.703 0.296 0.000
D61 Other aplastic anaemias
0.703 0.297 0.000
J45.8 Mixed asthma
0.702 0.298 0.000
J45.1 Nonallergic asthma
0.702 0.298 0.000
D80-D89 Certain disorders involving the immune mechanism
0.701 0.299 0.000
O85-O92 Complications predominantly related to the puerperium
0.700 0.300 0.000
H10-H13 Disorders of conjunctiva
0.699 0.301 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.699 0.301 0.000
D53 Other nutritional anaemias
0.699 0.301 0.000
D52 Folate deficiency anaemia
0.699 0.301 0.000
J33.0 Polyp of nasal cavity
0.698 0.302 0.000
J30 Vasomotor and allergic rhinitis
0.697 0.303 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.696 0.304 0.000
M13.9 Arthritis, unspecified
0.695 0.305 0.000
M50-M54 Other dorsopathies
0.695 0.305 0.000
O72.1 Other immediate postpartum haemorrhage
0.694 0.306 0.000
M65.3 Trigger finger
0.694 0.306 0.000
S67 Crushing injury of wrist and hand
0.693 0.307 0.000
T79-T79 Certain early complications of trauma
0.692 0.308 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.689 0.311 0.000
F10.3 Withdrawal state
0.689 0.311 0.000
S79 Other and unspecified injuries of hip and thigh
0.689 0.311 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.688 0.311 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.688 0.311 0.000
L94 Other localised connective tissue disorders
0.688 0.311 0.000
L93 Lupus erythematosus
0.688 0.311 0.000
L87 Transepidermal elimination disorders
0.688 0.311 0.000
L88 Pyoderma gangrenosum
0.688 0.311 0.000
L86 Keratoderma in diseases classified elsewhere
0.688 0.311 0.000
L83 Acanthosis nigricans
0.688 0.311 0.000
L80 Vitiligo
0.688 0.311 0.000
J40 Bronchitis, not specified as acute or chronic
0.688 0.312 0.000
J18.0 Bronchopneumonia, unspecified
0.686 0.314 0.000
F10.0 Acute intoxication
0.686 0.314 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.686 0.314 0.000
J35 Chronic diseases of tonsils and adenoids
0.685 0.315 0.000
D50.1 Sideropenic dysphagia
0.685 0.315 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.684 0.316 0.000
I71 Aortic aneurysm and dissection
0.682 0.317 0.000
J60-J70 Lung diseases due to external agents
0.682 0.317 0.000
E88 Other metabolic disorders
0.682 0.318 0.000
I20-I25 Ischaemic heart diseases
0.681 0.319 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.681 0.319 0.000
I77.1 Stricture of artery
0.680 0.320 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.678 0.322 0.000
S42.10 Fracture of scapula (closed)
0.678 0.322 0.000
L03.3 Cellulitis of trunk
0.677 0.323 0.000
J47 Bronchiectasis
0.677 0.323 0.000
S83.2 Tear of meniscus, current
0.677 0.323 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.676 0.324 0.000
D62 Acute posthaemorrhagic anaemia
0.676 0.324 0.000
H34 Retinal vascular occlusions
0.676 0.324 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.675 0.325 0.000
J33.1 Polypoid sinus degeneration
0.675 0.325 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.674 0.326 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.674 0.326 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.674 0.326 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.674 0.326 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.674 0.326 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.674 0.326 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.674 0.326 0.000
F11 Mental and behavioural disorders due to use of opioids
0.674 0.326 0.000
H35.0 Background retinopathy and retinal vascular changes
0.674 0.326 0.000
S68 Traumatic amputation of wrist and hand
0.673 0.327 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.673 0.327 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.673 0.327 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.673 0.327 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.673 0.327 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.673 0.327 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.673 0.327 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.673 0.327 0.000
T36 Poisoning by systemic antibiotics
0.673 0.327 0.000
S65 Injury of blood vessels at wrist and hand level
0.673 0.327 0.000
E85 Amyloidosis
0.672 0.328 0.000
E84 Cystic fibrosis
0.672 0.328 0.000
E79 Disorders of purine and pyrimidine metabolism
0.672 0.328 0.000
E77 Disorders of glycoprotein metabolism
0.672 0.328 0.000
E76 Disorders of glycosaminoglycan metabolism
0.672 0.328 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.672 0.328 0.000
E74 Other disorders of carbohydrate metabolism
0.672 0.328 0.000
E73 Lactose intolerance
0.672 0.328 0.000
E72 Other disorders of amino-acid metabolism
0.672 0.328 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.672 0.328 0.000
E70 Disorders of aromatic amino-acid metabolism
0.672 0.328 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.672 0.328 0.000
H65-H75 Diseases of middle ear and mastoid
0.672 0.328 0.000
S42.20 Fracture of upper end of humerus (closed)
0.672 0.328 0.000
L90 Atrophic disorders of skin
0.671 0.329 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.670 0.330 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.669 0.330 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.666 0.334 0.000
J17 Pneumonia in diseases classified elsewhere
0.665 0.335 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.665 0.335 0.000
J12 Viral pneumonia, not elsewhere classified
0.665 0.335 0.000
J11 Influenza, virus not identified
0.665 0.335 0.000
J10 Influenza due to identified influenza virus
0.665 0.335 0.000
J14 Pneumonia due to Haemophilus influenzae
0.665 0.335 0.000
J09 Influenza due to certain identified influenza virus
0.665 0.335 0.000
O40 Polyhydramnios
0.665 0.335 0.000
H35.8 Other specified retinal disorders
0.663 0.337 0.000
S48 Traumatic amputation of shoulder and upper arm
0.663 0.337 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.663 0.337 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.663 0.337 0.000
S44 Injury of nerves at shoulder and upper arm level
0.663 0.337 0.000
S41 Open wound of shoulder and upper arm
0.663 0.337 0.000
S47 Crushing injury of shoulder and upper arm
0.663 0.337 0.000
O48 Prolonged pregnancy
0.662 0.338 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.662 0.338 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.662 0.338 0.000
S20 Superficial injury of thorax
0.662 0.338 0.000
F10.9 Unspecified mental and behavioural disorder
0.660 0.339 0.000
F10.8 Other mental and behavioural disorders
0.660 0.339 0.000
F10.7 Residual and late-onset psychotic disorder
0.660 0.339 0.000
F10.6 Amnesic syndrome
0.660 0.339 0.000
F10.5 Psychotic disorder
0.660 0.339 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.660 0.340 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.660 0.340 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.660 0.340 0.000
A30-A49 Other bacterial diseases
0.659 0.341 0.000
I74.5 Embolism and thrombosis of iliac artery
0.659 0.341 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.658 0.342 0.000
G54 Nerve root and plexus disorders
0.657 0.343 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.654 0.346 0.000
E87.4 Mixed disorder of acid-base balance
0.654 0.346 0.000
E87.3 Alkalosis
0.654 0.346 0.000
J36 Peritonsillar abscess
0.654 0.346 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.654 0.346 0.000
J84 Other interstitial pulmonary diseases
0.654 0.346 0.000
O62 Abnormalities of forces of labour
0.653 0.347 0.000
J43 Emphysema
0.652 0.348 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.650 0.350 0.000
S72.0 Fracture of neck of femur
0.649 0.350 0.000
L84 Corns and callosities
0.649 0.351 0.000
G70-G73 Diseases of myoneural junction and muscle
0.648 0.351 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.648 0.351 0.000
O43 Placental disorders
0.648 0.352 0.000
M65.34 Trigger finger-Hand
0.647 0.353 0.000
L03.8 Cellulitis of other sites
0.646 0.354 0.000
M10 Gout
0.645 0.355 0.000
S29 Other and unspecified injuries of thorax
0.644 0.356 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.644 0.356 0.000
S26 Injury of heart
0.644 0.356 0.000
S25 Injury of blood vessels of thorax
0.644 0.356 0.000
S24 Injury of nerves and spinal cord at thorax level
0.644 0.356 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.644 0.356 0.000
S21 Open wound of thorax
0.644 0.356 0.000
O15 Eclampsia
0.643 0.357 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.643 0.357 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.643 0.357 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.643 0.357 0.000
S27.0 Traumatic pneumothorax
0.643 0.357 0.000
M48 Other spondylopathies
0.642 0.358 0.000
M14.6 Neuropathic arthropathy
0.642 0.358 0.000
L81 Other disorders of pigmentation
0.640 0.359 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.640 0.360 0.000
J32.0 Chronic maxillary sinusitis
0.640 0.360 0.000
F45 Somatoform disorders
0.640 0.360 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.639 0.360 0.000
H54.0 Blindness, both eyes
0.639 0.361 0.000
O82 Single delivery by Caesarean section
0.639 0.361 0.000
S72.1 Pertrochanteric fracture
0.637 0.363 0.000
E89.3 Postprocedural hypopituitarism
0.636 0.364 0.000
S22.4 Multiple fractures of ribs
0.635 0.365 0.000
L20-L30 Dermatitis and eczema
0.635 0.365 0.000
G58 Other mononeuropathies
0.635 0.365 0.000
L03.2 Cellulitis of face
0.635 0.365 0.000
H55 Nystagmus and other irregular eye movements
0.635 0.365 0.000
L60-L75 Disorders of skin appendages
0.634 0.366 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.633 0.367 0.000
S78 Traumatic amputation of hip and thigh
0.632 0.367 0.000
S77 Crushing injury of hip and thigh
0.632 0.367 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.632 0.367 0.000
S75 Injury of blood vessels at hip and thigh level
0.632 0.367 0.000
S74 Injury of nerves at hip and thigh level
0.632 0.367 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.632 0.367 0.000
S71 Open wound of hip and thigh
0.632 0.367 0.000
S70 Superficial injury of hip and thigh
0.632 0.367 0.000
M80-M85 Disorders of bone density and structure
0.632 0.368 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.632 0.368 0.000
L03.0 Cellulitis of finger and toe
0.631 0.368 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.630 0.370 0.000
L40 Psoriasis
0.630 0.370 0.000
J93.9 Pneumothorax, unspecified
0.630 0.370 0.000
I15 Secondary hypertension
0.629 0.371 0.000
J32.9 Chronic sinusitis, unspecified
0.629 0.371 0.000
D64.8 Other specified anaemias
0.629 0.371 0.000
D64.4 Congenital dyserythropoietic anaemia
0.629 0.371 0.000
D64.3 Other sideroblastic anaemias
0.629 0.371 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.629 0.371 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.629 0.371 0.000
D64.0 Hereditary sideroblastic anaemia
0.629 0.371 0.000
H35.4 Peripheral retinal degeneration
0.629 0.371 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.629 0.371 0.000
F00 Dementia in Alzheimer's disease
0.628 0.371 0.000
I70.9 Generalised and unspecified atherosclerosis
0.628 0.372 0.000
I70.8 Atherosclerosis of other arteries
0.628 0.372 0.000
I70.1 Atherosclerosis of renal artery
0.628 0.372 0.000
I70.0 Atherosclerosis of aorta
0.628 0.372 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.628 0.372 0.000
F02 Dementia in other diseases classified elsewhere
0.628 0.372 0.000
F09 Unspecified organic or symptomatic mental disorder
0.628 0.372 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.628 0.372 0.000
L85 Other epidermal thickening
0.628 0.372 0.000
E61 Deficiency of other nutrient elements
0.626 0.374 0.000
J00-J06 Acute upper respiratory infections
0.625 0.375 0.000
I77.8 Other specified disorders of arteries and arterioles
0.625 0.375 0.000
I77.5 Necrosis of artery
0.625 0.375 0.000
I77.4 Coeliac artery compression syndrome
0.625 0.375 0.000
I77.3 Arterial fibromuscular dysplasia
0.625 0.375 0.000
I77.2 Rupture of artery
0.625 0.375 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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