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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs147786325
log Bayes Factor = 1.81622
Chromosome 3   position 70,725,902  (GRCh37) Explore rs147786325 on Ensembl!
Variant rs147786325 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.983 0.017 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.983 0.017 0.000
M50-M54 Other dorsopathies
0.975 0.025 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.967 0.033 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.958 0.042 0.000
M54 Dorsalgia
0.954 0.046 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.948 0.052 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.944 0.056 0.000
Chapter VII Diseases of the eye and adnexa
0.921 0.079 0.000
M45-M49 Spondylopathies
0.920 0.080 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.911 0.089 0.000
Chapter XXI Factors influencing health status and contact with health services
0.893 0.107 0.000
M50 Cervical disk disorders
0.891 0.109 0.000
S60-S69 Injuries to the wrist and hand
0.890 0.110 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.886 0.113 0.000
M47 Spondylosis
0.879 0.121 0.000
M54.3 Sciatica
0.874 0.126 0.000
E00-E07 Disorders of thyroid gland
0.872 0.128 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.863 0.137 0.000
M47.8 Other spondylosis
0.847 0.153 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.841 0.159 0.000
Chapter XXII Codes for special purposes
0.840 0.160 0.000
E20-E35 Disorders of other endocrine glands
0.833 0.167 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.825 0.175 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.819 0.181 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.817 0.183 0.000
M47.82 Other spondylosis (Cervical region)
0.813 0.187 0.000
M70-M79 Other soft tissue disorders
0.810 0.190 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.807 0.193 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.806 0.194 0.000
O00-O08 Pregnancy with abortive outcome
0.805 0.195 0.000
Chapter XIV Diseases of the genitourinary system
0.799 0.201 0.000
T86 Failure and rejection of transplanted organs and tissues
0.798 0.202 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.796 0.204 0.000
O80-O84 Delivery
0.794 0.206 0.000
Chapter V Mental and behavioural disorders
0.789 0.211 0.000
Chapter VI Diseases of the nervous system
0.789 0.211 0.000
M20-M25 Other joint disorders
0.784 0.216 0.000
N60-N64 Disorders of breast
0.782 0.218 0.000
M50.1 Cervical disk disorder with radiculopathy
0.782 0.218 0.000
M54.36 Sciatica (Lumbar region)
0.780 0.220 0.000
H30-H36 Disorders of choroid and retina
0.778 0.222 0.000
M54.1 Radiculopathy
0.774 0.226 0.000
M54.5 Low back pain
0.771 0.229 0.000
M86-M90 Other osteopathies
0.771 0.229 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.769 0.230 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.769 0.231 0.000
M54.6 Pain in thoracic spine
0.769 0.231 0.000
M54.2 Cervicalgia
0.769 0.231 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.768 0.232 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.762 0.238 0.000
H40-H42 Glaucoma
0.761 0.239 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.761 0.239 0.000
E03 Other hypothyroidism
0.756 0.244 0.000
Z48 Other surgical follow-up care
0.753 0.247 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.753 0.247 0.000
Z40 Prophylactic surgery
0.753 0.247 0.000
M00-M03 Infectious arthropathies
0.751 0.249 0.000
G56 Mononeuropathies of upper limb
0.748 0.252 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.747 0.253 0.000
M80-M85 Disorders of bone density and structure
0.745 0.255 0.000
Z53.9 Procedure not carried out, unspecified reason
0.745 0.255 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.744 0.256 0.000
M50.2 Other cervical disk displacement
0.743 0.257 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.743 0.257 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.740 0.260 0.000
G56.0 Carpal tunnel syndrome
0.740 0.260 0.000
S60 Superficial injury of wrist and hand
0.739 0.261 0.000
O60-O75 Complications of labour and delivery
0.736 0.264 0.000
H55-H59 Other disorders of eye and adnexa
0.732 0.268 0.000
S70-S79 Injuries to the hip and thigh
0.729 0.271 0.000
M51 Other intervertebral disk disorders
0.729 0.271 0.000
M91-M94 Chondropathies
0.728 0.272 0.000
H10-H13 Disorders of conjunctiva
0.727 0.273 0.000
O02 Other abnormal products of conception
0.726 0.274 0.000
N62 Hypertrophy of breast
0.726 0.274 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.725 0.275 0.000
M54.39 Sciatica (Site unspecified)
0.724 0.276 0.000
S61 Open wound of wrist and hand
0.724 0.276 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.721 0.279 0.000
Z45 Adjustment and management of implanted device
0.720 0.280 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.719 0.281 0.000
O36 Maternal care for other known or suspected foetal problems
0.719 0.281 0.000
T79-T79 Certain early complications of trauma
0.718 0.282 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.718 0.282 0.000
S69 Other and unspecified injuries of wrist and hand
0.718 0.282 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.717 0.283 0.000
T81 Complications of procedures, not elsewhere classified
0.714 0.286 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.714 0.286 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.713 0.287 0.000
M54.9 Dorsalgia, unspecified
0.711 0.289 0.000
H25-H28 Disorders of lens
0.711 0.289 0.000
E40-E46 Malnutrition
0.711 0.289 0.000
E65-E68 Obesity and other hyperalimentation
0.710 0.290 0.000
Q60-Q64 Congenital malformations of the urinary system
0.708 0.292 0.000
S64 Injury of nerves at wrist and hand level
0.707 0.293 0.000
M53 Other dorsopathies, not elsewhere classified
0.705 0.294 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.705 0.295 0.000
M60-M63 Disorders of muscles
0.705 0.295 0.000
S80-S89 Injuries to the knee and lower leg
0.705 0.295 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.705 0.295 0.000
Z51 Other medical care
0.703 0.297 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.702 0.298 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.700 0.299 0.000
E70-E90 Metabolic disorders
0.701 0.299 0.000
M47.1 Other spondylosis with myelopathy
0.700 0.300 0.000
E50-E64 Other nutritional deficiencies
0.700 0.300 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.699 0.301 0.000
Z49 Care involving dialysis
0.698 0.302 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.697 0.303 0.000
M40-M43 Deforming dorsopathies
0.696 0.304 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.694 0.306 0.000
O85-O92 Complications predominantly related to the puerperium
0.693 0.307 0.000
E07 Other disorders of thyroid
0.691 0.309 0.000
O20 Haemorrhage in early pregnancy
0.691 0.309 0.000
N64 Other disorders of breast
0.690 0.310 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.690 0.310 0.000
O82 Single delivery by Caesarean section
0.690 0.310 0.000
M46 Other inflammatory spondylopathies
0.689 0.311 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.687 0.313 0.000
S20-S29 Injuries to the thorax
0.687 0.313 0.000
T33-T35 Frostbite
0.687 0.313 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.687 0.313 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.687 0.313 0.000
T00-T07 Injuries involving multiple body regions
0.687 0.313 0.000
S10-S19 Injuries to the neck
0.687 0.313 0.000
Q21 Congenital malformations of cardiac septa
0.686 0.314 0.000
M54.8 Other dorsalgia
0.684 0.316 0.000
M54.4 Lumbago with sciatica
0.684 0.316 0.000
M54.0 Panniculitis affecting regions of neck and back
0.684 0.316 0.000
H35 Other retinal disorders
0.683 0.317 0.000
T87 Complications peculiar to reattachment and amputation
0.679 0.321 0.000
Chapter XX External causes of morbidity and mortality
0.679 0.321 0.000
O16 Unspecified maternal hypertension
0.677 0.323 0.000
Q50-Q56 Congenital malformations of genital organs
0.677 0.323 0.000
M79.6 Pain in limb
0.676 0.324 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.674 0.326 0.000
E03.9 Hypothyroidism, unspecified
0.672 0.328 0.000
S90-S99 Injuries to the ankle and foot
0.672 0.328 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.670 0.330 0.000
O02.1 Missed abortion
0.669 0.330 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.668 0.332 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.668 0.332 0.000
Z52 Donors of organs and tissues
0.667 0.333 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.664 0.336 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.664 0.336 0.000
M15-M19 Arthrosis
0.663 0.337 0.000
E26 Hyperaldosteronism
0.661 0.339 0.000
M49 Spondylopathies in diseases classified elsewhere
0.659 0.341 0.000
M50.3 Other cervical disk degeneration
0.659 0.341 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.657 0.343 0.000
M31 Other necrotising vasculopathies
0.657 0.343 0.000
O36.8 Maternal care for other specified foetal problems
0.656 0.344 0.000
S67 Crushing injury of wrist and hand
0.655 0.345 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.653 0.347 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.653 0.347 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.653 0.347 0.000
S68 Traumatic amputation of wrist and hand
0.651 0.349 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.649 0.351 0.000
O44 Placenta praevia
0.649 0.351 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.649 0.351 0.000
S61.0 Open wound of finger(s) without damage to nail
0.649 0.351 0.000
M47.89 Other spondylosis (Site unspecified)
0.647 0.353 0.000
H40 Glaucoma
0.647 0.353 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.646 0.354 0.000
S40-S49 Injuries to the shoulder and upper arm
0.645 0.355 0.000
M54.16 Radiculopathy (Lumbar region)
0.645 0.355 0.000
T86.1 Kidney transplant failure and rejection
0.645 0.355 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.644 0.356 0.000
H25 Senile cataract
0.644 0.356 0.000
Z51.2 Other chemotherapy
0.643 0.357 0.000
M25 Other joint disorders, not elsewhere classified
0.642 0.358 0.000
U88 Agent resistant to multiple antibiotics
0.642 0.358 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.641 0.358 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.641 0.359 0.000
N20-N23 Urolithiasis
0.641 0.359 0.000
E23 Hypofunction and other disorders of pituitary gland
0.641 0.359 0.000
E05.9 Thyrotoxicosis, unspecified
0.640 0.360 0.000
T86.0 Bone-marrow transplant rejection
0.639 0.361 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.639 0.361 0.000
M50.9 Cervical disk disorder, unspecified
0.639 0.361 0.000
M50.8 Other cervical disk disorders
0.639 0.361 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.639 0.361 0.000
N63 Unspecified lump in breast
0.639 0.361 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.638 0.362 0.000
S65 Injury of blood vessels at wrist and hand level
0.638 0.362 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.638 0.362 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.637 0.363 0.000
M54.22 Cervicalgia (Cervical region)
0.637 0.363 0.000
M21 Other acquired deformities of limbs
0.637 0.363 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.636 0.364 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.636 0.364 0.000
Q80-Q89 Other congenital malformations
0.636 0.364 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.636 0.364 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.636 0.364 0.000
Q35-Q37 Cleft lip and cleft palate
0.636 0.364 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.636 0.364 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.636 0.364 0.000
Q00-Q07 Congenital malformations of the nervous system
0.636 0.364 0.000
E06 Thyroiditis
0.635 0.365 0.000
M50.0 Cervical disk disorder with myelopathy
0.633 0.367 0.000
F60-F69 Disorders of adult personality and behaviour
0.633 0.367 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.632 0.368 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.631 0.369 0.000
S50-S59 Injuries to the elbow and forearm
0.630 0.369 0.000
M45 Ankylosing spondylitis
0.630 0.370 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.630 0.370 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.629 0.371 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.627 0.373 0.000
M54.37 Sciatica (Lumbosacral region)
0.627 0.373 0.000
M54.35 Sciatica (Thoracolumbar region)
0.627 0.373 0.000
M54.34 Sciatica-Thoracic
0.627 0.373 0.000
M54.33 Sciatica-Cervicothoracic
0.627 0.373 0.000
M54.32 Sciatica-Cervical
0.627 0.373 0.000
M54.31 Sciatica-Occipit-atl-axl
0.627 0.373 0.000
M54.30 Sciatica (Multiple sites in spine)
0.627 0.373 0.000
M79.8 Other specified soft tissue disorders
0.627 0.373 0.000
M48 Other spondylopathies
0.626 0.374 0.000
E27 Other disorders of adrenal gland
0.626 0.374 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.626 0.374 0.000
Q21.1 Atrial septal defect
0.626 0.374 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.625 0.375 0.000
E00 Congenital iodine-deficiency syndrome
0.625 0.375 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.625 0.375 0.000
H25.8 Other senile cataract
0.625 0.375 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.623 0.377 0.000
G56.8 Other mononeuropathies of upper limb
0.623 0.377 0.000
Chapter VIII Diseases of the ear and mastoid process
0.621 0.378 0.000
M05-M14 Inflammatory polyarthropathies
0.621 0.379 0.000
Z48.0 Attention to surgical dressings and sutures
0.620 0.380 0.000
H43-H45 Disorders of vitreous body and globe
0.620 0.380 0.000
N99-N99 Other disorders of the genitourinary system
0.620 0.380 0.000
O23 Infections of genito-urinary tract in pregnancy
0.619 0.380 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.619 0.381 0.000
Z54 Convalescence
0.619 0.381 0.000
Z44 Fitting and adjustment of external prosthetic device
0.619 0.381 0.000
M24 Other specific joint derangements
0.618 0.382 0.000
E28 Ovarian dysfunction
0.618 0.382 0.000
G90-G99 Other disorders of the nervous system
0.618 0.382 0.000
T66-T78 Other and unspecified effects of external causes
0.617 0.383 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.614 0.386 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.614 0.386 0.000
Z41 Procedures for purposes other than remedying health state
0.614 0.386 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.612 0.388 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.611 0.389 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.610 0.390 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.608 0.392 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.608 0.392 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.608 0.392 0.000
M47.84 Other spondylosis (Thoracic region)
0.608 0.392 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.608 0.392 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.608 0.392 0.000
M47.9 Spondylosis, unspecified
0.606 0.394 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.605 0.395 0.000
M54.57 Low back pain (Lumbosacral region)
0.604 0.396 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.603 0.397 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.603 0.397 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.603 0.397 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.603 0.397 0.000
T83.2 Mechanical complication of graft of urinary organ
0.603 0.397 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.603 0.397 0.000
E22 Hyperfunction of pituitary gland
0.603 0.397 0.000
N60 Benign mammary dysplasia
0.602 0.398 0.000
N64.5 Other signs and symptoms in breast
0.602 0.398 0.000
H53-H54 Visual disturbances and blindness
0.600 0.399 0.000
M23 Internal derangement of knee
0.600 0.400 0.000
M34 Systemic sclerosis
0.600 0.400 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.600 0.400 0.000
S80 Superficial injury of lower leg
0.599 0.401 0.000
Z33 Pregnant state, incidental
0.599 0.401 0.000
M88 Paget's disease of bone [osteitis deformans]
0.598 0.401 0.000
H52 Disorders of refraction and accommodation
0.598 0.402 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.598 0.402 0.000
E34 Other endocrine disorders
0.598 0.402 0.000
E32 Diseases of thymus
0.598 0.402 0.000
E31 Polyglandular dysfunction
0.598 0.402 0.000
E30 Disorders of puberty, not elsewhere classified
0.598 0.402 0.000
E29 Testicular dysfunction
0.598 0.402 0.000
E25 Adrenogenital disorders
0.598 0.402 0.000
E24 Cushing's syndrome
0.598 0.402 0.000
E20 Hypoparathyroidism
0.598 0.402 0.000
Z48.9 Surgical follow-up care, unspecified
0.596 0.404 0.000
O82.0 Delivery by elective Caesarean section
0.596 0.404 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.596 0.404 0.000
S69.9 Unspecified injury of wrist and hand
0.595 0.405 0.000
M77 Other enthesopathies
0.595 0.405 0.000
E83 Disorders of mineral metabolism
0.595 0.405 0.000
O20.0 Threatened abortion
0.594 0.406 0.000
M51.8 Other specified intervertebral disk disorders
0.593 0.406 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.593 0.406 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.593 0.407 0.000
G54 Nerve root and plexus disorders
0.593 0.407 0.000
Z45.8 Adjustment and management of other implanted devices
0.592 0.408 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.592 0.408 0.000
N72 Inflammatory disease of cervix uteri
0.590 0.410 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.589 0.411 0.000
H11 Other disorders of conjunctiva
0.588 0.411 0.000
M54.59 Low back pain (Site unspecified)
0.588 0.412 0.000
Z72 Problems related to lifestyle
0.587 0.413 0.000
O15 Eclampsia
0.587 0.413 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.587 0.413 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.587 0.413 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.587 0.413 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.587 0.413 0.000
Z47 Other orthopaedic follow-up care
0.587 0.413 0.000
M47.2 Other spondylosis with radiculopathy
0.585 0.414 0.000
M00 Pyogenic arthritis
0.585 0.415 0.000
O03 Spontaneous abortion
0.585 0.415 0.000
H33 Retinal detachments and breaks
0.584 0.416 0.000
S79 Other and unspecified injuries of hip and thigh
0.584 0.416 0.000
Z48.8 Other specified surgical follow-up care
0.583 0.417 0.000
H57 Other disorders of eye and adnexa
0.583 0.417 0.000
H49 Paralytic strabismus
0.583 0.417 0.000
M76 Enthesopathies of lower limb, excluding foot
0.581 0.419 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.581 0.419 0.000
M71 Other bursopathies
0.581 0.419 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.581 0.419 0.000
Q61 Cystic kidney disease
0.580 0.419 0.000
M65-M68 Disorders of synovium and tendon
0.580 0.420 0.000
F99-F99 Unspecified mental disorder
0.580 0.420 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.579 0.421 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.579 0.421 0.000
O29 Complications of anaesthesia during pregnancy
0.578 0.421 0.000
O28 Abnormal findings on antenatal screening of mother
0.578 0.421 0.000
O24 Diabetes mellitus in pregnancy
0.578 0.421 0.000
O22 Venous complications in pregnancy
0.578 0.421 0.000
O21 Excessive vomiting in pregnancy
0.578 0.421 0.000
O25 Malnutrition in pregnancy
0.578 0.421 0.000
H40.0 Glaucoma suspect
0.578 0.422 0.000
O45 Premature separation of placenta [abruptio placentae]
0.578 0.422 0.000
O43 Placental disorders
0.578 0.422 0.000
O41 Other disorders of amniotic fluid and membranes
0.578 0.422 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.578 0.422 0.000
O33 Maternal care for known or suspected disproportion
0.578 0.422 0.000
O31 Complications specific to multiple gestation
0.578 0.422 0.000
O30 Multiple gestation
0.578 0.422 0.000
O40 Polyhydramnios
0.578 0.422 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.577 0.422 0.000
O07 Failed attempted abortion
0.577 0.422 0.000
O06 Unspecified abortion
0.577 0.422 0.000
O05 Other abortion
0.577 0.422 0.000
O01 Hydatidiform mole
0.577 0.422 0.000
O00 Ectopic pregnancy
0.577 0.422 0.000
S64.4 Injury of digital nerve of other finger
0.576 0.424 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.574 0.426 0.000
Z43 Attention to artificial openings
0.574 0.426 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.573 0.427 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.573 0.427 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.572 0.427 0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue
0.572 0.428 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.572 0.428 0.000
T86.4 Liver transplant failure and rejection
0.572 0.428 0.000
T86.3 Heart-lung transplant failure and rejection
0.572 0.428 0.000
T86.2 Heart transplant failure and rejection
0.572 0.428 0.000
M18 Arthrosis of first carpometacarpal joint
0.572 0.428 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.571 0.429 0.000
S81 Open wound of lower leg
0.571 0.429 0.000
M89 Other disorders of bone
0.570 0.430 0.000
O84 Multiple delivery
0.569 0.430 0.000
O83 Other assisted single delivery
0.569 0.430 0.000
O81 Single delivery by forceps and vacuum extractor
0.569 0.430 0.000
N23 Unspecified renal colic
0.569 0.431 0.000
O66 Other obstructed labour
0.568 0.431 0.000
M79.1 Myalgia
0.568 0.432 0.000
N75 Diseases of Bartholin's gland
0.568 0.432 0.000
Z51.3 Blood transfusion without reported diagnosis
0.567 0.433 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.566 0.434 0.000
F80-F89 Disorders of psychological development
0.566 0.434 0.000
F70-F79 Mental retardation
0.566 0.434 0.000
M85 Other disorders of bone density and structure
0.566 0.434 0.000
G70-G73 Diseases of myoneural junction and muscle
0.565 0.434 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.565 0.434 0.000
N61 Inflammatory disorders of breast
0.564 0.436 0.000
M86 Osteomyelitis
0.562 0.438 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.562 0.438 0.000
M33 Dermatopolymyositis
0.562 0.438 0.000
M32 Systemic lupus erythematosus
0.562 0.438 0.000
M30 Polyarteritis nodosa and related conditions
0.562 0.438 0.000
X60-X84 Intentional self-harm
0.562 0.438 0.000
E07.9 Disorder of thyroid, unspecified
0.561 0.438 0.000
N64.8 Other specified disorders of breast
0.560 0.440 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.560 0.440 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.558 0.442 0.000
H31 Other disorders of choroid
0.558 0.442 0.000
H30 Chorioretinal inflammation
0.558 0.442 0.000
F30-F39 Mood [affective] disorders
0.558 0.442 0.000
H35.3 Degeneration of macula and posterior pole
0.558 0.442 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.557 0.443 0.000
H36 Retinal disorders in diseases classified elsewhere
0.557 0.443 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.556 0.444 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.556 0.444 0.000
M54.19 Radiculopathy (Site unspecified)
0.555 0.445 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.555 0.445 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.555 0.445 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.555 0.445 0.000
M54.14 Radiculopathy (Thoracic region)
0.555 0.445 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.555 0.445 0.000
M54.12 Radiculopathy (Cervical region)
0.555 0.445 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.555 0.445 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.555 0.445 0.000
O63 Long labour
0.555 0.445 0.000
H35.9 Retinal disorder, unspecified
0.555 0.445 0.000
Z49.0 Preparatory care for dialysis
0.554 0.446 0.000
Z46 Fitting and adjustment of other devices
0.553 0.447 0.000
M54.55 Low back pain (Thoracolumbar region)
0.553 0.447 0.000
M54.54 Low back pain-Thoracic
0.553 0.447 0.000
M54.53 Low back pain-Cervicothoracic
0.553 0.447 0.000
M54.52 Low back pain-Cervical
0.553 0.447 0.000
M54.51 Low back pain-Occipit-atl-axl
0.553 0.447 0.000
M54.50 Low back pain (Multiple sites in spine)
0.553 0.447 0.000
M90 Osteopathies in diseases classified elsewhere
0.553 0.447 0.000
M87 Osteonecrosis
0.553 0.447 0.000
Q28 Other congenital malformations of circulatory system
0.552 0.448 0.000
Q27 Other congenital malformations of peripheral vascular system
0.552 0.448 0.000
Q26 Congenital malformations of great veins
0.552 0.448 0.000
Q25 Congenital malformations of great arteries
0.552 0.448 0.000
Q24 Other congenital malformations of heart
0.552 0.448 0.000
Q23 Congenital malformations of aortic and mitral valves
0.552 0.448 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.552 0.448 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.552 0.448 0.000
E05.8 Other thyrotoxicosis
0.552 0.448 0.000
E05.5 Thyroid crisis or storm
0.552 0.448 0.000
E05.4 Thyrotoxicosis factitia
0.552 0.448 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.552 0.448 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.552 0.448 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.552 0.448 0.000
M54.69 Pain in thoracic spine-Site unspe
0.552 0.448 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.552 0.448 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.552 0.448 0.000
M54.66 Pain in thoracic spine-Lumbar
0.552 0.448 0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.552 0.448 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.552 0.448 0.000
M54.62 Pain in thoracic spine-Cervical
0.552 0.448 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.552 0.448 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.552 0.448 0.000
M54.29 Cervicalgia-Site unspe
0.552 0.448 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.552 0.448 0.000
M54.27 Cervicalgia-Lumbosacral
0.552 0.448 0.000
M54.26 Cervicalgia-Lumbar
0.552 0.448 0.000
M54.25 Cervicalgia-Thoracolumbar
0.552 0.448 0.000
M54.24 Cervicalgia-Thoracic
0.552 0.448 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.552 0.448 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.552 0.448 0.000
M54.20 Cervicalgia-Mult site
0.552 0.448 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.551 0.449 0.000
T88.9 Complication of surgical and medical care, unspecified
0.550 0.449 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.550 0.449 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.550 0.449 0.000
T88.5 Other complications of anaesthesia
0.550 0.449 0.000
T88.4 Failed or difficult intubation
0.550 0.449 0.000
T88.3 Malignant hyperthermia due to anaesthesis
0.550 0.449 0.000
T88.2 Shock due to anaesthesia
0.550 0.449 0.000
T88.1 Other complications following immunisation, not elsewhere classified
0.550 0.449 0.000
T88.0 Infection following immunisation
0.550 0.449 0.000
O47 False labour
0.550 0.450 0.000
E86 Volume depletion
0.550 0.450 0.000
F25 Schizoaffective disorders
0.550 0.450 0.000
M79.63 Pain in limb (Forearm)
0.549 0.451 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.548 0.451 0.000
O62 Abnormalities of forces of labour
0.548 0.452 0.000
O36.6 Maternal care for excessive foetal growth
0.548 0.452 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.546 0.454 0.000
T14 Injury of unspecified body region
0.546 0.454 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.546 0.454 0.000
H42 Glaucoma in diseases classified elsewhere
0.546 0.454 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.546 0.454 0.000
O97 Death from sequelae of direct obstetric causes
0.546 0.454 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.546 0.454 0.000
O95 Obstetric death of unspecified cause
0.546 0.454 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.546 0.454 0.000
M94 Other disorders of cartilage
0.545 0.454 0.000
H46 Optic neuritis
0.545 0.455 0.000
M54.56 Low back pain (Lumbar region)
0.545 0.455 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.545 0.455 0.000
M80 Osteoporosis with pathological fracture
0.544 0.456 0.000
E53 Deficiency of other B group vitamins
0.544 0.456 0.000
G56.2 Lesion of ulnar nerve
0.544 0.456 0.000
E46 Unspecified protein-energy malnutrition
0.543 0.457 0.000
E66 Obesity
0.543 0.457 0.000
H40.1 Primary open-angle glaucoma
0.542 0.458 0.000
Z72.1 Alcohol use
0.542 0.458 0.000
E03.8 Other specified hypothyroidism
0.542 0.458 0.000
E03.5 Myxoedema coma
0.542 0.458 0.000
E03.4 Atrophy of thyroid (acquired)
0.542 0.458 0.000
E03.3 Postinfectious hypothyroidism
0.542 0.458 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.542 0.458 0.000
E03.1 Congenital hypothyroidism without goitre
0.542 0.458 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.542 0.458 0.000
M31.3 Wegener's granulomatosis
0.541 0.459 0.000
G58 Other mononeuropathies
0.540 0.460 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.540 0.460 0.000
G52 Disorders of other cranial nerves
0.540 0.460 0.000
E10-E14 Diabetes mellitus
0.540 0.460 0.000
Z40.9 Prophylactic surgery, unspecified
0.540 0.460 0.000
Z40.8 Other prophylactic surgery
0.540 0.460 0.000
M72 Fibroblastic disorders
0.539 0.461 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.539 0.461 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.539 0.461 0.000
M02 Reactive arthropathies
0.539 0.461 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.539 0.461 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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