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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs150006865
log Bayes Factor = 16.2642
Chromosome 2   position 195,586,736  (GRCh37) Explore rs150006865 on Ensembl!
Variant rs150006865 is part of Cluster X0039

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
I50 Heart failure
0.992 0.008 0.000
M50-M54 Other dorsopathies
0.990 0.010 0.000
I51 Complications and ill-defined descriptions of heart disease
0.989 0.011 0.000
M25 Other joint disorders, not elsewhere classified
0.987 0.013 0.000
Chapter XIV Diseases of the genitourinary system
0.985 0.015 0.000
C79 Secondary malignant neoplasm of other sites
0.984 0.016 0.000
N17-N19 Renal failure
0.983 0.017 0.000
E70-E90 Metabolic disorders
0.982 0.018 0.000
N18 Chronic renal failure
0.981 0.019 0.000
I20-I25 Ischaemic heart diseases
0.977 0.023 0.000
I44 Atrioventricular and left bundle-branch block
0.976 0.024 0.000
D10-D36 Benign neoplasms
0.974 0.026 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.973 0.027 0.000
M54 Dorsalgia
0.970 0.030 0.000
I50.9 Heart failure, unspecified
0.970 0.030 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.970 0.030 0.000
I25 Chronic ischaemic heart disease
0.967 0.033 0.000
N18.3 Chronic kidney disease, stage 3
0.965 0.035 0.000
E87.6 Hypokalaemia
0.965 0.035 0.000
M80-M85 Disorders of bone density and structure
0.963 0.037 0.000
I60-I69 Cerebrovascular diseases
0.959 0.041 0.000
E10-E14 Diabetes mellitus
0.958 0.042 0.000
N10-N16 Renal tubulo-interstitial diseases
0.958 0.042 0.000
M25.5 Pain in joint
0.955 0.045 0.000
M22 Disorders of patella
0.951 0.049 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.950 0.050 0.000
I50.1 Left ventricular failure
0.948 0.052 0.000
S00-S09 Injuries to the head
0.947 0.053 0.000
I44.7 Left bundle-branch block, unspecified
0.944 0.056 0.000
I34 Nonrheumatic mitral valve disorders
0.942 0.058 0.000
S40-S49 Injuries to the shoulder and upper arm
0.941 0.059 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.937 0.063 0.000
M25.51 Pain in joint (Shoulder region)
0.935 0.065 0.000
Chapter I Certain infectious and parasitic diseases
0.931 0.069 0.000
M51 Other intervertebral disk disorders
0.929 0.071 0.000
E11 Non-insulin-dependent diabetes mellitus
0.925 0.075 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.924 0.076 0.000
D12.3 Transverse colon
0.924 0.076 0.000
N13 Obstructive and reflux uropathy
0.923 0.077 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.920 0.080 0.000
I51.9 Heart disease, unspecified
0.920 0.080 0.000
Chapter XXI Factors influencing health status and contact with health services
0.919 0.081 0.000
Z45 Adjustment and management of implanted device
0.917 0.083 0.000
D27 Benign neoplasm of ovary
0.916 0.084 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.914 0.086 0.000
C34 Malignant neoplasm of bronchus and lung
0.909 0.091 0.000
I34.0 Mitral (valve) insufficiency
0.908 0.092 0.000
N18.4 Chronic kidney disease, stage 4
0.905 0.095 0.000
M40-M43 Deforming dorsopathies
0.905 0.095 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.901 0.099 0.000
M54.1 Radiculopathy
0.900 0.100 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.897 0.103 0.000
Z51 Other medical care
0.897 0.103 0.000
Z45.2 Adjustment and management of vascular access device
0.897 0.103 0.000
C77.3 Axillary and upper limb lymph nodes
0.895 0.105 0.000
I51.7 Cardiomegaly
0.894 0.106 0.000
M25.57 Pain in joint (Ankle and foot)
0.891 0.109 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.891 0.109 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.889 0.111 0.000
I44.2 Atrioventricular block, complete
0.886 0.114 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.883 0.117 0.000
E11.3 With ophthalmic complications
0.881 0.119 0.000
C50-C50 Malignant neoplasm of breast
0.879 0.121 0.000
Z51.3 Blood transfusion without reported diagnosis
0.877 0.123 0.000
T66-T78 Other and unspecified effects of external causes
0.877 0.123 0.000
N19 Unspecified renal failure
0.877 0.123 0.000
I25.5 Ischaemic cardiomyopathy
0.870 0.130 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.869 0.131 0.000
M80 Osteoporosis with pathological fracture
0.868 0.132 0.000
I46 Cardiac arrest
0.867 0.133 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.866 0.134 0.000
Z45.8 Adjustment and management of other implanted devices
0.865 0.135 0.000
M31 Other necrotising vasculopathies
0.864 0.136 0.000
Chapter XXII Codes for special purposes
0.863 0.137 0.000
A30-A49 Other bacterial diseases
0.861 0.139 0.000
T79-T79 Certain early complications of trauma
0.857 0.143 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.853 0.147 0.000
M51.2 Other specified intervertebral disk displacement
0.852 0.148 0.000
Z49 Care involving dialysis
0.847 0.153 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.846 0.154 0.000
N00-N08 Glomerular diseases
0.846 0.154 0.000
M25.4 Effusion of joint
0.845 0.155 0.000
M24 Other specific joint derangements
0.842 0.158 0.000
Chapter XX External causes of morbidity and mortality
0.841 0.159 0.000
Chapter VII Diseases of the eye and adnexa
0.839 0.161 0.000
E87.0 Hyperosmolality and hypernatraemia
0.839 0.161 0.000
I65.2 Occlusion and stenosis of carotid artery
0.838 0.162 0.000
C51-C58 Malignant neoplasms of female genital organs
0.838 0.162 0.000
D22 Melanocytic naevi
0.838 0.162 0.000
I80 Phlebitis and thrombophlebitis
0.837 0.163 0.000
M65-M68 Disorders of synovium and tendon
0.836 0.164 0.000
C34.9 Bronchus or lung, unspecified
0.836 0.164 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.836 0.164 0.000
M43 Other deforming dorsopathies
0.834 0.166 0.000
C79.6 Secondary malignant neoplasm of ovary
0.832 0.168 0.000
A41 Other septicaemia
0.831 0.169 0.000
I67 Other cerebrovascular diseases
0.831 0.169 0.000
I25.2 Old myocardial infarction
0.830 0.170 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.830 0.170 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.830 0.170 0.000
D11 Benign neoplasm of major salivary glands
0.829 0.171 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.828 0.172 0.000
I51.6 Cardiovascular disease, unspecified
0.827 0.173 0.000
N18.5 Chronic kidney disease, stage 5
0.827 0.173 0.000
M22.4 Chondromalacia patellae
0.826 0.174 0.000
M22.2 Patellofemoral disorders
0.826 0.174 0.000
M05-M14 Inflammatory polyarthropathies
0.824 0.176 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.824 0.176 0.000
N13.3 Other and unspecified hydronephrosis
0.822 0.178 0.000
N20-N23 Urolithiasis
0.821 0.179 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.819 0.181 0.000
Z41 Procedures for purposes other than remedying health state
0.818 0.182 0.000
I51.8 Other ill-defined heart diseases
0.817 0.183 0.000
E20-E35 Disorders of other endocrine glands
0.817 0.183 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.817 0.183 0.000
S01 Open wound of head
0.816 0.184 0.000
M84 Disorders of continuity of bone
0.816 0.184 0.000
D00-D09 In situ neoplasms
0.816 0.184 0.000
D24 Benign neoplasm of breast
0.814 0.186 0.000
S02 Fracture of skull and facial bones
0.812 0.188 0.000
M25.8 Other specified joint disorders
0.812 0.188 0.000
S42 Fracture of shoulder and upper arm
0.811 0.188 0.000
M54.5 Low back pain
0.808 0.192 0.000
D12.4 Descending colon
0.806 0.194 0.000
S06 Intracranial injury
0.804 0.196 0.000
I44.0 Atrioventricular block, first degree
0.799 0.201 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.798 0.202 0.000
W00-W19 Falls
0.798 0.202 0.000
M85 Other disorders of bone density and structure
0.797 0.203 0.000
I30 Acute pericarditis
0.797 0.203 0.000
S60-S69 Injuries to the wrist and hand
0.796 0.204 0.000
E11.4 With neurological complications
0.796 0.204 0.000
E87.5 Hyperkalaemia
0.793 0.207 0.000
C50 Malignant neoplasm of breast
0.793 0.207 0.000
T78 Adverse effects, not elsewhere classified
0.792 0.208 0.000
M21 Other acquired deformities of limbs
0.791 0.209 0.000
M54.2 Cervicalgia
0.790 0.210 0.000
N18.0 End-stage renal disease
0.790 0.210 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.787 0.213 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.785 0.215 0.000
I20 Angina pectoris
0.785 0.215 0.000
M54.6 Pain in thoracic spine
0.784 0.216 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.784 0.216 0.000
Z50 Care involving use of rehabilitation procedures
0.782 0.218 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.781 0.219 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.781 0.219 0.000
I22 Subsequent myocardial infarction
0.780 0.220 0.000
I67.8 Other specified cerebrovascular diseases
0.779 0.221 0.000
D80-D89 Certain disorders involving the immune mechanism
0.778 0.222 0.000
Z45.1 Adjustment and management of infusion pump
0.778 0.222 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.777 0.223 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.776 0.224 0.000
D68 Other coagulation defects
0.775 0.225 0.000
M54.4 Lumbago with sciatica
0.775 0.225 0.000
M25.3 Other instability of joint
0.775 0.225 0.000
M54.9 Dorsalgia, unspecified
0.773 0.227 0.000
I63 Cerebral infarction
0.773 0.227 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.773 0.227 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.772 0.228 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.771 0.229 0.000
I60 Subarachnoid haemorrhage
0.771 0.229 0.000
E11.5 With peripheral circulatory complications
0.770 0.230 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.767 0.233 0.000
E78.2 Mixed hyperlipidaemia
0.766 0.234 0.000
Z49.1 Extracorporeal dialysis
0.764 0.236 0.000
E50-E64 Other nutritional deficiencies
0.763 0.237 0.000
S90-S99 Injuries to the ankle and foot
0.760 0.240 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.760 0.240 0.000
S41 Open wound of shoulder and upper arm
0.759 0.241 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.759 0.241 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.758 0.242 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.757 0.242 0.000
D12.1 Appendix
0.757 0.243 0.000
E10 Insulin-dependent diabetes mellitus
0.756 0.244 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.756 0.244 0.000
M91-M94 Chondropathies
0.755 0.245 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.755 0.245 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.755 0.245 0.000
M43.1 Spondylolisthesis
0.755 0.245 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.755 0.245 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.754 0.246 0.000
H30-H36 Disorders of choroid and retina
0.753 0.247 0.000
N10 Acute tubulo-interstitial nephritis
0.753 0.247 0.000
I72 Other aneurysm
0.753 0.247 0.000
S42.0 Fracture of clavicle
0.752 0.248 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.751 0.249 0.000
M22.8 Other disorders of patella
0.751 0.249 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.750 0.249 0.000
D45 Polycythaemia vera
0.750 0.250 0.000
D12.7 Rectosigmoid junction
0.749 0.251 0.000
I45 Other conduction disorders
0.748 0.252 0.000
D16 Benign neoplasm of bone and articular cartilage
0.748 0.252 0.000
C34.0 Main bronchus
0.747 0.253 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.747 0.253 0.000
M05 Seropositive rheumatoid arthritis
0.746 0.254 0.000
M31.3 Wegener's granulomatosis
0.746 0.254 0.000
T78.4 Allergy, unspecified
0.745 0.255 0.000
C79.2 Secondary malignant neoplasm of skin
0.745 0.255 0.000
S80-S89 Injuries to the knee and lower leg
0.744 0.256 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.744 0.256 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.744 0.256 0.000
A00-A09 Intestinal infectious diseases
0.744 0.256 0.000
M34 Systemic sclerosis
0.744 0.256 0.000
N21 Calculus of lower urinary tract
0.743 0.257 0.000
M35 Other systemic involvement of connective tissue
0.742 0.258 0.000
S50-S59 Injuries to the elbow and forearm
0.742 0.258 0.000
I33 Acute and subacute endocarditis
0.741 0.259 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.740 0.260 0.000
M22.3 Other derangements of patella
0.740 0.260 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.740 0.260 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.740 0.260 0.000
Z51.1 Chemotherapy session for neoplasm
0.739 0.261 0.000
D04 Carcinoma in situ of skin
0.737 0.263 0.000
M81 Osteoporosis without pathological fracture
0.737 0.263 0.000
E40-E46 Malnutrition
0.735 0.265 0.000
C77.2 Intra-abdominal lymph nodes
0.735 0.265 0.000
E73 Lactose intolerance
0.734 0.266 0.000
M67 Other disorders of synovium and tendon
0.733 0.267 0.000
M00-M03 Infectious arthropathies
0.732 0.268 0.000
C78.0 Secondary malignant neoplasm of lung
0.732 0.268 0.000
S10-S19 Injuries to the neck
0.731 0.269 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.730 0.270 0.000
M25.50 Pain in joint (Multiple sites)
0.729 0.271 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.729 0.271 0.000
D34 Benign neoplasm of thyroid gland
0.729 0.271 0.000
M60-M63 Disorders of muscles
0.728 0.272 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.728 0.272 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.727 0.273 0.000
D12.9 Anus and anal canal
0.727 0.273 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.725 0.275 0.000
H36 Retinal disorders in diseases classified elsewhere
0.724 0.276 0.000
N18.9 Chronic renal failure, unspecified
0.724 0.276 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.724 0.276 0.000
N13.4 Hydroureter
0.722 0.278 0.000
M25.47 Effusion of joint (Ankle and foot)
0.722 0.278 0.000
Z51.5 Palliative care
0.721 0.279 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.721 0.279 0.000
I25.3 Aneurysm of heart
0.720 0.280 0.000
M51.9 Intervertebral disk disorder, unspecified
0.720 0.280 0.000
S70-S79 Injuries to the hip and thigh
0.720 0.280 0.000
I46.9 Cardiac arrest, unspecified
0.718 0.281 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.717 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
C32 Malignant neoplasm of larynx
0.717 0.283 0.000
S05 Injury of eye and orbit
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
E11.1 With ketoacidosis
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.285 0.000
M33 Dermatopolymyositis
0.715 0.285 0.000
M32 Systemic lupus erythematosus
0.715 0.285 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.285 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.285 0.000
S00 Superficial injury of head
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.285 0.000
E27 Other disorders of adrenal gland
0.714 0.286 0.000
M25.40 Effusion of joint (Multiple sites)
0.713 0.287 0.000
C34.1 Upper lobe, bronchus or lung
0.713 0.287 0.000
B95-B98 Bacterial, viral and other infectious agents
0.713 0.287 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.712 0.288 0.000
V40-V49 Car occupant injured in transport accident
0.712 0.288 0.000
M54.12 Radiculopathy (Cervical region)
0.712 0.288 0.000
E83 Disorders of mineral metabolism
0.712 0.288 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.712 0.288 0.000
N13.6 Pyonephrosis
0.711 0.289 0.000
S42.00 Fracture of clavicle (closed)
0.710 0.290 0.000
I46.0 Cardiac arrest with successful resuscitation
0.709 0.291 0.000
I51.5 Myocardial degeneration
0.709 0.291 0.000
I51.4 Myocarditis, unspecified
0.709 0.291 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.709 0.291 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.709 0.291 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.709 0.291 0.000
I51.0 Cardiac septal defect, acquired
0.709 0.291 0.000
E87.3 Alkalosis
0.708 0.292 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.708 0.292 0.000
Chapter V Mental and behavioural disorders
0.708 0.292 0.000
M25.2 Flail joint
0.708 0.292 0.000
M25.1 Fistula of joint
0.708 0.292 0.000
M25.0 Haemarthrosis
0.708 0.292 0.000
W07 Fall involving chair
0.707 0.293 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.706 0.293 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.706 0.294 0.000
B35-B49 Mycoses
0.705 0.295 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.705 0.295 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.705 0.295 0.000
U80 Agent resistant to penicillin and related antibiotics
0.705 0.295 0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.705 0.295 0.000
H36.0 Diabetic retinopathy
0.704 0.296 0.000
E85 Amyloidosis
0.704 0.296 0.000
E84 Cystic fibrosis
0.704 0.296 0.000
E79 Disorders of purine and pyrimidine metabolism
0.704 0.296 0.000
E77 Disorders of glycoprotein metabolism
0.704 0.296 0.000
E76 Disorders of glycosaminoglycan metabolism
0.704 0.296 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.704 0.296 0.000
E74 Other disorders of carbohydrate metabolism
0.704 0.296 0.000
E72 Other disorders of amino-acid metabolism
0.704 0.296 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.704 0.296 0.000
E70 Disorders of aromatic amino-acid metabolism
0.704 0.296 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.704 0.296 0.000
N18.8 Other chronic renal failure
0.703 0.297 0.000
N18.1 Chronic kidney disease, stage 1
0.703 0.297 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.703 0.297 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.703 0.297 0.000
M25.9 Joint disorder, unspecified
0.702 0.298 0.000
D13.1 Stomach
0.701 0.299 0.000
I23 Certain current complications following acute myocardial infarction
0.700 0.299 0.000
I44.6 Other and unspecified fascicular block
0.700 0.300 0.000
I44.5 Left posterior fascicular block
0.700 0.300 0.000
I44.4 Left anterior fascicular block
0.700 0.300 0.000
I44.3 Other and unspecified atrioventricular block
0.700 0.300 0.000
M54.59 Low back pain (Site unspecified)
0.698 0.302 0.000
D75 Other diseases of blood and blood-forming organs
0.698 0.302 0.000
D31 Benign neoplasm of eye and adnexa
0.698 0.302 0.000
D30 Benign neoplasm of urinary organs
0.698 0.302 0.000
D29 Benign neoplasm of male genital organs
0.698 0.302 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.698 0.302 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.698 0.302 0.000
D19 Benign neoplasm of mesothelial tissue
0.698 0.302 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.698 0.302 0.000
I86 Varicose veins of other sites
0.698 0.302 0.000
C80 Malignant neoplasm without specification of site
0.698 0.302 0.000
E87.4 Mixed disorder of acid-base balance
0.697 0.303 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.696 0.303 0.000
M54.19 Radiculopathy (Site unspecified)
0.696 0.304 0.000
B99-B99 Other infectious diseases
0.696 0.304 0.000
Z50.2 Alcohol rehabilitation
0.696 0.304 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.696 0.304 0.000
Z50.1 Other physical therapy
0.696 0.304 0.000
M54.8 Other dorsalgia
0.695 0.305 0.000
M54.0 Panniculitis affecting regions of neck and back
0.695 0.305 0.000
Z49.0 Preparatory care for dialysis
0.695 0.305 0.000
M86-M90 Other osteopathies
0.694 0.305 0.000
Z51.2 Other chemotherapy
0.694 0.306 0.000
Q00-Q07 Congenital malformations of the nervous system
0.694 0.306 0.000
S01.8 Open wound of other parts of head
0.693 0.307 0.000
I25.6 Silent myocardial ischaemia
0.693 0.307 0.000
I25.4 Coronary artery aneurysm
0.693 0.307 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.693 0.307 0.000
M25.52 Pain in joint (Upper arm)
0.692 0.308 0.000
D21.2 Connective and other soft tissue of lower limb, including hip
0.692 0.308 0.000
M83 Adult osteomalacia
0.691 0.309 0.000
M82 Osteoporosis in diseases classified elsewhere
0.691 0.309 0.000
D11.0 Parotid gland
0.691 0.309 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.690 0.310 0.000
D68.2 Hereditary deficiency of other clotting factors
0.690 0.310 0.000
M25.54 Pain in joint (Hand)
0.688 0.312 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.687 0.312 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.687 0.312 0.000
N21.0 Calculus in bladder
0.687 0.313 0.000
C50.8 Overlapping lesion of breast
0.687 0.313 0.000
I99 Other and unspecified disorders of circulatory system
0.687 0.313 0.000
E12 Malnutrition-related diabetes mellitus
0.687 0.313 0.000
E13 Other specified diabetes mellitus
0.687 0.313 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.686 0.313 0.000
N15 Other renal tubulo-interstitial diseases
0.686 0.313 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.686 0.313 0.000
C44 Other malignant neoplasms of skin
0.685 0.315 0.000
M25.58 Pain in joint (Other)
0.684 0.316 0.000
T91 Sequelae of injuries of neck and trunk
0.684 0.316 0.000
M21.0 Valgus deformity, not elsewhere classified
0.684 0.316 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.683 0.317 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.683 0.317 0.000
M43.0 Spondylolysis
0.682 0.318 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.682 0.318 0.000
M22.1 Recurrent subluxation of patella
0.682 0.318 0.000
M22.9 Disorder of patella, unspecified
0.682 0.318 0.000
M22.0 Recurrent dislocation of patella
0.682 0.318 0.000
E11.2 With renal complications
0.681 0.319 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.681 0.319 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.681 0.319 0.000
C31 Malignant neoplasm of accessory sinuses
0.681 0.319 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.681 0.319 0.000
C37 Malignant neoplasm of thymus
0.681 0.319 0.000
C33 Malignant neoplasm of trachea
0.681 0.319 0.000
I77 Other disorders of arteries and arterioles
0.681 0.319 0.000
S81 Open wound of lower leg
0.681 0.319 0.000
C34.3 Lower lobe, bronchus or lung
0.681 0.319 0.000
D32 Benign neoplasm of meninges
0.681 0.319 0.000
Q50-Q56 Congenital malformations of genital organs
0.681 0.319 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.680 0.320 0.000
M53 Other dorsopathies, not elsewhere classified
0.679 0.320 0.000
S20-S29 Injuries to the thorax
0.679 0.321 0.000
S08 Traumatic amputation of part of head
0.679 0.321 0.000
S07 Crushing injury of head
0.679 0.321 0.000
S04 Injury of cranial nerves
0.679 0.321 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.679 0.321 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.679 0.321 0.000
T92 Sequelae of injuries of upper limb
0.678 0.322 0.000
N20 Calculus of kidney and ureter
0.678 0.322 0.000
E10.3 With ophthalmic complications
0.678 0.322 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.676 0.324 0.000
N25-N29 Other disorders of kidney and ureter
0.676 0.324 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.675 0.325 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.675 0.325 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.675 0.325 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.675 0.325 0.000
M25.59 Pain in joint (Site unspecified)
0.675 0.325 0.000
S48 Traumatic amputation of shoulder and upper arm
0.675 0.325 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.675 0.325 0.000
S44 Injury of nerves at shoulder and upper arm level
0.675 0.325 0.000
S47 Crushing injury of shoulder and upper arm
0.675 0.325 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.674 0.326 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.673 0.327 0.000
X20-X29 Contact with venomous animals and plants
0.673 0.327 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.673 0.327 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.672 0.328 0.000
D55-D59 Haemolytic anaemias
0.671 0.329 0.000
M25.7 Osteophyte
0.669 0.331 0.000
A80-A89 Viral infections of the central nervous system
0.668 0.332 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.668 0.332 0.000
D12.5 Sigmoid colon
0.668 0.332 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.667 0.332 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.667 0.332 0.000
B65-B83 Helminthiases
0.667 0.332 0.000
B50-B64 Protozoal diseases
0.667 0.332 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.667 0.332 0.000
A75-A79 Rickettsioses
0.667 0.332 0.000
A70-A74 Other diseases caused by chlamydiae
0.667 0.332 0.000
A65-A69 Other spirochaetal diseases
0.667 0.332 0.000
A20-A28 Certain zoonotic bacterial diseases
0.667 0.332 0.000
A15-A19 Tuberculosis
0.667 0.332 0.000
M31.6 Other giant cell arteritis
0.667 0.333 0.000
S62 Fracture at wrist and hand level
0.667 0.333 0.000
S02.0 Fracture of vault of skull
0.666 0.334 0.000
M51.3 Other specified intervertebral disk degeneration
0.666 0.334 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.666 0.334 0.000
M51.4 Schmorl's nodes
0.666 0.334 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.665 0.334 0.000
C54 Malignant neoplasm of corpus uteri
0.665 0.335 0.000
Z52 Donors of organs and tissues
0.665 0.335 0.000
E87.2 Acidosis
0.664 0.336 0.000
E11.6 With other specified complications
0.664 0.336 0.000
E11.8 With unspecified complications
0.663 0.336 0.000
E11.7 With multiple complications
0.663 0.336 0.000
E11.0 With coma
0.663 0.336 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.663 0.336 0.000
C34.2 Middle lobe, bronchus or lung
0.663 0.337 0.000
N11 Chronic tubulo-interstitial nephritis
0.663 0.337 0.000
I62 Other nontraumatic intracranial haemorrhage
0.662 0.338 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.662 0.338 0.000
T90 Sequelae of injuries of head
0.662 0.338 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.662 0.338 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.662 0.338 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.662 0.338 0.000
M45-M49 Spondylopathies
0.662 0.338 0.000
N03 Chronic nephritic syndrome
0.661 0.339 0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.661 0.339 0.000
H10-H13 Disorders of conjunctiva
0.660 0.340 0.000
Z54 Convalescence
0.660 0.340 0.000
Z44 Fitting and adjustment of external prosthetic device
0.660 0.340 0.000
N60-N64 Disorders of breast
0.659 0.341 0.000
N18.2 Chronic kidney disease, stage 2
0.659 0.341 0.000
S42.4 Fracture of lower end of humerus
0.659 0.341 0.000
M41 Scoliosis
0.659 0.341 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.657 0.343 0.000
Z45.3 Adjustment and management of implanted hearing device
0.657 0.343 0.000
W19 Unspecified fall
0.657 0.343 0.000
S02.8 Fractures of other skull and facial bones
0.657 0.343 0.000
E14 Unspecified diabetes mellitus
0.656 0.344 0.000
I61 Intracerebral haemorrhage
0.656 0.344 0.000
E78.8 Other disorders of lipoprotein metabolism
0.656 0.344 0.000
T98 Sequelae of other and unspecified effects of external causes
0.655 0.345 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.655 0.345 0.000
Q80-Q89 Other congenital malformations
0.655 0.345 0.000
Q35-Q37 Cleft lip and cleft palate
0.655 0.345 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.655 0.345 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.655 0.345 0.000
N99-N99 Other disorders of the genitourinary system
0.654 0.345 0.000
S00.0 Superficial injury of scalp
0.655 0.345 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.654 0.346 0.000
I22.8 Subsequent myocardial infarction of other sites
0.654 0.346 0.000
D60-D64 Aplastic and other anaemias
0.654 0.346 0.000
D11.9 Major salivary gland, unspecified
0.654 0.346 0.000
H18 Other disorders of cornea
0.654 0.346 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.653 0.347 0.000
S06.3 Focal brain injury
0.653 0.347 0.000
C56 Malignant neoplasm of ovary
0.653 0.347 0.000
S01.3 Open wound of ear
0.653 0.347 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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