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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs150954431
log Bayes Factor = 0.66025
Chromosome 12   position 125,002,323  (GRCh37) Explore rs150954431 on Ensembl!
Variant rs150954431 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
0.775 0.225 0.000
I60-I69 Cerebrovascular diseases
0.761 0.239 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.744 0.256 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.744 0.256 0.000
# Top node
0.742 0.258 0.000
I30-I52 Other forms of heart disease
0.742 0.258 0.000
S00-S09 Injuries to the head
0.732 0.268 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.714 0.286 0.000
Chapter VIII Diseases of the ear and mastoid process
0.707 0.293 0.000
I80 Phlebitis and thrombophlebitis
0.702 0.298 0.000
S01 Open wound of head
0.699 0.301 0.000
Chapter VI Diseases of the nervous system
0.689 0.311 0.000
I45 Other conduction disorders
0.680 0.320 0.000
I35 Nonrheumatic aortic valve disorders
0.673 0.327 0.000
I63 Cerebral infarction
0.671 0.329 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.670 0.330 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.665 0.335 0.000
I05-I09 Chronic rheumatic heart diseases
0.662 0.338 0.000
G81 Hemiplegia
0.648 0.351 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.648 0.352 0.000
H90-H95 Other disorders of ear
0.647 0.353 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.645 0.355 0.000
S02 Fracture of skull and facial bones
0.644 0.355 0.000
Chapter X Diseases of the respiratory system
0.638 0.362 0.000
G81.9 Hemiplegia, unspecified
0.637 0.363 0.000
I85 Oesophageal varices
0.633 0.367 0.000
J90-J94 Other diseases of pleura
0.624 0.376 0.000
I46 Cardiac arrest
0.623 0.377 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.623 0.377 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.616 0.384 0.000
S80-S89 Injuries to the knee and lower leg
0.615 0.385 0.000
J90 Pleural effusion, not elsewhere classified
0.615 0.385 0.000
S06 Intracranial injury
0.615 0.385 0.000
I61 Intracerebral haemorrhage
0.614 0.386 0.000
S01.0 Open wound of scalp
0.609 0.390 0.000
M20 Acquired deformities of fingers and toes
0.607 0.393 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.607 0.393 0.000
I63.9 Cerebral infarction, unspecified
0.605 0.395 0.000
H65-H75 Diseases of middle ear and mastoid
0.603 0.397 0.000
M20-M25 Other joint disorders
0.601 0.399 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.600 0.400 0.000
S40-S49 Injuries to the shoulder and upper arm
0.599 0.401 0.000
G90-G99 Other disorders of the nervous system
0.598 0.401 0.000
Chapter I Certain infectious and parasitic diseases
0.597 0.403 0.000
M20.4 Other hammer toe(s) (acquired)
0.596 0.404 0.000
I82 Other venous embolism and thrombosis
0.593 0.407 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.593 0.407 0.000
I69 Sequelae of cerebrovascular disease
0.592 0.408 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.589 0.411 0.000
S01.8 Open wound of other parts of head
0.588 0.412 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.586 0.414 0.000
J09-J18 Influenza and pneumonia
0.584 0.416 0.000
T66-T78 Other and unspecified effects of external causes
0.583 0.417 0.000
M20.1 Hallux valgus (acquired)
0.580 0.420 0.000
S01.1 Open wound of eyelid and periocular area
0.578 0.422 0.000
S00 Superficial injury of head
0.577 0.423 0.000
I45.1 Other and unspecified right bundle-branch block
0.577 0.423 0.000
I89.0 Lymphoedema, not elsewhere classified
0.574 0.426 0.000
H92 Otalgia and effusion of ear
0.570 0.430 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.570 0.430 0.000
I67 Other cerebrovascular diseases
0.568 0.432 0.000
I08 Multiple valve diseases
0.563 0.436 0.000
Chapter V Mental and behavioural disorders
0.563 0.437 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.562 0.438 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.561 0.439 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.561 0.439 0.000
I87 Other disorders of veins
0.560 0.440 0.000
I45.5 Other specified heart block
0.560 0.440 0.000
I00-I02 Acute rheumatic fever
0.555 0.444 0.000
H80-H83 Diseases of inner ear
0.554 0.446 0.000
I44 Atrioventricular and left bundle-branch block
0.554 0.446 0.000
I74 Arterial embolism and thrombosis
0.553 0.447 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.553 0.447 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.552 0.448 0.000
I51 Complications and ill-defined descriptions of heart disease
0.551 0.449 0.000
I34 Nonrheumatic mitral valve disorders
0.551 0.449 0.000
I30 Acute pericarditis
0.550 0.450 0.000
I83 Varicose veins of lower extremities
0.550 0.450 0.000
I62 Other nontraumatic intracranial haemorrhage
0.550 0.450 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.549 0.450 0.000
I33 Acute and subacute endocarditis
0.549 0.451 0.000
S20-S29 Injuries to the thorax
0.548 0.452 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.546 0.454 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.546 0.454 0.000
I46.0 Cardiac arrest with successful resuscitation
0.546 0.454 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.545 0.455 0.000
I42 Cardiomyopathy
0.544 0.456 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.544 0.456 0.000
B95-B98 Bacterial, viral and other infectious agents
0.544 0.456 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.544 0.456 0.000
I45.2 Bifascicular block
0.543 0.457 0.000
Chapter XI Diseases of the digestive system
0.542 0.458 0.000
G93 Other disorders of brain
0.542 0.458 0.000
I35.0 Aortic (valve) stenosis
0.541 0.459 0.000
S01.5 Open wound of lip and oral cavity
0.540 0.460 0.000
I20-I25 Ischaemic heart diseases
0.539 0.461 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.538 0.462 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.536 0.464 0.000
I88 Nonspecific lymphadenitis
0.534 0.466 0.000
I81 Portal vein thrombosis
0.534 0.466 0.000
T33-T35 Frostbite
0.533 0.467 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.533 0.467 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.533 0.467 0.000
T00-T07 Injuries involving multiple body regions
0.533 0.467 0.000
S10-S19 Injuries to the neck
0.533 0.467 0.000
T79-T79 Certain early complications of trauma
0.532 0.467 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.532 0.468 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.532 0.468 0.000
I52 Other heart disorders in diseases classified elsewhere
0.532 0.468 0.000
I48 Atrial fibrillation and flutter
0.532 0.468 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.532 0.468 0.000
I41 Myocarditis in diseases classified elsewhere
0.532 0.468 0.000
I40 Acute myocarditis
0.532 0.468 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.532 0.468 0.000
I37 Pulmonary valve disorders
0.532 0.468 0.000
I36 Nonrheumatic tricuspid valve disorders
0.532 0.468 0.000
I32 Pericarditis in diseases classified elsewhere
0.532 0.468 0.000
I85.9 Oesophageal varices without bleeding
0.530 0.470 0.000
S02.0 Fracture of vault of skull
0.529 0.471 0.000
Chapter XXII Codes for special purposes
0.529 0.471 0.000
K04 Diseases of pulp and periapical tissues
0.529 0.471 0.000
H92.0 Otalgia
0.528 0.472 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.527 0.472 0.000
S01.3 Open wound of ear
0.526 0.474 0.000
I31 Other diseases of pericardium
0.526 0.474 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.525 0.475 0.000
S08 Traumatic amputation of part of head
0.525 0.475 0.000
S07 Crushing injury of head
0.525 0.475 0.000
S05 Injury of eye and orbit
0.525 0.475 0.000
S04 Injury of cranial nerves
0.525 0.475 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.525 0.475 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.525 0.475 0.000
M20.5 Other deformities of toe(s) (acquired)
0.525 0.475 0.000
I67.2 Cerebral atherosclerosis
0.524 0.476 0.000
S02.6 Fracture of mandible
0.522 0.478 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.522 0.478 0.000
I35.9 Aortic valve disorder, unspecified
0.522 0.478 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.522 0.478 0.000
I35.1 Aortic (valve) insufficiency
0.520 0.480 0.000
S02.2 Fracture of nasal bones
0.519 0.481 0.000
S70-S79 Injuries to the hip and thigh
0.517 0.483 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.517 0.483 0.000
H66 Suppurative and unspecified otitis media
0.517 0.483 0.000
S90-S99 Injuries to the ankle and foot
0.515 0.485 0.000
H91 Other hearing loss
0.515 0.485 0.000
I86 Varicose veins of other sites
0.514 0.486 0.000
I38 Endocarditis, valve unspecified
0.514 0.486 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.514 0.486 0.000
G70-G73 Diseases of myoneural junction and muscle
0.514 0.486 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.513 0.487 0.000
S50-S59 Injuries to the elbow and forearm
0.512 0.488 0.000
I07 Rheumatic tricuspid valve diseases
0.509 0.491 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.508 0.492 0.000
T39.1 4-Aminophenol derivatives
0.508 0.492 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.507 0.493 0.000
H90 Conductive and sensorineural hearing loss
0.505 0.495 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.503 0.496 0.000
J94 Other pleural conditions
0.502 0.498 0.000
S01.7 Multiple open wounds of head
0.501 0.499 0.000
S01.4 Open wound of cheek and temporomandibular area
0.501 0.499 0.000
S01.2 Open wound of nose
0.501 0.499 0.000
I72 Other aneurysm
0.500 0.500 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.499 0.501 0.000
S06.3 Focal brain injury
0.497 0.503 0.000
H72 Perforation of tympanic membrane
0.496 0.504 0.000
I85.0 Oesophageal varices with bleeding
0.496 0.504 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.496 0.504 0.000
H60-H62 Diseases of external ear
0.495 0.505 0.000
I78 Diseases of capillaries
0.495 0.505 0.000
I45.6 Preexcitation syndrome
0.494 0.506 0.000
S02.1 Fracture of base of skull
0.494 0.506 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.493 0.507 0.000
S00.3 Superficial injury of nose
0.492 0.508 0.000
K70-K77 Diseases of liver
0.490 0.510 0.000
K04.8 Radicular cyst
0.489 0.511 0.000
I45.9 Conduction disorder, unspecified
0.487 0.512 0.000
I45.8 Other specified conduction disorders
0.487 0.512 0.000
I45.4 Nonspecific intraventricular block
0.487 0.512 0.000
I45.3 Trifascicular block
0.487 0.512 0.000
I45.0 Right fascicular block
0.487 0.512 0.000
J00-J06 Acute upper respiratory infections
0.485 0.515 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.485 0.515 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.485 0.515 0.000
I82.8 Embolism and thrombosis of other specified veins
0.485 0.515 0.000
D60-D64 Aplastic and other anaemias
0.485 0.515 0.000
S80 Superficial injury of lower leg
0.484 0.516 0.000
S01.9 Open wound of head, part unspecified
0.483 0.516 0.000
I35.8 Other aortic valve disorders
0.483 0.517 0.000
M24 Other specific joint derangements
0.483 0.517 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.482 0.518 0.000
I63.8 Other cerebral infarction
0.481 0.519 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.481 0.519 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.481 0.519 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.481 0.519 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.481 0.519 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.481 0.519 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.481 0.519 0.000
I47 Paroxysmal tachycardia
0.481 0.519 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.480 0.520 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.480 0.520 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.480 0.520 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.480 0.520 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.480 0.520 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.480 0.520 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.480 0.520 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.480 0.520 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.480 0.520 0.000
T36 Poisoning by systemic antibiotics
0.480 0.520 0.000
G83 Other paralytic syndromes
0.480 0.520 0.000
S06.8 Other intracranial injuries
0.480 0.520 0.000
M91-M94 Chondropathies
0.480 0.520 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.479 0.521 0.000
I60 Subarachnoid haemorrhage
0.477 0.523 0.000
G82 Paraplegia and tetraplegia
0.477 0.523 0.000
G80 Infantile cerebral palsy
0.477 0.523 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.477 0.523 0.000
Chapter VII Diseases of the eye and adnexa
0.475 0.525 0.000
I09 Other rheumatic heart diseases
0.475 0.525 0.000
I06 Rheumatic aortic valve diseases
0.475 0.525 0.000
I05 Rheumatic mitral valve diseases
0.475 0.525 0.000
I77 Other disorders of arteries and arterioles
0.475 0.525 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.473 0.527 0.000
F80-F89 Disorders of psychological development
0.471 0.529 0.000
F30-F39 Mood [affective] disorders
0.471 0.529 0.000
J17 Pneumonia in diseases classified elsewhere
0.470 0.530 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.469 0.531 0.000
T78 Adverse effects, not elsewhere classified
0.468 0.532 0.000
T90 Sequelae of injuries of head
0.467 0.532 0.000
I49 Other cardiac arrhythmias
0.467 0.533 0.000
G96 Other disorders of central nervous system
0.466 0.534 0.000
D72 Other disorders of white blood cells
0.466 0.534 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.466 0.534 0.000
Q50-Q56 Congenital malformations of genital organs
0.466 0.534 0.000
G93.3 Postviral fatigue syndrome
0.465 0.535 0.000
G81.1 Spastic hemiplegia
0.465 0.535 0.000
G81.0 Flaccid hemiplegia
0.465 0.535 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.465 0.535 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.464 0.536 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.464 0.536 0.000
T40.2 Other opioids
0.463 0.537 0.000
H93 Other disorders of ear, not elsewhere classified
0.463 0.537 0.000
H65 Nonsuppurative otitis media
0.463 0.537 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.462 0.537 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.462 0.537 0.000
I89.1 Lymphangitis
0.462 0.537 0.000
M21 Other acquired deformities of limbs
0.462 0.537 0.000
M20.3 Other deformity of hallux (acquired)
0.462 0.538 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.462 0.538 0.000
S02.8 Fractures of other skull and facial bones
0.462 0.538 0.000
S02.7 Multiple fractures involving skull and facial bones
0.462 0.538 0.000
S02.5 Fracture of tooth
0.462 0.538 0.000
S02.3 Fracture of orbital floor
0.462 0.538 0.000
I65.2 Occlusion and stenosis of carotid artery
0.461 0.539 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.461 0.539 0.000
K04.7 Periapical abscess without sinus
0.461 0.539 0.000
S00.9 Superficial injury of head, part unspecified
0.460 0.540 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.460 0.540 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.460 0.540 0.000
I26 Pulmonary embolism
0.460 0.540 0.000
G30-G32 Other degenerative diseases of the nervous system
0.459 0.541 0.000
H81 Disorders of vestibular function
0.458 0.542 0.000
S06.0 Concussion
0.458 0.542 0.000
M86-M90 Other osteopathies
0.457 0.542 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.457 0.543 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.457 0.543 0.000
M50-M54 Other dorsopathies
0.456 0.544 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.455 0.545 0.000
J14 Pneumonia due to Haemophilus influenzae
0.455 0.545 0.000
J93 Pneumothorax
0.455 0.545 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.454 0.546 0.000
M00-M03 Infectious arthropathies
0.453 0.546 0.000
Chapter XX External causes of morbidity and mortality
0.454 0.546 0.000
S06.2 Diffuse brain injury
0.452 0.548 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.452 0.548 0.000
D80-D89 Certain disorders involving the immune mechanism
0.452 0.548 0.000
K04.5 Chronic apical periodontitis
0.452 0.548 0.000
I44.2 Atrioventricular block, complete
0.452 0.548 0.000
A30-A49 Other bacterial diseases
0.451 0.549 0.000
H74 Other disorders of middle ear and mastoid
0.450 0.550 0.000
I27 Other pulmonary heart diseases
0.448 0.551 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.448 0.552 0.000
J60-J70 Lung diseases due to external agents
0.448 0.552 0.000
T39.0 Salicylates
0.448 0.552 0.000
J15.1 Pneumonia due to Pseudomonas
0.447 0.553 0.000
S02.00 Fracture of vault of skull (closed)
0.447 0.553 0.000
I46.1 Sudden cardiac death, so described
0.447 0.553 0.000
T87 Complications peculiar to reattachment and amputation
0.446 0.554 0.000
J15.4 Pneumonia due to other streptococci
0.445 0.555 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.445 0.555 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.444 0.556 0.000
H66.9 Otitis media, unspecified
0.444 0.556 0.000
S42 Fracture of shoulder and upper arm
0.444 0.556 0.000
T85.2 Mechanical complication of intraocular lens
0.444 0.556 0.000
I73 Other peripheral vascular diseases
0.442 0.558 0.000
M60-M63 Disorders of muscles
0.442 0.558 0.000
I21 Acute myocardial infarction
0.442 0.558 0.000
S83.2 Tear of meniscus, current
0.441 0.559 0.000
S89 Other and unspecified injuries of lower leg
0.441 0.559 0.000
S88 Traumatic amputation of lower leg
0.441 0.559 0.000
S87 Crushing injury of lower leg
0.441 0.559 0.000
S86 Injury of muscle and tendon at lower leg level
0.441 0.559 0.000
S85 Injury of blood vessels at lower leg level
0.441 0.559 0.000
S84 Injury of nerves at lower leg level
0.441 0.559 0.000
S32 Fracture of lumbar spine and pelvis
0.441 0.559 0.000
S06.9 Intracranial injury, unspecified
0.441 0.559 0.000
S06.7 Intracranial injury with prolonged coma
0.441 0.559 0.000
S06.4 Epidural haemorrhage
0.441 0.559 0.000
S06.1 Traumatic cerebral oedema
0.441 0.559 0.000
S40 Superficial injury of shoulder and upper arm
0.440 0.560 0.000
I61.8 Other intracerebral haemorrhage
0.440 0.560 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.440 0.560 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.440 0.560 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.440 0.560 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.440 0.560 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.440 0.560 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.440 0.560 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.440 0.560 0.000
I70 Atherosclerosis
0.439 0.560 0.000
S81 Open wound of lower leg
0.439 0.561 0.000
I34.1 Mitral (valve) prolapse
0.439 0.561 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.438 0.561 0.000
I71 Aortic aneurysm and dissection
0.437 0.563 0.000
S51 Open wound of forearm
0.437 0.563 0.000
J95-J99 Other diseases of the respiratory system
0.437 0.563 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.436 0.564 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.435 0.565 0.000
M20.0 Deformity of finger(s)
0.435 0.565 0.000
D55-D59 Haemolytic anaemias
0.435 0.565 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.435 0.565 0.000
I44.0 Atrioventricular block, first degree
0.434 0.566 0.000
S02.60 Fracture of mandible (closed)
0.434 0.566 0.000
M05-M14 Inflammatory polyarthropathies
0.434 0.566 0.000
D72.8 Other specified disorders of white blood cells
0.433 0.567 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.432 0.567 0.000
H70 Mastoiditis and related conditions
0.432 0.567 0.000
H69 Other disorders of Eustachian tube
0.432 0.567 0.000
H68 Eustachian salpingitis and obstruction
0.432 0.567 0.000
H67 Otitis media in diseases classified elsewhere
0.432 0.567 0.000
G91 Hydrocephalus
0.432 0.568 0.000
S09 Other and unspecified injuries of head
0.432 0.568 0.000
G93.0 Cerebral cysts
0.432 0.568 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.431 0.569 0.000
M34 Systemic sclerosis
0.431 0.569 0.000
M33 Dermatopolymyositis
0.431 0.569 0.000
M32 Systemic lupus erythematosus
0.431 0.569 0.000
M30 Polyarteritis nodosa and related conditions
0.431 0.569 0.000
I28 Other diseases of pulmonary vessels
0.430 0.570 0.000
T92 Sequelae of injuries of upper limb
0.430 0.570 0.000
I46.9 Cardiac arrest, unspecified
0.430 0.570 0.000
I51.7 Cardiomegaly
0.430 0.570 0.000
G12 Spinal muscular atrophy and related syndromes
0.429 0.570 0.000
T93 Sequelae of injuries of lower limb
0.429 0.571 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.429 0.571 0.000
S48 Traumatic amputation of shoulder and upper arm
0.429 0.571 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.429 0.571 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.429 0.571 0.000
S44 Injury of nerves at shoulder and upper arm level
0.429 0.571 0.000
S41 Open wound of shoulder and upper arm
0.429 0.571 0.000
S47 Crushing injury of shoulder and upper arm
0.429 0.571 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.429 0.571 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.429 0.571 0.000
G90 Disorders of autonomic nervous system
0.429 0.571 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.429 0.571 0.000
G92 Toxic encephalopathy
0.429 0.571 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.429 0.571 0.000
S02.20 Fracture of nasal bones (closed)
0.428 0.572 0.000
B99-B99 Other infectious diseases
0.428 0.572 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.428 0.572 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.428 0.572 0.000
B65-B83 Helminthiases
0.428 0.572 0.000
B50-B64 Protozoal diseases
0.428 0.572 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.428 0.572 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.428 0.572 0.000
A80-A89 Viral infections of the central nervous system
0.428 0.572 0.000
A75-A79 Rickettsioses
0.428 0.572 0.000
A70-A74 Other diseases caused by chlamydiae
0.428 0.572 0.000
A65-A69 Other spirochaetal diseases
0.428 0.572 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.428 0.572 0.000
A20-A28 Certain zoonotic bacterial diseases
0.428 0.572 0.000
A15-A19 Tuberculosis
0.428 0.572 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.427 0.573 0.000
H90.3 Sensorineural hearing loss, bilateral
0.426 0.574 0.000
I51.9 Heart disease, unspecified
0.425 0.574 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.425 0.575 0.000
I82.3 Embolism and thrombosis of renal vein
0.425 0.575 0.000
I82.2 Embolism and thrombosis of vena cava
0.425 0.575 0.000
I82.1 Thrombophlebitis migrans
0.425 0.575 0.000
I82.0 Budd-Chiari syndrome
0.425 0.575 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.425 0.575 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.425 0.575 0.000
T39.4 Antirheumatics, not elsewhere classified
0.425 0.575 0.000
T39.2 Pyrazolone derivatives
0.425 0.575 0.000
K04.6 Periapical abscess with sinus
0.425 0.575 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.424 0.575 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.424 0.575 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.424 0.575 0.000
T18 Foreign body in alimentary tract
0.424 0.576 0.000
S20 Superficial injury of thorax
0.424 0.576 0.000
F99-F99 Unspecified mental disorder
0.424 0.576 0.000
M40-M43 Deforming dorsopathies
0.424 0.576 0.000
S00.1 Contusion of eyelid and periocular area
0.423 0.577 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.423 0.577 0.000
B25-B34 Other viral diseases
0.423 0.577 0.000
K72 Hepatic failure, not elsewhere classified
0.423 0.577 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.423 0.577 0.000
T98 Sequelae of other and unspecified effects of external causes
0.422 0.578 0.000
T95 Sequelae of burns, corrosions and frostbite
0.422 0.578 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.422 0.578 0.000
T91 Sequelae of injuries of neck and trunk
0.422 0.578 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.422 0.578 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.422 0.578 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.421 0.579 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.420 0.580 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.420 0.580 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.420 0.580 0.000
I65.1 Occlusion and stenosis of basilar artery
0.420 0.580 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.420 0.580 0.000
G93.8 Other specified disorders of brain
0.420 0.580 0.000
H91.9 Hearing loss, unspecified
0.420 0.580 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.420 0.580 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.419 0.581 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.419 0.581 0.000
J12 Viral pneumonia, not elsewhere classified
0.419 0.581 0.000
J11 Influenza, virus not identified
0.419 0.581 0.000
J10 Influenza due to identified influenza virus
0.419 0.581 0.000
J09 Influenza due to certain identified influenza virus
0.419 0.581 0.000
T86 Failure and rejection of transplanted organs and tissues
0.418 0.582 0.000
T75 Effects of other external causes
0.418 0.582 0.000
T74 Maltreatment syndromes
0.418 0.582 0.000
T73 Effects of other deprivation
0.418 0.582 0.000
T70 Effects of air pressure and water pressure
0.418 0.582 0.000
T69 Other effects of reduced temperature
0.418 0.582 0.000
T67 Effects of heat and light
0.418 0.582 0.000
T71 Asphyxiation
0.418 0.582 0.000
T68 Hypothermia
0.418 0.582 0.000
T66 Unspecified effects of radiation
0.418 0.582 0.000
M80-M85 Disorders of bone density and structure
0.418 0.582 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.417 0.583 0.000
K09 Cysts of oral region, not elsewhere classified
0.417 0.583 0.000
B15-B19 Viral hepatitis
0.416 0.584 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.416 0.584 0.000
Q60-Q64 Congenital malformations of the urinary system
0.415 0.585 0.000
I87.8 Other specified disorders of veins
0.415 0.585 0.000
J91 Pleural effusion in conditions classified elsewhere
0.415 0.585 0.000
S00.7 Multiple superficial injuries of head
0.414 0.586 0.000
S00.5 Superficial injury of lip and oral cavity
0.414 0.586 0.000
S00.4 Superficial injury of ear
0.414 0.586 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.414 0.586 0.000
I30.9 Acute pericarditis, unspecified
0.413 0.587 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.413 0.587 0.000
I22 Subsequent myocardial infarction
0.413 0.587 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.413 0.587 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.411 0.589 0.000
I33.0 Acute and subacute infective endocarditis
0.411 0.589 0.000
B35-B49 Mycoses
0.411 0.589 0.000
I31.9 Disease of pericardium, unspecified
0.410 0.590 0.000
H40-H42 Glaucoma
0.409 0.591 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.409 0.591 0.000
H92.2 Otorrhagia
0.409 0.591 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.408 0.591 0.000
Q80-Q89 Other congenital malformations
0.408 0.591 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.408 0.591 0.000
Q35-Q37 Cleft lip and cleft palate
0.408 0.591 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.408 0.591 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.408 0.591 0.000
Q00-Q07 Congenital malformations of the nervous system
0.408 0.591 0.000
S82 Fracture of lower leg, including ankle
0.408 0.591 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.408 0.592 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.407 0.592 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.407 0.592 0.000
I67.5 Moyamoya disease
0.407 0.592 0.000
I67.4 Hypertensive encephalopathy
0.407 0.592 0.000
I67.3 Progressive vascular leukoencephalopathy
0.407 0.592 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.407 0.592 0.000
I08.0 Disorders of both mitral and aortic valves
0.407 0.593 0.000
D63.0 Anaemia in neoplastic disease
0.407 0.593 0.000
G61 Inflammatory polyneuropathy
0.407 0.593 0.000
K01 Embedded and impacted teeth
0.406 0.594 0.000
F81 Specific developmental disorders of scholastic skills
0.405 0.595 0.000
I08.9 Multiple valve disease, unspecified
0.404 0.596 0.000
I08.8 Other multiple valve diseases
0.404 0.596 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.404 0.596 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.404 0.596 0.000
F70-F79 Mental retardation
0.404 0.596 0.000
F60-F69 Disorders of adult personality and behaviour
0.404 0.596 0.000
K08 Other disorders of teeth and supporting structures
0.404 0.596 0.000
K81 Cholecystitis
0.404 0.596 0.000
M31 Other necrotising vasculopathies
0.403 0.597 0.000
M65-M68 Disorders of synovium and tendon
0.403 0.597 0.000
D50-D53 Nutritional anaemias
0.402 0.598 0.000
S60-S69 Injuries to the wrist and hand
0.402 0.598 0.000
I87.9 Disorder of vein, unspecified
0.402 0.598 0.000
I87.1 Compression of vein
0.402 0.598 0.000
I87.0 Postphlebitic syndrome
0.402 0.598 0.000
J94.2 Haemothorax
0.401 0.599 0.000
S06.5 Traumatic subdural haemorrhage
0.401 0.599 0.000
G93.6 Cerebral oedema
0.401 0.599 0.000
T14 Injury of unspecified body region
0.400 0.600 0.000
I69.3 Sequelae of cerebral infarction
0.400 0.600 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.400 0.600 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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