TreeWAS – Variant ID: rs1513326

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
Chapter I Certain infectious and parasitic diseases	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.999	0.001
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.998	0.002
A30-A49 Other bacterial diseases	0.997	0.003
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.996	0.004
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.995	0.005
Chapter VIII Diseases of the ear and mastoid process	0.994	0.006
A41 Other septicaemia	0.993	0.007
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.992	0.008
D68 Other coagulation defects	0.991	0.009
H65-H75 Diseases of middle ear and mastoid	0.990	0.010
S50-S59 Injuries to the elbow and forearm	0.986	0.014
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.984	0.016
T90 Sequelae of injuries of head	0.984	0.016
A41.5 Septicaemia due to other Gram-negative organisms	0.980	0.020
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.976	0.024
S52 Fracture of forearm	0.967	0.033
T91 Sequelae of injuries of neck and trunk	0.965	0.035
D68.9 Coagulation defect, unspecified	0.965	0.035
S30 Superficial injury of abdomen, lower back and pelvis	0.958	0.042
A41.0 Septicaemia due to Staphylococcus aureus	0.952	0.048
H74 Other disorders of middle ear and mastoid	0.952	0.048
H73 Other disorders of tympanic membrane	0.950	0.050
M40-M43 Deforming dorsopathies	0.950	0.050
M20-M25 Other joint disorders	0.945	0.055
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.945	0.055
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.942	0.058
D68.5 Primary Thrombophilia	0.937	0.063
T90.2 Sequelae of fracture of skull and facial bones	0.936	0.064
M45-M49 Spondylopathies	0.936	0.064
M05-M14 Inflammatory polyarthropathies	0.933	0.067
S40-S49 Injuries to the shoulder and upper arm	0.928	0.072
M24 Other specific joint derangements	0.927	0.073
B95-B98 Bacterial, viral and other infectious agents	0.923	0.077
T92 Sequelae of injuries of upper limb	0.923	0.077
M47 Spondylosis	0.922	0.078
S10-S19 Injuries to the neck	0.921	0.079
M43 Other deforming dorsopathies	0.921	0.079
H73.8 Other specified disorders of tympanic membrane	0.914	0.086
S00-S09 Injuries to the head	0.911	0.089
T91.3 Sequelae of injury of spinal cord	0.910	0.090
H74.8 Other specified disorders of middle ear and mastoid	0.905	0.095
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.903	0.097
Chapter II Neoplasms	0.903	0.097
S52.2 Fracture of shaft of ulna	0.899	0.101
D68.8 Other specified coagulation defects	0.897	0.103
M22 Disorders of patella	0.897	0.103
T81 Complications of procedures, not elsewhere classified	0.897	0.103
S06 Intracranial injury	0.894	0.106
T90.5 Sequelae of intracranial injury	0.894	0.106
M70-M79 Other soft tissue disorders	0.893	0.107
T83.1 Mechanical complication of other urinary devices and implants	0.887	0.113
M43.1 Spondylolisthesis	0.886	0.114
M86-M90 Other osteopathies	0.885	0.115
B00 Herpesviral [herpes simplex] infections	0.883	0.117
T81.4 Infection following a procedure, not elsewhere classified	0.882	0.118
B25-B34 Other viral diseases	0.882	0.118
M80-M85 Disorders of bone density and structure	0.881	0.119
A41.1 Septicaemia due to other specified staphylococcus	0.879	0.121
S30.0 Contusion of lower back and pelvis	0.876	0.124
M24.2 Disorder of ligament	0.871	0.129
T85 Complications of other internal prosthetic devices, implants and grafts	0.868	0.132
C91 Lymphoid leukaemia	0.866	0.134
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.865	0.135
M43.17 Spondylolisthesis (Lumbosacral region)	0.865	0.135
D55-D59 Haemolytic anaemias	0.860	0.140
C81 Hodgkin's disease	0.860	0.140
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.859	0.141
M60-M63 Disorders of muscles	0.858	0.142
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.857	0.143
Chapter XX External causes of morbidity and mortality	0.853	0.147
B50-B64 Protozoal diseases	0.851	0.149
T80 Complications following infusion, transfusion and therapeutic injection	0.847	0.153
S32 Fracture of lumbar spine and pelvis	0.844	0.156
C91.1 Chronic lymphocytic leukaemia	0.842	0.158
M47.1 Other spondylosis with myelopathy	0.842	0.158
A50-A64 Infections with a predominantly sexual mode of transmission	0.841	0.159
M24.5 Contracture of joint	0.841	0.159
T90.8 Sequelae of other specified injuries of head	0.840	0.160
T87 Complications peculiar to reattachment and amputation	0.839	0.161
M47.8 Other spondylosis	0.838	0.162
B97 Viral agents as the cause of diseases classified to other chapters	0.835	0.165
T15-T19 Effects of foreign body entering through natural orifice	0.834	0.166
B00.1 Herpesviral vesicular dermatitis	0.830	0.170
H72 Perforation of tympanic membrane	0.829	0.171
S52.6 Fracture of lower end of both ulna and radius	0.829	0.171
M72 Fibroblastic disorders	0.828	0.172
M47.9 Spondylosis, unspecified	0.827	0.173
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.826	0.174
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.826	0.174
S52.20 Fracture of shaft of ulna (closed)	0.822	0.178
C81.9 Hodgkin's disease, unspecified	0.820	0.180
M24.4 Recurrent dislocation and subluxation of joint	0.819	0.181
H69 Other disorders of Eustachian tube	0.816	0.184
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.812	0.188
M22.2 Patellofemoral disorders	0.812	0.188
B02 Zoster [herpes zoster]	0.812	0.188
B27 Infectious mononucleosis	0.811	0.189
S52.5 Fracture of lower end of radius	0.811	0.189
Q80-Q89 Other congenital malformations	0.809	0.191
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.808	0.192
S06.2 Diffuse brain injury	0.807	0.193
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.802	0.198
S42 Fracture of shoulder and upper arm	0.802	0.198
S06.5 Traumatic subdural haemorrhage	0.801	0.199
S52.4 Fracture of shafts of both ulna and radius	0.800	0.200
M79 Other soft tissue disorders, not elsewhere classified	0.800	0.200
T91.2 Sequelae of other fracture of thorax and pelvis	0.800	0.200
T91.1 Sequelae of fracture of spine	0.798	0.202
M85 Other disorders of bone density and structure	0.795	0.205
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.795	0.205
D80-D89 Certain disorders involving the immune mechanism	0.795	0.205
T92.2 Sequelae of fracture at wrist and hand level	0.794	0.206
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.794	0.206
M89 Other disorders of bone	0.793	0.207
T81.3 Disruption of operation wound, not elsewhere classified	0.793	0.207
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.791	0.209
M22.4 Chondromalacia patellae	0.790	0.210
T86 Failure and rejection of transplanted organs and tissues	0.788	0.211
B65-B83 Helminthiases	0.787	0.213
S80-S89 Injuries to the knee and lower leg	0.786	0.214
M13 Other arthritis	0.785	0.215
M10 Gout	0.783	0.217
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.778	0.222
S32.0 Fracture of lumbar vertebra	0.778	0.222
S54 Injury of nerves at forearm level	0.777	0.223
H65 Nonsuppurative otitis media	0.777	0.223
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.776	0.224
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.776	0.224
D68.6 Other Thrombophilia	0.775	0.225
C83 Diffuse non-Hodgkin's lymphoma	0.775	0.225
H74.0 Tympanosclerosis	0.775	0.225
M24.27 Disorder of ligament (Ankle and foot)	0.774	0.226
H66 Suppurative and unspecified otitis media	0.772	0.228
Q38-Q45 Other congenital malformations of the digestive system	0.770	0.230
S12 Fracture of neck	0.770	0.230
A49 Bacterial infection of unspecified site	0.770	0.230
M21 Other acquired deformities of limbs	0.768	0.232
A40 Streptococcal septicaemia	0.767	0.233
T94 Sequelae of injuries involving multiple and unspecified body regions	0.767	0.233
M86 Osteomyelitis	0.763	0.236
S50 Superficial injury of forearm	0.762	0.238
S46 Injury of muscle and tendon at shoulder and upper arm level	0.762	0.238
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.761	0.239
B27.9 Infectious mononucleosis, unspecified	0.761	0.239
B90-B94 Sequelae of infectious and parasitic diseases	0.760	0.240
S80 Superficial injury of lower leg	0.759	0.241
S02 Fracture of skull and facial bones	0.759	0.241
M62 Other disorders of muscle	0.757	0.243
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.756	0.244
S40 Superficial injury of shoulder and upper arm	0.756	0.244
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.756	0.244
M47.80 Other spondylosis (Multiple sites in spine)	0.755	0.245
A46 Erysipelas	0.754	0.246
A65-A69 Other spirochaetal diseases	0.754	0.246
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.754	0.246
M11 Other crystal arthropathies	0.753	0.247
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.752	0.248
S52.8 Fracture of other parts of forearm	0.751	0.249
H60-H62 Diseases of external ear	0.750	0.250
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.749	0.251
S14 Injury of nerves and spinal cord at neck level	0.748	0.252
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.748	0.252
S52.1 Fracture of upper end of radius	0.748	0.252
M89.9 Disorder of bone, unspecified	0.746	0.254
S06.20 Diffuse brain injury (without open intracranial wound)	0.745	0.255
M47.96 Spondylosis, unspecified (Lumbar region)	0.745	0.255
C51-C58 Malignant neoplasms of female genital organs	0.744	0.256
H74.4 Polyp of middle ear	0.742	0.258
S06.3 Focal brain injury	0.741	0.259
A15-A19 Tuberculosis	0.738	0.262
S52.21 Fracture of shaft of ulna (open)	0.738	0.262
H73.9 Disorder of tympanic membrane, unspecified	0.737	0.263
S31 Open wound of abdomen, lower back and pelvis	0.737	0.263
M47.12 Other spondylosis with myelopathy (Cervical region)	0.736	0.264
S51 Open wound of forearm	0.736	0.264
M91-M94 Chondropathies	0.736	0.264
M43.0 Spondylolysis	0.735	0.265
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.735	0.265
M30 Polyarteritis nodosa and related conditions	0.735	0.265
S09 Other and unspecified injuries of head	0.734	0.266
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.734	0.266
H74.9 Disorder of middle ear and mastoid, unspecified	0.733	0.267
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.732	0.268
T79-T79 Certain early complications of trauma	0.732	0.268
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.732	0.268
A80-A89 Viral infections of the central nervous system	0.731	0.269
S32.00 Fracture of lumbar vertebra (closed)	0.731	0.269
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.730	0.270
S90-S99 Injuries to the ankle and foot	0.728	0.272
M00-M03 Infectious arthropathies	0.728	0.272
Y83.9 Surgical procedure, unspecified	0.728	0.272
Q20-Q28 Congenital malformations of the circulatory system	0.727	0.273
H90-H95 Other disorders of ear	0.727	0.273
S20-S29 Injuries to the thorax	0.726	0.274
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.726	0.274
M31 Other necrotising vasculopathies	0.725	0.275
M79.0 Rheumatism, unspecified	0.724	0.276
S36 Injury of intra-abdominal organs	0.723	0.277
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.722	0.278
M07 Psoriatic and enteropathic arthropathies	0.721	0.279
M06 Other rheumatoid arthritis	0.718	0.282
T00-T07 Injuries involving multiple body regions	0.717	0.282
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
B85-B89 Pediculosis, acariasis and other infestations	0.717	0.283
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.717	0.283
A75-A79 Rickettsioses	0.717	0.283
A70-A74 Other diseases caused by chlamydiae	0.717	0.283
A20-A28 Certain zoonotic bacterial diseases	0.717	0.283
M24.54 Contracture of joint (Hand)	0.717	0.283
T95 Sequelae of burns, corrosions and frostbite	0.716	0.284
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.716	0.284
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.716	0.284
M84 Disorders of continuity of bone	0.716	0.284
D50-D53 Nutritional anaemias	0.716	0.284
A48 Other bacterial diseases, not elsewhere classified	0.715	0.285
A44 Bartonellosis	0.715	0.285
A43 Nocardiosis	0.715	0.285
A42 Actinomycosis	0.715	0.285
A39 Meningococcal infection	0.715	0.285
A37 Whooping cough	0.715	0.285
A36 Diphtheria	0.715	0.285
A32 Listeriosis	0.715	0.285
A31 Infection due to other mycobacteria	0.715	0.285
A30 Leprosy [Hansen's disease]	0.715	0.285
A38 Scarlet fever	0.715	0.285
A35 Other tetanus	0.715	0.285
A34 Obstetrical tetanus	0.715	0.285
A33 Tetanus neonatorum	0.715	0.285
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.715	0.285
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.714	0.286
T83.2 Mechanical complication of graft of urinary organ	0.714	0.286
V80-V89 Other land transport accidents	0.713	0.287
C84 Peripheral and cutaneous T-cell lymphomas	0.713	0.287
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.713	0.287
D66 Hereditary factor VIII deficiency	0.712	0.288
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.712	0.288
A41.4 Septicaemia due to anaerobes	0.712	0.288
A41.3 Septicaemia due to Haemophilus influenzae	0.712	0.288
S80.9 Superficial injury of lower leg, unspecified	0.712	0.288
D67 Hereditary factor IX deficiency	0.711	0.288
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.711	0.288
T81.7 Vascular complications following a procedure, not elsewhere classified	0.711	0.289
M43.12 Spondylolisthesis (Cervical region)	0.711	0.289
D68.4 Acquired coagulation factor deficiency	0.710	0.290
D68.1 Hereditary factor XI deficiency	0.710	0.290
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.710	0.290
H68 Eustachian salpingitis and obstruction	0.710	0.290
H67 Otitis media in diseases classified elsewhere	0.710	0.290
D56 Thalassaemia	0.709	0.291
M24.21 Disorder of ligament (Shoulder region)	0.709	0.291
B20-B24 Human immunodeficiency virus [HIV] disease	0.708	0.292
D68.2 Hereditary deficiency of other clotting factors	0.708	0.292
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.708	0.292
S52.60 Fracture of lower end of both ulna and radius (closed)	0.708	0.292
S59 Other and unspecified injuries of forearm	0.707	0.293
S58 Traumatic amputation of forearm	0.707	0.293
S57 Crushing injury of forearm	0.707	0.293
S55 Injury of blood vessels at forearm level	0.707	0.293
M43.6 Torticollis	0.706	0.294
D59 Acquired haemolytic anaemia	0.706	0.294
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.705	0.295
S37 Injury of urinary and pelvic organs	0.705	0.295
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.705	0.295
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.705	0.295
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.705	0.295
T90.3 Sequelae of injury of cranial nerves	0.705	0.295
T90.1 Sequelae of open wound of head	0.705	0.295
T90.0 Sequelae of superficial injury of head	0.705	0.295
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.705	0.295
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.704	0.296
B59 Pneumocystosis	0.704	0.296
M24.26 Disorder of ligament (Lower leg)	0.703	0.297
D37-D48 Neoplasms of uncertain or unknown behaviour	0.703	0.297
S42.0 Fracture of clavicle	0.703	0.297
S13.4 Sprain and strain of cervical spine	0.702	0.298
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.702	0.298
S30.1 Contusion of abdominal wall	0.701	0.299
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.701	0.299
Q85 Phakomatoses, not elsewhere classified	0.700	0.300
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.699	0.300
S06.8 Other intracranial injuries	0.699	0.301
T92.0 Sequelae of open wound of upper limb	0.699	0.301
M79.6 Pain in limb	0.699	0.301
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.697	0.303
S49 Other and unspecified injuries of shoulder and upper arm	0.697	0.303
W50-W64 Exposure to animate mechanical forces	0.694	0.306
S52.9 Fracture of forearm, part unspecified	0.694	0.306
S52.3 Fracture of shaft of radius	0.694	0.306
H72.0 Central perforation of tympanic membrane	0.693	0.307
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.693	0.307
M82 Osteoporosis in diseases classified elsewhere	0.693	0.307
S52.7 Multiple fractures of forearm	0.692	0.308
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.692	0.308
T91.4 Sequelae of injury of intrathoracic organs	0.692	0.308
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.692	0.308
M14 Arthropathies in other diseases classified elsewhere	0.691	0.308
M49 Spondylopathies in diseases classified elsewhere	0.691	0.309
H72.9 Perforation of tympanic membrane, unspecified	0.690	0.310
M24.28 Disorder of ligament (Other)	0.690	0.310
Chapter IV Endocrine, nutritional and metabolic diseases	0.690	0.310
T91.9 Sequelae of unspecified injury of neck and trunk	0.689	0.311
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.687	0.313
S30.2 Contusion of external genital organs	0.687	0.313
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.686	0.314
M79.60 Pain in limb (Multiple sites)	0.686	0.314
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.685	0.315
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.685	0.315
D89.2 Hypergammaglobulinaemia, unspecified	0.683	0.317
H74.2 Discontinuity and dislocation of ear ossicles	0.682	0.318
H74.1 Adhesive middle ear disease	0.682	0.318
B02.9 Zoster without complication	0.682	0.318
Chapter V Mental and behavioural disorders	0.681	0.319
H73.1 Chronic myringitis	0.681	0.319
H73.0 Acute myringitis	0.681	0.319
B35-B49 Mycoses	0.681	0.319
M42 Spinal osteochondrosis	0.681	0.319
M40 Kyphosis and lordosis	0.681	0.319
S52.40 Fracture of shafts of both ulna and radius (closed)	0.681	0.319
H69.9 Eustachian tube disorder, unspecified	0.680	0.320
C64-C68 Malignant neoplasms of urinary tract	0.680	0.320
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.680	0.320
T20-T25 Burns and corrosions of external body surface, specified by site	0.679	0.321
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.679	0.321
Y49 Psychotropic drugs, not elsewhere classified	0.679	0.321
T83.3 Mechanical complication of intra-uterine contraceptive device	0.678	0.322
B01 Varicella [chickenpox]	0.678	0.322
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.678	0.322
M32 Systemic lupus erythematosus	0.678	0.322
B06 Rubella [German measles]	0.678	0.322
B05 Measles	0.678	0.322
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.678	0.322
B04 Monkeypox	0.678	0.322
B03 Smallpox	0.678	0.322
T87.4 Infection of amputation stump	0.677	0.323
B50 Plasmodium falciparum malaria	0.677	0.323
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.676	0.324
M10.9 Gout, unspecified	0.676	0.324
S41 Open wound of shoulder and upper arm	0.675	0.324
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.675	0.324
Q35-Q37 Cleft lip and cleft palate	0.675	0.324
Q30-Q34 Congenital malformations of the respiratory system	0.675	0.324
M85.8 Other specified disorders of bone density and structure	0.675	0.325
S06.9 Intracranial injury, unspecified	0.675	0.325
Q00-Q07 Congenital malformations of the nervous system	0.675	0.325
C95 Leukaemia of unspecified cell type	0.674	0.326
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.674	0.326
M76 Enthesopathies of lower limb, excluding foot	0.674	0.326
M47.86 Other spondylosis (Lumbar region)	0.673	0.327
S06.6 Traumatic subarachnoid haemorrhage	0.673	0.327
B00.9 Herpesviral infection, unspecified	0.672	0.328
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.672	0.328
M06.0 Seronegative rheumatoid arthritis	0.672	0.328
S02.3 Fracture of orbital floor	0.671	0.328
S10 Superficial injury of neck	0.671	0.329
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.671	0.329
S11 Open wound of neck	0.670	0.330
H66.3 Other chronic suppurative otitis media	0.670	0.330
M12 Other specific arthropathies	0.669	0.331
M09 Juvenile arthritis in diseases classified elsewhere	0.669	0.331
M08 Juvenile arthritis	0.669	0.331
T17 Foreign body in respiratory tract	0.669	0.331
H65.3 Chronic mucoid otitis media	0.669	0.331
Y83.3 Surgical operation with formation of external stoma	0.668	0.332
S60-S69 Injuries to the wrist and hand	0.667	0.333
S32.1 Fracture of sacrum	0.666	0.334
C81.1 Nodular sclerosis	0.666	0.334
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.666	0.334
M85.6 Other cyst of bone	0.666	0.334
S48 Traumatic amputation of shoulder and upper arm	0.665	0.335
S45 Injury of blood vessels at shoulder and upper arm level	0.665	0.335
S44 Injury of nerves at shoulder and upper arm level	0.665	0.335
S47 Crushing injury of shoulder and upper arm	0.665	0.335
Q76 Congenital malformations of spine and bony thorax	0.665	0.335
M71 Other bursopathies	0.665	0.335
S56 Injury of muscle and tendon at forearm level	0.665	0.335
M24.9 Joint derangement, unspecified	0.664	0.336
M24.7 Protrusio acetabuli	0.664	0.336
M24.6 Ankylosis of joint	0.664	0.336
V95-V97 Air and space transport accidents	0.664	0.336
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.664	0.336
T18 Foreign body in alimentary tract	0.663	0.337
S52.51 Fracture of lower end of radius (open)	0.663	0.337
M24.56 Contracture of joint (Lower leg)	0.662	0.338
Q60-Q64 Congenital malformations of the urinary system	0.662	0.338
T92.8 Sequelae of other specified injuries of upper limb	0.662	0.338
T92.4 Sequelae of injury of nerve of upper limb	0.662	0.338
C07 Malignant neoplasm of parotid gland	0.661	0.338
M47.0 Anterior spinal and vertebral artery compression syndromes	0.661	0.339
Y84.2 Radiological procedure and radiotherapy	0.661	0.339
T93 Sequelae of injuries of lower limb	0.661	0.339
S17 Crushing injury of neck	0.660	0.340
S15 Injury of blood vessels at neck level	0.660	0.340
S18 Traumatic amputation at neck level	0.660	0.340
S16 Injury of muscle and tendon at neck level	0.660	0.340
E00-E07 Disorders of thyroid gland	0.660	0.340
M43.9 Deforming dorsopathy, unspecified	0.660	0.340
M43.8 Other specified deforming dorsopathies	0.660	0.340
M43.5 Other recurrent vertebral subluxation	0.660	0.340
M43.4 Other recurrent atlantoaxial subluxation	0.660	0.340
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.660	0.340
M43.2 Other fusion of spine	0.660	0.340
Q50-Q56 Congenital malformations of genital organs	0.660	0.340
S06.4 Epidural haemorrhage	0.660	0.340
T90.9 Sequelae of unspecified injury of head	0.660	0.340
C55 Malignant neoplasm of uterus, part unspecified	0.659	0.341
M24.57 Contracture of joint (Ankle and foot)	0.659	0.341
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.658	0.341
M62.8 Other specified disorders of muscle	0.656	0.344
M33 Dermatopolymyositis	0.656	0.344
S05 Injury of eye and orbit	0.655	0.344
X58-X59 Accidental exposure to other and unspecified factors	0.655	0.344
B25 Cytomegaloviral disease	0.655	0.345
M22.8 Other disorders of patella	0.654	0.346
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.654	0.346
H70 Mastoiditis and related conditions	0.654	0.346
T81.9 Unspecified complication of procedure	0.653	0.347
S08 Traumatic amputation of part of head	0.653	0.347
S07 Crushing injury of head	0.653	0.347
S04 Injury of cranial nerves	0.653	0.347
S03 Dislocation, sprain and strain of joints and ligaments of head	0.653	0.347
B99-B99 Other infectious diseases	0.652	0.348
C11 Malignant neoplasm of nasopharynx	0.652	0.348
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.651	0.348
M47.2 Other spondylosis with radiculopathy	0.650	0.350
M72.1 Knuckle pads	0.650	0.350
A41.2 Septicaemia due to unspecified staphylococcus	0.649	0.351
Q89 Other congenital malformations, not elsewhere classified	0.649	0.351
T90.4 Sequelae of injury of eye and orbit	0.648	0.352
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.648	0.352
C94 Other leukaemias of specified cell type	0.648	0.352
C93 Monocytic leukaemia	0.648	0.352
C86 Other specified types of T/NK-cell lymphoma	0.648	0.352
C40-C41 Malignant neoplasms of bone and articular cartilage	0.648	0.352
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.646	0.353
C83.3 Large cell (diffuse)	0.646	0.354
T91.8 Sequelae of other specified injuries of neck and trunk	0.645	0.355
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.644	0.355
T87.6 Other and unspecified complications of amputation stump	0.644	0.356
M22.1 Recurrent subluxation of patella	0.643	0.357
M22.9 Disorder of patella, unspecified	0.643	0.357
M22.3 Other derangements of patella	0.643	0.357
M22.0 Recurrent dislocation of patella	0.643	0.357
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.643	0.357
T83.0 Mechanical complication of urinary (indwelling) catheter	0.643	0.357
S20 Superficial injury of thorax	0.643	0.357
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.643	0.357
T86.8 Failure and rejection of other transplanted organs and tissues	0.642	0.358
S06.7 Intracranial injury with prolonged coma	0.641	0.359
S06.1 Traumatic cerebral oedema	0.641	0.359
M73 Soft tissue disorders in diseases classified elsewhere	0.640	0.359
T92.1 Sequelae of fracture of arm	0.640	0.359
D39.1 Ovary	0.640	0.360
S80.8 Other superficial injuries of lower leg	0.640	0.360
M79.5 Residual foreign body in soft tissue	0.639	0.361
Y49.5 Other antipsychotics and neuroleptics	0.639	0.361
S52.50 Fracture of lower end of radius (closed)	0.639	0.361
C43-C44 Melanoma and other malignant neoplasms of skin	0.637	0.363
S52.61 Fracture of lower end of both ulna and radius (open)	0.637	0.363
A60 Anogenital herpesviral [herpes simplex] infections	0.637	0.363
M86.9 Osteomyelitis, unspecified	0.635	0.365
M43.19 Spondylolisthesis (Site unspecified)	0.635	0.365
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.635	0.365
M43.15 Spondylolisthesis (Thoracolumbar region)	0.635	0.365
M43.14 Spondylolisthesis (Thoracic region)	0.635	0.365
M43.13 Spondylolisthesis (Cervicothoracic region)	0.635	0.365
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.635	0.365
M43.10 Spondylolisthesis (Multiple sites in spine)	0.635	0.365
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.635	0.365
M24.51 Contracture of joint (Shoulder region)	0.635	0.365
C91.0 Acute lymphoblastic leukaemia	0.634	0.365
M13.0 Polyarthritis, unspecified	0.634	0.366
B80 Enterobiasis	0.634	0.366
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.634	0.366
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.633	0.367
T87.3 Neuroma of amputation stump	0.633	0.367
B00.8 Other forms of herpesviral infection	0.633	0.367
B00.7 Disseminated herpesviral disease	0.633	0.367
B00.4 Herpesviral encephalitis	0.633	0.367
B00.3 Herpesviral meningitis	0.633	0.367
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.633	0.367
B00.0 Eczema herpeticum	0.633	0.367
M70 Soft tissue disorders related to use, overuse and pressure	0.632	0.367
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.632	0.368
B33 Other viral diseases, not elsewhere classified	0.632	0.368
B30 Viral conjunctivitis	0.632	0.368
B26 Mumps	0.632	0.368
S42.00 Fracture of clavicle (closed)	0.632	0.368
E05 Thyrotoxicosis [hyperthyroidism]	0.632	0.368
M83 Adult osteomalacia	0.632	0.368
S06.30 Focal brain injury (without open intracranial wound)	0.632	0.368
M88 Paget's disease of bone [osteitis deformans]	0.632	0.368
T92.9 Sequelae of unspecified injury of upper limb	0.631	0.368
S12.9 Fracture of neck, part unspecified	0.631	0.369
B02.3 Zoster ocular disease	0.631	0.369

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations