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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs154978
log Bayes Factor = 112.909
Chromosome 6   position 32,899,296  (GRCh37) Explore rs154978 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.001 0.999
E14 Unspecified diabetes mellitus
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.003 0.997
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.008 0.992
E10.2 With renal complications
0.000 0.012 0.988
E11 Non-insulin-dependent diabetes mellitus
0.000 0.012 0.988
E14.3 With ophthalmic complications
0.000 0.013 0.987
E10.8 With unspecified complications
0.000 0.017 0.983
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.022 0.978
E14.9 Without complications
0.000 0.026 0.974
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.026 0.974
E10.0 With coma
0.000 0.029 0.971
M35.3 Polymyalgia rheumatica
0.000 0.030 0.970
E10.5 With peripheral circulatory complications
0.000 0.033 0.967
J33.0 Polyp of nasal cavity
0.000 0.034 0.966
J33 Nasal polyp
0.000 0.039 0.961
J33.9 Nasal polyp, unspecified
0.000 0.048 0.952
E11.9 Without complications
0.000 0.078 0.922
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.092 0.908
K90 Intestinal malabsorption
0.000 0.097 0.903
E06 Thyroiditis
0.000 0.101 0.899
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.106 0.894
H36.0 Diabetic retinopathy
0.000 0.107 0.893
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.108 0.892
M06 Other rheumatoid arthritis
0.000 0.112 0.888
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.124 0.876
J33.8 Other polyp of sinus
0.000 0.144 0.856
E11.5 With peripheral circulatory complications
0.000 0.151 0.849
E10.6 With other specified complications
0.000 0.151 0.849
M05-M14 Inflammatory polyarthropathies
0.000 0.152 0.848
E11.6 With other specified complications
0.000 0.152 0.848
M05 Seropositive rheumatoid arthritis
0.000 0.158 0.842
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.161 0.839
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.166 0.834
E11.1 With ketoacidosis
0.000 0.168 0.832
E14.8 With unspecified complications
0.000 0.173 0.827
K90.9 Intestinal malabsorption, unspecified
0.000 0.173 0.827
E11.2 With renal complications
0.000 0.177 0.823
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.179 0.821
E14.6 With other specified complications
0.000 0.189 0.811
E11.3 With ophthalmic complications
0.000 0.191 0.809
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.202 0.797
J45 Asthma
0.000 0.213 0.787
E14.1 With ketoacidosis
0.000 0.218 0.782
M35 Other systemic involvement of connective tissue
0.000 0.230 0.770
M06.4 Inflammatory polyarthropathy
0.000 0.241 0.759
E06.3 Autoimmune thyroiditis
0.000 0.241 0.759
J33.1 Polypoid sinus degeneration
0.000 0.267 0.733
M20-M25 Other joint disorders
0.000 0.279 0.721
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.280 0.720
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E06.5 Other chronic thyroiditis
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.716
E14.0 With coma
0.000 0.283 0.716
J40-J47 Chronic lower respiratory diseases
0.000 0.291 0.709
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.291 0.709
E06.9 Thyroiditis, unspecified
0.000 0.291 0.709
E11.7 With multiple complications
0.000 0.292 0.708
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.295 0.705
E14.5 With peripheral circulatory complications
0.000 0.296 0.704
D50.9 Iron deficiency anaemia, unspecified
0.000 0.305 0.695
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.307 0.693
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.307 0.692
J44 Other chronic obstructive pulmonary disease
0.000 0.314 0.686
E20-E35 Disorders of other endocrine glands
0.000 0.314 0.686
M86-M90 Other osteopathies
0.000 0.315 0.685
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.317 0.683
D50 Iron deficiency anaemia
0.000 0.322 0.678
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.327 0.673
M86 Osteomyelitis
0.000 0.328 0.672
M05.8 Other seropositive rheumatoid arthritis
0.000 0.328 0.672
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.329 0.671
E13 Other specified diabetes mellitus
0.000 0.330 0.670
M86.9 Osteomyelitis, unspecified
0.000 0.335 0.665
E40-E46 Malnutrition
0.000 0.337 0.663
D50-D53 Nutritional anaemias
0.000 0.337 0.663
J43 Emphysema
0.000 0.338 0.662
D64.9 Anaemia, unspecified
0.000 0.340 0.660
M32 Systemic lupus erythematosus
0.000 0.341 0.659
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.345 0.655
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.347 0.652
E14.2 Withrenal complications
0.000 0.348 0.652
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.348 0.652
D64 Other anaemias
0.000 0.348 0.652
E06.1 Subacute thyroiditis
0.000 0.349 0.651
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.349 0.651
D60-D64 Aplastic and other anaemias
0.000 0.349 0.651
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.350 0.650
K90.3 Pancreatic steatorrhoea
0.000 0.352 0.647
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.352 0.647
K90.1 Tropical sprue
0.000 0.352 0.647
J43.9 Emphysema, unspecified
0.000 0.355 0.645
E06.4 Drug-induced thyroiditis
0.000 0.356 0.644
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.356 0.644
E06.0 Acute thyroiditis
0.000 0.356 0.644
K90.8 Other intestinal malabsorption
0.000 0.356 0.644
E11.8 With unspecified complications
0.000 0.357 0.643
# Top node
0.000 0.358 0.642
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.360 0.640
M06.2 Rheumatoid bursitis
0.000 0.363 0.637
E03.8 Other specified hypothyroidism
0.000 0.364 0.636
K90-K93 Other diseases of the digestive system
0.000 0.365 0.635
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.369 0.631
E11.4 With neurological complications
0.000 0.369 0.631
Chapter X Diseases of the respiratory system
0.000 0.370 0.630
E14.4 With neurological complications
0.000 0.373 0.627
M35.7 Hypermobility syndrome
0.000 0.373 0.627
M91-M94 Chondropathies
0.000 0.376 0.624
M12 Other specific arthropathies
0.000 0.382 0.618
D50.8 Other iron deficiency anaemias
0.000 0.384 0.616
J30-J39 Other diseases of upper respiratory tract
0.000 0.386 0.614
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.391 0.609
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.392 0.608
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.392 0.608
K86 Other diseases of pancreas
0.000 0.393 0.607
E23 Hypofunction and other disorders of pituitary gland
0.000 0.394 0.606
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.396 0.604
M05.1 Rheumatoid lung disease
0.000 0.396 0.604
M05.0 Felty's syndrome
0.000 0.396 0.604
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.398 0.602
M75 Shoulder lesions
0.000 0.400 0.600
M34 Systemic sclerosis
0.000 0.400 0.600
M14 Arthropathies in other diseases classified elsewhere
0.000 0.401 0.599
M70-M79 Other soft tissue disorders
0.000 0.403 0.597
M06.1 Adult-onset Still's disease
0.000 0.407 0.592
Chapter XI Diseases of the digestive system
0.000 0.408 0.592
K86.1 Other chronic pancreatitis
0.000 0.409 0.591
M75.3 Calcific tendinitis of shoulder
0.000 0.409 0.591
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.410 0.590
E05.8 Other thyrotoxicosis
0.000 0.410 0.590
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.411 0.589
K86.8 Other specified diseases of pancreas
0.000 0.411 0.589
M08 Juvenile arthritis
0.000 0.412 0.588
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.418 0.582
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.420 0.580
G35 Multiple sclerosis
0.580 0.420 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.423 0.576
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.427 0.573
M31 Other necrotising vasculopathies
0.000 0.434 0.566
E23.2 Diabetes insipidus
0.000 0.441 0.559
E50-E64 Other nutritional deficiencies
0.000 0.441 0.559
J45.0 Predominantly allergic asthma
0.000 0.442 0.558
M86.94 Osteomyelitis, unspecified (Hand)
0.000 0.443 0.557
M75.0 Adhesive capsulitis of shoulder
0.000 0.444 0.556
M75.9 Shoulder lesion, unspecified
0.000 0.444 0.556
M94 Other disorders of cartilage
0.000 0.444 0.556
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.448 0.552
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.448 0.552
M35.5 Multifocal fibrosclerosis
0.000 0.448 0.552
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.448 0.552
E28 Ovarian dysfunction
0.000 0.449 0.551
E24 Cushing's syndrome
0.000 0.450 0.550
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.450 0.550
E16.1 Other hypoglycaemia
0.000 0.452 0.548
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.454 0.546
M86.96 Osteomyelitis, unspecified (Lower leg)
0.000 0.454 0.546
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.455 0.545
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.455 0.545
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.455 0.545
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.455 0.545
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.455 0.545
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.455 0.545
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.455 0.545
M22 Disorders of patella
0.000 0.457 0.543
M06.8 Other specified rheumatoid arthritis
0.000 0.461 0.538
E07 Other disorders of thyroid
0.000 0.462 0.538
M90 Osteopathies in diseases classified elsewhere
0.000 0.463 0.536
M06.3 Rheumatoid nodule
0.000 0.468 0.532
M94.8 Other specified disorders of cartilage
0.000 0.470 0.530
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.473 0.527
M11 Other crystal arthropathies
0.000 0.474 0.526
M05.2 Rheumatoid vasculitis
0.000 0.475 0.525
M88 Paget's disease of bone [osteitis deformans]
0.000 0.476 0.524
M75.2 Bicipital tendinitis
0.000 0.476 0.524
M94.86 Other specified disorders of cartilage (Lower leg)
0.000 0.478 0.522
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.478 0.522
E11.0 With coma
0.000 0.478 0.521
E29 Testicular dysfunction
0.000 0.483 0.517
D53 Other nutritional anaemias
0.000 0.483 0.517
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
R80 Isolated proteinuria
0.000 0.487 0.513
J45.1 Nonallergic asthma
0.000 0.488 0.512
M10 Gout
0.000 0.488 0.512
D50.1 Sideropenic dysphagia
0.000 0.488 0.512
R40 Somnolence, stupor and coma
0.000 0.490 0.510
K83 Other diseases of biliary tract
0.000 0.491 0.509
R40.0 Somnolence
0.000 0.492 0.508
E28.3 Primary ovarian failure
0.000 0.493 0.507
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.000 0.493 0.507
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.493 0.506
M34.1 CR(E)ST syndrome
0.000 0.494 0.506
M35.0 Sicca syndrome [Sjogren]
0.000 0.495 0.505
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.000 0.496 0.504
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.000 0.497 0.503
M86.6 Other chronic osteomyelitis
0.000 0.497 0.502
M86.8 Other osteomyelitis
0.000 0.500 0.500
M93 Other osteochondropathies
0.000 0.501 0.499
M21 Other acquired deformities of limbs
0.000 0.501 0.499
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.000 0.501 0.499
J32 Chronic sinusitis
0.000 0.502 0.498
E23.7 Disorder of pituitary gland, unspecified
0.000 0.502 0.498
M12.3 Palindromic rheumatism
0.000 0.503 0.497
M75.4 Impingement syndrome of shoulder
0.000 0.505 0.495
M32.8 Other forms of systemic lupus erythematosus
0.000 0.505 0.494
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.508 0.492
E32 Diseases of thymus
0.000 0.508 0.492
E30 Disorders of puberty, not elsewhere classified
0.000 0.508 0.492
M30 Polyarteritis nodosa and related conditions
0.000 0.509 0.491
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.511 0.489
J41 Simple and mucopurulent chronic bronchitis
0.000 0.512 0.488
K83.0 Cholangitis
0.000 0.514 0.486
E27 Other disorders of adrenal gland
0.000 0.514 0.486
M14.6 Neuropathic arthropathy
0.000 0.515 0.485
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.516 0.484
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.000 0.517 0.483
E20 Hypoparathyroidism
0.000 0.518 0.482
M86.5 Other chronic haematogenous osteomyelitis
0.000 0.518 0.482
M86.3 Chronic multifocal osteomyelitis
0.000 0.518 0.482
M86.2 Subacute osteomyelitis
0.000 0.518 0.482
M86.0 Acute haematogenous osteomyelitis
0.000 0.518 0.482
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.518 0.482
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.518 0.482
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.518 0.482
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.518 0.482
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.518 0.482
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.518 0.482
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.518 0.482
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.518 0.482
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.518 0.482
E23.6 Other disorders of pituitary gland
0.000 0.518 0.482
E13.8 With unspecified complications
0.000 0.520 0.480
E13.7 With multiple complications
0.000 0.520 0.480
E13.6 With other specified complications
0.000 0.520 0.480
E13.5 With peripheral circulatory complications
0.000 0.520 0.480
E13.4 With neurological complications
0.000 0.520 0.480
E13.2 With renal complications
0.000 0.520 0.480
E13.1 With ketoacidosis
0.000 0.520 0.480
E13.0 With coma
0.000 0.520 0.480
R47-R49 Symptoms and signs involving speech and voice
0.000 0.521 0.479
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.523 0.477
R40.2 Coma, unspecified
0.000 0.523 0.477
M86.93 Osteomyelitis, unspecified (Forearm)
0.000 0.523 0.476
M86.92 Osteomyelitis, unspecified (Upper arm)
0.000 0.523 0.476
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.000 0.523 0.476
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.000 0.523 0.476
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.524 0.476
E45 Retarded development following protein-energy malnutrition
0.000 0.524 0.476
E43 Unspecified severe protein-energy malnutrition
0.000 0.524 0.476
E42 Marasmic kwashiorkor
0.000 0.524 0.476
E41 Nutritional marasmus
0.000 0.524 0.476
E40 Kwashiorkor
0.000 0.524 0.476
J43.1 Panlobular emphysema
0.000 0.525 0.475
J43.0 MacLeod's syndrome
0.000 0.525 0.475
M25 Other joint disorders, not elsewhere classified
0.000 0.527 0.473
E13.9 Without complications
0.000 0.527 0.473
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.527 0.472
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.527 0.472
E61 Deficiency of other nutrient elements
0.000 0.528 0.472
R49 Voice disturbances
0.000 0.528 0.472
M06.0 Seronegative rheumatoid arthritis
0.000 0.528 0.472
M35.1 Other overlap syndromes
0.000 0.528 0.471
M86.1 Other acute osteomyelitis
0.000 0.529 0.471
M90.7 Fracture of bone in neoplastic disease
0.000 0.530 0.470
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.532 0.467
D64.4 Congenital dyserythropoietic anaemia
0.000 0.532 0.468
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.532 0.468
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.532 0.468
R49.0 Dysphonia
0.000 0.533 0.467
M34.0 Progressive systemic sclerosis
0.000 0.533 0.467
M25.3 Other instability of joint
0.000 0.534 0.466
E27.1 Primary adrenocortical insufficiency
0.000 0.534 0.466
D80-D89 Certain disorders involving the immune mechanism
0.000 0.534 0.466
R44 Other symptoms and signs involving general sensations and perceptions
0.000 0.535 0.465
D61 Other aplastic anaemias
0.000 0.535 0.464
K86.3 Pseudocyst of pancreas
0.000 0.536 0.464
E26 Hyperaldosteronism
0.000 0.537 0.462
E25 Adrenogenital disorders
0.000 0.538 0.461
M12.5 Traumatic arthropathy
0.000 0.539 0.461
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.543 0.457
M06.28 Rheumatoid bursitis (Other)
0.000 0.543 0.457
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.543 0.457
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.543 0.457
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.543 0.457
M06.24 Rheumatoid bursitis (Hand)
0.000 0.543 0.457
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.543 0.457
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.543 0.457
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.543 0.457
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.543 0.457
D64.0 Hereditary sideroblastic anaemia
0.000 0.544 0.456
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.545 0.455
E31 Polyglandular dysfunction
0.000 0.545 0.455
J32.4 Chronic pansinusitis
0.000 0.546 0.454
M60-M63 Disorders of muscles
0.000 0.547 0.453
M21.4 Flat foot [pes planus] (acquired)
0.000 0.548 0.452
K86.9 Disease of pancreas, unspecified
0.000 0.548 0.452
M22.9 Disorder of patella, unspecified
0.000 0.549 0.451
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.551 0.449
H36 Retinal disorders in diseases classified elsewhere
0.000 0.553 0.447
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.000 0.553 0.447
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.554 0.446
M35.8 Other specified systemic involvement of connective tissue
0.000 0.554 0.445
M34.8 Other forms of systemic sclerosis
0.000 0.555 0.445
M22.0 Recurrent dislocation of patella
0.000 0.555 0.445
M25.31 Other instability of joint (Shoulder region)
0.000 0.556 0.444
M12.4 Intermittent hydrarthrosis
0.000 0.557 0.443
M12.1 Kaschin-Beck disease
0.000 0.557 0.443
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.557 0.443
J45.8 Mixed asthma
0.000 0.557 0.443
E13.3 With ophthalmic complications
0.000 0.558 0.442
J32.2 Chronic ethmoidal sinusitis
0.000 0.558 0.442
D53.9 Nutritional anaemia, unspecified
0.000 0.558 0.442
M31.7 Microscopic polyangiitis
0.000 0.560 0.440
R73 Elevated blood glucose level
0.000 0.561 0.439
R73.9 Hyperglycaemia, unspecified
0.000 0.561 0.439
M92 Other juvenile osteochondrosis
0.000 0.563 0.437
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.563 0.437
E54 Ascorbic acid deficiency
0.000 0.563 0.437
D51 Vitamin B12 deficiency anaemia
0.000 0.564 0.436
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.564 0.436
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.564 0.436
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.564 0.436
M09.0 Juvenile arthritis in psoriasis
0.000 0.564 0.436
M25.7 Osteophyte
0.000 0.564 0.436
D64.3 Other sideroblastic anaemias
0.000 0.564 0.436
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.565 0.435
E23.1 Drug-induced hypopituitarism
0.000 0.565 0.435
M86.4 Chronic osteomyelitis with draining sinus
0.000 0.565 0.434
M05.09 Felty's syndrome (Site unspecified)
0.000 0.567 0.433
M05.08 Felty's syndrome (Other)
0.000 0.567 0.433
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.567 0.433
M05.06 Felty's syndrome (Lower leg)
0.000 0.567 0.433
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.567 0.433
M05.04 Felty's syndrome (Hand)
0.000 0.567 0.433
M05.03 Felty's syndrome (Forearm)
0.000 0.567 0.433
M05.02 Felty's syndrome (Upper arm)
0.000 0.567 0.433
M05.01 Felty's syndrome (Shoulder region)
0.000 0.567 0.433
M05.00 Felty's syndrome (Multiple sites)
0.000 0.567 0.433
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.567 0.433
M05.18 Rheumatoid lung disease (Other)
0.000 0.567 0.433
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.567 0.433
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.567 0.433
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.567 0.433
M05.14 Rheumatoid lung disease (Hand)
0.000 0.567 0.433
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.567 0.433
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.567 0.433
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.567 0.433
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.567 0.433
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.567 0.433
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.567 0.433
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.567 0.433
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.567 0.433
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.567 0.433
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.567 0.433
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.567 0.433
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.567 0.433
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.567 0.433
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.567 0.433
R44.3 Hallucinations, unspecified
0.000 0.567 0.433
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.569 0.430
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)
0.000 0.569 0.431
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.570 0.429
M14.4 Arthropathy in amyloidosis
0.000 0.570 0.429
M14.3 Lipoid dermatoarthritis
0.000 0.570 0.429
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.570 0.429
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.570 0.429
M86.86 Other osteomyelitis (Lower leg)
0.000 0.571 0.429
E24.2 Drug-induced Cushing's syndrome
0.000 0.572 0.428
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.572 0.428
M25.36 Other instability of joint (Lower leg)
0.000 0.572 0.428
M88.9 Paget's disease of bone, unspecified
0.000 0.573 0.427
J43.2 Centrilobular emphysema
0.000 0.573 0.427
J30 Vasomotor and allergic rhinitis
0.000 0.574 0.426
D64.8 Other specified anaemias
0.000 0.575 0.425
M06.18 Adult-onset Still's disease (Other)
0.000 0.575 0.425
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.575 0.425
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.575 0.425
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.575 0.425
M06.14 Adult-onset Still's disease (Hand)
0.000 0.575 0.425
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.575 0.425
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.575 0.425
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.575 0.425
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.575 0.425
M25.76 Osteophyte (Lower leg)
0.000 0.575 0.425
K85 Acute pancreatitis
0.000 0.576 0.424
M31.6 Other giant cell arteritis
0.000 0.577 0.423
M22.2 Patellofemoral disorders
0.000 0.577 0.423
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.578 0.422
E46 Unspecified protein-energy malnutrition
0.000 0.578 0.422
M08.9 Juvenile arthritis, unspecified
0.000 0.578 0.422
M08.8 Other juvenile arthritis
0.000 0.578 0.422
M08.4 Pauciarticular juvenile arthritis
0.000 0.578 0.422
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.578 0.422
M08.2 Juvenile arthritis with systemic onset
0.000 0.578 0.422
M08.1 Juvenile ankylosing spondylitis
0.000 0.578 0.422
E24.9 Cushing's syndrome, unspecified
0.000 0.579 0.421
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.000 0.579 0.421
E61.1 Iron deficiency
0.000 0.580 0.420
D61.1 Drug-induced aplastic anaemia
0.000 0.581 0.419
M75.8 Other shoulder lesions
0.000 0.581 0.419
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.000 0.581 0.419
E22 Hyperfunction of pituitary gland
0.000 0.583 0.417
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.584 0.416
M00-M03 Infectious arthropathies
0.000 0.585 0.415
J42 Unspecified chronic bronchitis
0.000 0.585 0.415
M21.1 Varus deformity, not elsewhere classified
0.000 0.586 0.414
M93.9 Osteochondropathy, unspecified
0.000 0.590 0.410
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.590 0.409
M10.0 Idiopathic gout
0.000 0.592 0.408
R44.1 Visual hallucinations
0.000 0.592 0.408
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.593 0.407
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.594 0.406
M31.2 Lethal midline granuloma
0.000 0.594 0.406
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.000 0.595 0.405
M21.0 Valgus deformity, not elsewhere classified
0.000 0.595 0.404
D52 Folate deficiency anaemia
0.000 0.596 0.404
M25.77 Osteophyte (Ankle and foot)
0.000 0.596 0.404
M08.0 Juvenile rheumatoid arthritis
0.000 0.598 0.402
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.598 0.401
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.599 0.401
E50 Vitamin A deficiency
0.000 0.599 0.401
E60 Dietary zinc deficiency
0.000 0.599 0.401
E59 Dietary selenium deficiency
0.000 0.599 0.401
E52 Niacin deficiency [pellagra]
0.000 0.599 0.401
E24.0 Pituitary-dependent Cushing's disease
0.000 0.600 0.400
M94.3 Chondrolysis
0.000 0.601 0.399
M94.1 Relapsing polychondritis
0.000 0.601 0.399
E51 Thiamine deficiency
0.000 0.602 0.398
E29.1 Testicular hypofunction
0.000 0.603 0.397
M14.2 Diabetic arthropathy
0.000 0.604 0.396
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.604 0.396
E28.9 Ovarian dysfunction, unspecified
0.000 0.605 0.395
E28.8 Other ovarian dysfunction
0.000 0.605 0.395
E28.1 Androgen excess
0.000 0.605 0.395
E28.0 Oestrogen excess
0.000 0.605 0.395
E63 Other nutritional deficiencies
0.000 0.605 0.395
E24.8 Other Cushing's syndrome
0.000 0.606 0.394
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.606 0.394
E24.3 Ectopic ACTH syndrome
0.000 0.606 0.394
E24.1 Nelson's syndrome
0.000 0.606 0.394
M94.0 Chondrocostal junction syndrome [Tietze]
0.000 0.606 0.394
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.607 0.393
M31.8 Other specified necrotising vasculopathies
0.000 0.607 0.392
K83.4 Spasm of sphincter of Oddi
0.000 0.608 0.392
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.000 0.608 0.392
M36.3 Arthropathy in other blood disorders
0.000 0.608 0.392
M36.2 Haemophilic arthropathy
0.000 0.608 0.392
M36.1 Arthropathy in neoplastic disease
0.000 0.608 0.392
M36.0 Dermato(poly)myositis in neoplastic disease
0.000 0.608 0.392
M90.78 Fracture of bone in neoplastic disease (Other)
0.000 0.609 0.391

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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