TreeWAS – Variant ID: rs1570271

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D45 Polycythaemia vera	0.000	0.976	0.024
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.978	0.022
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.978	0.022
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.980	0.020
D43.2 Brain, unspecified	0.000	0.980	0.020
D43.0 Brain, supratentorial	0.000	0.982	0.018
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.982	0.018
D44.1 Adrenal gland	0.000	0.982	0.018
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.982	0.018
D46 Myelodysplastic syndromes	0.000	0.983	0.017
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.983	0.017
D43.4 Spinal cord	0.000	0.983	0.017
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.983	0.017
C54.1 Endometrium	0.016	0.984	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.984	0.016
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.984	0.016
D43.9 Central nervous system, unspecified	0.000	0.984	0.016
D43.7 Other parts of central nervous system	0.000	0.984	0.016
D43.3 Cranial nerves	0.000	0.984	0.016
D44.9 Endocrine gland, unspecified	0.000	0.984	0.016
D44.4 Craniopharyngeal duct	0.000	0.984	0.016
D43.1 Brain, infratentorial	0.000	0.984	0.015
D44.3 Pituitary gland	0.000	0.984	0.015
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.985	0.015
D38.1 Trachea, bronchus and lung	0.000	0.985	0.015
D44.7 Aortic body and other paraganglia	0.000	0.985	0.015
D40.0 Prostate	0.000	0.985	0.015
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.985	0.015
D44.5 Pineal gland	0.000	0.985	0.015
D44.2 Parathyroid gland	0.000	0.985	0.015
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.985	0.015
D44.0 Thyroid gland	0.000	0.985	0.014
D44.6 Carotid body	0.000	0.986	0.014
D37.6 Liver, gallbladder and bile ducts	0.000	0.986	0.014
D44.8 Pluriglandular involvement	0.000	0.986	0.014
D40.7 Other male genital organs	0.000	0.987	0.013
D37.2 Small intestine	0.000	0.987	0.013
D37.0 Lip, oral cavity and pharynx	0.000	0.987	0.013
D39.1 Ovary	0.000	0.987	0.013
D41.2 Ureter	0.000	0.987	0.013
D39.7 Other female genital organs	0.000	0.987	0.013
D40.9 Male genital organ, unspecified	0.000	0.987	0.013
D38.6 Respiratory organ, unspecified	0.000	0.987	0.013
D38.4 Thymus	0.000	0.987	0.013
D46.2 Refractory anaemia with excess of blasts	0.000	0.987	0.013
D46.4 Refractory anaemia, unspecified	0.000	0.987	0.013
D38.5 Other respiratory organs	0.000	0.987	0.013
D38.2 Pleura	0.000	0.987	0.013
D41.0 Kidney	0.000	0.987	0.013
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.987	0.013
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.987	0.013
D38.3 Mediastinum	0.000	0.987	0.012
D41.9 Urinary organ, unspecified	0.000	0.987	0.012
D41.7 Other urinary organs	0.000	0.987	0.012
D41.4 Bladder	0.000	0.987	0.013
D41.3 Urethra	0.000	0.987	0.012
D38.0 Larynx	0.000	0.987	0.012
D39.9 Female genital organ, unspecified	0.000	0.987	0.012
D39.2 Placenta	0.000	0.987	0.012
D41.1 Renal pelvis	0.000	0.988	0.012
D48.0 Bone and articular cartilage	0.000	0.988	0.012
D48.1 Connective and other soft tissue	0.000	0.988	0.012
D48.7 Other specified sites	0.000	0.988	0.012
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.988	0.012
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.988	0.012
D37.9 Digestive organ, unspecified	0.000	0.988	0.012
C54 Malignant neoplasm of corpus uteri	0.012	0.988	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.988	0.012
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.988	0.012
D42.1 Spinal meninges	0.000	0.988	0.012
D42.0 Cerebral meninges	0.000	0.988	0.012
D46.1 Refractory anaemia with sideroblasts	0.000	0.988	0.012
D39.0 Uterus	0.000	0.988	0.012
D46.7 Other myelodysplastic syndromes	0.000	0.988	0.011
D40.1 Testis	0.000	0.988	0.011
D42.9 Meninges, unspecified	0.000	0.988	0.011
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.989	0.011
D47.4 Osteomyelofibrosis	0.000	0.989	0.011
D48.3 Retroperitoneum	0.000	0.989	0.011
D37.3 Appendix	0.000	0.989	0.011
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.989	0.011
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.011	0.989	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.989	0.010
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.989	0.010
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.990	0.010
D37.1 Stomach	0.000	0.990	0.010
C54.9 Corpus uteri, unspecified	0.010	0.990	0.000
D37.4 Colon	0.000	0.990	0.010
D48.4 Peritoneum	0.000	0.990	0.010
C18.7 Sigmoid colon	0.010	0.990	0.000
C18.5 Splenic flexure	0.009	0.990	0.000
C18 Malignant neoplasm of colon	0.009	0.991	0.000
C18.0 Caecum	0.009	0.991	0.000
D37.7 Other digestive organs	0.000	0.991	0.009
D47.1 Chronic myeloproliferative disease	0.000	0.991	0.009
D48.5 Skin	0.000	0.991	0.009
C54.8 Overlapping lesion of corpus uteri	0.009	0.991	0.000
C54.3 Fundus uteri	0.009	0.991	0.000
C54.2 Myometrium	0.009	0.991	0.000
C54.0 Isthmus uteri	0.009	0.991	0.000
D48.6 Breast	0.000	0.991	0.009
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.991	0.009
K56.6 Other and unspecified intestinal obstruction	0.009	0.991	0.000
K56.4 Other impaction of intestine	0.008	0.992	0.000
C18.2 Ascending colon	0.008	0.992	0.000
C18.9 Colon, unspecified	0.008	0.992	0.000
D37.5 Rectum	0.000	0.992	0.008
D47.2 Monoclonal gammopathy	0.000	0.992	0.007
K56 Paralytic ileus and intestinal obstruction without hernia	0.007	0.993	0.000
C18.8 Overlapping lesion of colon	0.007	0.993	0.000
C50.5 Lower-outer quadrant of breast	0.000	0.993	0.007
K56.0 Paralytic ileus	0.007	0.993	0.000
C18.3 Hepatic flexure	0.007	0.993	0.000
C51-C58 Malignant neoplasms of female genital organs	0.007	0.993	0.000
C18.4 Transverse colon	0.006	0.994	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.994	0.006
H11.9 Disorder of conjunctiva, unspecified	0.000	0.994	0.006
C52 Malignant neoplasm of vagina	0.006	0.994	0.000
K56.1 Intussusception	0.006	0.994	0.000
C56 Malignant neoplasm of ovary	0.006	0.994	0.000
K56.3 Gallstone ileus	0.006	0.994	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.006	0.994	0.000
C51 Malignant neoplasm of vulva	0.005	0.995	0.000
M23.49 Loose body in knee-Unspec lig/men	0.000	0.995	0.005
C58 Malignant neoplasm of placenta	0.005	0.995	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.005	0.995	0.000
H11 Other disorders of conjunctiva	0.000	0.995	0.005
K56.2 Volvulus	0.005	0.995	0.000
C20 Malignant neoplasm of rectum	0.005	0.995	0.000
C18.6 Descending colon	0.005	0.995	0.000
C18.1 Appendix	0.005	0.995	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.005	0.995	0.000
H65.3 Chronic mucoid otitis media	0.005	0.995	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.995	0.005
H11.8 Other specified disorders of conjunctiva	0.000	0.995	0.005
G47.9 Sleep disorder, unspecified	0.004	0.996	0.000
C15-C26 Malignant neoplasms of digestive organs	0.004	0.996	0.000
H11.3 Conjunctival haemorrhage	0.000	0.996	0.004
C51.0 Labium majus	0.004	0.996	0.000
C51.1 Labium minus	0.004	0.996	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.996	0.004
C51.8 Overlapping lesion of vulva	0.004	0.996	0.000
C51.2 Clitoris	0.004	0.996	0.000
C53 Malignant neoplasm of cervix uteri	0.004	0.996	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.004	0.996	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.996	0.004
C57.9 Female genital organ, unspecified	0.004	0.996	0.000
C57.7 Other specified female genital organs	0.004	0.996	0.000
C57.4 Uterine adnexa, unspecified	0.004	0.996	0.000
C57.3 Parametrium	0.004	0.996	0.000
C57.2 Round ligament	0.004	0.996	0.000
C57.1 Broad ligament	0.004	0.996	0.000
C22.0 Liver cell carcinoma	0.004	0.996	0.000
C57.8 Overlapping lesion of female genital organs	0.004	0.996	0.000
C57.0 Fallopian tube	0.004	0.996	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.004	0.996	0.000
C51.9 Vulva, unspecified	0.004	0.996	0.000
H11.2 Conjunctival scars	0.000	0.996	0.004
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.004	0.996	0.000
S02.4 Fracture of malar and maxillary bones	0.000	0.996	0.004
H11.0 Pterygium	0.000	0.996	0.004
C21 Malignant neoplasm of anus and anal canal	0.004	0.996	0.000
R73.0 Abnormal glucose tolerance test	0.000	0.996	0.004
I99 Other and unspecified disorders of circulatory system	0.000	0.996	0.004
H65 Nonsuppurative otitis media	0.004	0.996	0.000
H11.1 Conjunctival degenerations and deposits	0.000	0.996	0.003
C24.1 Ampulla of Vater	0.003	0.997	0.000
N80.3 Endometriosis of pelvic peritoneum	0.003	0.997	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.997	0.003
C26.0 Intestinal tract, part unspecified	0.003	0.997	0.000
C24.9 Biliary tract, unspecified	0.003	0.997	0.000
K56.7 Ileus, unspecified	0.003	0.997	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.997	0.003
C21.8 Overlapping lesion of rectum, anus and anal canal	0.003	0.997	0.000
C22.1 Intrahepatic bile duct carcinoma	0.003	0.997	0.000
C53.8 Overlapping lesion of cervix uteri	0.003	0.997	0.000
C53.1 Exocervix	0.003	0.997	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.997	0.003
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.000	0.997	0.003
C22.7 Other specified carcinomas of liver	0.003	0.997	0.000
C22.4 Other sarcomas of liver	0.003	0.997	0.000
C22.3 Angiosarcoma of liver	0.003	0.997	0.000
C22.2 Hepatoblastoma	0.003	0.997	0.000
C26.9 Ill-defined sites within the digestive system	0.003	0.997	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.003	0.997	0.000
H65.1 Other acute nonsuppurative otitis media	0.003	0.997	0.000
C21.0 Anus, unspecified	0.003	0.997	0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.000	0.997	0.003
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.997	0.003
C24.8 Overlapping lesion of biliary tract	0.003	0.997	0.000
C26.8 Overlapping lesion of digestive system	0.003	0.997	0.000
C26.1 Spleen	0.003	0.997	0.000
H65.4 Other chronic nonsuppurative otitis media	0.003	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.997	0.003
S06.5 Traumatic subdural haemorrhage	0.000	0.997	0.003
H65.9 Nonsuppurative otitis media, unspecified	0.003	0.997	0.000
H66.3 Other chronic suppurative otitis media	0.003	0.997	0.000
C23 Malignant neoplasm of gallbladder	0.003	0.997	0.000
H65.2 Chronic serous otitis media	0.003	0.997	0.000
C17 Malignant neoplasm of small intestine	0.003	0.997	0.000
C21.2 Cloacogenic zone	0.003	0.997	0.000
T39.1 4-Aminophenol derivatives	0.000	0.997	0.003
C22.9 Liver, unspecified	0.003	0.997	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.003	0.997	0.000
C53.9 Cervix uteri, unspecified	0.003	0.997	0.000
C17.0 Duodenum	0.003	0.997	0.000
C53.0 Endocervix	0.002	0.997	0.000
C21.1 Anal canal	0.003	0.997	0.000
H65.0 Acute serous otitis media	0.003	0.997	0.000
N80.1 Endometriosis of ovary	0.003	0.997	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
Q24.8 Other specified congenital malformations of heart	0.003	0.997	0.000
J98.1 Pulmonary collapse	0.003	0.997	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.997	0.003
C24.0 Extrahepatic bile duct	0.002	0.997	0.000
C25 Malignant neoplasm of pancreas	0.002	0.997	0.000
J35.0 Chronic tonsillitis	0.000	0.997	0.003
H66 Suppurative and unspecified otitis media	0.002	0.997	0.000
H65-H75 Diseases of middle ear and mastoid	0.002	0.998	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.998	0.002
T39.4 Antirheumatics, not elsewhere classified	0.000	0.998	0.002
T39.2 Pyrazolone derivatives	0.000	0.998	0.002
Q24 Other congenital malformations of heart	0.002	0.998	0.000
C25.9 Pancreas, unspecified	0.002	0.998	0.000
C17.8 Overlapping lesion of small intestine	0.002	0.998	0.000
C17.3 Meckel's diverticulum	0.002	0.998	0.000
C17.1 Jejunum	0.002	0.998	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.002	0.998	0.000
R61.9 Hyperhidrosis, unspecified	0.002	0.998	0.000
T39.0 Salicylates	0.000	0.998	0.002
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.998	0.002
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.998	0.002
H66.0 Acute suppurative otitis media	0.002	0.998	0.000
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
H69 Other disorders of Eustachian tube	0.002	0.998	0.000
H73 Other disorders of tympanic membrane	0.002	0.998	0.000
C25.8 Overlapping lesion of pancreas	0.002	0.998	0.000
C25.7 Other parts of pancreas	0.002	0.998	0.000
H74 Other disorders of middle ear and mastoid	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
C25.3 Pancreatic duct	0.002	0.998	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.002	0.998	0.000
H70 Mastoiditis and related conditions	0.002	0.998	0.000
J81 Pulmonary oedema	0.002	0.998	0.000
M23.4 Loose body in knee	0.000	0.998	0.002
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.998	0.002
Q24.6 Congenital heart block	0.002	0.998	0.000
C25.1 Body of pancreas	0.002	0.998	0.000
Q24.0 Dextrocardia	0.002	0.998	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.998	0.000
Q24.2 Cor triatriatum	0.002	0.998	0.000
Q24.1 Levocardia	0.002	0.998	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H67 Otitis media in diseases classified elsewhere	0.002	0.998	0.000
G62.9 Polyneuropathy, unspecified	0.002	0.998	0.000
H66.4 Suppurative otitis media, unspecified	0.002	0.998	0.000
J36 Peritonsillar abscess	0.000	0.998	0.002
H74.9 Disorder of middle ear and mastoid, unspecified	0.002	0.998	0.000
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
H68 Eustachian salpingitis and obstruction	0.002	0.998	0.000
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.998	0.002
C17.2 Ileum	0.001	0.998	0.001
C25.4 Endocrine pancreas	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.000	0.998	0.002
C16 Malignant neoplasm of stomach	0.002	0.998	0.000
C17.9 Small intestine, unspecified	0.001	0.998	0.001
G47.8 Other sleep disorders	0.002	0.998	0.000
H06.2 Dysthyroid exophthalmos	0.002	0.998	0.000
G47 Sleep disorders	0.002	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
H73.1 Chronic myringitis	0.002	0.998	0.000
H74.1 Adhesive middle ear disease	0.002	0.998	0.000
Q27 Other congenital malformations of peripheral vascular system	0.002	0.998	0.000
H70.1 Chronic mastoiditis	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.998	0.002
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.998	0.002
H66.2 Chronic atticoantral suppurative otitis media	0.002	0.998	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.998	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
D11.0 Parotid gland	0.000	0.998	0.002
H69.0 Patulous Eustachian tube	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.998	0.002
H74.0 Tympanosclerosis	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
G47.1 Disorders of excessive somnolence [hypersomnias]	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.000	0.998	0.002
H74.3 Other acquired abnormalities of ear ossicles	0.002	0.998	0.000
Q25.3 Stenosis of aorta	0.002	0.998	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
H73.0 Acute myringitis	0.002	0.998	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
T50.8 Diagnostic agents	0.000	0.998	0.002
M23.40 Loose body in knee-Mult sites	0.000	0.998	0.002
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.002	0.998	0.000
M23.47 Loose body in knee-Capsular lig	0.000	0.998	0.002
M23.45 Loose body in knee-Pst hrn lat men	0.000	0.998	0.002
C25.2 Tail of pancreas	0.001	0.998	0.000
H70.2 Petrositis	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
M23.44 Loose body in knee-Lat lig/ant men	0.000	0.998	0.002
H70.8 Other mastoiditis and related conditions	0.002	0.998	0.000
Q25.1 Coarctation of aorta	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
Q26 Congenital malformations of great veins	0.002	0.998	0.000
M23.46 Loose body in knee-O/unsp lat men	0.000	0.998	0.002
H70.0 Acute mastoiditis	0.002	0.998	0.000
Q25.0 Patent ductus arteriosus	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.000	0.998	0.002
T50.4 Drugs affecting uric acid metabolism	0.000	0.998	0.002
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
S06 Intracranial injury	0.000	0.998	0.002
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.998	0.002
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
C16.1 Fundus of stomach	0.002	0.998	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.002	0.998	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.002	0.998	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.002	0.998	0.000
H74.4 Polyp of middle ear	0.002	0.998	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.000	0.998	0.002
H71 Cholesteatoma of middle ear	0.002	0.998	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.998	0.002
C16.8 Overlapping lesion of stomach	0.002	0.998	0.000
H70.9 Mastoiditis, unspecified	0.002	0.998	0.000
Q25.4 Other congenital malformations of aorta	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
H68.0 Eustachian salpingitis	0.001	0.998	0.000
N80.2 Endometriosis of Fallopian tube	0.002	0.998	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.002	0.998	0.000
Q25.8 Other congenital malformations of great arteries	0.002	0.998	0.000
Q25.5 Atresia of pulmonary artery	0.002	0.998	0.000
Q25.2 Atresia of aorta	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.998	0.002
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.000	0.998	0.002
Q25.6 Stenosis of pulmonary artery	0.002	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.998	0.002
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.998	0.002
C16.3 Pyloric antrum	0.002	0.998	0.000
D11.9 Major salivary gland, unspecified	0.000	0.998	0.002
D11.7 Other major salivary glands	0.000	0.998	0.002
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.998	0.000
T42.0 Hydantoin derivatives	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
H54.0 Blindness, both eyes	0.002	0.998	0.000
H69.8 Other specified disorders of Eustachian tube	0.001	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.000	0.998	0.002
T42.4 Benzodiazepines	0.000	0.998	0.002
T81.3 Disruption of operation wound, not elsewhere classified	0.000	0.998	0.002
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.998	0.002
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.998	0.002
H68.1 Obstruction of Eustachian tube	0.001	0.998	0.000
Q27.4 Congenital phlebectasia	0.001	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.001	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.001	0.998	0.000
C16.2 Body of stomach	0.001	0.998	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.001	0.998	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.002	0.998	0.000
T40.4 Other synthetic narcotics	0.000	0.998	0.002
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.001
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.002
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
M23.43 Loose body in knee-Med lig/oth men	0.000	0.998	0.001
Q23.0 Congenital stenosis of aortic valve	0.001	0.998	0.000
S06.8 Other intracranial injuries	0.000	0.998	0.002
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.998	0.002
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.001
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.001
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.001
T50.5 Appetite depressants	0.000	0.998	0.001
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.001
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.001
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.998	0.002
C16.5 Lesser curvature of stomach, unspecified	0.001	0.998	0.000
I49.0 Ventricular fibrillation and flutter	0.002	0.998	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.002	0.998	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.001	0.998	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.001	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.001	0.998	0.000
S06.1 Traumatic cerebral oedema	0.000	0.998	0.001
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.001
T46.7 Peripheral vasodilators	0.000	0.998	0.001
N80 Endometriosis	0.002	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.001	0.998	0.000
C16.6 Greater curvature of stomach, unspecified	0.001	0.998	0.000
I31.9 Disease of pericardium, unspecified	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.001
N85.2 Hypertrophy of uterus	0.002	0.998	0.000
S06.9 Intracranial injury, unspecified	0.000	0.998	0.001
G47.4 Narcolepsy and cataplexy	0.001	0.998	0.000
G47.2 Disorders of the sleep-wake schedule	0.001	0.998	0.000
K02.9 Dental caries, unspecified	0.000	0.998	0.002
N88.8 Other specified noninflammatory disorders of cervix uteri	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.001	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.001
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.001
H54.1 Blindness, one eye, low vision, other eye	0.001	0.998	0.000
Q21.4 Aortopulmonary septal defect	0.001	0.998	0.000
Q21.2 Atrioventricular septal defect	0.001	0.998	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.001	0.998	0.000
Q26.8 Other congenital malformations of great veins	0.001	0.998	0.000
Q26.6 Portal vein-hepatic artery fistula	0.001	0.998	0.000
Q26.5 Anomalous portal venous connexion	0.001	0.998	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.001	0.998	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.001	0.998	0.000
Q26.1 Persistent left superior vena cava	0.001	0.998	0.000
Q26.0 Congenital stenosis of vena cava	0.001	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.000	0.998	0.001
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.001
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.001
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.998	0.002
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.001
H10-H13 Disorders of conjunctiva	0.000	0.998	0.002
S02.30 Fracture of orbital floor (closed)	0.000	0.998	0.001
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.998	0.001
C16.4 Pylorus	0.001	0.998	0.000
G43.1 Migraine with aura [classical migraine]	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.001
D11 Benign neoplasm of major salivary glands	0.000	0.998	0.002
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.998	0.001
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.998	0.001
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.998	0.001
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.001	0.998	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.001	0.998	0.000
Q20.6 Isomerism of atrial appendages	0.001	0.998	0.000
Q20.5 Discordant atrioventricular connexion	0.001	0.998	0.000
Q20.4 Double inlet ventricle	0.001	0.998	0.000
Q20.3 Discordant ventriculoarterial connexion	0.001	0.998	0.000
Q20.2 Double outlet left ventricle	0.001	0.998	0.000
Q20.1 Double outlet right ventricle	0.001	0.998	0.000
Q20.0 Common arterial trunk	0.001	0.998	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.001	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.001	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.001	0.998	0.000
Q23.2 Congenital mitral stenosis	0.001	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.001	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.001	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.001	0.998	0.000
T42.3 Barbiturates	0.000	0.998	0.001
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.001
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.001
Z86.1 Personal history of infectious and parasitic diseases	0.002	0.998	0.000
Z90.7 Acquired absence of genital organ(s)	0.002	0.998	0.000
H54 Blindness and low vision	0.002	0.998	0.000
J84 Other interstitial pulmonary diseases	0.001	0.998	0.000
M89.98 Disorder of bone, unspecified (Other)	0.000	0.998	0.001
S42.10 Fracture of scapula (closed)	0.001	0.998	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.999	0.001
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.999	0.001
D07.5 Prostate	0.001	0.999	0.000
Q28.3 Other malformations of cerebral vessels	0.001	0.999	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.999	0.001
T38.7 Androgens and anabolic congeners	0.000	0.999	0.001
T38.4 Oral contraceptives	0.000	0.999	0.001
T38.2 Antithyroid drugs	0.000	0.999	0.001
T38.1 Thyroid hormones and substitutes	0.000	0.999	0.001
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.999	0.001
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.999	0.001
D33.3 Cranial nerves	0.000	0.999	0.001
M80.9 Unspecified osteoporosis with pathological fracture	0.001	0.999	0.000
Q21.1 Atrial septal defect	0.001	0.999	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.999	0.001
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.999	0.001
T42.2 Succinimides and oxazolidinediones	0.000	0.999	0.001
T43.6 Psychostimulants with abuse potential	0.000	0.999	0.001
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
Q23.3 Congenital mitral insufficiency	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations