TreeWAS – Variant ID: rs1633266

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I12.0 Hypertensive renal disease with renal failure	0.000	0.914	0.086
I12 Hypertensive renal disease	0.000	0.958	0.042
I12.9 Hypertensive renal disease without renal failure	0.000	0.972	0.028
I51.8 Other ill-defined heart diseases	0.000	0.984	0.016
H74 Other disorders of middle ear and mastoid	0.014	0.986	0.000
I10-I15 Hypertensive diseases	0.000	0.987	0.013
H74.4 Polyp of middle ear	0.013	0.987	0.000
H65-H75 Diseases of middle ear and mastoid	0.013	0.987	0.000
I11 Hypertensive heart disease	0.000	0.988	0.012
H65 Nonsuppurative otitis media	0.012	0.988	0.000
H73 Other disorders of tympanic membrane	0.012	0.988	0.000
H73.8 Other specified disorders of tympanic membrane	0.011	0.989	0.000
H74.0 Tympanosclerosis	0.011	0.989	0.000
H69 Other disorders of Eustachian tube	0.011	0.989	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.011	0.989	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.011	0.989	0.000
I13 Hypertensive heart and renal disease	0.000	0.989	0.011
H70 Mastoiditis and related conditions	0.011	0.989	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.010	0.990	0.000
H74.1 Adhesive middle ear disease	0.010	0.990	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.990	0.010
H74.8 Other specified disorders of middle ear and mastoid	0.010	0.990	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.990	0.010
H65.9 Nonsuppurative otitis media, unspecified	0.010	0.990	0.000
H69.9 Eustachian tube disorder, unspecified	0.010	0.990	0.000
H65.2 Chronic serous otitis media	0.010	0.990	0.000
H66 Suppurative and unspecified otitis media	0.010	0.990	0.000
H65.0 Acute serous otitis media	0.010	0.990	0.000
H65.4 Other chronic nonsuppurative otitis media	0.010	0.990	0.000
H72 Perforation of tympanic membrane	0.009	0.991	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.009	0.991	0.000
H67 Otitis media in diseases classified elsewhere	0.009	0.991	0.000
H69.8 Other specified disorders of Eustachian tube	0.009	0.991	0.000
H70.9 Mastoiditis, unspecified	0.009	0.991	0.000
H68 Eustachian salpingitis and obstruction	0.009	0.991	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.991	0.009
H66.9 Otitis media, unspecified	0.009	0.991	0.000
H70.8 Other mastoiditis and related conditions	0.009	0.991	0.000
N19 Unspecified renal failure	0.000	0.991	0.009
H65.1 Other acute nonsuppurative otitis media	0.008	0.991	0.000
H73.1 Chronic myringitis	0.008	0.992	0.000
H72.8 Other perforations of tympanic membrane	0.008	0.992	0.000
H69.0 Patulous Eustachian tube	0.008	0.992	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.992	0.008
N42.8 Other specified disorders of prostate	0.008	0.992	0.000
H73.0 Acute myringitis	0.008	0.992	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.992	0.008
H73.9 Disorder of tympanic membrane, unspecified	0.008	0.992	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.992	0.008
H70.0 Acute mastoiditis	0.008	0.992	0.000
H70.2 Petrositis	0.008	0.992	0.000
H66.0 Acute suppurative otitis media	0.008	0.992	0.000
N13.4 Hydroureter	0.000	0.992	0.008
H72.2 Other marginal perforations of tympanic membrane	0.007	0.993	0.000
I15 Secondary hypertension	0.000	0.993	0.007
H70.1 Chronic mastoiditis	0.007	0.993	0.000
I44.0 Atrioventricular block, first degree	0.000	0.993	0.007
H66.4 Suppurative otitis media, unspecified	0.007	0.993	0.000
D13.1 Stomach	0.000	0.993	0.007
N13 Obstructive and reflux uropathy	0.000	0.993	0.007
M81.98 Osteoporosis, unspecified (Other)	0.000	0.993	0.007
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.993	0.007
H66.2 Chronic atticoantral suppurative otitis media	0.007	0.993	0.000
M81.9 Osteoporosis, unspecified	0.000	0.993	0.007
H67.8 Otitis media in other diseases classified elsewhere	0.007	0.993	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.007	0.993	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.007	0.993	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.007	0.993	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.007	0.993	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.993	0.007
H72.0 Central perforation of tympanic membrane	0.007	0.993	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.993	0.007
E04.9 Non-toxic goitre, unspecified	0.000	0.993	0.007
H66.1 Chronic tubotympanic suppurative otitis media	0.007	0.993	0.000
N13.8 Other obstructive and reflux uropathy	0.000	0.993	0.007
H68.0 Eustachian salpingitis	0.006	0.993	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.993	0.007
N42 Other disorders of prostate	0.007	0.993	0.000
H68.1 Obstruction of Eustachian tube	0.006	0.994	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.994	0.006
H72.1 Attic perforation of tympanic membrane	0.006	0.994	0.000
N92.6 Irregular menstruation, unspecified	0.006	0.994	0.000
N42.9 Disorder of prostate, unspecified	0.006	0.994	0.000
N42.2 Atrophy of prostate	0.006	0.994	0.000
H66.3 Other chronic suppurative otitis media	0.006	0.994	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.994	0.006
N13.3 Other and unspecified hydronephrosis	0.000	0.994	0.006
I15.9 Seconday hypertension, unspecified	0.000	0.994	0.005
H65.3 Chronic mucoid otitis media	0.006	0.994	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.994	0.005
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.994	0.005
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.995	0.005
N42.1 Congestion and haemorrhage of prostate	0.005	0.995	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.995	0.005
I15.0 Renovascular hypertension	0.000	0.995	0.005
I15.8 Other secondary hypertension	0.000	0.995	0.005
I15.2 Hypertension secondary to endocrine disorders	0.000	0.995	0.005
I34 Nonrheumatic mitral valve disorders	0.000	0.995	0.005
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.995	0.005
N42.3 Dysplasia of prostate	0.005	0.995	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.995	0.005
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.995	0.005
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.995	0.005
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.995	0.005
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.995	0.005
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.995	0.005
I15.1 Hypertension secondary to other renal disorders	0.000	0.995	0.004
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.995	0.004
H72.9 Perforation of tympanic membrane, unspecified	0.004	0.995	0.000
N13.6 Pyonephrosis	0.000	0.995	0.004
N18.0 End-stage renal disease	0.000	0.996	0.004
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.000	0.996	0.004
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.996	0.004
E10.3 With ophthalmic complications	0.000	0.996	0.004
N42.0 Calculus of prostate	0.004	0.996	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.996	0.004
K70.3 Alcoholic cirrhosis of liver	0.000	0.996	0.004
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.996	0.004
N18 Chronic renal failure	0.000	0.996	0.004
N17-N19 Renal failure	0.000	0.996	0.004
N05.9 Unspecified	0.000	0.997	0.003
E87.0 Hyperosmolality and hypernatraemia	0.003	0.997	0.000
Z98.1 Arthrodesis status	0.003	0.997	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.997	0.003
N18.5 Chronic kidney disease, stage 5	0.000	0.997	0.003
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.997	0.003
N18.9 Chronic renal failure, unspecified	0.000	0.997	0.003
R49.0 Dysphonia	0.000	0.997	0.003
K70 Alcoholic liver disease	0.000	0.997	0.003
M81 Osteoporosis without pathological fracture	0.000	0.997	0.003
N18.2 Chronic kidney disease, stage 2	0.000	0.997	0.003
N18.1 Chronic kidney disease, stage 1	0.000	0.997	0.003
E10.4 With neurological complications	0.000	0.997	0.003
Chapter VIII Diseases of the ear and mastoid process	0.003	0.997	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.997	0.003
N18.8 Other chronic renal failure	0.000	0.997	0.003
K70.9 Alcoholic liver disease, unspecified	0.000	0.997	0.003
I51 Complications and ill-defined descriptions of heart disease	0.000	0.997	0.003
I34.1 Mitral (valve) prolapse	0.000	0.997	0.003
N05.8 Other	0.000	0.997	0.003
Z45.0 Adjustment and management of cardiac pacemaker	0.000	0.997	0.003
K70.0 Alcoholic fatty liver	0.000	0.997	0.003
M11.26 Other chondrocalcinosis (Lower leg)	0.003	0.997	0.000
H61.2 Impacted cerumen	0.003	0.997	0.000
M89.8 Other specified disorders of bone	0.000	0.997	0.003
N05 Unspecified nephritic syndrome	0.000	0.997	0.003
E10 Insulin-dependent diabetes mellitus	0.000	0.997	0.003
H71 Cholesteatoma of middle ear	0.002	0.997	0.001
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
I44 Atrioventricular and left bundle-branch block	0.000	0.997	0.003
I69.3 Sequelae of cerebral infarction	0.003	0.997	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.997	0.003
K70.4 Alcoholic hepatic failure	0.000	0.997	0.003
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.997	0.002
R41.3 Other amnesia	0.003	0.997	0.000
I44.2 Atrioventricular block, complete	0.000	0.997	0.003
N18.4 Chronic kidney disease, stage 4	0.000	0.997	0.003
N60.0 Solitary cyst of breast	0.000	0.997	0.003
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.002	0.997	0.000
E10.1 With ketoacidosis	0.000	0.997	0.002
H93 Other disorders of ear, not elsewhere classified	0.003	0.997	0.000
E10.8 With unspecified complications	0.000	0.997	0.002
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.997	0.002
M81.1 Postoophorectomy osteoporosis	0.000	0.997	0.002
N05.1 Focal and segmental glomerular lesions	0.000	0.997	0.002
M81.0 Postmenopausal osteoporosis	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
E10.2 With renal complications	0.000	0.998	0.002
H93.9 Disorder of ear, unspecified	0.002	0.998	0.000
H93.8 Other specified disorders of ear	0.002	0.998	0.000
M81.8 Other osteoporosis	0.000	0.998	0.002
M81.6 Localised osteoporosis [Lequesne]	0.000	0.998	0.002
M81.5 Idiopathic osteoporosis	0.000	0.998	0.002
O70.9 Perineal laceration during delivery, unspecified	0.002	0.998	0.000
Q23.1 Congenital insufficiency of aortic valve	0.000	0.998	0.002
T82.1 Mechanical complication of cardiac electronic device	0.000	0.998	0.002
M89.81 Other specified disorders of bone (Shoulder region)	0.000	0.998	0.002
T78.2 Anaphylactic shock, unspecified	0.000	0.998	0.002
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.998	0.002
K70.1 Alcoholic hepatitis	0.000	0.998	0.002
M81.2 Osteoporosis of disuse	0.000	0.998	0.002
N05.2 Diffuse membranous glomerulonephritis	0.000	0.998	0.002
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.998	0.002
J35.1 Hypertrophy of tonsils	0.002	0.998	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.998	0.002
H93.3 Disorders of acoustic nerve	0.002	0.998	0.000
O70.1 Second degree perineal laceration during delivery	0.002	0.998	0.000
H60-H62 Diseases of external ear	0.002	0.998	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.998	0.002
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.998	0.002
M77.91 Enthesopathy, unspecified (Shoulder region)	0.002	0.998	0.000
M89.0 Algoneurodystrophy	0.000	0.998	0.002
T82.3 Mechanical complication of other vascular grafts	0.000	0.998	0.002
M89.03 Algoneurodystrophy (Forearm)	0.000	0.998	0.002
I44.3 Other and unspecified atrioventricular block	0.000	0.998	0.002
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.998	0.002
H93.2 Other abnormal auditory perceptions	0.002	0.998	0.000
H61 Other disorders of external ear	0.002	0.998	0.000
O70 Perineal laceration during delivery	0.002	0.998	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.000	0.998	0.002
M89.80 Other specified disorders of bone (Multiple sites)	0.000	0.998	0.002
I51.0 Cardiac septal defect, acquired	0.000	0.998	0.002
N05.6 Dense deposit disease	0.000	0.998	0.002
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.998	0.002
N05.0 Minor glomerular abnormality	0.000	0.998	0.002
M89.89 Other specified disorders of bone (Site unspecified)	0.000	0.998	0.002
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.998	0.002
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.998	0.002
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.998	0.002
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.998	0.002
E10.5 With peripheral circulatory complications	0.000	0.998	0.002
I44.5 Left posterior fascicular block	0.000	0.998	0.002
H50.9 Strabismus, unspecified	0.000	0.998	0.002
O70.2 Third degree perineal laceration during delivery	0.002	0.998	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.998	0.002
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.998	0.002
M89.83 Other specified disorders of bone (Forearm)	0.000	0.998	0.002
E10.6 With other specified complications	0.000	0.998	0.002
I51.7 Cardiomegaly	0.000	0.998	0.002
I51.5 Myocardial degeneration	0.000	0.998	0.002
M81.4 Drug-induced osteoporosis	0.000	0.998	0.002
M89.04 Algoneurodystrophy (Hand)	0.000	0.998	0.002
N05.7 Diffuse crescentic glomerulonephritis	0.000	0.998	0.002
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.998	0.002
G55.2 Nerve root and plexus compressions in spondylosis	0.002	0.998	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.002	0.998	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.998	0.002
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.998	0.002
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.998	0.002
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.998	0.002
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.998	0.002
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.998	0.002
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.998	0.002
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.998	0.002
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.998	0.002
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.998	0.002
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.998	0.002
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.998	0.002
H93.0 Degenerative and vascular disorders of ear	0.002	0.998	0.000
I44.6 Other and unspecified fascicular block	0.000	0.998	0.002
H90-H95 Other disorders of ear	0.002	0.998	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.998	0.002
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.998	0.002
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.998	0.002
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.998	0.002
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.998	0.002
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.998	0.002
M81.80 Other osteoporosis (Multiple sites)	0.000	0.998	0.002
E10.7 With multiple complications	0.000	0.998	0.002
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.998	0.002
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.58 Idiopathic osteoporosis (Other)	0.000	0.998	0.002
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.998	0.002
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.998	0.002
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.998	0.002
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.998	0.002
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.998	0.002
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.998	0.002
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.998	0.002
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.998	0.002
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.998	0.002
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.998	0.002
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.998	0.002
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.998	0.002
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.998	0.002
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.998	0.002
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.998	0.002
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.998	0.002
M81.88 Other osteoporosis (Other)	0.000	0.998	0.002
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.86 Other osteoporosis (Lower leg)	0.000	0.998	0.002
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.84 Other osteoporosis (Hand)	0.000	0.998	0.002
M81.83 Other osteoporosis (Forearm)	0.000	0.998	0.002
M81.82 Other osteoporosis (Upper arm)	0.000	0.998	0.002
M81.81 Other osteoporosis (Shoulder region)	0.000	0.998	0.002
M89.06 Algoneurodystrophy (Lower leg)	0.000	0.998	0.002
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.998	0.002
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.998	0.002
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.998	0.002
M89.01 Algoneurodystrophy (Shoulder region)	0.000	0.998	0.002
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.998	0.002
M81.89 Other osteoporosis (Site unspecified)	0.000	0.998	0.002
M89.84 Other specified disorders of bone (Hand)	0.000	0.998	0.002
I44.4 Left anterior fascicular block	0.000	0.998	0.002
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.998	0.002
M81.28 Osteoporosis of disuse (Other)	0.000	0.998	0.002
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.998	0.002
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.998	0.002
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.998	0.002
M81.24 Osteoporosis of disuse (Hand)	0.000	0.998	0.002
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.998	0.002
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.998	0.002
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.998	0.002
I51.6 Cardiovascular disease, unspecified	0.000	0.998	0.002
M89.07 Algoneurodystrophy (Ankle and foot)	0.000	0.998	0.002
T18.1 Foreign body in oesophagus	0.002	0.998	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.998	0.002
M89.09 Algoneurodystrophy (Site unspecified)	0.000	0.998	0.002
E10.0 With coma	0.000	0.998	0.002
H61.0 Perichondritis of external ear	0.002	0.998	0.000
I51.9 Heart disease, unspecified	0.000	0.998	0.002
O02.1 Missed abortion	0.000	0.998	0.002
S89.9 Unspecified injury of lower leg	0.000	0.998	0.002
M89.08 Algoneurodystrophy (Other)	0.000	0.998	0.002
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.000	0.998	0.002
M89.02 Algoneurodystrophy (Upper arm)	0.000	0.998	0.002
M89.00 Algoneurodystrophy (Multiple sites)	0.000	0.998	0.002
H50.5 Heterophoria	0.000	0.998	0.002
M25.47 Effusion of joint (Ankle and foot)	0.000	0.998	0.002
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
N30.8 Other cystitis	0.002	0.998	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.998	0.002
F03 Unspecified dementia	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.000	0.998	0.002
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.998	0.002
M11.2 Other chondrocalcinosis	0.002	0.998	0.000
O70.3 Fourth degree perineal laceration during delivery	0.002	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.000	0.998	0.002
M89 Other disorders of bone	0.000	0.998	0.002
O62.2 Other uterine inertia	0.002	0.998	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
M81.48 Drug-induced osteoporosis (Other)	0.000	0.998	0.002
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.998	0.002
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.998	0.002
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.998	0.002
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.998	0.002
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.998	0.002
R00.1 Bradycardia, unspecified	0.000	0.998	0.002
Z49.1 Extracorporeal dialysis	0.000	0.998	0.002
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
M70.6 Trochanteric bursitis	0.002	0.998	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.000	0.998	0.002
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.998	0.002
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.000	0.998	0.002
M89.88 Other specified disorders of bone (Other)	0.000	0.998	0.001
H94 Other disorders of ear in diseases classified elsewhere	0.002	0.998	0.000
H91.8 Other specified hearing loss	0.002	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.000	0.998	0.002
Q23.0 Congenital stenosis of aortic valve	0.000	0.998	0.002
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
H61.9 Disorder of external ear, unspecified	0.002	0.998	0.000
H61.8 Other specified disorders of external ear	0.002	0.998	0.000
I21.4 Acute subendocardial myocardial infarction	0.002	0.998	0.000
I37.1 Pulmonary valve insufficiency	0.000	0.998	0.002
M11.27 Other chondrocalcinosis (Ankle and foot)	0.002	0.998	0.000
N92.4 Excessive bleeding in the premenopausal period	0.002	0.998	0.000
K81.0 Acute cholecystitis	0.002	0.998	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.002	0.998	0.000
M70.69 Trochanteric bursitis-Site unspec	0.002	0.998	0.000
C22.0 Liver cell carcinoma	0.000	0.998	0.002
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.002	0.998	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.002	0.998	0.000
H93.1 Tinnitus	0.002	0.998	0.000
I51.4 Myocarditis, unspecified	0.000	0.998	0.001
H50 Other strabismus	0.000	0.998	0.002
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.001
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.000	0.998	0.001
E83.3 Disorders of phosphorus metabolism	0.002	0.998	0.000
F05.1 Delirium superimposed on dementia	0.002	0.998	0.000
S62.2 Fracture of first metacarpal bone	0.000	0.998	0.002
M54.16 Radiculopathy (Lumbar region)	0.002	0.998	0.000
F02.0 Dementia in Pick's disease	0.002	0.998	0.000
F02 Dementia in other diseases classified elsewhere	0.002	0.998	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.001	0.998	0.000
M11.28 Other chondrocalcinosis (Other)	0.001	0.998	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.001	0.998	0.000
M11.24 Other chondrocalcinosis (Hand)	0.001	0.998	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.001	0.998	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.001	0.998	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.998	0.001
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.998	0.001
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.998	0.001
Q23.4 Hypoplastic left heart syndrome	0.000	0.998	0.001
Q23.2 Congenital mitral stenosis	0.000	0.998	0.001
M11.21 Other chondrocalcinosis (Shoulder region)	0.001	0.998	0.000
M79.11 Myalgia (Shoulder region)	0.000	0.998	0.002
F06.2 Organic delusional [schizophrenia-like] disorder	0.001	0.998	0.000
I46.0 Cardiac arrest with successful resuscitation	0.000	0.998	0.002
M89.6 Osteopathy after poliomyelitis	0.000	0.998	0.001
M89.2 Other disorders of bone development and growth	0.000	0.998	0.001
M89.1 Epiphyseal arrest	0.000	0.998	0.001
F05 Delirium, not induced by alcohol and other psychoactive substances	0.002	0.998	0.000
H60 Otitis externa	0.002	0.998	0.000
I46 Cardiac arrest	0.000	0.998	0.002
M11.23 Other chondrocalcinosis (Forearm)	0.001	0.998	0.000
F06.7 Mild cognitive disorder	0.002	0.998	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.001	0.998	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.001	0.998	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
H62.2 Otitis externa in mycoses	0.001	0.998	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.001	0.998	0.000
H91.3 Deaf mutism, not elsewhere classified	0.002	0.998	0.000
Z94.0 Kidney transplant status	0.000	0.998	0.002
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.001	0.998	0.000
D09.0 Bladder	0.002	0.998	0.000
I44.1 Atrioventricular block, second degree	0.000	0.998	0.002
O70.0 First degree perineal laceration during delivery	0.002	0.998	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.998	0.002
Y42.9 Other and unspecified hormone antagonists	0.000	0.998	0.001
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.001
H91 Other hearing loss	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.001	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.001	0.998	0.000
M70.68 Trochanteric bursitis-Other	0.001	0.998	0.000
M70.67 Trochanteric bursitis-Ankle/Foot	0.001	0.998	0.000
M70.66 Trochanteric bursitis-Lower Leg	0.001	0.998	0.000
M70.64 Trochanteric bursitis-Hand	0.001	0.998	0.000
M70.63 Trochanteric bursitis-Forearm	0.001	0.998	0.000
M70.62 Trochanteric bursitis-Upper arm	0.001	0.998	0.000
M70.61 Trochanteric bursitis-Shldr region	0.001	0.998	0.000
M70.60 Trochanteric bursitis-Mult sites	0.001	0.998	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.000	0.998	0.001
M89.48 Other hypertrophic osteoarthropathy (Other)	0.000	0.998	0.001
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.000	0.998	0.001
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.000	0.998	0.001
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.000	0.998	0.001
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.000	0.998	0.001
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.000	0.998	0.001
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.000	0.998	0.001
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.000	0.998	0.001
F02.3 Dementia in Parkinson's disease	0.001	0.998	0.000
M89.5 Osteolysis	0.000	0.998	0.001
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.000	0.998	0.001
H50.2 Vertical strabismus	0.000	0.998	0.001
H60.0 Abscess of external ear	0.001	0.998	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.001	0.998	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.002	0.998	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.001	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.998	0.002
R49 Voice disturbances	0.000	0.998	0.001
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.001	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.998	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.998	0.002
F06.6 Organic emotionally labile [asthenic] disorder	0.001	0.998	0.000
F06.5 Organic dissociative disorder	0.001	0.998	0.000
F06.4 Organic anxiety disorder	0.001	0.998	0.000
F06.3 Organic mood [affective] disorders	0.001	0.998	0.000
F06.1 Organic catatonic disorder	0.001	0.998	0.000
F06.0 Organic hallucinosis	0.001	0.998	0.000
I46.1 Sudden cardiac death, so described	0.000	0.998	0.001
O69.1 Labour and delivery complicated by cord around neck, with compression	0.002	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.001	0.998	0.000
H50.6 Mechanical strabismus	0.000	0.998	0.001
H91.0 Ototoxic hearing loss	0.001	0.998	0.000
H95.1 Other disorders following mastoidectomy	0.001	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.001
I37 Pulmonary valve disorders	0.000	0.998	0.001
O73 Retained placenta and membranes, without haemorrhage	0.001	0.998	0.000
N10-N16 Renal tubulo-interstitial diseases	0.000	0.998	0.002
F05.8 Other delirium	0.001	0.998	0.000
O72.0 Third-stage haemorrhage	0.001	0.998	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
Y42.4 Oral contraceptives	0.000	0.998	0.001
Y42.2 Antithyroid drugs	0.000	0.998	0.001
F00-F09 Organic, including symptomatic, mental disorders	0.002	0.998	0.000
O60-O75 Complications of labour and delivery	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.001	0.999	0.000
A63.0 Anogenital (venereal) warts	0.001	0.999	0.000
H50.3 Intermittent heterotropia	0.000	0.999	0.001
H61.3 Acquired stenosis of external ear canal	0.001	0.999	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.001	0.999	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.001	0.999	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.999	0.001
O66 Other obstructed labour	0.001	0.999	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.999	0.001
S62.21 Fracture of first metacarpal bone (open)	0.000	0.999	0.001
F05.0 Delirium not superimposed on dementia, so described	0.001	0.999	0.000
H50.8 Other specified strabismus	0.000	0.999	0.001
H50.4 Other and unspecified heterotropia	0.000	0.999	0.001
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.001	0.999	0.000
M06.0 Seronegative rheumatoid arthritis	0.001	0.999	0.000
M89.3 Hypertrophy of bone	0.000	0.999	0.001
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.001	0.999	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.001	0.999	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.001	0.999	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.001	0.999	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.001	0.999	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.001	0.999	0.000
F02.2 Dementia in Huntington's disease	0.001	0.999	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.001	0.999	0.000
I35.8 Other aortic valve disorders	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations