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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1653608
log Bayes Factor = 16.5227
Chromosome 12   position 121,706,733  (GRCh37) Explore rs1653608 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
Chapter VIII Diseases of the ear and mastoid process
0.994 0.006 0.000
S09 Other and unspecified injuries of head
0.992 0.008 0.000
Chapter IX Diseases of the circulatory system
0.992 0.008 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.989 0.011 0.000
I30-I52 Other forms of heart disease
0.988 0.012 0.000
S09.9 Unspecified injury of head
0.987 0.013 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.981 0.019 0.000
S00 Superficial injury of head
0.979 0.021 0.000
Chapter V Mental and behavioural disorders
0.979 0.021 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.977 0.023 0.000
S01 Open wound of head
0.967 0.033 0.000
Chapter XIV Diseases of the genitourinary system
0.965 0.035 0.000
H90-H95 Other disorders of ear
0.960 0.040 0.000
Z04 Examination and observation for other reasons
0.947 0.053 0.000
N30-N39 Other diseases of urinary system
0.946 0.054 0.000
R50-R69 General symptoms and signs
0.944 0.056 0.000
M20-M25 Other joint disorders
0.942 0.058 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.940 0.060 0.000
N17-N19 Renal failure
0.940 0.060 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.938 0.062 0.000
S02 Fracture of skull and facial bones
0.937 0.063 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.937 0.063 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.934 0.066 0.000
M25 Other joint disorders, not elsewhere classified
0.931 0.069 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.931 0.069 0.000
I35 Nonrheumatic aortic valve disorders
0.931 0.069 0.000
O60-O75 Complications of labour and delivery
0.923 0.077 0.000
M25.5 Pain in joint
0.923 0.077 0.000
S40-S49 Injuries to the shoulder and upper arm
0.921 0.079 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.921 0.079 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.915 0.085 0.000
Z12 Special screening examination for neoplasms
0.915 0.085 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.913 0.087 0.000
H65-H75 Diseases of middle ear and mastoid
0.912 0.088 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.912 0.088 0.000
S20-S29 Injuries to the thorax
0.910 0.089 0.000
N18 Chronic renal failure
0.910 0.090 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.909 0.091 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.904 0.096 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.903 0.097 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.900 0.100 0.000
R19.5 Other fecal abnormalities
0.897 0.103 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.893 0.107 0.000
I51 Complications and ill-defined descriptions of heart disease
0.893 0.107 0.000
H60-H62 Diseases of external ear
0.891 0.109 0.000
S60-S69 Injuries to the wrist and hand
0.890 0.110 0.000
Chapter VI Diseases of the nervous system
0.887 0.113 0.000
Z34 Supervision of normal pregnancy
0.886 0.114 0.000
R15 Faecal incontinence
0.884 0.116 0.000
N30 Cystitis
0.884 0.116 0.000
N32 Other disorders of bladder
0.882 0.118 0.000
S00.9 Superficial injury of head, part unspecified
0.879 0.121 0.000
S50-S59 Injuries to the elbow and forearm
0.878 0.122 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.877 0.123 0.000
M50-M54 Other dorsopathies
0.874 0.126 0.000
H92 Otalgia and effusion of ear
0.873 0.127 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.871 0.129 0.000
R42 Dizziness and giddiness
0.868 0.132 0.000
S01.8 Open wound of other parts of head
0.866 0.134 0.000
S00.1 Contusion of eyelid and periocular area
0.862 0.138 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.861 0.139 0.000
R52 Pain, not elsewhere classified
0.861 0.139 0.000
O36 Maternal care for other known or suspected foetal problems
0.860 0.140 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.860 0.140 0.000
R47-R49 Symptoms and signs involving speech and voice
0.859 0.141 0.000
O32.1 Maternal care for breech presentation
0.855 0.145 0.000
I45 Other conduction disorders
0.854 0.146 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.851 0.149 0.000
Z04.8 Examination and observation for other specified reasons
0.850 0.150 0.000
S00.8 Superficial injury of other parts of head
0.850 0.150 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.848 0.152 0.000
Chapter XX External causes of morbidity and mortality
0.847 0.153 0.000
R55 Syncope and collapse
0.844 0.156 0.000
I50 Heart failure
0.842 0.158 0.000
H90 Conductive and sensorineural hearing loss
0.842 0.158 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.841 0.159 0.000
I35.0 Aortic (valve) stenosis
0.840 0.160 0.000
S42 Fracture of shoulder and upper arm
0.838 0.162 0.000
R01 Cardiac murmurs and other cardiac sounds
0.838 0.162 0.000
M65-M68 Disorders of synovium and tendon
0.836 0.164 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.835 0.165 0.000
N19 Unspecified renal failure
0.835 0.165 0.000
Z36 Antenatal screening
0.834 0.166 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.834 0.166 0.000
Z04.3 Examination and observation following other accident
0.834 0.166 0.000
I51.7 Cardiomegaly
0.832 0.168 0.000
R52.2 Other chronic pain
0.831 0.169 0.000
S01.2 Open wound of nose
0.829 0.171 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.829 0.171 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.828 0.172 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.827 0.173 0.000
R30-R39 Symptoms and signs involving the urinary system
0.826 0.174 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.826 0.174 0.000
H65 Nonsuppurative otitis media
0.826 0.174 0.000
S06 Intracranial injury
0.825 0.175 0.000
Z13 Special screening examination for other diseases and disorders
0.823 0.177 0.000
M51 Other intervertebral disk disorders
0.823 0.177 0.000
Z92 Personal history of medical treatment
0.817 0.183 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.815 0.185 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.811 0.189 0.000
R04 Haemorrhage from respiratory passages
0.809 0.191 0.000
S64 Injury of nerves at wrist and hand level
0.809 0.191 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.808 0.192 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.803 0.196 0.000
I49 Other cardiac arrhythmias
0.803 0.197 0.000
R54 Senility
0.801 0.199 0.000
Q60-Q64 Congenital malformations of the urinary system
0.801 0.199 0.000
Z04.1 Examination and observation following transport accident
0.801 0.199 0.000
H92.0 Otalgia
0.800 0.200 0.000
R32 Unspecified urinary incontinence
0.795 0.205 0.000
I34 Nonrheumatic mitral valve disorders
0.794 0.206 0.000
S27 Injury of other and unspecified intrathoracic organs
0.792 0.208 0.000
R33 Retention of urine
0.791 0.209 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.789 0.211 0.000
O20 Haemorrhage in early pregnancy
0.789 0.211 0.000
S01.5 Open wound of lip and oral cavity
0.787 0.213 0.000
R63 Symptoms and signs concerning food and fluid intake
0.786 0.214 0.000
G90-G99 Other disorders of the nervous system
0.786 0.214 0.000
M25.56 Pain in joint (Lower leg)
0.785 0.215 0.000
S02.1 Fracture of base of skull
0.784 0.216 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.784 0.216 0.000
W00-W19 Falls
0.783 0.217 0.000
I50.0 Congestive heart failure
0.782 0.218 0.000
R04.2 Haemoptysis
0.780 0.220 0.000
N30.9 Cystitis, unspecified
0.779 0.221 0.000
R01.1 Cardiac murmur, unspecified
0.779 0.221 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.778 0.222 0.000
S01.1 Open wound of eyelid and periocular area
0.777 0.223 0.000
F10.3 Withdrawal state
0.777 0.223 0.000
I42 Cardiomyopathy
0.776 0.224 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.776 0.224 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.775 0.225 0.000
R05 Cough
0.775 0.225 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.774 0.226 0.000
O46.9 Antepartum haemorrhage, unspecified
0.774 0.226 0.000
F10.2 Dependence syndrome
0.773 0.227 0.000
N18.9 Chronic renal failure, unspecified
0.773 0.227 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.772 0.228 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.771 0.229 0.000
S52 Fracture of forearm
0.771 0.229 0.000
Chapter X Diseases of the respiratory system
0.770 0.230 0.000
O72 Postpartum haemorrhage
0.770 0.230 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.770 0.230 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.769 0.231 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.768 0.232 0.000
H61 Other disorders of external ear
0.767 0.233 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.767 0.233 0.000
I05-I09 Chronic rheumatic heart diseases
0.766 0.234 0.000
H91 Other hearing loss
0.766 0.234 0.000
R61 Hyperhidrosis
0.766 0.234 0.000
Chapter VII Diseases of the eye and adnexa
0.764 0.236 0.000
N18.3 Chronic kidney disease, stage 3
0.764 0.236 0.000
N18.0 End-stage renal disease
0.763 0.237 0.000
I46 Cardiac arrest
0.763 0.237 0.000
F10.0 Acute intoxication
0.762 0.238 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.760 0.240 0.000
I37 Pulmonary valve disorders
0.760 0.240 0.000
S02.0 Fracture of vault of skull
0.759 0.241 0.000
N32.3 Diverticulum of bladder
0.758 0.242 0.000
M80-M85 Disorders of bone density and structure
0.757 0.243 0.000
S02.2 Fracture of nasal bones
0.757 0.243 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.757 0.243 0.000
M91-M94 Chondropathies
0.757 0.243 0.000
T79-T79 Certain early complications of trauma
0.757 0.243 0.000
I35.8 Other aortic valve disorders
0.757 0.243 0.000
S00.0 Superficial injury of scalp
0.756 0.244 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.756 0.244 0.000
M25.53 Pain in joint (Forearm)
0.756 0.244 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.754 0.246 0.000
S01.3 Open wound of ear
0.752 0.248 0.000
O48 Prolonged pregnancy
0.751 0.249 0.000
M51.2 Other specified intervertebral disk displacement
0.750 0.250 0.000
N32.0 Bladder-neck obstruction
0.750 0.250 0.000
N00-N08 Glomerular diseases
0.750 0.250 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.749 0.251 0.000
M25.59 Pain in joint (Site unspecified)
0.749 0.251 0.000
R46 Symptoms and signs involving appearance and behaviour
0.747 0.253 0.000
I10-I15 Hypertensive diseases
0.746 0.254 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.746 0.254 0.000
O85-O92 Complications predominantly related to the puerperium
0.745 0.255 0.000
N18.2 Chronic kidney disease, stage 2
0.743 0.257 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.742 0.258 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.741 0.259 0.000
H60 Otitis externa
0.740 0.259 0.000
I45.1 Other and unspecified right bundle-branch block
0.740 0.260 0.000
R40 Somnolence, stupor and coma
0.739 0.261 0.000
N99-N99 Other disorders of the genitourinary system
0.739 0.261 0.000
O16 Unspecified maternal hypertension
0.737 0.263 0.000
O30 Multiple gestation
0.736 0.264 0.000
N30.2 Other chronic cystitis
0.735 0.265 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.734 0.266 0.000
N18.5 Chronic kidney disease, stage 5
0.734 0.266 0.000
R51 Headache
0.734 0.266 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.733 0.267 0.000
M67 Other disorders of synovium and tendon
0.733 0.267 0.000
J40-J47 Chronic lower respiratory diseases
0.733 0.267 0.000
N34 Urethritis and urethral syndrome
0.732 0.267 0.000
Z37 Outcome of delivery
0.733 0.267 0.000
I38 Endocarditis, valve unspecified
0.731 0.269 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.730 0.270 0.000
I60-I69 Cerebrovascular diseases
0.730 0.270 0.000
S42.3 Fracture of shaft of humerus
0.730 0.270 0.000
S01.4 Open wound of cheek and temporomandibular area
0.729 0.271 0.000
M24 Other specific joint derangements
0.729 0.271 0.000
S64.4 Injury of digital nerve of other finger
0.728 0.272 0.000
S02.4 Fracture of malar and maxillary bones
0.728 0.272 0.000
G20-G26 Extrapyramidal and movement disorders
0.728 0.272 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.727 0.273 0.000
R68 Other general symptoms and signs
0.726 0.274 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.726 0.274 0.000
O43 Placental disorders
0.724 0.275 0.000
M21 Other acquired deformities of limbs
0.724 0.276 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.723 0.277 0.000
O36.8 Maternal care for other specified foetal problems
0.723 0.277 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.723 0.277 0.000
M25.8 Other specified joint disorders
0.722 0.278 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.721 0.279 0.000
S00.3 Superficial injury of nose
0.721 0.279 0.000
S42.1 Fracture of scapula
0.720 0.280 0.000
Chapter XXII Codes for special purposes
0.720 0.280 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.719 0.281 0.000
F60-F69 Disorders of adult personality and behaviour
0.718 0.282 0.000
Z35 Supervision of high-risk pregnancy
0.718 0.282 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
S08 Traumatic amputation of part of head
0.717 0.283 0.000
S07 Crushing injury of head
0.717 0.283 0.000
S05 Injury of eye and orbit
0.717 0.283 0.000
S04 Injury of cranial nerves
0.717 0.283 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.717 0.283 0.000
Z34.8 Supervision of other normal pregnancy
0.717 0.283 0.000
H65.3 Chronic mucoid otitis media
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
S90-S99 Injuries to the ankle and foot
0.716 0.284 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.716 0.284 0.000
I51.8 Other ill-defined heart diseases
0.715 0.285 0.000
O32.8 Maternal care for other malpresentation of foetus
0.714 0.286 0.000
F10.1 Harmful use
0.714 0.286 0.000
M45-M49 Spondylopathies
0.713 0.286 0.000
S09.8 Other specified injuries of head
0.711 0.288 0.000
S09.7 Multiple injuries of head
0.711 0.288 0.000
S09.2 Traumatic rupture of ear drum
0.711 0.288 0.000
S09.1 Injury of muscle and tendon of head
0.711 0.288 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.711 0.288 0.000
T93 Sequelae of injuries of lower limb
0.711 0.289 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.711 0.289 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.711 0.289 0.000
I00-I02 Acute rheumatic fever
0.711 0.289 0.000
J44 Other chronic obstructive pulmonary disease
0.710 0.290 0.000
S40 Superficial injury of shoulder and upper arm
0.710 0.290 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.710 0.290 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.710 0.290 0.000
T90 Sequelae of injuries of head
0.710 0.290 0.000
N30.1 Interstitial cystitis (chronic)
0.710 0.290 0.000
Z10 Routine general health check-up of defined subpopulation
0.709 0.291 0.000
M40-M43 Deforming dorsopathies
0.709 0.291 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.709 0.291 0.000
Z36.8 Other antenatal screening
0.709 0.291 0.000
H93 Other disorders of ear, not elsewhere classified
0.709 0.291 0.000
I52 Other heart disorders in diseases classified elsewhere
0.709 0.291 0.000
I48 Atrial fibrillation and flutter
0.709 0.291 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.709 0.291 0.000
I41 Myocarditis in diseases classified elsewhere
0.709 0.291 0.000
I40 Acute myocarditis
0.709 0.291 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.709 0.291 0.000
I36 Nonrheumatic tricuspid valve disorders
0.709 0.291 0.000
I32 Pericarditis in diseases classified elsewhere
0.709 0.291 0.000
I30 Acute pericarditis
0.709 0.291 0.000
M25.3 Other instability of joint
0.708 0.292 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.707 0.293 0.000
I33 Acute and subacute endocarditis
0.707 0.293 0.000
O41 Other disorders of amniotic fluid and membranes
0.707 0.293 0.000
R63.0 Anorexia
0.706 0.294 0.000
R49 Voice disturbances
0.706 0.294 0.000
O45 Premature separation of placenta [abruptio placentae]
0.703 0.297 0.000
O44 Placenta praevia
0.703 0.297 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.703 0.297 0.000
O33 Maternal care for known or suspected disproportion
0.703 0.297 0.000
O31 Complications specific to multiple gestation
0.703 0.297 0.000
O40 Polyhydramnios
0.703 0.297 0.000
S20 Superficial injury of thorax
0.703 0.297 0.000
S00.7 Multiple superficial injuries of head
0.702 0.298 0.000
S00.5 Superficial injury of lip and oral cavity
0.702 0.298 0.000
S00.4 Superficial injury of ear
0.702 0.298 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.702 0.298 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.702 0.298 0.000
F70-F79 Mental retardation
0.702 0.298 0.000
M86-M90 Other osteopathies
0.701 0.299 0.000
I35.1 Aortic (valve) insufficiency
0.701 0.299 0.000
M60-M63 Disorders of muscles
0.700 0.300 0.000
M00-M03 Infectious arthropathies
0.700 0.300 0.000
R47 Speech disturbances, not elsewhere classified
0.700 0.300 0.000
S02.5 Fracture of tooth
0.699 0.301 0.000
G30-G32 Other degenerative diseases of the nervous system
0.699 0.301 0.000
I34.1 Mitral (valve) prolapse
0.699 0.301 0.000
H73 Other disorders of tympanic membrane
0.698 0.302 0.000
R60 Oedema, not elsewhere classified
0.698 0.302 0.000
O70 Perineal laceration during delivery
0.698 0.302 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.698 0.302 0.000
Z36.9 Antenatal screening, unspecified
0.697 0.303 0.000
S52.5 Fracture of lower end of radius
0.697 0.303 0.000
Q50-Q56 Congenital malformations of genital organs
0.696 0.304 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.696 0.304 0.000
S02.6 Fracture of mandible
0.696 0.304 0.000
H66 Suppurative and unspecified otitis media
0.696 0.304 0.000
N36 Other disorders of urethra
0.695 0.305 0.000
Z82.3 Family history of stroke
0.694 0.306 0.000
S01.7 Multiple open wounds of head
0.693 0.307 0.000
H80-H83 Diseases of inner ear
0.693 0.307 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.692 0.308 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.692 0.308 0.000
M35 Other systemic involvement of connective tissue
0.691 0.309 0.000
O63 Long labour
0.689 0.310 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.689 0.311 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.689 0.311 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.688 0.312 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.688 0.312 0.000
F80-F89 Disorders of psychological development
0.688 0.312 0.000
S29 Other and unspecified injuries of thorax
0.687 0.313 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.687 0.313 0.000
O20.0 Threatened abortion
0.687 0.313 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.687 0.313 0.000
Q63 Other congenital malformations of kidney
0.687 0.313 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.686 0.314 0.000
F01 Vascular dementia
0.686 0.314 0.000
N30.8 Other cystitis
0.686 0.314 0.000
Z34.0 Supervision of normal first pregnancy
0.686 0.314 0.000
M25.7 Osteophyte
0.685 0.315 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.685 0.315 0.000
I49.4 Other and unspecified premature depolarisation
0.685 0.315 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.684 0.316 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.683 0.316 0.000
W18 Other fall on same level
0.683 0.317 0.000
H90.2 Conductive hearing loss, unspecified
0.682 0.318 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.682 0.318 0.000
Z98 Other postsurgical states
0.681 0.319 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.681 0.319 0.000
Q80-Q89 Other congenital malformations
0.680 0.320 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.680 0.320 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.679 0.321 0.000
Z04.6 General psychiatric examination, requested by authority
0.679 0.321 0.000
Z04.5 Examination and observation following other inflicted injury
0.679 0.321 0.000
Z04.4 Examination and observation following alleged rape and seduction
0.679 0.321 0.000
Z04.2 Examination and observation following work accident
0.679 0.321 0.000
Z04.0 Blood-alcohol and blood-drug test
0.679 0.321 0.000
M25.51 Pain in joint (Shoulder region)
0.679 0.321 0.000
N37 Urethral disorders in diseases classified elsewhere
0.679 0.321 0.000
N33 Bladder disorders in diseases classified elsewhere
0.679 0.321 0.000
O66 Other obstructed labour
0.677 0.323 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.677 0.323 0.000
R62 Lack of expected normal physiological development
0.677 0.323 0.000
R57 Shock, not elsewhere classified
0.677 0.323 0.000
R64 Cachexia
0.677 0.323 0.000
R58 Haemorrhage, not elsewhere classified
0.677 0.323 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.675 0.324 0.000
M34 Systemic sclerosis
0.675 0.324 0.000
M33 Dermatopolymyositis
0.675 0.324 0.000
M32 Systemic lupus erythematosus
0.675 0.324 0.000
M30 Polyarteritis nodosa and related conditions
0.675 0.324 0.000
I35.9 Aortic valve disorder, unspecified
0.675 0.325 0.000
Q66 Congenital deformities of feet
0.675 0.325 0.000
N32.8 Other specified disorders of bladder
0.675 0.325 0.000
M22 Disorders of patella
0.675 0.325 0.000
S02.10 Fracture of base of skull (closed)
0.675 0.325 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.674 0.326 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.674 0.326 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.674 0.326 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.674 0.326 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.674 0.326 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.674 0.326 0.000
F11 Mental and behavioural disorders due to use of opioids
0.674 0.326 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.674 0.326 0.000
Z13.5 Special screening examination for eye and ear disorders
0.674 0.326 0.000
Z38 Liveborn infants according to place of birth
0.673 0.327 0.000
Z32 Pregnancy examination and test
0.673 0.327 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.673 0.327 0.000
F99-F99 Unspecified mental disorder
0.673 0.327 0.000
H72 Perforation of tympanic membrane
0.672 0.328 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.672 0.328 0.000
O80-O84 Delivery
0.672 0.328 0.000
I45.2 Bifascicular block
0.672 0.328 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.672 0.328 0.000
S02.8 Fractures of other skull and facial bones
0.672 0.328 0.000
S02.7 Multiple fractures involving skull and facial bones
0.672 0.328 0.000
S02.3 Fracture of orbital floor
0.672 0.328 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.671 0.328 0.000
Z09.4 Follow-up examination after treatment of fracture
0.671 0.328 0.000
Z09.3 Follow-up examination after psychotherapy
0.671 0.328 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.671 0.328 0.000
I20-I25 Ischaemic heart diseases
0.671 0.329 0.000
V80-V89 Other land transport accidents
0.671 0.329 0.000
H90.3 Sensorineural hearing loss, bilateral
0.671 0.329 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.670 0.330 0.000
S27.3 Other injuries of lung
0.670 0.330 0.000
R43 Disturbances of smell and taste
0.670 0.330 0.000
Z31 Procreative management
0.669 0.331 0.000
I50.9 Heart failure, unspecified
0.668 0.332 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.667 0.332 0.000
M25.9 Joint disorder, unspecified
0.667 0.333 0.000
M25.2 Flail joint
0.667 0.333 0.000
M25.1 Fistula of joint
0.667 0.333 0.000
M25.0 Haemarthrosis
0.667 0.333 0.000
O15 Eclampsia
0.667 0.333 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.667 0.333 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.667 0.333 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.667 0.333 0.000
M25.57 Pain in joint (Ankle and foot)
0.666 0.333 0.000
H92.1 Otorrhoea
0.666 0.334 0.000
Z94 Transplanted organ and tissue status
0.664 0.336 0.000
R07 Pain in throat and chest
0.664 0.336 0.000
N76 Other inflammation of vagina and vulva
0.663 0.337 0.000
S06.2 Diffuse brain injury
0.663 0.337 0.000
O74 Complications of anaesthesia during labour and delivery
0.662 0.338 0.000
O71 Other obstetric trauma
0.662 0.338 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.662 0.338 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.662 0.338 0.000
O62 Abnormalities of forces of labour
0.662 0.338 0.000
O61 Failed induction of labour
0.662 0.338 0.000
O60 Preterm delivery
0.662 0.338 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.661 0.338 0.000
M25.58 Pain in joint (Other)
0.661 0.338 0.000
M25.52 Pain in joint (Upper arm)
0.661 0.338 0.000
Chapter I Certain infectious and parasitic diseases
0.661 0.339 0.000
S48 Traumatic amputation of shoulder and upper arm
0.660 0.340 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.660 0.340 0.000
S44 Injury of nerves at shoulder and upper arm level
0.660 0.340 0.000
S41 Open wound of shoulder and upper arm
0.660 0.340 0.000
S47 Crushing injury of shoulder and upper arm
0.660 0.340 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.660 0.340 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.660 0.340 0.000
M53 Other dorsopathies, not elsewhere classified
0.659 0.341 0.000
T66-T78 Other and unspecified effects of external causes
0.659 0.341 0.000
M67.8 Other specified disorders of synovium and tendon
0.659 0.341 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.659 0.341 0.000
N73 Other female pelvic inflammatory diseases
0.658 0.342 0.000
N32.1 Vesicointestinal fistula
0.658 0.342 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.657 0.343 0.000
G93 Other disorders of brain
0.657 0.343 0.000
S51 Open wound of forearm
0.656 0.344 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.656 0.344 0.000
O32.6 Maternal care for compound presentation
0.656 0.344 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.656 0.344 0.000
O32.4 Maternal care for high head at term
0.656 0.344 0.000
O32.3 Maternal care for face, brow and chin presentation
0.656 0.344 0.000
O32.2 Maternal care for transverse and oblique lie
0.656 0.344 0.000
O32.0 Maternal care for unstable lie
0.656 0.344 0.000
R25 Abnormal involuntary movements
0.656 0.344 0.000
O00-O08 Pregnancy with abortive outcome
0.656 0.344 0.000
Z12.9 Special screening examination for neoplasm, unspecified
0.656 0.344 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.656 0.344 0.000
Z12.6 Special screening examination for neoplasm of bladder
0.656 0.344 0.000
Z12.5 Special screening examination for neoplasm of prostate
0.656 0.344 0.000
Z12.4 Special screening examination for neoplasm of cervix
0.656 0.344 0.000
Z12.3 Special screening examination for neoplasm of breast
0.656 0.344 0.000
Z12.2 Special screening examination for neoplasm of respiratory organs
0.656 0.344 0.000
Z12.0 Special screening examination for neoplasm of stomach
0.656 0.344 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.656 0.344 0.000
O73 Retained placenta and membranes, without haemorrhage
0.655 0.345 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.655 0.345 0.000
O97 Death from sequelae of direct obstetric causes
0.655 0.345 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.655 0.345 0.000
O95 Obstetric death of unspecified cause
0.655 0.345 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.655 0.345 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.654 0.346 0.000
H74 Other disorders of middle ear and mastoid
0.654 0.346 0.000
H70 Mastoiditis and related conditions
0.654 0.346 0.000
H69 Other disorders of Eustachian tube
0.654 0.346 0.000
H68 Eustachian salpingitis and obstruction
0.654 0.346 0.000
H67 Otitis media in diseases classified elsewhere
0.654 0.346 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.654 0.346 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.654 0.346 0.000
Q35-Q37 Cleft lip and cleft palate
0.654 0.346 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.654 0.346 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.654 0.346 0.000
Q00-Q07 Congenital malformations of the nervous system
0.654 0.346 0.000
F20 Schizophrenia
0.654 0.346 0.000
S06.8 Other intracranial injuries
0.654 0.346 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.653 0.347 0.000
S26 Injury of heart
0.653 0.347 0.000
S25 Injury of blood vessels of thorax
0.653 0.347 0.000
S24 Injury of nerves and spinal cord at thorax level
0.653 0.347 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.653 0.347 0.000
S21 Open wound of thorax
0.653 0.347 0.000
I71 Aortic aneurysm and dissection
0.652 0.348 0.000
G40-G47 Episodic and paroxysmal disorders
0.652 0.348 0.000
N18.8 Other chronic renal failure
0.652 0.348 0.000
N18.1 Chronic kidney disease, stage 1
0.652 0.348 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.652 0.348 0.000
S42.30 Fracture of shaft of humerus (closed)
0.652 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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