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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16830359
log Bayes Factor = 1.00347
Chromosome 1   position 43,596,384  (GRCh37) Explore rs16830359 on Ensembl!
Variant rs16830359 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.897 0.103 0.000
Chapter XIV Diseases of the genitourinary system
0.896 0.104 0.000
Chapter II Neoplasms
0.887 0.113 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.869 0.131 0.000
D10-D36 Benign neoplasms
0.854 0.146 0.000
N30-N39 Other diseases of urinary system
0.832 0.168 0.000
Chapter XI Diseases of the digestive system
0.831 0.169 0.000
Chapter XXI Factors influencing health status and contact with health services
0.805 0.195 0.000
Chapter VII Diseases of the eye and adnexa
0.801 0.199 0.000
N81 Female genital prolapse
0.801 0.199 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.786 0.213 0.000
N32 Other disorders of bladder
0.785 0.215 0.000
C60-C63 Malignant neoplasms of male genital organs
0.784 0.216 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.777 0.223 0.000
K55-K64 Other diseases of intestines
0.775 0.225 0.000
N93 Other abnormal uterine and vaginal bleeding
0.773 0.227 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.757 0.243 0.000
N20-N23 Urolithiasis
0.756 0.244 0.000
N40-N51 Diseases of male genital organs
0.754 0.246 0.000
N32.8 Other specified disorders of bladder
0.740 0.260 0.000
C64-C68 Malignant neoplasms of urinary tract
0.726 0.274 0.000
N60-N64 Disorders of breast
0.724 0.276 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.718 0.282 0.000
N81.1 Cystocele
0.716 0.284 0.000
C61 Malignant neoplasm of prostate
0.710 0.290 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.705 0.295 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.704 0.296 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.701 0.299 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.700 0.300 0.000
N95 Menopausal and other perimenopausal disorders
0.696 0.304 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.696 0.304 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.694 0.306 0.000
D17 Benign lipomatous neoplasm
0.692 0.308 0.000
H25-H28 Disorders of lens
0.685 0.315 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.685 0.315 0.000
D18 Haemangioma and lymphangioma, any site
0.684 0.316 0.000
N35 Urethral stricture
0.679 0.320 0.000
K62 Other diseases of anus and rectum
0.677 0.323 0.000
K63 Other diseases of intestine
0.676 0.324 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.675 0.324 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.673 0.326 0.000
D23 Other benign neoplasms of skin
0.673 0.327 0.000
D12.5 Sigmoid colon
0.668 0.332 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.668 0.332 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.665 0.335 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.665 0.335 0.000
M50-M54 Other dorsopathies
0.664 0.335 0.000
H30-H36 Disorders of choroid and retina
0.664 0.336 0.000
K29 Gastritis and duodenitis
0.662 0.338 0.000
N10-N16 Renal tubulo-interstitial diseases
0.660 0.340 0.000
N81.4 Uterovaginal prolapse, unspecified
0.659 0.341 0.000
N80 Endometriosis
0.658 0.342 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.656 0.344 0.000
Chapter VIII Diseases of the ear and mastoid process
0.654 0.346 0.000
D27 Benign neoplasm of ovary
0.651 0.349 0.000
N23 Unspecified renal colic
0.650 0.350 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.647 0.353 0.000
Chapter XXII Codes for special purposes
0.643 0.357 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.643 0.357 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.643 0.357 0.000
N99-N99 Other disorders of the genitourinary system
0.642 0.357 0.000
N25-N29 Other disorders of kidney and ureter
0.642 0.357 0.000
N00-N08 Glomerular diseases
0.642 0.357 0.000
Z80 Family history of malignant neoplasm
0.636 0.364 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.636 0.364 0.000
D00-D09 In situ neoplasms
0.636 0.364 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.636 0.364 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.636 0.364 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.636 0.364 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.636 0.364 0.000
C51-C58 Malignant neoplasms of female genital organs
0.636 0.364 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.636 0.364 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.636 0.364 0.000
C15-C26 Malignant neoplasms of digestive organs
0.636 0.364 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.636 0.364 0.000
M20-M25 Other joint disorders
0.630 0.370 0.000
M70-M79 Other soft tissue disorders
0.629 0.371 0.000
N40 Hyperplasia of prostate
0.628 0.372 0.000
N32.3 Diverticulum of bladder
0.628 0.372 0.000
D12.6 Colon, unspecified
0.624 0.376 0.000
K30 Dyspepsia
0.624 0.376 0.000
D22 Melanocytic naevi
0.624 0.376 0.000
N98 Complications associated with artificial fertilisation
0.623 0.377 0.000
N97 Female infertility
0.623 0.377 0.000
N91 Absent, scanty and rare menstruation
0.623 0.377 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.623 0.377 0.000
N89 Other noninflammatory disorders of vagina
0.623 0.377 0.000
N88 Other noninflammatory disorders of cervix uteri
0.623 0.377 0.000
N87 Dysplasia of cervix uteri
0.623 0.377 0.000
N82 Fistulae involving female genital tract
0.623 0.377 0.000
N96 Habitual aborter
0.623 0.377 0.000
N86 Erosion and ectropion of cervix uteri
0.623 0.377 0.000
D24 Benign neoplasm of breast
0.620 0.380 0.000
Z87 Personal history of other diseases and conditions
0.619 0.381 0.000
Chapter XX External causes of morbidity and mortality
0.617 0.383 0.000
N93.0 Postcoital and contact bleeding
0.617 0.383 0.000
K61 Abscess of anal and rectal regions
0.616 0.384 0.000
M65-M68 Disorders of synovium and tendon
0.613 0.387 0.000
D36 Benign neoplasm of other and unspecified sites
0.612 0.387 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.612 0.387 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.612 0.387 0.000
D32 Benign neoplasm of meninges
0.612 0.387 0.000
D31 Benign neoplasm of eye and adnexa
0.612 0.387 0.000
D30 Benign neoplasm of urinary organs
0.612 0.387 0.000
D29 Benign neoplasm of male genital organs
0.612 0.387 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.612 0.387 0.000
D26 Other benign neoplasms of uterus
0.612 0.387 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.612 0.387 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.612 0.387 0.000
D19 Benign neoplasm of mesothelial tissue
0.612 0.387 0.000
D16 Benign neoplasm of bone and articular cartilage
0.612 0.387 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.612 0.387 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.612 0.387 0.000
D11 Benign neoplasm of major salivary glands
0.612 0.387 0.000
D10 Benign neoplasm of mouth and pharynx
0.612 0.387 0.000
D34 Benign neoplasm of thyroid gland
0.612 0.387 0.000
Z51 Other medical care
0.612 0.388 0.000
N81.6 Rectocele
0.612 0.388 0.000
D12.2 Ascending colon
0.609 0.391 0.000
K59 Other functional intestinal disorders
0.607 0.393 0.000
M45-M49 Spondylopathies
0.605 0.395 0.000
N84 Polyp of female genital tract
0.605 0.395 0.000
Chapter X Diseases of the respiratory system
0.603 0.397 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.598 0.402 0.000
K29.7 Gastritis, unspecified
0.598 0.402 0.000
K63.5 Polyp of colon
0.597 0.403 0.000
N37 Urethral disorders in diseases classified elsewhere
0.596 0.404 0.000
N36 Other disorders of urethra
0.596 0.404 0.000
N34 Urethritis and urethral syndrome
0.596 0.404 0.000
N33 Bladder disorders in diseases classified elsewhere
0.596 0.404 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.596 0.404 0.000
N30 Cystitis
0.596 0.404 0.000
K35-K38 Diseases of appendix
0.596 0.404 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.595 0.405 0.000
K70-K77 Diseases of liver
0.594 0.406 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.593 0.407 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.592 0.408 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.588 0.412 0.000
K80 Cholelithiasis
0.588 0.412 0.000
K90-K93 Other diseases of the digestive system
0.587 0.413 0.000
N94.1 Dyspareunia
0.587 0.413 0.000
K60 Fissure and fistula of anal and rectal regions
0.582 0.417 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.582 0.418 0.000
Z98 Other postsurgical states
0.581 0.419 0.000
D12.3 Transverse colon
0.580 0.420 0.000
H26 Other cataract
0.577 0.423 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.577 0.423 0.000
K65-K67 Diseases of peritoneum
0.576 0.424 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.575 0.425 0.000
H55-H59 Other disorders of eye and adnexa
0.574 0.425 0.000
H53-H54 Visual disturbances and blindness
0.574 0.425 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.574 0.425 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.574 0.425 0.000
H43-H45 Disorders of vitreous body and globe
0.574 0.425 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.574 0.425 0.000
H10-H13 Disorders of conjunctiva
0.574 0.425 0.000
N81.9 Female genital prolapse, unspecified
0.574 0.426 0.000
N81.8 Other female genital prolapse
0.574 0.426 0.000
N81.5 Vaginal enterocele
0.574 0.426 0.000
N81.3 Complete uterovaginal prolapse
0.574 0.426 0.000
N81.0 Female urethrocele
0.574 0.426 0.000
M05-M14 Inflammatory polyarthropathies
0.573 0.427 0.000
N95.0 Postmenopausal bleeding
0.572 0.428 0.000
T81 Complications of procedures, not elsewhere classified
0.572 0.428 0.000
N62 Hypertrophy of breast
0.572 0.428 0.000
K62.5 Haemorrhage of anus and rectum
0.572 0.428 0.000
N35.9 Urethral stricture, unspecified
0.571 0.429 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.570 0.430 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.569 0.430 0.000
K58 Irritable bowel syndrome
0.569 0.431 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.564 0.436 0.000
M91-M94 Chondropathies
0.564 0.436 0.000
M86-M90 Other osteopathies
0.564 0.436 0.000
M60-M63 Disorders of muscles
0.564 0.436 0.000
M40-M43 Deforming dorsopathies
0.564 0.436 0.000
M00-M03 Infectious arthropathies
0.564 0.436 0.000
N32.9 Bladder disorder, unspecified
0.563 0.437 0.000
N32.4 Rupture of bladder, nontraumatic
0.563 0.437 0.000
N32.2 Vesical fistula, not elsewhere classified
0.563 0.437 0.000
N32.1 Vesicointestinal fistula
0.563 0.437 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.562 0.438 0.000
C62 Malignant neoplasm of testis
0.562 0.438 0.000
C60 Malignant neoplasm of penis
0.562 0.438 0.000
D18.0 Haemangioma, any site
0.561 0.439 0.000
N17-N19 Renal failure
0.561 0.439 0.000
C67 Malignant neoplasm of bladder
0.560 0.440 0.000
C50-C50 Malignant neoplasm of breast
0.559 0.441 0.000
N63 Unspecified lump in breast
0.558 0.442 0.000
D12.9 Anus and anal canal
0.557 0.443 0.000
D12.7 Rectosigmoid junction
0.557 0.443 0.000
D12.4 Descending colon
0.557 0.443 0.000
D12.1 Appendix
0.557 0.443 0.000
D12.0 Caecum
0.557 0.443 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.557 0.443 0.000
Chapter VI Diseases of the nervous system
0.556 0.443 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.556 0.444 0.000
K55 Vascular disorders of intestine
0.556 0.444 0.000
S00-S09 Injuries to the head
0.555 0.444 0.000
H40-H42 Glaucoma
0.555 0.445 0.000
N50 Other disorders of male genital organs
0.555 0.445 0.000
N32.0 Bladder-neck obstruction
0.554 0.446 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.553 0.447 0.000
Z83 Family history of other specific disorders
0.552 0.448 0.000
N20 Calculus of kidney and ureter
0.552 0.448 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.551 0.449 0.000
N81.2 Incomplete uterovaginal prolapse
0.551 0.449 0.000
N85.0 Endometrial glandular hyperplasia
0.551 0.449 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.546 0.453 0.000
M54 Dorsalgia
0.546 0.454 0.000
H36 Retinal disorders in diseases classified elsewhere
0.543 0.457 0.000
D23.1 Skin of eyelid, including canthus
0.543 0.457 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.542 0.457 0.000
T79-T79 Certain early complications of trauma
0.542 0.457 0.000
T66-T78 Other and unspecified effects of external causes
0.542 0.457 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.542 0.457 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.542 0.457 0.000
T33-T35 Frostbite
0.542 0.457 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.542 0.457 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.542 0.457 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.542 0.457 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.542 0.457 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.542 0.457 0.000
T00-T07 Injuries involving multiple body regions
0.542 0.457 0.000
S90-S99 Injuries to the ankle and foot
0.542 0.457 0.000
S70-S79 Injuries to the hip and thigh
0.542 0.457 0.000
S40-S49 Injuries to the shoulder and upper arm
0.542 0.457 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.542 0.457 0.000
S20-S29 Injuries to the thorax
0.542 0.457 0.000
S10-S19 Injuries to the neck
0.542 0.457 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.542 0.458 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.542 0.458 0.000
N21 Calculus of lower urinary tract
0.542 0.458 0.000
Chapter I Certain infectious and parasitic diseases
0.541 0.458 0.000
K62.1 Rectal polyp
0.541 0.459 0.000
S60-S69 Injuries to the wrist and hand
0.541 0.459 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.541 0.459 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.541 0.459 0.000
N48 Other disorders of penis
0.541 0.459 0.000
N45 Orchitis and epididymitis
0.541 0.459 0.000
N43 Hydrocele and spermatocele
0.541 0.459 0.000
N42 Other disorders of prostate
0.541 0.459 0.000
N41 Inflammatory diseases of prostate
0.541 0.459 0.000
N46 Male infertility
0.541 0.459 0.000
N44 Torsion of testis
0.541 0.459 0.000
D12.8 Rectum
0.540 0.460 0.000
C44 Other malignant neoplasms of skin
0.540 0.460 0.000
S80-S89 Injuries to the knee and lower leg
0.539 0.460 0.000
Z50 Care involving use of rehabilitation procedures
0.537 0.463 0.000
H25 Senile cataract
0.536 0.464 0.000
Z12 Special screening examination for neoplasms
0.536 0.464 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.535 0.465 0.000
D13.1 Stomach
0.534 0.466 0.000
D50-D53 Nutritional anaemias
0.534 0.466 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.531 0.469 0.000
K20 Oesophagitis
0.531 0.469 0.000
M80-M85 Disorders of bone density and structure
0.530 0.470 0.000
M75 Shoulder lesions
0.529 0.471 0.000
K50-K52 Noninfective enteritis and colitis
0.529 0.471 0.000
Chapter V Mental and behavioural disorders
0.526 0.473 0.000
M51 Other intervertebral disk disorders
0.526 0.474 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.526 0.474 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.526 0.474 0.000
Z96 Presence of other functional implants
0.524 0.476 0.000
K82 Other diseases of gallbladder
0.524 0.476 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.523 0.477 0.000
Z47 Other orthopaedic follow-up care
0.521 0.479 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.520 0.480 0.000
C66 Malignant neoplasm of ureter
0.520 0.480 0.000
C65 Malignant neoplasm of renal pelvis
0.520 0.480 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.520 0.480 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.519 0.481 0.000
N64 Other disorders of breast
0.519 0.481 0.000
N60 Benign mammary dysplasia
0.519 0.481 0.000
N61 Inflammatory disorders of breast
0.519 0.481 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.516 0.483 0.000
K25 Gastric ulcer
0.516 0.484 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.515 0.485 0.000
K81 Cholecystitis
0.515 0.485 0.000
K28 Gastrojejunal ulcer
0.515 0.485 0.000
K27 Peptic ulcer, site unspecified
0.515 0.485 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.515 0.485 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.515 0.485 0.000
K26 Duodenal ulcer
0.513 0.487 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.512 0.487 0.000
S50-S59 Injuries to the elbow and forearm
0.512 0.488 0.000
K29.6 Other gastritis
0.511 0.489 0.000
H33 Retinal detachments and breaks
0.510 0.490 0.000
Z46 Fitting and adjustment of other devices
0.508 0.492 0.000
N80.0 Endometriosis of uterus
0.507 0.493 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.505 0.495 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.505 0.495 0.000
N94.6 Dysmenorrhoea, unspecified
0.505 0.495 0.000
N94.5 Secondary dysmenorrhoea
0.505 0.495 0.000
N94.4 Primary dysmenorrhoea
0.505 0.495 0.000
N94.3 Premenstrual tension syndrome
0.505 0.495 0.000
N94.2 Vaginismus
0.505 0.495 0.000
N94.0 Mittelschmerz
0.505 0.495 0.000
D25 Leiomyoma of uterus
0.505 0.495 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.505 0.495 0.000
Z97 Presence of other devices
0.505 0.495 0.000
Z94 Transplanted organ and tissue status
0.505 0.495 0.000
Z93 Artificial opening status
0.505 0.495 0.000
Z89 Acquired absence of limb
0.505 0.495 0.000
Z84 Family history of other conditions
0.505 0.495 0.000
Z81 Family history of mental and behavioural disorders
0.505 0.495 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.505 0.495 0.000
K63.8 Other specified diseases of intestine
0.504 0.496 0.000
Z51.2 Other chemotherapy
0.503 0.497 0.000
Z54 Convalescence
0.502 0.497 0.000
Z52 Donors of organs and tissues
0.502 0.497 0.000
Z49 Care involving dialysis
0.502 0.497 0.000
Z48 Other surgical follow-up care
0.502 0.497 0.000
Z45 Adjustment and management of implanted device
0.502 0.497 0.000
Z44 Fitting and adjustment of external prosthetic device
0.502 0.497 0.000
Z43 Attention to artificial openings
0.502 0.497 0.000
Z41 Procedures for purposes other than remedying health state
0.502 0.497 0.000
Z40 Prophylactic surgery
0.502 0.497 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.502 0.498 0.000
K86 Other diseases of pancreas
0.502 0.498 0.000
K85 Acute pancreatitis
0.502 0.498 0.000
K83 Other diseases of biliary tract
0.502 0.498 0.000
K61.0 Anal abscess
0.502 0.498 0.000
K29.8 Duodenitis
0.502 0.498 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.499 0.501 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.499 0.501 0.000
N95.3 States associated with artificial menopause
0.499 0.501 0.000
N95.2 Postmenopausal atrophic vaginitis
0.499 0.501 0.000
N95.1 Menopausal and female climacteric states
0.499 0.501 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.499 0.501 0.000
N85.7 Haematometra
0.499 0.501 0.000
N85.6 Intra-uterine synechiae
0.499 0.501 0.000
N85.5 Inversion of uterus
0.499 0.501 0.000
N85.4 Malposition of uterus
0.499 0.501 0.000
N85.3 Subinvolution of uterus
0.499 0.501 0.000
N85.2 Hypertrophy of uterus
0.499 0.501 0.000
N85.1 Endometrial adenomatous hyperplasia
0.499 0.501 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.499 0.501 0.000
D80-D89 Certain disorders involving the immune mechanism
0.497 0.502 0.000
D55-D59 Haemolytic anaemias
0.497 0.502 0.000
K62.8 Other specified diseases of anus and rectum
0.497 0.503 0.000
M23 Internal derangement of knee
0.497 0.503 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.496 0.504 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.496 0.504 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.496 0.504 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.496 0.504 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.496 0.504 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.496 0.504 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.496 0.504 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.496 0.504 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.494 0.506 0.000
C79 Secondary malignant neoplasm of other sites
0.493 0.507 0.000
M24 Other specific joint derangements
0.492 0.508 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.491 0.509 0.000
H27 Other disorders of lens
0.491 0.509 0.000
C43 Malignant melanoma of skin
0.491 0.509 0.000
N13 Obstructive and reflux uropathy
0.491 0.509 0.000
D18.1 Lymphangioma, any site
0.490 0.510 0.000
Z51.8 Other specified medical care
0.490 0.510 0.000
M65 Synovitis and tenosynovitis
0.489 0.511 0.000
Z92 Personal history of medical treatment
0.489 0.511 0.000
K29.5 Chronic gastritis, unspecified
0.488 0.512 0.000
N35.8 Other urethral stricture
0.487 0.513 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.487 0.513 0.000
N35.0 Posttraumatic urethral stricture
0.487 0.513 0.000
Z87.0 Personal history of diseases of the respiratory system
0.487 0.513 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.486 0.514 0.000
K59.0 Constipation
0.486 0.514 0.000
K62.9 Disease of anus and rectum, unspecified
0.485 0.515 0.000
K62.7 Radiation proctitis
0.485 0.515 0.000
K62.6 Ulcer of anus and rectum
0.485 0.515 0.000
K62.4 Stenosis of anus and rectum
0.485 0.515 0.000
K62.3 Rectal prolapse
0.485 0.515 0.000
K62.2 Anal prolapse
0.485 0.515 0.000
K62.0 Anal polyp
0.485 0.515 0.000
K63.9 Disease of intestine, unspecified
0.485 0.515 0.000
K63.4 Enteroptosis
0.485 0.515 0.000
K63.3 Ulcer of intestine
0.485 0.515 0.000
K63.2 Fistula of intestine
0.485 0.515 0.000
K63.1 Perforation of intestine (nontraumatic)
0.485 0.515 0.000
K63.0 Abscess of intestine
0.485 0.515 0.000
J90-J94 Other diseases of pleura
0.484 0.515 0.000
C80 Malignant neoplasm without specification of site
0.484 0.516 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.484 0.516 0.000
Z95.1 Presence of aortocoronary bypass graft
0.484 0.516 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.483 0.517 0.000
O85-O92 Complications predominantly related to the puerperium
0.483 0.517 0.000
O80-O84 Delivery
0.483 0.517 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.483 0.517 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.483 0.517 0.000
O00-O08 Pregnancy with abortive outcome
0.483 0.517 0.000
D23.9 Skin, unspecified
0.482 0.517 0.000
D23.7 Skin of lower limb, including hip
0.482 0.517 0.000
D23.6 Skin of upper limb, including shoulder
0.482 0.517 0.000
D23.5 Skin of trunk
0.482 0.517 0.000
D23.4 Skin of scalp and neck
0.482 0.517 0.000
D23.3 Skin of other and unspecified parts of face
0.482 0.517 0.000
D23.2 Skin of ear and external auricular canal
0.482 0.517 0.000
D23.0 Skin of lip
0.482 0.517 0.000
H26.9 Cataract, unspecified
0.481 0.519 0.000
D60-D64 Aplastic and other anaemias
0.481 0.519 0.000
M47 Spondylosis
0.481 0.519 0.000
H90-H95 Other disorders of ear
0.479 0.520 0.000
D13.9 Ill-defined sites within the digestive system
0.479 0.521 0.000
D13.7 Endocrine pancreas
0.479 0.521 0.000
D13.6 Pancreas
0.479 0.521 0.000
D13.5 Extrahepatic bile ducts
0.479 0.521 0.000
D13.4 Liver
0.479 0.521 0.000
D13.3 Other and unspecified parts of small intestine
0.479 0.521 0.000
D13.2 Duodenum
0.479 0.521 0.000
D13.0 Oesophagus
0.479 0.521 0.000
H35 Other retinal disorders
0.479 0.521 0.000
O60-O75 Complications of labour and delivery
0.479 0.521 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.477 0.523 0.000
Z10 Routine general health check-up of defined subpopulation
0.477 0.523 0.000
Z04 Examination and observation for other reasons
0.477 0.523 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.477 0.523 0.000
Z85 Personal history of malignant neoplasm
0.477 0.523 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.477 0.523 0.000
T87 Complications peculiar to reattachment and amputation
0.477 0.523 0.000
T86 Failure and rejection of transplanted organs and tissues
0.477 0.523 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.477 0.523 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.477 0.523 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.477 0.523 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.477 0.523 0.000
M53 Other dorsopathies, not elsewhere classified
0.476 0.523 0.000
M50 Cervical disk disorders
0.476 0.523 0.000
H34 Retinal vascular occlusions
0.476 0.524 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.476 0.524 0.000
H31 Other disorders of choroid
0.476 0.524 0.000
H30 Chorioretinal inflammation
0.476 0.524 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.476 0.524 0.000
C34 Malignant neoplasm of bronchus and lung
0.474 0.525 0.000
K29.9 Gastroduodenitis, unspecified
0.474 0.526 0.000
K29.4 Chronic atrophic gastritis
0.474 0.526 0.000
K29.3 Chronic superficial gastritis
0.474 0.526 0.000
K29.2 Alcoholic gastritis
0.474 0.526 0.000
K29.1 Other acute gastritis
0.474 0.526 0.000
K29.0 Acute haemorrhagic gastritis
0.474 0.526 0.000
Z98.1 Arthrodesis status
0.474 0.526 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.474 0.526 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.473 0.527 0.000
N15 Other renal tubulo-interstitial diseases
0.473 0.527 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.473 0.527 0.000
N11 Chronic tubulo-interstitial nephritis
0.473 0.527 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.473 0.527 0.000
N10 Acute tubulo-interstitial nephritis
0.473 0.527 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.472 0.528 0.000
N80.9 Endometriosis, unspecified
0.472 0.528 0.000
N80.8 Other endometriosis
0.472 0.528 0.000
N80.6 Endometriosis in cutaneous scar
0.472 0.528 0.000
N80.5 Endometriosis of intestine
0.472 0.528 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.472 0.528 0.000
N80.3 Endometriosis of pelvic peritoneum
0.472 0.528 0.000
N80.2 Endometriosis of Fallopian tube
0.472 0.528 0.000
N80.1 Endometriosis of ovary
0.472 0.528 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.471 0.529 0.000
Z51.5 Palliative care
0.469 0.531 0.000
Z42 Follow-up care involving plastic surgery
0.469 0.531 0.000
H80-H83 Diseases of inner ear
0.469 0.531 0.000
H65-H75 Diseases of middle ear and mastoid
0.469 0.531 0.000
H60-H62 Diseases of external ear
0.469 0.531 0.000
M25 Other joint disorders, not elsewhere classified
0.468 0.532 0.000
N39 Other disorders of urinary system
0.467 0.532 0.000
Z51.0 Radiotherapy session
0.466 0.534 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.464 0.536 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.464 0.536 0.000
C32 Malignant neoplasm of larynx
0.464 0.536 0.000
C31 Malignant neoplasm of accessory sinuses
0.464 0.536 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.464 0.536 0.000
C37 Malignant neoplasm of thymus
0.464 0.536 0.000
C33 Malignant neoplasm of trachea
0.464 0.536 0.000
Z51.3 Blood transfusion without reported diagnosis
0.464 0.536 0.000
P90-P96 Other disorders originating in the perinatal period
0.461 0.538 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.461 0.538 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.461 0.538 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.461 0.538 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.461 0.538 0.000
P35-P39 Infections specific to the perinatal period
0.461 0.538 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.461 0.538 0.000
P10-P15 Birth trauma
0.461 0.538 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.461 0.538 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.461 0.538 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.461 0.538 0.000
Q80-Q89 Other congenital malformations
0.461 0.538 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.461 0.538 0.000
Q60-Q64 Congenital malformations of the urinary system
0.461 0.538 0.000
Q50-Q56 Congenital malformations of genital organs
0.461 0.538 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.461 0.538 0.000
Q35-Q37 Cleft lip and cleft palate
0.461 0.538 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.461 0.538 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.461 0.538 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.461 0.538 0.000
Q00-Q07 Congenital malformations of the nervous system
0.461 0.538 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.461 0.538 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.461 0.538 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.461 0.539 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.461 0.539 0.000
N06 Isolated proteinuria with specified morphological lesion
0.461 0.539 0.000
N05 Unspecified nephritic syndrome
0.461 0.539 0.000
N04 Nephrotic syndrome
0.461 0.539 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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