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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16850864
log Bayes Factor = 1.15468
Chromosome 4   position 75,160,824  (GRCh37) Explore rs16850864 on Ensembl!
Variant rs16850864 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIV Diseases of the genitourinary system
0.922 0.078 0.000
N32.0 Bladder-neck obstruction
0.921 0.079 0.000
N32 Other disorders of bladder
0.921 0.079 0.000
N30-N39 Other diseases of urinary system
0.919 0.081 0.000
# Top node
0.918 0.082 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.913 0.087 0.000
E10-E14 Diabetes mellitus
0.907 0.093 0.000
Chapter X Diseases of the respiratory system
0.905 0.095 0.000
E10 Insulin-dependent diabetes mellitus
0.890 0.110 0.000
N10-N16 Renal tubulo-interstitial diseases
0.876 0.124 0.000
Chapter II Neoplasms
0.876 0.124 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.855 0.145 0.000
J09-J18 Influenza and pneumonia
0.850 0.150 0.000
Chapter VII Diseases of the eye and adnexa
0.841 0.159 0.000
N17-N19 Renal failure
0.833 0.167 0.000
E11 Non-insulin-dependent diabetes mellitus
0.830 0.170 0.000
E10.9 Without complications
0.827 0.173 0.000
N32.3 Diverticulum of bladder
0.825 0.175 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.813 0.187 0.000
N13 Obstructive and reflux uropathy
0.801 0.199 0.000
J18 Pneumonia, organism unspecified
0.797 0.203 0.000
E10.3 With ophthalmic complications
0.797 0.203 0.000
D00-D09 In situ neoplasms
0.793 0.207 0.000
Chapter I Certain infectious and parasitic diseases
0.788 0.212 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.785 0.215 0.000
J40-J47 Chronic lower respiratory diseases
0.784 0.216 0.000
N60-N64 Disorders of breast
0.777 0.223 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.775 0.225 0.000
J00-J06 Acute upper respiratory infections
0.761 0.239 0.000
E00-E07 Disorders of thyroid gland
0.755 0.245 0.000
O60-O75 Complications of labour and delivery
0.751 0.249 0.000
N32.8 Other specified disorders of bladder
0.736 0.264 0.000
N18 Chronic renal failure
0.732 0.268 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.731 0.269 0.000
E20-E35 Disorders of other endocrine glands
0.729 0.271 0.000
N13.3 Other and unspecified hydronephrosis
0.727 0.273 0.000
H43-H45 Disorders of vitreous body and globe
0.723 0.277 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.722 0.278 0.000
E10.1 With ketoacidosis
0.720 0.280 0.000
J95-J99 Other diseases of the respiratory system
0.719 0.281 0.000
C91 Lymphoid leukaemia
0.716 0.284 0.000
C50-C50 Malignant neoplasm of breast
0.715 0.285 0.000
J18.9 Pneumonia, unspecified
0.714 0.286 0.000
B25-B34 Other viral diseases
0.713 0.287 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.705 0.295 0.000
H25-H28 Disorders of lens
0.703 0.297 0.000
E40-E46 Malnutrition
0.702 0.298 0.000
N99-N99 Other disorders of the genitourinary system
0.698 0.302 0.000
E50-E64 Other nutritional deficiencies
0.696 0.304 0.000
Chapter XXII Codes for special purposes
0.696 0.304 0.000
E14 Unspecified diabetes mellitus
0.696 0.304 0.000
J44 Other chronic obstructive pulmonary disease
0.694 0.306 0.000
E10.4 With neurological complications
0.691 0.308 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.691 0.309 0.000
N10 Acute tubulo-interstitial nephritis
0.691 0.309 0.000
C92 Myeloid leukaemia
0.690 0.310 0.000
E11.3 With ophthalmic complications
0.687 0.313 0.000
H40-H42 Glaucoma
0.687 0.313 0.000
N40-N51 Diseases of male genital organs
0.685 0.315 0.000
E11.9 Without complications
0.685 0.315 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.684 0.315 0.000
A30-A49 Other bacterial diseases
0.678 0.322 0.000
Chapter VIII Diseases of the ear and mastoid process
0.678 0.322 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.676 0.324 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.675 0.325 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.675 0.325 0.000
C85.1 B-cell lymphoma, unspecified
0.672 0.328 0.000
J84 Other interstitial pulmonary diseases
0.672 0.328 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.672 0.328 0.000
N35 Urethral stricture
0.670 0.330 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.669 0.331 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.669 0.331 0.000
J18.1 Lobar pneumonia, unspecified
0.666 0.334 0.000
D03 Melanoma in situ
0.664 0.336 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.664 0.336 0.000
N32.4 Rupture of bladder, nontraumatic
0.660 0.340 0.000
N32.2 Vesical fistula, not elsewhere classified
0.660 0.340 0.000
N32.1 Vesicointestinal fistula
0.660 0.340 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.660 0.340 0.000
B34 Viral infection of unspecified site
0.660 0.340 0.000
N37 Urethral disorders in diseases classified elsewhere
0.659 0.341 0.000
N36 Other disorders of urethra
0.659 0.341 0.000
N34 Urethritis and urethral syndrome
0.659 0.341 0.000
N33 Bladder disorders in diseases classified elsewhere
0.659 0.341 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.658 0.342 0.000
N17 Acute renal failure
0.655 0.345 0.000
H10-H13 Disorders of conjunctiva
0.654 0.346 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.654 0.346 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.654 0.346 0.000
E65-E68 Obesity and other hyperalimentation
0.652 0.348 0.000
N25-N29 Other disorders of kidney and ureter
0.651 0.348 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.651 0.349 0.000
E13 Other specified diabetes mellitus
0.651 0.349 0.000
E12 Malnutrition-related diabetes mellitus
0.651 0.349 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.649 0.351 0.000
O63 Long labour
0.647 0.353 0.000
E11.2 With renal complications
0.647 0.353 0.000
C81 Hodgkin's disease
0.644 0.356 0.000
H55-H59 Other disorders of eye and adnexa
0.644 0.356 0.000
E11.4 With neurological complications
0.642 0.358 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.640 0.360 0.000
E10.8 With unspecified complications
0.638 0.362 0.000
E10.7 With multiple complications
0.638 0.362 0.000
E10.6 With other specified complications
0.638 0.362 0.000
E10.5 With peripheral circulatory complications
0.638 0.362 0.000
E10.2 With renal complications
0.638 0.362 0.000
E10.0 With coma
0.638 0.362 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.638 0.362 0.000
H25 Senile cataract
0.637 0.363 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.635 0.365 0.000
O70 Perineal laceration during delivery
0.635 0.365 0.000
N19 Unspecified renal failure
0.633 0.367 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.632 0.368 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.628 0.372 0.000
N15 Other renal tubulo-interstitial diseases
0.628 0.372 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.628 0.372 0.000
N11 Chronic tubulo-interstitial nephritis
0.628 0.372 0.000
J90-J94 Other diseases of pleura
0.628 0.372 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.628 0.372 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.628 0.372 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.628 0.372 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.628 0.372 0.000
N48 Other disorders of penis
0.628 0.372 0.000
H43 Disorders of vitreous body
0.623 0.377 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.623 0.377 0.000
B34.9 Viral infection, unspecified
0.621 0.379 0.000
D09 Carcinoma in situ of other and unspecified sites
0.621 0.379 0.000
N63 Unspecified lump in breast
0.621 0.379 0.000
J18.0 Bronchopneumonia, unspecified
0.617 0.383 0.000
J20-J22 Other acute lower respiratory infections
0.617 0.383 0.000
C91.1 Chronic lymphocytic leukaemia
0.617 0.383 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.615 0.385 0.000
N18.4 Chronic kidney disease, stage 4
0.614 0.386 0.000
J03 Acute tonsillitis
0.614 0.386 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.613 0.387 0.000
C95 Leukaemia of unspecified cell type
0.613 0.387 0.000
C94 Other leukaemias of specified cell type
0.613 0.387 0.000
C93 Monocytic leukaemia
0.613 0.387 0.000
C88 Malignant immunoproliferative diseases
0.613 0.387 0.000
C86 Other specified types of T/NK-cell lymphoma
0.613 0.387 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.613 0.387 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.613 0.387 0.000
J43 Emphysema
0.612 0.388 0.000
N20-N23 Urolithiasis
0.612 0.388 0.000
J60-J70 Lung diseases due to external agents
0.611 0.389 0.000
J17 Pneumonia in diseases classified elsewhere
0.610 0.390 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.610 0.390 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.610 0.390 0.000
J12 Viral pneumonia, not elsewhere classified
0.610 0.390 0.000
J11 Influenza, virus not identified
0.610 0.390 0.000
J10 Influenza due to identified influenza virus
0.610 0.390 0.000
J14 Pneumonia due to Haemophilus influenzae
0.610 0.390 0.000
J09 Influenza due to certain identified influenza virus
0.610 0.390 0.000
C64-C68 Malignant neoplasms of urinary tract
0.609 0.391 0.000
J40 Bronchitis, not specified as acute or chronic
0.608 0.392 0.000
J80 Adult respiratory distress syndrome
0.606 0.393 0.000
J42 Unspecified chronic bronchitis
0.606 0.394 0.000
A41 Other septicaemia
0.604 0.396 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.603 0.397 0.000
N61 Inflammatory disorders of breast
0.601 0.399 0.000
C50 Malignant neoplasm of breast
0.600 0.400 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.598 0.402 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.598 0.402 0.000
B35-B49 Mycoses
0.596 0.404 0.000
H25.0 Senile incipient cataract
0.596 0.404 0.000
E11.8 With unspecified complications
0.595 0.405 0.000
E11.7 With multiple complications
0.595 0.405 0.000
E11.6 With other specified complications
0.595 0.405 0.000
E11.5 With peripheral circulatory complications
0.595 0.405 0.000
E11.1 With ketoacidosis
0.595 0.405 0.000
E11.0 With coma
0.595 0.405 0.000
N00-N08 Glomerular diseases
0.595 0.405 0.000
E27 Other disorders of adrenal gland
0.593 0.407 0.000
D05 Carcinoma in situ of breast
0.592 0.408 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.592 0.408 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.591 0.408 0.000
E05.9 Thyrotoxicosis, unspecified
0.589 0.411 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.588 0.412 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.587 0.413 0.000
N30 Cystitis
0.587 0.413 0.000
J02 Acute pharyngitis
0.586 0.414 0.000
Chapter XX External causes of morbidity and mortality
0.586 0.414 0.000
J46 Status asthmaticus
0.586 0.414 0.000
O66 Other obstructed labour
0.585 0.415 0.000
O85-O92 Complications predominantly related to the puerperium
0.583 0.417 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.582 0.418 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.581 0.419 0.000
O62 Abnormalities of forces of labour
0.581 0.419 0.000
N62 Hypertrophy of breast
0.580 0.420 0.000
D06 Carcinoma in situ of cervix uteri
0.578 0.422 0.000
E06 Thyroiditis
0.576 0.423 0.000
H40 Glaucoma
0.576 0.424 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.574 0.426 0.000
N13.8 Other obstructive and reflux uropathy
0.574 0.426 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.574 0.426 0.000
N13.6 Pyonephrosis
0.574 0.426 0.000
N13.4 Hydroureter
0.574 0.426 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.574 0.426 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.574 0.426 0.000
C92.1 Chronic myeloid leukaemia
0.574 0.426 0.000
H30-H36 Disorders of choroid and retina
0.574 0.426 0.000
H53-H54 Visual disturbances and blindness
0.573 0.427 0.000
E04 Other non-toxic goitre
0.573 0.427 0.000
J18.8 Other pneumonia, organism unspecified
0.571 0.429 0.000
J18.2 Hypostatic pneumonia, unspecified
0.571 0.429 0.000
N18.9 Chronic renal failure, unspecified
0.570 0.430 0.000
H80-H83 Diseases of inner ear
0.570 0.430 0.000
J30-J39 Other diseases of upper respiratory tract
0.569 0.431 0.000
C51-C58 Malignant neoplasms of female genital organs
0.569 0.431 0.000
D04 Carcinoma in situ of skin
0.568 0.431 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.568 0.431 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.568 0.431 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.568 0.431 0.000
N64 Other disorders of breast
0.566 0.434 0.000
B99-B99 Other infectious diseases
0.565 0.435 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.565 0.435 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.565 0.435 0.000
B65-B83 Helminthiases
0.565 0.435 0.000
B50-B64 Protozoal diseases
0.565 0.435 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.565 0.435 0.000
B15-B19 Viral hepatitis
0.565 0.435 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.565 0.435 0.000
A80-A89 Viral infections of the central nervous system
0.565 0.435 0.000
A75-A79 Rickettsioses
0.565 0.435 0.000
A70-A74 Other diseases caused by chlamydiae
0.565 0.435 0.000
A65-A69 Other spirochaetal diseases
0.565 0.435 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.565 0.435 0.000
A20-A28 Certain zoonotic bacterial diseases
0.565 0.435 0.000
A15-A19 Tuberculosis
0.565 0.435 0.000
N60 Benign mammary dysplasia
0.564 0.436 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.564 0.436 0.000
N18.3 Chronic kidney disease, stage 3
0.563 0.437 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.562 0.437 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.562 0.437 0.000
C85.0 Lymphosarcoma
0.562 0.437 0.000
J41 Simple and mucopurulent chronic bronchitis
0.562 0.438 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.561 0.439 0.000
J00 Acute nasopharyngitis [common cold]
0.559 0.440 0.000
C44 Other malignant neoplasms of skin
0.559 0.441 0.000
Chapter V Mental and behavioural disorders
0.558 0.442 0.000
O63.1 Prolonged second stage (of labour)
0.557 0.443 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.556 0.444 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.552 0.448 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.551 0.449 0.000
E46 Unspecified protein-energy malnutrition
0.550 0.450 0.000
E53 Deficiency of other B group vitamins
0.550 0.450 0.000
C50.4 Upper-outer quadrant of breast
0.549 0.451 0.000
J47 Bronchiectasis
0.548 0.452 0.000
H44 Disorders of globe
0.547 0.452 0.000
O20 Haemorrhage in early pregnancy
0.546 0.454 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.545 0.454 0.000
J04 Acute laryngitis and tracheitis
0.545 0.454 0.000
J01 Acute sinusitis
0.545 0.454 0.000
E14.9 Without complications
0.544 0.456 0.000
C60-C63 Malignant neoplasms of male genital organs
0.544 0.456 0.000
C78.7 Secondary malignant neoplasm of liver
0.544 0.456 0.000
C83.0 Small cell (diffuse)
0.542 0.458 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.542 0.458 0.000
E07 Other disorders of thyroid
0.542 0.458 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.542 0.458 0.000
E00 Congenital iodine-deficiency syndrome
0.542 0.458 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.542 0.458 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.538 0.461 0.000
O74 Complications of anaesthesia during labour and delivery
0.538 0.461 0.000
O73 Retained placenta and membranes, without haemorrhage
0.538 0.461 0.000
O71 Other obstetric trauma
0.538 0.461 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.538 0.461 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.538 0.461 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.538 0.461 0.000
O61 Failed induction of labour
0.538 0.461 0.000
O60 Preterm delivery
0.538 0.461 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.538 0.462 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.537 0.462 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.537 0.463 0.000
N42 Other disorders of prostate
0.536 0.463 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.536 0.464 0.000
N18.5 Chronic kidney disease, stage 5
0.536 0.464 0.000
N48.1 Balanoposthitis
0.536 0.464 0.000
C44.3 Skin of other and unspecified parts of face
0.533 0.467 0.000
E16 Other disorders of pancreatic internal secretion
0.532 0.468 0.000
C09 Malignant neoplasm of tonsil
0.531 0.469 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.530 0.470 0.000
O70.1 Second degree perineal laceration during delivery
0.527 0.473 0.000
N17.9 Acute renal failure, unspecified
0.527 0.473 0.000
H43.1 Vitreous haemorrhage
0.526 0.474 0.000
N45 Orchitis and epididymitis
0.526 0.474 0.000
N41 Inflammatory diseases of prostate
0.525 0.475 0.000
N18.8 Other chronic renal failure
0.525 0.475 0.000
N18.2 Chronic kidney disease, stage 2
0.525 0.475 0.000
N18.1 Chronic kidney disease, stage 1
0.525 0.475 0.000
N18.0 End-stage renal disease
0.525 0.475 0.000
O24 Diabetes mellitus in pregnancy
0.524 0.475 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.524 0.476 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.523 0.477 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.523 0.477 0.000
D03.5 Melanoma in situ of trunk
0.523 0.477 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.523 0.477 0.000
E34 Other endocrine disorders
0.523 0.477 0.000
E32 Diseases of thymus
0.523 0.477 0.000
E31 Polyglandular dysfunction
0.523 0.477 0.000
E30 Disorders of puberty, not elsewhere classified
0.523 0.477 0.000
E29 Testicular dysfunction
0.523 0.477 0.000
E28 Ovarian dysfunction
0.523 0.477 0.000
E26 Hyperaldosteronism
0.523 0.477 0.000
E25 Adrenogenital disorders
0.523 0.477 0.000
E24 Cushing's syndrome
0.523 0.477 0.000
E23 Hypofunction and other disorders of pituitary gland
0.523 0.477 0.000
E22 Hyperfunction of pituitary gland
0.523 0.477 0.000
E20 Hypoparathyroidism
0.523 0.477 0.000
N48.8 Other specified disorders of penis
0.523 0.477 0.000
D07.5 Prostate
0.522 0.478 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.520 0.480 0.000
J81 Pulmonary oedema
0.520 0.480 0.000
O70.9 Perineal laceration during delivery, unspecified
0.520 0.480 0.000
H20 Iridocyclitis
0.519 0.480 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.518 0.482 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.518 0.482 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.518 0.482 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.518 0.482 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.517 0.483 0.000
O00-O08 Pregnancy with abortive outcome
0.516 0.483 0.000
J96 Respiratory failure, not elsewhere classified
0.515 0.485 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.515 0.485 0.000
C91.9 Lymphoid leukaemia, unspecified
0.513 0.486 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.513 0.486 0.000
C91.7 Other lymphoid leukaemia
0.513 0.486 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.513 0.486 0.000
C91.5 Adult T-cell leukaemia
0.513 0.486 0.000
C91.4 Hairy-cell leukaemia
0.513 0.486 0.000
C91.3 Prolymphocytic leukaemia
0.513 0.486 0.000
C91.2 Subacute lymphocytic leukaemia
0.513 0.486 0.000
C91.0 Acute lymphoblastic leukaemia
0.513 0.486 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.512 0.487 0.000
H10 Conjunctivitis
0.512 0.487 0.000
J98 Other respiratory disorders
0.512 0.488 0.000
B33 Other viral diseases, not elsewhere classified
0.511 0.489 0.000
B30 Viral conjunctivitis
0.511 0.489 0.000
B27 Infectious mononucleosis
0.511 0.489 0.000
B26 Mumps
0.511 0.489 0.000
B25 Cytomegaloviral disease
0.511 0.489 0.000
C90.0 Multiple myeloma
0.509 0.491 0.000
J03.9 Acute tonsillitis, unspecified
0.509 0.491 0.000
N48.4 Impotence of organic origin
0.508 0.492 0.000
J91 Pleural effusion in conditions classified elsewhere
0.508 0.492 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.507 0.493 0.000
C73 Malignant neoplasm of thyroid gland
0.506 0.494 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.505 0.494 0.000
Q80-Q89 Other congenital malformations
0.505 0.494 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.505 0.494 0.000
Q60-Q64 Congenital malformations of the urinary system
0.505 0.494 0.000
Q50-Q56 Congenital malformations of genital organs
0.505 0.494 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.505 0.494 0.000
Q35-Q37 Cleft lip and cleft palate
0.505 0.494 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.505 0.494 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.505 0.494 0.000
Q00-Q07 Congenital malformations of the nervous system
0.505 0.494 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.504 0.496 0.000
H27 Other disorders of lens
0.504 0.496 0.000
Chapter VI Diseases of the nervous system
0.504 0.496 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.503 0.497 0.000
E45 Retarded development following protein-energy malnutrition
0.503 0.497 0.000
E43 Unspecified severe protein-energy malnutrition
0.503 0.497 0.000
E42 Marasmic kwashiorkor
0.503 0.497 0.000
E41 Nutritional marasmus
0.503 0.497 0.000
E40 Kwashiorkor
0.503 0.497 0.000
H57 Other disorders of eye and adnexa
0.502 0.497 0.000
O80-O84 Delivery
0.500 0.499 0.001
E64 Sequelae of malnutrition and other nutritional deficiencies
0.499 0.501 0.000
E63 Other nutritional deficiencies
0.499 0.501 0.000
E61 Deficiency of other nutrient elements
0.499 0.501 0.000
E56 Other vitamin deficiencies
0.499 0.501 0.000
E51 Thiamine deficiency
0.499 0.501 0.000
E50 Vitamin A deficiency
0.499 0.501 0.000
E60 Dietary zinc deficiency
0.499 0.501 0.000
E59 Dietary selenium deficiency
0.499 0.501 0.000
E58 Dietary calcium deficiency
0.499 0.501 0.000
E54 Ascorbic acid deficiency
0.499 0.501 0.000
E52 Niacin deficiency [pellagra]
0.499 0.501 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.499 0.501 0.000
E14.8 With unspecified complications
0.499 0.501 0.000
E14.7 With multiple complications
0.499 0.501 0.000
E14.6 With other specified complications
0.499 0.501 0.000
E14.5 With peripheral circulatory complications
0.499 0.501 0.000
E14.4 With neurological complications
0.499 0.501 0.000
E14.3 With ophthalmic complications
0.499 0.501 0.000
E14.2 Withrenal complications
0.499 0.501 0.000
E14.1 With ketoacidosis
0.499 0.501 0.000
E14.0 With coma
0.499 0.501 0.000
D09.0 Bladder
0.497 0.503 0.000
O63.0 Prolonged first stage (of labour)
0.497 0.503 0.000
E15 Nondiabetic hypoglycaemic coma
0.495 0.504 0.000
N76 Other inflammation of vagina and vulva
0.495 0.505 0.000
C92.9 Myeloid leukaemia, unspecified
0.495 0.505 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.495 0.505 0.000
C92.7 Other myeloid leukaemia
0.495 0.505 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.495 0.505 0.000
C92.5 Acute myelomonocytic leukaemia
0.495 0.505 0.000
C92.4 Acute promyelocytic leukaemia
0.495 0.505 0.000
C92.3 Myeloid sarcoma
0.495 0.505 0.000
C92.2 Subacute myeloid leukaemia
0.495 0.505 0.000
C81.9 Hodgkin's disease, unspecified
0.493 0.507 0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.493 0.507 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.492 0.507 0.000
H42 Glaucoma in diseases classified elsewhere
0.492 0.508 0.000
O72 Postpartum haemorrhage
0.492 0.508 0.000
C83.3 Large cell (diffuse)
0.492 0.508 0.000
N35.9 Urethral stricture, unspecified
0.492 0.508 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.491 0.509 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.491 0.509 0.000
N46 Male infertility
0.491 0.509 0.000
N44 Torsion of testis
0.491 0.509 0.000
C92.0 Acute myeloid leukaemia
0.491 0.509 0.000
J43.9 Emphysema, unspecified
0.490 0.510 0.000
H43.3 Other vitreous opacities
0.489 0.511 0.000
E55 Vitamin D deficiency
0.487 0.513 0.000
A48 Other bacterial diseases, not elsewhere classified
0.486 0.514 0.000
A44 Bartonellosis
0.486 0.514 0.000
A43 Nocardiosis
0.486 0.514 0.000
A42 Actinomycosis
0.486 0.514 0.000
A40 Streptococcal septicaemia
0.486 0.514 0.000
A39 Meningococcal infection
0.486 0.514 0.000
A37 Whooping cough
0.486 0.514 0.000
A36 Diphtheria
0.486 0.514 0.000
A32 Listeriosis
0.486 0.514 0.000
A31 Infection due to other mycobacteria
0.486 0.514 0.000
A30 Leprosy [Hansen's disease]
0.486 0.514 0.000
A46 Erysipelas
0.486 0.514 0.000
A38 Scarlet fever
0.486 0.514 0.000
A35 Other tetanus
0.486 0.514 0.000
A34 Obstetrical tetanus
0.486 0.514 0.000
A33 Tetanus neonatorum
0.486 0.514 0.000
H25.1 Senile nuclear cataract
0.486 0.514 0.000
N72 Inflammatory disease of cervix uteri
0.486 0.514 0.000
N43 Hydrocele and spermatocele
0.486 0.514 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.485 0.515 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.485 0.515 0.000
C83.7 Burkitt's tumour
0.485 0.515 0.000
C83.6 Undifferentiated (diffuse)
0.485 0.515 0.000
C83.5 Lymphoblastic (diffuse)
0.485 0.515 0.000
C83.4 Immunoblastic (diffuse)
0.485 0.515 0.000
C83.2 Mixed small and large cell (diffuse)
0.485 0.515 0.000
C83.1 Small cleaved cell (diffuse)
0.485 0.515 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.484 0.516 0.000
C13 Malignant neoplasm of hypopharynx
0.484 0.516 0.000
C11 Malignant neoplasm of nasopharynx
0.484 0.516 0.000
C10 Malignant neoplasm of oropharynx
0.484 0.516 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.484 0.516 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.484 0.516 0.000
C05 Malignant neoplasm of palate
0.484 0.516 0.000
C04 Malignant neoplasm of floor of mouth
0.484 0.516 0.000
C03 Malignant neoplasm of gum
0.484 0.516 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.484 0.516 0.000
C00 Malignant neoplasm of lip
0.484 0.516 0.000
C12 Malignant neoplasm of pyriform sinus
0.484 0.516 0.000
C07 Malignant neoplasm of parotid gland
0.484 0.516 0.000
C01 Malignant neoplasm of base of tongue
0.484 0.516 0.000
H36 Retinal disorders in diseases classified elsewhere
0.483 0.516 0.000
B95-B98 Bacterial, viral and other infectious agents
0.483 0.517 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.482 0.518 0.000
J84.8 Other specified interstitial pulmonary diseases
0.482 0.518 0.000
J84.0 Alveolar and parietoalveolar conditions
0.482 0.518 0.000
N75 Diseases of Bartholin's gland
0.482 0.518 0.000
J92 Pleural plaque
0.481 0.518 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.481 0.519 0.000
N35.8 Other urethral stricture
0.481 0.519 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.481 0.519 0.000
N35.0 Posttraumatic urethral stricture
0.481 0.519 0.000
N23 Unspecified renal colic
0.480 0.520 0.000
E05.8 Other thyrotoxicosis
0.480 0.520 0.000
E05.5 Thyroid crisis or storm
0.480 0.520 0.000
E05.4 Thyrotoxicosis factitia
0.480 0.520 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.480 0.520 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.480 0.520 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.480 0.520 0.000
O29 Complications of anaesthesia during pregnancy
0.480 0.520 0.000
O28 Abnormal findings on antenatal screening of mother
0.480 0.520 0.000
O23 Infections of genito-urinary tract in pregnancy
0.480 0.520 0.000
O22 Venous complications in pregnancy
0.480 0.520 0.000
O21 Excessive vomiting in pregnancy
0.480 0.520 0.000
O25 Malnutrition in pregnancy
0.480 0.520 0.000
H11 Other disorders of conjunctiva
0.479 0.521 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.478 0.522 0.000
H60-H62 Diseases of external ear
0.477 0.523 0.000
D03.9 Melanoma in situ, unspecified
0.476 0.523 0.000
D03.8 Melanoma in situ of other sites
0.476 0.523 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.476 0.523 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.476 0.523 0.000
D03.4 Melanoma in situ of scalp and neck
0.476 0.523 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.476 0.523 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.476 0.523 0.000
D03.0 Melanoma in situ of lip
0.476 0.523 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.476 0.524 0.000
N71 Inflammatory disease of uterus, except cervix
0.476 0.524 0.000
N70 Salpingitis and oophoritis
0.476 0.524 0.000
A49 Bacterial infection of unspecified site
0.475 0.525 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.473 0.526 0.000
C74 Malignant neoplasm of adrenal gland
0.473 0.526 0.000
B34.8 Other viral infections of unspecified site
0.473 0.527 0.000
B34.4 Papovirus infection, unspecified
0.473 0.527 0.000
B34.3 Parvovirus infection, unspecified
0.473 0.527 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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