TreeWAS – Variant ID: rs16856202

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter VIII Diseases of the ear and mastoid process	0.999	0.001
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.999	0.001
R50-R69 General symptoms and signs	0.998	0.002
Chapter II Neoplasms	0.990	0.010
R30-R39 Symptoms and signs involving the urinary system	0.986	0.014
R35 Polyuria	0.985	0.015
D00-D09 In situ neoplasms	0.984	0.016
H65-H75 Diseases of middle ear and mastoid	0.984	0.016
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.979	0.021
Chapter XIV Diseases of the genitourinary system	0.975	0.025
H90-H95 Other disorders of ear	0.974	0.026
D05 Carcinoma in situ of breast	0.968	0.032
R63 Symptoms and signs concerning food and fluid intake	0.964	0.036
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.963	0.037
R52 Pain, not elsewhere classified	0.962	0.038
Chapter XV Pregnancy, childbirth and the puerperium	0.960	0.040
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.960	0.040
D05.1 Intraductal carcinoma in situ	0.959	0.041
Chapter I Certain infectious and parasitic diseases	0.956	0.044
R68 Other general symptoms and signs	0.949	0.051
H91 Other hearing loss	0.947	0.053
H65 Nonsuppurative otitis media	0.947	0.053
N25-N29 Other disorders of kidney and ureter	0.947	0.053
C34 Malignant neoplasm of bronchus and lung	0.942	0.058
H91.9 Hearing loss, unspecified	0.928	0.072
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.925	0.075
H80-H83 Diseases of inner ear	0.925	0.075
R63.0 Anorexia	0.924	0.076
H66 Suppurative and unspecified otitis media	0.922	0.078
O00-O08 Pregnancy with abortive outcome	0.922	0.078
Chapter V Mental and behavioural disorders	0.920	0.080
N28 Other disorders of kidney and ureter, not elsewhere classified	0.918	0.082
R68.8 Other specified general symptoms and signs	0.909	0.091
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.909	0.091
R23 Other skin changes	0.903	0.097
N80-N98 Noninflammatory disorders of female genital tract	0.903	0.097
C34.9 Bronchus or lung, unspecified	0.901	0.099
N28.8 Other specified disorders of kidney and ureter	0.895	0.105
R57 Shock, not elsewhere classified	0.893	0.107
N84 Polyp of female genital tract	0.892	0.108
A00-A09 Intestinal infectious diseases	0.891	0.109
O20-O29 Other maternal disorders predominantly related to pregnancy	0.889	0.111
N84.0 Polyp of corpus uteri	0.888	0.112
H65.3 Chronic mucoid otitis media	0.887	0.113
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.887	0.113
C50-C50 Malignant neoplasm of breast	0.886	0.114
R21 Rash and other nonspecific skin eruption	0.882	0.118
D37-D48 Neoplasms of uncertain or unknown behaviour	0.882	0.118
H81 Disorders of vestibular function	0.879	0.121
O03 Spontaneous abortion	0.876	0.124
H66.9 Otitis media, unspecified	0.873	0.127
N70-N77 Inflammatory diseases of female pelvic organs	0.873	0.127
R55 Syncope and collapse	0.873	0.127
T66-T78 Other and unspecified effects of external causes	0.872	0.128
S40-S49 Injuries to the shoulder and upper arm	0.870	0.130
R52.2 Other chronic pain	0.865	0.135
T36-T50 Poisoning by drugs, medicaments and biological substances	0.863	0.137
R30 Pain associated with micturition	0.862	0.138
C34.1 Upper lobe, bronchus or lung	0.862	0.138
Chapter IV Endocrine, nutritional and metabolic diseases	0.854	0.146
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.853	0.147
D60-D64 Aplastic and other anaemias	0.848	0.152
R50 Fever of unknown origin	0.844	0.156
B95-B98 Bacterial, viral and other infectious agents	0.844	0.156
C83 Diffuse non-Hodgkin's lymphoma	0.834	0.166
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.834	0.166
O04 Medical abortion	0.828	0.172
N92 Excessive, frequent and irregular menstruation	0.827	0.173
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.825	0.175
C92 Myeloid leukaemia	0.824	0.176
R52.1 Chronic intractable pain	0.823	0.177
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.822	0.178
N95 Menopausal and other perimenopausal disorders	0.821	0.179
H81.0 Meniere's disease	0.820	0.180
R59 Enlarged lymph nodes	0.820	0.180
R52.9 Pain, unspecified	0.819	0.181
N92.1 Excessive and frequent menstruation with irregular cycle	0.818	0.182
M45-M49 Spondylopathies	0.818	0.182
O03.9 Complete or unspecified, without complication	0.814	0.186
R63.8 Other symptoms and signs concerning food and fluid intake	0.813	0.187
C50 Malignant neoplasm of breast	0.812	0.188
S20-S29 Injuries to the thorax	0.811	0.189
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.808	0.192
O20 Haemorrhage in early pregnancy	0.807	0.193
H65.2 Chronic serous otitis media	0.807	0.193
R64 Cachexia	0.806	0.194
A09.9 Gastroenteritis and colitis of unspecified origin	0.804	0.196
S90-S99 Injuries to the ankle and foot	0.802	0.198
N73 Other female pelvic inflammatory diseases	0.802	0.198
D06 Carcinoma in situ of cervix uteri	0.801	0.199
H90 Conductive and sensorineural hearing loss	0.799	0.200
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.799	0.201
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.796	0.204
N17-N19 Renal failure	0.794	0.206
N00-N08 Glomerular diseases	0.793	0.207
A30-A49 Other bacterial diseases	0.792	0.208
H74 Other disorders of middle ear and mastoid	0.789	0.211
D09 Carcinoma in situ of other and unspecified sites	0.784	0.216
R23.8 Other and unspecified skin changes	0.784	0.216
R50.9 Fever, unspecified	0.783	0.217
D07 Carcinoma in situ of other and unspecified genital organs	0.779	0.221
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.779	0.221
H73 Other disorders of tympanic membrane	0.779	0.221
R57.2 Septic shock	0.777	0.223
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.775	0.225
S10-S19 Injuries to the neck	0.773	0.227
R23.4 Changes in skin texture	0.772	0.228
N73.6 Female pelvic peritoneal adhesions	0.771	0.229
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.771	0.229
Chapter IX Diseases of the circulatory system	0.770	0.230
N80 Endometriosis	0.770	0.230
N99-N99 Other disorders of the genitourinary system	0.769	0.231
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.766	0.234
D64 Other anaemias	0.763	0.237
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.762	0.238
N26 Unspecified contracted kidney	0.761	0.239
T78 Adverse effects, not elsewhere classified	0.759	0.241
F30-F39 Mood [affective] disorders	0.759	0.241
I05-I09 Chronic rheumatic heart diseases	0.759	0.241
F80-F89 Disorders of psychological development	0.758	0.242
R56 Convulsions, not elsewhere classified	0.757	0.243
R59.0 Localised enlarged lymph nodes	0.757	0.243
O80-O84 Delivery	0.755	0.245
C83.3 Large cell (diffuse)	0.754	0.246
S50-S59 Injuries to the elbow and forearm	0.753	0.247
F10 Mental and behavioural disorders due to use of alcohol	0.751	0.249
D05.0 Lobular carcinoma in situ	0.750	0.249
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.750	0.250
O03.4 Incomplete, without complication	0.747	0.253
E20-E35 Disorders of other endocrine glands	0.746	0.254
E50-E64 Other nutritional deficiencies	0.742	0.258
D03 Melanoma in situ	0.741	0.259
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.741	0.259
N10-N16 Renal tubulo-interstitial diseases	0.740	0.260
S80-S89 Injuries to the knee and lower leg	0.740	0.260
O04.9 Complete or unspecified, without complication	0.738	0.262
H60-H62 Diseases of external ear	0.735	0.265
N85 Other noninflammatory disorders of uterus, except cervix	0.734	0.266
H93 Other disorders of ear, not elsewhere classified	0.734	0.266
R47-R49 Symptoms and signs involving speech and voice	0.733	0.267
R58 Haemorrhage, not elsewhere classified	0.732	0.268
R57.0 Cardiogenic shock	0.731	0.269
N95.8 Other specified menopausal and perimenopausal disorders	0.730	0.270
R23.1 Pallor	0.730	0.270
T15-T19 Effects of foreign body entering through natural orifice	0.730	0.270
C34.2 Middle lobe, bronchus or lung	0.729	0.271
O20.0 Threatened abortion	0.728	0.272
N03 Chronic nephritic syndrome	0.728	0.272
N28.1 Cyst of kidney, acquired	0.726	0.274
O85-O92 Complications predominantly related to the puerperium	0.726	0.274
O23 Infections of genito-urinary tract in pregnancy	0.722	0.278
H65.9 Nonsuppurative otitis media, unspecified	0.721	0.279
D04 Carcinoma in situ of skin	0.721	0.279
N82 Fistulae involving female genital tract	0.720	0.280
M46 Other inflammatory spondylopathies	0.720	0.280
I08 Multiple valve diseases	0.719	0.281
H81.1 Benign paroxysmal vertigo	0.719	0.281
M47 Spondylosis	0.719	0.281
E65-E68 Obesity and other hyperalimentation	0.718	0.282
R30.0 Dysuria	0.717	0.283
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.716	0.284
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.716	0.284
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.715	0.285
R62 Lack of expected normal physiological development	0.715	0.285
R30.1 Vesical tenesmus	0.715	0.285
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.714	0.286
R68.0 Hypothermia, not associated with low environmental temperature	0.713	0.287
N75 Diseases of Bartholin's gland	0.712	0.288
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.710	0.290
C40-C41 Malignant neoplasms of bone and articular cartilage	0.710	0.290
C92.0 Acute myeloid leukaemia	0.709	0.291
N17 Acute renal failure	0.709	0.291
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.709	0.291
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.708	0.292
R63.1 Polydipsia	0.707	0.293
R36 Urethral discharge	0.707	0.293
R34 Anuria and oliguria	0.707	0.293
R32 Unspecified urinary incontinence	0.707	0.293
D02 Carcinoma in situ of middle ear and respiratory system	0.705	0.294
D01 Carcinoma in situ of other and unspecified digestive organs	0.705	0.294
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.705	0.294
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.705	0.295
H70 Mastoiditis and related conditions	0.705	0.295
H69 Other disorders of Eustachian tube	0.705	0.295
H68 Eustachian salpingitis and obstruction	0.705	0.295
H67 Otitis media in diseases classified elsewhere	0.705	0.295
T68 Hypothermia	0.705	0.295
B35-B49 Mycoses	0.704	0.296
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.704	0.296
S40 Superficial injury of shoulder and upper arm	0.703	0.297
D64.9 Anaemia, unspecified	0.703	0.297
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.702	0.298
S30 Superficial injury of abdomen, lower back and pelvis	0.702	0.298
T33-T35 Frostbite	0.702	0.298
T26-T28 Burns and corrosions confined to eye and internal organs	0.702	0.298
T20-T25 Burns and corrosions of external body surface, specified by site	0.702	0.298
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.702	0.298
T00-T07 Injuries involving multiple body regions	0.702	0.298
A50-A64 Infections with a predominantly sexual mode of transmission	0.700	0.300
C32 Malignant neoplasm of larynx	0.700	0.300
M47.9 Spondylosis, unspecified	0.699	0.301
D46 Myelodysplastic syndromes	0.699	0.301
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.699	0.301
Q80-Q89 Other congenital malformations	0.699	0.301
M65-M68 Disorders of synovium and tendon	0.699	0.301
H94 Other disorders of ear in diseases classified elsewhere	0.698	0.302
Q38-Q45 Other congenital malformations of the digestive system	0.698	0.302
N95.0 Postmenopausal bleeding	0.697	0.303
R61 Hyperhidrosis	0.696	0.304
I05 Rheumatic mitral valve diseases	0.695	0.305
D05.7 Other carcinoma in situ of breast	0.694	0.306
Q60-Q64 Congenital malformations of the urinary system	0.693	0.306
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.693	0.307
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.693	0.307
R63.6 Insufficient intake of food and water due to self neglect	0.691	0.309
R63.5 Abnormal weight gain	0.691	0.309
R63.3 Feeding difficulties and mismanagement	0.691	0.309
R63.2 Polyphagia	0.691	0.309
M86-M90 Other osteopathies	0.690	0.310
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.690	0.310
C38 Malignant neoplasm of heart, mediastinum and pleura	0.690	0.310
C31 Malignant neoplasm of accessory sinuses	0.690	0.310
C30 Malignant neoplasm of nasal cavity and middle ear	0.690	0.310
C37 Malignant neoplasm of thymus	0.690	0.310
C33 Malignant neoplasm of trachea	0.690	0.310
M40-M43 Deforming dorsopathies	0.690	0.310
R52.0 Acute pain	0.689	0.310
T51 Toxic effect of alcohol	0.689	0.310
E61 Deficiency of other nutrient elements	0.689	0.311
H66.3 Other chronic suppurative otitis media	0.689	0.311
B90-B94 Sequelae of infectious and parasitic diseases	0.686	0.314
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.686	0.314
B99-B99 Other infectious diseases	0.685	0.314
B85-B89 Pediculosis, acariasis and other infestations	0.685	0.314
B65-B83 Helminthiases	0.685	0.314
B50-B64 Protozoal diseases	0.685	0.314
B20-B24 Human immunodeficiency virus [HIV] disease	0.685	0.314
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.685	0.314
A75-A79 Rickettsioses	0.685	0.314
A70-A74 Other diseases caused by chlamydiae	0.685	0.314
A65-A69 Other spirochaetal diseases	0.685	0.314
A20-A28 Certain zoonotic bacterial diseases	0.685	0.314
A15-A19 Tuberculosis	0.685	0.314
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.684	0.316
S92 Fracture of foot, except ankle	0.684	0.316
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.683	0.317
C91 Lymphoid leukaemia	0.683	0.317
B25-B34 Other viral diseases	0.683	0.317
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.682	0.318
A49 Bacterial infection of unspecified site	0.681	0.319
R22.3 Localised swelling, mass and lump, upper limb	0.681	0.319
N03.9 Unspecified	0.681	0.319
D70-D77 Other diseases of blood and blood-forming organs	0.681	0.319
R68.3 Clubbing of fingers	0.680	0.320
R68.2 Dry mouth, unspecified	0.680	0.320
R68.1 Nonspecific symptoms peculiar to infancy	0.680	0.320
H65.4 Other chronic nonsuppurative otitis media	0.680	0.320
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.679	0.321
H91.8 Other specified hearing loss	0.679	0.321
H91.3 Deaf mutism, not elsewhere classified	0.679	0.321
H91.2 Sudden idiopathic hearing loss	0.679	0.321
H91.1 Presbycusis	0.679	0.321
H91.0 Ototoxic hearing loss	0.679	0.321
I30-I52 Other forms of heart disease	0.679	0.321
H65.1 Other acute nonsuppurative otitis media	0.679	0.321
H65.0 Acute serous otitis media	0.679	0.321
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.679	0.321
N27 Small kidney of unknown cause	0.679	0.321
N25 Disorders resulting from impaired renal tubular function	0.679	0.321
T79-T79 Certain early complications of trauma	0.678	0.322
F10.1 Harmful use	0.678	0.322
A02 Other Salmonella infections	0.677	0.323
C34.0 Main bronchus	0.677	0.323
D62 Acute posthaemorrhagic anaemia	0.676	0.324
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.676	0.324
T46 Poisoning by agents primarily affecting the cardiovascular system	0.676	0.324
C34.8 Overlapping lesion of bronchus and lung	0.676	0.324
C92.1 Chronic myeloid leukaemia	0.676	0.324
T78.4 Allergy, unspecified	0.675	0.325
C50.4 Upper-outer quadrant of breast	0.675	0.325
N85.8 Other specified noninflammatory disorders of uterus	0.675	0.325
A80-A89 Viral infections of the central nervous system	0.674	0.326
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.673	0.327
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.673	0.327
E70-E90 Metabolic disorders	0.673	0.327
C50.0 Nipple and areola	0.673	0.327
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.672	0.328
R60 Oedema, not elsewhere classified	0.672	0.328
Chapter XXII Codes for special purposes	0.671	0.328
C81 Hodgkin's disease	0.671	0.329
N80.8 Other endometriosis	0.671	0.329
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.670	0.330
D06.9 Cervix, unspecified	0.670	0.330
H81.2 Vestibular neuronitis	0.668	0.331
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.666	0.334
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.664	0.335
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.663	0.336
C95 Leukaemia of unspecified cell type	0.663	0.336
C94 Other leukaemias of specified cell type	0.663	0.336
C93 Monocytic leukaemia	0.663	0.336
C88 Malignant immunoproliferative diseases	0.663	0.336
C86 Other specified types of T/NK-cell lymphoma	0.663	0.336
C84 Peripheral and cutaneous T-cell lymphomas	0.663	0.336
H82 Vertiginous syndromes in diseases classified elsewhere	0.663	0.337
H66.4 Suppurative otitis media, unspecified	0.661	0.339
H66.2 Chronic atticoantral suppurative otitis media	0.661	0.339
H66.1 Chronic tubotympanic suppurative otitis media	0.661	0.339
H66.0 Acute suppurative otitis media	0.661	0.339
O08 Complications following abortion and ectopic and molar pregnancy	0.661	0.339
O07 Failed attempted abortion	0.661	0.339
O06 Unspecified abortion	0.661	0.339
O05 Other abortion	0.661	0.339
O01 Hydatidiform mole	0.661	0.339
C50.9 Breast, unspecified	0.661	0.339
M45 Ankylosing spondylitis	0.661	0.339
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.660	0.340
F70-F79 Mental retardation	0.660	0.340
F60-F69 Disorders of adult personality and behaviour	0.660	0.340
Q00-Q07 Congenital malformations of the nervous system	0.660	0.340
M91-M94 Chondropathies	0.658	0.342
S20 Superficial injury of thorax	0.658	0.342
S46 Injury of muscle and tendon at shoulder and upper arm level	0.658	0.342
N28.0 Ischaemia and infarction of kidney	0.658	0.342
B15-B19 Viral hepatitis	0.657	0.343
O26 Maternal care for other conditions predominantly related to pregnancy	0.657	0.343
H80 Otosclerosis	0.655	0.345
D63 Anaemia in chronic diseases classified elsewhere	0.654	0.346
Chapter XX External causes of morbidity and mortality	0.654	0.346
Q50-Q56 Congenital malformations of genital organs	0.654	0.346
O04.4 Incomplete, without complication	0.653	0.347
H74.8 Other specified disorders of middle ear and mastoid	0.652	0.348
S42 Fracture of shoulder and upper arm	0.652	0.348
C82.2 Large cell, follicular	0.652	0.348
D55-D59 Haemolytic anaemias	0.652	0.348
E61.1 Iron deficiency	0.652	0.348
F10.3 Withdrawal state	0.652	0.348
I60-I69 Cerebrovascular diseases	0.651	0.349
D45 Polycythaemia vera	0.651	0.349
A04 Other bacterial intestinal infections	0.650	0.350
M46.9 Inflammatory spondylopathy, unspecified	0.650	0.350
N17.9 Acute renal failure, unspecified	0.648	0.352
R23.3 Spontaneous ecchymoses	0.647	0.353
R23.2 Flushing	0.647	0.353
R23.0 Cyanosis	0.647	0.353
N98 Complications associated with artificial fertilisation	0.647	0.353
N91 Absent, scanty and rare menstruation	0.647	0.353
N96 Habitual aborter	0.647	0.353
D50-D53 Nutritional anaemias	0.646	0.354
E87 Other disorders of fluid, electrolyte and acid-base balance	0.646	0.354
T93 Sequelae of injuries of lower limb	0.646	0.354
M80-M85 Disorders of bone density and structure	0.646	0.354
R63.4 Abnormal weight loss	0.643	0.357
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.642	0.358
S70-S79 Injuries to the hip and thigh	0.642	0.358
D09.0 Bladder	0.641	0.359
M47.96 Spondylosis, unspecified (Lumbar region)	0.641	0.359
F22 Persistent delusional disorders	0.641	0.359
R57.9 Shock, unspecified	0.640	0.360
R57.8 Other shock	0.640	0.360
R57.1 Hypovolaemic shock	0.640	0.360
N84.9 Polyp of female genital tract, unspecified	0.640	0.360
N84.8 Polyp of other parts of female genital tract	0.640	0.360
N84.3 Polyp of vulva	0.640	0.360
N84.2 Polyp of vagina	0.640	0.360
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.639	0.361
A07 Other protozoal intestinal diseases	0.639	0.361
A06 Amoebiasis	0.639	0.361
A05 Other bacterial foodborne intoxications	0.639	0.361
A03 Shigellosis	0.639	0.361
A01 Typhoid and paratyphoid fevers	0.639	0.361
A00 Cholera	0.639	0.361
O24 Diabetes mellitus in pregnancy	0.638	0.362
O29 Complications of anaesthesia during pregnancy	0.638	0.362
O28 Abnormal findings on antenatal screening of mother	0.638	0.362
O22 Venous complications in pregnancy	0.638	0.362
O21 Excessive vomiting in pregnancy	0.638	0.362
O25 Malnutrition in pregnancy	0.638	0.362
Q20-Q28 Congenital malformations of the circulatory system	0.637	0.363
O20.9 Haemorrhage in early pregnancy, unspecified	0.636	0.364
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.636	0.364
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.636	0.364
Q35-Q37 Cleft lip and cleft palate	0.636	0.364
Q30-Q34 Congenital malformations of the respiratory system	0.636	0.364
N80.1 Endometriosis of ovary	0.635	0.365
T63 Toxic effect of contact with venomous animals	0.635	0.365
D61 Other aplastic anaemias	0.635	0.365
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.634	0.366
A08 Viral and other specified intestinal infections	0.634	0.366
N71 Inflammatory disease of uterus, except cervix	0.633	0.366
C50.3 Lower-inner quadrant of breast	0.633	0.367
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.633	0.367
I08.1 Disorders of both mitral and tricuspid valves	0.632	0.368
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.632	0.368
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.632	0.368
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.632	0.368
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.632	0.368
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.632	0.368
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.632	0.368
H73.8 Other specified disorders of tympanic membrane	0.632	0.368
F99-F99 Unspecified mental disorder	0.631	0.369
A48 Other bacterial diseases, not elsewhere classified	0.630	0.369
H81.9 Disorder of vestibular function, unspecified	0.630	0.370
H81.8 Other disorders of vestibular function	0.630	0.370
H81.4 Vertigo of central origin	0.630	0.370
H81.3 Other peripheral vertigo	0.630	0.370
S52 Fracture of forearm	0.630	0.370
R81 Glycosuria	0.630	0.370
N95.1 Menopausal and female climacteric states	0.630	0.370
R54 Senility	0.629	0.370
N75.0 Cyst of Bartholin's gland	0.629	0.370
O03.8 Complete or unspecified, with other and unspecified complications	0.628	0.371
O03.7 Complete or unspecified, complicated by embolism	0.628	0.371
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.628	0.371
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.628	0.371
O03.3 Incomplete, with other and unspecified complications	0.628	0.371
O03.2 Incomplete, complicated by embolism	0.628	0.371
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.628	0.371
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.628	0.371
C50.8 Overlapping lesion of breast	0.628	0.372
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.628	0.372
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.627	0.373
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.626	0.374
T75 Effects of other external causes	0.625	0.375
T74 Maltreatment syndromes	0.625	0.375
T73 Effects of other deprivation	0.625	0.375
T70 Effects of air pressure and water pressure	0.625	0.375
T69 Other effects of reduced temperature	0.625	0.375
T67 Effects of heat and light	0.625	0.375
T71 Asphyxiation	0.625	0.375
T66 Unspecified effects of radiation	0.625	0.375
N92.4 Excessive bleeding in the premenopausal period	0.625	0.375
H83 Other diseases of inner ear	0.624	0.376
H90.3 Sensorineural hearing loss, bilateral	0.624	0.376
I42 Cardiomyopathy	0.624	0.376
S22 Fracture of rib(s), sternum and thoracic spine	0.624	0.376
S49 Other and unspecified injuries of shoulder and upper arm	0.623	0.376
S48 Traumatic amputation of shoulder and upper arm	0.623	0.376
S45 Injury of blood vessels at shoulder and upper arm level	0.623	0.376
S44 Injury of nerves at shoulder and upper arm level	0.623	0.376
S41 Open wound of shoulder and upper arm	0.623	0.376
S47 Crushing injury of shoulder and upper arm	0.623	0.376
N85.0 Endometrial glandular hyperplasia	0.623	0.377
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.622	0.378
F29 Unspecified nonorganic psychosis	0.621	0.379
E66 Obesity	0.621	0.379
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.620	0.379
R49 Voice disturbances	0.619	0.381
O00 Ectopic pregnancy	0.619	0.381
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.619	0.381
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.619	0.381
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.619	0.381
T41 Poisoning by anaesthetics and therapeutic gases	0.619	0.381
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.619	0.381
T36 Poisoning by systemic antibiotics	0.619	0.381
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.618	0.382
M47.99 Spondylosis, unspecified (Site unspecified)	0.616	0.384
R30.9 Painful micturition, unspecified	0.616	0.384
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.615	0.385
A49.0 Staphylococcal infection, unspecified	0.614	0.386
S32 Fracture of lumbar spine and pelvis	0.613	0.387
E40-E46 Malnutrition	0.612	0.387
N20-N23 Urolithiasis	0.612	0.388
M60-M63 Disorders of muscles	0.612	0.388
M00-M03 Infectious arthropathies	0.612	0.388
M50-M54 Other dorsopathies	0.612	0.388
I05.9 Mitral valve disease, unspecified	0.611	0.389
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.610	0.389
D07.5 Prostate	0.610	0.390
I08.2 Disorders of both aortic and tricuspid valves	0.609	0.391
T39.0 Salicylates	0.609	0.391
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.608	0.392
S43.0 Dislocation of shoulder joint	0.608	0.392
S81 Open wound of lower leg	0.608	0.392
M48 Other spondylopathies	0.608	0.392
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.608	0.392
F12 Mental and behavioural disorders due to use of cannabinoids	0.607	0.393
O80 Single spontaneous delivery	0.607	0.393
R50.2 Drug-induced fever	0.605	0.394
R50.1 Persistent fever	0.605	0.394
I09 Other rheumatic heart diseases	0.605	0.395
H72 Perforation of tympanic membrane	0.604	0.396
N11 Chronic tubulo-interstitial nephritis	0.603	0.397
R80 Isolated proteinuria	0.601	0.398
I45 Other conduction disorders	0.601	0.399
F84 Pervasive developmental disorders	0.600	0.400
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.600	0.400
E26 Hyperaldosteronism	0.599	0.401
F81 Specific developmental disorders of scholastic skills	0.599	0.401
F31 Bipolar affective disorder	0.599	0.401
N92.5 Other specified irregular menstruation	0.599	0.401
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.598	0.402
C83.7 Burkitt's tumour	0.598	0.402
C83.6 Undifferentiated (diffuse)	0.598	0.402
C83.5 Lymphoblastic (diffuse)	0.598	0.402
C83.4 Immunoblastic (diffuse)	0.598	0.402
C83.2 Mixed small and large cell (diffuse)	0.598	0.402
C83.1 Small cleaved cell (diffuse)	0.598	0.402

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations