TreeWAS – Variant ID: rs16858228

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N20.1 Calculus of ureter	0.000	0.985	0.015
N20.0 Calculus of kidney	0.000	0.986	0.014
N20 Calculus of kidney and ureter	0.000	0.986	0.014
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.989	0.011
M06.9 Rheumatoid arthritis, unspecified	0.000	0.990	0.010
N20.9 Urinary calculus, unspecified	0.000	0.990	0.010
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.990	0.010
N20.2 Calculus of kidney with calculus of ureter	0.000	0.990	0.010
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.991	0.009
G40.9 Epilepsy, unspecified	0.000	0.991	0.009
K92.1 Melaena	0.000	0.991	0.009
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.991	0.009
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.008	0.992	0.000
D50.9 Iron deficiency anaemia, unspecified	0.008	0.992	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.992	0.008
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.992	0.008
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.992	0.008
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.992	0.008
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.992	0.008
N20-N23 Urolithiasis	0.000	0.993	0.007
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.993	0.007
K92 Other diseases of digestive system	0.000	0.993	0.007
K92.0 Haematemesis	0.000	0.993	0.007
N23 Unspecified renal colic	0.000	0.994	0.006
N22 Calculus of urinary tract in diseases classified elsewhere	0.000	0.994	0.005
N21 Calculus of lower urinary tract	0.000	0.995	0.005
M06 Other rheumatoid arthritis	0.000	0.995	0.005
K92.8 Other specified diseases of digestive system	0.000	0.995	0.005
K92.2 Gastro-intestinal haemorrhage, unspecified	0.000	0.995	0.005
K92.9 Disease of digestive system, unspecified	0.000	0.995	0.005
C44.3 Skin of other and unspecified parts of face	0.005	0.995	0.000
D50 Iron deficiency anaemia	0.005	0.995	0.000
S00.7 Multiple superficial injuries of head	0.005	0.995	0.000
R56.8 Other and unspecified convulsions	0.000	0.995	0.005
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.005	0.995	0.000
H25.9 Senile cataract, unspecified	0.000	0.995	0.005
S00 Superficial injury of head	0.005	0.995	0.000
S00.9 Superficial injury of head, part unspecified	0.005	0.995	0.000
G40 Epilepsy	0.000	0.996	0.004
S00.8 Superficial injury of other parts of head	0.004	0.996	0.000
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.000	0.996	0.004
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.000	0.996	0.004
T83.1 Mechanical complication of other urinary devices and implants	0.004	0.996	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.004	0.996	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.000	0.996	0.004
N21.8 Other lower urinary tract calculus	0.000	0.996	0.004
N21.1 Calculus in urethra	0.000	0.996	0.004
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.996	0.004
S00.0 Superficial injury of scalp	0.004	0.996	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.004	0.996	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.996	0.004
M06.4 Inflammatory polyarthropathy	0.000	0.996	0.004
M06.3 Rheumatoid nodule	0.000	0.996	0.004
M06.2 Rheumatoid bursitis	0.000	0.996	0.004
M06.1 Adult-onset Still's disease	0.000	0.996	0.004
N21.0 Calculus in bladder	0.000	0.996	0.004
T83.3 Mechanical complication of intra-uterine contraceptive device	0.004	0.996	0.000
S00.3 Superficial injury of nose	0.004	0.996	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.996	0.004
D50.1 Sideropenic dysphagia	0.004	0.996	0.000
S00.5 Superficial injury of lip and oral cavity	0.004	0.996	0.000
S00.4 Superficial injury of ear	0.004	0.996	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.004	0.996	0.000
S02 Fracture of skull and facial bones	0.004	0.996	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.996	0.004
H25.0 Senile incipient cataract	0.000	0.996	0.004
T83.0 Mechanical complication of urinary (indwelling) catheter	0.003	0.996	0.000
G40.8 Other epilepsy	0.000	0.997	0.003
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.997	0.003
G40.5 Special epileptic syndromes	0.000	0.997	0.003
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.997	0.003
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.997	0.003
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.997	0.003
S02.5 Fracture of tooth	0.003	0.997	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.003	0.997	0.000
H25 Senile cataract	0.000	0.997	0.003
S02.50 Fracture of tooth (closed)	0.003	0.997	0.000
S02.2 Fracture of nasal bones	0.003	0.997	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.003	0.997	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.003	0.997	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.003	0.997	0.000
T83.2 Mechanical complication of graft of urinary organ	0.003	0.997	0.000
S00-S09 Injuries to the head	0.003	0.997	0.000
S02.6 Fracture of mandible	0.003	0.997	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.003	0.997	0.000
S02.20 Fracture of nasal bones (closed)	0.003	0.997	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.003	0.997	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.997	0.003
M06.18 Adult-onset Still's disease (Other)	0.000	0.997	0.003
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.997	0.003
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.997	0.003
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.997	0.003
M06.14 Adult-onset Still's disease (Hand)	0.000	0.997	0.003
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.997	0.003
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.997	0.003
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.997	0.003
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.997	0.003
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.997	0.003
M06.28 Rheumatoid bursitis (Other)	0.000	0.997	0.003
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.997	0.003
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.997	0.003
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.997	0.003
M06.24 Rheumatoid bursitis (Hand)	0.000	0.997	0.003
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.997	0.003
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.997	0.003
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.997	0.003
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.997	0.003
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.997	0.003
M06.38 Rheumatoid nodule (Other)	0.000	0.997	0.003
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.997	0.003
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.997	0.003
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.997	0.003
M06.34 Rheumatoid nodule (Hand)	0.000	0.997	0.003
M06.33 Rheumatoid nodule (Forearm)	0.000	0.997	0.003
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.997	0.003
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.997	0.003
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.997	0.003
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.997	0.003
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.997	0.003
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.997	0.003
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.997	0.003
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.997	0.003
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.997	0.003
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.997	0.003
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.997	0.003
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.997	0.003
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.997	0.003
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.997	0.003
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.997	0.003
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.997	0.003
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.997	0.003
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.997	0.003
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.997	0.003
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.997	0.003
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.997	0.003
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.997	0.003
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.997	0.003
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.997	0.003
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.003	0.997	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.003	0.997	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.997	0.003
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.997	0.003
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.997	0.003
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.997	0.003
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.997	0.003
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.997	0.003
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.997	0.003
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.997	0.003
S02.60 Fracture of mandible (closed)	0.003	0.997	0.000
R56 Convulsions, not elsewhere classified	0.000	0.997	0.003
S02.8 Fractures of other skull and facial bones	0.003	0.997	0.000
S01.0 Open wound of scalp	0.000	0.997	0.003
S02.4 Fracture of malar and maxillary bones	0.003	0.997	0.000
T87 Complications peculiar to reattachment and amputation	0.003	0.997	0.000
H25.1 Senile nuclear cataract	0.000	0.997	0.003
R55 Syncope and collapse	0.000	0.997	0.003
S02.9 Fracture of skull and facial bones, part unspecified	0.003	0.997	0.000
S02.7 Multiple fractures involving skull and facial bones	0.003	0.997	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.003	0.997	0.000
S02.3 Fracture of orbital floor	0.003	0.997	0.000
S91.3 Open wound of other parts of foot	0.003	0.997	0.000
S02.0 Fracture of vault of skull	0.003	0.997	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.997	0.003
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.003	0.997	0.000
S02.51 Fracture of tooth (open)	0.003	0.997	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.003	0.997	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.003	0.997	0.000
H25.2 Senile cataract, morgagnian type	0.000	0.997	0.003
T85 Complications of other internal prosthetic devices, implants and grafts	0.003	0.997	0.000
T86 Failure and rejection of transplanted organs and tissues	0.003	0.997	0.000
S02.21 Fracture of nasal bones (open)	0.003	0.997	0.000
S02.1 Fracture of base of skull	0.003	0.997	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.003	0.997	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.003	0.997	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.997	0.002
S00.1 Contusion of eyelid and periocular area	0.002	0.997	0.000
S05 Injury of eye and orbit	0.003	0.997	0.000
T87.6 Other and unspecified complications of amputation stump	0.003	0.997	0.000
S02.61 Fracture of mandible (open)	0.002	0.997	0.000
S08 Traumatic amputation of part of head	0.002	0.997	0.000
S07 Crushing injury of head	0.002	0.997	0.000
S04 Injury of cranial nerves	0.002	0.997	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.002	0.997	0.000
S91 Open wound of ankle and foot	0.003	0.997	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.003	0.997	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.997	0.003
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.997	0.002
T85.2 Mechanical complication of intraocular lens	0.003	0.997	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.003	0.997	0.000
T87.4 Infection of amputation stump	0.002	0.997	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.002	0.997	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.997	0.002
S90-S99 Injuries to the ankle and foot	0.002	0.997	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.002	0.997	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
R56.0 Febrile convulsions	0.000	0.998	0.002
T84.0 Mechanical complication of internal joint prosthesis	0.002	0.998	0.000
S02.81 Fractures of other skull and facial bones (open)	0.002	0.998	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.002	0.998	0.000
S06 Intracranial injury	0.002	0.998	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.002	0.998	0.000
D50.8 Other iron deficiency anaemias	0.002	0.998	0.000
T87.5 Necrosis of amputation stump	0.002	0.998	0.000
T87.3 Neuroma of amputation stump	0.002	0.998	0.000
T87.2 Complications of other reattached body part	0.002	0.998	0.000
T87.1 Complications of reattached (part of) lower extremity	0.002	0.998	0.000
T87.0 Complications of reattached (part of) upper extremity	0.002	0.998	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.002	0.998	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.002	0.998	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.002	0.998	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.002	0.998	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.002	0.998	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.002	0.998	0.000
S02.31 Fracture of orbital floor (open)	0.002	0.998	0.000
S09 Other and unspecified injuries of head	0.002	0.998	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.002	0.998	0.000
S02.30 Fracture of orbital floor (closed)	0.002	0.998	0.000
N80.3 Endometriosis of pelvic peritoneum	0.002	0.998	0.000
T88.5 Other complications of anaesthesia	0.002	0.998	0.000
S02.01 Fracture of vault of skull (open)	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.002	0.998	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T80.6 Other serum reactions	0.002	0.998	0.000
T80.5 Anaphylactic shock due to serum	0.002	0.998	0.000
T80.4 Rh incompatibility reaction	0.002	0.998	0.000
T80.3 ABO incompatibility reaction	0.002	0.998	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.002	0.998	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.002	0.998	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.002	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.998	0.002
S02.11 Fracture of base of skull (open)	0.002	0.998	0.000
S05.8 Other injuries of eye and orbit	0.002	0.998	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.002	0.998	0.000
T86.4 Liver transplant failure and rejection	0.002	0.998	0.000
T86.3 Heart-lung transplant failure and rejection	0.002	0.998	0.000
T86.2 Heart transplant failure and rejection	0.002	0.998	0.000
T86.1 Kidney transplant failure and rejection	0.002	0.998	0.000
T86.0 Bone-marrow transplant rejection	0.002	0.998	0.000
S05.9 Injury of eye and orbit, part unspecified	0.002	0.998	0.000
S05.7 Avulsion of eye	0.002	0.998	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.002	0.998	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.002	0.998	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.002	0.998	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.002	0.998	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.002	0.998	0.000
S05.1 Contusion of eyeball and orbital tissues	0.002	0.998	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.002	0.998	0.000
S06.0 Concussion	0.002	0.998	0.000
S02.00 Fracture of vault of skull (closed)	0.002	0.998	0.000
T88.9 Complication of surgical and medical care, unspecified	0.002	0.998	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.002	0.998	0.000
T88.2 Shock due to anaesthesia	0.002	0.998	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.002	0.998	0.000
T88.0 Infection following immunisation	0.002	0.998	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.002	0.998	0.000
S03.4 Sprain and strain of jaw	0.002	0.998	0.000
S03.3 Dislocation of other and unspecified parts of head	0.002	0.998	0.000
S03.2 Dislocation of tooth	0.002	0.998	0.000
S03.1 Dislocation of septal cartilage of nose	0.002	0.998	0.000
S03.0 Dislocation of jaw	0.002	0.998	0.000
S04.9 Injury of unspecified cranial nerve	0.002	0.998	0.000
S04.8 Injury of other cranial nerves	0.002	0.998	0.000
S04.7 Injury of accessory nerve	0.002	0.998	0.000
S04.6 Injury of acoustic nerve	0.002	0.998	0.000
S04.5 Injury of facial nerve	0.002	0.998	0.000
S04.4 Injury of abducent nerve	0.002	0.998	0.000
S04.3 Injury of trigeminal nerve	0.002	0.998	0.000
S04.2 Injury of trochlear nerve	0.002	0.998	0.000
S04.1 Injury of oculomotor nerve	0.002	0.998	0.000
S04.0 Injury of optic nerve and pathways	0.002	0.998	0.000
S07.9 Crushing injury of head, part unspecified	0.002	0.998	0.000
S07.8 Crushing injury of other parts of head	0.002	0.998	0.000
S07.1 Crushing injury of skull	0.002	0.998	0.000
S07.0 Crushing injury of face	0.002	0.998	0.000
S08.9 Traumatic amputation of unspecified part of head	0.002	0.998	0.000
S08.8 Traumatic amputation of other parts of head	0.002	0.998	0.000
S08.1 Traumatic amputation of ear	0.002	0.998	0.000
S08.0 Avulsion of scalp	0.002	0.998	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
S91.0 Open wound of ankle	0.002	0.998	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.998	0.002
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
J93.9 Pneumothorax, unspecified	0.000	0.998	0.002
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.002	0.998	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.998	0.002
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.002
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
S86.8 Injury of other muscles and tendons at lower leg level	0.002	0.998	0.000
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
S10-S19 Injuries to the neck	0.002	0.998	0.000
N13.3 Other and unspecified hydronephrosis	0.000	0.998	0.002
S92 Fracture of foot, except ankle	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
S06.00 Concussion (without open intracranial wound)	0.002	0.998	0.000
S06.8 Other intracranial injuries	0.002	0.998	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.002	0.998	0.000
H25.8 Other senile cataract	0.000	0.998	0.002
S06.9 Intracranial injury, unspecified	0.002	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.002	0.998	0.000
S06.3 Focal brain injury	0.002	0.998	0.000
S06.1 Traumatic cerebral oedema	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.002	0.998	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.002	0.998	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
N13 Obstructive and reflux uropathy	0.000	0.998	0.002
S09.8 Other specified injuries of head	0.002	0.998	0.000
S09.7 Multiple injuries of head	0.002	0.998	0.000
S09.2 Traumatic rupture of ear drum	0.002	0.998	0.000
S09.1 Injury of muscle and tendon of head	0.002	0.998	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.002	0.998	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.002	0.998	0.000
K90-K93 Other diseases of the digestive system	0.000	0.998	0.002
S06.2 Diffuse brain injury	0.002	0.998	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.002	0.998	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.002	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.002	0.998	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.002	0.998	0.000
S40-S49 Injuries to the shoulder and upper arm	0.002	0.998	0.000
R60.0 Localised oedema	0.000	0.998	0.002
S83.6 Sprain and strain of other and unspecified parts of knee	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
T88.4 Failed or difficult intubation	0.002	0.998	0.000
T33-T35 Frostbite	0.002	0.998	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.002	0.998	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.002	0.998	0.000
T00-T07 Injuries involving multiple body regions	0.002	0.998	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.002	0.998	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.002	0.998	0.000
D50-D53 Nutritional anaemias	0.002	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.002	0.998	0.000
S70 Superficial injury of hip and thigh	0.002	0.998	0.000
S86 Injury of muscle and tendon at lower leg level	0.002	0.998	0.000
T63 Toxic effect of contact with venomous animals	0.002	0.998	0.000
M05-M14 Inflammatory polyarthropathies	0.000	0.998	0.002
S70-S79 Injuries to the hip and thigh	0.002	0.998	0.000
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
S06.01 Concussion (with open intracranial wound)	0.002	0.998	0.000
T58 Toxic effect of carbon monoxide	0.002	0.998	0.000
T66-T78 Other and unspecified effects of external causes	0.002	0.998	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.998	0.002
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.998	0.002
M05.2 Rheumatoid vasculitis	0.000	0.998	0.002
M05.1 Rheumatoid lung disease	0.000	0.998	0.002
M05.0 Felty's syndrome	0.000	0.998	0.002
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.998	0.002
S06.5 Traumatic subdural haemorrhage	0.001	0.998	0.001
T63.4 Venom of other arthropods	0.002	0.998	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.002	0.998	0.000
Y84.8 Other medical procedures	0.000	0.998	0.002
N13.4 Hydroureter	0.000	0.998	0.002
N80.9 Endometriosis, unspecified	0.002	0.998	0.000
R61.9 Hyperhidrosis, unspecified	0.000	0.998	0.002
S46 Injury of muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
T79-T79 Certain early complications of trauma	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.001	0.998	0.000
R59.1 Generalised enlarged lymph nodes	0.000	0.998	0.002
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.998	0.000
S94.1 Injury of medial plantar nerve	0.002	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.998	0.000
S95.1 Injury of plantar artery of foot	0.002	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.002	0.998	0.000
S97.0 Crushing injury of ankle	0.002	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.002	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.002	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.002	0.998	0.000
S98.1 Traumatic amputation of one toe	0.002	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.002	0.998	0.000
S99.9 Unspecified injury of ankle and foot	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.002	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.002	0.998	0.000
S19 Other and unspecified injuries of neck	0.002	0.998	0.000
S17 Crushing injury of neck	0.002	0.998	0.000
S15 Injury of blood vessels at neck level	0.002	0.998	0.000
S14 Injury of nerves and spinal cord at neck level	0.002	0.998	0.000
S12 Fracture of neck	0.002	0.998	0.000
S11 Open wound of neck	0.002	0.998	0.000
S10 Superficial injury of neck	0.002	0.998	0.000
S18 Traumatic amputation at neck level	0.002	0.998	0.000
S16 Injury of muscle and tendon at neck level	0.002	0.998	0.000
T91 Sequelae of injuries of neck and trunk	0.002	0.998	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.002	0.998	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.001	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
S90.0 Contusion of ankle	0.002	0.998	0.000
D52 Folate deficiency anaemia	0.002	0.998	0.000
S01 Open wound of head	0.000	0.998	0.001
S80-S89 Injuries to the knee and lower leg	0.002	0.998	0.000
S60-S69 Injuries to the wrist and hand	0.002	0.998	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.001	0.998	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.001	0.998	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.001	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.001	0.998	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.001	0.998	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.001	0.998	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.001	0.998	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.001	0.998	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.001	0.998	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.001	0.998	0.000
L98.7 Excessive and redundant skin and subcutaneous tissue	0.002	0.998	0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue	0.002	0.998	0.000
L98.5 Mucinosis of skin	0.002	0.998	0.000
L98.3 Eosinophilic cellulitis [Wells]	0.002	0.998	0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]	0.002	0.998	0.000
L98.1 Factitial dermatitis	0.002	0.998	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.002	0.998	0.000
N80 Endometriosis	0.002	0.998	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.998	0.002
N13.6 Pyonephrosis	0.000	0.998	0.002
S83.2 Tear of meniscus, current	0.002	0.998	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.001	0.998	0.000
R61 Hyperhidrosis	0.000	0.998	0.002
T65 Toxic effect of other and unspecified substances	0.002	0.998	0.000
T62 Toxic effect of other noxious substances eaten as food	0.002	0.998	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.002	0.998	0.000
T60 Toxic effect of pesticides	0.002	0.998	0.000
T59 Toxic effect of other gases, fumes and vapours	0.002	0.998	0.000
T57 Toxic effect of other inorganic substances	0.002	0.998	0.000
T56 Toxic effect of metals	0.002	0.998	0.000
T54 Toxic effect of corrosive substances	0.002	0.998	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.002	0.998	0.000
T52 Toxic effect of organic solvents	0.002	0.998	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.002	0.998	0.000
T55 Toxic effect of soaps and detergents	0.002	0.998	0.000
L98.0 Pyogenic granuloma	0.002	0.998	0.000
S83.7 Injury to multiple structures of knee	0.002	0.998	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.002	0.998	0.000
S83.3 Tear of articular cartilage of knee, current	0.002	0.998	0.000
S83.1 Dislocation of knee	0.002	0.998	0.000
S83.0 Dislocation of patella	0.002	0.998	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.998	0.002
R53 Malaise and fatigue	0.000	0.998	0.002
S40 Superficial injury of shoulder and upper arm	0.002	0.998	0.000
T14 Injury of unspecified body region	0.002	0.998	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.001	0.998	0.000
L98.4 Chronic ulcer of skin, not elsewhere classified	0.002	0.998	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.001	0.998	0.000
S13.5 Sprain and strain of thyroid region	0.001	0.998	0.000
S13.3 Multiple dislocations of neck	0.001	0.998	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.001	0.998	0.000
S13.1 Dislocation of cervical vertebra	0.001	0.998	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.001	0.998	0.000
S70.0 Contusion of hip	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations