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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16894060
log Bayes Factor = 62.9751
Chromosome 6   position 28,362,471  (GRCh37) Explore rs16894060 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.997 0.003 0.000
E16 Other disorders of pancreatic internal secretion
0.996 0.004 0.000
E16.2 Hypoglycaemia, unspecified
0.995 0.005 0.000
E00-E07 Disorders of thyroid gland
0.995 0.005 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.994 0.006 0.000
E05.9 Thyrotoxicosis, unspecified
0.993 0.007 0.000
E10.3 With ophthalmic complications
0.984 0.016 0.000
E20-E35 Disorders of other endocrine glands
0.963 0.037 0.000
E27 Other disorders of adrenal gland
0.943 0.057 0.000
E27.1 Primary adrenocortical insufficiency
0.935 0.065 0.000
E03 Other hypothyroidism
0.914 0.086 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.904 0.096 0.000
E10.1 With ketoacidosis
0.896 0.104 0.000
E14 Unspecified diabetes mellitus
0.895 0.105 0.000
E03.9 Hypothyroidism, unspecified
0.869 0.131 0.000
E13 Other specified diabetes mellitus
0.845 0.155 0.000
E10.2 With renal complications
0.841 0.159 0.000
E10.0 With coma
0.811 0.189 0.000
E29 Testicular dysfunction
0.805 0.195 0.000
E20 Hypoparathyroidism
0.798 0.202 0.000
E31 Polyglandular dysfunction
0.776 0.224 0.000
E10.4 With neurological complications
0.775 0.225 0.000
E14.3 With ophthalmic complications
0.775 0.225 0.000
E05.8 Other thyrotoxicosis
0.773 0.227 0.000
R31 Unspecified haematuria
0.000 0.228 0.772
E24 Cushing's syndrome
0.768 0.232 0.000
E40-E46 Malnutrition
0.763 0.236 0.000
E25 Adrenogenital disorders
0.747 0.253 0.000
E14.9 Without complications
0.738 0.262 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.735 0.265 0.000
E13.9 Without complications
0.734 0.266 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.732 0.268 0.000
E10.7 With multiple complications
0.728 0.271 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.727 0.273 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.715 0.285 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.714 0.286 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.714 0.286 0.000
E16.4 Abnormal secretion of gastrin
0.714 0.286 0.000
E16.3 Increased secretion of glucagon
0.714 0.286 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.713 0.287 0.000
E00 Congenital iodine-deficiency syndrome
0.713 0.287 0.000
E05.5 Thyroid crisis or storm
0.713 0.287 0.000
E05.4 Thyrotoxicosis factitia
0.713 0.287 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.713 0.287 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.706 0.294 0.000
E23 Hypofunction and other disorders of pituitary gland
0.700 0.300 0.000
E34 Other endocrine disorders
0.698 0.302 0.000
E29.1 Testicular hypofunction
0.691 0.309 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.691 0.309 0.000
E32 Diseases of thymus
0.691 0.309 0.000
E30 Disorders of puberty, not elsewhere classified
0.691 0.309 0.000
E27.2 Addisonian crisis
0.689 0.311 0.000
E14.5 With peripheral circulatory complications
0.686 0.314 0.000
E14.1 With ketoacidosis
0.683 0.317 0.000
E16.1 Other hypoglycaemia
0.679 0.321 0.000
E20.9 Hypoparathyroidism, unspecified
0.679 0.321 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.676 0.324 0.000
E27.5 Adrenomedullary hyperfunction
0.676 0.324 0.000
E27.0 Other adrenocortical overactivity
0.676 0.324 0.000
E27.9 Disorder of adrenal gland, unspecified
0.672 0.328 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.667 0.333 0.000
K90 Intestinal malabsorption
0.657 0.343 0.000
E14.4 With neurological complications
0.656 0.344 0.000
E03.5 Myxoedema coma
0.656 0.344 0.000
E03.4 Atrophy of thyroid (acquired)
0.656 0.344 0.000
E03.3 Postinfectious hypothyroidism
0.656 0.344 0.000
E10.5 With peripheral circulatory complications
0.655 0.345 0.000
E10.6 With other specified complications
0.650 0.350 0.000
E14.2 Withrenal complications
0.645 0.355 0.000
E14.7 With multiple complications
0.642 0.358 0.000
E14.0 With coma
0.642 0.358 0.000
E31.0 Autoimmune polyglandular failure
0.642 0.358 0.000
E14.6 With other specified complications
0.641 0.359 0.000
E24.0 Pituitary-dependent Cushing's disease
0.641 0.359 0.000
E03.1 Congenital hypothyroidism without goitre
0.635 0.365 0.000
E13.8 With unspecified complications
0.605 0.394 0.000
E13.7 With multiple complications
0.605 0.394 0.000
E13.6 With other specified complications
0.605 0.394 0.000
E13.5 With peripheral circulatory complications
0.605 0.394 0.000
E13.4 With neurological complications
0.605 0.394 0.000
E13.2 With renal complications
0.605 0.394 0.000
E13.1 With ketoacidosis
0.605 0.394 0.000
E13.0 With coma
0.605 0.394 0.000
E13.3 With ophthalmic complications
0.604 0.396 0.000
E24.2 Drug-induced Cushing's syndrome
0.599 0.401 0.000
E46 Unspecified protein-energy malnutrition
0.594 0.406 0.000
E07 Other disorders of thyroid
0.594 0.406 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.592 0.408 0.000
E34.9 Endocrine disorder, unspecified
0.585 0.415 0.000
E29.9 Testicular dysfunction, unspecified
0.577 0.423 0.000
E29.8 Other testicular dysfunction
0.577 0.423 0.000
E29.0 Testicular hyperfunction
0.577 0.423 0.000
E20.8 Other hypoparathyroidism
0.572 0.428 0.000
E20.1 Pseudohypoparathyroidism
0.572 0.428 0.000
E20.0 Idiopathic hypoparathyroidism
0.572 0.428 0.000
E24.8 Other Cushing's syndrome
0.569 0.430 0.000
E31.9 Polyglandular dysfunction, unspecified
0.556 0.444 0.000
E31.8 Other polyglandular dysfunction
0.556 0.444 0.000
E31.1 Polyglandular hyperfunction
0.556 0.444 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.553 0.447 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.550 0.449 0.000
E24.3 Ectopic ACTH syndrome
0.550 0.449 0.000
E24.1 Nelson's syndrome
0.550 0.449 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.547 0.452 0.000
E45 Retarded development following protein-energy malnutrition
0.547 0.452 0.000
E43 Unspecified severe protein-energy malnutrition
0.547 0.452 0.000
E42 Marasmic kwashiorkor
0.547 0.452 0.000
E41 Nutritional marasmus
0.547 0.452 0.000
E40 Kwashiorkor
0.547 0.452 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.545 0.455 0.000
E25.9 Adrenogenital disorder, unspecified
0.536 0.464 0.000
E25.8 Other adrenogenital disorders
0.536 0.464 0.000
E26 Hyperaldosteronism
0.526 0.473 0.000
E23.7 Disorder of pituitary gland, unspecified
0.526 0.474 0.000
E34.3 Short stature, not elsewhere classified
0.517 0.483 0.000
K90.8 Other intestinal malabsorption
0.516 0.484 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.511 0.489 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.511 0.489 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.511 0.489 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.511 0.489 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.511 0.489 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.511 0.489 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.511 0.489 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.511 0.489 0.000
E14.8 With unspecified complications
0.507 0.493 0.000
E23.2 Diabetes insipidus
0.506 0.494 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.502 0.498 0.000
E23.1 Drug-induced hypopituitarism
0.502 0.498 0.000
E22 Hyperfunction of pituitary gland
0.500 0.500 0.000
E34.5 Androgen resistance syndrome
0.500 0.500 0.000
E34.4 Constitutional tall stature
0.500 0.500 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.500 0.500 0.000
E34.1 Other hypersecretion of intestinal hormones
0.500 0.500 0.000
E28 Ovarian dysfunction
0.499 0.501 0.000
E10.8 With unspecified complications
0.498 0.502 0.000
E23.6 Other disorders of pituitary gland
0.496 0.504 0.000
E30.9 Disorder of puberty, unspecified
0.495 0.505 0.000
E30.8 Other disorders of puberty
0.495 0.505 0.000
E30.1 Precocious puberty
0.495 0.505 0.000
E30.0 Delayed puberty
0.495 0.505 0.000
E32.9 Disease of thymus, unspecified
0.495 0.505 0.000
E32.8 Other diseases of thymus
0.495 0.505 0.000
E32.1 Abscess of thymus
0.495 0.505 0.000
E32.0 Persistent hyperplasia of thymus
0.495 0.505 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.495 0.505 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.495 0.505 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.495 0.505 0.000
K90.9 Intestinal malabsorption, unspecified
0.494 0.506 0.000
E07.8 Other specified disorders of thyroid
0.489 0.511 0.000
E23.0 Hypopituitarism
0.485 0.515 0.000
E06 Thyroiditis
0.471 0.528 0.000
K90.3 Pancreatic steatorrhoea
0.471 0.529 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.471 0.529 0.000
K90.1 Tropical sprue
0.471 0.529 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.464 0.536 0.000
E03.8 Other specified hypothyroidism
0.460 0.539 0.000
E34.8 Other specified endocrine disorders
0.434 0.565 0.000
E24.9 Cushing's syndrome, unspecified
0.428 0.572 0.000
E07.1 Dyshormogenetic goitre
0.426 0.574 0.000
E07.0 Hypersecretion of calcitonin
0.426 0.574 0.000
E34.0 Carcinoid syndrome
0.423 0.577 0.000
E83 Disorders of mineral metabolism
0.003 0.585 0.413
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.412 0.588 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.605 0.394
E27.8 Other specified disorders of adrenal gland
0.393 0.606 0.001
E44.1 Mild protein-energy malnutrition
0.392 0.607 0.000
E44.0 Moderate protein-energy malnutrition
0.392 0.607 0.000
E26.9 Hyperaldosteronism, unspecified
0.377 0.622 0.000
E26.8 Other hyperaldosteronism
0.377 0.622 0.000
E26.1 Secondary hyperaldosteronism
0.377 0.622 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.363 0.637 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.359 0.641 0.000
E22.8 Other hyperfunction of pituitary gland
0.359 0.641 0.000
E28.9 Ovarian dysfunction, unspecified
0.358 0.642 0.000
E28.8 Other ovarian dysfunction
0.358 0.642 0.000
E28.1 Androgen excess
0.358 0.642 0.000
E28.0 Oestrogen excess
0.358 0.642 0.000
E06.5 Other chronic thyroiditis
0.353 0.647 0.000
E28.3 Primary ovarian failure
0.348 0.652 0.000
E06.4 Drug-induced thyroiditis
0.338 0.662 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.338 0.662 0.000
E06.1 Subacute thyroiditis
0.338 0.662 0.000
E06.0 Acute thyroiditis
0.338 0.662 0.000
E22.1 Hyperprolactinaemia
0.330 0.669 0.000
E21.4 Other specified disorders of parathyroid gland
0.330 0.669 0.000
E50-E64 Other nutritional deficiencies
0.324 0.675 0.000
E06.9 Thyroiditis, unspecified
0.301 0.699 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.002 0.702 0.296
E83.8 Other disorders of mineral metabolism
0.002 0.702 0.296
E83.2 Disorders of zinc metabolism
0.002 0.702 0.296
E83.0 Disorders of copper metabolism
0.002 0.702 0.296
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.282 0.718 0.000
E21.3 Hyperparathyroidism, unspecified
0.277 0.723 0.000
E65-E68 Obesity and other hyperalimentation
0.275 0.724 0.001
E21.2 Other hyperparathyroidism
0.268 0.732 0.000
E54 Ascorbic acid deficiency
0.241 0.759 0.000
E56 Other vitamin deficiencies
0.233 0.766 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.233 0.767 0.000
E63 Other nutritional deficiencies
0.233 0.767 0.000
E50 Vitamin A deficiency
0.233 0.767 0.000
E60 Dietary zinc deficiency
0.233 0.767 0.000
E59 Dietary selenium deficiency
0.233 0.767 0.000
E52 Niacin deficiency [pellagra]
0.233 0.767 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.229 0.770 0.000
E51 Thiamine deficiency
0.220 0.780 0.000
E22.0 Acromegaly and pituitary gigantism
0.216 0.784 0.000
E26.0 Primary hyperaldosteronism
0.213 0.786 0.001
E61 Deficiency of other nutrient elements
0.202 0.798 0.000
E58 Dietary calcium deficiency
0.201 0.799 0.000
E67 Other hyperalimentation
0.197 0.802 0.001
E68 Sequelae of hyperalimentation
0.197 0.802 0.001
E83.4 Disorders of magnesium metabolism
0.001 0.812 0.187
E28.2 Polycystic ovarian syndrome
0.187 0.812 0.000
E53 Deficiency of other B group vitamins
0.186 0.814 0.000
E21.0 Primary hyperparathyroidism
0.184 0.816 0.000
E04 Other non-toxic goitre
0.179 0.821 0.000
E56.1 Deficiency of vitamin K
0.168 0.832 0.000
E56.9 Vitamin deficiency, unspecified
0.167 0.832 0.000
E56.8 Deficiency of other vitamins
0.167 0.832 0.000
E56.0 Deficiency of vitamin E
0.167 0.832 0.000
E50.9 Vitamin A deficiency, unspecified
0.167 0.833 0.000
E50.8 Other manifestations of vitamin A deficiency
0.167 0.833 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.167 0.833 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.167 0.833 0.000
E50.5 Vitamin A deficiency with night blindness
0.167 0.833 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.167 0.833 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.167 0.833 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.167 0.833 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.167 0.833 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.167 0.833 0.000
E63.9 Nutritional deficiency, unspecified
0.167 0.833 0.000
E63.8 Other specified nutritional deficiencies
0.167 0.833 0.000
E63.1 Imbalance of constituents of food intake
0.167 0.833 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.167 0.833 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.167 0.833 0.000
E64.8 Sequelae of other nutritional deficiencies
0.167 0.833 0.000
E64.3 Sequelae of rickets
0.167 0.833 0.000
E64.2 Sequelae of vitamin C deficiency
0.167 0.833 0.000
E64.1 Sequelae of vitamin A deficiency
0.167 0.833 0.000
E64.0 Sequelae of protein-energy malnutrition
0.167 0.833 0.000
E51.9 Thiamine deficiency, unspecified
0.158 0.842 0.000
E51.8 Other manifestations of thiamine deficiency
0.158 0.842 0.000
E51.1 Beriberi
0.158 0.842 0.000
E61.2 Magnesium deficiency
0.154 0.846 0.000
E55 Vitamin D deficiency
0.150 0.850 0.000
E51.2 Wernicke's encephalopathy
0.145 0.855 0.000
E61.9 Deficiency of nutrient element, unspecified
0.145 0.855 0.000
E61.8 Deficiency of other specified nutrient elements
0.145 0.855 0.000
E61.7 Deficiency of multiple nutrient elements
0.145 0.855 0.000
E61.6 Vanadium deficiency
0.145 0.855 0.000
E61.5 Molybdenum deficiency
0.145 0.855 0.000
E61.4 Chromium deficiency
0.145 0.855 0.000
E61.3 Manganese deficiency
0.145 0.855 0.000
E61.0 Copper deficiency
0.145 0.855 0.000
E67.8 Other specified hyperalimentation
0.142 0.858 0.001
E67.3 Hypervitaminosis D
0.142 0.858 0.001
E67.2 Megavitamin-B6 syndrome
0.142 0.858 0.001
E67.1 Hypercarotenaemia
0.142 0.858 0.001
E67.0 Hypervitaminosis A
0.142 0.858 0.001
E06.3 Autoimmune thyroiditis
0.141 0.858 0.001
E07.9 Disorder of thyroid, unspecified
0.136 0.864 0.000
E53.1 Pyridoxine deficiency
0.134 0.866 0.000
E53.0 Riboflavin deficiency
0.134 0.866 0.000
E04.0 Non-toxic diffuse goitre
0.132 0.868 0.000
E04.8 Other specified non-toxic goitre
0.128 0.872 0.000
E53.9 Vitamin B deficiency, unspecified
0.128 0.872 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.880 0.120
E65 Localised adiposity
0.119 0.880 0.001
E55.0 Rickets, active
0.108 0.892 0.000
E61.1 Iron deficiency
0.098 0.901 0.000
E53.8 Deficiency of other specified B group vitamins
0.098 0.902 0.000
K51 Ulcerative colitis
0.000 0.908 0.092
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.916 0.084
K51.2 Ulcerative (chronic) proctitis
0.000 0.916 0.084
E04.1 Non-toxic single thyroid nodule
0.080 0.920 0.000
K51.4 Pseudopolyposis of colon
0.000 0.923 0.077
E04.9 Non-toxic goitre, unspecified
0.077 0.923 0.000
M17.9 Gonarthrosis, unspecified
0.074 0.926 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.930 0.070
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.939 0.061
K51.5 Mucosal proctocolitis
0.000 0.941 0.058
L53.9 Erythematous condition, unspecified
0.044 0.956 0.000
K90-K93 Other diseases of the digestive system
0.042 0.958 0.000
E70-E90 Metabolic disorders
0.033 0.963 0.005
M20.5 Other deformities of toe(s) (acquired)
0.000 0.964 0.036
L53 Other erythematous conditions
0.034 0.966 0.000
E84 Cystic fibrosis
0.030 0.967 0.002
K93 Disorders of other digestive organs in diseases classified elsewhere
0.030 0.970 0.000
L53.0 Toxic erythema
0.029 0.971 0.000
E84.9 Cystic fibrosis, unspecified
0.028 0.971 0.001
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.025 0.971 0.003
E73 Lactose intolerance
0.025 0.972 0.003
L53.8 Other specified erythematous conditions
0.027 0.973 0.000
E70 Disorders of aromatic amino-acid metabolism
0.024 0.973 0.003
E74 Other disorders of carbohydrate metabolism
0.024 0.973 0.003
E77 Disorders of glycoprotein metabolism
0.023 0.973 0.004
E76 Disorders of glycosaminoglycan metabolism
0.023 0.973 0.004
E72 Other disorders of amino-acid metabolism
0.023 0.973 0.004
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.023 0.973 0.004
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.023 0.973 0.004
E88 Other metabolic disorders
0.025 0.974 0.002
E84.0 Cystic fibrosis with pulmonary manifestations
0.025 0.974 0.001
E83.5 Disorders of calcium metabolism
0.002 0.974 0.024
E55.9 Vitamin D deficiency, unspecified
0.025 0.975 0.001
Z46.6 Fitting and adjustment of urinary device
0.000 0.975 0.025
L53.3 Other chronic figurate erythema
0.025 0.975 0.000
L53.2 Erythema marginatum
0.025 0.975 0.000
L53.1 Erythema annulare centrifugum
0.025 0.975 0.000
K51.8 Other ulcerative colitis
0.000 0.975 0.024
E79 Disorders of purine and pyrimidine metabolism
0.020 0.976 0.004
E84.8 Cystic fibrosis with other manifestations
0.022 0.976 0.002
E84.1 Cystic fibrosis with intestinal manifestations
0.022 0.976 0.002
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.977 0.023
E88.9 Metabolic disorder, unspecified
0.022 0.977 0.001
E75.5 Other lipid storage disorders
0.020 0.978 0.002
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.022 0.978 0.000
K93.1 Megacolon in Chagas' disease
0.022 0.978 0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.022 0.978 0.000
E75.6 Lipid storage disorder, unspecified
0.018 0.979 0.002
E75.4 Neuronal ceroid lipofuscinosis
0.018 0.979 0.002
E75.3 Sphingolipidosis, unspecified
0.018 0.979 0.002
E75.2 Other sphingolipidosis
0.018 0.979 0.002
E75.1 Other gangliosidosis
0.018 0.979 0.002
E75.0 GM2 gangliosidosis
0.018 0.979 0.002
E73.9 Lactose intolerance, unspecified
0.019 0.980 0.001
E73.8 Other lactose intolerance
0.018 0.980 0.002
E73.1 Secondary lactase deficiency
0.018 0.980 0.002
E73.0 Congenital lactase deficiency
0.018 0.980 0.002
E70.3 Albinism
0.018 0.980 0.002
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.017 0.980 0.003
E70.8 Other disorders of aromatic amino-acid metabolism
0.017 0.980 0.003
E70.2 Disorders of tyrosine metabolism
0.017 0.980 0.003
E70.1 Other hyperphenylalaninaemias
0.017 0.980 0.003
E70.0 Classical phenylketonuria
0.017 0.980 0.003
E71.3 Disorders of fatty-acid metabolism
0.017 0.980 0.003
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.017 0.980 0.003
E71.1 Other disorders of branched-chain amino-acid metabolism
0.017 0.980 0.003
E71.0 Maple-syrup-urine disease
0.017 0.980 0.003
E72.9 Disorder of amino-acid metabolism, unspecified
0.017 0.980 0.003
E72.8 Other specified disorders of amino-acid metabolism
0.017 0.980 0.003
E72.5 Disorders of glycine metabolism
0.017 0.980 0.003
E72.4 Disorders of ornithine metabolism
0.017 0.980 0.003
E72.3 Disorders of lysine and hydroxylysine metabolism
0.017 0.980 0.003
E72.2 Disorders of urea cycle metabolism
0.017 0.980 0.003
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.017 0.980 0.003
E72.0 Disorders of amino-acid transport
0.017 0.980 0.003
E74.9 Disorder of carbohydrate metabolism, unspecified
0.017 0.980 0.002
E74.8 Other specified disorders of carbohydrate metabolism
0.017 0.980 0.002
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.017 0.980 0.002
E74.2 Disorders of galactose metabolism
0.017 0.980 0.002
E74.1 Disorders of fructose metabolism
0.017 0.980 0.002
E74.0 Glycogen storage disease
0.017 0.980 0.002
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.017 0.980 0.003
E76.8 Other disorders of glucosaminoglycan metabolism
0.017 0.980 0.003
E76.3 Mucopolysaccharidosis, unspecified
0.017 0.980 0.003
E76.2 Other mucopolysaccharidoses
0.017 0.980 0.003
E76.1 Mucopolysaccharidosis, type II
0.017 0.980 0.003
E76.0 Mucopolysaccharidosis, type I
0.017 0.980 0.003
E77.9 Disorder of glycoprotein metabolism, unspecified
0.017 0.980 0.003
E77.8 Other disorders of glycoprotein metabolism
0.017 0.980 0.003
E77.1 Defects in glycoprotein degradation
0.017 0.980 0.003
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.017 0.980 0.003
E74.3 Other disorders of intestinal carbohydrate absorption
0.018 0.980 0.002
E88.2 Lipomatosis, not elsewhere classified
0.018 0.981 0.001
M20.1 Hallux valgus (acquired)
0.000 0.981 0.019
C19 Malignant neoplasm of rectosigmoid junction
0.018 0.982 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.017 0.982 0.001
E88.3 Tumour lysis syndrome
0.016 0.982 0.001
E88.8 Other specified metabolic disorders
0.016 0.982 0.001
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.017 0.982 0.001
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.014 0.982 0.003
E79.8 Other disorders of purine and pyrimidine metabolism
0.014 0.982 0.003
E79.1 Lesch-Nyhan syndrome
0.014 0.982 0.003
E80 Disorders of porphyrin and bilirubin metabolism
0.013 0.983 0.004
E04.2 Non-toxic multinodular goitre
0.017 0.983 0.000
E66 Obesity
0.016 0.983 0.001
L50-L54 Urticaria and erythema
0.016 0.983 0.000
E11 Non-insulin-dependent diabetes mellitus
0.016 0.984 0.000
M20 Acquired deformities of fingers and toes
0.000 0.984 0.016
E85 Amyloidosis
0.011 0.985 0.005
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.011 0.986 0.004
E86 Volume depletion
0.014 0.986 0.000
L52 Erythema nodosum
0.014 0.986 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.014 0.986 0.000
E11.1 With ketoacidosis
0.013 0.987 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.010 0.988 0.003
E80.5 Crigler-Najjar syndrome
0.010 0.988 0.003
E80.3 Defects of catalase and peroxydase
0.010 0.988 0.003
E80.0 Hereditary erythropoietic porphyria
0.010 0.988 0.003
I69.3 Sequelae of cerebral infarction
0.000 0.988 0.012
L50.0 Allergic urticaria
0.012 0.988 0.000
E66.1 Drug-induced obesity
0.012 0.988 0.001
E80.6 Other disorders of bilirubin metabolism
0.010 0.988 0.002
E80.2 Other porphyria
0.010 0.988 0.003
L50 Urticaria
0.012 0.988 0.000
L54 Erythema in diseases classified elsewhere
0.012 0.988 0.000
E78.6 Lipoprotein deficiency
0.012 0.988 0.000
E11.7 With multiple complications
0.012 0.988 0.000
M20.4 Other hammer toe(s) (acquired)
0.000 0.988 0.012
K50-K52 Noninfective enteritis and colitis
0.000 0.988 0.012
E80.1 Porphyria cutanea tarda
0.009 0.988 0.003
E78.1 Pure hyperglyceridaemia
0.011 0.989 0.000
E85.8 Other amyloidosis
0.008 0.989 0.004
E85.2 Heredofamilial amyloidosis, unspecified
0.008 0.989 0.004
E85.1 Neuropathic heredofamilial amyloidosis
0.008 0.989 0.004
E85.0 Nonneuropathic heredofamilial amyloidosis
0.008 0.989 0.004
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.009 0.989 0.002
E11.0 With coma
0.010 0.989 0.000
E11.6 With other specified complications
0.010 0.990 0.000
L51 Erythema multiforme
0.010 0.990 0.000
E85.3 Secondary systemic amyloidosis
0.006 0.990 0.004
E78.3 Hyperchylomicronaemia
0.010 0.990 0.000
E78.8 Other disorders of lipoprotein metabolism
0.010 0.990 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.990 0.010
E78.4 Other hyperlipidaemia
0.009 0.990 0.000
E85.4 Organ-limited amyloidosis
0.005 0.991 0.004
E85.9 Amyloidosis, unspecified
0.005 0.991 0.005
E78.9 Disorder of lipoprotein metabolism, unspecified
0.009 0.991 0.000
L50.6 Contact urticaria
0.009 0.991 0.000
L50.5 Cholinergic urticaria
0.009 0.991 0.000
L50.4 Vibratory urticaria
0.009 0.991 0.000
L50.3 Dermatographic urticaria
0.009 0.991 0.000
L50.2 Urticaria due to cold and heat
0.009 0.991 0.000
L54.8 Erythema in other diseases classified elsewhere
0.009 0.991 0.000
L54.0 Erythema marginatum in acute rheumatic fever
0.009 0.991 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.008 0.991 0.001
D12.0 Caecum
0.000 0.991 0.009
E78.2 Mixed hyperlipidaemia
0.009 0.991 0.000
E11.2 With renal complications
0.009 0.991 0.000
E89.4 Postprocedural ovarian failure
0.007 0.991 0.001
M20.3 Other deformity of hallux (acquired)
0.000 0.992 0.008
E11.8 With unspecified complications
0.008 0.992 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.008 0.992 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.006 0.992 0.002
E89.8 Other postprocedural endocrine and metabolic disorders
0.006 0.992 0.002
E89.5 Postprocedural testicular hypofunction
0.006 0.992 0.002
E89.1 Postprocedural hypoinsulinaemia
0.006 0.992 0.002
N50.8 Other specified disorders of male genital organs
0.008 0.992 0.000
E66.0 Obesity due to excess calories
0.007 0.992 0.001
L40.9 Psoriasis, unspecified
0.008 0.992 0.000
I42.9 Cardiomyopathy, unspecified
0.000 0.992 0.008
L50.1 Idiopathic urticaria
0.008 0.992 0.000
I83 Varicose veins of lower extremities
0.000 0.992 0.008
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.006 0.992 0.002
L51.8 Other erythema multiforme
0.007 0.992 0.000
L51.2 Toxic epidermal necrolysis [Lyell]
0.007 0.992 0.000
L51.0 Nonbullous erythema multiforme
0.007 0.992 0.000
E78.5 Hyperlipidaemia, unspecified
0.007 0.993 0.000
L51.9 Erythema multiforme, unspecified
0.007 0.993 0.000
L40 Psoriasis
0.007 0.993 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.993 0.007
E89.3 Postprocedural hypopituitarism
0.005 0.993 0.002
L51.1 Bullous erythema multiforme
0.006 0.993 0.000
K50 Crohn's disease [regional enteritis]
0.000 0.993 0.007
E11.5 With peripheral circulatory complications
0.006 0.994 0.000
L50.9 Urticaria, unspecified
0.006 0.994 0.000
S02.4 Fracture of malar and maxillary bones
0.006 0.994 0.000
L40.3 Pustulosis palmaris et plantaris
0.006 0.994 0.000
L40.0 Psoriasis vulgaris
0.006 0.994 0.000
S20.2 Contusion of thorax
0.006 0.994 0.000
L40.4 Guttate psoriasis
0.006 0.994 0.000
S92.30 Fracture of metatarsal bone (closed)
0.006 0.994 0.000
L50.8 Other urticaria
0.005 0.994 0.001
E89.2 Postprocedural hypoparathyroidism
0.004 0.994 0.002
K75.4 Autoimmune hepatitis
0.006 0.994 0.000
E80.4 Gilbert's syndrome
0.003 0.994 0.003
T39.1 4-Aminophenol derivatives
0.000 0.994 0.006
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.994 0.006
R30-R39 Symptoms and signs involving the urinary system
0.000 0.994 0.006
L40.1 Generalised pustular psoriasis
0.005 0.994 0.000
L40.2 Acrodermatitis continua
0.005 0.995 0.000
L43.9 Lichen planus, unspecified
0.005 0.995 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.995 0.005
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.005 0.995 0.000
K50.1 Crohn's disease of large intestine
0.000 0.995 0.005
L40.5 Arthropathic psoriasis
0.005 0.995 0.000
L40-L45 Papulosquamous disorders
0.005 0.995 0.000
T42.4 Benzodiazepines
0.000 0.995 0.005
M20.0 Deformity of finger(s)
0.000 0.995 0.005
S20 Superficial injury of thorax
0.005 0.995 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.995 0.005
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.995 0.005
S05.1 Contusion of eyeball and orbital tissues
0.005 0.995 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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