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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16914589
log Bayes Factor = 19.9553
Chromosome 11   position 49,974,670  (GRCh37) Explore rs16914589 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.999 0.001 0.000
I25.2 Old myocardial infarction
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
I20.9 Angina pectoris, unspecified
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.997 0.003 0.000
Chapter I Certain infectious and parasitic diseases
0.997 0.003 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.996 0.004 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.995 0.005 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.993 0.007 0.000
I20.0 Unstable angina
0.993 0.007 0.000
R06 Abnormalities of breathing
0.993 0.007 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.993 0.007 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.991 0.009 0.000
R05 Cough
0.989 0.011 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.989 0.011 0.000
T51 Toxic effect of alcohol
0.988 0.012 0.000
T51.0 Ethanol
0.985 0.015 0.000
R06.0 Dyspnoea
0.984 0.016 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.983 0.017 0.000
I25.1 Atherosclerotic heart disease
0.981 0.019 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.981 0.019 0.000
B25-B34 Other viral diseases
0.980 0.020 0.000
I21 Acute myocardial infarction
0.973 0.027 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.969 0.031 0.000
I21.9 Acute myocardial infarction, unspecified
0.969 0.031 0.000
B34 Viral infection of unspecified site
0.969 0.031 0.000
J45 Asthma
0.968 0.032 0.000
J95-J99 Other diseases of the respiratory system
0.967 0.033 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.966 0.034 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.964 0.036 0.000
Chapter V Mental and behavioural disorders
0.962 0.038 0.000
B34.9 Viral infection, unspecified
0.961 0.039 0.000
Y85 Sequelae of transport accidents
0.959 0.041 0.000
S50-S59 Injuries to the elbow and forearm
0.951 0.049 0.000
T39.0 Salicylates
0.947 0.053 0.000
J45.9 Asthma, unspecified
0.946 0.054 0.000
B07 Viral warts
0.942 0.058 0.000
J98 Other respiratory disorders
0.941 0.059 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.937 0.063 0.000
F60-F69 Disorders of adult personality and behaviour
0.935 0.065 0.000
Y85.0 Sequelae of motor-vehicle accident
0.933 0.067 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.929 0.071 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.925 0.075 0.000
T93 Sequelae of injuries of lower limb
0.924 0.076 0.000
T66-T78 Other and unspecified effects of external causes
0.924 0.076 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.924 0.076 0.000
X60-X84 Intentional self-harm
0.923 0.077 0.000
E78.0 Pure hypercholesterolaemia
0.922 0.078 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.920 0.080 0.000
E78.5 Hyperlipidaemia, unspecified
0.919 0.081 0.000
E70-E90 Metabolic disorders
0.919 0.081 0.000
R07 Pain in throat and chest
0.917 0.083 0.000
J40 Bronchitis, not specified as acute or chronic
0.916 0.084 0.000
F41 Other anxiety disorders
0.915 0.085 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.914 0.086 0.000
F41.9 Anxiety disorder, unspecified
0.914 0.086 0.000
F60 Specific personality disorders
0.913 0.087 0.000
R06.2 Wheezing
0.906 0.094 0.000
S90-S99 Injuries to the ankle and foot
0.903 0.097 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.899 0.101 0.000
R06.1 Stridor
0.895 0.105 0.000
J09-J18 Influenza and pneumonia
0.894 0.106 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.891 0.109 0.000
B00 Herpesviral [herpes simplex] infections
0.891 0.109 0.000
I73 Other peripheral vascular diseases
0.885 0.115 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.881 0.119 0.000
I10-I15 Hypertensive diseases
0.880 0.120 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.877 0.123 0.000
Y86 Sequelae of other accidents
0.873 0.127 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.870 0.130 0.000
J98.9 Respiratory disorder, unspecified
0.868 0.132 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.863 0.137 0.000
B02 Zoster [herpes zoster]
0.860 0.140 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.859 0.141 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.857 0.143 0.000
R07.2 Precordial pain
0.855 0.145 0.000
S51 Open wound of forearm
0.854 0.146 0.000
W00-W19 Falls
0.852 0.148 0.000
I10 Essential (primary) hypertension
0.842 0.158 0.000
F60.3 Emotionally unstable personality disorder
0.840 0.159 0.000
R03.1 Nonspecific low blood-pressure reading
0.838 0.162 0.000
W20-W49 Exposure to inanimate mechanical forces
0.834 0.166 0.000
J84 Other interstitial pulmonary diseases
0.833 0.167 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.833 0.167 0.000
I71 Aortic aneurysm and dissection
0.832 0.168 0.000
T78 Adverse effects, not elsewhere classified
0.830 0.170 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.830 0.170 0.000
I73.9 Peripheral vascular disease, unspecified
0.828 0.172 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.825 0.175 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.820 0.180 0.000
S56 Injury of muscle and tendon at forearm level
0.820 0.180 0.000
X10-X19 Contact with heat and hot substances
0.820 0.180 0.000
R07.0 Pain in throat
0.819 0.181 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.818 0.182 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.814 0.186 0.000
R94 Abnormal results of function studies
0.812 0.188 0.000
T59 Toxic effect of other gases, fumes and vapours
0.811 0.189 0.000
I78 Diseases of capillaries
0.811 0.189 0.000
B35-B49 Mycoses
0.810 0.190 0.000
T63 Toxic effect of contact with venomous animals
0.810 0.190 0.000
S92 Fracture of foot, except ankle
0.807 0.193 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.806 0.194 0.000
E78.2 Mixed hyperlipidaemia
0.800 0.200 0.000
S50 Superficial injury of forearm
0.800 0.200 0.000
J98.6 Disorders of diaphragm
0.800 0.200 0.000
F60.9 Personality disorder, unspecified
0.800 0.200 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.799 0.201 0.000
T17 Foreign body in respiratory tract
0.798 0.202 0.000
B27 Infectious mononucleosis
0.795 0.205 0.000
B02.3 Zoster ocular disease
0.794 0.206 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.792 0.207 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.790 0.210 0.000
W50-W64 Exposure to animate mechanical forces
0.789 0.211 0.000
J98.8 Other specified respiratory disorders
0.787 0.213 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.786 0.214 0.000
R25 Abnormal involuntary movements
0.785 0.215 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.784 0.216 0.000
S54 Injury of nerves at forearm level
0.782 0.218 0.000
T92 Sequelae of injuries of upper limb
0.781 0.219 0.000
T40.2 Other opioids
0.780 0.220 0.000
S51.0 Open wound of elbow
0.779 0.221 0.000
I74 Arterial embolism and thrombosis
0.779 0.221 0.000
B00.0 Eczema herpeticum
0.778 0.222 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.777 0.223 0.000
I23 Certain current complications following acute myocardial infarction
0.774 0.226 0.000
T93.0 Sequelae of open wound of lower limb
0.774 0.226 0.000
J17 Pneumonia in diseases classified elsewhere
0.771 0.229 0.000
I20.1 Angina pectoris with documented spasm
0.770 0.230 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.767 0.233 0.000
I72 Other aneurysm
0.766 0.234 0.000
X20-X29 Contact with venomous animals and plants
0.764 0.236 0.000
R25.1 Tremor, unspecified
0.764 0.236 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.764 0.236 0.000
B15-B19 Viral hepatitis
0.763 0.237 0.000
Y89 Sequelae of other external causes
0.761 0.238 0.000
D80-D89 Certain disorders involving the immune mechanism
0.760 0.240 0.000
T91 Sequelae of injuries of neck and trunk
0.760 0.240 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.759 0.241 0.000
B00.9 Herpesviral infection, unspecified
0.757 0.243 0.000
B01 Varicella [chickenpox]
0.756 0.243 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.755 0.244 0.000
X65 Intentional self-poisoning by and exposure to alcohol
0.755 0.245 0.000
I25.4 Coronary artery aneurysm
0.755 0.245 0.000
T78.2 Anaphylactic shock, unspecified
0.755 0.245 0.000
R07.4 Chest pain, unspecified
0.755 0.245 0.000
X62.9 Unspecified place
0.755 0.245 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.754 0.246 0.000
W17 Other fall from one level to another
0.754 0.246 0.000
S92.3 Fracture of metatarsal bone
0.753 0.247 0.000
R94.5 Abnormal results of liver function studies
0.752 0.248 0.000
F60.0 Paranoid personality disorder
0.751 0.249 0.000
A65-A69 Other spirochaetal diseases
0.751 0.249 0.000
Y10-Y34 Event of undetermined intent
0.750 0.250 0.000
T93.2 Sequelae of other fractures of lower limb
0.747 0.253 0.000
I21.4 Acute subendocardial myocardial infarction
0.747 0.253 0.000
D86 Sarcoidosis
0.745 0.255 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.745 0.255 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.745 0.255 0.000
J98.2 Interstitial emphysema
0.739 0.261 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.738 0.262 0.000
T40.4 Other synthetic narcotics
0.737 0.263 0.000
B50-B64 Protozoal diseases
0.735 0.265 0.000
F41.3 Other mixed anxiety disorders
0.735 0.265 0.000
D86.9 Sarcoidosis, unspecified
0.735 0.265 0.000
T00-T07 Injuries involving multiple body regions
0.734 0.266 0.000
R06.8 Other and unspecified abnormalities of breathing
0.730 0.270 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.730 0.270 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.729 0.271 0.000
B99-B99 Other infectious diseases
0.728 0.272 0.000
I22 Subsequent myocardial infarction
0.727 0.273 0.000
E40-E46 Malnutrition
0.726 0.274 0.000
V98-V99 Other and unspecified transport accidents
0.725 0.274 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.725 0.275 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.725 0.275 0.000
X45 Accidental poisoning by and exposure to alcohol
0.724 0.276 0.000
A80-A89 Viral infections of the central nervous system
0.724 0.276 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.723 0.277 0.000
T23 Burn and corrosion of wrist and hand
0.721 0.279 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.721 0.279 0.000
S99 Other and unspecified injuries of ankle and foot
0.718 0.282 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.717 0.283 0.000
J10 Influenza due to identified influenza virus
0.717 0.283 0.000
T42.0 Hydantoin derivatives
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.715 0.285 0.000
T75 Effects of other external causes
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
S92.30 Fracture of metatarsal bone (closed)
0.714 0.286 0.000
J14 Pneumonia due to Haemophilus influenzae
0.713 0.287 0.000
T65 Toxic effect of other and unspecified substances
0.713 0.287 0.000
T62 Toxic effect of other noxious substances eaten as food
0.713 0.287 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.713 0.287 0.000
T60 Toxic effect of pesticides
0.713 0.287 0.000
T57 Toxic effect of other inorganic substances
0.713 0.287 0.000
T56 Toxic effect of metals
0.713 0.287 0.000
T54 Toxic effect of corrosive substances
0.713 0.287 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.713 0.287 0.000
T52 Toxic effect of organic solvents
0.713 0.287 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.713 0.287 0.000
T55 Toxic effect of soaps and detergents
0.713 0.287 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.713 0.287 0.000
T39.1 4-Aminophenol derivatives
0.712 0.288 0.000
R06.7 Sneezing
0.712 0.288 0.000
R06.3 Periodic breathing
0.712 0.288 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.712 0.288 0.000
J00-J06 Acute upper respiratory infections
0.711 0.289 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.711 0.289 0.000
T39.4 Antirheumatics, not elsewhere classified
0.711 0.289 0.000
T39.2 Pyrazolone derivatives
0.711 0.289 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.710 0.290 0.000
J60-J70 Lung diseases due to external agents
0.710 0.290 0.000
T36 Poisoning by systemic antibiotics
0.710 0.290 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.709 0.291 0.000
B06 Rubella [German measles]
0.709 0.291 0.000
B05 Measles
0.709 0.291 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.709 0.291 0.000
B04 Monkeypox
0.709 0.291 0.000
B03 Smallpox
0.709 0.291 0.000
Chapter XXII Codes for special purposes
0.709 0.291 0.000
T51.8 Other alcohols
0.709 0.291 0.000
T51.3 Fusel oil
0.709 0.291 0.000
T51.2 2-Propanol
0.709 0.291 0.000
T51.1 Methanol
0.709 0.291 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.708 0.292 0.000
F60.7 Dependent personality disorder
0.707 0.293 0.000
V40-V49 Car occupant injured in transport accident
0.706 0.294 0.000
I25.5 Ischaemic cardiomyopathy
0.706 0.294 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.705 0.295 0.000
T79-T79 Certain early complications of trauma
0.705 0.295 0.000
T66 Unspecified effects of radiation
0.705 0.295 0.000
W13 Fall from, out of or through building or structure
0.705 0.295 0.000
F69 Unspecified disorder of adult personality and behaviour
0.704 0.296 0.000
B33 Other viral diseases, not elsewhere classified
0.703 0.297 0.000
B30 Viral conjunctivitis
0.703 0.297 0.000
B26 Mumps
0.703 0.297 0.000
R06.6 Hiccough
0.702 0.298 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.701 0.299 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.701 0.299 0.000
T17.9 Foreign body in respiratory tract, part unspecified
0.700 0.300 0.000
S10-S19 Injuries to the neck
0.700 0.300 0.000
T68 Hypothermia
0.699 0.300 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.699 0.301 0.000
F44 Dissociative [conversion] disorders
0.699 0.301 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.698 0.301 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.698 0.302 0.000
S80-S89 Injuries to the knee and lower leg
0.697 0.303 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.697 0.303 0.000
E86 Volume depletion
0.696 0.304 0.000
B34.4 Papovirus infection, unspecified
0.694 0.305 0.000
B34.3 Parvovirus infection, unspecified
0.694 0.305 0.000
B34.2 Coronavirus infection, unspecified
0.694 0.305 0.000
B34.1 Enterovirus infection, unspecified
0.694 0.305 0.000
B34.0 Adenovirus infection, unspecified
0.694 0.305 0.000
J45.8 Mixed asthma
0.694 0.306 0.000
J45.1 Nonallergic asthma
0.694 0.306 0.000
J96 Respiratory failure, not elsewhere classified
0.694 0.306 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.692 0.307 0.000
R27 Other lack of coordination
0.692 0.308 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.692 0.308 0.000
W44 Foreign body entering into or through eye or natural orifice
0.692 0.308 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.691 0.308 0.000
T95 Sequelae of burns, corrosions and frostbite
0.691 0.309 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.691 0.309 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.691 0.309 0.000
E88 Other metabolic disorders
0.690 0.310 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.689 0.311 0.000
R82 Other abnormal findings in urine
0.689 0.311 0.000
F80-F89 Disorders of psychological development
0.687 0.312 0.000
I74.5 Embolism and thrombosis of iliac artery
0.687 0.313 0.000
J81 Pulmonary oedema
0.687 0.313 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.687 0.313 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.686 0.314 0.000
E78.1 Pure hyperglyceridaemia
0.686 0.314 0.000
Y00-Y09 Assault
0.684 0.316 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.684 0.316 0.000
I25.3 Aneurysm of heart
0.683 0.316 0.000
I78.1 Naevus, nonneoplastic
0.683 0.317 0.000
B34.8 Other viral infections of unspecified site
0.683 0.317 0.000
J45.0 Predominantly allergic asthma
0.682 0.318 0.000
S59 Other and unspecified injuries of forearm
0.682 0.318 0.000
S58 Traumatic amputation of forearm
0.682 0.318 0.000
S57 Crushing injury of forearm
0.682 0.318 0.000
S55 Injury of blood vessels at forearm level
0.682 0.318 0.000
R94.4 Abnormal results of kidney function studies
0.682 0.318 0.000
B02.9 Zoster without complication
0.681 0.319 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.681 0.319 0.000
W11 Fall on and from ladder
0.681 0.319 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.680 0.320 0.000
V80-V89 Other land transport accidents
0.679 0.321 0.000
F70-F79 Mental retardation
0.679 0.321 0.000
I70 Atherosclerosis
0.678 0.322 0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.678 0.322 0.000
T63.4 Venom of other arthropods
0.677 0.323 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.676 0.324 0.000
V20-V29 Motorcycle rider injured in transport accident
0.675 0.325 0.000
J98.3 Compensatory emphysema
0.675 0.325 0.000
J84.8 Other specified interstitial pulmonary diseases
0.674 0.326 0.000
J98.4 Other disorders of lung
0.674 0.326 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.672 0.328 0.000
A30-A49 Other bacterial diseases
0.672 0.328 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.671 0.329 0.000
F68 Other disorders of adult personality and behaviour
0.670 0.330 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.670 0.330 0.000
F65 Disorders of sexual preference
0.670 0.330 0.000
F64 Gender identity disorders
0.670 0.330 0.000
F63 Habit and impulse disorders
0.670 0.330 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.670 0.330 0.000
F61 Mixed and other personality disorders
0.670 0.330 0.000
B37 Candidiasis
0.670 0.330 0.000
S51.8 Open wound of other parts of forearm
0.669 0.331 0.000
I73.0 Raynaud's syndrome
0.668 0.332 0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.667 0.333 0.000
S50.9 Superficial injury of forearm, unspecified
0.667 0.333 0.000
E78.6 Lipoprotein deficiency
0.666 0.334 0.000
E78.3 Hyperchylomicronaemia
0.666 0.334 0.000
E50-E64 Other nutritional deficiencies
0.666 0.334 0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level
0.664 0.335 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.664 0.336 0.000
X16 Contact with hot heating appliances, radiators and pipes
0.664 0.336 0.000
T59.9 Gases, fumes and vapours, unspecified
0.663 0.337 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.663 0.337 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.663 0.337 0.000
T74 Maltreatment syndromes
0.663 0.337 0.000
T73 Effects of other deprivation
0.663 0.337 0.000
T70 Effects of air pressure and water pressure
0.663 0.337 0.000
T69 Other effects of reduced temperature
0.663 0.337 0.000
T67 Effects of heat and light
0.663 0.337 0.000
T71 Asphyxiation
0.663 0.337 0.000
B27.9 Infectious mononucleosis, unspecified
0.662 0.337 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.662 0.338 0.000
T16 Foreign body in ear
0.662 0.338 0.000
X84 Intentional self-harm by unspecified means
0.662 0.338 0.000
X83 Intentional self-harm by other specified means
0.662 0.338 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.662 0.338 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.662 0.338 0.000
X80 Intentional self-harm by jumping from a high place
0.662 0.338 0.000
X79 Intentional self-harm by blunt object
0.662 0.338 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.662 0.338 0.000
X76 Intentional self-harm by smoke, fire and flames
0.662 0.338 0.000
X75 Intentional self-harm by explosive material
0.662 0.338 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.662 0.338 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.662 0.338 0.000
X72 Intentional self-harm by handgun discharge
0.662 0.338 0.000
X71 Intentional self-harm by drowning and submersion
0.662 0.338 0.000
X70 Intentional self-harm by hanging, strangulation and suffocation
0.662 0.338 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.662 0.338 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.662 0.338 0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.662 0.338 0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.662 0.338 0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.662 0.338 0.000
S54.1 Injury of median nerve at forearm level
0.662 0.338 0.000
B00.4 Herpesviral encephalitis
0.661 0.339 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.661 0.339 0.000
F48 Other neurotic disorders
0.660 0.340 0.000
E74 Other disorders of carbohydrate metabolism
0.659 0.341 0.000
E84 Cystic fibrosis
0.659 0.341 0.000
E79 Disorders of purine and pyrimidine metabolism
0.659 0.341 0.000
E77 Disorders of glycoprotein metabolism
0.659 0.341 0.000
E76 Disorders of glycosaminoglycan metabolism
0.659 0.341 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.659 0.341 0.000
E72 Other disorders of amino-acid metabolism
0.659 0.341 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.659 0.341 0.000
E70 Disorders of aromatic amino-acid metabolism
0.659 0.341 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.659 0.341 0.000
T18 Foreign body in alimentary tract
0.659 0.341 0.000
T42.1 Iminostilbenes
0.658 0.342 0.000
S92.1 Fracture of talus
0.658 0.342 0.000
W07 Fall involving chair
0.658 0.342 0.000
S51.7 Multiple open wounds of forearm
0.657 0.343 0.000
T40.6 Other and unspecified narcotics
0.656 0.344 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.656 0.344 0.000
F41.8 Other specified anxiety disorders
0.656 0.344 0.000
V10-V19 Pedal cyclist injured in transport accident
0.655 0.345 0.000
F60.8 Other specific personality disorders
0.654 0.345 0.000
F60.6 Anxious [avoidant] personality disorder
0.654 0.345 0.000
F60.5 Anankastic personality disorder
0.654 0.345 0.000
F60.4 Histrionic personality disorder
0.654 0.345 0.000
F60.2 Dissocial personality disorder
0.654 0.345 0.000
F60.1 Schizoid personality disorder
0.654 0.345 0.000
W20 Struck by thrown, projected or falling object
0.654 0.346 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.654 0.346 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.654 0.346 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.654 0.346 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.653 0.347 0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level
0.652 0.348 0.000
F99-F99 Unspecified mental disorder
0.651 0.348 0.000
T98 Sequelae of other and unspecified effects of external causes
0.651 0.349 0.000
S91 Open wound of ankle and foot
0.650 0.350 0.000
W17.4 Street and highway
0.650 0.350 0.000
S98 Traumatic amputation of ankle and foot
0.647 0.353 0.000
S97 Crushing injury of ankle and foot
0.647 0.353 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.647 0.353 0.000
S95 Injury of blood vessels at ankle and foot level
0.647 0.353 0.000
S94 Injury of nerves at ankle and foot level
0.647 0.353 0.000
W22 Striking against or struck by other objects
0.647 0.353 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.647 0.353 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.646 0.353 0.000
J80 Adult respiratory distress syndrome
0.646 0.354 0.000
S70-S79 Injuries to the hip and thigh
0.645 0.355 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.644 0.356 0.000
T40.8 Lysergide [LSD]
0.644 0.356 0.000
T40.7 Cannabis (derivatives)
0.644 0.356 0.000
T40.5 Cocaine
0.644 0.356 0.000
T40.3 Methadone
0.644 0.356 0.000
T40.1 Heroin
0.644 0.356 0.000
T40.0 Opium
0.644 0.356 0.000
W21 Striking against or struck by sports equipment
0.644 0.356 0.000
E65-E68 Obesity and other hyperalimentation
0.641 0.359 0.000
T45.2 Vitamins, not elsewhere classified
0.641 0.359 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.641 0.359 0.000
J12 Viral pneumonia, not elsewhere classified
0.641 0.359 0.000
J09 Influenza due to certain identified influenza virus
0.641 0.359 0.000
T19 Foreign body in genito-urinary tract
0.639 0.361 0.000
T15 Foreign body on external eye
0.639 0.361 0.000
B00.8 Other forms of herpesviral infection
0.639 0.361 0.000
B00.7 Disseminated herpesviral disease
0.639 0.361 0.000
B00.5 Herpesviral ocular disease
0.639 0.361 0.000
B00.3 Herpesviral meningitis
0.639 0.361 0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis
0.639 0.361 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.638 0.361 0.000
B35 Dermatophytosis
0.637 0.363 0.000
T93.1 Sequelae of fracture of femur
0.636 0.363 0.000
T90 Sequelae of injuries of head
0.637 0.363 0.000
E73 Lactose intolerance
0.635 0.365 0.000
X65.8 Other specified place
0.635 0.365 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.634 0.366 0.000
I78.8 Other diseases of capillaries
0.632 0.367 0.000
S50.1 Contusion of other and unspecified parts of forearm
0.632 0.368 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.632 0.368 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.631 0.369 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.631 0.369 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.631 0.369 0.000
T42.3 Barbiturates
0.631 0.369 0.000
T42.2 Succinimides and oxazolidinediones
0.631 0.369 0.000
I13 Hypertensive heart and renal disease
0.631 0.369 0.000
D55-D59 Haemolytic anaemias
0.631 0.369 0.000
X12 Contact with other hot fluids
0.631 0.369 0.000
D50-D53 Nutritional anaemias
0.630 0.369 0.000
T78.4 Allergy, unspecified
0.630 0.370 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.630 0.370 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.629 0.371 0.000
T17.2 Foreign body in pharynx
0.629 0.371 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.629 0.371 0.000
X48 Accidental poisoning by and exposure to pesticides
0.629 0.371 0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.629 0.371 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.629 0.371 0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.629 0.371 0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level
0.627 0.372 0.000
E78.8 Other disorders of lipoprotein metabolism
0.627 0.373 0.000
X50-X57 Overexertion, travel and privation
0.627 0.373 0.000
R81 Glycosuria
0.627 0.373 0.000
S40-S49 Injuries to the shoulder and upper arm
0.626 0.374 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.624 0.375 0.000
T50.8 Diagnostic agents
0.624 0.376 0.000
T50.7 Analeptics and opioid receptor antagonists
0.624 0.376 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.624 0.376 0.000
T50.5 Appetite depressants
0.624 0.376 0.000
T50.4 Drugs affecting uric acid metabolism
0.624 0.376 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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