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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16967103
log Bayes Factor = 14.2899
Chromosome 15   position 38,899,190  (GRCh37) Explore rs16967103 on Ensembl!
Variant rs16967103 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
Chapter VIII Diseases of the ear and mastoid process
0.998 0.002 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.998 0.002 0.000
E10 Insulin-dependent diabetes mellitus
0.997 0.003 0.000
H65-H75 Diseases of middle ear and mastoid
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.995 0.005 0.000
E10.9 Without complications
0.993 0.007 0.000
M65-M68 Disorders of synovium and tendon
0.992 0.008 0.000
M65 Synovitis and tenosynovitis
0.990 0.010 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.990 0.010 0.000
M05-M14 Inflammatory polyarthropathies
0.989 0.011 0.000
E20-E35 Disorders of other endocrine glands
0.988 0.012 0.000
E50-E64 Other nutritional deficiencies
0.985 0.015 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.983 0.017 0.000
Y86 Sequelae of other accidents
0.982 0.018 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.980 0.020 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.980 0.020 0.000
M20-M25 Other joint disorders
0.978 0.022 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.978 0.022 0.000
Y85 Sequelae of transport accidents
0.978 0.022 0.000
E05.9 Thyrotoxicosis, unspecified
0.977 0.023 0.000
L03 Cellulitis
0.972 0.028 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.966 0.034 0.000
H71 Cholesteatoma of middle ear
0.966 0.034 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.963 0.037 0.000
M06 Other rheumatoid arthritis
0.957 0.043 0.000
L03.9 Cellulitis, unspecified
0.957 0.043 0.000
E53 Deficiency of other B group vitamins
0.956 0.044 0.000
L03.1 Cellulitis of other parts of limb
0.956 0.044 0.000
H74 Other disorders of middle ear and mastoid
0.955 0.045 0.000
E27 Other disorders of adrenal gland
0.954 0.046 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.954 0.046 0.000
M07 Psoriatic and enteropathic arthropathies
0.948 0.052 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.943 0.057 0.000
M22 Disorders of patella
0.940 0.060 0.000
E53.8 Deficiency of other specified B group vitamins
0.939 0.061 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.935 0.065 0.000
M31 Other necrotising vasculopathies
0.933 0.067 0.000
M86-M90 Other osteopathies
0.932 0.068 0.000
E29 Testicular dysfunction
0.931 0.069 0.000
H90-H95 Other disorders of ear
0.929 0.071 0.000
M06.9 Rheumatoid arthritis, unspecified
0.927 0.073 0.000
E14 Unspecified diabetes mellitus
0.920 0.080 0.000
H92 Otalgia and effusion of ear
0.919 0.081 0.000
M07.3 Other psoriatic arthropathies
0.919 0.081 0.000
E10.0 With coma
0.918 0.082 0.000
E61 Deficiency of other nutrient elements
0.916 0.084 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.913 0.087 0.000
W20-W49 Exposure to inanimate mechanical forces
0.909 0.091 0.000
H92.0 Otalgia
0.907 0.093 0.000
M40-M43 Deforming dorsopathies
0.905 0.095 0.000
H72 Perforation of tympanic membrane
0.905 0.095 0.000
Y85.0 Sequelae of motor-vehicle accident
0.898 0.102 0.000
E22 Hyperfunction of pituitary gland
0.890 0.110 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.890 0.110 0.000
E29.1 Testicular hypofunction
0.890 0.110 0.000
Q00-Q07 Congenital malformations of the nervous system
0.889 0.111 0.000
M21 Other acquired deformities of limbs
0.887 0.113 0.000
M24 Other specific joint derangements
0.886 0.114 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.884 0.116 0.000
E14.3 With ophthalmic complications
0.878 0.122 0.000
M22.4 Chondromalacia patellae
0.877 0.123 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.870 0.130 0.000
M43 Other deforming dorsopathies
0.867 0.133 0.000
E61.1 Iron deficiency
0.865 0.135 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.862 0.138 0.000
Q24 Other congenital malformations of heart
0.862 0.138 0.000
M31.3 Wegener's granulomatosis
0.854 0.146 0.000
H74.4 Polyp of middle ear
0.853 0.147 0.000
M06.4 Inflammatory polyarthropathy
0.845 0.155 0.000
E27.1 Primary adrenocortical insufficiency
0.844 0.156 0.000
H74.0 Tympanosclerosis
0.843 0.157 0.000
M05 Seropositive rheumatoid arthritis
0.842 0.158 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.841 0.159 0.000
Q23 Congenital malformations of aortic and mitral valves
0.840 0.160 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.837 0.162 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.837 0.163 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.835 0.165 0.000
M60-M63 Disorders of muscles
0.833 0.167 0.000
E10.3 With ophthalmic complications
0.832 0.168 0.000
M31.1 Thrombotic microangiopathy
0.829 0.171 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.829 0.171 0.000
M24.2 Disorder of ligament
0.828 0.172 0.000
T92 Sequelae of injuries of upper limb
0.825 0.175 0.000
Q25 Congenital malformations of great arteries
0.825 0.175 0.000
M21.1 Varus deformity, not elsewhere classified
0.822 0.177 0.000
V40-V49 Car occupant injured in transport accident
0.822 0.178 0.000
M87 Osteonecrosis
0.822 0.178 0.000
M43.1 Spondylolisthesis
0.822 0.178 0.000
Y88 Sequelae of surgical and medical care as external cause
0.819 0.181 0.000
M12 Other specific arthropathies
0.818 0.182 0.000
M30 Polyarteritis nodosa and related conditions
0.815 0.185 0.000
Y00-Y09 Assault
0.813 0.186 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.809 0.191 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.808 0.192 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.806 0.194 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.806 0.194 0.000
Q05 Spina bifida
0.803 0.197 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.801 0.199 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.799 0.201 0.000
E03.8 Other specified hypothyroidism
0.799 0.201 0.000
M86 Osteomyelitis
0.795 0.205 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.794 0.206 0.000
V10-V19 Pedal cyclist injured in transport accident
0.792 0.208 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.787 0.213 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.787 0.213 0.000
W22 Striking against or struck by other objects
0.783 0.217 0.000
M00-M03 Infectious arthropathies
0.782 0.218 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.782 0.218 0.000
H73 Other disorders of tympanic membrane
0.782 0.218 0.000
T92.1 Sequelae of fracture of arm
0.782 0.218 0.000
E07 Other disorders of thyroid
0.780 0.220 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.780 0.220 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.778 0.222 0.000
V20-V29 Motorcycle rider injured in transport accident
0.775 0.225 0.000
E10.5 With peripheral circulatory complications
0.775 0.225 0.000
Y10-Y34 Event of undetermined intent
0.772 0.228 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.771 0.229 0.000
M22.2 Patellofemoral disorders
0.770 0.230 0.000
W50-W64 Exposure to animate mechanical forces
0.767 0.233 0.000
E05.8 Other thyrotoxicosis
0.767 0.233 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.766 0.234 0.000
Q24.5 Malformation of coronary vessels
0.766 0.234 0.000
T92.0 Sequelae of open wound of upper limb
0.766 0.234 0.000
H92.1 Otorrhoea
0.765 0.235 0.000
M34 Systemic sclerosis
0.764 0.236 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.762 0.238 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.760 0.240 0.000
L10-L14 Bullous disorders
0.758 0.242 0.000
E06 Thyroiditis
0.758 0.242 0.000
M89 Other disorders of bone
0.757 0.242 0.000
E14.6 With other specified complications
0.757 0.243 0.000
M22.3 Other derangements of patella
0.756 0.244 0.000
H80-H83 Diseases of inner ear
0.756 0.244 0.000
H72.1 Attic perforation of tympanic membrane
0.754 0.246 0.000
W75-W84 Other accidental threats to breathing
0.754 0.246 0.000
M31.7 Microscopic polyangiitis
0.754 0.246 0.000
L40-L45 Papulosquamous disorders
0.753 0.246 0.000
X10-X19 Contact with heat and hot substances
0.752 0.248 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.751 0.249 0.000
W21 Striking against or struck by sports equipment
0.750 0.250 0.000
X00-X09 Exposure to smoke, fire and flames
0.746 0.254 0.000
H70 Mastoiditis and related conditions
0.743 0.257 0.000
V98-V99 Other and unspecified transport accidents
0.741 0.259 0.000
H72.0 Central perforation of tympanic membrane
0.741 0.259 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.741 0.259 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.738 0.262 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.737 0.263 0.000
W44 Foreign body entering into or through eye or natural orifice
0.737 0.263 0.000
Q24.9 Congenital malformation of the heart, unspecified
0.737 0.263 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.736 0.264 0.000
E11 Non-insulin-dependent diabetes mellitus
0.735 0.265 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.734 0.266 0.000
E03.1 Congenital hypothyroidism without goitre
0.733 0.266 0.000
L60-L75 Disorders of skin appendages
0.733 0.267 0.000
E27.8 Other specified disorders of adrenal gland
0.731 0.269 0.000
E58 Dietary calcium deficiency
0.727 0.273 0.000
X20-X29 Contact with venomous animals and plants
0.727 0.273 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.727 0.273 0.000
E13 Other specified diabetes mellitus
0.724 0.275 0.000
E10.8 With unspecified complications
0.724 0.276 0.000
E20 Hypoparathyroidism
0.724 0.276 0.000
Chapter XXII Codes for special purposes
0.723 0.277 0.000
E21.3 Hyperparathyroidism, unspecified
0.723 0.277 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.721 0.279 0.000
E34 Other endocrine disorders
0.719 0.280 0.000
V90-V94 Water transport accidents
0.718 0.282 0.000
D80-D89 Certain disorders involving the immune mechanism
0.718 0.282 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
Q27 Other congenital malformations of peripheral vascular system
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
W34 Discharge from other and unspecified firearms
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.283 0.000
S20-S29 Injuries to the thorax
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.715 0.285 0.000
E05.4 Thyrotoxicosis factitia
0.715 0.285 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.715 0.285 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.715 0.285 0.000
E10.7 With multiple complications
0.715 0.285 0.000
L40 Psoriasis
0.715 0.285 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.714 0.286 0.000
H68 Eustachian salpingitis and obstruction
0.714 0.286 0.000
H67 Otitis media in diseases classified elsewhere
0.714 0.286 0.000
L03.3 Cellulitis of trunk
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.713 0.287 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.711 0.288 0.000
M65.8 Other synovitis and tenosynovitis
0.711 0.289 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.710 0.290 0.000
Q23.1 Congenital insufficiency of aortic valve
0.710 0.290 0.000
E10.6 With other specified complications
0.710 0.290 0.000
M65.2 Calcific tendinitis
0.709 0.290 0.000
M65.0 Abscess of tendon sheath
0.709 0.290 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.709 0.290 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.709 0.290 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.709 0.290 0.000
M08 Juvenile arthritis
0.709 0.290 0.000
M62 Other disorders of muscle
0.708 0.291 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.708 0.292 0.000
E32 Diseases of thymus
0.708 0.292 0.000
E31 Polyglandular dysfunction
0.708 0.292 0.000
E30 Disorders of puberty, not elsewhere classified
0.708 0.292 0.000
E25 Adrenogenital disorders
0.708 0.292 0.000
Q07 Other congenital malformations of nervous system
0.708 0.292 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.707 0.293 0.000
T00-T07 Injuries involving multiple body regions
0.707 0.293 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.706 0.293 0.000
E63 Other nutritional deficiencies
0.706 0.293 0.000
E56 Other vitamin deficiencies
0.706 0.293 0.000
E50 Vitamin A deficiency
0.706 0.293 0.000
E60 Dietary zinc deficiency
0.706 0.293 0.000
E59 Dietary selenium deficiency
0.706 0.293 0.000
E54 Ascorbic acid deficiency
0.706 0.293 0.000
E52 Niacin deficiency [pellagra]
0.706 0.293 0.000
Q23.0 Congenital stenosis of aortic valve
0.705 0.295 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.705 0.295 0.000
M24.5 Contracture of joint
0.704 0.296 0.000
L01 Impetigo
0.703 0.297 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.702 0.298 0.000
L00 Staphylococcal scalded skin syndrome
0.701 0.299 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.701 0.299 0.000
M43.2 Other fusion of spine
0.699 0.301 0.000
S20 Superficial injury of thorax
0.699 0.301 0.000
M12.3 Palindromic rheumatism
0.698 0.302 0.000
W22.9 Unspecified place
0.698 0.302 0.000
H65 Nonsuppurative otitis media
0.698 0.302 0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.696 0.304 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.695 0.305 0.000
L40.5 Arthropathic psoriasis
0.694 0.306 0.000
M86.6 Other chronic osteomyelitis
0.693 0.307 0.000
E51 Thiamine deficiency
0.693 0.307 0.000
Q35-Q37 Cleft lip and cleft palate
0.693 0.307 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.693 0.307 0.000
M24.28 Disorder of ligament (Other)
0.693 0.307 0.000
M87.9 Osteonecrosis, unspecified
0.691 0.309 0.000
E14.1 With ketoacidosis
0.691 0.309 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.691 0.309 0.000
Q05.9 Spina bifida, unspecified
0.690 0.310 0.000
E10.1 With ketoacidosis
0.688 0.312 0.000
M45-M49 Spondylopathies
0.687 0.313 0.000
M21.7 Unequal limb length (acquired)
0.687 0.313 0.000
Chapter VI Diseases of the nervous system
0.687 0.313 0.000
M06.8 Other specified rheumatoid arthritis
0.686 0.314 0.000
M06.2 Rheumatoid bursitis
0.686 0.314 0.000
M06.1 Adult-onset Still's disease
0.686 0.314 0.000
E53.1 Pyridoxine deficiency
0.685 0.314 0.000
E53.0 Riboflavin deficiency
0.685 0.314 0.000
D86 Sarcoidosis
0.685 0.315 0.000
E27.5 Adrenomedullary hyperfunction
0.684 0.316 0.000
E27.0 Other adrenocortical overactivity
0.684 0.316 0.000
Q25.1 Coarctation of aorta
0.683 0.317 0.000
M14 Arthropathies in other diseases classified elsewhere
0.682 0.318 0.000
W27 Contact with nonpowered hand tool
0.680 0.320 0.000
M07.6 Other enteropathic arthropathies
0.680 0.320 0.000
M07.5 Arthropathy in ulcerative colitis
0.680 0.320 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.680 0.320 0.000
M07.2 Psoriatic spondylitis
0.680 0.320 0.000
M07.1 Arthritis mutilans
0.680 0.320 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.680 0.320 0.000
W45 Foreign body or object entering through skin
0.679 0.321 0.000
M22.0 Recurrent dislocation of patella
0.678 0.322 0.000
M22.8 Other disorders of patella
0.677 0.323 0.000
E04 Other non-toxic goitre
0.677 0.323 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.677 0.323 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.677 0.323 0.000
Q26 Congenital malformations of great veins
0.676 0.324 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.676 0.324 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.676 0.324 0.000
M21.3 Wrist or foot drop (acquired)
0.676 0.324 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.676 0.324 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.675 0.325 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.675 0.325 0.000
M22.1 Recurrent subluxation of patella
0.674 0.326 0.000
M21.9 Acquired deformity of limb, unspecified
0.673 0.326 0.000
L73 Other follicular disorders
0.673 0.327 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.673 0.327 0.000
M02 Reactive arthropathies
0.672 0.328 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.672 0.328 0.000
G30-G32 Other degenerative diseases of the nervous system
0.672 0.328 0.000
M89.8 Other specified disorders of bone
0.671 0.329 0.000
E14.5 With peripheral circulatory complications
0.671 0.329 0.000
H73.8 Other specified disorders of tympanic membrane
0.670 0.330 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.669 0.331 0.000
M31.8 Other specified necrotising vasculopathies
0.669 0.331 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.669 0.331 0.000
M31.2 Lethal midline granuloma
0.669 0.331 0.000
M31.0 Hypersensitivity angiitis
0.669 0.331 0.000
E22.0 Acromegaly and pituitary gigantism
0.668 0.332 0.000
E29.9 Testicular dysfunction, unspecified
0.667 0.333 0.000
E29.8 Other testicular dysfunction
0.667 0.333 0.000
E29.0 Testicular hyperfunction
0.667 0.333 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.667 0.333 0.000
E61.2 Magnesium deficiency
0.667 0.333 0.000
M30.0 Polyarteritis nodosa
0.667 0.333 0.000
Q03 Congenital hydrocephalus
0.667 0.333 0.000
M66 Spontaneous rupture of synovium and tendon
0.667 0.333 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.666 0.334 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.666 0.334 0.000
G30 Alzheimer's disease
0.665 0.335 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.665 0.335 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.665 0.335 0.000
Q05.7 Lumbar spina bifida without hydrocephalus
0.665 0.335 0.000
M22.9 Disorder of patella, unspecified
0.664 0.336 0.000
Q21 Congenital malformations of cardiac septa
0.663 0.337 0.000
M33 Dermatopolymyositis
0.663 0.337 0.000
E14.4 With neurological complications
0.662 0.338 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.662 0.338 0.000
M05.2 Rheumatoid vasculitis
0.661 0.339 0.000
E14.7 With multiple complications
0.659 0.340 0.000
E14.2 Withrenal complications
0.659 0.340 0.000
E14.0 With coma
0.659 0.340 0.000
H92.2 Otorrhagia
0.659 0.341 0.000
M07.38 Other psoriatic arthropathies (Other)
0.659 0.341 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.659 0.341 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.659 0.341 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.659 0.341 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.659 0.341 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.659 0.341 0.000
E61.9 Deficiency of nutrient element, unspecified
0.657 0.343 0.000
E61.8 Deficiency of other specified nutrient elements
0.657 0.343 0.000
E61.7 Deficiency of multiple nutrient elements
0.657 0.343 0.000
E61.6 Vanadium deficiency
0.657 0.343 0.000
E61.5 Molybdenum deficiency
0.657 0.343 0.000
E61.4 Chromium deficiency
0.657 0.343 0.000
E61.3 Manganese deficiency
0.657 0.343 0.000
E61.0 Copper deficiency
0.657 0.343 0.000
M24.7 Protrusio acetabuli
0.657 0.343 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.656 0.343 0.000
Y04 Assault by bodily force
0.656 0.344 0.000
Q25.4 Other congenital malformations of aorta
0.656 0.344 0.000
G30.9 Alzheimer's disease, unspecified
0.656 0.344 0.000
E21.4 Other specified disorders of parathyroid gland
0.655 0.344 0.000
M31.9 Necrotising vasculopathy, unspecified
0.655 0.345 0.000
E14.8 With unspecified complications
0.655 0.345 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.653 0.346 0.000
X50-X57 Overexertion, travel and privation
0.653 0.347 0.000
V01-V09 Pedestrian injured in transport accident
0.652 0.348 0.000
W46 Contact with hypodermic needle
0.651 0.348 0.000
W43 Exposure to vibration
0.651 0.348 0.000
W42 Exposure to noise
0.651 0.348 0.000
W41 Exposure to high-pressure jet
0.651 0.348 0.000
W40 Explosion of other materials
0.651 0.348 0.000
W39 Discharge of firework
0.651 0.348 0.000
W38 Explosion and rupture of other specified pressurised devices
0.651 0.348 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.651 0.348 0.000
W36 Explosion and rupture of gas cylinder
0.651 0.348 0.000
W35 Explosion and rupture of boiler
0.651 0.348 0.000
W33 Rifle, shotgun and larger firearm discharge
0.651 0.348 0.000
W32 Handgun discharge
0.651 0.348 0.000
W31 Contact with other and unspecified machinery
0.651 0.348 0.000
W30 Contact with agricultural machinery
0.651 0.348 0.000
W28 Contact with powered lawn mower
0.651 0.348 0.000
W26 Contact with knife, sword or dagger
0.651 0.348 0.000
E11.1 With ketoacidosis
0.652 0.348 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.651 0.349 0.000
M43.0 Spondylolysis
0.651 0.349 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.651 0.349 0.000
M48 Other spondylopathies
0.651 0.349 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.650 0.350 0.000
D50-D53 Nutritional anaemias
0.650 0.350 0.000
M42 Spinal osteochondrosis
0.649 0.351 0.000
M87.2 Osteonecrosis due to previous trauma
0.648 0.352 0.000
M24.6 Ankylosis of joint
0.647 0.353 0.000
Y09 Assault by unspecified means
0.647 0.353 0.000
V48 Car occupant injured in noncollision transport accident
0.645 0.354 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.644 0.356 0.000
E28 Ovarian dysfunction
0.643 0.357 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.643 0.357 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.642 0.358 0.000
T00 Superficial injuries involving multiple body regions
0.642 0.358 0.000
Y89 Sequelae of other external causes
0.641 0.358 0.000
M24.24 Disorder of ligament (Hand)
0.642 0.358 0.000
M06.3 Rheumatoid nodule
0.641 0.359 0.000
D51 Vitamin B12 deficiency anaemia
0.640 0.360 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.638 0.362 0.000
E22.8 Other hyperfunction of pituitary gland
0.638 0.362 0.000
M88 Paget's disease of bone [osteitis deformans]
0.638 0.362 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.638 0.362 0.000
Q06 Other congenital malformations of spinal cord
0.637 0.362 0.000
Q01 Encephalocele
0.637 0.362 0.000
Q00 Anencephaly and similar malformations
0.637 0.362 0.000
Q02 Microcephaly
0.637 0.362 0.000
W25 Contact with sharp glass
0.636 0.364 0.000
M87.8 Other osteonecrosis
0.636 0.364 0.000
M21.8 Other specified acquired deformities of limbs
0.636 0.364 0.000
W21.9 Unspecified place
0.636 0.364 0.000
Q04 Other congenital malformations of brain
0.636 0.364 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.636 0.364 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.636 0.364 0.000
W55 Bitten or struck by other mammals
0.635 0.364 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.635 0.365 0.000
E34.9 Endocrine disorder, unspecified
0.635 0.365 0.000
E27.2 Addisonian crisis
0.635 0.365 0.000
M24.9 Joint derangement, unspecified
0.635 0.365 0.000
M24.23 Disorder of ligament (Forearm)
0.635 0.365 0.000
S40-S49 Injuries to the shoulder and upper arm
0.635 0.365 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.635 0.365 0.000
E06.9 Thyroiditis, unspecified
0.634 0.366 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.634 0.366 0.000
M65.1 Other infective (teno)synovitis
0.634 0.366 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.633 0.367 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.632 0.368 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.632 0.368 0.000
E26 Hyperaldosteronism
0.632 0.368 0.000
Q25.0 Patent ductus arteriosus
0.631 0.368 0.000
E53.9 Vitamin B deficiency, unspecified
0.630 0.370 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.630 0.370 0.000
H66 Suppurative and unspecified otitis media
0.629 0.371 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.629 0.371 0.000
L03.2 Cellulitis of face
0.627 0.373 0.000
L73.8 Other specified follicular disorders
0.627 0.373 0.000
M90 Osteopathies in diseases classified elsewhere
0.626 0.374 0.000
H69 Other disorders of Eustachian tube
0.625 0.375 0.000
Y82 Other and unspecified medical devices associated with adverse incidents
0.625 0.375 0.000
G70-G73 Diseases of myoneural junction and muscle
0.625 0.375 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.624 0.375 0.000
E07.9 Disorder of thyroid, unspecified
0.624 0.376 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.623 0.377 0.000
E04.9 Non-toxic goitre, unspecified
0.623 0.377 0.000
V80-V89 Other land transport accidents
0.622 0.378 0.000
H72.2 Other marginal perforations of tympanic membrane
0.622 0.378 0.000
M34.1 CR(E)ST syndrome
0.622 0.378 0.000
M43.9 Deforming dorsopathy, unspecified
0.621 0.378 0.000
M43.8 Other specified deforming dorsopathies
0.621 0.378 0.000
M43.5 Other recurrent vertebral subluxation
0.621 0.378 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.621 0.378 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.621 0.378 0.000
M80-M85 Disorders of bone density and structure
0.621 0.379 0.000
E11.9 Without complications
0.621 0.379 0.000
Q60-Q64 Congenital malformations of the urinary system
0.621 0.379 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.620 0.380 0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents
0.618 0.382 0.000
S10-S19 Injuries to the neck
0.618 0.382 0.000
M43.6 Torticollis
0.618 0.382 0.000
M21.6 Other acquired deformities of ankle and foot
0.618 0.382 0.000
M40 Kyphosis and lordosis
0.618 0.382 0.000
Q24.6 Congenital heart block
0.618 0.382 0.000
Q24.4 Congenital subaortic stenosis
0.618 0.382 0.000
Q24.3 Pulmonary infundibular stenosis
0.618 0.382 0.000
Q24.2 Cor triatriatum
0.618 0.382 0.000
Q24.1 Levocardia
0.618 0.382 0.000
Q24.0 Dextrocardia
0.618 0.382 0.000
Y71 Cardiovascular devices associated with adverse incidents
0.617 0.383 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.617 0.383 0.000
S90-S99 Injuries to the ankle and foot
0.616 0.384 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.615 0.385 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.615 0.385 0.000
W44.0 Home
0.614 0.386 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.614 0.386 0.000
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures
0.614 0.386 0.000
Y28 Contact with sharp object, undetermined intent
0.612 0.388 0.000
H65.2 Chronic serous otitis media
0.611 0.389 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.611 0.389 0.000
V10 Pedal cyclist injured in collision with pedestrian or animal
0.611 0.389 0.000
M21.2 Flexion deformity
0.610 0.390 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.610 0.390 0.000
L04 Acute lymphadenitis
0.610 0.390 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.609 0.391 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.609 0.391 0.000
M60 Myositis
0.608 0.392 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.608 0.392 0.000
E10.2 With renal complications
0.607 0.393 0.000
D86.1 Sarcoidosis of lymph nodes
0.607 0.393 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.607 0.393 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.606 0.394 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.606 0.394 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.606 0.394 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.606 0.394 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.606 0.394 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.606 0.394 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.606 0.394 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.606 0.394 0.000
M24.26 Disorder of ligament (Lower leg)
0.606 0.394 0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.605 0.395 0.000
M11 Other crystal arthropathies
0.604 0.395 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.604 0.396 0.000
M05.8 Other seropositive rheumatoid arthritis
0.603 0.397 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.603 0.397 0.000
M05.1 Rheumatoid lung disease
0.603 0.397 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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