TreeWAS – Variant ID: rs16982520

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	1.000	0.000	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.760	0.240	0.000
I25 Chronic ischaemic heart disease	0.758	0.242	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.740	0.260	0.000
I10-I15 Hypertensive diseases	0.725	0.275	0.000
I25.2 Old myocardial infarction	0.704	0.296	0.000
I11 Hypertensive heart disease	0.626	0.374	0.000
I20-I25 Ischaemic heart diseases	0.587	0.413	0.000
I25.4 Coronary artery aneurysm	0.579	0.421	0.000
I25.1 Atherosclerotic heart disease	0.578	0.422	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.553	0.447	0.000
Chapter IX Diseases of the circulatory system	0.553	0.447	0.000
I25.6 Silent myocardial ischaemia	0.543	0.457	0.000
I15 Secondary hypertension	0.540	0.460	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.527	0.473	0.000
I13 Hypertensive heart and renal disease	0.519	0.480	0.000
I25.3 Aneurysm of heart	0.508	0.492	0.000
I25.5 Ischaemic cardiomyopathy	0.500	0.500	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.499	0.500	0.000
I21 Acute myocardial infarction	0.489	0.511	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.486	0.514	0.000
I05-I09 Chronic rheumatic heart diseases	0.437	0.563	0.000
I24 Other acute ischaemic heart diseases	0.434	0.566	0.000
I15.1 Hypertension secondary to other renal disorders	0.408	0.592	0.000
I00-I02 Acute rheumatic fever	0.396	0.604	0.000
I60-I69 Cerebrovascular diseases	0.391	0.609	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.389	0.611	0.000
I15.9 Seconday hypertension, unspecified	0.387	0.613	0.000
I15.8 Other secondary hypertension	0.387	0.613	0.000
I15.2 Hypertension secondary to endocrine disorders	0.387	0.613	0.000
I15.0 Renovascular hypertension	0.387	0.613	0.000
I23 Certain current complications following acute myocardial infarction	0.378	0.622	0.000
I07 Rheumatic tricuspid valve diseases	0.376	0.624	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.372	0.627	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.372	0.627	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.372	0.627	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.372	0.627	0.000
I63 Cerebral infarction	0.368	0.632	0.000
I05 Rheumatic mitral valve diseases	0.364	0.636	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.359	0.641	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.350	0.649	0.000
I63.9 Cerebral infarction, unspecified	0.345	0.655	0.000
I69 Sequelae of cerebrovascular disease	0.341	0.659	0.000
I09 Other rheumatic heart diseases	0.335	0.665	0.000
I07.1 Tricuspid insufficiency	0.332	0.668	0.000
I21.4 Acute subendocardial myocardial infarction	0.327	0.673	0.000
I06 Rheumatic aortic valve diseases	0.320	0.680	0.000
I24.1 Dressler's syndrome	0.311	0.689	0.000
I05.1 Rheumatic mitral insufficiency	0.309	0.691	0.000
I63.8 Other cerebral infarction	0.307	0.693	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.305	0.695	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.302	0.698	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.301	0.699	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.299	0.701	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.296	0.704	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.293	0.707	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.289	0.711	0.000
I02 Rheumatic chorea	0.284	0.716	0.000
I01 Rheumatic fever with heart involvement	0.284	0.716	0.000
I00 Rheumatic fever without mention of heart involvement	0.284	0.716	0.000
I62 Other nontraumatic intracranial haemorrhage	0.284	0.716	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.283	0.717	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.282	0.718	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.280	0.719	0.000
I22 Subsequent myocardial infarction	0.280	0.720	0.000
I05.9 Mitral valve disease, unspecified	0.279	0.721	0.000
I60 Subarachnoid haemorrhage	0.273	0.727	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.272	0.728	0.000
I05.0 Mitral stenosis	0.271	0.729	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.271	0.729	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.271	0.729	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.271	0.729	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.271	0.729	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.271	0.729	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.271	0.729	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.271	0.729	0.000
I07.9 Tricuspid valve disease, unspecified	0.269	0.730	0.000
I07.8 Other tricuspid valve diseases	0.269	0.730	0.000
I07.2 Tricuspid stenosis with insufficiency	0.269	0.730	0.000
I07.0 Tricuspid stenosis	0.269	0.730	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.264	0.736	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.264	0.736	0.000
I09.9 Rheumatic heart disease, unspecified	0.262	0.738	0.000
I05.8 Other mitral valve diseases	0.261	0.739	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.260	0.740	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.251	0.749	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.246	0.754	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.244	0.755	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.243	0.757	0.000
I69.3 Sequelae of cerebral infarction	0.242	0.758	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.240	0.760	0.000
I09.8 Other specified rheumatic heart diseases	0.240	0.760	0.000
I09.2 Chronic rheumatic pericarditis	0.240	0.760	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.240	0.760	0.000
I09.0 Rheumatic myocarditis	0.240	0.760	0.000
I06.0 Rheumatic aortic stenosis	0.236	0.764	0.000
I05.2 Mitral stenosis with insufficiency	0.232	0.768	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.231	0.768	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.231	0.769	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.229	0.770	0.000
I06.8 Other rheumatic aortic valve diseases	0.229	0.770	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.229	0.770	0.000
I06.1 Rheumatic aortic insufficiency	0.229	0.770	0.000
I23.8 Other current complications following acute myocardial infarction	0.227	0.772	0.000
I22.8 Subsequent myocardial infarction of other sites	0.227	0.773	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.220	0.780	0.000
I97.1 Other functional disturbances following cardiac surgery	0.220	0.780	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.219	0.781	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.219	0.781	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.219	0.781	0.000
I65.1 Occlusion and stenosis of basilar artery	0.219	0.781	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.216	0.784	0.000
I65.2 Occlusion and stenosis of carotid artery	0.215	0.785	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.214	0.785	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.214	0.785	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.214	0.785	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.214	0.785	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.214	0.785	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.208	0.792	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.206	0.794	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.205	0.795	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.204	0.796	0.000
I01.8 Other acute rheumatic heart disease	0.204	0.796	0.000
I01.2 Acute rheumatic myocarditis	0.204	0.796	0.000
I01.1 Acute rheumatic endocarditis	0.204	0.796	0.000
I01.0 Acute rheumatic pericarditis	0.204	0.796	0.000
I02.9 Rheumatic chorea without heart involvement	0.204	0.796	0.000
I02.0 Rheumatic chorea with heart involvement	0.204	0.796	0.000
I62.1 Nontraumatic extradural haemorrhage	0.203	0.796	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.203	0.797	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.201	0.799	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.201	0.799	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.201	0.799	0.000
I68.0 Cerebral amyloid angiopathy	0.201	0.799	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.195	0.804	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.195	0.804	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.195	0.804	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.191	0.809	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.186	0.814	0.000
I12 Hypertensive renal disease	0.181	0.818	0.001
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.181	0.819	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.177	0.823	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.175	0.825	0.000
I97.0 Postcardiotomy syndrome	0.175	0.825	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.174	0.825	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.172	0.827	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.172	0.827	0.000
I98.0 Cardiovascular syphilis	0.172	0.827	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.171	0.829	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.170	0.830	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.166	0.833	0.000
I99 Other and unspecified disorders of circulatory system	0.164	0.836	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.163	0.837	0.000
I72 Other aneurysm	0.158	0.842	0.000
I72.8 Aneurysm of other specified arteries	0.154	0.846	0.000
I24.8 Other forms of acute ischaemic heart disease	0.152	0.848	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.150	0.849	0.000
I60.8 Other subarachnoid haemorrhage	0.149	0.851	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.148	0.851	0.000
I20 Angina pectoris	0.134	0.866	0.000
I67 Other cerebrovascular diseases	0.132	0.868	0.000
I61 Intracerebral haemorrhage	0.128	0.871	0.000
I28 Other diseases of pulmonary vessels	0.127	0.873	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.125	0.874	0.000
I72.1 Aneurysm of artery of upper extremity	0.126	0.874	0.000
I78 Diseases of capillaries	0.125	0.875	0.000
I72.2 Aneurysm of renal artery	0.120	0.880	0.000
I74 Arterial embolism and thrombosis	0.120	0.880	0.000
I72.3 Aneurysm of iliac artery	0.117	0.883	0.000
I72.9 Aneurysm of unspecified site	0.117	0.883	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.114	0.886	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.113	0.887	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.113	0.887	0.000
I61.8 Other intracerebral haemorrhage	0.107	0.893	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.105	0.895	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.104	0.896	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.103	0.897	0.000
I67.8 Other specified cerebrovascular diseases	0.102	0.898	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.098	0.901	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.095	0.905	0.000
I67.5 Moyamoya disease	0.095	0.905	0.000
I67.4 Hypertensive encephalopathy	0.095	0.905	0.000
I67.3 Progressive vascular leukoencephalopathy	0.095	0.905	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.095	0.905	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.093	0.906	0.000
I73 Other peripheral vascular diseases	0.093	0.906	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.093	0.907	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.092	0.907	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.092	0.907	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.091	0.909	0.000
I28.8 Other specified diseases of pulmonary vessels	0.091	0.909	0.000
I28.1 Aneurysm of pulmonary artery	0.091	0.909	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.091	0.909	0.000
I78.9 Disease of capillaries, unspecified	0.090	0.910	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.089	0.911	0.000
I67.2 Cerebral atherosclerosis	0.088	0.912	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.086	0.913	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.086	0.914	0.000
I78.8 Other diseases of capillaries	0.085	0.915	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.082	0.918	0.000
I79.1 Aortitis in diseases classified elsewhere	0.082	0.918	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.082	0.918	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.082	0.918	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.081	0.919	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.080	0.920	0.000
I20.1 Angina pectoris with documented spasm	0.080	0.920	0.000
I70 Atherosclerosis	0.078	0.922	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.077	0.923	0.000
I20.0 Unstable angina	0.077	0.923	0.000
I72.0 Aneurysm of carotid artery	0.075	0.925	0.000
I78.1 Naevus, nonneoplastic	0.075	0.925	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.074	0.925	0.000
I74.5 Embolism and thrombosis of iliac artery	0.074	0.926	0.000
I26 Pulmonary embolism	0.074	0.926	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.074	0.926	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.073	0.927	0.000
I74.8 Embolism and thrombosis of other arteries	0.073	0.927	0.000
I08 Multiple valve diseases	0.073	0.927	0.000
I72.4 Aneurysm of artery of lower extremity	0.072	0.928	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.069	0.930	0.000
I73.8 Other specified peripheral vascular diseases	0.068	0.932	0.000
I73.0 Raynaud's syndrome	0.067	0.933	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.067	0.933	0.000
I95 Hypotension	0.066	0.934	0.000
I77 Other disorders of arteries and arterioles	0.065	0.935	0.000
I20.9 Angina pectoris, unspecified	0.064	0.936	0.000
I12.9 Hypertensive renal disease without renal failure	0.058	0.941	0.001
I08.9 Multiple valve disease, unspecified	0.058	0.941	0.000
I70.9 Generalised and unspecified atherosclerosis	0.056	0.943	0.000
I70.8 Atherosclerosis of other arteries	0.056	0.943	0.000
I21.9 Acute myocardial infarction, unspecified	0.053	0.947	0.000
I70.1 Atherosclerosis of renal artery	0.052	0.947	0.001
I20.8 Other forms of angina pectoris	0.052	0.948	0.000
I95.0 Idiopathic hypotension	0.051	0.949	0.000
I77.8 Other specified disorders of arteries and arterioles	0.051	0.949	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.050	0.950	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.048	0.952	0.000
I77.2 Rupture of artery	0.048	0.952	0.000
I08.8 Other multiple valve diseases	0.047	0.953	0.000
I77.5 Necrosis of artery	0.046	0.953	0.000
I77.4 Coeliac artery compression syndrome	0.046	0.953	0.000
I77.3 Arterial fibromuscular dysplasia	0.046	0.953	0.000
I70.0 Atherosclerosis of aorta	0.046	0.954	0.001
I27 Other pulmonary heart diseases	0.045	0.955	0.000
I08.0 Disorders of both mitral and aortic valves	0.045	0.955	0.000
I67.1 Cerebral aneurysm, nonruptured	0.045	0.955	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.043	0.957	0.000
I95.1 Orthostatic hypotension	0.042	0.958	0.000
J98.4 Other disorders of lung	0.041	0.959	0.000
I77.0 Arteriovenous fistula, acquired	0.041	0.959	0.000
I71 Aortic aneurysm and dissection	0.041	0.959	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.040	0.959	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.040	0.959	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.040	0.959	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.040	0.959	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.039	0.960	0.001
I70.11 Atherosclerosis of renal artery (with gangrene)	0.038	0.962	0.001
I95.8 Other hypotension	0.036	0.964	0.000
I73.9 Peripheral vascular disease, unspecified	0.035	0.965	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.035	0.965	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.035	0.965	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.034	0.965	0.001
I95.2 Hypotension due to drugs	0.034	0.966	0.000
I77.1 Stricture of artery	0.034	0.966	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.033	0.966	0.001
H21 Other disorders of iris and ciliary body	0.033	0.967	0.000
I27.1 Kyphoscoliotic heart disease	0.033	0.967	0.000
H18 Other disorders of cornea	0.032	0.968	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.032	0.968	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.031	0.969	0.000
H17 Corneal scars and opacities	0.031	0.969	0.000
H20 Iridocyclitis	0.031	0.969	0.000
I27.8 Other specified pulmonary heart diseases	0.030	0.970	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.030	0.970	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.029	0.970	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.029	0.970	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.029	0.970	0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.029	0.971	0.000
H18.5 Hereditary corneal dystrophies	0.029	0.971	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.028	0.971	0.001
I08.2 Disorders of both aortic and tricuspid valves	0.028	0.971	0.001
I71.3 Abdominal aortic aneurysm, ruptured	0.028	0.971	0.000
H15 Disorders of sclera	0.028	0.971	0.000
H17.9 Corneal scar and opacity, unspecified	0.028	0.972	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.028	0.972	0.000
H21.0 Hyphaema	0.028	0.972	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.028	0.972	0.000
H16 Keratitis	0.027	0.973	0.000
H20.0 Acute and subacute iridocyclitis	0.027	0.973	0.000
H18.4 Corneal degeneration	0.026	0.974	0.000
H21.8 Other specified disorders of iris and ciliary body	0.026	0.974	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.025	0.974	0.000
I27.9 Pulmonary heart disease, unspecified	0.025	0.975	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.025	0.975	0.000
H18.2 Other corneal oedema	0.025	0.975	0.000
H20.1 Chronic iridocyclitis	0.025	0.975	0.000
H18.8 Other specified disorders of cornea	0.024	0.976	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.024	0.976	0.000
H21.4 Pupillary membranes	0.024	0.976	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.024	0.976	0.000
H21.2 Degeneration of iris and ciliary body	0.024	0.976	0.000
I67.9 Cerebrovascular disease, unspecified	0.024	0.976	0.000
H15.1 Episcleritis	0.024	0.976	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.024	0.976	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.023	0.977	0.001
H20.9 Iridocyclitis, unspecified	0.023	0.977	0.000
H18.7 Other corneal deformities	0.023	0.977	0.000
H18.3 Changes in corneal membranes	0.023	0.977	0.000
H18.1 Bullous keratopathy	0.023	0.977	0.000
H18.0 Corneal pigmentations and deposits	0.023	0.977	0.000
H17.8 Other corneal scars and opacities	0.023	0.977	0.000
I77.6 Arteritis, unspecified	0.023	0.977	0.000
I27.2 Other secondary pulmonary hypertension	0.023	0.977	0.000
H17.1 Other central corneal opacity	0.022	0.977	0.000
H17.0 Adherent leukoma	0.022	0.977	0.000
H20.2 Lens-induced iridocyclitis	0.022	0.978	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.022	0.978	0.000
H18.9 Disorder of cornea, unspecified	0.022	0.978	0.000
H18.6 Keratoconus	0.022	0.978	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.022	0.978	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.022	0.978	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.022	0.978	0.000
H16.0 Corneal ulcer	0.022	0.978	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.021	0.979	0.000
H15.9 Disorder of sclera, unspecified	0.021	0.979	0.000
H15.8 Other disorders of sclera	0.021	0.979	0.000
H15.0 Scleritis	0.021	0.979	0.000
H16.8 Other keratitis	0.020	0.980	0.000
H16.4 Corneal neovascularisation	0.020	0.980	0.000
H16.3 Interstitial and deep keratitis	0.020	0.980	0.000
H16.2 Keratoconjunctivitis	0.020	0.980	0.000
I12.0 Hypertensive renal disease with renal failure	0.018	0.981	0.001
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.018	0.982	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.018	0.982	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.018	0.982	0.000
H20.8 Other iridocyclitis	0.018	0.982	0.000
I27.0 Primary pulmonary hypertension	0.017	0.982	0.000
H16.9 Keratitis, unspecified	0.017	0.983	0.000
I71.0 Dissection of aorta [any part]	0.017	0.983	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.014	0.985	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.014	0.986	0.000
H61.2 Impacted cerumen	0.000	0.986	0.014
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.013	0.987	0.000
Z03.4 Observation for suspected myocardial infarction	0.013	0.987	0.000
H61 Other disorders of external ear	0.000	0.988	0.012
H92.1 Otorrhoea	0.000	0.988	0.012
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.011	0.988	0.001
H61.1 Non-infective disorders of pinna	0.000	0.989	0.011
H92 Otalgia and effusion of ear	0.000	0.989	0.011
H61.3 Acquired stenosis of external ear canal	0.000	0.990	0.010
H92.0 Otalgia	0.000	0.990	0.010
H90 Conductive and sensorineural hearing loss	0.000	0.990	0.010
I44.0 Atrioventricular block, first degree	0.009	0.991	0.000
H90-H95 Other disorders of ear	0.000	0.991	0.009
I44 Atrioventricular and left bundle-branch block	0.009	0.991	0.000
I44.2 Atrioventricular block, complete	0.009	0.991	0.000
H60-H62 Diseases of external ear	0.000	0.991	0.009
H61.8 Other specified disorders of external ear	0.000	0.991	0.009
H61.9 Disorder of external ear, unspecified	0.000	0.991	0.009
H61.0 Perichondritis of external ear	0.000	0.991	0.008
H90.3 Sensorineural hearing loss, bilateral	0.000	0.992	0.008
I44.3 Other and unspecified atrioventricular block	0.008	0.992	0.000
H92.2 Otorrhagia	0.000	0.992	0.008
I30-I52 Other forms of heart disease	0.008	0.992	0.000
H90.5 Sensorineural hearing loss, unspecified	0.000	0.992	0.008
H90.0 Conductive hearing loss, bilateral	0.000	0.992	0.008
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.992	0.008
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.992	0.008
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.992	0.007
I49.3 Ventricular premature depolarisation	0.007	0.993	0.000
I30 Acute pericarditis	0.007	0.993	0.000
I49 Other cardiac arrhythmias	0.007	0.993	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.993	0.007
H44.2 Degenerative myopia	0.007	0.993	0.000
I49.4 Other and unspecified premature depolarisation	0.007	0.993	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.993	0.007
H44.0 Purulent endophthalmitis	0.007	0.993	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.993	0.007
I44.5 Left posterior fascicular block	0.007	0.993	0.000
I44.4 Left anterior fascicular block	0.007	0.993	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.993	0.007
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.993	0.007
H44 Disorders of globe	0.007	0.993	0.000
H60 Otitis externa	0.000	0.993	0.007
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.993	0.006
I33 Acute and subacute endocarditis	0.006	0.993	0.000
I30.1 Infective pericarditis	0.006	0.994	0.000
K76.8 Other specified diseases of liver	0.006	0.994	0.000
Chapter VIII Diseases of the ear and mastoid process	0.000	0.994	0.006
I49.9 Cardiac arrhythmia, unspecified	0.006	0.994	0.000
I44.1 Atrioventricular block, second degree	0.006	0.994	0.000
I52 Other heart disorders in diseases classified elsewhere	0.006	0.994	0.000
I48 Atrial fibrillation and flutter	0.006	0.994	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.006	0.994	0.000
I41 Myocarditis in diseases classified elsewhere	0.006	0.994	0.000
I40 Acute myocarditis	0.006	0.994	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I32 Pericarditis in diseases classified elsewhere	0.006	0.994	0.000
I30.9 Acute pericarditis, unspecified	0.006	0.994	0.000
H95.1 Other disorders following mastoidectomy	0.000	0.994	0.006
H44.4 Hypotony of eye	0.006	0.994	0.000
H93 Other disorders of ear, not elsewhere classified	0.000	0.994	0.006
I30.8 Other forms of acute pericarditis	0.005	0.995	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.005	0.995	0.000
I36 Nonrheumatic tricuspid valve disorders	0.005	0.995	0.000
J98 Other respiratory disorders	0.005	0.995	0.000
I49.2 Junctional premature depolarisation	0.005	0.995	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.005	0.995	0.000
H60.1 Cellulitis of external ear	0.000	0.995	0.005
I33.0 Acute and subacute infective endocarditis	0.005	0.995	0.000
I44.6 Other and unspecified fascicular block	0.005	0.995	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.995	0.005
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.995	0.005
H60.3 Other infective otitis externa	0.000	0.995	0.005
I37 Pulmonary valve disorders	0.005	0.995	0.000
I42 Cardiomyopathy	0.005	0.995	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.000	0.995	0.005
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.995	0.005
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.995	0.005
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
H62.2 Otitis externa in mycoses	0.000	0.995	0.005
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.995	0.005
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.995	0.005
H60.8 Other otitis externa	0.000	0.995	0.005
H44.9 Disorder of globe, unspecified	0.005	0.995	0.000
H44.8 Other disorders of globe	0.005	0.995	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.005	0.995	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.005	0.995	0.000
H44.5 Degenerated conditions of globe	0.005	0.995	0.000
H44.3 Other degenerative disorders of globe	0.005	0.995	0.000
H44.1 Other endophthalmitis	0.005	0.995	0.000
H60.2 Malignant otitis externa	0.000	0.995	0.005
H60.0 Abscess of external ear	0.000	0.995	0.005
I95.9 Hypotension, unspecified	0.005	0.995	0.000
I33.9 Acute endocarditis, unspecified	0.005	0.995	0.000
H60.5 Acute otitis externa, non-infective	0.000	0.995	0.005
C15.4 Middle third of oesophagus	0.005	0.995	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.000	0.995	0.005
I42.2 Other hypertrophic cardiomyopathy	0.005	0.995	0.000
I49.1 Atrial premature depolarisation	0.005	0.995	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.005	0.995	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.004	0.995	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.004	0.995	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.004	0.995	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.004	0.995	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.004	0.995	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.004	0.995	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.004	0.995	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.004	0.995	0.000
I40.9 Acute myocarditis, unspecified	0.004	0.995	0.000
I40.8 Other acute myocarditis	0.004	0.995	0.000
I40.1 Isolated myocarditis	0.004	0.995	0.000
I40.0 Infective myocarditis	0.004	0.995	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.004	0.995	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.004	0.995	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.004	0.995	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.004	0.995	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.004	0.995	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.004	0.995	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.004	0.995	0.000
I48.4 Atypical atrial flutter	0.004	0.995	0.000
I48.3 Typical atrial flutter	0.004	0.995	0.000
I48.2 Chronic atrial fibrillation	0.004	0.995	0.000
I48.1 Persistent atrial fibrillation	0.004	0.995	0.000
I48.0 Paroxysmal atrial fibrillation	0.004	0.995	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.004	0.995	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.004	0.995	0.000
H60.4 Cholesteatoma of external ear	0.000	0.995	0.004
Z11 Special screening examination for infectious and parasitic diseases	0.005	0.995	0.000
H93.8 Other specified disorders of ear	0.000	0.995	0.005
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.005	0.995	0.000
Z11.2 Special screening examination for other bacterial diseases	0.004	0.996	0.000
I34 Nonrheumatic mitral valve disorders	0.004	0.996	0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.004	0.996	0.000
C15 Malignant neoplasm of oesophagus	0.004	0.996	0.000
H60.9 Otitis externa, unspecified	0.000	0.996	0.004
H93.3 Disorders of acoustic nerve	0.000	0.996	0.004
H93.2 Other abnormal auditory perceptions	0.000	0.996	0.004
H93.0 Degenerative and vascular disorders of ear	0.000	0.996	0.004
J98.9 Respiratory disorder, unspecified	0.004	0.996	0.000
J98.2 Interstitial emphysema	0.004	0.996	0.000
Z11.5 Special screening examination for other viral diseases	0.004	0.996	0.000
H93.9 Disorder of ear, unspecified	0.000	0.996	0.004
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.004	0.996	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.004	0.996	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.004	0.996	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.004	0.996	0.000
C15.3 Upper third of oesophagus	0.004	0.996	0.000
J98.3 Compensatory emphysema	0.004	0.996	0.000
C15.5 Lower third of oesophagus	0.004	0.996	0.000
S22.30 Fracture of rib (closed)	0.004	0.996	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.004	0.996	0.000
C15.9 Oesophagus, unspecified	0.004	0.996	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.004	0.996	0.000
I42.9 Cardiomyopathy, unspecified	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations