TreeWAS – Variant ID: rs16984239

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.020	0.980	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.018	0.982	0.000
Z43.3 Attention to colostomy	0.000	0.985	0.015
M47.9 Spondylosis, unspecified	0.014	0.986	0.000
Z43.2 Attention to ileostomy	0.000	0.987	0.013
Z43 Attention to artificial openings	0.000	0.987	0.013
N28.9 Disorder of kidney and ureter, unspecified	0.012	0.988	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.011	0.989	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.000	0.989	0.011
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.010	0.989	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.010	0.990	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.010	0.990	0.000
Z43.5 Attention to cyctostomy	0.000	0.990	0.010
Z43.9 Attention to unspecified artificial opening	0.000	0.991	0.009
Z43.7 Attention to artificial vagina	0.000	0.991	0.009
M47.94 Spondylosis, unspecified (Thoracic region)	0.009	0.991	0.000
Z43.0 Attention to tracheostomy	0.000	0.991	0.009
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.009	0.991	0.000
Z47.8 Other specified orthopaedic follow-up care	0.000	0.991	0.009
Z43.1 Attention to gastrostomy	0.000	0.991	0.008
Z43.6 Attention to other artificial openings of urinary tract	0.000	0.992	0.008
Z43.8 Attention to other artificial openings	0.000	0.992	0.007
M47.99 Spondylosis, unspecified (Site unspecified)	0.006	0.994	0.000
Z37.2 Twins, both liveborn	0.006	0.994	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.994	0.006
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.994	0.006
R07.2 Precordial pain	0.005	0.995	0.000
Q43.0 Meckel's diverticulum	0.004	0.996	0.000
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
T42.4 Benzodiazepines	0.004	0.996	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.004	0.996	0.000
Q43.8 Other specified congenital malformations of intestine	0.004	0.996	0.000
M54.16 Radiculopathy (Lumbar region)	0.004	0.996	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.004	0.996	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.000	0.996	0.004
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
Q43.3 Congenital malformations of intestinal fixation	0.004	0.996	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
S82.60 Fracture of lateral malleolus (closed)	0.004	0.996	0.000
C01 Malignant neoplasm of base of tongue	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
R60.0 Localised oedema	0.004	0.996	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
M54.1 Radiculopathy	0.004	0.996	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.004	0.996	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.996	0.000
Q43.7 Persistent cloaca	0.003	0.997	0.000
Q43.6 Congenital fistula of rectum and anus	0.003	0.997	0.000
Q43.5 Ectopic anus	0.003	0.997	0.000
Q43.4 Duplication of intestine	0.003	0.997	0.000
Q43.2 Other congenital functional disorders of colon	0.003	0.997	0.000
Q43.1 Hirschsprung's disease	0.003	0.997	0.000
Q38.7 Pharyngeal pouch	0.003	0.997	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
N48.6 Balanitis xerotica obliterans	0.000	0.997	0.003
L57.0 Actinic keratosis	0.003	0.997	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.003	0.997	0.000
Q25.0 Patent ductus arteriosus	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
S52.6 Fracture of lower end of both ulna and radius	0.000	0.997	0.003
Q25 Congenital malformations of great arteries	0.003	0.997	0.000
Q87.4 Marfan's syndrome	0.003	0.997	0.000
J18.0 Bronchopneumonia, unspecified	0.003	0.997	0.000
M54.14 Radiculopathy (Thoracic region)	0.003	0.997	0.000
J14 Pneumonia due to Haemophilus influenzae	0.003	0.997	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.997	0.003
Q20-Q28 Congenital malformations of the circulatory system	0.003	0.997	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.003	0.997	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.003	0.997	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Q40.2 Other specified congenital malformations of stomach	0.003	0.997	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.003	0.997	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.003	0.997	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.003	0.997	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.003	0.997	0.000
Q38.8 Other congenital malformations of pharynx	0.003	0.997	0.000
Q38.6 Other congenital malformations of mouth	0.003	0.997	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.003	0.997	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.003	0.997	0.000
Q38.3 Other congenital malformations of tongue	0.003	0.997	0.000
Q38.2 Macroglossia	0.003	0.997	0.000
Q38.1 Ankyloglossia	0.003	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
M54.12 Radiculopathy (Cervical region)	0.003	0.997	0.000
Q54 Hypospadias	0.003	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
T42.0 Hydantoin derivatives	0.003	0.997	0.000
Q54.9 Hypospadias, unspecified	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.003	0.997	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.003	0.997	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.997	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.997	0.000
Q40.1 Congenital hiatus hernia	0.002	0.997	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.997	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.003	0.997	0.000
F43.2 Adjustment disorders	0.003	0.997	0.000
N28.0 Ischaemia and infarction of kidney	0.003	0.997	0.000
N70.1 Chronic salpingitis and oophoritis	0.000	0.997	0.003
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.003	0.997	0.000
Q25.1 Coarctation of aorta	0.003	0.997	0.000
Q80-Q89 Other congenital malformations	0.003	0.997	0.000
Q45.8 Other specified congenital malformations of digestive system	0.002	0.997	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.000	0.997	0.002
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.997	0.003
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.002	0.997	0.000
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.997	0.003
M54.17 Radiculopathy (Lumbosacral region)	0.002	0.997	0.000
M47 Spondylosis	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.997	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.997	0.000
Q45.1 Annular pancreas	0.002	0.997	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.997	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.003	0.997	0.000
M54.19 Radiculopathy (Site unspecified)	0.002	0.997	0.000
Q54.0 Hypospadias, balanic	0.002	0.997	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.003	0.997	0.000
J09-J18 Influenza and pneumonia	0.003	0.997	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.002	0.997	0.000
Q25.4 Other congenital malformations of aorta	0.002	0.997	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.997	0.000
Q27.3 Peripheral arteriovenous malformation	0.002	0.997	0.000
Z47 Other orthopaedic follow-up care	0.000	0.997	0.003
Q25.9 Congenital malformation of great arteries, unspecified	0.002	0.997	0.000
Q25.8 Other congenital malformations of great arteries	0.002	0.997	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.002	0.997	0.000
Q25.6 Stenosis of pulmonary artery	0.002	0.997	0.000
Q25.5 Atresia of pulmonary artery	0.002	0.997	0.000
Q25.3 Stenosis of aorta	0.002	0.997	0.000
Q25.2 Atresia of aorta	0.002	0.997	0.000
Z47.9 Orthopaedic follow-up care, unspecified	0.000	0.997	0.002
Q39 Congenital malformations of oesophagus	0.002	0.997	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
Q54.1 Hypospadias, penile	0.002	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
N50.1 Vascular disorders of male genital organs	0.000	0.998	0.002
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
Q05 Spina bifida	0.002	0.998	0.000
Q26 Congenital malformations of great veins	0.002	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.002	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.002	0.998	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.002	0.998	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.002	0.998	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.002	0.998	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.002	0.998	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.002	0.998	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.002	0.998	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.002	0.998	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.002	0.998	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.002	0.998	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.002	0.998	0.000
C05 Malignant neoplasm of palate	0.002	0.998	0.000
Q82 Other congenital malformations of skin	0.002	0.998	0.000
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
Q82.5 Congenital nonneoplastic naevus	0.002	0.998	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.002	0.998	0.000
D68.9 Coagulation defect, unspecified	0.002	0.998	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.002	0.998	0.000
C05.1 Soft palate	0.002	0.998	0.000
J15.1 Pneumonia due to Pseudomonas	0.002	0.998	0.000
M06.9 Rheumatoid arthritis, unspecified	0.002	0.998	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.002	0.998	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.002	0.998	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.002	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.002	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.002	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
Q27.4 Congenital phlebectasia	0.002	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.002	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.002	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.998	0.000
Q54.8 Other hypospadias	0.002	0.998	0.000
Q54.4 Congenital chordee	0.002	0.998	0.000
Q54.3 Hypospadias, perineal	0.002	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.998	0.000
R60.9 Oedema, unspecified	0.002	0.998	0.000
C12 Malignant neoplasm of pyriform sinus	0.002	0.998	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.002	0.998	0.000
J10 Influenza due to identified influenza virus	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.002	0.998	0.000
H43.8 Other disorders of vitreous body	0.002	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.998	0.000
C10 Malignant neoplasm of oropharynx	0.002	0.998	0.000
C00 Malignant neoplasm of lip	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.998	0.002
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.002	0.998	0.000
Q24.0 Dextrocardia	0.002	0.998	0.000
R60 Oedema, not elsewhere classified	0.002	0.998	0.000
Q24.6 Congenital heart block	0.002	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.998	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.998	0.000
Q24.2 Cor triatriatum	0.002	0.998	0.000
Q24.1 Levocardia	0.002	0.998	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.002	0.998	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.002	0.998	0.000
N41.0 Acute prostatitis	0.000	0.998	0.002
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.998	0.000
Q84 Other congenital malformations of integument	0.002	0.998	0.000
Q81 Epidermolysis bullosa	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.002	0.998	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
Q82.0 Hereditary lymphoedema	0.002	0.998	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.002	0.998	0.000
C03 Malignant neoplasm of gum	0.002	0.998	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.002	0.998	0.000
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
Q07 Other congenital malformations of nervous system	0.002	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.998	0.000
Q04 Other congenital malformations of brain	0.002	0.998	0.000
Q03 Congenital hydrocephalus	0.002	0.998	0.000
Q01 Encephalocele	0.002	0.998	0.000
Q00 Anencephaly and similar malformations	0.002	0.998	0.000
Q02 Microcephaly	0.002	0.998	0.000
J16.8 Pneumonia due to other specified infectious organisms	0.002	0.998	0.000
L57.5 Actinic granuloma	0.002	0.998	0.000
L57.3 Poikiloderma of Civatte	0.002	0.998	0.000
L57.2 Cutis rhomboidalis nuchae	0.002	0.998	0.000
L57.1 Actinic reticuloid	0.002	0.998	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.002	0.998	0.000
C13 Malignant neoplasm of hypopharynx	0.002	0.998	0.000
J09 Influenza due to certain identified influenza virus	0.002	0.998	0.000
H60.1 Cellulitis of external ear	0.002	0.998	0.000
Q55.6 Other congenital malformations of penis	0.002	0.998	0.000
C09 Malignant neoplasm of tonsil	0.002	0.998	0.000
C00.0 External upper lip	0.002	0.998	0.000
C10.9 Oropharynx, unspecified	0.002	0.998	0.000
J92.9 Pleural plaque without asbestos	0.002	0.998	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.002	0.998	0.000
Q39.8 Other congenital malformations of oesophagus	0.002	0.998	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.998	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.002	0.998	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.002	0.998	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.002	0.998	0.000
Q39.0 Atresia of oesophagus without fistula	0.002	0.998	0.000
S41.1 Open wound of upper arm	0.002	0.998	0.000
C04 Malignant neoplasm of floor of mouth	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
Q82.2 Mastocytosis	0.002	0.998	0.000
Q44.7 Other congenital malformations of liver	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
Q44.4 Choledochal cyst	0.002	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.998	0.000
Q44.2 Atresia of bile ducts	0.002	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.002	0.998	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.002	0.998	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.002	0.998	0.000
C05.9 Palate, unspecified	0.002	0.998	0.000
C05.8 Overlapping lesion of palate	0.002	0.998	0.000
C05.2 Uvula	0.002	0.998	0.000
C05.0 Hard palate	0.002	0.998	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.002	0.998	0.000
L57.4 Cutis laxa senilis	0.002	0.998	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.002	0.998	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
Q20.6 Isomerism of atrial appendages	0.002	0.998	0.000
Q20.5 Discordant atrioventricular connexion	0.002	0.998	0.000
Q20.4 Double inlet ventricle	0.002	0.998	0.000
Q20.3 Discordant ventriculoarterial connexion	0.002	0.998	0.000
Q20.2 Double outlet left ventricle	0.002	0.998	0.000
Q20.1 Double outlet right ventricle	0.002	0.998	0.000
Q20.0 Common arterial trunk	0.002	0.998	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.002	0.998	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.002	0.998	0.000
Q22.6 Hypoplastic right heart syndrome	0.002	0.998	0.000
Q22.5 Ebstein's anomaly	0.002	0.998	0.000
Q22.4 Congenital tricuspid stenosis	0.002	0.998	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.002	0.998	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.002	0.998	0.000
Q22.1 Congenital pulmonary valve stenosis	0.002	0.998	0.000
Q22.0 Pulmonary valve atresia	0.002	0.998	0.000
Q23.1 Congenital insufficiency of aortic valve	0.002	0.998	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.998	0.000
Q26.8 Other congenital malformations of great veins	0.002	0.998	0.000
Q26.6 Portal vein-hepatic artery fistula	0.002	0.998	0.000
Q26.5 Anomalous portal venous connexion	0.002	0.998	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.998	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.002	0.998	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.002	0.998	0.000
Q26.1 Persistent left superior vena cava	0.002	0.998	0.000
Q26.0 Congenital stenosis of vena cava	0.002	0.998	0.000
Q82.9 Congenital malformation of skin, unspecified	0.002	0.998	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.002	0.998	0.000
Q82.3 Incontinentia pigmenti	0.002	0.998	0.000
Q82.1 Xeroderma pigmentosum	0.002	0.998	0.000
T42.1 Iminostilbenes	0.002	0.998	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.002	0.998	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.998	0.000
Q39.6 Diverticulum of oesophagus	0.002	0.998	0.000
S41.0 Open wound of shoulder	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
C02.1 Border of tongue	0.002	0.998	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.998	0.002
L60.9 Nail disorder, unspecified	0.002	0.998	0.000
C07 Malignant neoplasm of parotid gland	0.002	0.998	0.000
C11 Malignant neoplasm of nasopharynx	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
M47.2 Other spondylosis with radiculopathy	0.002	0.998	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
J12 Viral pneumonia, not elsewhere classified	0.002	0.998	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
C10.8 Overlapping lesion of oropharynx	0.002	0.998	0.000
C10.4 Branchial cleft	0.002	0.998	0.000
C10.3 Posterior wall of oropharynx	0.002	0.998	0.000
C10.2 Lateral wall of oropharynx	0.002	0.998	0.000
C10.1 Anterior surface of epiglottis	0.002	0.998	0.000
C10.0 Vallecula	0.002	0.998	0.000
J10.8 Influenza with other manifestations, influenza virus identified	0.002	0.998	0.000
J16.0 Chlamydial pneumonia	0.002	0.998	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.998	0.000
Q33 Congenital malformations of lung	0.002	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.002	0.998	0.000
Q30 Congenital malformations of nose	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
Q36 Cleft lip	0.002	0.998	0.000
Q35 Cleft palate	0.002	0.998	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.002	0.998	0.000
C00.9 Lip, unspecified	0.002	0.998	0.000
C00.8 Overlapping lesion of lip	0.002	0.998	0.000
C00.6 Commissure of lip	0.002	0.998	0.000
C00.5 Lip, unspecified, inner aspect	0.002	0.998	0.000
C00.4 Lower lip, inner aspect	0.002	0.998	0.000
C00.3 Upper lip, inner aspect	0.002	0.998	0.000
C00.2 External lip, unspecified	0.002	0.998	0.000
C00.1 External lower lip	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
Q90 Down's syndrome	0.002	0.998	0.000
S41 Open wound of shoulder and upper arm	0.002	0.998	0.000
C08.0 Submandibular gland	0.002	0.998	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.998	0.000
Q55.3 Atresia of vas deferens	0.002	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.998	0.000
Q55.0 Absence and aplasia of testis	0.002	0.998	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.002	0.998	0.000
U80.1 Methicillin resistant agent	0.000	0.998	0.002
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
C03.1 Lower gum	0.002	0.998	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.002	0.998	0.000
J15.5 Pneumonia due to Escherichia coli	0.002	0.998	0.000
J15.3 Pneumonia due to streptococcus, group B	0.002	0.998	0.000
J15.2 Pneumonia due to staphylococcus	0.002	0.998	0.000
M47.1 Other spondylosis with myelopathy	0.002	0.998	0.000
Q60.0 Renal agenesis, unilateral	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
N48.4 Impotence of organic origin	0.000	0.998	0.002
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Q80.9 Congenital ichthyosis, unspecified	0.002	0.998	0.000
Q80.8 Other congenital ichthyosis	0.002	0.998	0.000
Q80.4 Harlequin foetus	0.002	0.998	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.002	0.998	0.000
Q80.2 Lamellar ichthyosis	0.002	0.998	0.000
Q80.1 X-linked ichthyosis	0.002	0.998	0.000
Q80.0 Ichthyosis vulgaris	0.002	0.998	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.002	0.998	0.000
Q81.8 Other epidermolysis bullosa	0.002	0.998	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.002	0.998	0.000
Q81.1 Epidermolysis bullosa letalis	0.002	0.998	0.000
Q81.0 Epidermolysis bullosa simplex	0.002	0.998	0.000
Q84.9 Congenital malformation of integument, unspecified	0.002	0.998	0.000
Q84.8 Other specified congenital malformations of integument	0.002	0.998	0.000
Q84.6 Other congenital malformations of nails	0.002	0.998	0.000
Q84.5 Enlarged and hypertrophic nails	0.002	0.998	0.000
Q84.4 Congenital leukonychia	0.002	0.998	0.000
Q84.3 Anonychia	0.002	0.998	0.000
Q84.2 Other congenital malformations of hair	0.002	0.998	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.002	0.998	0.000
Q84.0 Congenital alopecia	0.002	0.998	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.002	0.998	0.000
Q86.2 Dysmorphism due to warfarin	0.002	0.998	0.000
Q86.1 Foetal hydantoin syndrome	0.002	0.998	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.002	0.998	0.000
Z71.8 Other specified counselling	0.000	0.998	0.002
C03.9 Gum, unspecified	0.002	0.998	0.000
C03.0 Upper gum	0.002	0.998	0.000
C08.8 Overlapping lesion of major salivary glands	0.002	0.998	0.000
C08.1 Sublingual gland	0.002	0.998	0.000
S40.0 Contusion of shoulder and upper arm	0.002	0.998	0.000
S82.6 Fracture of lateral malleolus	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
M06.34 Rheumatoid nodule (Hand)	0.002	0.998	0.000
J15.9 Bacterial pneumonia, unspecified	0.002	0.998	0.000
J15.8 Other bacterial pneumonia	0.002	0.998	0.000
Q00.2 Iniencephaly	0.002	0.998	0.000
Q00.1 Craniorachischisis	0.002	0.998	0.000
Q00.0 Anencephaly	0.002	0.998	0.000
Q01.9 Encephalocele, unspecified	0.002	0.998	0.000
Q01.8 Encephalocele of other sites	0.002	0.998	0.000
Q01.2 Occipital encephalocele	0.002	0.998	0.000
Q01.1 Nasofrontal encephalocele	0.002	0.998	0.000
Q01.0 Frontal encephalocele	0.002	0.998	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.002	0.998	0.000
Q03.8 Other congenital hydrocephalus	0.002	0.998	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.002	0.998	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.002	0.998	0.000
Q04.9 Congenital malformation of brain, unspecified	0.002	0.998	0.000
Q04.8 Other specified congenital malformations of brain	0.002	0.998	0.000
Q04.5 Megalencephaly	0.002	0.998	0.000
Q04.4 Septo-optic dysplasia	0.002	0.998	0.000
Q04.3 Other reduction deformities of brain	0.002	0.998	0.000
Q04.2 Holoprosencephaly	0.002	0.998	0.000
Q04.1 Arhinencephaly	0.002	0.998	0.000
Q04.0 Congenital malformations of corpus callosum	0.002	0.998	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.002	0.998	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.002	0.998	0.000
Q06.4 Hydromyelia	0.002	0.998	0.000
Q06.3 Other congenital cauda equina malformations	0.002	0.998	0.000
Q06.2 Diastematomyelia	0.002	0.998	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.002	0.998	0.000
Q06.0 Amyelia	0.002	0.998	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.002	0.998	0.000
Q07.8 Other specified congenital malformations of nervous system	0.002	0.998	0.000
Q14.1 Congenital malformation of retina	0.002	0.998	0.000
R60.1 Generalised oedema	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.002	0.998	0.000
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.002	0.998	0.000
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.002	0.998	0.000
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.002	0.998	0.000
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.002	0.998	0.000
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)	0.002	0.998	0.000
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)	0.002	0.998	0.000
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)	0.002	0.998	0.000
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)	0.002	0.998	0.000
C08.9 Major salivary gland, unspecified	0.002	0.998	0.000
C13.9 Hypopharynx, unspecified	0.002	0.998	0.000
C13.8 Overlapping lesion of hypopharynx	0.002	0.998	0.000
C13.2 Posterior wall of hypopharynx	0.002	0.998	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.002	0.998	0.000
C13.0 Postcricoid region	0.002	0.998	0.000
J38.1 Polyp of vocal cord and larynx	0.002	0.998	0.000
Q04.6 Congenital cerebral cysts	0.002	0.998	0.000
Q07.0 Arnold-Chiari syndrome	0.002	0.998	0.000
J18 Pneumonia, organism unspecified	0.002	0.998	0.000
J17 Pneumonia in diseases classified elsewhere	0.002	0.998	0.000
C06.2 Retromolar area	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations