TreeWAS – Variant ID: rs16999165

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S00-S09 Injuries to the head	0.618	0.382	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.604	0.396	0.000
S02 Fracture of skull and facial bones	0.604	0.396	0.000
S01 Open wound of head	0.602	0.398	0.000
S40-S49 Injuries to the shoulder and upper arm	0.558	0.442	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.554	0.446	0.000
S60-S69 Injuries to the wrist and hand	0.551	0.449	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.549	0.451	0.000
S50-S59 Injuries to the elbow and forearm	0.546	0.454	0.000
S02.3 Fracture of orbital floor	0.541	0.459	0.000
S01.0 Open wound of scalp	0.539	0.461	0.000
S05 Injury of eye and orbit	0.534	0.466	0.000
S02.6 Fracture of mandible	0.523	0.477	0.000
S42 Fracture of shoulder and upper arm	0.518	0.482	0.000
K59.0 Constipation	0.000	0.494	0.506
S01.5 Open wound of lip and oral cavity	0.505	0.495	0.000
S02.8 Fractures of other skull and facial bones	0.505	0.495	0.000
S01.8 Open wound of other parts of head	0.505	0.495	0.000
S02.4 Fracture of malar and maxillary bones	0.503	0.497	0.000
K59 Other functional intestinal disorders	0.000	0.500	0.500
K55-K64 Other diseases of intestines	0.000	0.503	0.497
S02.30 Fracture of orbital floor (closed)	0.497	0.503	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.000	0.504	0.496
S61 Open wound of wrist and hand	0.490	0.510	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.489	0.511	0.000
S52 Fracture of forearm	0.488	0.512	0.000
S01.1 Open wound of eyelid and periocular area	0.487	0.513	0.000
K56.6 Other and unspecified intestinal obstruction	0.000	0.519	0.481
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.477	0.523	0.000
T90 Sequelae of injuries of head	0.476	0.524	0.000
S05.1 Contusion of eyeball and orbital tissues	0.473	0.526	0.000
T98 Sequelae of other and unspecified effects of external causes	0.469	0.531	0.000
S20-S29 Injuries to the thorax	0.469	0.531	0.000
S42.2 Fracture of upper end of humerus	0.468	0.532	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.468	0.532	0.000
S00 Superficial injury of head	0.466	0.534	0.000
S61.0 Open wound of finger(s) without damage to nail	0.466	0.534	0.000
S02.60 Fracture of mandible (closed)	0.466	0.534	0.000
K55 Vascular disorders of intestine	0.000	0.537	0.463
S70-S79 Injuries to the hip and thigh	0.463	0.537	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.459	0.541	0.000
S06 Intracranial injury	0.458	0.542	0.000
T66-T78 Other and unspecified effects of external causes	0.457	0.543	0.000
S01.2 Open wound of nose	0.454	0.545	0.000
T43.2 Other and unspecified antidepressants	0.453	0.547	0.000
S40 Superficial injury of shoulder and upper arm	0.451	0.549	0.000
S02.1 Fracture of base of skull	0.450	0.550	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.000	0.550	0.450
S02.0 Fracture of vault of skull	0.449	0.551	0.000
S01.9 Open wound of head, part unspecified	0.449	0.551	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.444	0.556	0.000
S08 Traumatic amputation of part of head	0.443	0.557	0.000
S07 Crushing injury of head	0.443	0.557	0.000
S04 Injury of cranial nerves	0.443	0.557	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.443	0.557	0.000
Chapter XI Diseases of the digestive system	0.000	0.559	0.441
S65 Injury of blood vessels at wrist and hand level	0.439	0.561	0.000
K65-K67 Diseases of peritoneum	0.000	0.564	0.436
S02.80 Fractures of other skull and facial bones (closed)	0.434	0.565	0.000
S67 Crushing injury of wrist and hand	0.433	0.567	0.000
S42.20 Fracture of upper end of humerus (closed)	0.433	0.567	0.000
T33-T35 Frostbite	0.433	0.567	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.433	0.567	0.000
T00-T07 Injuries involving multiple body regions	0.433	0.567	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.433	0.567	0.000
S02.7 Multiple fractures involving skull and facial bones	0.433	0.567	0.000
S10-S19 Injuries to the neck	0.433	0.567	0.000
S01.7 Multiple open wounds of head	0.432	0.568	0.000
S01.4 Open wound of cheek and temporomandibular area	0.432	0.568	0.000
K66.0 Peritoneal adhesions	0.000	0.570	0.430
S02.40 Fracture of malar and maxillary bones (closed)	0.430	0.570	0.000
K66 Other disorders of peritoneum	0.000	0.570	0.430
S51 Open wound of forearm	0.429	0.571	0.000
K56.2 Volvulus	0.000	0.572	0.428
K59.3 Megacolon, not elsewhere classified	0.000	0.574	0.426
S69 Other and unspecified injuries of wrist and hand	0.426	0.574	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.426	0.574	0.000
S62 Fracture at wrist and hand level	0.425	0.574	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.575	0.425
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.422	0.578	0.000
S52.7 Multiple fractures of forearm	0.419	0.581	0.000
S02.5 Fracture of tooth	0.417	0.583	0.000
K63 Other diseases of intestine	0.000	0.583	0.417
T92 Sequelae of injuries of upper limb	0.416	0.584	0.000
S42.3 Fracture of shaft of humerus	0.416	0.584	0.000
S01.3 Open wound of ear	0.416	0.584	0.000
T93 Sequelae of injuries of lower limb	0.413	0.587	0.000
S64 Injury of nerves at wrist and hand level	0.412	0.588	0.000
S56 Injury of muscle and tendon at forearm level	0.412	0.588	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.412	0.588	0.000
S60 Superficial injury of wrist and hand	0.411	0.589	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.408	0.592	0.000
S52.0 Fracture of upper end of ulna	0.405	0.595	0.000
S02.2 Fracture of nasal bones	0.405	0.595	0.000
S09 Other and unspecified injuries of head	0.404	0.596	0.000
K50-K52 Noninfective enteritis and colitis	0.000	0.596	0.404
K55.9 Vascular disorder of intestine, unspecified	0.000	0.596	0.404
S32 Fracture of lumbar spine and pelvis	0.402	0.598	0.000
T79-T79 Certain early complications of trauma	0.402	0.598	0.000
S48 Traumatic amputation of shoulder and upper arm	0.400	0.600	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.400	0.600	0.000
S44 Injury of nerves at shoulder and upper arm level	0.400	0.600	0.000
S41 Open wound of shoulder and upper arm	0.400	0.600	0.000
S47 Crushing injury of shoulder and upper arm	0.400	0.600	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.398	0.602	0.000
S52.6 Fracture of lower end of both ulna and radius	0.398	0.602	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.398	0.602	0.000
T95 Sequelae of burns, corrosions and frostbite	0.397	0.603	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.397	0.603	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.397	0.603	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.397	0.603	0.000
K61 Abscess of anal and rectal regions	0.000	0.603	0.397
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.396	0.604	0.000
K83 Other diseases of biliary tract	0.000	0.604	0.396
K86 Other diseases of pancreas	0.000	0.605	0.395
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.394	0.606	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.394	0.606	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.394	0.606	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.394	0.606	0.000
T36 Poisoning by systemic antibiotics	0.394	0.606	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.393	0.607	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.392	0.608	0.000
K55.0 Acute vascular disorders of intestine	0.000	0.608	0.392
S59 Other and unspecified injuries of forearm	0.391	0.609	0.000
S58 Traumatic amputation of forearm	0.391	0.609	0.000
S57 Crushing injury of forearm	0.391	0.609	0.000
S55 Injury of blood vessels at forearm level	0.391	0.609	0.000
S54 Injury of nerves at forearm level	0.391	0.609	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.391	0.609	0.000
S02.31 Fracture of orbital floor (open)	0.388	0.612	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.388	0.612	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.387	0.613	0.000
T90.9 Sequelae of unspecified injury of head	0.386	0.614	0.000
K63.8 Other specified diseases of intestine	0.000	0.614	0.386
K51 Ulcerative colitis	0.000	0.614	0.386
T91 Sequelae of injuries of neck and trunk	0.386	0.614	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.385	0.615	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.384	0.615	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.384	0.615	0.000
S05.9 Injury of eye and orbit, part unspecified	0.383	0.617	0.000
S05.8 Other injuries of eye and orbit	0.383	0.617	0.000
S05.7 Avulsion of eye	0.383	0.617	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.383	0.617	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.383	0.617	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.383	0.617	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.383	0.617	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.383	0.617	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.383	0.617	0.000
K56.7 Ileus, unspecified	0.000	0.619	0.381
S00.1 Contusion of eyelid and periocular area	0.380	0.620	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.379	0.621	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.378	0.622	0.000
K63.1 Perforation of intestine (nontraumatic)	0.000	0.622	0.378
S42.1 Fracture of scapula	0.377	0.623	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.377	0.623	0.000
K58 Irritable bowel syndrome	0.000	0.624	0.376
S42.4 Fracture of lower end of humerus	0.375	0.624	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.375	0.624	0.000
S02.61 Fracture of mandible (open)	0.375	0.625	0.000
S50 Superficial injury of forearm	0.375	0.625	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.371	0.629	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.371	0.629	0.000
T23 Burn and corrosion of wrist and hand	0.370	0.630	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.369	0.631	0.000
S52.70 Multiple fractures of forearm (closed)	0.369	0.631	0.000
S00.7 Multiple superficial injuries of head	0.369	0.631	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.368	0.632	0.000
S42.0 Fracture of clavicle	0.367	0.633	0.000
S00.0 Superficial injury of scalp	0.366	0.634	0.000
K83.1 Obstruction of bile duct	0.000	0.635	0.365
K55.2 Angiodysplasia of colon	0.000	0.635	0.365
S61.7 Multiple open wounds of wrist and hand	0.365	0.635	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.364	0.635	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.636	0.364
S02.81 Fractures of other skull and facial bones (open)	0.362	0.638	0.000
S52.2 Fracture of shaft of ulna	0.361	0.639	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.360	0.639	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.360	0.640	0.000
S29 Other and unspecified injuries of thorax	0.359	0.640	0.000
S52.1 Fracture of upper end of radius	0.359	0.641	0.000
K59.9 Functional intestinal disorder, unspecified	0.000	0.641	0.359
K59.4 Anal spasm	0.000	0.641	0.359
K59.2 Neurogenic bowel, not elsewhere classified	0.000	0.641	0.359
S00.5 Superficial injury of lip and oral cavity	0.358	0.642	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.358	0.642	0.000
S68 Traumatic amputation of wrist and hand	0.357	0.643	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.357	0.643	0.000
K64 Haemorrhoids and perianal venous thrombosis	0.000	0.643	0.357
K56.3 Gallstone ileus	0.000	0.644	0.356
K56.0 Paralytic ileus	0.000	0.644	0.356
T46.4 Angiotensin-converting-enzyme inhibitors	0.355	0.645	0.000
K86.8 Other specified diseases of pancreas	0.000	0.645	0.355
S90-S99 Injuries to the ankle and foot	0.354	0.646	0.000
S27 Injury of other and unspecified intrathoracic organs	0.354	0.646	0.000
S71 Open wound of hip and thigh	0.354	0.646	0.000
T78 Adverse effects, not elsewhere classified	0.352	0.648	0.000
T90.4 Sequelae of injury of eye and orbit	0.351	0.648	0.000
T43.9 Psychotropic drug, unspecified	0.351	0.649	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.351	0.649	0.000
T43.6 Psychostimulants with abuse potential	0.351	0.649	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.351	0.649	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.351	0.649	0.000
S52.9 Fracture of forearm, part unspecified	0.350	0.650	0.000
S52.8 Fracture of other parts of forearm	0.350	0.650	0.000
S52.4 Fracture of shafts of both ulna and radius	0.350	0.650	0.000
S52.3 Fracture of shaft of radius	0.350	0.650	0.000
S06.8 Other intracranial injuries	0.350	0.650	0.000
K65 Peritonitis	0.000	0.650	0.350
S80-S89 Injuries to the knee and lower leg	0.349	0.651	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.349	0.651	0.000
S06.3 Focal brain injury	0.348	0.652	0.000
S00.3 Superficial injury of nose	0.348	0.652	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.652	0.348
T93.9 Sequelae of unspecified injury of lower limb	0.347	0.653	0.000
K85 Acute pancreatitis	0.000	0.653	0.347
S70 Superficial injury of hip and thigh	0.346	0.653	0.000
K61.0 Anal abscess	0.000	0.654	0.346
S52.00 Fracture of upper end of ulna (closed)	0.346	0.654	0.000
K56.4 Other impaction of intestine	0.000	0.654	0.345
K70-K77 Diseases of liver	0.000	0.655	0.345
S62.6 Fracture of other finger	0.345	0.655	0.000
S42.30 Fracture of shaft of humerus (closed)	0.343	0.657	0.000
K59.1 Functional diarrhoea	0.000	0.658	0.342
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.342	0.658	0.000
S37 Injury of urinary and pelvic organs	0.342	0.658	0.000
S36 Injury of intra-abdominal organs	0.342	0.658	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.342	0.658	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.342	0.658	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.342	0.658	0.000
S31 Open wound of abdomen, lower back and pelvis	0.342	0.658	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.342	0.658	0.000
T90.8 Sequelae of other specified injuries of head	0.341	0.659	0.000
T90.5 Sequelae of intracranial injury	0.341	0.659	0.000
T90.3 Sequelae of injury of cranial nerves	0.341	0.659	0.000
T90.1 Sequelae of open wound of head	0.341	0.659	0.000
T90.0 Sequelae of superficial injury of head	0.341	0.659	0.000
S51.0 Open wound of elbow	0.341	0.659	0.000
S02.10 Fracture of base of skull (closed)	0.340	0.660	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.339	0.661	0.000
S02.00 Fracture of vault of skull (closed)	0.338	0.662	0.000
T98.2 Sequelae of certain early complications of trauma	0.336	0.663	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.336	0.663	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.336	0.663	0.000
S69.9 Unspecified injury of wrist and hand	0.336	0.664	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.336	0.664	0.000
S26 Injury of heart	0.336	0.664	0.000
S25 Injury of blood vessels of thorax	0.336	0.664	0.000
S24 Injury of nerves and spinal cord at thorax level	0.336	0.664	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.336	0.664	0.000
S21 Open wound of thorax	0.336	0.664	0.000
S42.21 Fracture of upper end of humerus (open)	0.336	0.664	0.000
T25 Burn and corrosion of ankle and foot	0.335	0.665	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.335	0.665	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.335	0.665	0.000
T21 Burn and corrosion of trunk	0.335	0.665	0.000
T20 Burn and corrosion of head and neck	0.335	0.665	0.000
S00.4 Superficial injury of ear	0.334	0.665	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.334	0.665	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.333	0.666	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.333	0.667	0.000
K55.8 Other vascular disorders of intestine	0.000	0.668	0.332
K55.1 Chronic vascular disorders of intestine	0.000	0.668	0.332
S79 Other and unspecified injuries of hip and thigh	0.332	0.668	0.000
S78 Traumatic amputation of hip and thigh	0.332	0.668	0.000
S77 Crushing injury of hip and thigh	0.332	0.668	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.332	0.668	0.000
S75 Injury of blood vessels at hip and thigh level	0.332	0.668	0.000
S74 Injury of nerves at hip and thigh level	0.332	0.668	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.330	0.669	0.000
S60.8 Other superficial injuries of wrist and hand	0.330	0.670	0.000
S06.2 Diffuse brain injury	0.329	0.670	0.000
K83.0 Cholangitis	0.000	0.671	0.329
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.329	0.671	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.329	0.671	0.000
T46.7 Peripheral vasodilators	0.329	0.671	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.329	0.671	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.329	0.671	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.329	0.671	0.000
T46.1 Calcium-channel blockers	0.329	0.671	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.329	0.671	0.000
S61.8 Open wound of other parts of wrist and hand	0.329	0.671	0.000
S06.9 Intracranial injury, unspecified	0.328	0.671	0.000
S06.7 Intracranial injury with prolonged coma	0.328	0.671	0.000
S06.4 Epidural haemorrhage	0.328	0.671	0.000
S06.1 Traumatic cerebral oedema	0.328	0.671	0.000
S06.5 Traumatic subdural haemorrhage	0.328	0.671	0.000
T75 Effects of other external causes	0.328	0.672	0.000
T74 Maltreatment syndromes	0.328	0.672	0.000
T73 Effects of other deprivation	0.328	0.672	0.000
T70 Effects of air pressure and water pressure	0.328	0.672	0.000
T69 Other effects of reduced temperature	0.328	0.672	0.000
T67 Effects of heat and light	0.328	0.672	0.000
T71 Asphyxiation	0.328	0.672	0.000
T68 Hypothermia	0.328	0.672	0.000
T66 Unspecified effects of radiation	0.328	0.672	0.000
S06.0 Concussion	0.327	0.672	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.673	0.327
S09.8 Other specified injuries of head	0.327	0.673	0.000
S32.1 Fracture of sacrum	0.326	0.673	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.326	0.674	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.324	0.676	0.000
S40.0 Contusion of shoulder and upper arm	0.324	0.676	0.000
S02.11 Fracture of base of skull (open)	0.323	0.677	0.000
S64.3 Injury of digital nerve of thumb	0.322	0.678	0.000
S02.01 Fracture of vault of skull (open)	0.322	0.678	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.321	0.678	0.000
K76 Other diseases of liver	0.000	0.679	0.321
K51.8 Other ulcerative colitis	0.000	0.680	0.320
S62.4 Multiple fractures of metacarpal bones	0.319	0.681	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.319	0.681	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.319	0.681	0.000
T47.7 Emetics	0.319	0.681	0.000
T47.6 Antidiarrhoeal drugs	0.319	0.681	0.000
T47.5 Digestants	0.319	0.681	0.000
T47.4 Other laxatives	0.319	0.681	0.000
T47.3 Saline and osmotic laxatives	0.319	0.681	0.000
T47.2 Stimulant laxatives	0.319	0.681	0.000
T47.0 Histamine H(2)-receptor antagonists	0.319	0.681	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.318	0.682	0.000
S03.4 Sprain and strain of jaw	0.318	0.682	0.000
S03.3 Dislocation of other and unspecified parts of head	0.318	0.682	0.000
S03.2 Dislocation of tooth	0.318	0.682	0.000
S03.1 Dislocation of septal cartilage of nose	0.318	0.682	0.000
S03.0 Dislocation of jaw	0.318	0.682	0.000
S04.9 Injury of unspecified cranial nerve	0.318	0.682	0.000
S04.8 Injury of other cranial nerves	0.318	0.682	0.000
S04.7 Injury of accessory nerve	0.318	0.682	0.000
S04.6 Injury of acoustic nerve	0.318	0.682	0.000
S04.5 Injury of facial nerve	0.318	0.682	0.000
S04.4 Injury of abducent nerve	0.318	0.682	0.000
S04.3 Injury of trigeminal nerve	0.318	0.682	0.000
S04.2 Injury of trochlear nerve	0.318	0.682	0.000
S04.1 Injury of oculomotor nerve	0.318	0.682	0.000
S04.0 Injury of optic nerve and pathways	0.318	0.682	0.000
S07.9 Crushing injury of head, part unspecified	0.318	0.682	0.000
S07.8 Crushing injury of other parts of head	0.318	0.682	0.000
S07.1 Crushing injury of skull	0.318	0.682	0.000
S07.0 Crushing injury of face	0.318	0.682	0.000
S08.9 Traumatic amputation of unspecified part of head	0.318	0.682	0.000
S08.8 Traumatic amputation of other parts of head	0.318	0.682	0.000
S08.1 Traumatic amputation of ear	0.318	0.682	0.000
S08.0 Avulsion of scalp	0.318	0.682	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.683	0.317
S64.2 Injury of radial nerve at wrist and hand level	0.317	0.683	0.000
S32.5 Fracture of pubis	0.317	0.683	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.316	0.684	0.000
K50.0 Crohn's disease of small intestine	0.000	0.685	0.315
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.315	0.685	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.315	0.685	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.315	0.685	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.315	0.685	0.000
S65.5 Injury of blood vessel(s) of other finger	0.315	0.685	0.000
S65.4 Injury of blood vessel(s) of thumb	0.315	0.685	0.000
S65.3 Injury of deep palmar arch	0.315	0.685	0.000
S65.2 Injury of superficial palmar arch	0.315	0.685	0.000
S65.1 Injury of radial artery at wrist and hand level	0.315	0.685	0.000
S32.0 Fracture of lumbar vertebra	0.315	0.685	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.314	0.685	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.313	0.687	0.000
S51.9 Open wound of forearm, part unspecified	0.313	0.687	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.688	0.312
T78.2 Anaphylactic shock, unspecified	0.312	0.688	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.312	0.688	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.312	0.688	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.311	0.689	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.311	0.689	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.310	0.689	0.000
T05 Traumatic amputations involving multiple body regions	0.310	0.689	0.000
T04 Crushing injuries involving multiple body regions	0.310	0.689	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.310	0.689	0.000
T02 Fractures involving multiple body regions	0.310	0.689	0.000
T01 Open wounds involving multiple body regions	0.310	0.689	0.000
T00 Superficial injuries involving multiple body regions	0.310	0.689	0.000
T07 Unspecified multiple injuries	0.310	0.689	0.000
T28 Burn and corrosion of other internal organs	0.310	0.689	0.000
T27 Burn and corrosion of respiratory tract	0.310	0.689	0.000
T26 Burn and corrosion confined to eye and adnexa	0.310	0.689	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.310	0.689	0.000
T34 Frostbite with tissue necrosis	0.310	0.689	0.000
T33 Superficial frostbite	0.310	0.689	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.310	0.689	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.310	0.689	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.310	0.689	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.310	0.689	0.000
S19 Other and unspecified injuries of neck	0.310	0.689	0.000
S17 Crushing injury of neck	0.310	0.689	0.000
S15 Injury of blood vessels at neck level	0.310	0.689	0.000
S14 Injury of nerves and spinal cord at neck level	0.310	0.689	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.310	0.689	0.000
S11 Open wound of neck	0.310	0.689	0.000
S10 Superficial injury of neck	0.310	0.689	0.000
S18 Traumatic amputation at neck level	0.310	0.689	0.000
S16 Injury of muscle and tendon at neck level	0.310	0.689	0.000
K86.2 Cyst of pancreas	0.000	0.689	0.311
S12 Fracture of neck	0.310	0.690	0.000
S62.2 Fracture of first metacarpal bone	0.308	0.691	0.000
K66.9 Disorder of peritoneum, unspecified	0.000	0.692	0.308
K66.1 Haemoperitoneum	0.000	0.692	0.308
S51.8 Open wound of other parts of forearm	0.307	0.692	0.000
S51.7 Multiple open wounds of forearm	0.307	0.692	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.307	0.693	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.307	0.693	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.307	0.693	0.000
K56.1 Intussusception	0.000	0.694	0.306
S69.8 Other specified injuries of wrist and hand	0.305	0.694	0.000
S69.7 Multiple injuries of wrist and hand	0.305	0.694	0.000
T13 Other injuries of lower limb, level unspecified	0.305	0.694	0.000
T11 Other injuries of upper limb, level unspecified	0.305	0.694	0.000
T09 Other injuries of spine and trunk, level unspecified	0.305	0.694	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.305	0.694	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.305	0.694	0.000
T12 Fracture of lower limb, level unspecified	0.305	0.694	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.305	0.694	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.305	0.694	0.000
T10 Fracture of upper limb, level unspecified	0.305	0.694	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.305	0.694	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.305	0.694	0.000
T08 Fracture of spine, level unspecified	0.305	0.694	0.000
S62.7 Multiple fractures of fingers	0.305	0.695	0.000
S62.1 Fracture of other carpal bone(s)	0.305	0.695	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.695	0.305
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.695	0.305
K63.5 Polyp of colon	0.000	0.696	0.304
S62.3 Fracture of other metacarpal bone	0.304	0.696	0.000
K35-K38 Diseases of appendix	0.000	0.696	0.304
T38.9 Other and unspecified hormone antagonists	0.302	0.697	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.302	0.697	0.000
T38.7 Androgens and anabolic congeners	0.302	0.697	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.302	0.697	0.000
T38.5 Other oestrogens and progestogens	0.302	0.697	0.000
T38.4 Oral contraceptives	0.302	0.697	0.000
T38.2 Antithyroid drugs	0.302	0.697	0.000
T38.1 Thyroid hormones and substitutes	0.302	0.697	0.000
T38.0 Glucocorticoids and synthetic analogues	0.302	0.697	0.000
S52.71 Multiple fractures of forearm (open)	0.300	0.699	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.300	0.700	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.299	0.700	0.000
S02.51 Fracture of tooth (open)	0.299	0.701	0.000
K63.0 Abscess of intestine	0.000	0.701	0.299
T92.8 Sequelae of other specified injuries of upper limb	0.299	0.701	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.299	0.701	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.299	0.701	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.299	0.701	0.000
T92.0 Sequelae of open wound of upper limb	0.299	0.701	0.000
S42.31 Fracture of shaft of humerus (open)	0.298	0.702	0.000
T14 Injury of unspecified body region	0.298	0.702	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.297	0.703	0.000
S62.61 Fracture of other finger (open)	0.297	0.703	0.000
K63.2 Fistula of intestine	0.000	0.703	0.297
T93.8 Sequelae of other specified injuries of lower limb	0.296	0.704	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.296	0.704	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.296	0.704	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.296	0.704	0.000
T93.1 Sequelae of fracture of femur	0.296	0.704	0.000
T93.0 Sequelae of open wound of lower limb	0.296	0.704	0.000
K85.9 Acute pancreatitis, unspecified	0.000	0.704	0.296
S64.9 Injury of unspecified nerve at wrist and hand level	0.296	0.704	0.000
S64.8 Injury of other nerves at wrist and hand level	0.296	0.704	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.296	0.704	0.000
S64.1 Injury of median nerve at wrist and hand level	0.296	0.704	0.000
S56.2 Injury of other flexor muscle and tendon at forearm level	0.295	0.705	0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.295	0.705	0.000
S56.7 Injury of multiple muscles and tendons at forearm level	0.295	0.705	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.295	0.705	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.295	0.705	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.295	0.705	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.295	0.705	0.000
T50.8 Diagnostic agents	0.295	0.705	0.000
T50.7 Analeptics and opioid receptor antagonists	0.295	0.705	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.295	0.705	0.000
T50.5 Appetite depressants	0.295	0.705	0.000
T50.4 Drugs affecting uric acid metabolism	0.295	0.705	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.295	0.705	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.295	0.705	0.000
T50.1 Loop [high-ceiling] diuretics	0.295	0.705	0.000
T50.0 Mineralocorticoids and their antagonists	0.295	0.705	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.295	0.705	0.000
S60.2 Contusion of other parts of wrist and hand	0.295	0.705	0.000
S60.1 Contusion of finger(s) with damage to nail	0.295	0.705	0.000
S60.0 Contusion of finger(s) without damage to nail	0.295	0.705	0.000
S61.1 Open wound of finger(s) with damage to nail	0.294	0.706	0.000
K86.3 Pseudocyst of pancreas	0.000	0.706	0.294
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.293	0.707	0.000
S20 Superficial injury of thorax	0.292	0.708	0.000
S52.01 Fracture of upper end of ulna (open)	0.291	0.709	0.000
S02.21 Fracture of nasal bones (open)	0.290	0.709	0.000
T45.0 Antiallergic and antiemetic drugs	0.290	0.710	0.000
S09.7 Multiple injuries of head	0.290	0.710	0.000
S09.2 Traumatic rupture of ear drum	0.290	0.710	0.000
S09.1 Injury of muscle and tendon of head	0.290	0.710	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.290	0.710	0.000
S72 Fracture of femur	0.290	0.710	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.289	0.711	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.288	0.712	0.000
S32.3 Fracture of ilium	0.288	0.712	0.000
S32.2 Fracture of coccyx	0.288	0.712	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.287	0.713	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.287	0.713	0.000
S41.1 Open wound of upper arm	0.287	0.713	0.000
S41.0 Open wound of shoulder	0.287	0.713	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations