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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17229494
log Bayes Factor = 5.20366
Chromosome 21   position 38,928,100  (GRCh37) Explore rs17229494 on Ensembl!
Variant rs17229494 is part of Cluster X0079

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
I69 Sequelae of cerebrovascular disease
0.999 0.001 0.000
I63 Cerebral infarction
0.998 0.002 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.994 0.006 0.000
Chapter II Neoplasms
0.989 0.011 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.984 0.016 0.000
C43 Malignant melanoma of skin
0.984 0.016 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.983 0.017 0.000
I63.9 Cerebral infarction, unspecified
0.983 0.017 0.000
C34 Malignant neoplasm of bronchus and lung
0.977 0.023 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.976 0.024 0.000
C43.5 Malignant melanoma of trunk
0.973 0.027 0.000
I61 Intracerebral haemorrhage
0.966 0.034 0.000
C34.9 Bronchus or lung, unspecified
0.964 0.036 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.963 0.037 0.000
D00-D09 In situ neoplasms
0.954 0.046 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.935 0.065 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.930 0.070 0.000
I69.3 Sequelae of cerebral infarction
0.928 0.072 0.000
Chapter IX Diseases of the circulatory system
0.913 0.087 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.912 0.088 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.903 0.097 0.000
I71 Aortic aneurysm and dissection
0.902 0.098 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.901 0.099 0.000
# Top node
0.899 0.101 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.895 0.105 0.000
D04 Carcinoma in situ of skin
0.893 0.107 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.890 0.110 0.000
Chapter VI Diseases of the nervous system
0.884 0.116 0.000
I67 Other cerebrovascular diseases
0.883 0.117 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.879 0.121 0.000
Chapter VIII Diseases of the ear and mastoid process
0.879 0.121 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.867 0.133 0.000
D06 Carcinoma in situ of cervix uteri
0.865 0.135 0.000
C34.3 Lower lobe, bronchus or lung
0.864 0.136 0.000
I60 Subarachnoid haemorrhage
0.863 0.137 0.000
G81 Hemiplegia
0.859 0.141 0.000
C78.2 Secondary malignant neoplasm of pleura
0.856 0.144 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.850 0.150 0.000
C79 Secondary malignant neoplasm of other sites
0.849 0.151 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.848 0.152 0.000
C85.1 B-cell lymphoma, unspecified
0.845 0.155 0.000
G81.9 Hemiplegia, unspecified
0.844 0.156 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.843 0.157 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.841 0.159 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.834 0.166 0.000
C45 Mesothelioma
0.832 0.168 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.832 0.168 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.830 0.170 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.829 0.171 0.000
H60-H62 Diseases of external ear
0.829 0.171 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.825 0.175 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.822 0.178 0.000
D05 Carcinoma in situ of breast
0.822 0.178 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.821 0.179 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.817 0.183 0.000
G83 Other paralytic syndromes
0.811 0.189 0.000
Q60-Q64 Congenital malformations of the urinary system
0.810 0.190 0.000
H65-H75 Diseases of middle ear and mastoid
0.807 0.193 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.805 0.195 0.000
G70-G73 Diseases of myoneural junction and muscle
0.805 0.195 0.000
D06.9 Cervix, unspecified
0.802 0.198 0.000
C34.2 Middle lobe, bronchus or lung
0.799 0.201 0.000
H60 Otitis externa
0.798 0.202 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.798 0.202 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.795 0.205 0.000
C78.0 Secondary malignant neoplasm of lung
0.793 0.207 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.782 0.218 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.776 0.224 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.772 0.228 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.772 0.228 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.771 0.229 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.767 0.233 0.000
I67.1 Cerebral aneurysm, nonruptured
0.765 0.235 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.764 0.236 0.000
C49.2 Connective and soft tissue of lower limb, including hip
0.763 0.236 0.000
I63.8 Other cerebral infarction
0.760 0.240 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.760 0.240 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.759 0.241 0.000
G70 Myasthenia gravis and other myoneural disorders
0.759 0.241 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.756 0.244 0.000
I62 Other nontraumatic intracranial haemorrhage
0.755 0.245 0.000
I67.9 Cerebrovascular disease, unspecified
0.755 0.245 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.750 0.250 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.750 0.250 0.000
D04.5 Skin of trunk
0.747 0.253 0.000
I74 Arterial embolism and thrombosis
0.746 0.254 0.000
G83.4 Cauda equina syndrome
0.742 0.258 0.000
D04.9 Skin, unspecified
0.741 0.259 0.000
C45.9 Mesothelioma, unspecified
0.741 0.259 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.741 0.259 0.000
Chapter XXII Codes for special purposes
0.740 0.260 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.739 0.261 0.000
C81 Hodgkin's disease
0.737 0.263 0.000
C77.5 Intrapelvic lymph nodes
0.735 0.265 0.000
C79.2 Secondary malignant neoplasm of skin
0.732 0.268 0.000
I71.0 Dissection of aorta [any part]
0.731 0.269 0.000
I65.2 Occlusion and stenosis of carotid artery
0.731 0.269 0.000
D04.4 Skin of scalp and neck
0.728 0.272 0.000
G70.0 Myasthenia gravis
0.726 0.274 0.000
D05.0 Lobular carcinoma in situ
0.725 0.275 0.000
C32 Malignant neoplasm of larynx
0.723 0.277 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.723 0.277 0.000
D04.6 Skin of upper limb, including shoulder
0.719 0.281 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.719 0.281 0.000
H60.9 Otitis externa, unspecified
0.718 0.282 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.717 0.282 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.717 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.717 0.283 0.000
C77.1 Intrathoracic lymph nodes
0.717 0.283 0.000
D05.1 Intraductal carcinoma in situ
0.716 0.284 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.716 0.284 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.716 0.284 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.715 0.284 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.715 0.285 0.000
Q63 Other congenital malformations of kidney
0.714 0.286 0.000
H74 Other disorders of middle ear and mastoid
0.710 0.290 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.709 0.291 0.000
C43.9 Malignant melanoma of skin, unspecified
0.709 0.291 0.000
C34.1 Upper lobe, bronchus or lung
0.707 0.293 0.000
G35 Multiple sclerosis
0.707 0.293 0.000
C43.8 Overlapping malignant melanoma of skin
0.705 0.294 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.705 0.294 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.705 0.294 0.000
C43.0 Malignant melanoma of lip
0.705 0.294 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.705 0.295 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.705 0.295 0.000
C31 Malignant neoplasm of accessory sinuses
0.705 0.295 0.000
C37 Malignant neoplasm of thymus
0.705 0.295 0.000
C33 Malignant neoplasm of trachea
0.705 0.295 0.000
G80 Infantile cerebral palsy
0.701 0.299 0.000
C34.8 Overlapping lesion of bronchus and lung
0.701 0.299 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.700 0.299 0.000
H90-H95 Other disorders of ear
0.700 0.300 0.000
D04.3 Skin of other and unspecified parts of face
0.698 0.302 0.000
C43.4 Malignant melanoma of scalp and neck
0.698 0.302 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.697 0.303 0.000
D04.1 Skin of eyelid, including canthus
0.697 0.303 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.695 0.305 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.694 0.306 0.000
Q61 Cystic kidney disease
0.693 0.307 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.692 0.307 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.692 0.307 0.000
I72 Other aneurysm
0.692 0.308 0.000
Q18 Other congenital malformations of face and neck
0.690 0.310 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.689 0.311 0.000
C77.9 Lymph node, unspecified
0.688 0.312 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.688 0.312 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.684 0.316 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.681 0.319 0.000
I70 Atherosclerosis
0.680 0.320 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.680 0.320 0.000
I61.8 Other intracerebral haemorrhage
0.679 0.321 0.000
H60.8 Other otitis externa
0.679 0.321 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.676 0.324 0.000
Q80-Q89 Other congenital malformations
0.676 0.324 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.673 0.326 0.000
G83.8 Other specified paralytic syndromes
0.673 0.327 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.671 0.329 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.668 0.332 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.667 0.333 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.667 0.333 0.000
C46 Kaposi's sarcoma
0.667 0.333 0.000
C71 Malignant neoplasm of brain
0.666 0.333 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.666 0.334 0.000
C95 Leukaemia of unspecified cell type
0.665 0.334 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.665 0.335 0.000
I05-I09 Chronic rheumatic heart diseases
0.664 0.336 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.663 0.337 0.000
C77.8 Lymph nodes of multiple regions
0.659 0.341 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.659 0.341 0.000
I00-I02 Acute rheumatic fever
0.654 0.346 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.654 0.346 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.654 0.346 0.000
C94 Other leukaemias of specified cell type
0.654 0.346 0.000
C93 Monocytic leukaemia
0.654 0.346 0.000
C86 Other specified types of T/NK-cell lymphoma
0.654 0.346 0.000
S70-S79 Injuries to the hip and thigh
0.651 0.349 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.647 0.353 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.647 0.353 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.647 0.353 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.647 0.353 0.000
C49.3 Connective and soft tissue of thorax
0.645 0.355 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.645 0.355 0.000
G90-G99 Other disorders of the nervous system
0.645 0.355 0.000
I67.2 Cerebral atherosclerosis
0.644 0.356 0.000
H65 Nonsuppurative otitis media
0.644 0.356 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.640 0.360 0.000
Q64 Other congenital malformations of urinary system
0.640 0.360 0.000
C45.0 Mesothelioma of pleura
0.640 0.360 0.000
D04.8 Skin of other sites
0.640 0.360 0.000
D04.2 Skin of ear and external auricular canal
0.640 0.360 0.000
D04.0 Skin of lip
0.640 0.360 0.000
I74.5 Embolism and thrombosis of iliac artery
0.640 0.360 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.638 0.362 0.000
C85.0 Lymphosarcoma
0.638 0.362 0.000
H70 Mastoiditis and related conditions
0.638 0.362 0.000
C49.0 Connective and soft tissue of head, face and neck
0.638 0.362 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.637 0.363 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.634 0.366 0.000
C49.5 Connective and soft tissue of pelvis
0.634 0.366 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.633 0.367 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.633 0.367 0.000
I67.5 Moyamoya disease
0.633 0.367 0.000
I67.4 Hypertensive encephalopathy
0.633 0.367 0.000
I67.3 Progressive vascular leukoencephalopathy
0.633 0.367 0.000
S40-S49 Injuries to the shoulder and upper arm
0.632 0.368 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.632 0.368 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.630 0.370 0.000
G81.1 Spastic hemiplegia
0.628 0.372 0.000
H60.3 Other infective otitis externa
0.628 0.372 0.000
C34.0 Main bronchus
0.627 0.373 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.626 0.374 0.000
C49.9 Connective and soft tissue, unspecified
0.624 0.376 0.000
C80 Malignant neoplasm without specification of site
0.624 0.376 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.622 0.378 0.000
Q35-Q37 Cleft lip and cleft palate
0.622 0.378 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.622 0.378 0.000
T92 Sequelae of injuries of upper limb
0.622 0.378 0.000
I10-I15 Hypertensive diseases
0.622 0.378 0.000
M65-M68 Disorders of synovium and tendon
0.622 0.378 0.000
H66 Suppurative and unspecified otitis media
0.621 0.379 0.000
D06.7 Other parts of cervix
0.620 0.379 0.000
D06.1 Exocervix
0.620 0.379 0.000
D06.0 Endocervix
0.620 0.379 0.000
C82.3 Follicular lymphoma grade IIIa
0.620 0.380 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.619 0.381 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.619 0.381 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.619 0.381 0.000
C77.2 Intra-abdominal lymph nodes
0.618 0.382 0.000
G82 Paraplegia and tetraplegia
0.616 0.384 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.616 0.384 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.616 0.384 0.000
G81.0 Flaccid hemiplegia
0.616 0.384 0.000
H60.4 Cholesteatoma of external ear
0.615 0.385 0.000
C92 Myeloid leukaemia
0.614 0.386 0.000
C30.0 Nasal cavity
0.612 0.387 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.611 0.388 0.000
H72 Perforation of tympanic membrane
0.611 0.389 0.000
C45.7 Mesothelioma of other sites
0.610 0.390 0.000
I60.8 Other subarachnoid haemorrhage
0.609 0.390 0.000
C49.8 Overlapping lesion of connective and soft tissue
0.608 0.392 0.000
C49.6 Connective and soft tissue of trunk, unspecified
0.608 0.392 0.000
C49.4 Connective and soft tissue of abdomen
0.608 0.392 0.000
H60.1 Cellulitis of external ear
0.607 0.392 0.000
M40-M43 Deforming dorsopathies
0.606 0.394 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.605 0.395 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.605 0.395 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.605 0.395 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.605 0.395 0.000
I65.1 Occlusion and stenosis of basilar artery
0.605 0.395 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.605 0.395 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.603 0.397 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.603 0.397 0.000
Q00-Q07 Congenital malformations of the nervous system
0.600 0.400 0.000
C81.9 Hodgkin's disease, unspecified
0.600 0.400 0.000
D09 Carcinoma in situ of other and unspecified sites
0.599 0.400 0.000
Q63.1 Lobulated, fused and horseshoe kidney
0.598 0.402 0.000
I05 Rheumatic mitral valve diseases
0.598 0.402 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.597 0.403 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.597 0.403 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.597 0.403 0.000
C45.2 Mesothelioma of pericardium
0.597 0.403 0.000
C45.1 Mesothelioma of peritoneum
0.597 0.403 0.000
H73 Other disorders of tympanic membrane
0.596 0.404 0.000
C82.2 Large cell, follicular
0.594 0.406 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.594 0.406 0.000
Q63.0 Accessory kidney
0.594 0.406 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.593 0.407 0.000
Q18.1 Preauricular sinus and cyst
0.593 0.407 0.000
S70 Superficial injury of hip and thigh
0.592 0.408 0.000
C88 Malignant immunoproliferative diseases
0.590 0.410 0.000
H92 Otalgia and effusion of ear
0.590 0.410 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.590 0.410 0.000
D05.7 Other carcinoma in situ of breast
0.589 0.411 0.000
C76.3 Pelvis
0.588 0.412 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.587 0.413 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.586 0.414 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.585 0.415 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.584 0.416 0.000
M67 Other disorders of synovium and tendon
0.584 0.416 0.000
Q12 Congenital lens malformations
0.584 0.416 0.000
C77.0 Lymph nodes of head, face and neck
0.583 0.417 0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.582 0.417 0.000
M86-M90 Other osteopathies
0.582 0.418 0.000
G83.9 Paralytic syndrome, unspecified
0.582 0.418 0.000
G83.5 Locked-in syndrome
0.582 0.418 0.000
G83.3 Monoplegia, unspecified
0.582 0.418 0.000
G83.0 Diplegia of upper limbs
0.582 0.418 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.582 0.418 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.581 0.419 0.000
H69 Other disorders of Eustachian tube
0.581 0.419 0.000
C49.1 Connective and soft tissue of upper limb, including shoulder
0.580 0.420 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.579 0.421 0.000
H68 Eustachian salpingitis and obstruction
0.579 0.421 0.000
H67 Otitis media in diseases classified elsewhere
0.579 0.421 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.577 0.422 0.000
I12 Hypertensive renal disease
0.577 0.423 0.000
C32.0 Glottis
0.576 0.423 0.000
S79 Other and unspecified injuries of hip and thigh
0.576 0.424 0.000
G83.1 Monoplegia of lower limb
0.575 0.424 0.000
U51 Admission status on psychiatric patients
0.575 0.424 0.000
G72 Other myopathies
0.575 0.424 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.575 0.425 0.000
M60-M63 Disorders of muscles
0.575 0.425 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.575 0.425 0.000
G80.9 Infantile cerebral palsy, unspecified
0.573 0.427 0.000
Q18.0 Sinus, fistula and cyst of branchial cleft
0.573 0.427 0.000
H60.5 Acute otitis externa, non-infective
0.572 0.428 0.000
H60.2 Malignant otitis externa
0.572 0.428 0.000
H60.0 Abscess of external ear
0.572 0.428 0.000
S10-S19 Injuries to the neck
0.572 0.428 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.572 0.428 0.000
C70 Malignant neoplasm of meninges
0.572 0.428 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.571 0.429 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.571 0.429 0.000
C50-C50 Malignant neoplasm of breast
0.570 0.430 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.570 0.430 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.567 0.432 0.000
G12 Spinal muscular atrophy and related syndromes
0.567 0.433 0.000
S40 Superficial injury of shoulder and upper arm
0.565 0.435 0.000
Q61.5 Medullary cystic kidney
0.565 0.435 0.000
C71.1 Frontal lobe
0.563 0.437 0.000
C32.1 Supraglottis
0.562 0.438 0.000
C69 Malignant neoplasm of eye and adnexa
0.562 0.438 0.000
Q61.9 Cystic kidney disease, unspecified
0.560 0.440 0.000
T23 Burn and corrosion of wrist and hand
0.558 0.442 0.000
G36 Other acute disseminated demyelination
0.557 0.443 0.000
Q50-Q56 Congenital malformations of genital organs
0.556 0.444 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.554 0.446 0.000
G83.2 Monoplegia of upper limb
0.554 0.446 0.000
C82.6 Cutaneous follicle centre lymphoma
0.554 0.446 0.000
C82.5 Diffuse follicle centre lymphoma
0.554 0.446 0.000
C82.4 Follicular lymphoma grade IIIb
0.554 0.446 0.000
C82.0 Small cleaved cell, follicular
0.554 0.446 0.000
Q17 Other congenital malformations of ear
0.553 0.447 0.000
Q16 Congenital malformations of ear causing impairment of hearing
0.553 0.447 0.000
Q15 Other congenital malformations of eye
0.553 0.447 0.000
Q14 Congenital malformations of posterior segment of eye
0.553 0.447 0.000
Q13 Congenital malformations of anterior segment of eye
0.553 0.447 0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos
0.553 0.447 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.553 0.447 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.552 0.448 0.000
H61 Other disorders of external ear
0.552 0.448 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.552 0.448 0.000
Q61.3 Polycystic kidney, unspecified
0.551 0.449 0.000
C30.1 Middle ear
0.550 0.450 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.550 0.450 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.549 0.451 0.000
H74.0 Tympanosclerosis
0.548 0.451 0.000
C81.1 Nodular sclerosis
0.547 0.453 0.000
T93 Sequelae of injuries of lower limb
0.546 0.454 0.000
G63.2 Diabetic polyneuropathy
0.545 0.455 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.545 0.455 0.000
G70.9 Myoneural disorder, unspecified
0.544 0.456 0.000
G70.8 Other specified myoneural disorders
0.544 0.456 0.000
G70.2 Congenital and developmental myasthenia
0.544 0.456 0.000
G70.1 Toxic myoneural disorders
0.544 0.456 0.000
Q82 Other congenital malformations of skin
0.544 0.456 0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.542 0.458 0.000
C77.4 Inguinal and lower limb lymph nodes
0.542 0.458 0.000
I62.1 Nontraumatic extradural haemorrhage
0.541 0.459 0.000
I72.4 Aneurysm of artery of lower extremity
0.541 0.459 0.000
T90 Sequelae of injuries of head
0.539 0.461 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.539 0.461 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.538 0.462 0.000
C76.8 Overlapping lesion of other and ill-defined sites
0.537 0.462 0.000
C76.7 Other ill-defined sites
0.537 0.462 0.000
C76.5 Lower limb
0.537 0.462 0.000
C76.4 Upper limb
0.537 0.462 0.000
C76.2 Abdomen
0.537 0.462 0.000
C76.1 Thorax
0.537 0.462 0.000
C76.0 Head, face and neck
0.537 0.462 0.000
I05.9 Mitral valve disease, unspecified
0.538 0.462 0.000
D03 Melanoma in situ
0.536 0.463 0.000
S70.1 Contusion of thigh
0.536 0.464 0.000
G91 Hydrocephalus
0.536 0.464 0.000
I09 Other rheumatic heart diseases
0.535 0.464 0.000
G37 Other demyelinating diseases of central nervous system
0.535 0.465 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.535 0.465 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.535 0.465 0.000
I12.0 Hypertensive renal disease with renal failure
0.535 0.465 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.535 0.465 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.535 0.465 0.000
U80 Agent resistant to penicillin and related antibiotics
0.535 0.465 0.000
C09 Malignant neoplasm of tonsil
0.534 0.466 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.533 0.467 0.000
G71 Primary disorders of muscles
0.533 0.467 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.530 0.470 0.000
G90 Disorders of autonomic nervous system
0.530 0.470 0.000
G82.5 Tetraplegia, unspecified
0.529 0.470 0.000
M67.1 Other contracture of tendon (sheath)
0.530 0.470 0.000
M50-M54 Other dorsopathies
0.529 0.471 0.000
I72.0 Aneurysm of carotid artery
0.529 0.471 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.528 0.471 0.000
C81.7 Other Hodgkin's disease
0.528 0.471 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.528 0.471 0.000
C81.3 Lymphocytic depletion
0.528 0.471 0.000
C81.2 Mixed cellularity
0.528 0.471 0.000
C81.0 Lymphocytic predominance
0.528 0.471 0.000
H70.8 Other mastoiditis and related conditions
0.528 0.472 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.528 0.472 0.000
I70.1 Atherosclerosis of renal artery
0.528 0.472 0.000
Q24 Other congenital malformations of heart
0.527 0.473 0.000
G30-G32 Other degenerative diseases of the nervous system
0.527 0.473 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.526 0.474 0.000
C71.8 Overlapping lesion of brain
0.526 0.474 0.000
H80-H83 Diseases of inner ear
0.526 0.474 0.000
Q23 Congenital malformations of aortic and mitral valves
0.525 0.475 0.000
H92.1 Otorrhoea
0.525 0.475 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.524 0.476 0.000
H74.4 Polyp of middle ear
0.524 0.476 0.000
T00-T07 Injuries involving multiple body regions
0.523 0.477 0.000
S79.9 Unspecified injury of hip and thigh
0.523 0.477 0.000
G61 Inflammatory polyneuropathy
0.523 0.477 0.000
M86 Osteomyelitis
0.523 0.477 0.000
H66.0 Acute suppurative otitis media
0.521 0.479 0.000
C51-C58 Malignant neoplasms of female genital organs
0.521 0.479 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.521 0.479 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.520 0.480 0.000
D02.0 Larynx
0.519 0.481 0.000
C32.8 Overlapping lesion of larynx
0.519 0.481 0.000
C32.3 Laryngeal cartilage
0.519 0.481 0.000
C32.2 Subglottis
0.519 0.481 0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck
0.519 0.481 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.518 0.482 0.000
M43 Other deforming dorsopathies
0.518 0.482 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.518 0.482 0.000
C64-C68 Malignant neoplasms of urinary tract
0.517 0.483 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.517 0.483 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.516 0.484 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.516 0.484 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.515 0.485 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.514 0.486 0.000
I66.8 Occlusion and stenosis of other cerebral artery
0.514 0.486 0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.514 0.486 0.000
I66.3 Occlusion and stenosis of cerebellar arteries
0.514 0.486 0.000
I66.2 Occlusion and stenosis of posterior cerebral artery
0.514 0.486 0.000
I66.1 Occlusion and stenosis of anterior cerebral artery
0.514 0.486 0.000
I66.0 Occlusion and stenosis of middle cerebral artery
0.514 0.486 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.514 0.486 0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.514 0.486 0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.514 0.486 0.000
I68.0 Cerebral amyloid angiopathy
0.514 0.486 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.514 0.486 0.000
U51.1 Previously admitted to a psychiatric hospital of the provider
0.513 0.487 0.000
G64 Other disorders of peripheral nervous system
0.512 0.487 0.000
Q63.9 Congenital malformation of kidney, unspecified
0.512 0.488 0.000
Q63.8 Other specified congenital malformations of kidney
0.512 0.488 0.000
Q63.3 Hyperplastic and giant kidney
0.512 0.488 0.000
Q63.2 Ectopic kidney
0.512 0.488 0.000
M62 Other disorders of muscle
0.511 0.489 0.000
G96 Other disorders of central nervous system
0.510 0.490 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.510 0.490 0.000
T87 Complications peculiar to reattachment and amputation
0.510 0.490 0.000
M41 Scoliosis
0.509 0.491 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.509 0.491 0.000
H74.1 Adhesive middle ear disease
0.509 0.491 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.508 0.492 0.000
I79.1 Aortitis in diseases classified elsewhere
0.508 0.492 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.508 0.492 0.000
Q28 Other congenital malformations of circulatory system
0.508 0.492 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.507 0.493 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.505 0.494 0.000
C31.9 Accessory sinus, unspecified
0.505 0.495 0.000
C31.8 Overlapping lesion of accessory sinuses
0.505 0.495 0.000
C31.3 Sphenoidal sinus
0.505 0.495 0.000
C31.2 Frontal sinus
0.505 0.495 0.000
C31.1 Ethmoidal sinus
0.505 0.495 0.000
C31.0 Maxillary sinus
0.505 0.495 0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura
0.505 0.495 0.000
C38.4 Pleura
0.505 0.495 0.000
C38.3 Mediastinum, part unspecified
0.505 0.495 0.000
C38.2 Posterior mediastinum
0.505 0.495 0.000
C38.1 Anterior mediastinum
0.505 0.495 0.000
C38.0 Heart
0.505 0.495 0.000
C39.9 Ill-defined sites within the respiratory system
0.505 0.495 0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs
0.505 0.495 0.000
C39.0 Upper respiratory tract, part unspecified
0.505 0.495 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.504 0.496 0.000
G80.8 Other infantile cerebral palsy
0.502 0.497 0.000
G80.4 Ataxic cerebral palsy
0.502 0.497 0.000
G80.3 Dyskinetic cerebral palsy
0.502 0.497 0.000
G80.2 Infantile hemiplegia
0.502 0.497 0.000
G80.1 Spastic diplegia
0.502 0.497 0.000
G80.0 Spastic cerebral palsy
0.502 0.497 0.000
D02.4 Respiratory system, unspecified
0.502 0.498 0.000
D02.3 Other parts of respiratory system
0.502 0.498 0.000
D02.2 Bronchus and lung
0.502 0.498 0.000
D02.1 Trachea
0.502 0.498 0.000
C78.7 Secondary malignant neoplasm of liver
0.502 0.498 0.000
M89 Other disorders of bone
0.502 0.498 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.502 0.498 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.501 0.499 0.000
C12 Malignant neoplasm of pyriform sinus
0.500 0.500 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.500 0.500 0.000
G14 Postpolio syndrome
0.500 0.500 0.000
G10 Huntington's disease
0.500 0.500 0.000
C01 Malignant neoplasm of base of tongue
0.500 0.500 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.499 0.501 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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