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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17231595
log Bayes Factor = 11.4264
Chromosome 10   position 68,724,763  (GRCh37) Explore rs17231595 on Ensembl!
Variant rs17231595 is part of Cluster X0018

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
I60-I69 Cerebrovascular diseases
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.994 0.006 0.000
S60-S69 Injuries to the wrist and hand
0.989 0.011 0.000
S00-S09 Injuries to the head
0.971 0.029 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.970 0.030 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.968 0.032 0.000
M05-M14 Inflammatory polyarthropathies
0.964 0.036 0.000
I69 Sequelae of cerebrovascular disease
0.963 0.037 0.000
G90-G99 Other disorders of the nervous system
0.961 0.039 0.000
M06 Other rheumatoid arthritis
0.960 0.040 0.000
M06.9 Rheumatoid arthritis, unspecified
0.956 0.044 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.953 0.047 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.949 0.051 0.000
F60-F69 Disorders of adult personality and behaviour
0.943 0.057 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.941 0.059 0.000
S40-S49 Injuries to the shoulder and upper arm
0.938 0.062 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.936 0.064 0.000
I50 Heart failure
0.934 0.066 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.932 0.068 0.000
G40-G47 Episodic and paroxysmal disorders
0.929 0.071 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.923 0.077 0.000
I42 Cardiomyopathy
0.923 0.077 0.000
I44 Atrioventricular and left bundle-branch block
0.918 0.082 0.000
S09 Other and unspecified injuries of head
0.912 0.088 0.000
G40 Epilepsy
0.911 0.089 0.000
O60-O75 Complications of labour and delivery
0.911 0.089 0.000
F60 Specific personality disorders
0.903 0.097 0.000
Chapter X Diseases of the respiratory system
0.903 0.097 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.901 0.099 0.000
F41 Other anxiety disorders
0.898 0.102 0.000
S06 Intracranial injury
0.895 0.105 0.000
I51 Complications and ill-defined descriptions of heart disease
0.895 0.105 0.000
G40.9 Epilepsy, unspecified
0.895 0.105 0.000
Chapter XXII Codes for special purposes
0.891 0.109 0.000
G95 Other diseases of spinal cord
0.889 0.111 0.000
I49 Other cardiac arrhythmias
0.889 0.111 0.000
G93 Other disorders of brain
0.887 0.113 0.000
S20-S29 Injuries to the thorax
0.885 0.115 0.000
I42.0 Dilated cardiomyopathy
0.883 0.117 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.882 0.118 0.000
S60 Superficial injury of wrist and hand
0.880 0.120 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.879 0.121 0.000
I67 Other cerebrovascular diseases
0.878 0.122 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.878 0.122 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.877 0.123 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.871 0.129 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.870 0.130 0.000
S09.9 Unspecified injury of head
0.869 0.131 0.000
M91-M94 Chondropathies
0.868 0.132 0.000
S42 Fracture of shoulder and upper arm
0.865 0.135 0.000
I50.1 Left ventricular failure
0.864 0.136 0.000
S62 Fracture at wrist and hand level
0.864 0.136 0.000
I69.3 Sequelae of cerebral infarction
0.861 0.139 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.852 0.148 0.000
G81 Hemiplegia
0.850 0.150 0.000
I47 Paroxysmal tachycardia
0.849 0.151 0.000
I60 Subarachnoid haemorrhage
0.841 0.159 0.000
T39.1 4-Aminophenol derivatives
0.837 0.163 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.836 0.164 0.000
E00-E07 Disorders of thyroid gland
0.834 0.166 0.000
F60.9 Personality disorder, unspecified
0.834 0.166 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.833 0.167 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.833 0.167 0.000
F43 Reaction to severe stress, and adjustment disorders
0.832 0.168 0.000
F20 Schizophrenia
0.832 0.168 0.000
S64 Injury of nerves at wrist and hand level
0.831 0.169 0.000
G30-G32 Other degenerative diseases of the nervous system
0.828 0.172 0.000
I67.2 Cerebral atherosclerosis
0.828 0.172 0.000
Chapter VII Diseases of the eye and adnexa
0.828 0.172 0.000
M86-M90 Other osteopathies
0.827 0.173 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.826 0.174 0.000
I46 Cardiac arrest
0.823 0.177 0.000
S00 Superficial injury of head
0.823 0.177 0.000
F10.0 Acute intoxication
0.818 0.182 0.000
I62 Other nontraumatic intracranial haemorrhage
0.815 0.185 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.812 0.188 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.811 0.189 0.000
F41.9 Anxiety disorder, unspecified
0.809 0.191 0.000
I44.1 Atrioventricular block, second degree
0.806 0.194 0.000
G70-G73 Diseases of myoneural junction and muscle
0.804 0.196 0.000
F10.1 Harmful use
0.804 0.196 0.000
I63 Cerebral infarction
0.803 0.197 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.800 0.200 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.800 0.200 0.000
S90-S99 Injuries to the ankle and foot
0.799 0.201 0.000
S80-S89 Injuries to the knee and lower leg
0.798 0.202 0.000
I49.5 Sick sinus syndrome
0.798 0.202 0.000
F60.3 Emotionally unstable personality disorder
0.798 0.202 0.000
F40 Phobic anxiety disorders
0.797 0.203 0.000
Chapter XX External causes of morbidity and mortality
0.793 0.207 0.000
M11 Other crystal arthropathies
0.793 0.207 0.000
I65.2 Occlusion and stenosis of carotid artery
0.792 0.208 0.000
G82 Paraplegia and tetraplegia
0.792 0.208 0.000
S61 Open wound of wrist and hand
0.789 0.211 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.788 0.211 0.000
T79-T79 Certain early complications of trauma
0.788 0.211 0.000
O62 Abnormalities of forces of labour
0.788 0.212 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.786 0.214 0.000
E04 Other non-toxic goitre
0.786 0.214 0.000
G81.9 Hemiplegia, unspecified
0.784 0.216 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.783 0.217 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.783 0.217 0.000
S69 Other and unspecified injuries of wrist and hand
0.781 0.219 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.781 0.219 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.780 0.219 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.775 0.225 0.000
O70 Perineal laceration during delivery
0.775 0.225 0.000
I86 Varicose veins of other sites
0.772 0.228 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.772 0.228 0.000
I47.2 Ventricular tachycardia
0.771 0.229 0.000
J20-J22 Other acute lower respiratory infections
0.769 0.231 0.000
S20 Superficial injury of thorax
0.769 0.231 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.768 0.231 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.768 0.232 0.000
G95.9 Disease of spinal cord, unspecified
0.767 0.233 0.000
S70-S79 Injuries to the hip and thigh
0.766 0.234 0.000
F29 Unspecified nonorganic psychosis
0.765 0.235 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.765 0.235 0.000
S42.2 Fracture of upper end of humerus
0.765 0.235 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.765 0.235 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.765 0.235 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.760 0.240 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.760 0.240 0.000
S06.2 Diffuse brain injury
0.759 0.241 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.759 0.241 0.000
I61 Intracerebral haemorrhage
0.758 0.242 0.000
T40.2 Other opioids
0.757 0.243 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.756 0.244 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.756 0.244 0.000
M06.3 Rheumatoid nodule
0.756 0.244 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.755 0.245 0.000
H53-H54 Visual disturbances and blindness
0.752 0.248 0.000
J09-J18 Influenza and pneumonia
0.752 0.248 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.751 0.249 0.000
H43-H45 Disorders of vitreous body and globe
0.750 0.250 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.749 0.251 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.748 0.252 0.000
I49.9 Cardiac arrhythmia, unspecified
0.746 0.254 0.000
M80-M85 Disorders of bone density and structure
0.745 0.254 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.745 0.255 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.745 0.255 0.000
I51.9 Heart disease, unspecified
0.744 0.256 0.000
S68 Traumatic amputation of wrist and hand
0.741 0.259 0.000
I44.7 Left bundle-branch block, unspecified
0.741 0.259 0.000
G93.3 Postviral fatigue syndrome
0.740 0.260 0.000
I84 Haemorrhoids
0.740 0.260 0.000
G83 Other paralytic syndromes
0.740 0.260 0.000
E20-E35 Disorders of other endocrine glands
0.739 0.261 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.738 0.262 0.000
M06.0 Seronegative rheumatoid arthritis
0.738 0.262 0.000
I51.4 Myocarditis, unspecified
0.737 0.263 0.000
F80-F89 Disorders of psychological development
0.737 0.263 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.736 0.264 0.000
M05 Seropositive rheumatoid arthritis
0.736 0.264 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.734 0.266 0.000
G93.6 Cerebral oedema
0.734 0.266 0.000
S40 Superficial injury of shoulder and upper arm
0.734 0.266 0.000
O85-O92 Complications predominantly related to the puerperium
0.734 0.266 0.000
S50-S59 Injuries to the elbow and forearm
0.734 0.266 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.733 0.267 0.000
O72 Postpartum haemorrhage
0.732 0.268 0.000
E04.1 Non-toxic single thyroid nodule
0.732 0.268 0.000
S60.8 Other superficial injuries of wrist and hand
0.731 0.269 0.000
I50.9 Heart failure, unspecified
0.731 0.269 0.000
G90 Disorders of autonomic nervous system
0.731 0.269 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.730 0.270 0.000
O70.0 First degree perineal laceration during delivery
0.730 0.270 0.000
S42.4 Fracture of lower end of humerus
0.728 0.272 0.000
F23 Acute and transient psychotic disorders
0.728 0.272 0.000
G44 Other headache syndromes
0.727 0.273 0.000
G95.8 Other specified diseases of spinal cord
0.727 0.273 0.000
I51.8 Other ill-defined heart diseases
0.727 0.273 0.000
G95.2 Cord compression, unspecified
0.726 0.274 0.000
M60-M63 Disorders of muscles
0.726 0.274 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.720 0.280 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.719 0.281 0.000
F10.2 Dependence syndrome
0.718 0.282 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M45-M49 Spondylopathies
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I33 Acute and subacute endocarditis
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
F20.0 Paranoid schizophrenia
0.715 0.285 0.000
T39.0 Salicylates
0.715 0.285 0.000
G93.9 Disorder of brain, unspecified
0.714 0.286 0.000
F43.2 Adjustment disorders
0.714 0.286 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.713 0.287 0.000
F10.3 Withdrawal state
0.713 0.287 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.713 0.287 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.713 0.287 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.713 0.287 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.713 0.287 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.713 0.287 0.000
T36 Poisoning by systemic antibiotics
0.713 0.287 0.000
U88 Agent resistant to multiple antibiotics
0.712 0.288 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.712 0.288 0.000
G20-G26 Extrapyramidal and movement disorders
0.710 0.290 0.000
F22 Persistent delusional disorders
0.710 0.290 0.000
S65 Injury of blood vessels at wrist and hand level
0.709 0.291 0.000
M93 Other osteochondropathies
0.709 0.291 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.709 0.291 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.708 0.292 0.000
I86.1 Scrotal varices
0.707 0.293 0.000
M94 Other disorders of cartilage
0.706 0.294 0.000
G35 Multiple sclerosis
0.705 0.295 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.705 0.295 0.000
F99-F99 Unspecified mental disorder
0.704 0.296 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.704 0.296 0.000
J95-J99 Other diseases of the respiratory system
0.704 0.296 0.000
I46.9 Cardiac arrest, unspecified
0.704 0.296 0.000
I50.0 Congestive heart failure
0.703 0.297 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.702 0.298 0.000
M07 Psoriatic and enteropathic arthropathies
0.701 0.299 0.000
I51.0 Cardiac septal defect, acquired
0.701 0.299 0.000
O62.2 Other uterine inertia
0.699 0.301 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.698 0.301 0.000
I44.2 Atrioventricular block, complete
0.698 0.302 0.000
I81 Portal vein thrombosis
0.698 0.302 0.000
M87 Osteonecrosis
0.698 0.302 0.000
M92 Other juvenile osteochondrosis
0.697 0.303 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.697 0.303 0.000
S08 Traumatic amputation of part of head
0.696 0.303 0.000
S07 Crushing injury of head
0.696 0.303 0.000
S05 Injury of eye and orbit
0.696 0.303 0.000
S04 Injury of cranial nerves
0.696 0.303 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.696 0.303 0.000
I38 Endocarditis, valve unspecified
0.696 0.304 0.000
S61.0 Open wound of finger(s) without damage to nail
0.696 0.304 0.000
M00-M03 Infectious arthropathies
0.695 0.305 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.694 0.306 0.000
F48 Other neurotic disorders
0.694 0.306 0.000
F44 Dissociative [conversion] disorders
0.694 0.306 0.000
F42 Obsessive-compulsive disorder
0.694 0.306 0.000
E50-E64 Other nutritional deficiencies
0.694 0.306 0.000
S42.20 Fracture of upper end of humerus (closed)
0.694 0.306 0.000
O71 Other obstetric trauma
0.693 0.307 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.693 0.307 0.000
S06.8 Other intracranial injuries
0.692 0.308 0.000
S06.3 Focal brain injury
0.692 0.308 0.000
M14 Arthropathies in other diseases classified elsewhere
0.691 0.309 0.000
M12 Other specific arthropathies
0.691 0.309 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.691 0.309 0.000
M08 Juvenile arthritis
0.691 0.309 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.690 0.309 0.000
O66 Other obstructed labour
0.690 0.310 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.689 0.311 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.689 0.311 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.689 0.311 0.000
G92 Toxic encephalopathy
0.689 0.311 0.000
M06.8 Other specified rheumatoid arthritis
0.689 0.311 0.000
M06.4 Inflammatory polyarthropathy
0.689 0.311 0.000
M06.2 Rheumatoid bursitis
0.689 0.311 0.000
M06.1 Adult-onset Still's disease
0.689 0.311 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.688 0.312 0.000
I42.2 Other hypertrophic cardiomyopathy
0.688 0.312 0.000
I30 Acute pericarditis
0.688 0.312 0.000
F45 Somatoform disorders
0.686 0.314 0.000
S64.3 Injury of digital nerve of thumb
0.686 0.314 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.686 0.314 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.686 0.314 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.685 0.315 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.683 0.317 0.000
T39.4 Antirheumatics, not elsewhere classified
0.683 0.317 0.000
T39.2 Pyrazolone derivatives
0.683 0.317 0.000
S00.1 Contusion of eyelid and periocular area
0.683 0.317 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.683 0.317 0.000
S00.8 Superficial injury of other parts of head
0.682 0.318 0.000
I44.6 Other and unspecified fascicular block
0.682 0.318 0.000
S42.0 Fracture of clavicle
0.682 0.318 0.000
E07 Other disorders of thyroid
0.681 0.319 0.000
F20.9 Schizophrenia, unspecified
0.680 0.320 0.000
T40.4 Other synthetic narcotics
0.680 0.320 0.000
G91 Hydrocephalus
0.679 0.321 0.000
I89.1 Lymphangitis
0.679 0.321 0.000
G41 Status epilepticus
0.677 0.323 0.000
F68 Other disorders of adult personality and behaviour
0.676 0.324 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.676 0.324 0.000
F65 Disorders of sexual preference
0.676 0.324 0.000
F64 Gender identity disorders
0.676 0.324 0.000
F63 Habit and impulse disorders
0.676 0.324 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.676 0.324 0.000
F69 Unspecified disorder of adult personality and behaviour
0.676 0.324 0.000
F61 Mixed and other personality disorders
0.676 0.324 0.000
O73 Retained placenta and membranes, without haemorrhage
0.676 0.324 0.000
G93.8 Other specified disorders of brain
0.676 0.324 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.676 0.324 0.000
S62.2 Fracture of first metacarpal bone
0.675 0.324 0.000
M86 Osteomyelitis
0.675 0.325 0.000
J90-J94 Other diseases of pleura
0.674 0.326 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.674 0.326 0.000
F40.2 Specific (isolated) phobias
0.674 0.326 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.673 0.327 0.000
I44.3 Other and unspecified atrioventricular block
0.673 0.327 0.000
S62.6 Fracture of other finger
0.673 0.327 0.000
J22 Unspecified acute lower respiratory infection
0.673 0.327 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.673 0.327 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.672 0.327 0.000
S48 Traumatic amputation of shoulder and upper arm
0.672 0.327 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.672 0.327 0.000
S44 Injury of nerves at shoulder and upper arm level
0.672 0.327 0.000
S41 Open wound of shoulder and upper arm
0.672 0.327 0.000
S47 Crushing injury of shoulder and upper arm
0.672 0.327 0.000
F25 Schizoaffective disorders
0.671 0.329 0.000
F28 Other nonorganic psychotic disorders
0.671 0.329 0.000
F24 Induced delusional disorder
0.671 0.329 0.000
F21 Schizotypal disorder
0.671 0.329 0.000
M11.2 Other chondrocalcinosis
0.671 0.329 0.000
H54 Blindness and low vision
0.669 0.331 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.669 0.331 0.000
I31 Other diseases of pericardium
0.667 0.333 0.000
G93.4 Encephalopathy, unspecified
0.667 0.333 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.666 0.334 0.000
F10.4 Withdrawal state with delirium
0.666 0.334 0.000
T42.4 Benzodiazepines
0.663 0.336 0.000
S62.3 Fracture of other metacarpal bone
0.663 0.337 0.000
M10 Gout
0.663 0.337 0.000
G82.5 Tetraplegia, unspecified
0.662 0.338 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.662 0.338 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.662 0.338 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.662 0.338 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.662 0.338 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.662 0.338 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.662 0.338 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.662 0.338 0.000
F11 Mental and behavioural disorders due to use of opioids
0.662 0.338 0.000
I42.8 Other cardiomyopathies
0.662 0.338 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.662 0.338 0.000
I42.6 Alcoholic cardiomyopathy
0.662 0.338 0.000
I42.5 Other restrictive cardiomyopathy
0.662 0.338 0.000
I42.4 Endocardial fibroelastosis
0.662 0.338 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.662 0.338 0.000
G80 Infantile cerebral palsy
0.661 0.339 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.661 0.339 0.000
E04.2 Non-toxic multinodular goitre
0.661 0.339 0.000
T66-T78 Other and unspecified effects of external causes
0.661 0.339 0.000
J60-J70 Lung diseases due to external agents
0.660 0.340 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.659 0.341 0.000
I44.5 Left posterior fascicular block
0.658 0.342 0.000
I44.4 Left anterior fascicular block
0.658 0.342 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.657 0.343 0.000
I84.2 Internal haemorrhoids without complication
0.656 0.344 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.654 0.345 0.000
S67 Crushing injury of wrist and hand
0.654 0.346 0.000
S09.8 Other specified injuries of head
0.654 0.346 0.000
S09.7 Multiple injuries of head
0.654 0.346 0.000
S09.2 Traumatic rupture of ear drum
0.654 0.346 0.000
S09.1 Injury of muscle and tendon of head
0.654 0.346 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.654 0.346 0.000
G40.8 Other epilepsy
0.653 0.347 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.653 0.347 0.000
G40.5 Special epileptic syndromes
0.653 0.347 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.653 0.347 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.653 0.347 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.653 0.347 0.000
O74 Complications of anaesthesia during labour and delivery
0.653 0.347 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.653 0.347 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.653 0.347 0.000
O61 Failed induction of labour
0.653 0.347 0.000
O60 Preterm delivery
0.653 0.347 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.653 0.347 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.651 0.349 0.000
I45 Other conduction disorders
0.651 0.349 0.000
X60-X84 Intentional self-harm
0.650 0.350 0.000
M40-M43 Deforming dorsopathies
0.648 0.352 0.000
F60.8 Other specific personality disorders
0.648 0.352 0.000
F60.7 Dependent personality disorder
0.648 0.352 0.000
F60.6 Anxious [avoidant] personality disorder
0.648 0.352 0.000
F60.5 Anankastic personality disorder
0.648 0.352 0.000
F60.4 Histrionic personality disorder
0.648 0.352 0.000
F60.2 Dissocial personality disorder
0.648 0.352 0.000
F60.1 Schizoid personality disorder
0.648 0.352 0.000
F60.0 Paranoid personality disorder
0.648 0.352 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.647 0.353 0.000
T43.2 Other and unspecified antidepressants
0.647 0.353 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.647 0.353 0.000
F10.9 Unspecified mental and behavioural disorder
0.646 0.354 0.000
F10.8 Other mental and behavioural disorders
0.646 0.354 0.000
F10.7 Residual and late-onset psychotic disorder
0.646 0.354 0.000
F10.6 Amnesic syndrome
0.646 0.354 0.000
F10.5 Psychotic disorder
0.646 0.354 0.000
H44 Disorders of globe
0.646 0.354 0.000
E40-E46 Malnutrition
0.645 0.355 0.000
I44.0 Atrioventricular block, first degree
0.645 0.355 0.000
I89.0 Lymphoedema, not elsewhere classified
0.644 0.356 0.000
F41.8 Other specified anxiety disorders
0.644 0.356 0.000
F41.3 Other mixed anxiety disorders
0.644 0.356 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.644 0.356 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.643 0.357 0.000
W00-W19 Falls
0.643 0.357 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.642 0.358 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.642 0.358 0.000
T91 Sequelae of injuries of neck and trunk
0.642 0.358 0.000
M84 Disorders of continuity of bone
0.642 0.358 0.000
S06.9 Intracranial injury, unspecified
0.642 0.358 0.000
S06.7 Intracranial injury with prolonged coma
0.642 0.358 0.000
S06.4 Epidural haemorrhage
0.642 0.358 0.000
S06.1 Traumatic cerebral oedema
0.642 0.358 0.000
S06.0 Concussion
0.642 0.358 0.000
I51.6 Cardiovascular disease, unspecified
0.642 0.358 0.000
I51.5 Myocardial degeneration
0.642 0.358 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.642 0.358 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.642 0.358 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.642 0.358 0.000
G43 Migraine
0.642 0.358 0.000
I49.4 Other and unspecified premature depolarisation
0.639 0.360 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.639 0.361 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.638 0.362 0.000
G95.1 Vascular myelopathies
0.638 0.362 0.000
G95.0 Syringomyelia and syringobulbia
0.638 0.362 0.000
H43 Disorders of vitreous body
0.638 0.362 0.000
I49.2 Junctional premature depolarisation
0.637 0.363 0.000
I49.1 Atrial premature depolarisation
0.637 0.363 0.000
F43.1 Posttraumatic stress disorder
0.637 0.363 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.637 0.363 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.637 0.363 0.000
G93.7 Reye's syndrome
0.636 0.364 0.000
G93.5 Compression of brain
0.636 0.364 0.000
G93.2 Benign intracranial hypertension
0.636 0.364 0.000
S29 Other and unspecified injuries of thorax
0.635 0.365 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.635 0.365 0.000
S26 Injury of heart
0.635 0.365 0.000
S25 Injury of blood vessels of thorax
0.635 0.365 0.000
S24 Injury of nerves and spinal cord at thorax level
0.635 0.365 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.635 0.365 0.000
S21 Open wound of thorax
0.635 0.365 0.000
G96 Other disorders of central nervous system
0.634 0.366 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.634 0.366 0.000
J00-J06 Acute upper respiratory infections
0.633 0.366 0.000
I49.8 Other specified cardiac arrhythmias
0.633 0.366 0.000
O36 Maternal care for other known or suspected foetal problems
0.633 0.367 0.000
S91 Open wound of ankle and foot
0.633 0.367 0.000
U89 Agent resistant to other and unspecified antibiotics
0.633 0.367 0.000
E29 Testicular dysfunction
0.633 0.367 0.000
S69.9 Unspecified injury of wrist and hand
0.632 0.368 0.000
O69.8 Labour and delivery complicated by other cord complications
0.632 0.368 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.632 0.368 0.000
G71 Primary disorders of muscles
0.632 0.368 0.000
S02 Fracture of skull and facial bones
0.631 0.369 0.000
O72.1 Other immediate postpartum haemorrhage
0.631 0.369 0.000
S89 Other and unspecified injuries of lower leg
0.631 0.369 0.000
S60.7 Multiple superficial injuries of wrist and hand
0.631 0.369 0.000
S60.2 Contusion of other parts of wrist and hand
0.631 0.369 0.000
S60.1 Contusion of finger(s) with damage to nail
0.631 0.369 0.000
S60.0 Contusion of finger(s) without damage to nail
0.631 0.369 0.000
S42.40 Fracture of lower end of humerus (closed)
0.630 0.369 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.630 0.370 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.630 0.370 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.630 0.370 0.000
I65.1 Occlusion and stenosis of basilar artery
0.630 0.370 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.630 0.370 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.630 0.370 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.629 0.370 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.629 0.370 0.000
I67.5 Moyamoya disease
0.629 0.370 0.000
I67.4 Hypertensive encephalopathy
0.629 0.370 0.000
I67.3 Progressive vascular leukoencephalopathy
0.629 0.370 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.629 0.370 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.629 0.371 0.000
S37 Injury of urinary and pelvic organs
0.629 0.371 0.000
S36 Injury of intra-abdominal organs
0.629 0.371 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.629 0.371 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.629 0.371 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.629 0.371 0.000
S31 Open wound of abdomen, lower back and pelvis
0.629 0.371 0.000
Chapter VIII Diseases of the ear and mastoid process
0.629 0.371 0.000
S90 Superficial injury of ankle and foot
0.629 0.371 0.000
S80 Superficial injury of lower leg
0.629 0.371 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.627 0.372 0.000
O32.1 Maternal care for breech presentation
0.627 0.373 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.627 0.373 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.626 0.373 0.000
G72 Other myopathies
0.625 0.375 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.624 0.375 0.000
T40.8 Lysergide [LSD]
0.624 0.375 0.000
T40.7 Cannabis (derivatives)
0.624 0.375 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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