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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17368073
log Bayes Factor = 7.77278
Chromosome 1   position 77,222,172  (GRCh37) Explore rs17368073 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.997 0.003 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.996 0.004 0.000
J45 Asthma
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.992 0.008 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.988 0.012 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.987 0.013 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.987 0.013 0.000
J09-J18 Influenza and pneumonia
0.986 0.014 0.000
M20-M25 Other joint disorders
0.983 0.017 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.982 0.018 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.975 0.025 0.000
D60-D64 Aplastic and other anaemias
0.974 0.026 0.000
M25 Other joint disorders, not elsewhere classified
0.967 0.033 0.000
J45.9 Asthma, unspecified
0.960 0.040 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.959 0.041 0.000
Chapter II Neoplasms
0.955 0.045 0.000
J45.0 Predominantly allergic asthma
0.953 0.047 0.000
E50-E64 Other nutritional deficiencies
0.951 0.049 0.000
A30-A49 Other bacterial diseases
0.947 0.053 0.000
M31 Other necrotising vasculopathies
0.946 0.054 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.945 0.055 0.000
M21 Other acquired deformities of limbs
0.944 0.056 0.000
A00-A09 Intestinal infectious diseases
0.938 0.062 0.000
D46 Myelodysplastic syndromes
0.937 0.063 0.000
M25.5 Pain in joint
0.933 0.067 0.000
T43.2 Other and unspecified antidepressants
0.931 0.069 0.000
D69 Purpura and other haemorrhagic conditions
0.931 0.069 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.928 0.072 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.927 0.073 0.000
E70-E90 Metabolic disorders
0.923 0.077 0.000
J18 Pneumonia, organism unspecified
0.923 0.077 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.921 0.079 0.000
M31.6 Other giant cell arteritis
0.916 0.084 0.000
D64 Other anaemias
0.915 0.085 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.914 0.086 0.000
J18.1 Lobar pneumonia, unspecified
0.908 0.092 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.907 0.093 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.907 0.093 0.000
Q60-Q64 Congenital malformations of the urinary system
0.904 0.096 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.901 0.099 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.898 0.102 0.000
B15-B19 Viral hepatitis
0.896 0.104 0.000
E53 Deficiency of other B group vitamins
0.892 0.108 0.000
Chapter XX External causes of morbidity and mortality
0.891 0.109 0.000
A40 Streptococcal septicaemia
0.886 0.114 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.884 0.116 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.884 0.116 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.880 0.120 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.879 0.121 0.000
J17 Pneumonia in diseases classified elsewhere
0.876 0.124 0.000
D69.6 Thrombocytopenia, unspecified
0.874 0.126 0.000
E20-E35 Disorders of other endocrine glands
0.874 0.126 0.000
D64.9 Anaemia, unspecified
0.873 0.127 0.000
E86 Volume depletion
0.869 0.131 0.000
A49 Bacterial infection of unspecified site
0.868 0.132 0.000
M50-M54 Other dorsopathies
0.867 0.133 0.000
C64-C68 Malignant neoplasms of urinary tract
0.867 0.133 0.000
C91 Lymphoid leukaemia
0.865 0.135 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.858 0.142 0.000
S70-S79 Injuries to the hip and thigh
0.856 0.144 0.000
C79 Secondary malignant neoplasm of other sites
0.856 0.144 0.000
D80-D89 Certain disorders involving the immune mechanism
0.853 0.147 0.000
T40.2 Other opioids
0.853 0.147 0.000
E53.8 Deficiency of other specified B group vitamins
0.851 0.149 0.000
B25-B34 Other viral diseases
0.847 0.153 0.000
E88 Other metabolic disorders
0.845 0.155 0.000
M21.3 Wrist or foot drop (acquired)
0.839 0.161 0.000
T00-T07 Injuries involving multiple body regions
0.839 0.161 0.000
J42 Unspecified chronic bronchitis
0.839 0.161 0.000
M25.4 Effusion of joint
0.838 0.162 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.836 0.164 0.000
E40-E46 Malnutrition
0.836 0.164 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.835 0.165 0.000
D63.0 Anaemia in neoplastic disease
0.834 0.166 0.000
E55 Vitamin D deficiency
0.833 0.167 0.000
C91.1 Chronic lymphocytic leukaemia
0.833 0.167 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.833 0.167 0.000
M25.51 Pain in joint (Shoulder region)
0.829 0.171 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.824 0.176 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.823 0.177 0.000
B50-B64 Protozoal diseases
0.823 0.177 0.000
Q61 Cystic kidney disease
0.823 0.177 0.000
T42.4 Benzodiazepines
0.820 0.180 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.820 0.180 0.000
M25.59 Pain in joint (Site unspecified)
0.818 0.182 0.000
M91-M94 Chondropathies
0.818 0.182 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.814 0.186 0.000
M25.8 Other specified joint disorders
0.811 0.189 0.000
M54 Dorsalgia
0.811 0.189 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.810 0.190 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.809 0.191 0.000
S00-S09 Injuries to the head
0.808 0.192 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.808 0.192 0.000
T39.1 4-Aminophenol derivatives
0.806 0.194 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.806 0.194 0.000
J11 Influenza, virus not identified
0.802 0.198 0.000
E16 Other disorders of pancreatic internal secretion
0.800 0.200 0.000
M54.9 Dorsalgia, unspecified
0.798 0.202 0.000
M21.0 Valgus deformity, not elsewhere classified
0.797 0.203 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.796 0.203 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.795 0.205 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.795 0.205 0.000
J95-J99 Other diseases of the respiratory system
0.794 0.206 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.794 0.206 0.000
S70 Superficial injury of hip and thigh
0.794 0.206 0.000
A49.8 Other bacterial infections of unspecified site
0.788 0.212 0.000
M60-M63 Disorders of muscles
0.788 0.212 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.786 0.214 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.786 0.214 0.000
B15 Acute hepatitis A
0.786 0.214 0.000
S09 Other and unspecified injuries of head
0.784 0.216 0.000
D46.7 Other myelodysplastic syndromes
0.783 0.217 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.781 0.219 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.778 0.222 0.000
M80-M85 Disorders of bone density and structure
0.778 0.222 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.776 0.224 0.000
J43 Emphysema
0.775 0.225 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.775 0.225 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.775 0.225 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.774 0.226 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.774 0.226 0.000
Chapter XXII Codes for special purposes
0.773 0.227 0.000
M33 Dermatopolymyositis
0.772 0.228 0.000
A40.8 Other streptococcal septicaemia
0.772 0.228 0.000
S60-S69 Injuries to the wrist and hand
0.770 0.230 0.000
Q50-Q56 Congenital malformations of genital organs
0.770 0.230 0.000
C66 Malignant neoplasm of ureter
0.767 0.233 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.765 0.235 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.764 0.236 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.764 0.236 0.000
M25.54 Pain in joint (Hand)
0.763 0.237 0.000
S09.9 Unspecified injury of head
0.761 0.239 0.000
J10 Influenza due to identified influenza virus
0.760 0.240 0.000
T66-T78 Other and unspecified effects of external causes
0.760 0.240 0.000
J17.3 Pneumonia in parasitic diseases
0.760 0.240 0.000
Q61.3 Polycystic kidney, unspecified
0.759 0.241 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.759 0.241 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.758 0.242 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.756 0.244 0.000
M21.4 Flat foot [pes planus] (acquired)
0.756 0.244 0.000
T79-T79 Certain early complications of trauma
0.756 0.244 0.000
D46.2 Refractory anaemia with excess of blasts
0.750 0.250 0.000
M25.3 Other instability of joint
0.750 0.250 0.000
A49.0 Staphylococcal infection, unspecified
0.750 0.250 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.750 0.250 0.000
E55.9 Vitamin D deficiency, unspecified
0.749 0.251 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.746 0.254 0.000
D37.4 Colon
0.746 0.254 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.744 0.256 0.000
E16.2 Hypoglycaemia, unspecified
0.744 0.256 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.743 0.257 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.743 0.257 0.000
M34 Systemic sclerosis
0.743 0.257 0.000
D66 Hereditary factor VIII deficiency
0.742 0.258 0.000
T42.1 Iminostilbenes
0.742 0.258 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.740 0.260 0.000
D55-D59 Haemolytic anaemias
0.739 0.261 0.000
M50 Cervical disk disorders
0.736 0.264 0.000
C07 Malignant neoplasm of parotid gland
0.735 0.265 0.000
C67 Malignant neoplasm of bladder
0.734 0.266 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.734 0.266 0.000
B18 Chronic viral hepatitis
0.732 0.268 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.731 0.269 0.000
C05 Malignant neoplasm of palate
0.731 0.269 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.730 0.269 0.000
J14 Pneumonia due to Haemophilus influenzae
0.729 0.271 0.000
A40.9 Streptococcal septicaemia, unspecified
0.729 0.271 0.000
C01 Malignant neoplasm of base of tongue
0.729 0.271 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.729 0.271 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.728 0.272 0.000
M21.2 Flexion deformity
0.727 0.272 0.000
E46 Unspecified protein-energy malnutrition
0.727 0.273 0.000
C84.5 Other and unspecified T-cell lymphomas
0.727 0.273 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.726 0.273 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.724 0.276 0.000
M70-M79 Other soft tissue disorders
0.724 0.276 0.000
M25.52 Pain in joint (Upper arm)
0.724 0.276 0.000
Q80-Q89 Other congenital malformations
0.722 0.278 0.000
V40-V49 Car occupant injured in transport accident
0.722 0.278 0.000
E85 Amyloidosis
0.722 0.278 0.000
D61 Other aplastic anaemias
0.721 0.279 0.000
D37.2 Small intestine
0.720 0.280 0.000
M32 Systemic lupus erythematosus
0.719 0.280 0.000
X60-X84 Intentional self-harm
0.719 0.280 0.000
J98 Other respiratory disorders
0.718 0.282 0.000
M21.1 Varus deformity, not elsewhere classified
0.718 0.282 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
S50-S59 Injuries to the elbow and forearm
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
T36 Poisoning by systemic antibiotics
0.716 0.284 0.000
A48 Other bacterial diseases, not elsewhere classified
0.716 0.284 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.716 0.284 0.000
T92 Sequelae of injuries of upper limb
0.713 0.287 0.000
J45.8 Mixed asthma
0.712 0.288 0.000
J45.1 Nonallergic asthma
0.712 0.288 0.000
J15.2 Pneumonia due to staphylococcus
0.712 0.288 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.711 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.711 0.289 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.289 0.000
A75-A79 Rickettsioses
0.711 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.289 0.000
A65-A69 Other spirochaetal diseases
0.711 0.289 0.000
A20-A28 Certain zoonotic bacterial diseases
0.711 0.289 0.000
A15-A19 Tuberculosis
0.711 0.289 0.000
S80-S89 Injuries to the knee and lower leg
0.711 0.289 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.710 0.290 0.000
E73 Lactose intolerance
0.709 0.291 0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.709 0.291 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.707 0.292 0.000
Q35-Q37 Cleft lip and cleft palate
0.707 0.292 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.707 0.292 0.000
A40.3 Septicaemia due to Streptococcus pneumoniae
0.707 0.292 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.707 0.293 0.000
J12 Viral pneumonia, not elsewhere classified
0.707 0.293 0.000
J09 Influenza due to certain identified influenza virus
0.707 0.293 0.000
M25.84 Other specified joint disorders (Hand)
0.707 0.293 0.000
Y43 Primarily systemic agents
0.707 0.293 0.000
B15.9 Hepatitis A without hepatic coma
0.706 0.293 0.000
Y45.1 Salicylates
0.706 0.294 0.000
A07 Other protozoal intestinal diseases
0.706 0.294 0.000
D50-D53 Nutritional anaemias
0.706 0.294 0.000
B19 Unspecified viral hepatitis
0.705 0.295 0.000
Y45.0 Opioids and related analgesics
0.705 0.295 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.704 0.295 0.000
M30 Polyarteritis nodosa and related conditions
0.704 0.295 0.000
M85 Other disorders of bone density and structure
0.704 0.296 0.000
T43.9 Psychotropic drug, unspecified
0.704 0.296 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.704 0.296 0.000
T43.6 Psychostimulants with abuse potential
0.704 0.296 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.704 0.296 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.704 0.296 0.000
Q62.5 Duplication of ureter
0.703 0.297 0.000
B59 Pneumocystosis
0.702 0.298 0.000
T40.6 Other and unspecified narcotics
0.701 0.299 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.699 0.300 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.699 0.301 0.000
B99-B99 Other infectious diseases
0.699 0.301 0.000
E21.0 Primary hyperparathyroidism
0.699 0.301 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.698 0.302 0.000
S62 Fracture at wrist and hand level
0.698 0.302 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.697 0.303 0.000
M65-M68 Disorders of synovium and tendon
0.697 0.303 0.000
Q27 Other congenital malformations of peripheral vascular system
0.696 0.304 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.696 0.304 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.695 0.305 0.000
B34 Viral infection of unspecified site
0.695 0.305 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.695 0.305 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.694 0.306 0.000
M25.2 Flail joint
0.693 0.307 0.000
M25.1 Fistula of joint
0.693 0.307 0.000
Q18 Other congenital malformations of face and neck
0.693 0.307 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.692 0.308 0.000
E88.2 Lipomatosis, not elsewhere classified
0.690 0.310 0.000
M00-M03 Infectious arthropathies
0.690 0.310 0.000
T02 Fractures involving multiple body regions
0.689 0.310 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.689 0.311 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.689 0.311 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.688 0.312 0.000
M25.9 Joint disorder, unspecified
0.688 0.312 0.000
D67 Hereditary factor IX deficiency
0.687 0.313 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.687 0.313 0.000
E23 Hypofunction and other disorders of pituitary gland
0.686 0.313 0.000
C09 Malignant neoplasm of tonsil
0.685 0.314 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.684 0.315 0.000
Q61.2 Polycystic kidney, adult type
0.684 0.315 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.684 0.316 0.000
D69.5 Secondary thrombocytopenia
0.684 0.316 0.000
D80 Immunodeficiency with predominantly antibody defects
0.684 0.316 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.683 0.317 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.682 0.318 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.682 0.318 0.000
E63 Other nutritional deficiencies
0.682 0.318 0.000
E56 Other vitamin deficiencies
0.682 0.318 0.000
E51 Thiamine deficiency
0.682 0.318 0.000
E50 Vitamin A deficiency
0.682 0.318 0.000
E60 Dietary zinc deficiency
0.682 0.318 0.000
E59 Dietary selenium deficiency
0.682 0.318 0.000
E58 Dietary calcium deficiency
0.682 0.318 0.000
E54 Ascorbic acid deficiency
0.682 0.318 0.000
E52 Niacin deficiency [pellagra]
0.682 0.318 0.000
M94 Other disorders of cartilage
0.680 0.320 0.000
A44 Bartonellosis
0.679 0.321 0.000
A43 Nocardiosis
0.679 0.321 0.000
A42 Actinomycosis
0.679 0.321 0.000
A39 Meningococcal infection
0.679 0.321 0.000
A37 Whooping cough
0.679 0.321 0.000
A36 Diphtheria
0.679 0.321 0.000
A32 Listeriosis
0.679 0.321 0.000
A31 Infection due to other mycobacteria
0.679 0.321 0.000
A30 Leprosy [Hansen's disease]
0.679 0.321 0.000
A38 Scarlet fever
0.679 0.321 0.000
A35 Other tetanus
0.679 0.321 0.000
A34 Obstetrical tetanus
0.679 0.321 0.000
A33 Tetanus neonatorum
0.679 0.321 0.000
M31.9 Necrotising vasculopathy, unspecified
0.678 0.321 0.000
M31.8 Other specified necrotising vasculopathies
0.678 0.321 0.000
M31.7 Microscopic polyangiitis
0.678 0.321 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.678 0.321 0.000
M31.2 Lethal midline granuloma
0.678 0.321 0.000
M31.1 Thrombotic microangiopathy
0.678 0.321 0.000
M31.0 Hypersensitivity angiitis
0.678 0.321 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.678 0.322 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.678 0.322 0.000
Q24 Other congenital malformations of heart
0.678 0.322 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.677 0.323 0.000
M21.9 Acquired deformity of limb, unspecified
0.677 0.323 0.000
M21.8 Other specified acquired deformities of limbs
0.677 0.323 0.000
M21.7 Unequal limb length (acquired)
0.677 0.323 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.677 0.323 0.000
S90-S99 Injuries to the ankle and foot
0.677 0.323 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.676 0.324 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.674 0.326 0.000
M25.43 Effusion of joint (Forearm)
0.673 0.326 0.000
A06 Amoebiasis
0.672 0.327 0.000
A05 Other bacterial foodborne intoxications
0.672 0.327 0.000
A03 Shigellosis
0.672 0.327 0.000
A01 Typhoid and paratyphoid fevers
0.672 0.327 0.000
A00 Cholera
0.672 0.327 0.000
Q00-Q07 Congenital malformations of the nervous system
0.672 0.327 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.672 0.328 0.000
A40.0 Septicaemia due to streptococcus, group A
0.672 0.328 0.000
C79.2 Secondary malignant neoplasm of skin
0.672 0.328 0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.672 0.328 0.000
D46.5 Refractory anaemia with multi-lineage dysplasia
0.672 0.328 0.000
D46.4 Refractory anaemia, unspecified
0.672 0.328 0.000
D46.3 Refractory anaemia with excess of blasts with transformation
0.672 0.328 0.000
D46.1 Refractory anaemia with sideroblasts
0.672 0.328 0.000
D46.0 Refractory anaemia without sideroblasts, so stated
0.672 0.328 0.000
M25.53 Pain in joint (Forearm)
0.671 0.329 0.000
E61 Deficiency of other nutrient elements
0.671 0.329 0.000
B65-B83 Helminthiases
0.670 0.330 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.670 0.330 0.000
M25.40 Effusion of joint (Multiple sites)
0.670 0.330 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.670 0.330 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.670 0.330 0.000
Chapter VIII Diseases of the ear and mastoid process
0.670 0.330 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.669 0.331 0.000
M25.58 Pain in joint (Other)
0.669 0.331 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.668 0.332 0.000
B25 Cytomegaloviral disease
0.668 0.332 0.000
D69.9 Haemorrhagic condition, unspecified
0.667 0.332 0.000
D69.8 Other specified haemorrhagic conditions
0.667 0.332 0.000
D69.4 Other primary thrombocytopenia
0.667 0.332 0.000
D69.2 Other nonthrombocytopenic purpura
0.667 0.332 0.000
D69.1 Qualitative platelet defects
0.667 0.332 0.000
D69.0 Allergic purpura
0.667 0.332 0.000
S70.8 Other superficial injuries of hip and thigh
0.666 0.334 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.666 0.334 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.666 0.334 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.666 0.334 0.000
T42.3 Barbiturates
0.666 0.334 0.000
T42.2 Succinimides and oxazolidinediones
0.666 0.334 0.000
T42.0 Hydantoin derivatives
0.666 0.334 0.000
M85.8 Other specified disorders of bone density and structure
0.665 0.335 0.000
J60-J70 Lung diseases due to external agents
0.665 0.335 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.664 0.336 0.000
Y65 Other misadventures during surgical and medical care
0.664 0.336 0.000
D62 Acute posthaemorrhagic anaemia
0.663 0.337 0.000
S71 Open wound of hip and thigh
0.663 0.337 0.000
E84 Cystic fibrosis
0.662 0.338 0.000
E79 Disorders of purine and pyrimidine metabolism
0.662 0.338 0.000
E77 Disorders of glycoprotein metabolism
0.662 0.338 0.000
E76 Disorders of glycosaminoglycan metabolism
0.662 0.338 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.662 0.338 0.000
E74 Other disorders of carbohydrate metabolism
0.662 0.338 0.000
E72 Other disorders of amino-acid metabolism
0.662 0.338 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.662 0.338 0.000
E70 Disorders of aromatic amino-acid metabolism
0.662 0.338 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.662 0.338 0.000
J18.8 Other pneumonia, organism unspecified
0.661 0.338 0.000
J18.2 Hypostatic pneumonia, unspecified
0.661 0.338 0.000
W50-W64 Exposure to animate mechanical forces
0.661 0.339 0.000
M31.3 Wegener's granulomatosis
0.661 0.339 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.661 0.339 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.661 0.339 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.660 0.340 0.000
M54.2 Cervicalgia
0.660 0.340 0.000
E83 Disorders of mineral metabolism
0.660 0.340 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.659 0.341 0.000
J15.9 Bacterial pneumonia, unspecified
0.659 0.341 0.000
T63 Toxic effect of contact with venomous animals
0.659 0.341 0.000
T00 Superficial injuries involving multiple body regions
0.657 0.343 0.000
A02 Other Salmonella infections
0.657 0.343 0.000
D64.8 Other specified anaemias
0.656 0.344 0.000
D64.4 Congenital dyserythropoietic anaemia
0.656 0.344 0.000
D64.3 Other sideroblastic anaemias
0.656 0.344 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.656 0.344 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.656 0.344 0.000
D64.0 Hereditary sideroblastic anaemia
0.656 0.344 0.000
B02 Zoster [herpes zoster]
0.656 0.344 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.656 0.344 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.655 0.345 0.000
T40.8 Lysergide [LSD]
0.655 0.345 0.000
T40.7 Cannabis (derivatives)
0.655 0.345 0.000
T40.5 Cocaine
0.655 0.345 0.000
T40.3 Methadone
0.655 0.345 0.000
T40.1 Heroin
0.655 0.345 0.000
T40.0 Opium
0.655 0.345 0.000
T23 Burn and corrosion of wrist and hand
0.655 0.345 0.000
E24 Cushing's syndrome
0.655 0.345 0.000
M54.6 Pain in thoracic spine
0.654 0.346 0.000
M25.46 Effusion of joint (Lower leg)
0.652 0.348 0.000
T20 Burn and corrosion of head and neck
0.651 0.349 0.000
J98.4 Other disorders of lung
0.651 0.349 0.000
C04 Malignant neoplasm of floor of mouth
0.651 0.349 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.650 0.350 0.000
C95 Leukaemia of unspecified cell type
0.650 0.350 0.000
C94 Other leukaemias of specified cell type
0.650 0.350 0.000
C93 Monocytic leukaemia
0.650 0.350 0.000
C86 Other specified types of T/NK-cell lymphoma
0.650 0.350 0.000
E20 Hypoparathyroidism
0.650 0.350 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.650 0.350 0.000
E80.4 Gilbert's syndrome
0.649 0.350 0.000
E65-E68 Obesity and other hyperalimentation
0.649 0.351 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.649 0.351 0.000
Q64 Other congenital malformations of urinary system
0.648 0.352 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.648 0.352 0.000
C80 Malignant neoplasm without specification of site
0.648 0.352 0.000
A04 Other bacterial intestinal infections
0.647 0.352 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.646 0.354 0.000
C13 Malignant neoplasm of hypopharynx
0.646 0.354 0.000
C11 Malignant neoplasm of nasopharynx
0.646 0.354 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.646 0.354 0.000
C03 Malignant neoplasm of gum
0.646 0.354 0.000
C00 Malignant neoplasm of lip
0.646 0.354 0.000
C12 Malignant neoplasm of pyriform sinus
0.646 0.354 0.000
J40 Bronchitis, not specified as acute or chronic
0.645 0.355 0.000
M62 Other disorders of muscle
0.645 0.355 0.000
D63.1 Anaemia in other chronic diseases classified elsewhere
0.644 0.356 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.642 0.358 0.000
Chapter XXI Factors influencing health status and contact with health services
0.642 0.358 0.000
M40-M43 Deforming dorsopathies
0.642 0.358 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.642 0.358 0.000
S05 Injury of eye and orbit
0.641 0.359 0.000
T39.0 Salicylates
0.641 0.359 0.000
S70.0 Contusion of hip
0.640 0.360 0.000
E53.9 Vitamin B deficiency, unspecified
0.640 0.360 0.000
E53.1 Pyridoxine deficiency
0.640 0.360 0.000
E53.0 Riboflavin deficiency
0.640 0.360 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.639 0.361 0.000
S10-S19 Injuries to the neck
0.639 0.361 0.000
M86-M90 Other osteopathies
0.639 0.361 0.000
M25.0 Haemarthrosis
0.639 0.361 0.000
Y35-Y36 Legal intervention and operations of war
0.638 0.361 0.000
Y10-Y34 Event of undetermined intent
0.638 0.361 0.000
Y00-Y09 Assault
0.638 0.361 0.000
X85-X99 Assault
0.638 0.361 0.000
X30-X39 Exposure to forces of nature
0.638 0.361 0.000
X10-X19 Contact with heat and hot substances
0.638 0.361 0.000
X00-X09 Exposure to smoke, fire and flames
0.638 0.361 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.638 0.361 0.000
W75-W84 Other accidental threats to breathing
0.638 0.361 0.000
W65-W74 Accidental drowning and submersion
0.638 0.361 0.000
V98-V99 Other and unspecified transport accidents
0.638 0.361 0.000
V95-V97 Air and space transport accidents
0.638 0.361 0.000
V90-V94 Water transport accidents
0.638 0.361 0.000
V70-V79 Bus occupant injured in transport accident
0.638 0.361 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.638 0.361 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.638 0.361 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.638 0.361 0.000
V01-V09 Pedestrian injured in transport accident
0.638 0.361 0.000
Q52 Other congenital malformations of female genitalia
0.638 0.362 0.000
V80-V89 Other land transport accidents
0.638 0.362 0.000
E34 Other endocrine disorders
0.638 0.362 0.000
A60 Anogenital herpesviral [herpes simplex] infections
0.637 0.362 0.000
C10 Malignant neoplasm of oropharynx
0.637 0.363 0.000
A40.2 Septicaemia due to streptococcus, group D
0.635 0.365 0.000
A40.1 Septicaemia due to streptococcus, group B
0.635 0.365 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.635 0.365 0.000
A49.1 Streptococcal infection, unspecified
0.635 0.365 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.633 0.366 0.000
T45.0 Antiallergic and antiemetic drugs
0.633 0.366 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.633 0.367 0.000
M54.3 Sciatica
0.633 0.367 0.000
C88 Malignant immunoproliferative diseases
0.632 0.368 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.631 0.369 0.000
T39.4 Antirheumatics, not elsewhere classified
0.631 0.369 0.000
T39.2 Pyrazolone derivatives
0.631 0.369 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.631 0.369 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.630 0.370 0.000
E15 Nondiabetic hypoglycaemic coma
0.630 0.370 0.000
C91.4 Hairy-cell leukaemia
0.630 0.370 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.629 0.371 0.000
B18.2 Chronic viral hepatitis C
0.629 0.371 0.000
A80-A89 Viral infections of the central nervous system
0.629 0.371 0.000
C91.0 Acute lymphoblastic leukaemia
0.628 0.371 0.000
S64 Injury of nerves at wrist and hand level
0.628 0.372 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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