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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17404153
log Bayes Factor = 3.61794
Chromosome 3   position 132,163,200  (GRCh37) Explore rs17404153 on Ensembl!
Variant rs17404153 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.001 0.999
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
I20-I25 Ischaemic heart diseases
0.000 0.010 0.990
I25.2 Old myocardial infarction
0.000 0.013 0.987
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.047 0.953
I20 Angina pectoris
0.000 0.052 0.948
I24 Other acute ischaemic heart diseases
0.000 0.059 0.941
I24.8 Other forms of acute ischaemic heart disease
0.000 0.068 0.932
I20.0 Unstable angina
0.000 0.086 0.914
I21 Acute myocardial infarction
0.000 0.132 0.868
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.180 0.820
I21.9 Acute myocardial infarction, unspecified
0.000 0.182 0.818
I25.4 Coronary artery aneurysm
0.000 0.195 0.805
I20.9 Angina pectoris, unspecified
0.000 0.233 0.767
I25.3 Aneurysm of heart
0.000 0.278 0.722
I23 Certain current complications following acute myocardial infarction
0.000 0.281 0.719
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.284 0.716
I20.1 Angina pectoris with documented spasm
0.000 0.286 0.714
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.330 0.669
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.357 0.643
Z95.1 Presence of aortocoronary bypass graft
0.000 0.361 0.639
Chapter IX Diseases of the circulatory system
0.000 0.362 0.638
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.377 0.622
I44 Atrioventricular and left bundle-branch block
0.000 0.385 0.615
I44.7 Left bundle-branch block, unspecified
0.000 0.386 0.614
I10-I15 Hypertensive diseases
0.000 0.388 0.612
I24.1 Dressler's syndrome
0.000 0.389 0.611
I30-I52 Other forms of heart disease
0.000 0.390 0.610
I25.5 Ischaemic cardiomyopathy
0.000 0.393 0.607
I42 Cardiomyopathy
0.000 0.396 0.604
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.412 0.588
I42.9 Cardiomyopathy, unspecified
0.000 0.415 0.585
I10 Essential (primary) hypertension
0.000 0.420 0.580
I74 Arterial embolism and thrombosis
0.000 0.423 0.577
I44.2 Atrioventricular block, complete
0.000 0.425 0.575
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.430 0.570
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.432 0.568
I42.0 Dilated cardiomyopathy
0.000 0.434 0.566
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.444 0.556
I20.8 Other forms of angina pectoris
0.000 0.450 0.550
I71 Aortic aneurysm and dissection
0.000 0.453 0.547
I46 Cardiac arrest
0.000 0.454 0.546
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.455 0.545
I44.6 Other and unspecified fascicular block
0.000 0.458 0.542
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.466 0.534
I22 Subsequent myocardial infarction
0.000 0.474 0.526
I23.8 Other current complications following acute myocardial infarction
0.000 0.475 0.525
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.484 0.516
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.484 0.516
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.484 0.516
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.484 0.516
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.484 0.516
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.484 0.516
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.484 0.516
I46.0 Cardiac arrest with successful resuscitation
0.000 0.492 0.508
I12 Hypertensive renal disease
0.000 0.501 0.499
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.503 0.497
I42.2 Other hypertrophic cardiomyopathy
0.000 0.505 0.495
I11 Hypertensive heart disease
0.000 0.510 0.490
I72 Other aneurysm
0.000 0.510 0.489
I45 Other conduction disorders
0.000 0.515 0.485
I71.0 Dissection of aorta [any part]
0.000 0.522 0.478
I36 Nonrheumatic tricuspid valve disorders
0.000 0.528 0.472
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.532 0.468
I00-I02 Acute rheumatic fever
0.000 0.543 0.457
I37 Pulmonary valve disorders
0.000 0.543 0.457
I42.8 Other cardiomyopathies
0.000 0.546 0.454
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.548 0.451
I74.8 Embolism and thrombosis of other arteries
0.000 0.554 0.446
I72.4 Aneurysm of artery of lower extremity
0.000 0.556 0.444
I44.5 Left posterior fascicular block
0.000 0.559 0.441
I44.4 Left anterior fascicular block
0.000 0.559 0.441
I13 Hypertensive heart and renal disease
0.000 0.561 0.439
I52 Other heart disorders in diseases classified elsewhere
0.000 0.562 0.437
I48 Atrial fibrillation and flutter
0.000 0.562 0.437
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.562 0.437
I41 Myocarditis in diseases classified elsewhere
0.000 0.562 0.437
I40 Acute myocarditis
0.000 0.562 0.437
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.562 0.437
I32 Pericarditis in diseases classified elsewhere
0.000 0.562 0.437
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.567 0.433
I42.5 Other restrictive cardiomyopathy
0.000 0.567 0.433
I42.4 Endocardial fibroelastosis
0.000 0.567 0.433
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.567 0.433
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.569 0.431
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.569 0.430
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.571 0.429
I12.9 Hypertensive renal disease without renal failure
0.000 0.577 0.423
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.580 0.420
I72.0 Aneurysm of carotid artery
0.000 0.583 0.417
I74.5 Embolism and thrombosis of iliac artery
0.000 0.583 0.417
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.586 0.414
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.586 0.414
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.586 0.414
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.587 0.413
I45.8 Other specified conduction disorders
0.000 0.587 0.413
I51 Complications and ill-defined descriptions of heart disease
0.000 0.593 0.407
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.598 0.402
I15 Secondary hypertension
0.000 0.601 0.399
I44.1 Atrioventricular block, second degree
0.000 0.601 0.399
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.607 0.393
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.607 0.392
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.607 0.392
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.607 0.392
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.607 0.392
I46.1 Sudden cardiac death, so described
0.000 0.608 0.392
I44.3 Other and unspecified atrioventricular block
0.000 0.618 0.382
I45.9 Conduction disorder, unspecified
0.000 0.621 0.379
I45.5 Other specified heart block
0.000 0.621 0.379
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.624 0.376
I45.2 Bifascicular block
0.000 0.625 0.375
I21.4 Acute subendocardial myocardial infarction
0.000 0.626 0.374
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.628 0.372
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.631 0.369
I46.9 Cardiac arrest, unspecified
0.000 0.636 0.364
I45.4 Nonspecific intraventricular block
0.000 0.637 0.363
I45.3 Trifascicular block
0.000 0.642 0.358
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.649 0.351
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.649 0.351
I72.1 Aneurysm of artery of upper extremity
0.000 0.649 0.351
I12.0 Hypertensive renal disease with renal failure
0.000 0.651 0.349
I45.0 Right fascicular block
0.000 0.652 0.347
I37.1 Pulmonary valve insufficiency
0.000 0.653 0.347
I30 Acute pericarditis
0.000 0.657 0.343
I45.6 Preexcitation syndrome
0.000 0.658 0.342
I05-I09 Chronic rheumatic heart diseases
0.000 0.660 0.339
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.662 0.338
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.662 0.338
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.662 0.338
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.662 0.338
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.663 0.337
I72.9 Aneurysm of unspecified site
0.000 0.664 0.336
I51.4 Myocarditis, unspecified
0.000 0.664 0.336
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.666 0.334
I77 Other disorders of arteries and arterioles
0.000 0.666 0.334
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.668 0.332
I51.6 Cardiovascular disease, unspecified
0.000 0.669 0.331
I33 Acute and subacute endocarditis
0.000 0.669 0.330
Z95.4 Presence of other heart-valve replacement
0.000 0.672 0.328
I02 Rheumatic chorea
0.000 0.672 0.328
I01 Rheumatic fever with heart involvement
0.000 0.672 0.328
I00 Rheumatic fever without mention of heart involvement
0.000 0.672 0.328
I37.9 Pulmonary valve disorder, unspecified
0.000 0.672 0.328
I37.8 Other pulmonary valve disorders
0.000 0.672 0.328
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.672 0.328
I37.0 Pulmonary valve stenosis
0.000 0.672 0.328
I72.3 Aneurysm of iliac artery
0.000 0.675 0.325
I72.8 Aneurysm of other specified arteries
0.000 0.679 0.321
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.685 0.315
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.685 0.315
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.685 0.315
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.685 0.315
I51.8 Other ill-defined heart diseases
0.000 0.685 0.315
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.686 0.314
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.686 0.314
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.686 0.314
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.686 0.314
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.686 0.314
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.686 0.314
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.686 0.314
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.686 0.314
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.686 0.314
I40.9 Acute myocarditis, unspecified
0.000 0.686 0.314
I40.8 Other acute myocarditis
0.000 0.686 0.314
I40.1 Isolated myocarditis
0.000 0.686 0.314
I40.0 Infective myocarditis
0.000 0.686 0.314
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.686 0.314
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.686 0.314
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.686 0.314
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.686 0.314
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.686 0.314
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.686 0.314
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.686 0.314
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.686 0.314
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.686 0.314
I48.4 Atypical atrial flutter
0.000 0.686 0.314
I48.3 Typical atrial flutter
0.000 0.686 0.314
I48.2 Chronic atrial fibrillation
0.000 0.686 0.314
I48.1 Persistent atrial fibrillation
0.000 0.686 0.314
I48.0 Paroxysmal atrial fibrillation
0.000 0.686 0.314
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.686 0.314
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.686 0.314
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.686 0.314
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.688 0.312
I49 Other cardiac arrhythmias
0.000 0.689 0.311
I31 Other diseases of pericardium
0.000 0.690 0.310
I49.8 Other specified cardiac arrhythmias
0.000 0.703 0.297
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.704 0.296
I51.5 Myocardial degeneration
0.000 0.708 0.292
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.708 0.292
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.708 0.292
I44.0 Atrioventricular block, first degree
0.000 0.711 0.289
I51.9 Heart disease, unspecified
0.000 0.712 0.288
I15.9 Seconday hypertension, unspecified
0.000 0.713 0.287
I15.8 Other secondary hypertension
0.000 0.714 0.286
I15.2 Hypertension secondary to endocrine disorders
0.000 0.714 0.286
I15.0 Renovascular hypertension
0.000 0.714 0.286
I77.1 Stricture of artery
0.000 0.716 0.284
I22.8 Subsequent myocardial infarction of other sites
0.000 0.717 0.282
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.718 0.282
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.735 0.265
I79.1 Aortitis in diseases classified elsewhere
0.000 0.735 0.265
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.735 0.265
I07 Rheumatic tricuspid valve diseases
0.000 0.738 0.262
I78 Diseases of capillaries
0.000 0.740 0.259
Z95.3 Presence of xenogenic heart valve
0.000 0.740 0.259
I09 Other rheumatic heart diseases
0.000 0.746 0.254
I70 Atherosclerosis
0.000 0.746 0.253
I51.0 Cardiac septal defect, acquired
0.000 0.748 0.251
I38 Endocarditis, valve unspecified
0.000 0.749 0.250
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.753 0.247
I97.1 Other functional disturbances following cardiac surgery
0.000 0.754 0.246
I30.8 Other forms of acute pericarditis
0.000 0.754 0.246
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.754 0.246
I15.1 Hypertension secondary to other renal disorders
0.000 0.754 0.246
I42.6 Alcoholic cardiomyopathy
0.001 0.756 0.243
I77.6 Arteritis, unspecified
0.000 0.757 0.243
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.760 0.240
I30.1 Infective pericarditis
0.000 0.761 0.239
I77.5 Necrosis of artery
0.000 0.761 0.239
I77.4 Coeliac artery compression syndrome
0.000 0.761 0.239
I77.3 Arterial fibromuscular dysplasia
0.000 0.761 0.239
I77.2 Rupture of artery
0.000 0.761 0.239
I72.2 Aneurysm of renal artery
0.001 0.763 0.237
I33.9 Acute endocarditis, unspecified
0.000 0.763 0.237
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.764 0.235
I01.8 Other acute rheumatic heart disease
0.000 0.764 0.235
I01.2 Acute rheumatic myocarditis
0.000 0.764 0.235
I01.1 Acute rheumatic endocarditis
0.000 0.764 0.235
I01.0 Acute rheumatic pericarditis
0.000 0.764 0.235
I02.9 Rheumatic chorea without heart involvement
0.000 0.764 0.235
I02.0 Rheumatic chorea with heart involvement
0.000 0.764 0.235
I49.0 Ventricular fibrillation and flutter
0.000 0.769 0.231
I08 Multiple valve diseases
0.000 0.770 0.230
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.771 0.229
I77.0 Arteriovenous fistula, acquired
0.000 0.772 0.228
Z95.0 Presence of cardiac pacemaker
0.000 0.772 0.228
I21.2 Acute transmural myocardial infarction of other sites
0.001 0.774 0.225
I31.9 Disease of pericardium, unspecified
0.000 0.774 0.226
I49.2 Junctional premature depolarisation
0.000 0.777 0.223
I31.8 Other specified diseases of pericardium
0.000 0.777 0.223
I31.2 Haemopericardium, not elsewhere classified
0.000 0.777 0.223
I31.0 Chronic adhesive pericarditis
0.000 0.777 0.223
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.780 0.220
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.787 0.212
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.788 0.212
I97.0 Postcardiotomy syndrome
0.000 0.788 0.212
I49.1 Atrial premature depolarisation
0.000 0.791 0.209
I07.1 Tricuspid insufficiency
0.000 0.794 0.206
I06 Rheumatic aortic valve diseases
0.000 0.795 0.204
I99 Other and unspecified disorders of circulatory system
0.000 0.796 0.203
I77.8 Other specified disorders of arteries and arterioles
0.000 0.801 0.198
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.802 0.198
I31.1 Chronic constrictive pericarditis
0.000 0.807 0.193
I09.9 Rheumatic heart disease, unspecified
0.000 0.807 0.193
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.811 0.189
I07.9 Tricuspid valve disease, unspecified
0.000 0.812 0.188
I07.8 Other tricuspid valve diseases
0.000 0.812 0.188
I07.2 Tricuspid stenosis with insufficiency
0.000 0.812 0.188
I07.0 Tricuspid stenosis
0.000 0.812 0.188
I78.9 Disease of capillaries, unspecified
0.000 0.814 0.186
I08.8 Other multiple valve diseases
0.000 0.814 0.186
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.814 0.185
I09.8 Other specified rheumatic heart diseases
0.000 0.818 0.182
I09.2 Chronic rheumatic pericarditis
0.000 0.818 0.182
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.818 0.182
I09.0 Rheumatic myocarditis
0.000 0.818 0.182
I70.9 Generalised and unspecified atherosclerosis
0.001 0.818 0.182
I49.3 Ventricular premature depolarisation
0.000 0.821 0.179
Z95.2 Presence of prosthetic heart valve
0.000 0.824 0.176
I70.1 Atherosclerosis of renal artery
0.001 0.824 0.176
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.825 0.174
I70.8 Atherosclerosis of other arteries
0.001 0.836 0.164
I30.9 Acute pericarditis, unspecified
0.000 0.836 0.164
I78.8 Other diseases of capillaries
0.000 0.838 0.161
I28 Other diseases of pulmonary vessels
0.000 0.839 0.160
I47 Paroxysmal tachycardia
0.000 0.842 0.158
N81.1 Cystocele
0.000 0.844 0.156
I05 Rheumatic mitral valve diseases
0.000 0.845 0.155
I73 Other peripheral vascular diseases
0.000 0.847 0.153
I70.0 Atherosclerosis of aorta
0.001 0.848 0.151
N81 Female genital prolapse
0.000 0.848 0.152
N81.8 Other female genital prolapse
0.000 0.849 0.151
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.853 0.146
I06.8 Other rheumatic aortic valve diseases
0.000 0.853 0.146
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.853 0.146
I06.0 Rheumatic aortic stenosis
0.000 0.853 0.146
I31.3 Pericardial effusion (noninflammatory)
0.000 0.857 0.143
N81.5 Vaginal enterocele
0.000 0.859 0.141
I49.4 Other and unspecified premature depolarisation
0.000 0.859 0.141
I34 Nonrheumatic mitral valve disorders
0.000 0.860 0.140
I08.9 Multiple valve disease, unspecified
0.000 0.861 0.138
N81.3 Complete uterovaginal prolapse
0.000 0.861 0.139
I08.0 Disorders of both mitral and aortic valves
0.000 0.862 0.138
I49.5 Sick sinus syndrome
0.000 0.865 0.135
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.867 0.133
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.867 0.133
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.867 0.133
I98.0 Cardiovascular syphilis
0.000 0.867 0.133
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.001 0.869 0.130
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.001 0.869 0.130
I27 Other pulmonary heart diseases
0.000 0.869 0.130
I33.0 Acute and subacute infective endocarditis
0.001 0.870 0.130
I70.2 Atherosclerosis of arteries of the extremities
0.001 0.870 0.129
I05.2 Mitral stenosis with insufficiency
0.000 0.870 0.129
I70.11 Atherosclerosis of renal artery (with gangrene)
0.001 0.874 0.126
N81.2 Incomplete uterovaginal prolapse
0.000 0.876 0.124
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.878 0.122
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.880 0.120
I70.81 Atherosclerosis of other arteries (with gangrene)
0.001 0.882 0.118
I95 Hypotension
0.000 0.882 0.118
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.885 0.115
I28.1 Aneurysm of pulmonary artery
0.000 0.885 0.115
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.885 0.115
I27.2 Other secondary pulmonary hypertension
0.000 0.887 0.113
I26 Pulmonary embolism
0.000 0.888 0.112
I05.8 Other mitral valve diseases
0.000 0.888 0.111
I35 Nonrheumatic aortic valve disorders
0.000 0.889 0.110
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.890 0.110
I77.9 Disorder of arteries and arterioles, unspecified
0.001 0.890 0.109
I70.01 Atherosclerosis of aorta (with gangrene)
0.001 0.891 0.109
I06.1 Rheumatic aortic insufficiency
0.001 0.892 0.107
N81.9 Female genital prolapse, unspecified
0.000 0.893 0.107
I47.2 Ventricular tachycardia
0.000 0.895 0.105
I47.0 Reentry ventricular arrhythmia
0.000 0.897 0.103
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.900 0.100
I70.80 Atherosclerosis of other arteries (without gangrene)
0.001 0.900 0.100
I28.8 Other specified diseases of pulmonary vessels
0.000 0.902 0.098
I49.9 Cardiac arrhythmia, unspecified
0.000 0.902 0.097
I73.8 Other specified peripheral vascular diseases
0.000 0.903 0.097
I34.1 Mitral (valve) prolapse
0.000 0.904 0.096
I27.1 Kyphoscoliotic heart disease
0.000 0.906 0.094
I05.0 Mitral stenosis
0.000 0.907 0.092
N81.0 Female urethrocele
0.000 0.909 0.091
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.001 0.909 0.090
N81.6 Rectocele
0.000 0.910 0.090
I95.2 Hypotension due to drugs
0.000 0.910 0.090
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.914 0.086
I95.0 Idiopathic hypotension
0.000 0.915 0.085
I35.8 Other aortic valve disorders
0.000 0.915 0.085
I95.8 Other hypotension
0.000 0.916 0.084
I27.8 Other specified pulmonary heart diseases
0.000 0.917 0.083
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.919 0.081
I70.00 Atherosclerosis of aorta (without gangrene)
0.001 0.921 0.078
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.922 0.078
I05.1 Rheumatic mitral insufficiency
0.001 0.923 0.077
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.923 0.076
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.927 0.073
I50 Heart failure
0.000 0.929 0.071
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.932 0.068
I05.9 Mitral valve disease, unspecified
0.001 0.934 0.065
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.934 0.065
I73.9 Peripheral vascular disease, unspecified
0.000 0.934 0.066
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.935 0.065
I27.0 Primary pulmonary hypertension
0.000 0.936 0.064
I95.1 Orthostatic hypotension
0.000 0.938 0.062
I89.0 Lymphoedema, not elsewhere classified
0.000 0.938 0.061
I45.1 Other and unspecified right bundle-branch block
0.000 0.942 0.058
I27.9 Pulmonary heart disease, unspecified
0.000 0.942 0.057
I86 Varicose veins of other sites
0.000 0.945 0.055
I88 Nonspecific lymphadenitis
0.000 0.947 0.053
I86.1 Scrotal varices
0.000 0.948 0.052
I89.1 Lymphangitis
0.000 0.949 0.050
I78.1 Naevus, nonneoplastic
0.001 0.950 0.049
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.950 0.050
I80 Phlebitis and thrombophlebitis
0.000 0.951 0.049
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.952 0.048
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.001 0.953 0.046
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.957 0.043
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.958 0.042
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.958 0.042
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.959 0.041
I86.3 Vulval varices
0.000 0.960 0.040
I86.2 Pelvic varices
0.000 0.960 0.040
I86.0 Sublingual varices
0.000 0.960 0.040
I88.8 Other nonspecific lymphadenitis
0.000 0.962 0.038
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.962 0.038
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.962 0.038
I34.0 Mitral (valve) insufficiency
0.000 0.964 0.036
I73.0 Raynaud's syndrome
0.000 0.965 0.035
I35.1 Aortic (valve) insufficiency
0.000 0.966 0.034
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.966 0.034
I35.9 Aortic valve disorder, unspecified
0.001 0.967 0.032
C15.5 Lower third of oesophagus
0.033 0.967 0.000
I60-I69 Cerebrovascular diseases
0.000 0.968 0.032
I62 Other nontraumatic intracranial haemorrhage
0.000 0.969 0.031
I82 Other venous embolism and thrombosis
0.000 0.969 0.030
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.969 0.031
I47.1 Supraventricular tachycardia
0.000 0.970 0.030
I86.4 Gastric varices
0.000 0.970 0.030
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.970 0.030
I86.8 Varicose veins of other specified sites
0.000 0.970 0.030
I87 Other disorders of veins
0.000 0.971 0.029
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.971 0.028
C15 Malignant neoplasm of oesophagus
0.025 0.975 0.000
N81.4 Uterovaginal prolapse, unspecified
0.000 0.975 0.025
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.975 0.025
I85 Oesophageal varices
0.000 0.976 0.024
I51.7 Cardiomegaly
0.000 0.976 0.024
C15.9 Oesophagus, unspecified
0.024 0.976 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.977 0.023
I62.1 Nontraumatic extradural haemorrhage
0.000 0.977 0.022
I81 Portal vein thrombosis
0.001 0.977 0.022
I82.8 Embolism and thrombosis of other specified veins
0.000 0.978 0.022
I82.3 Embolism and thrombosis of renal vein
0.000 0.978 0.022
I82.1 Thrombophlebitis migrans
0.000 0.978 0.022
I82.0 Budd-Chiari syndrome
0.000 0.978 0.022
I35.0 Aortic (valve) stenosis
0.000 0.978 0.022
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.978 0.022
C15.4 Middle third of oesophagus
0.022 0.978 0.000
I87.9 Disorder of vein, unspecified
0.000 0.979 0.021
I87.0 Postphlebitic syndrome
0.000 0.979 0.021
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.979 0.020
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.980 0.020
I50.9 Heart failure, unspecified
0.000 0.981 0.019
C15.8 Overlapping lesion of oesophagus
0.018 0.982 0.000
C15.2 Abdominal part of oesophagus
0.018 0.982 0.000
C15.1 Thoracic part of oesophagus
0.018 0.982 0.000
C15.0 Cervical part of oesophagus
0.018 0.982 0.000
C15.3 Upper third of oesophagus
0.017 0.982 0.000
I60 Subarachnoid haemorrhage
0.000 0.983 0.017
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.983 0.017
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.983 0.017
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.983 0.017
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.983 0.017
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.983 0.017
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.983 0.017
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.983 0.017
I50.0 Congestive heart failure
0.000 0.984 0.016
I50.1 Left ventricular failure
0.000 0.984 0.016
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.984 0.016
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.984 0.016
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.984 0.016
I83 Varicose veins of lower extremities
0.000 0.984 0.016
I82.2 Embolism and thrombosis of vena cava
0.001 0.984 0.015
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.985 0.015
I68.0 Cerebral amyloid angiopathy
0.000 0.985 0.015
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.985 0.014
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.985 0.014
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.985 0.014
I65.1 Occlusion and stenosis of basilar artery
0.000 0.985 0.014
I87.1 Compression of vein
0.000 0.985 0.014
I69 Sequelae of cerebrovascular disease
0.000 0.986 0.014
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.986 0.014
I87.8 Other specified disorders of veins
0.000 0.986 0.013
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.986 0.013
I85.0 Oesophageal varices with bleeding
0.001 0.987 0.013
I65.2 Occlusion and stenosis of carotid artery
0.000 0.987 0.013
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.987 0.013
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.987 0.013
I95.9 Hypotension, unspecified
0.000 0.987 0.013
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.987 0.012
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.987 0.012
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.988 0.012
C09.9 Tonsil, unspecified
0.012 0.988 0.000
M86.9 Osteomyelitis, unspecified
0.012 0.988 0.000
I60.8 Other subarachnoid haemorrhage
0.000 0.988 0.012
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.988 0.012
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.989 0.011
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.989 0.011
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.011 0.989 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.989 0.011
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.989 0.011
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.989 0.010
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.989 0.010
M86 Osteomyelitis
0.010 0.990 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.010 0.990 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.990 0.010
M86.94 Osteomyelitis, unspecified (Hand)
0.010 0.990 0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.010 0.990 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.010 0.990 0.000
M86.98 Osteomyelitis, unspecified (Other)
0.009 0.990 0.000
I63 Cerebral infarction
0.000 0.990 0.010
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.000 0.991 0.009
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.991 0.009
M86.93 Osteomyelitis, unspecified (Forearm)
0.009 0.991 0.000
M86.92 Osteomyelitis, unspecified (Upper arm)
0.009 0.991 0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.009 0.991 0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.009 0.991 0.000
C09 Malignant neoplasm of tonsil
0.009 0.991 0.000
M89.0 Algoneurodystrophy
0.009 0.991 0.000
I61 Intracerebral haemorrhage
0.000 0.992 0.008
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.008 0.992 0.000
M89 Other disorders of bone
0.008 0.992 0.000
M86-M90 Other osteopathies
0.008 0.992 0.000
M86.6 Other chronic osteomyelitis
0.008 0.992 0.000
M86.8 Other osteomyelitis
0.008 0.992 0.000
M89.09 Algoneurodystrophy (Site unspecified)
0.008 0.992 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.992 0.008
I69.3 Sequelae of cerebral infarction
0.000 0.992 0.008
M89.8 Other specified disorders of bone
0.008 0.992 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.007 0.992 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.007 0.992 0.000
M86.3 Chronic multifocal osteomyelitis
0.007 0.992 0.000
M86.2 Subacute osteomyelitis
0.007 0.992 0.000
M86.1 Other acute osteomyelitis
0.007 0.992 0.000
M86.0 Acute haematogenous osteomyelitis
0.007 0.992 0.000
I63.8 Other cerebral infarction
0.000 0.993 0.007
M89.00 Algoneurodystrophy (Multiple sites)
0.007 0.993 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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