TreeWAS – Variant ID: rs17422727

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E10.9 Without complications	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.000	1.000
E10-E14 Diabetes mellitus	0.000	0.000	1.000
E10.3 With ophthalmic complications	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.001	0.999
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.001	0.999
G35 Multiple sclerosis	0.000	0.002	0.998
D50 Iron deficiency anaemia	0.000	0.002	0.998
D50-D53 Nutritional anaemias	0.000	0.003	0.997
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.010	0.990
E05.9 Thyrotoxicosis, unspecified	0.000	0.011	0.989
E10.1 With ketoacidosis	0.000	0.011	0.989
D50.8 Other iron deficiency anaemias	0.000	0.014	0.986
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.015	0.985
D80-D89 Certain disorders involving the immune mechanism	0.000	0.020	0.980
D86 Sarcoidosis	0.000	0.021	0.979
D50.9 Iron deficiency anaemia, unspecified	0.000	0.021	0.979
L40 Psoriasis	0.000	0.023	0.977
E27 Other disorders of adrenal gland	0.000	0.025	0.975
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.026	0.974
E20-E35 Disorders of other endocrine glands	0.000	0.026	0.974
D86.9 Sarcoidosis, unspecified	0.000	0.029	0.971
E27.1 Primary adrenocortical insufficiency	0.000	0.031	0.969
E50-E64 Other nutritional deficiencies	0.000	0.062	0.938
D51 Vitamin B12 deficiency anaemia	0.000	0.069	0.931
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.071	0.929
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.072	0.928
H36.0 Diabetic retinopathy	0.000	0.082	0.918
L40-L45 Papulosquamous disorders	0.000	0.085	0.915
H36 Retinal disorders in diseases classified elsewhere	0.000	0.087	0.913
Chapter VII Diseases of the eye and adnexa	0.000	0.088	0.912
# Top node	0.000	0.089	0.911
H30-H36 Disorders of choroid and retina	0.000	0.090	0.910
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	0.096	0.904
L40.0 Psoriasis vulgaris	0.000	0.100	0.900
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.104	0.896
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.108	0.892
Chapter VI Diseases of the nervous system	0.000	0.109	0.891
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.112	0.888
E14 Unspecified diabetes mellitus	0.000	0.115	0.885
E10.5 With peripheral circulatory complications	0.000	0.116	0.884
D86.1 Sarcoidosis of lymph nodes	0.000	0.116	0.884
E70-E90 Metabolic disorders	0.000	0.117	0.883
E86 Volume depletion	0.000	0.124	0.876
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.000	0.132	0.868
E07 Other disorders of thyroid	0.000	0.133	0.867
E55 Vitamin D deficiency	0.000	0.136	0.864
H46-H48 Disorders of optic nerve and visual pathways	0.000	0.141	0.859
H02 Other disorders of eyelid	0.000	0.143	0.857
E53 Deficiency of other B group vitamins	0.000	0.152	0.847
H02.1 Ectropion of eyelid	0.000	0.153	0.847
E06 Thyroiditis	0.000	0.157	0.843
D68 Other coagulation defects	0.000	0.157	0.843
E14.3 With ophthalmic complications	0.000	0.163	0.837
E10.2 With renal complications	0.000	0.164	0.836
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.000	0.165	0.835
E10.0 With coma	0.000	0.170	0.830
D52 Folate deficiency anaemia	0.000	0.170	0.830
E16 Other disorders of pancreatic internal secretion	0.000	0.179	0.821
D86.0 Sarcoidosis of lung	0.000	0.183	0.817
H33 Retinal detachments and breaks	0.000	0.186	0.814
E55.9 Vitamin D deficiency, unspecified	0.000	0.188	0.812
L40.8 Other psoriasis	0.000	0.189	0.811
H46 Optic neuritis	0.000	0.191	0.809
D86.8 Sarcoidosis of other and combined sites	0.000	0.193	0.807
H20 Iridocyclitis	0.000	0.199	0.801
E27.8 Other specified disorders of adrenal gland	0.000	0.220	0.780
E53.8 Deficiency of other specified B group vitamins	0.000	0.223	0.777
E16.2 Hypoglycaemia, unspecified	0.000	0.229	0.771
L20-L30 Dermatitis and eczema	0.000	0.230	0.770
E27.9 Disorder of adrenal gland, unspecified	0.000	0.236	0.764
H33.3 Retinal breaks without detachment	0.000	0.236	0.764
E27.2 Addisonian crisis	0.000	0.239	0.761
H20.0 Acute and subacute iridocyclitis	0.000	0.240	0.760
E10.4 With neurological complications	0.000	0.243	0.757
E88 Other metabolic disorders	0.000	0.249	0.751
G90-G99 Other disorders of the nervous system	0.000	0.250	0.750
D68.0 Von Willebrand's disease	0.000	0.250	0.749
E07.8 Other specified disorders of thyroid	0.000	0.253	0.747
D53 Other nutritional anaemias	0.000	0.255	0.745
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.265	0.735
L10-L14 Bullous disorders	0.000	0.269	0.731
E06.3 Autoimmune thyroiditis	0.000	0.270	0.730
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.272	0.728
H16 Keratitis	0.000	0.272	0.728
H02.5 Other disorders affecting eyelid function	0.000	0.275	0.725
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.276	0.724
E20 Hypoparathyroidism	0.000	0.281	0.718
E10.7 With multiple complications	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.717	0.283	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.284	0.716
E05.5 Thyroid crisis or storm	0.000	0.284	0.716
E05.4 Thyrotoxicosis factitia	0.000	0.284	0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.284	0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.284	0.716
H02.9 Disorder of eyelid, unspecified	0.000	0.284	0.716
D50.1 Sideropenic dysphagia	0.000	0.284	0.715
H33.2 Serous retinal detachment	0.000	0.285	0.715
D68.8 Other specified coagulation defects	0.000	0.287	0.713
E73 Lactose intolerance	0.000	0.289	0.711
D52.9 Folate deficiency anaemia, unspecified	0.000	0.290	0.710
E10.6 With other specified complications	0.000	0.292	0.708
G30-G32 Other degenerative diseases of the nervous system	0.000	0.293	0.707
H20.9 Iridocyclitis, unspecified	0.000	0.297	0.703
D82 Immunodeficiency associated with other major defects	0.000	0.297	0.703
D81 Combined immunodeficiencies	0.000	0.297	0.703
D86.3 Sarcoidosis of skin	0.000	0.298	0.702
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.298	0.702
H33.4 Traction detachment of retina	0.000	0.298	0.702
L40.3 Pustulosis palmaris et plantaris	0.000	0.300	0.700
L40.2 Acrodermatitis continua	0.000	0.300	0.700
L40.1 Generalised pustular psoriasis	0.000	0.300	0.700
G91 Hydrocephalus	0.000	0.300	0.700
E27.5 Adrenomedullary hyperfunction	0.000	0.301	0.699
E27.0 Other adrenocortical overactivity	0.000	0.301	0.699
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.302	0.698
E32 Diseases of thymus	0.000	0.302	0.698
E31 Polyglandular dysfunction	0.000	0.302	0.698
E30 Disorders of puberty, not elsewhere classified	0.000	0.302	0.698
D68.2 Hereditary deficiency of other clotting factors	0.000	0.302	0.698
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.304	0.696
H53-H54 Visual disturbances and blindness	0.000	0.305	0.695
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.307	0.693
H16.0 Corneal ulcer	0.000	0.318	0.682
D66 Hereditary factor VIII deficiency	0.000	0.326	0.674
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.328	0.672
E63 Other nutritional deficiencies	0.000	0.328	0.672
E56 Other vitamin deficiencies	0.000	0.328	0.672
E51 Thiamine deficiency	0.000	0.328	0.672
E50 Vitamin A deficiency	0.000	0.328	0.672
E60 Dietary zinc deficiency	0.000	0.328	0.672
E59 Dietary selenium deficiency	0.000	0.328	0.672
E54 Ascorbic acid deficiency	0.000	0.328	0.672
E52 Niacin deficiency [pellagra]	0.000	0.328	0.672
E07.9 Disorder of thyroid, unspecified	0.000	0.328	0.672
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.332	0.668
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.333	0.667
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.333	0.667
D51.2 Transcobalamin II deficiency	0.000	0.333	0.667
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.333	0.667
G36 Other acute disseminated demyelination	0.000	0.334	0.666
E85 Amyloidosis	0.000	0.335	0.665
E24 Cushing's syndrome	0.000	0.335	0.665
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.336	0.664
D68.5 Primary Thrombophilia	0.000	0.338	0.662
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.340	0.660
D55-D59 Haemolytic anaemias	0.000	0.341	0.659
H05 Disorders of orbit	0.000	0.341	0.659
L44 Other papulosquamous disorders	0.000	0.344	0.656
L41 Parapsoriasis	0.000	0.344	0.656
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.344	0.656
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.345	0.655
E25 Adrenogenital disorders	0.000	0.346	0.654
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.347	0.653
Chapter XVI Certain conditions originating in the perinatal period	0.000	0.347	0.653
H32 Chorioretinal disorders in diseases classified elsewhere	0.000	0.347	0.652
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.350	0.650
H02.8 Other specified disorders of eyelid	0.000	0.350	0.650
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.350	0.650
E78.2 Mixed hyperlipidaemia	0.000	0.351	0.649
H00 Hordeolum and chalazion	0.000	0.355	0.645
E15 Nondiabetic hypoglycaemic coma	0.000	0.358	0.642
H02.2 Lagophthalmos	0.000	0.359	0.641
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.000	0.359	0.641
E74 Other disorders of carbohydrate metabolism	0.000	0.359	0.640
E10.8 With unspecified complications	0.000	0.361	0.639
D67 Hereditary factor IX deficiency	0.000	0.363	0.637
E78.4 Other hyperlipidaemia	0.000	0.364	0.635
E14.7 With multiple complications	0.000	0.366	0.634
E14.6 With other specified complications	0.000	0.366	0.634
E14.1 With ketoacidosis	0.000	0.366	0.634
E14.0 With coma	0.000	0.366	0.634
L40.4 Guttate psoriasis	0.000	0.367	0.633
E79 Disorders of purine and pyrimidine metabolism	0.000	0.367	0.633
E77 Disorders of glycoprotein metabolism	0.000	0.367	0.633
E76 Disorders of glycosaminoglycan metabolism	0.000	0.367	0.633
E72 Other disorders of amino-acid metabolism	0.000	0.367	0.633
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.367	0.633
E70 Disorders of aromatic amino-acid metabolism	0.000	0.367	0.633
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.367	0.633
L40.5 Arthropathic psoriasis	0.000	0.369	0.631
E14.8 With unspecified complications	0.000	0.370	0.630
L27 Dermatitis due to substances taken internally	0.000	0.370	0.630
E05.8 Other thyrotoxicosis	0.000	0.370	0.629
E53.9 Vitamin B deficiency, unspecified	0.000	0.373	0.627
E28 Ovarian dysfunction	0.000	0.374	0.626
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.000	0.374	0.626
G91.9 Hydrocephalus, unspecified	0.000	0.374	0.626
E29 Testicular dysfunction	0.000	0.374	0.625
L21 Seborrhoeic dermatitis	0.000	0.376	0.624
E07.1 Dyshormogenetic goitre	0.000	0.378	0.621
E07.0 Hypersecretion of calcitonin	0.000	0.378	0.621
E55.0 Rickets, active	0.000	0.380	0.620
E14.9 Without complications	0.000	0.380	0.620
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.000	0.383	0.616
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.000	0.384	0.616
E78.8 Other disorders of lipoprotein metabolism	0.000	0.384	0.616
D83 Common variable immunodeficiency	0.000	0.385	0.615
H02.7 Other degenerative disorders of eyelid and periocular area	0.000	0.385	0.614
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.388	0.612
H10-H13 Disorders of conjunctiva	0.000	0.389	0.611
E03.8 Other specified hypothyroidism	0.000	0.389	0.610
H30 Chorioretinal inflammation	0.000	0.390	0.610
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.610	0.390	0.000
E14.2 Withrenal complications	0.000	0.392	0.608
E53.1 Pyridoxine deficiency	0.000	0.392	0.608
E53.0 Riboflavin deficiency	0.000	0.392	0.608
E58 Dietary calcium deficiency	0.000	0.393	0.607
H34 Retinal vascular occlusions	0.000	0.393	0.607
E06.9 Thyroiditis, unspecified	0.000	0.393	0.607
E11 Non-insulin-dependent diabetes mellitus	0.000	0.394	0.606
G31.8 Other specified degenerative diseases of nervous system	0.000	0.394	0.605
E06.5 Other chronic thyroiditis	0.000	0.395	0.604
E06.4 Drug-induced thyroiditis	0.000	0.395	0.604
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.395	0.604
E06.1 Subacute thyroiditis	0.000	0.395	0.604
E06.0 Acute thyroiditis	0.000	0.395	0.604
D68.4 Acquired coagulation factor deficiency	0.000	0.396	0.604
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.397	0.603
H02.6 Xanthelasma of eyelid	0.000	0.397	0.603
G20-G26 Extrapyramidal and movement disorders	0.000	0.398	0.602
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.398	0.602
E84 Cystic fibrosis	0.000	0.403	0.597
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.404	0.596
D52.8 Other folate deficiency anaemias	0.000	0.405	0.595
D52.1 Drug-induced folate deficiency anaemia	0.000	0.405	0.595
D52.0 Dietary folate deficiency anaemia	0.000	0.405	0.595
G37 Other demyelinating diseases of central nervous system	0.000	0.406	0.594
E14.4 With neurological complications	0.000	0.408	0.592
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.409	0.591
G91.1 Obstructive hydrocephalus	0.000	0.411	0.589
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.411	0.589
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.411	0.589
E16.4 Abnormal secretion of gastrin	0.000	0.411	0.589
E16.3 Increased secretion of glucagon	0.000	0.411	0.589
D84 Other immunodeficiencies	0.000	0.411	0.588
E73.9 Lactose intolerance, unspecified	0.000	0.412	0.588
L28 Lichen simplex chronicus and prurigo	0.000	0.414	0.586
H05.0 Acute inflammation of orbit	0.000	0.414	0.586
H18 Other disorders of cornea	0.000	0.420	0.580
E88.2 Lipomatosis, not elsewhere classified	0.000	0.420	0.580
L13 Other bullous disorders	0.000	0.420	0.580
L25 Unspecified contact dermatitis	0.000	0.420	0.580
G90 Disorders of autonomic nervous system	0.000	0.421	0.579
L20 Atopic dermatitis	0.000	0.423	0.577
H20.2 Lens-induced iridocyclitis	0.000	0.425	0.574
H20.1 Chronic iridocyclitis	0.000	0.425	0.574
Chapter I Certain infectious and parasitic diseases	0.000	0.426	0.574
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.426	0.574
E14.5 With peripheral circulatory complications	0.000	0.427	0.573
D68.1 Hereditary factor XI deficiency	0.000	0.430	0.570
H02.4 Ptosis of eyelid	0.000	0.431	0.569
L23 Allergic contact dermatitis	0.000	0.434	0.566
D68.6 Other Thrombophilia	0.000	0.434	0.565
D53.9 Nutritional anaemia, unspecified	0.000	0.435	0.565
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.000	0.437	0.563
E34 Other endocrine disorders	0.000	0.442	0.558
E16.1 Other hypoglycaemia	0.000	0.443	0.557
E61 Deficiency of other nutrient elements	0.000	0.444	0.556
L11 Other acantholytic disorders	0.000	0.444	0.556
E40-E46 Malnutrition	0.000	0.444	0.556
L24 Irritant contact dermatitis	0.000	0.448	0.552
L26 Exfoliative dermatitis	0.000	0.448	0.552
L22 Diaper [napkin] dermatitis	0.000	0.448	0.552
E22 Hyperfunction of pituitary gland	0.000	0.448	0.552
L29 Pruritus	0.000	0.448	0.552
H03 Disorders of eyelid in diseases classified elsewhere	0.000	0.453	0.546
D59 Acquired haemolytic anaemia	0.000	0.454	0.546
H33.1 Retinoschisis and retinal cysts	0.000	0.454	0.546
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.455	0.544
E04 Other non-toxic goitre	0.000	0.456	0.544
H01 Other inflammation of eyelid	0.000	0.458	0.542
G91.0 Communicating hydrocephalus	0.000	0.459	0.541
A50-A64 Infections with a predominantly sexual mode of transmission	0.000	0.460	0.540
E88.8 Other specified metabolic disorders	0.000	0.461	0.539
E88.3 Tumour lysis syndrome	0.000	0.461	0.539
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.461	0.539
G98 Other disorders of nervous system, not elsewhere classified	0.000	0.462	0.538
G92 Toxic encephalopathy	0.000	0.462	0.538
E11.1 With ketoacidosis	0.000	0.464	0.536
E20.9 Hypoparathyroidism, unspecified	0.000	0.464	0.536
H47.2 Optic atrophy	0.000	0.464	0.536
D53.8 Other specified nutritional anaemias	0.000	0.466	0.534
D53.2 Scorbutic anaemia	0.000	0.466	0.534
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.466	0.534
D53.0 Protein deficiency anaemia	0.000	0.466	0.534
L12 Pemphigoid	0.000	0.469	0.531
H49 Paralytic strabismus	0.000	0.469	0.531
H15 Disorders of sclera	0.000	0.469	0.530
H54 Blindness and low vision	0.000	0.470	0.530
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.471	0.529
H16.1 Other superficial keratitis without conjunctivitis	0.000	0.472	0.528
L42 Pityriasis rosea	0.000	0.472	0.527
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.473	0.527
H17 Corneal scars and opacities	0.000	0.473	0.526
H50 Other strabismus	0.000	0.473	0.527
C82.0 Small cleaved cell, follicular	0.526	0.473	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.475	0.525
L10 Pemphigus	0.000	0.476	0.524
L14 Bullous disorders in diseases classified elsewhere	0.000	0.476	0.524
H47.3 Other disorders of optic disk	0.000	0.476	0.524
C82.1 Mixed small cleaved and large cell, follicular	0.523	0.477	0.000
E78.6 Lipoprotein deficiency	0.000	0.478	0.522
E78.3 Hyperchylomicronaemia	0.000	0.478	0.522
H16.8 Other keratitis	0.000	0.478	0.522
H16.4 Corneal neovascularisation	0.000	0.478	0.522
H16.3 Interstitial and deep keratitis	0.000	0.478	0.522
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.479	0.521
E13 Other specified diabetes mellitus	0.001	0.479	0.520
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.480	0.520
C82.3 Follicular lymphoma grade IIIa	0.520	0.480	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.000	0.480	0.520
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.000	0.482	0.518
E85.9 Amyloidosis, unspecified	0.000	0.482	0.518
E26 Hyperaldosteronism	0.001	0.483	0.516
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.000	0.484	0.515
E20.8 Other hypoparathyroidism	0.000	0.485	0.515
E20.1 Pseudohypoparathyroidism	0.000	0.485	0.515
E20.0 Idiopathic hypoparathyroidism	0.000	0.485	0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E12.9 Without complications	0.000	0.486	0.514
E12.8 With unspecified complications	0.000	0.486	0.514
E12.7 With multiple complications	0.000	0.486	0.514
E12.6 With other specified complications	0.000	0.486	0.514
E12.5 With peripheral circulatory complications	0.000	0.486	0.514
E12.4 With neurological complications	0.000	0.486	0.514
E12.3 With ophthalmic complications	0.000	0.486	0.514
E12.2 With renal complications	0.000	0.486	0.514
E12.1 With ketoacidosis	0.000	0.486	0.514
E12.0 With coma	0.000	0.486	0.514
E11.3 With ophthalmic complications	0.000	0.488	0.512
E73.8 Other lactose intolerance	0.000	0.490	0.510
E73.1 Secondary lactase deficiency	0.000	0.490	0.510
E73.0 Congenital lactase deficiency	0.000	0.490	0.510
H53 Visual disturbances	0.000	0.491	0.509
H02.0 Entropion and trichiasis of eyelid	0.000	0.491	0.509
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.493	0.507
L50-L54 Urticaria and erythema	0.000	0.494	0.506
H18.6 Keratoconus	0.000	0.495	0.505
G93 Other disorders of brain	0.000	0.495	0.505
D81.9 Combined immunodeficiency, unspecified	0.000	0.496	0.504
D81.8 Other combined immunodeficiencies	0.000	0.496	0.504
D81.7 Major histocompatibility complex class II deficiency	0.000	0.496	0.504
D81.6 Major histocompatibility complex class I deficiency	0.000	0.496	0.504
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.496	0.504
D81.4 Nezelof's syndrome	0.000	0.496	0.504
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.496	0.504
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.496	0.504
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.496	0.504
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.496	0.504
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.496	0.504
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.496	0.504
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.496	0.504
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.496	0.504
D82.2 Immunodeficiency with short-limbed stature	0.000	0.496	0.504
D82.1 Di George's syndrome	0.000	0.496	0.504
D82.0 Wiskott-Aldrich syndrome	0.000	0.496	0.504
G91.8 Other hydrocephalus	0.000	0.498	0.502
G91.3 Posttraumatic hydrocephalus, unspecified	0.000	0.498	0.502
E30.9 Disorder of puberty, unspecified	0.000	0.499	0.500
E30.8 Other disorders of puberty	0.000	0.499	0.500
E30.1 Precocious puberty	0.000	0.499	0.500
E30.0 Delayed puberty	0.000	0.499	0.500
E31.9 Polyglandular dysfunction, unspecified	0.000	0.499	0.500
E31.8 Other polyglandular dysfunction	0.000	0.499	0.500
E31.1 Polyglandular hyperfunction	0.000	0.499	0.500
E31.0 Autoimmune polyglandular failure	0.000	0.499	0.500
E32.9 Disease of thymus, unspecified	0.000	0.499	0.500
E32.8 Other diseases of thymus	0.000	0.499	0.500
E32.1 Abscess of thymus	0.000	0.499	0.500
E32.0 Persistent hyperplasia of thymus	0.000	0.499	0.500
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.499	0.500
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.499	0.500
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.499	0.500
A63.0 Anogenital (venereal) warts	0.000	0.501	0.499
E85.4 Organ-limited amyloidosis	0.000	0.502	0.498
L80-L99 Other disorders of the skin and subcutaneous tissue	0.000	0.503	0.497
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.503	0.497
E65-E68 Obesity and other hyperalimentation	0.000	0.504	0.495
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.000	0.505	0.495
E11.4 With neurological complications	0.000	0.509	0.491
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.511	0.489
G91.2 Normal-pressure hydrocephalus	0.000	0.511	0.489
H20.8 Other iridocyclitis	0.000	0.512	0.488
E23 Hypofunction and other disorders of pituitary gland	0.000	0.513	0.487
E11.2 With renal complications	0.000	0.514	0.486
E50.9 Vitamin A deficiency, unspecified	0.000	0.518	0.482
E50.8 Other manifestations of vitamin A deficiency	0.000	0.518	0.482
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.518	0.482
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.518	0.482
E50.5 Vitamin A deficiency with night blindness	0.000	0.518	0.482
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.518	0.482
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.518	0.482
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.518	0.482
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.518	0.482
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.518	0.482
E51.9 Thiamine deficiency, unspecified	0.000	0.518	0.482
E51.8 Other manifestations of thiamine deficiency	0.000	0.518	0.482
E51.2 Wernicke's encephalopathy	0.000	0.518	0.482
E51.1 Beriberi	0.000	0.518	0.482
E56.9 Vitamin deficiency, unspecified	0.000	0.518	0.482
E56.8 Deficiency of other vitamins	0.000	0.518	0.482
E56.1 Deficiency of vitamin K	0.000	0.518	0.482
E56.0 Deficiency of vitamin E	0.000	0.518	0.482
E63.9 Nutritional deficiency, unspecified	0.000	0.518	0.482
E63.8 Other specified nutritional deficiencies	0.000	0.518	0.482
E63.1 Imbalance of constituents of food intake	0.000	0.518	0.482
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.518	0.482
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.518	0.482
E64.8 Sequelae of other nutritional deficiencies	0.000	0.518	0.482
E64.3 Sequelae of rickets	0.000	0.518	0.482
E64.2 Sequelae of vitamin C deficiency	0.000	0.518	0.482
E64.1 Sequelae of vitamin A deficiency	0.000	0.518	0.482
E64.0 Sequelae of protein-energy malnutrition	0.000	0.518	0.482
G63.2 Diabetic polyneuropathy	0.000	0.518	0.482
E88.9 Metabolic disorder, unspecified	0.000	0.520	0.480
H47.7 Disorder of visual pathways, unspecified	0.000	0.521	0.479
H47.6 Disorders of visual cortex	0.000	0.521	0.479
H47.5 Disorders of other visual pathways	0.000	0.521	0.479
H47.4 Disorders of optic chiasm	0.000	0.521	0.479
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.522	0.478
G36.9 Acute disseminated demyelination, unspecified	0.000	0.522	0.478
G36.8 Other specified acute disseminated demyelination	0.000	0.522	0.478
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.522	0.478
G36.0 Neuromyelitis optica [Devic]	0.000	0.522	0.478
H06.2 Dysthyroid exophthalmos	0.000	0.522	0.478
E85.8 Other amyloidosis	0.000	0.523	0.477
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.523	0.477
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.523	0.477
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.523	0.477
E24.8 Other Cushing's syndrome	0.000	0.523	0.477
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.523	0.477
E24.3 Ectopic ACTH syndrome	0.000	0.523	0.477
E24.1 Nelson's syndrome	0.000	0.523	0.477
E24.0 Pituitary-dependent Cushing's disease	0.000	0.523	0.477
G20 Parkinson's disease	0.000	0.527	0.473
G97.8 Other postprocedural disorders of nervous system	0.000	0.527	0.473
D55 Anaemia due to enzyme disorders	0.000	0.527	0.472
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.000	0.527	0.472
H05.3 Deformity of orbit	0.000	0.527	0.472
H05.1 Chronic inflammatory disorders of orbit	0.000	0.527	0.472
H53.1 Subjective visual disturbances	0.000	0.528	0.472
L13.0 Dermatitis herpetiformis	0.000	0.528	0.471
L41.9 Parapsoriasis, unspecified	0.000	0.529	0.470
L41.8 Other parapsoriasis	0.000	0.529	0.470
L41.5 Retiform parapsoriasis	0.000	0.529	0.470
L41.4 Large plaque parapsoriasis	0.000	0.529	0.470
L41.3 Small plaque parapsoriasis	0.000	0.529	0.470
L41.2 Lymphomatoid papulosis	0.000	0.529	0.470
L41.1 Pityriasis lichenoides chronica	0.000	0.529	0.470
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.529	0.470
L44.9 Papulosquamous disorder, unspecified	0.000	0.529	0.470
L44.8 Other specified papulosquamous disorders	0.000	0.529	0.470
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.529	0.470
L44.3 Lichen ruber moniliformis	0.000	0.529	0.470
L44.2 Lichen striatus	0.000	0.529	0.470
L44.1 Lichen nitidus	0.000	0.529	0.470
L44.0 Pityriasis rubra pilaris	0.000	0.529	0.470
E25.9 Adrenogenital disorder, unspecified	0.000	0.531	0.469
E25.8 Other adrenogenital disorders	0.000	0.531	0.469
B07 Viral warts	0.000	0.531	0.469
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.531	0.468
P90-P96 Other disorders originating in the perinatal period	0.000	0.531	0.468
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.000	0.531	0.468
P75-P78 Digestive system disorders of fetus and newborn	0.000	0.531	0.468
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.000	0.531	0.468
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.000	0.531	0.468
P35-P39 Infections specific to the perinatal period	0.000	0.531	0.468
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.000	0.531	0.468
P10-P15 Birth trauma	0.000	0.531	0.468
P05-P08 Disorders related to length of gestation and fetal growth	0.000	0.531	0.468
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.000	0.531	0.468
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.000	0.532	0.468
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.000	0.532	0.468
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.532	0.468
D56 Thalassaemia	0.000	0.533	0.467
H21 Other disorders of iris and ciliary body	0.000	0.533	0.467
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.533	0.467
L27.2 Dermatitis due to ingested food	0.000	0.533	0.467
H16.2 Keratoconjunctivitis	0.000	0.533	0.466
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.534	0.466

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations