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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17443266
log Bayes Factor = 15.2354
Chromosome 12   position 19,169,453  (GRCh37) Explore rs17443266 on Ensembl!
Variant rs17443266 is part of Cluster X0082

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
0.999 0.001 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.996 0.004 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
D10-D36 Benign neoplasms
0.995 0.005 0.000
C78.7 Secondary malignant neoplasm of liver
0.994 0.006 0.000
N10-N16 Renal tubulo-interstitial diseases
0.992 0.008 0.000
D17 Benign lipomatous neoplasm
0.991 0.009 0.000
N13 Obstructive and reflux uropathy
0.987 0.013 0.000
E70-E90 Metabolic disorders
0.985 0.015 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.983 0.017 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.982 0.018 0.000
Chapter VI Diseases of the nervous system
0.981 0.019 0.000
C18 Malignant neoplasm of colon
0.973 0.027 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.971 0.029 0.000
H43-H45 Disorders of vitreous body and globe
0.968 0.032 0.000
Chapter XXI Factors influencing health status and contact with health services
0.968 0.032 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.965 0.035 0.000
N20-N23 Urolithiasis
0.962 0.038 0.000
H25-H28 Disorders of lens
0.961 0.039 0.000
Z50 Care involving use of rehabilitation procedures
0.957 0.043 0.000
C51-C58 Malignant neoplasms of female genital organs
0.953 0.047 0.000
H43 Disorders of vitreous body
0.945 0.055 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.944 0.056 0.000
H30-H36 Disorders of choroid and retina
0.938 0.062 0.000
C78.0 Secondary malignant neoplasm of lung
0.933 0.067 0.000
G40-G47 Episodic and paroxysmal disorders
0.929 0.071 0.000
O48 Prolonged pregnancy
0.927 0.073 0.000
Z43 Attention to artificial openings
0.925 0.075 0.000
H53-H54 Visual disturbances and blindness
0.916 0.084 0.000
H25 Senile cataract
0.916 0.084 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.915 0.085 0.000
C18.7 Sigmoid colon
0.911 0.089 0.000
C16 Malignant neoplasm of stomach
0.909 0.091 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.907 0.092 0.000
H02 Other disorders of eyelid
0.907 0.093 0.000
O42 Premature rupture of membranes
0.906 0.094 0.000
N13.3 Other and unspecified hydronephrosis
0.905 0.095 0.000
H43.8 Other disorders of vitreous body
0.903 0.097 0.000
Z50.1 Other physical therapy
0.902 0.098 0.000
E20-E35 Disorders of other endocrine glands
0.901 0.099 0.000
G47 Sleep disorders
0.899 0.101 0.000
H25.1 Senile nuclear cataract
0.898 0.102 0.000
E10-E14 Diabetes mellitus
0.893 0.107 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.892 0.108 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.892 0.108 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.892 0.108 0.000
N23 Unspecified renal colic
0.891 0.109 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.889 0.111 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.888 0.112 0.000
C15 Malignant neoplasm of oesophagus
0.887 0.113 0.000
H33 Retinal detachments and breaks
0.886 0.114 0.000
Chapter I Certain infectious and parasitic diseases
0.883 0.117 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.883 0.117 0.000
G47.3 Sleep apnoea
0.883 0.117 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.882 0.118 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.879 0.121 0.000
D23 Other benign neoplasms of skin
0.877 0.123 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.875 0.125 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.874 0.126 0.000
N60-N64 Disorders of breast
0.871 0.129 0.000
O60-O75 Complications of labour and delivery
0.867 0.133 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.865 0.135 0.000
C25 Malignant neoplasm of pancreas
0.865 0.135 0.000
R19.4 Change in bowel habit
0.860 0.140 0.000
O80-O84 Delivery
0.860 0.140 0.000
D00-D09 In situ neoplasms
0.859 0.141 0.000
C54 Malignant neoplasm of corpus uteri
0.858 0.142 0.000
E87.0 Hyperosmolality and hypernatraemia
0.853 0.147 0.000
E89.0 Postprocedural hypothyroidism
0.852 0.148 0.000
Z50.5 Speech therapy
0.849 0.151 0.000
Z43.3 Attention to colostomy
0.849 0.151 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.848 0.152 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.848 0.152 0.000
O36 Maternal care for other known or suspected foetal problems
0.847 0.153 0.000
E87.5 Hyperkalaemia
0.846 0.154 0.000
H53 Visual disturbances
0.844 0.156 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.844 0.156 0.000
H43.3 Other vitreous opacities
0.842 0.158 0.000
H36 Retinal disorders in diseases classified elsewhere
0.841 0.159 0.000
Chapter XX External causes of morbidity and mortality
0.840 0.160 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.828 0.171 0.000
H33.3 Retinal breaks without detachment
0.828 0.172 0.000
H02.0 Entropion and trichiasis of eyelid
0.827 0.173 0.000
D24 Benign neoplasm of breast
0.825 0.175 0.000
N21 Calculus of lower urinary tract
0.824 0.176 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.822 0.178 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.820 0.180 0.000
R14 Flatulence and related conditions
0.818 0.182 0.000
G62 Other polyneuropathies
0.817 0.183 0.000
C17 Malignant neoplasm of small intestine
0.816 0.184 0.000
R17 Unspecified jaundice
0.815 0.185 0.000
H10-H13 Disorders of conjunctiva
0.814 0.186 0.000
D37.5 Rectum
0.810 0.190 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.809 0.191 0.000
C18.3 Hepatic flexure
0.808 0.192 0.000
H02.1 Ectropion of eyelid
0.807 0.193 0.000
B15-B19 Viral hepatitis
0.806 0.194 0.000
E87.2 Acidosis
0.805 0.195 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.804 0.196 0.000
C20 Malignant neoplasm of rectum
0.804 0.196 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.801 0.199 0.000
C16.0 Cardia
0.800 0.200 0.000
H55-H59 Other disorders of eye and adnexa
0.798 0.202 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.796 0.204 0.000
C18.9 Colon, unspecified
0.795 0.205 0.000
C15.9 Oesophagus, unspecified
0.795 0.205 0.000
Z45 Adjustment and management of implanted device
0.795 0.205 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.795 0.205 0.000
Z46 Fitting and adjustment of other devices
0.794 0.206 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.793 0.207 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.792 0.208 0.000
C54.1 Endometrium
0.790 0.210 0.000
N17-N19 Renal failure
0.790 0.210 0.000
D36 Benign neoplasm of other and unspecified sites
0.790 0.210 0.000
D23.5 Skin of trunk
0.789 0.211 0.000
N13.8 Other obstructive and reflux uropathy
0.788 0.212 0.000
E10 Insulin-dependent diabetes mellitus
0.786 0.214 0.000
Z49 Care involving dialysis
0.786 0.214 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.784 0.216 0.000
N00-N08 Glomerular diseases
0.780 0.220 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.780 0.220 0.000
E50-E64 Other nutritional deficiencies
0.778 0.222 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.777 0.223 0.000
N13.6 Pyonephrosis
0.775 0.225 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.775 0.225 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.774 0.226 0.000
N20 Calculus of kidney and ureter
0.774 0.226 0.000
O63 Long labour
0.773 0.227 0.000
C18.4 Transverse colon
0.771 0.228 0.000
G90-G99 Other disorders of the nervous system
0.771 0.229 0.000
H36.0 Diabetic retinopathy
0.771 0.229 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.769 0.231 0.000
E87.7 Fluid overload
0.768 0.232 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.767 0.233 0.000
C78.2 Secondary malignant neoplasm of pleura
0.767 0.233 0.000
R20 Disturbances of skin sensation
0.766 0.234 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.766 0.234 0.000
N60 Benign mammary dysplasia
0.766 0.234 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.765 0.234 0.000
G62.9 Polyneuropathy, unspecified
0.761 0.239 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.761 0.239 0.000
E27 Other disorders of adrenal gland
0.760 0.239 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.760 0.240 0.000
H53.9 Visual disturbance, unspecified
0.759 0.241 0.000
R11 Nausea and vomiting
0.758 0.242 0.000
H33.0 Retinal detachment with retinal break
0.757 0.243 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.756 0.244 0.000
H21 Other disorders of iris and ciliary body
0.756 0.244 0.000
H26 Other cataract
0.755 0.245 0.000
C16.9 Stomach, unspecified
0.755 0.245 0.000
C51 Malignant neoplasm of vulva
0.754 0.246 0.000
D27 Benign neoplasm of ovary
0.754 0.246 0.000
D23.6 Skin of upper limb, including shoulder
0.753 0.247 0.000
D11 Benign neoplasm of major salivary glands
0.752 0.248 0.000
B18 Chronic viral hepatitis
0.751 0.249 0.000
N11 Chronic tubulo-interstitial nephritis
0.751 0.249 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.749 0.250 0.000
N25-N29 Other disorders of kidney and ureter
0.748 0.252 0.000
G30-G32 Other degenerative diseases of the nervous system
0.747 0.252 0.000
H02.9 Disorder of eyelid, unspecified
0.747 0.253 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.747 0.253 0.000
E88 Other metabolic disorders
0.746 0.253 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.744 0.256 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.744 0.256 0.000
H27 Other disorders of lens
0.743 0.256 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.743 0.257 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.743 0.257 0.000
N64 Other disorders of breast
0.743 0.257 0.000
R19.5 Other fecal abnormalities
0.739 0.261 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.738 0.262 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.738 0.262 0.000
C25.9 Pancreas, unspecified
0.738 0.262 0.000
C56 Malignant neoplasm of ovary
0.738 0.262 0.000
Z43.2 Attention to ileostomy
0.738 0.262 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.737 0.263 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.734 0.266 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.732 0.268 0.000
M05-M14 Inflammatory polyarthropathies
0.731 0.269 0.000
O30 Multiple gestation
0.728 0.272 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.728 0.272 0.000
O82 Single delivery by Caesarean section
0.728 0.272 0.000
M70-M79 Other soft tissue disorders
0.728 0.272 0.000
C77.1 Intrathoracic lymph nodes
0.728 0.272 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.728 0.272 0.000
H53.8 Other visual disturbances
0.727 0.273 0.000
O41 Other disorders of amniotic fluid and membranes
0.726 0.274 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.726 0.274 0.000
N21.0 Calculus in bladder
0.725 0.275 0.000
O42.9 Premature rupture of membranes, unspecified
0.725 0.275 0.000
A80-A89 Viral infections of the central nervous system
0.722 0.278 0.000
Chapter V Mental and behavioural disorders
0.721 0.279 0.000
C80 Malignant neoplasm without specification of site
0.721 0.279 0.000
Chapter XXII Codes for special purposes
0.720 0.280 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.720 0.280 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.719 0.281 0.000
N13.4 Hydroureter
0.718 0.281 0.000
H05 Disorders of orbit
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N61 Inflammatory disorders of breast
0.717 0.283 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.716 0.283 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.716 0.283 0.000
C21 Malignant neoplasm of anus and anal canal
0.716 0.283 0.000
C23 Malignant neoplasm of gallbladder
0.716 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.716 0.284 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.716 0.284 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.716 0.284 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.715 0.285 0.000
E40-E46 Malnutrition
0.715 0.285 0.000
O85-O92 Complications predominantly related to the puerperium
0.714 0.286 0.000
H04 Disorders of lachrymal system
0.714 0.286 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.713 0.287 0.000
D31 Benign neoplasm of eye and adnexa
0.713 0.287 0.000
D30 Benign neoplasm of urinary organs
0.713 0.287 0.000
D29 Benign neoplasm of male genital organs
0.713 0.287 0.000
D26 Other benign neoplasms of uterus
0.713 0.287 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.713 0.287 0.000
D19 Benign neoplasm of mesothelial tissue
0.713 0.287 0.000
D16 Benign neoplasm of bone and articular cartilage
0.713 0.287 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.713 0.287 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.713 0.287 0.000
H02.8 Other specified disorders of eyelid
0.713 0.287 0.000
O36.8 Maternal care for other specified foetal problems
0.712 0.288 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.711 0.289 0.000
N15 Other renal tubulo-interstitial diseases
0.711 0.289 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.711 0.289 0.000
N10 Acute tubulo-interstitial nephritis
0.711 0.289 0.000
M06 Other rheumatoid arthritis
0.711 0.289 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.711 0.289 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.711 0.289 0.000
M79.8 Other specified soft tissue disorders
0.709 0.291 0.000
C18.0 Caecum
0.709 0.291 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.708 0.292 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.708 0.292 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.708 0.292 0.000
E85 Amyloidosis
0.706 0.293 0.000
E84 Cystic fibrosis
0.706 0.293 0.000
E79 Disorders of purine and pyrimidine metabolism
0.706 0.293 0.000
E77 Disorders of glycoprotein metabolism
0.706 0.293 0.000
E76 Disorders of glycosaminoglycan metabolism
0.706 0.293 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.706 0.293 0.000
E74 Other disorders of carbohydrate metabolism
0.706 0.293 0.000
E73 Lactose intolerance
0.706 0.293 0.000
E72 Other disorders of amino-acid metabolism
0.706 0.293 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.706 0.293 0.000
E70 Disorders of aromatic amino-acid metabolism
0.706 0.293 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.706 0.293 0.000
D04 Carcinoma in situ of skin
0.706 0.294 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.705 0.295 0.000
O45 Premature separation of placenta [abruptio placentae]
0.704 0.296 0.000
O44 Placenta praevia
0.704 0.296 0.000
O43 Placental disorders
0.704 0.296 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.704 0.296 0.000
O33 Maternal care for known or suspected disproportion
0.704 0.296 0.000
O31 Complications specific to multiple gestation
0.704 0.296 0.000
O40 Polyhydramnios
0.704 0.296 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.704 0.296 0.000
E11 Non-insulin-dependent diabetes mellitus
0.704 0.296 0.000
H20 Iridocyclitis
0.703 0.297 0.000
G70-G73 Diseases of myoneural junction and muscle
0.703 0.297 0.000
O81 Single delivery by forceps and vacuum extractor
0.703 0.297 0.000
C77.9 Lymph node, unspecified
0.702 0.298 0.000
H54 Blindness and low vision
0.702 0.298 0.000
D32 Benign neoplasm of meninges
0.702 0.298 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.701 0.299 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.701 0.299 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.701 0.299 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.701 0.299 0.000
H44 Disorders of globe
0.701 0.299 0.000
H18 Other disorders of cornea
0.700 0.300 0.000
R13 Dysphagia
0.700 0.300 0.000
D23.7 Skin of lower limb, including hip
0.700 0.300 0.000
C18.8 Overlapping lesion of colon
0.698 0.302 0.000
C18.5 Splenic flexure
0.698 0.302 0.000
C18.1 Appendix
0.698 0.302 0.000
M06.9 Rheumatoid arthritis, unspecified
0.697 0.303 0.000
O47 False labour
0.697 0.303 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.696 0.304 0.000
E87.4 Mixed disorder of acid-base balance
0.696 0.304 0.000
E87.3 Alkalosis
0.696 0.304 0.000
D12.2 Ascending colon
0.695 0.305 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.694 0.306 0.000
D37.4 Colon
0.694 0.306 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.693 0.307 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.693 0.307 0.000
H25.8 Other senile cataract
0.692 0.308 0.000
Z48 Other surgical follow-up care
0.692 0.308 0.000
Z54 Convalescence
0.692 0.308 0.000
Z44 Fitting and adjustment of external prosthetic device
0.692 0.308 0.000
C18.6 Descending colon
0.692 0.308 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.691 0.309 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.691 0.309 0.000
Z43.1 Attention to gastrostomy
0.691 0.309 0.000
N99-N99 Other disorders of the genitourinary system
0.690 0.310 0.000
D35.1 Parathyroid gland
0.690 0.310 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.690 0.310 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.689 0.311 0.000
E00-E07 Disorders of thyroid gland
0.689 0.311 0.000
G93 Other disorders of brain
0.689 0.311 0.000
D10 Benign neoplasm of mouth and pharynx
0.688 0.312 0.000
E21.3 Hyperparathyroidism, unspecified
0.688 0.312 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.688 0.312 0.000
Z50.6 Orthoptic training
0.686 0.314 0.000
Z50.3 Drug rehabilitation
0.686 0.314 0.000
Z50.2 Alcohol rehabilitation
0.686 0.314 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.686 0.314 0.000
C17.9 Small intestine, unspecified
0.685 0.315 0.000
Y85 Sequelae of transport accidents
0.685 0.315 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.684 0.316 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.683 0.317 0.000
C53 Malignant neoplasm of cervix uteri
0.683 0.317 0.000
C58 Malignant neoplasm of placenta
0.683 0.317 0.000
C52 Malignant neoplasm of vagina
0.683 0.317 0.000
E22 Hyperfunction of pituitary gland
0.681 0.318 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.681 0.319 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.681 0.319 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.680 0.320 0.000
D12.8 Rectum
0.680 0.320 0.000
H53.2 Diplopia
0.680 0.320 0.000
B18.2 Chronic viral hepatitis C
0.680 0.320 0.000
Z52 Donors of organs and tissues
0.680 0.320 0.000
C25.0 Head of pancreas
0.679 0.321 0.000
R20.2 Paraesthesia of skin
0.678 0.322 0.000
H43.9 Disorder of vitreous body, unspecified
0.677 0.322 0.000
H43.2 Crystalline deposits in vitreous body
0.677 0.322 0.000
H43.0 Vitreous prolapse
0.677 0.322 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.677 0.323 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.676 0.324 0.000
C18.2 Ascending colon
0.675 0.325 0.000
N20.0 Calculus of kidney
0.674 0.326 0.000
C64-C68 Malignant neoplasms of urinary tract
0.674 0.326 0.000
Z12 Special screening examination for neoplasms
0.674 0.326 0.000
E28 Ovarian dysfunction
0.673 0.327 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.673 0.327 0.000
H31 Other disorders of choroid
0.673 0.327 0.000
H30 Chorioretinal inflammation
0.673 0.327 0.000
G61 Inflammatory polyneuropathy
0.672 0.328 0.000
B35-B49 Mycoses
0.672 0.328 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.670 0.330 0.000
O63.1 Prolonged second stage (of labour)
0.670 0.330 0.000
D03 Melanoma in situ
0.669 0.331 0.000
H43.1 Vitreous haemorrhage
0.668 0.332 0.000
C15.5 Lower third of oesophagus
0.668 0.332 0.000
C77.4 Inguinal and lower limb lymph nodes
0.668 0.332 0.000
G20-G26 Extrapyramidal and movement disorders
0.667 0.333 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.667 0.333 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.667 0.333 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.666 0.334 0.000
G41 Status epilepticus
0.666 0.334 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.665 0.334 0.000
N18 Chronic renal failure
0.665 0.335 0.000
Z43.9 Attention to unspecified artificial opening
0.663 0.336 0.000
Z43.8 Attention to other artificial openings
0.663 0.336 0.000
Z43.7 Attention to artificial vagina
0.663 0.336 0.000
Z43.5 Attention to cyctostomy
0.663 0.336 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.663 0.336 0.000
Z43.0 Attention to tracheostomy
0.663 0.336 0.000
H02.5 Other disorders affecting eyelid function
0.663 0.337 0.000
Z02 Examination and encounter for administrative purposes
0.662 0.338 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.662 0.338 0.000
E27.1 Primary adrenocortical insufficiency
0.660 0.340 0.000
E10.3 With ophthalmic complications
0.659 0.341 0.000
H50 Other strabismus
0.659 0.341 0.000
H52 Disorders of refraction and accommodation
0.659 0.341 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.659 0.341 0.000
H01 Other inflammation of eyelid
0.658 0.342 0.000
Z49.1 Extracorporeal dialysis
0.658 0.342 0.000
H25.2 Senile cataract, morgagnian type
0.656 0.343 0.000
D46 Myelodysplastic syndromes
0.656 0.344 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.656 0.344 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.656 0.344 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.656 0.344 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.656 0.344 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.656 0.344 0.000
E14 Unspecified diabetes mellitus
0.656 0.344 0.000
Z41 Procedures for purposes other than remedying health state
0.654 0.345 0.000
N60.0 Solitary cyst of breast
0.654 0.346 0.000
Chapter VIII Diseases of the ear and mastoid process
0.653 0.347 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.652 0.348 0.000
C16.8 Overlapping lesion of stomach
0.652 0.348 0.000
C16.6 Greater curvature of stomach, unspecified
0.652 0.348 0.000
C16.5 Lesser curvature of stomach, unspecified
0.652 0.348 0.000
C16.4 Pylorus
0.652 0.348 0.000
C16.3 Pyloric antrum
0.652 0.348 0.000
C16.2 Body of stomach
0.652 0.348 0.000
C16.1 Fundus of stomach
0.652 0.348 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.651 0.349 0.000
O16 Unspecified maternal hypertension
0.651 0.349 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.651 0.349 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.651 0.349 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.651 0.349 0.000
E89.5 Postprocedural testicular hypofunction
0.651 0.349 0.000
E89.4 Postprocedural ovarian failure
0.651 0.349 0.000
E89.3 Postprocedural hypopituitarism
0.651 0.349 0.000
E89.2 Postprocedural hypoparathyroidism
0.651 0.349 0.000
E89.1 Postprocedural hypoinsulinaemia
0.651 0.349 0.000
H02.3 Blepharochalasis
0.650 0.349 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.650 0.350 0.000
H02.6 Xanthelasma of eyelid
0.650 0.350 0.000
H02.2 Lagophthalmos
0.650 0.350 0.000
G45.4 Transient global amnesia
0.650 0.350 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.650 0.350 0.000
H11 Other disorders of conjunctiva
0.648 0.352 0.000
D14.0 Middle ear, nasal cavity and accessory sinuses
0.648 0.352 0.000
G44 Other headache syndromes
0.647 0.353 0.000
C22.9 Liver, unspecified
0.646 0.353 0.000
O82.1 Delivery by emergency Caesarean section
0.646 0.354 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.646 0.354 0.000
E34 Other endocrine disorders
0.646 0.354 0.000
E32 Diseases of thymus
0.646 0.354 0.000
E31 Polyglandular dysfunction
0.646 0.354 0.000
E30 Disorders of puberty, not elsewhere classified
0.646 0.354 0.000
E26 Hyperaldosteronism
0.646 0.354 0.000
E25 Adrenogenital disorders
0.646 0.354 0.000
E24 Cushing's syndrome
0.646 0.354 0.000
E20 Hypoparathyroidism
0.646 0.354 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.644 0.356 0.000
G47.8 Other sleep disorders
0.644 0.356 0.000
G47.4 Narcolepsy and cataplexy
0.644 0.356 0.000
G47.2 Disorders of the sleep-wake schedule
0.644 0.356 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.644 0.356 0.000
D37.7 Other digestive organs
0.644 0.356 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.644 0.356 0.000
E29 Testicular dysfunction
0.644 0.356 0.000
O63.9 Long labour, unspecified
0.643 0.357 0.000
A30-A49 Other bacterial diseases
0.643 0.357 0.000
C77.8 Lymph nodes of multiple regions
0.643 0.357 0.000
E10.4 With neurological complications
0.643 0.357 0.000
Z42 Follow-up care involving plastic surgery
0.642 0.357 0.000
Z45.8 Adjustment and management of other implanted devices
0.640 0.360 0.000
E13 Other specified diabetes mellitus
0.640 0.360 0.000
E12 Malnutrition-related diabetes mellitus
0.640 0.360 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.640 0.360 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.640 0.360 0.000
H17 Corneal scars and opacities
0.640 0.360 0.000
H16 Keratitis
0.640 0.360 0.000
H15 Disorders of sclera
0.640 0.360 0.000
V10-V19 Pedal cyclist injured in transport accident
0.638 0.362 0.000
C77.0 Lymph nodes of head, face and neck
0.638 0.362 0.000
Z45.1 Adjustment and management of infusion pump
0.637 0.363 0.000
G60 Hereditary and idiopathic neuropathy
0.636 0.364 0.000
G64 Other disorders of peripheral nervous system
0.636 0.364 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.636 0.364 0.000
C15.8 Overlapping lesion of oesophagus
0.636 0.364 0.000
C15.4 Middle third of oesophagus
0.636 0.364 0.000
C15.3 Upper third of oesophagus
0.636 0.364 0.000
C15.2 Abdominal part of oesophagus
0.636 0.364 0.000
C15.1 Thoracic part of oesophagus
0.636 0.364 0.000
C15.0 Cervical part of oesophagus
0.636 0.364 0.000
G12 Spinal muscular atrophy and related syndromes
0.636 0.364 0.000
H33.5 Other retinal detachments
0.635 0.365 0.000
H33.4 Traction detachment of retina
0.635 0.365 0.000
H33.1 Retinoschisis and retinal cysts
0.635 0.365 0.000
H26.9 Cataract, unspecified
0.634 0.366 0.000
B25-B34 Other viral diseases
0.634 0.366 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.633 0.367 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.633 0.367 0.000
B99-B99 Other infectious diseases
0.633 0.367 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.633 0.367 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.633 0.367 0.000
B65-B83 Helminthiases
0.633 0.367 0.000
B50-B64 Protozoal diseases
0.633 0.367 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.633 0.367 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.633 0.367 0.000
A75-A79 Rickettsioses
0.633 0.367 0.000
A70-A74 Other diseases caused by chlamydiae
0.633 0.367 0.000
A65-A69 Other spirochaetal diseases
0.633 0.367 0.000
A20-A28 Certain zoonotic bacterial diseases
0.633 0.367 0.000
A15-A19 Tuberculosis
0.633 0.367 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.633 0.367 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.632 0.367 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.632 0.368 0.000
Y85.0 Sequelae of motor-vehicle accident
0.632 0.368 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.631 0.369 0.000
H10 Conjunctivitis
0.630 0.370 0.000
Z50.8 Care involving use of rehabilitation procedures
0.629 0.370 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.629 0.370 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.629 0.371 0.000
D23.9 Skin, unspecified
0.629 0.371 0.000
D23.2 Skin of ear and external auricular canal
0.629 0.371 0.000
D23.0 Skin of lip
0.629 0.371 0.000
S60-S69 Injuries to the wrist and hand
0.628 0.372 0.000
N40-N51 Diseases of male genital organs
0.627 0.373 0.000
O36.9 Maternal care for foetal problem, unspecified
0.627 0.373 0.000
R19.6 Halitosis
0.627 0.373 0.000
R19.3 Abdominal rigidity
0.627 0.373 0.000
R19.2 Visible peristalsis
0.627 0.373 0.000
R19.1 Abnormal bowel sounds
0.627 0.373 0.000
D23.4 Skin of scalp and neck
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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