TreeWAS – Variant ID: rs17450512

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
J40-J47 Chronic lower respiratory diseases	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
J43 Emphysema	0.999	0.001
Chapter IV Endocrine, nutritional and metabolic diseases	0.999	0.001
J44 Other chronic obstructive pulmonary disease	0.999	0.001
J43.9 Emphysema, unspecified	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.993	0.007
Chapter IX Diseases of the circulatory system	0.993	0.007
E70-E90 Metabolic disorders	0.991	0.009
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.987	0.013
M05-M14 Inflammatory polyarthropathies	0.986	0.014
E87 Other disorders of fluid, electrolyte and acid-base balance	0.984	0.016
Chapter V Mental and behavioural disorders	0.984	0.016
M80-M85 Disorders of bone density and structure	0.981	0.019
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.979	0.021
M81 Osteoporosis without pathological fracture	0.972	0.028
M06 Other rheumatoid arthritis	0.972	0.028
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.971	0.029
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.963	0.037
M06.9 Rheumatoid arthritis, unspecified	0.963	0.037
M81.9 Osteoporosis, unspecified	0.961	0.039
Chapter VI Diseases of the nervous system	0.958	0.042
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.956	0.044
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.953	0.047
E86 Volume depletion	0.951	0.049
E87.2 Acidosis	0.944	0.056
J44.9 Chronic obstructive pulmonary disease, unspecified	0.944	0.056
Chapter XII Diseases of the skin and subcutaneous tissue	0.943	0.057
L20-L30 Dermatitis and eczema	0.938	0.062
Chapter VII Diseases of the eye and adnexa	0.934	0.066
F10 Mental and behavioural disorders due to use of alcohol	0.933	0.067
Q60-Q64 Congenital malformations of the urinary system	0.933	0.067
L30 Other dermatitis	0.933	0.067
L30.9 Dermatitis, unspecified	0.929	0.071
J30-J39 Other diseases of upper respiratory tract	0.928	0.072
E10-E14 Diabetes mellitus	0.924	0.076
J44.8 Other specified chronic obstructive pulmonary disease	0.920	0.080
I80 Phlebitis and thrombophlebitis	0.915	0.085
E20-E35 Disorders of other endocrine glands	0.915	0.085
Chapter I Certain infectious and parasitic diseases	0.914	0.086
E87.1 Hypo-osmolality and hyponatraemia	0.913	0.087
I84 Haemorrhoids	0.913	0.087
I70-I79 Diseases of arteries, arterioles and capillaries	0.911	0.089
I84.8 Unspecified haemorrhoids with other complications	0.910	0.090
E11 Non-insulin-dependent diabetes mellitus	0.909	0.091
M81.90 Osteoporosis, unspecified (Multiple sites)	0.905	0.095
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.902	0.098
T93 Sequelae of injuries of lower limb	0.900	0.100
S10-S19 Injuries to the neck	0.899	0.101
J33 Nasal polyp	0.897	0.103
S50-S59 Injuries to the elbow and forearm	0.896	0.104
J47 Bronchiectasis	0.892	0.108
Q61 Cystic kidney disease	0.890	0.110
F10.3 Withdrawal state	0.890	0.110
I05-I09 Chronic rheumatic heart diseases	0.888	0.112
E50-E64 Other nutritional deficiencies	0.886	0.114
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.885	0.115
H30-H36 Disorders of choroid and retina	0.884	0.116
G30-G32 Other degenerative diseases of the nervous system	0.875	0.125
T20-T25 Burns and corrosions of external body surface, specified by site	0.873	0.127
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.872	0.128
E11.3 With ophthalmic complications	0.869	0.131
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.868	0.132
M81.99 Osteoporosis, unspecified (Site unspecified)	0.864	0.136
M10 Gout	0.863	0.137
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.862	0.138
Q80-Q89 Other congenital malformations	0.857	0.143
S90-S99 Injuries to the ankle and foot	0.853	0.147
J32 Chronic sinusitis	0.850	0.150
I30-I52 Other forms of heart disease	0.849	0.151
J33.9 Nasal polyp, unspecified	0.848	0.152
Q38-Q45 Other congenital malformations of the digestive system	0.848	0.152
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.847	0.153
H34 Retinal vascular occlusions	0.847	0.153
B95-B98 Bacterial, viral and other infectious agents	0.847	0.153
T91 Sequelae of injuries of neck and trunk	0.844	0.156
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.843	0.157
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.842	0.158
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.840	0.160
Q61.0 Congenital single renal cyst	0.840	0.160
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.837	0.163
E88 Other metabolic disorders	0.836	0.164
T66-T78 Other and unspecified effects of external causes	0.833	0.167
I74 Arterial embolism and thrombosis	0.832	0.168
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.832	0.168
I84.4 External haemorrhoids with other complications	0.831	0.169
J32.9 Chronic sinusitis, unspecified	0.829	0.171
J43.2 Centrilobular emphysema	0.829	0.171
F17 Mental and behavioural disorders due to use of tobacco	0.829	0.171
S20-S29 Injuries to the thorax	0.826	0.174
E11.4 With neurological complications	0.825	0.175
E87.6 Hypokalaemia	0.818	0.182
F10.2 Dependence syndrome	0.816	0.184
I38 Endocarditis, valve unspecified	0.815	0.185
T93.1 Sequelae of fracture of femur	0.814	0.186
L80-L99 Other disorders of the skin and subcutaneous tissue	0.813	0.187
Chapter XX External causes of morbidity and mortality	0.811	0.189
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.811	0.189
L29 Pruritus	0.809	0.191
I08 Multiple valve diseases	0.806	0.194
E11.5 With peripheral circulatory complications	0.805	0.195
J31.0 Chronic rhinitis	0.804	0.196
S19 Other and unspecified injuries of neck	0.803	0.197
B99-B99 Other infectious diseases	0.803	0.197
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.803	0.197
H43-H45 Disorders of vitreous body and globe	0.803	0.197
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.802	0.198
F00-F09 Organic, including symptomatic, mental disorders	0.801	0.199
Q20-Q28 Congenital malformations of the circulatory system	0.801	0.199
J42 Unspecified chronic bronchitis	0.799	0.201
G00-G09 Inflammatory diseases of the central nervous system	0.799	0.201
M00-M03 Infectious arthropathies	0.799	0.201
M81.4 Drug-induced osteoporosis	0.798	0.202
F40-F48 Neurotic, stress-related and somatoform disorders	0.797	0.203
I45 Other conduction disorders	0.797	0.203
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.795	0.205
S32 Fracture of lumbar spine and pelvis	0.795	0.205
E24 Cushing's syndrome	0.795	0.205
G90-G99 Other disorders of the nervous system	0.789	0.211
H36 Retinal disorders in diseases classified elsewhere	0.789	0.211
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.786	0.213
M11 Other crystal arthropathies	0.786	0.214
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.786	0.214
M07 Psoriatic and enteropathic arthropathies	0.785	0.215
S40-S49 Injuries to the shoulder and upper arm	0.783	0.217
E22 Hyperfunction of pituitary gland	0.782	0.217
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.782	0.218
I45.1 Other and unspecified right bundle-branch block	0.780	0.220
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.777	0.223
M10.9 Gout, unspecified	0.775	0.225
L97 Ulcer of lower limb, not elsewhere classified	0.774	0.226
I35 Nonrheumatic aortic valve disorders	0.774	0.226
I77 Other disorders of arteries and arterioles	0.773	0.227
F17.2 Dependence syndrome	0.769	0.231
I84.0 Internal thrombosed haemorrhoids	0.768	0.232
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.767	0.233
H55-H59 Other disorders of eye and adnexa	0.764	0.236
E40-E46 Malnutrition	0.764	0.236
M60-M63 Disorders of muscles	0.763	0.237
T95 Sequelae of burns, corrosions and frostbite	0.760	0.240
E87.3 Alkalosis	0.760	0.240
H34.8 Other retinal vascular occlusions	0.758	0.242
B15-B19 Viral hepatitis	0.757	0.243
J36 Peritonsillar abscess	0.757	0.243
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.756	0.244
M91-M94 Chondropathies	0.755	0.245
E55 Vitamin D deficiency	0.755	0.245
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.754	0.246
I85 Oesophageal varices	0.754	0.246
Q61.3 Polycystic kidney, unspecified	0.754	0.246
M85 Other disorders of bone density and structure	0.754	0.246
T93.0 Sequelae of open wound of lower limb	0.752	0.248
H34.2 Other retinal artery occlusions	0.752	0.248
F11 Mental and behavioural disorders due to use of opioids	0.752	0.248
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.751	0.249
F12 Mental and behavioural disorders due to use of cannabinoids	0.751	0.249
M81.96 Osteoporosis, unspecified (Lower leg)	0.751	0.249
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.750	0.250
G20-G26 Extrapyramidal and movement disorders	0.748	0.252
G31.9 Degenerative disease of nervous system, unspecified	0.748	0.252
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.746	0.254
E26 Hyperaldosteronism	0.745	0.255
T98 Sequelae of other and unspecified effects of external causes	0.743	0.257
J33.0 Polyp of nasal cavity	0.743	0.257
I73 Other peripheral vascular diseases	0.742	0.258
G60 Hereditary and idiopathic neuropathy	0.742	0.258
I87 Other disorders of veins	0.741	0.259
I60-I69 Cerebrovascular diseases	0.740	0.260
E73 Lactose intolerance	0.740	0.260
L29.9 Pruritus, unspecified	0.740	0.260
I35.1 Aortic (valve) insufficiency	0.738	0.262
M80 Osteoporosis with pathological fracture	0.736	0.264
S19.9 Unspecified injury of neck	0.735	0.265
S92 Fracture of foot, except ankle	0.735	0.265
E53 Deficiency of other B group vitamins	0.735	0.265
T23 Burn and corrosion of wrist and hand	0.734	0.266
I05 Rheumatic mitral valve diseases	0.734	0.266
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.733	0.267
G70-G73 Diseases of myoneural junction and muscle	0.732	0.268
S51 Open wound of forearm	0.732	0.268
M81.2 Osteoporosis of disuse	0.731	0.269
F10.5 Psychotic disorder	0.731	0.269
T91.8 Sequelae of other specified injuries of neck and trunk	0.730	0.270
M65-M68 Disorders of synovium and tendon	0.728	0.272
S31 Open wound of abdomen, lower back and pelvis	0.727	0.273
S22 Fracture of rib(s), sternum and thoracic spine	0.726	0.274
E20 Hypoparathyroidism	0.726	0.274
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.725	0.275
I84.1 Internal haemorrhoids with other complications	0.725	0.275
B99 Other and unspecified infectious diseases	0.724	0.276
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.724	0.276
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.723	0.277
M86-M90 Other osteopathies	0.723	0.277
F10.4 Withdrawal state with delirium	0.722	0.278
H36.0 Diabetic retinopathy	0.721	0.279
D68 Other coagulation defects	0.720	0.280
D80-D89 Certain disorders involving the immune mechanism	0.719	0.281
E11.2 With renal complications	0.718	0.282
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.717	0.283
H46-H48 Disorders of optic nerve and visual pathways	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
J41 Simple and mucopurulent chronic bronchitis	0.717	0.283
F10.6 Amnesic syndrome	0.717	0.283
J43.8 Other emphysema	0.716	0.284
J43.1 Panlobular emphysema	0.716	0.284
J43.0 MacLeod's syndrome	0.716	0.284
I95-I99 Other and unspecified disorders of the circulatory system	0.716	0.284
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.716	0.284
B90-B94 Sequelae of infectious and parasitic diseases	0.716	0.284
F43 Reaction to severe stress, and adjustment disorders	0.715	0.285
T33-T35 Frostbite	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
B20-B24 Human immunodeficiency virus [HIV] disease	0.715	0.285
T00-T07 Injuries involving multiple body regions	0.714	0.286
I00-I02 Acute rheumatic fever	0.712	0.288
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.710	0.290
E85 Amyloidosis	0.710	0.290
E84 Cystic fibrosis	0.710	0.290
E79 Disorders of purine and pyrimidine metabolism	0.710	0.290
E77 Disorders of glycoprotein metabolism	0.710	0.290
E76 Disorders of glycosaminoglycan metabolism	0.710	0.290
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.710	0.290
E72 Other disorders of amino-acid metabolism	0.710	0.290
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.710	0.290
E70 Disorders of aromatic amino-acid metabolism	0.710	0.290
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.710	0.290
B65-B83 Helminthiases	0.709	0.290
Q60 Renal agenesis and other reduction defects of kidney	0.709	0.291
L89 Decubitus ulcer	0.708	0.292
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.708	0.292
Q35-Q37 Cleft lip and cleft palate	0.708	0.292
Q30-Q34 Congenital malformations of the respiratory system	0.708	0.292
M12 Other specific arthropathies	0.707	0.293
M09 Juvenile arthritis in diseases classified elsewhere	0.707	0.293
M08 Juvenile arthritis	0.707	0.293
J33.8 Other polyp of sinus	0.707	0.293
H53-H54 Visual disturbances and blindness	0.706	0.294
E87.4 Mixed disorder of acid-base balance	0.705	0.295
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.705	0.295
F70-F79 Mental retardation	0.705	0.295
M83 Adult osteomalacia	0.703	0.297
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.702	0.298
M06.0 Seronegative rheumatoid arthritis	0.702	0.298
L30.8 Other specified dermatitis	0.702	0.298
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.701	0.299
D68.2 Hereditary deficiency of other clotting factors	0.701	0.299
H20 Iridocyclitis	0.700	0.300
S54 Injury of nerves at forearm level	0.700	0.300
J00-J06 Acute upper respiratory infections	0.700	0.300
Q89 Other congenital malformations, not elsewhere classified	0.698	0.302
X60-X84 Intentional self-harm	0.698	0.302
I70 Atherosclerosis	0.697	0.303
M81.8 Other osteoporosis	0.697	0.303
M81.6 Localised osteoporosis [Lequesne]	0.697	0.303
M81.5 Idiopathic osteoporosis	0.697	0.303
M81.3 Postsurgical malabsorption osteoporosis	0.697	0.303
M81.1 Postoophorectomy osteoporosis	0.697	0.303
M81.0 Postmenopausal osteoporosis	0.697	0.303
M06.8 Other specified rheumatoid arthritis	0.697	0.303
M06.3 Rheumatoid nodule	0.697	0.303
M06.2 Rheumatoid bursitis	0.697	0.303
M06.1 Adult-onset Still's disease	0.697	0.303
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.696	0.303
F18 Mental and behavioural disorders due to use of volatile solvents	0.696	0.303
F16 Mental and behavioural disorders due to use of hallucinogens	0.696	0.303
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.696	0.303
F14 Mental and behavioural disorders due to use of cocaine	0.696	0.303
Chapter XXII Codes for special purposes	0.695	0.305
T93.2 Sequelae of other fractures of lower limb	0.694	0.306
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.693	0.306
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.693	0.307
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.693	0.307
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.693	0.307
S00-S09 Injuries to the head	0.693	0.307
T68 Hypothermia	0.692	0.308
Q00-Q07 Congenital malformations of the nervous system	0.691	0.308
G12 Spinal muscular atrophy and related syndromes	0.691	0.309
F60-F69 Disorders of adult personality and behaviour	0.691	0.309
M06.98 Rheumatoid arthritis, unspecified (Other)	0.691	0.309
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.691	0.309
B50-B64 Protozoal diseases	0.691	0.309
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.690	0.310
Q50-Q56 Congenital malformations of genital organs	0.690	0.310
M81.94 Osteoporosis, unspecified (Hand)	0.689	0.311
M81.93 Osteoporosis, unspecified (Forearm)	0.689	0.311
M81.92 Osteoporosis, unspecified (Upper arm)	0.689	0.311
M81.91 Osteoporosis, unspecified (Shoulder region)	0.689	0.311
D55-D59 Haemolytic anaemias	0.687	0.313
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.686	0.314
G63 Polyneuropathy in diseases classified elsewhere	0.686	0.314
T94 Sequelae of injuries involving multiple and unspecified body regions	0.686	0.314
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.686	0.314
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.686	0.314
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.685	0.315
E74 Other disorders of carbohydrate metabolism	0.684	0.315
I72 Other aneurysm	0.684	0.315
L84 Corns and callosities	0.684	0.316
I77.6 Arteritis, unspecified	0.684	0.316
M13 Other arthritis	0.683	0.317
J46 Status asthmaticus	0.681	0.319
M81.98 Osteoporosis, unspecified (Other)	0.680	0.320
G60.8 Other hereditary and idiopathic neuropathies	0.680	0.320
F29 Unspecified nonorganic psychosis	0.680	0.320
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.679	0.321
S27 Injury of other and unspecified intrathoracic organs	0.678	0.322
S40 Superficial injury of shoulder and upper arm	0.677	0.323
E11.1 With ketoacidosis	0.677	0.323
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.676	0.324
L10-L14 Bullous disorders	0.676	0.324
E11.0 With coma	0.676	0.324
F05 Delirium, not induced by alcohol and other psychoactive substances	0.675	0.325
E23 Hypofunction and other disorders of pituitary gland	0.675	0.325
G40-G47 Episodic and paroxysmal disorders	0.674	0.326
G93 Other disorders of brain	0.674	0.326
S56 Injury of muscle and tendon at forearm level	0.673	0.327
J37 Chronic laryngitis and laryngotracheitis	0.673	0.327
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.673	0.327
L25 Unspecified contact dermatitis	0.672	0.328
L24 Irritant contact dermatitis	0.672	0.328
L23 Allergic contact dermatitis	0.672	0.328
L21 Seborrhoeic dermatitis	0.672	0.328
L20 Atopic dermatitis	0.672	0.328
L26 Exfoliative dermatitis	0.672	0.328
L22 Diaper [napkin] dermatitis	0.672	0.328
G95 Other diseases of spinal cord	0.671	0.329
S14 Injury of nerves and spinal cord at neck level	0.671	0.329
I35.9 Aortic valve disorder, unspecified	0.669	0.331
F10.8 Other mental and behavioural disorders	0.669	0.331
F10.7 Residual and late-onset psychotic disorder	0.669	0.331
Q64 Other congenital malformations of urinary system	0.669	0.331
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.669	0.331
H34.1 Central retinal artery occlusion	0.669	0.331
L30.5 Pityriasis alba	0.669	0.331
L30.4 Erythema intertrigo	0.669	0.331
L30.3 Infective dermatitis	0.669	0.331
L30.2 Cutaneous autosensitisation	0.669	0.331
L30.1 Dyshidrosis [pompholyx]	0.669	0.331
L30.0 Nummular dermatitis	0.669	0.331
G31.2 Degeneration of nervous system due to alcohol	0.668	0.332
T90 Sequelae of injuries of head	0.668	0.332
J32.8 Other chronic sinusitis	0.668	0.332
G06 Intracranial and intraspinal abscess and granuloma	0.667	0.333
S11 Open wound of neck	0.667	0.333
I77.8 Other specified disorders of arteries and arterioles	0.666	0.334
H43 Disorders of vitreous body	0.666	0.334
I08.0 Disorders of both mitral and aortic valves	0.666	0.334
Q23 Congenital malformations of aortic and mitral valves	0.665	0.335
S99 Other and unspecified injuries of ankle and foot	0.665	0.335
S50 Superficial injury of forearm	0.665	0.335
S10 Superficial injury of neck	0.663	0.337
E16 Other disorders of pancreatic internal secretion	0.663	0.337
J31.2 Chronic pharyngitis	0.663	0.337
E24.9 Cushing's syndrome, unspecified	0.662	0.338
E12 Malnutrition-related diabetes mellitus	0.662	0.338
Q39 Congenital malformations of oesophagus	0.662	0.338
E28 Ovarian dysfunction	0.662	0.338
T20 Burn and corrosion of head and neck	0.662	0.338
L88 Pyoderma gangrenosum	0.662	0.338
Q28 Other congenital malformations of circulatory system	0.661	0.339
M05 Seropositive rheumatoid arthritis	0.661	0.339
E55.9 Vitamin D deficiency, unspecified	0.660	0.340
F80-F89 Disorders of psychological development	0.660	0.340
M00 Pyogenic arthritis	0.659	0.340
H55 Nystagmus and other irregular eye movements	0.659	0.341
I88 Nonspecific lymphadenitis	0.659	0.341
M82 Osteoporosis in diseases classified elsewhere	0.658	0.342
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.658	0.342
S96 Injury of muscle and tendon at ankle and foot level	0.658	0.342
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.658	0.342
M14 Arthropathies in other diseases classified elsewhere	0.657	0.342
H50 Other strabismus	0.657	0.343
S32.5 Fracture of pubis	0.656	0.343
S32.7 Multiple fractures of lumbar spine and pelvis	0.656	0.344
E35 Disorders of endocrine glands in diseases classified elsewhere	0.656	0.344
E32 Diseases of thymus	0.656	0.344
E31 Polyglandular dysfunction	0.656	0.344
E30 Disorders of puberty, not elsewhere classified	0.656	0.344
E25 Adrenogenital disorders	0.656	0.344
H40-H42 Glaucoma	0.656	0.344
B85-B89 Pediculosis, acariasis and other infestations	0.655	0.345
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.655	0.345
A75-A79 Rickettsioses	0.655	0.345
A70-A74 Other diseases caused by chlamydiae	0.655	0.345
A65-A69 Other spirochaetal diseases	0.655	0.345
A20-A28 Certain zoonotic bacterial diseases	0.655	0.345
A15-A19 Tuberculosis	0.655	0.345
S36 Injury of intra-abdominal organs	0.655	0.345
T63 Toxic effect of contact with venomous animals	0.654	0.345
E29 Testicular dysfunction	0.654	0.346
Q85 Phakomatoses, not elsewhere classified	0.654	0.346
F03 Unspecified dementia	0.654	0.346
T79-T79 Certain early complications of trauma	0.654	0.346
E11.7 With multiple complications	0.652	0.348
L27 Dermatitis due to substances taken internally	0.652	0.348
I86 Varicose veins of other sites	0.651	0.349
Q63 Other congenital malformations of kidney	0.651	0.349
Q82 Other congenital malformations of skin	0.651	0.349
S12 Fracture of neck	0.651	0.349
E87.5 Hyperkalaemia	0.650	0.350
M81.49 Drug-induced osteoporosis (Site unspecified)	0.649	0.351
T23.3 Burn of third degree of wrist and hand	0.649	0.351
E24.2 Drug-induced Cushing's syndrome	0.648	0.352
I09 Other rheumatic heart diseases	0.648	0.352
S22.4 Multiple fractures of ribs	0.648	0.352
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.647	0.353
S51.0 Open wound of elbow	0.647	0.353
F13.2 Dependence syndrome	0.647	0.353
S52 Fracture of forearm	0.647	0.353
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.647	0.353
S37 Injury of urinary and pelvic organs	0.647	0.353
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.647	0.353
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.647	0.353
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.647	0.353
H44 Disorders of globe	0.646	0.354
I45.8 Other specified conduction disorders	0.646	0.354
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.645	0.354
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.645	0.354
T93.4 Sequelae of injury of nerve of lower limb	0.645	0.354
I10-I15 Hypertensive diseases	0.645	0.355
S17 Crushing injury of neck	0.644	0.356
S15 Injury of blood vessels at neck level	0.644	0.356
S18 Traumatic amputation at neck level	0.644	0.356
S16 Injury of muscle and tendon at neck level	0.644	0.356
T59 Toxic effect of other gases, fumes and vapours	0.644	0.356
T91.9 Sequelae of unspecified injury of neck and trunk	0.643	0.357
J33.1 Polypoid sinus degeneration	0.643	0.357
G30 Alzheimer's disease	0.643	0.357
M11.2 Other chondrocalcinosis	0.643	0.357
I87.2 Venous insufficiency (chronic) (peripheral)	0.643	0.357
S59 Other and unspecified injuries of forearm	0.642	0.358
S58 Traumatic amputation of forearm	0.642	0.358
S57 Crushing injury of forearm	0.642	0.358
S55 Injury of blood vessels at forearm level	0.642	0.358
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.642	0.358
F99-F99 Unspecified mental disorder	0.642	0.358
T15-T19 Effects of foreign body entering through natural orifice	0.642	0.358
I67 Other cerebrovascular diseases	0.641	0.359
M07.3 Other psoriatic arthropathies	0.640	0.360
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.640	0.360
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.639	0.361
I47 Paroxysmal tachycardia	0.639	0.361
Q61.9 Cystic kidney disease, unspecified	0.638	0.362
Q61.8 Other cystic kidney diseases	0.638	0.362
Q61.5 Medullary cystic kidney	0.638	0.362
Q61.4 Renal dysplasia	0.638	0.362
Q61.1 Polycystic kidney, infantile type	0.638	0.362
V10-V19 Pedal cyclist injured in transport accident	0.638	0.362
S70-S79 Injuries to the hip and thigh	0.637	0.363
I06 Rheumatic aortic valve diseases	0.637	0.363
L80 Vitiligo	0.636	0.364
T78 Adverse effects, not elsewhere classified	0.636	0.364
E64 Sequelae of malnutrition and other nutritional deficiencies	0.636	0.364
E63 Other nutritional deficiencies	0.636	0.364
E56 Other vitamin deficiencies	0.636	0.364
E51 Thiamine deficiency	0.636	0.364
E50 Vitamin A deficiency	0.636	0.364
E60 Dietary zinc deficiency	0.636	0.364
E59 Dietary selenium deficiency	0.636	0.364
E58 Dietary calcium deficiency	0.636	0.364
E54 Ascorbic acid deficiency	0.636	0.364
E52 Niacin deficiency [pellagra]	0.636	0.364
E11.6 With other specified complications	0.636	0.364
I33 Acute and subacute endocarditis	0.636	0.364
M10.90 Gout, unspecified (Multiple sites)	0.635	0.365
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.635	0.365
W00-W19 Falls	0.635	0.365
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.634	0.366
H32 Chorioretinal disorders in diseases classified elsewhere	0.633	0.366
H30 Chorioretinal inflammation	0.633	0.366
X58-X59 Accidental exposure to other and unspecified factors	0.633	0.367
J09-J18 Influenza and pneumonia	0.633	0.367
E61 Deficiency of other nutrient elements	0.633	0.367
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.632	0.368
M84 Disorders of continuity of bone	0.632	0.368
T91.3 Sequelae of injury of spinal cord	0.632	0.368
D70-D77 Other diseases of blood and blood-forming organs	0.631	0.369
W50-W64 Exposure to animate mechanical forces	0.631	0.369
L91 Hypertrophic disorders of skin	0.631	0.369
H53 Visual disturbances	0.631	0.369
M10.96 Gout, unspecified (Lower leg)	0.630	0.370
I08.2 Disorders of both aortic and tricuspid valves	0.630	0.370
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.629	0.370
I85.0 Oesophageal varices with bleeding	0.629	0.371
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.627	0.373
T25 Burn and corrosion of ankle and foot	0.626	0.374
T21 Burn and corrosion of trunk	0.626	0.374
S90 Superficial injury of ankle and foot	0.626	0.374
B15 Acute hepatitis A	0.626	0.374
I71 Aortic aneurysm and dissection	0.626	0.374
F10.9 Unspecified mental and behavioural disorder	0.625	0.375
J20-J22 Other acute lower respiratory infections	0.625	0.375
E11.8 With unspecified complications	0.625	0.375
F42 Obsessive-compulsive disorder	0.625	0.375
E14 Unspecified diabetes mellitus	0.625	0.375
X40-X49 Accidental poisoning by and exposure to noxious substances	0.624	0.376
M40-M43 Deforming dorsopathies	0.624	0.376
E26.0 Primary hyperaldosteronism	0.624	0.376
L94 Other localised connective tissue disorders	0.624	0.376

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations