TreeWAS – Variant ID: rs17504106

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S06.20 Diffuse brain injury (without open intracranial wound)	0.067	0.933	0.000
S06.2 Diffuse brain injury	0.063	0.937	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.060	0.940	0.000
S06 Intracranial injury	0.060	0.940	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.060	0.940	0.000
S06.8 Other intracranial injuries	0.052	0.947	0.000
S06.1 Traumatic cerebral oedema	0.050	0.950	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.047	0.953	0.000
O48 Prolonged pregnancy	0.000	0.953	0.047
S06.21 Diffuse brain injury (with open intracranial wound)	0.045	0.955	0.000
S06.3 Focal brain injury	0.045	0.955	0.000
S06.4 Epidural haemorrhage	0.044	0.956	0.000
S06.9 Intracranial injury, unspecified	0.044	0.956	0.000
S06.7 Intracranial injury with prolonged coma	0.043	0.956	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.043	0.957	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.043	0.957	0.000
S06.5 Traumatic subdural haemorrhage	0.042	0.958	0.000
Z00.0 General medical examination	0.000	0.961	0.039
S06.81 Other intracranial injuries (with open intracranial wound)	0.038	0.962	0.000
S06.0 Concussion	0.037	0.962	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.000	0.963	0.037
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.036	0.964	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.000	0.966	0.034
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.966	0.034
S06.30 Focal brain injury (without open intracranial wound)	0.034	0.966	0.000
Z91.5 Personal history of self-harm	0.033	0.967	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.033	0.967	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.032	0.968	0.000
O32.8 Maternal care for other malpresentation of foetus	0.000	0.968	0.032
D03 Melanoma in situ	0.000	0.968	0.032
S06.41 Epidural haemorrhage (with open intracranial wound)	0.032	0.968	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.031	0.968	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.031	0.968	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.031	0.969	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.031	0.969	0.000
D03.4 Melanoma in situ of scalp and neck	0.000	0.969	0.031
O42 Premature rupture of membranes	0.000	0.970	0.030
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.030	0.970	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.000	0.971	0.029
O40 Polyhydramnios	0.000	0.971	0.029
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.028	0.972	0.000
O32.0 Maternal care for unstable lie	0.000	0.972	0.028
O41 Other disorders of amniotic fluid and membranes	0.000	0.973	0.027
S06.01 Concussion (with open intracranial wound)	0.027	0.973	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.000	0.973	0.027
O44 Placenta praevia	0.000	0.974	0.026
O42.9 Premature rupture of membranes, unspecified	0.000	0.974	0.026
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.000	0.974	0.026
O32.2 Maternal care for transverse and oblique lie	0.000	0.974	0.026
O32.1 Maternal care for breech presentation	0.000	0.974	0.026
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.974	0.026
O32.4 Maternal care for high head at term	0.000	0.975	0.025
O45 Premature separation of placenta [abruptio placentae]	0.000	0.975	0.025
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.975	0.025
D03.2 Melanoma in situ of ear and external auricular canal	0.000	0.975	0.025
O36 Maternal care for other known or suspected foetal problems	0.000	0.976	0.024
D03.5 Melanoma in situ of trunk	0.000	0.976	0.024
D03.9 Melanoma in situ, unspecified	0.000	0.977	0.023
D03.8 Melanoma in situ of other sites	0.000	0.977	0.023
D03.1 Melanoma in situ of eyelid, including canthus	0.000	0.977	0.023
D03.0 Melanoma in situ of lip	0.000	0.977	0.023
O32.6 Maternal care for compound presentation	0.000	0.977	0.023
O47 False labour	0.000	0.977	0.023
O32.3 Maternal care for face, brow and chin presentation	0.000	0.977	0.023
O44.1 Placenta praevia with haemorrhage	0.000	0.977	0.023
O36.4 Maternal care for intra-uterine death	0.000	0.977	0.023
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.977	0.023
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.000	0.978	0.022
O33 Maternal care for known or suspected disproportion	0.000	0.978	0.022
O31 Complications specific to multiple gestation	0.000	0.979	0.021
O43 Placental disorders	0.000	0.979	0.021
S06.00 Concussion (without open intracranial wound)	0.021	0.979	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.000	0.979	0.021
O47.0 False labour before 37 completed weeks of gestation	0.000	0.979	0.021
O36.8 Maternal care for other specified foetal problems	0.000	0.979	0.021
O41.1 Infection of amniotic sac and membranes	0.000	0.980	0.020
O30 Multiple gestation	0.000	0.981	0.019
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.981	0.019
O36.5 Maternal care for poor foetal growth	0.000	0.981	0.019
O45.9 Premature separation of placenta, unspecified	0.000	0.981	0.019
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.981	0.019
O36.1 Maternal care for other isoimmunisation	0.000	0.982	0.018
O45.8 Other premature separation of placenta	0.000	0.982	0.018
O45.0 Premature separation of placenta with coagulation defect	0.000	0.982	0.018
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.982	0.018
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.982	0.018
O36.2 Maternal care for hydrops foetalis	0.000	0.982	0.018
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.982	0.018
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.983	0.017
O47.9 False labour, unspecified	0.000	0.983	0.017
O34.1 Maternal care for tumour of corpus uteri	0.000	0.983	0.017
O34.8 Maternal care for other abnormalities of pelvic organs	0.000	0.983	0.017
D03.7 Melanoma in situ of lower limb, including hip	0.000	0.983	0.017
O34.7 Maternal care for abnormality of vulva and perineum	0.000	0.984	0.016
O33.8 Maternal care for disproportion of other origin	0.000	0.984	0.016
O33.7 Maternal care for disproportion due to other foetal deformities	0.000	0.984	0.016
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.000	0.984	0.016
O33.5 Maternal care for disproportion due to unusually large foetus	0.000	0.984	0.016
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.000	0.984	0.016
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.000	0.984	0.016
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.000	0.984	0.016
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.000	0.984	0.016
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.000	0.984	0.016
O41.0 Oligohydramnios	0.000	0.984	0.016
O43.8 Other placental disorders	0.000	0.984	0.016
O31.1 Continuing pregnancy after abortion of one foetus or more	0.000	0.984	0.015
O31.0 Papyraceous foetus	0.000	0.984	0.015
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.984	0.015
O43.2 Morbidly adherent placenta	0.000	0.984	0.015
O43.0 Placental transfusion syndromes	0.000	0.984	0.015
O34.0 Maternal care for congenital malformation of uterus	0.000	0.985	0.015
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.000	0.985	0.015
O34.6 Maternal care for abnormality of vagina	0.000	0.985	0.015
O34.3 Maternal care for cervical incompetence	0.000	0.985	0.015
O31.8 Other complications specific to multiple gestation	0.000	0.985	0.014
O36.6 Maternal care for excessive foetal growth	0.000	0.985	0.014
O30.1 Triplet pregnancy	0.000	0.986	0.014
O30.9 Multiple gestation, unspecified	0.000	0.986	0.014
O30.8 Other multiple gestation	0.000	0.986	0.014
O30.2 Quadruplet pregnancy	0.000	0.986	0.014
O43.1 Malformation of placenta	0.000	0.986	0.014
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.986	0.014
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.986	0.014
O34.5 Maternal care for other abnormalities of gravid uterus	0.000	0.986	0.013
O36.9 Maternal care for foetal problem, unspecified	0.000	0.986	0.013
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.000	0.987	0.013
O43.9 Placental disorder, unspecified	0.000	0.987	0.013
O33.9 Maternal care for disproportion, unspecified	0.000	0.987	0.013
O46.9 Antepartum haemorrhage, unspecified	0.000	0.987	0.013
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.987	0.012
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.987	0.012
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.987	0.012
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.987	0.012
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.987	0.012
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.987	0.012
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.988	0.012
O34.4 Maternal care for other abnormalities of cervix	0.000	0.988	0.012
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.989	0.011
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.000	0.989	0.011
O72.1 Other immediate postpartum haemorrhage	0.000	0.990	0.010
O46.8 Other antepartum haemorrhage	0.000	0.991	0.009
O30.0 Twin pregnancy	0.000	0.991	0.009
T90.4 Sequelae of injury of eye and orbit	0.008	0.992	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.992	0.008
Z00.8 Other general examinations	0.000	0.992	0.008
Z00.3 Examination for adolescent development state	0.000	0.992	0.008
Z00.2 Examination for period of rapid growth in childhood	0.000	0.992	0.008
Z00.1 Routine child health examination	0.000	0.992	0.008
Z00.4 General psychiatric examination, not elsewhere classified	0.000	0.992	0.008
T90.9 Sequelae of unspecified injury of head	0.008	0.992	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.000	0.992	0.008
T90 Sequelae of injuries of head	0.007	0.993	0.000
S82.50 Fracture of medial malleolus (closed)	0.007	0.993	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.006	0.993	0.000
Z71.8 Other specified counselling	0.006	0.994	0.000
D59.1 Other autoimmune haemolytic anaemias	0.006	0.994	0.000
T90.0 Sequelae of superficial injury of head	0.006	0.994	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.001	0.994	0.005
U89.8 Agent resistant to other single specified antibiotic	0.006	0.994	0.000
Z00.5 Examination of potential donor of organ and tissue	0.000	0.994	0.006
T90.3 Sequelae of injury of cranial nerves	0.005	0.994	0.000
O72 Postpartum haemorrhage	0.000	0.994	0.006
T90.1 Sequelae of open wound of head	0.005	0.995	0.000
T90.5 Sequelae of intracranial injury	0.005	0.995	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.995	0.005
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.995	0.005
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.995	0.005
T90.8 Sequelae of other specified injuries of head	0.005	0.995	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.005	0.995	0.000
D68.9 Coagulation defect, unspecified	0.000	0.995	0.005
L40.0 Psoriasis vulgaris	0.005	0.995	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.000	0.995	0.005
D59 Acquired haemolytic anaemia	0.004	0.996	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.004	0.996	0.000
O72.0 Third-stage haemorrhage	0.000	0.996	0.004
O72.3 Postpartum coagulation defects	0.000	0.996	0.004
U89 Agent resistant to other and unspecified antibiotics	0.004	0.996	0.000
C16 Malignant neoplasm of stomach	0.004	0.996	0.000
C16.0 Cardia	0.004	0.996	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.004	0.996	0.000
K22.9 Disease of oesophagus, unspecified	0.000	0.996	0.004
C16.9 Stomach, unspecified	0.004	0.996	0.000
C16.3 Pyloric antrum	0.004	0.996	0.000
C16.2 Body of stomach	0.004	0.996	0.000
C16.4 Pylorus	0.004	0.996	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.996	0.004
T94.1 Sequelae of injuries, not specified by body region	0.004	0.996	0.000
C84.0 Mycosis fungoides	0.003	0.996	0.000
G58.8 Other specified mononeuropathies	0.000	0.997	0.003
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.997	0.003
C16.5 Lesser curvature of stomach, unspecified	0.003	0.997	0.000
D59.8 Other acquired haemolytic anaemias	0.003	0.997	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.003	0.997	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.003	0.997	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.003	0.997	0.000
D59.3 Haemolytic-uraemic syndrome	0.003	0.997	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.003	0.997	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.003	0.997	0.000
E83.5 Disorders of calcium metabolism	0.003	0.997	0.000
C84.5 Other and unspecified T-cell lymphomas	0.003	0.997	0.000
C16.6 Greater curvature of stomach, unspecified	0.003	0.997	0.000
C16.8 Overlapping lesion of stomach	0.003	0.997	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.003	0.997	0.000
U89.9 Agent resistant to unspecified antibiotic	0.003	0.997	0.000
S02.00 Fracture of vault of skull (closed)	0.003	0.997	0.000
S82.5 Fracture of medial malleolus	0.003	0.997	0.000
C10.9 Oropharynx, unspecified	0.003	0.997	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.003	0.997	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.003	0.997	0.000
C84.4 Peripheral T-cell lymphoma	0.003	0.997	0.000
T93.2 Sequelae of other fractures of lower limb	0.003	0.997	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.997	0.003
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.003	0.997	0.000
G63.2 Diabetic polyneuropathy	0.000	0.997	0.003
T93 Sequelae of injuries of lower limb	0.003	0.997	0.000
U88 Agent resistant to multiple antibiotics	0.003	0.997	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.003	0.997	0.000
T93.1 Sequelae of fracture of femur	0.003	0.997	0.000
C77.0 Lymph nodes of head, face and neck	0.003	0.997	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.997	0.003
C16.1 Fundus of stomach	0.002	0.997	0.000
S82.51 Fracture of medial malleolus (open)	0.002	0.997	0.000
M34.9 Systemic sclerosis, unspecified	0.000	0.997	0.003
T93.0 Sequelae of open wound of lower limb	0.002	0.997	0.000
M34.1 CR(E)ST syndrome	0.000	0.997	0.002
N85.9 Noninflammatory disorder of uterus, unspecified	0.003	0.997	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.002	0.998	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.002	0.998	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.002	0.998	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.002	0.998	0.000
C84.3 Lymphoepithelioid lymphoma	0.002	0.998	0.000
C84.2 T-zone lymphoma	0.002	0.998	0.000
C84.1 Sezary's diease	0.002	0.998	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.002	0.998	0.000
S02.0 Fracture of vault of skull	0.002	0.998	0.000
E83 Disorders of mineral metabolism	0.002	0.998	0.000
U84 Resistance to other antimicrobial drugs	0.002	0.998	0.000
U83 Resistance to other antibiotics	0.002	0.998	0.000
U82 Resistance to betalactam antibiotics	0.002	0.998	0.000
U85 Resistance to antineoplastic drugs	0.002	0.998	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
E83.4 Disorders of magnesium metabolism	0.002	0.998	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.002	0.998	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.002	0.998	0.000
J32.0 Chronic maxillary sinusitis	0.002	0.998	0.000
S00-S09 Injuries to the head	0.002	0.998	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.002	0.998	0.000
T98 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
T95 Sequelae of burns, corrosions and frostbite	0.002	0.998	0.000
S05.1 Contusion of eyeball and orbital tissues	0.002	0.998	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
E83.1 Disorders of iron metabolism	0.002	0.998	0.000
S30.2 Contusion of external genital organs	0.002	0.998	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.002	0.998	0.000
R44.1 Visual hallucinations	0.000	0.998	0.002
D55-D59 Haemolytic anaemias	0.002	0.998	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.998	0.002
E83.9 Disorder of mineral metabolism, unspecified	0.002	0.998	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.998	0.002
N87.1 Moderate cervical dysplasia	0.000	0.998	0.002
Y85.0 Sequelae of motor-vehicle accident	0.002	0.998	0.000
D58.2 Other haemoglobinopathies	0.002	0.998	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
U81.0 Vancomycin resistant agent	0.002	0.998	0.000
S02.01 Fracture of vault of skull (open)	0.002	0.998	0.000
E83.8 Other disorders of mineral metabolism	0.002	0.998	0.000
E83.2 Disorders of zinc metabolism	0.002	0.998	0.000
E83.0 Disorders of copper metabolism	0.002	0.998	0.000
U82.9 Resistance to betalactam antibiotics, unspecified	0.002	0.998	0.000
U82.8 Resistance to other betalactam antibiotics	0.002	0.998	0.000
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.002	0.998	0.000
U82.1 Resistance to methicillin	0.002	0.998	0.000
U82.0 Resistance to penicillin	0.002	0.998	0.000
U83.9 Resistance to unspecified antibiotic	0.002	0.998	0.000
U83.8 Resistance to other single specified antibiotic	0.002	0.998	0.000
U83.7 Resistance to multiple antibiotics	0.002	0.998	0.000
U83.2 Resistance to quinolones	0.002	0.998	0.000
U83.1 Resistance to other vancomycin related antibiotics	0.002	0.998	0.000
U83.0 Resistance to vancomycin	0.002	0.998	0.000
U84.9 Resistance to unspecified antimicrobial drugs	0.002	0.998	0.000
U84.8 Resistance to other specified antimicrobial drug	0.002	0.998	0.000
U84.7 Resistance to multiple antimicrobial drugs	0.002	0.998	0.000
U84.3 Resistance to tuberculostatic drug(s)	0.002	0.998	0.000
U84.2 Resistance to antiviral drug(s)	0.002	0.998	0.000
U84.1 Resistance to antifungal drug(s)	0.002	0.998	0.000
U84.0 Resistance to antiparasitic drug(s)	0.002	0.998	0.000
Z03.1 Observation for suspected malignant neoplasm	0.000	0.998	0.002
C10 Malignant neoplasm of oropharynx	0.002	0.998	0.000
G44.2 Tension-type headache	0.000	0.998	0.002
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
M25.50 Pain in joint (Multiple sites)	0.002	0.998	0.000
J95.0 Tracheostomy malfunction	0.002	0.998	0.000
S05 Injury of eye and orbit	0.002	0.998	0.000
S72.30 Fracture of shaft of femur (closed)	0.002	0.998	0.000
D26.0 Cervix uteri	0.000	0.998	0.002
M34 Systemic sclerosis	0.000	0.998	0.002
E83.3 Disorders of phosphorus metabolism	0.002	0.998	0.000
M47.9 Spondylosis, unspecified	0.000	0.998	0.002
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.002	0.998	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.002	0.998	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.002	0.998	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.002	0.998	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.002	0.998	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.002	0.998	0.000
T98.2 Sequelae of certain early complications of trauma	0.002	0.998	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.002	0.998	0.000
Z45.8 Adjustment and management of other implanted devices	0.002	0.998	0.000
S08 Traumatic amputation of part of head	0.002	0.998	0.000
S07 Crushing injury of head	0.002	0.998	0.000
S04 Injury of cranial nerves	0.002	0.998	0.000
Z46.8 Fitting and adjustment of other specified devices	0.002	0.998	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.002	0.998	0.000
D26.1 Corpus uteri	0.000	0.998	0.002
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.998	0.002
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.002	0.998	0.000
S02 Fracture of skull and facial bones	0.002	0.998	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.998	0.002
D57 Sickle-cell disorders	0.002	0.998	0.000
D55 Anaemia due to enzyme disorders	0.002	0.998	0.000
S82.60 Fracture of lateral malleolus (closed)	0.002	0.998	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.002	0.998	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.002	0.998	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.002	0.998	0.000
D58.1 Hereditary elliptocytosis	0.002	0.998	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.002	0.998	0.000
E46 Unspecified protein-energy malnutrition	0.002	0.998	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.001	0.998	0.000
C10.8 Overlapping lesion of oropharynx	0.002	0.998	0.000
C10.4 Branchial cleft	0.002	0.998	0.000
C10.3 Posterior wall of oropharynx	0.002	0.998	0.000
C10.2 Lateral wall of oropharynx	0.002	0.998	0.000
C10.1 Anterior surface of epiglottis	0.002	0.998	0.000
C10.0 Vallecula	0.002	0.998	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.002	0.998	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.002	0.998	0.000
K22.7 Barrett's oesophagus	0.000	0.998	0.002
N48.4 Impotence of organic origin	0.002	0.998	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.998	0.002
D56 Thalassaemia	0.001	0.998	0.000
G50.0 Trigeminal neuralgia	0.002	0.998	0.000
S02.1 Fracture of base of skull	0.002	0.998	0.000
D26.9 Uterus, unspecified	0.000	0.998	0.002
D58.0 Hereditary spherocytosis	0.001	0.998	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
S02.6 Fracture of mandible	0.002	0.998	0.000
S05.7 Avulsion of eye	0.001	0.998	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.001	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.002	0.998	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.998	0.001
M34.0 Progressive systemic sclerosis	0.000	0.998	0.001
Q82.8 Other specified congenital malformations of skin	0.000	0.998	0.002
S04.9 Injury of unspecified cranial nerve	0.001	0.998	0.000
S04.8 Injury of other cranial nerves	0.001	0.998	0.000
S04.7 Injury of accessory nerve	0.001	0.998	0.000
S04.6 Injury of acoustic nerve	0.001	0.998	0.000
S04.5 Injury of facial nerve	0.001	0.998	0.000
S04.4 Injury of abducent nerve	0.001	0.998	0.000
S04.3 Injury of trigeminal nerve	0.001	0.998	0.000
S04.2 Injury of trochlear nerve	0.001	0.998	0.000
S04.1 Injury of oculomotor nerve	0.001	0.998	0.000
S04.0 Injury of optic nerve and pathways	0.001	0.998	0.000
S05.9 Injury of eye and orbit, part unspecified	0.002	0.998	0.000
S07.9 Crushing injury of head, part unspecified	0.001	0.998	0.000
S07.8 Crushing injury of other parts of head	0.001	0.998	0.000
S07.1 Crushing injury of skull	0.001	0.998	0.000
S07.0 Crushing injury of face	0.001	0.998	0.000
S08.9 Traumatic amputation of unspecified part of head	0.001	0.998	0.000
S08.8 Traumatic amputation of other parts of head	0.001	0.998	0.000
S08.1 Traumatic amputation of ear	0.001	0.998	0.000
S08.0 Avulsion of scalp	0.001	0.998	0.000
Z39.1 Care and examination of lactating mother	0.000	0.998	0.002
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.000	0.998	0.001
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.001
T93.8 Sequelae of other specified injuries of lower limb	0.001	0.998	0.000
Z91.7 Personal history of female genital mutilation	0.001	0.998	0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.001	0.998	0.000
Z91.3 Personal history of unhealthy sleep-wake schedule	0.001	0.998	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.998	0.002
Z91.2 Personal history of poor personal hygiene	0.001	0.998	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.000	0.998	0.001
D68.1 Hereditary factor XI deficiency	0.000	0.998	0.002
C01 Malignant neoplasm of base of tongue	0.002	0.998	0.000
D26 Other benign neoplasms of uterus	0.000	0.998	0.002
D55.9 Anaemia due to enzyme disorder, unspecified	0.001	0.998	0.000
D55.8 Other anaemias due to enzyme disorders	0.001	0.998	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.001	0.998	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.001	0.998	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.001	0.998	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.001	0.998	0.000
D57.8 Other sickle-cell disorders	0.001	0.998	0.000
D57.3 Sickle-cell trait	0.001	0.998	0.000
D57.2 Double heterozygous sickling disorders	0.001	0.998	0.000
D57.1 Sickle-cell anaemia without crisis	0.001	0.998	0.000
D57.0 Sickle-cell anaemia with crisis	0.001	0.998	0.000
G58 Other mononeuropathies	0.000	0.998	0.002
D23.9 Skin, unspecified	0.002	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.001	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.002	0.998	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.001	0.998	0.000
S02.8 Fractures of other skull and facial bones	0.001	0.998	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.001	0.998	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.001	0.998	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.998	0.001
D56.1 Beta thalassaemia	0.001	0.998	0.000
H83.0 Labyrinthitis	0.002	0.998	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.001	0.998	0.000
S02.60 Fracture of mandible (closed)	0.001	0.998	0.000
S02.3 Fracture of orbital floor	0.001	0.998	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.001	0.998	0.000
S03.4 Sprain and strain of jaw	0.001	0.998	0.000
S03.3 Dislocation of other and unspecified parts of head	0.001	0.998	0.000
S03.1 Dislocation of septal cartilage of nose	0.001	0.998	0.000
S03.0 Dislocation of jaw	0.001	0.998	0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.001	0.998	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.000	0.999	0.001
D56.9 Thalassaemia, unspecified	0.001	0.999	0.000
D56.8 Other thalassaemias	0.001	0.999	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.001	0.999	0.000
D56.2 Delta-beta thalassaemia	0.001	0.999	0.000
D56.0 Alpha thalassaemia	0.001	0.999	0.000
T43.2 Other and unspecified antidepressants	0.001	0.999	0.000
S02.61 Fracture of mandible (open)	0.001	0.999	0.000
D30.3 Bladder	0.001	0.999	0.000
M34.8 Other forms of systemic sclerosis	0.000	0.999	0.001
D04.6 Skin of upper limb, including shoulder	0.000	0.999	0.001
R57.2 Septic shock	0.001	0.999	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.001	0.999	0.000
Z45.2 Adjustment and management of vascular access device	0.001	0.999	0.000
Z45 Adjustment and management of implanted device	0.001	0.999	0.000
S02.11 Fracture of base of skull (open)	0.001	0.999	0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.000	0.999	0.001
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.999	0.001
D26.7 Other parts of uterus	0.000	0.999	0.001
H11.4 Other conjunctival vascular disorders and cysts	0.001	0.999	0.000
Z91.6 Personal history of other physical trauma	0.001	0.999	0.000
D68 Other coagulation defects	0.000	0.999	0.001
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.999	0.001
K40 Inguinal hernia	0.000	0.999	0.001
S02.71 Multiple fractures involving skull and facial bones (open)	0.001	0.999	0.000
S30.1 Contusion of abdominal wall	0.001	0.999	0.000
S02.81 Fractures of other skull and facial bones (open)	0.001	0.999	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.001	0.999	0.000
F45.8 Other somatoform disorders	0.001	0.999	0.000
G58.7 Mononeuritis multiplex	0.000	0.999	0.001
G58.0 Intercostal neuropathy	0.000	0.999	0.001
S05.8 Other injuries of eye and orbit	0.001	0.999	0.000
D24 Benign neoplasm of breast	0.001	0.999	0.000
T91 Sequelae of injuries of neck and trunk	0.001	0.999	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.001	0.999	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.001	0.999	0.000
Z49.0 Preparatory care for dialysis	0.001	0.999	0.000
Z96.0 Presence of urogenital implants	0.001	0.999	0.000
S02.31 Fracture of orbital floor (open)	0.001	0.999	0.000
C49.5 Connective and soft tissue of pelvis	0.000	0.999	0.001
F45.3 Somatoform autonomic dysfunction	0.001	0.999	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.001	0.999	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.001	0.999	0.000
T42.3 Barbiturates	0.001	0.999	0.000
T42.2 Succinimides and oxazolidinediones	0.001	0.999	0.000
U81.8 Agent resistant to other vancomycin-related antibiotic	0.001	0.999	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.001	0.999	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.999	0.001
I46.9 Cardiac arrest, unspecified	0.000	0.999	0.001
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.001	0.999	0.000
C07 Malignant neoplasm of parotid gland	0.001	0.999	0.000
A63.0 Anogenital (venereal) warts	0.000	0.999	0.001
S03.2 Dislocation of tooth	0.001	0.999	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.001	0.999	0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.001	0.999	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.001	0.999	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.001	0.999	0.000
S02.5 Fracture of tooth	0.001	0.999	0.000
S02.2 Fracture of nasal bones	0.001	0.999	0.001
S09.8 Other specified injuries of head	0.001	0.999	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.001	0.999	0.000
Z45.9 Adjustment and management of unspecified implanted device	0.001	0.999	0.000
Z46.7 Fitting and adjustment of orthopaedic device	0.001	0.999	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.001	0.999	0.000
B37.8 Candidiasis of other sites	0.000	0.999	0.001
B37.3 Candidiasis of vulva and vagina	0.000	0.999	0.001
D56.3 Thalassaemia trait	0.001	0.999	0.001
G58.9 Mononeuropathy, unspecified	0.000	0.999	0.001
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.999	0.001
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.999	0.001
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.999	0.001
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.999	0.001
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.999	0.001
G63.1 Polyneuropathy in neoplastic disease	0.000	0.999	0.001
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
I24.9 Acute ischaemic heart disease, unspecified	0.001	0.999	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.000	0.999	0.001
K40.1 Bilateral inguinal hernia, with gangrene	0.000	0.999	0.001
T42.0 Hydantoin derivatives	0.001	0.999	0.000
S82.61 Fracture of lateral malleolus (open)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations