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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17522649
log Bayes Factor = 26.3622
Chromosome 15   position 93,084,746  (GRCh37) Explore rs17522649 on Ensembl!
Variant rs17522649 is part of Cluster X0040

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
K70-K77 Diseases of liver
0.998 0.002 0.000
N19 Unspecified renal failure
0.998 0.002 0.000
N40-N51 Diseases of male genital organs
0.994 0.006 0.000
K70 Alcoholic liver disease
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
J40-J47 Chronic lower respiratory diseases
0.993 0.007 0.000
K55-K64 Other diseases of intestines
0.992 0.008 0.000
N17 Acute renal failure
0.988 0.012 0.000
Chapter VI Diseases of the nervous system
0.988 0.012 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.987 0.013 0.000
E70-E90 Metabolic disorders
0.984 0.016 0.000
S60-S69 Injuries to the wrist and hand
0.983 0.017 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.982 0.018 0.000
Chapter VII Diseases of the eye and adnexa
0.981 0.019 0.000
N17.9 Acute renal failure, unspecified
0.980 0.020 0.000
I50 Heart failure
0.977 0.023 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.974 0.026 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.973 0.027 0.000
Chapter V Mental and behavioural disorders
0.972 0.028 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.968 0.032 0.000
K57 Diverticular disease of intestine
0.967 0.033 0.000
N18 Chronic renal failure
0.961 0.039 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.956 0.044 0.000
G30-G32 Other degenerative diseases of the nervous system
0.956 0.044 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.951 0.049 0.000
S00-S09 Injuries to the head
0.950 0.050 0.000
I50.0 Congestive heart failure
0.949 0.051 0.000
J44 Other chronic obstructive pulmonary disease
0.949 0.051 0.000
N41 Inflammatory diseases of prostate
0.945 0.055 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.944 0.056 0.000
J43 Emphysema
0.941 0.059 0.000
K20 Oesophagitis
0.939 0.061 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.938 0.062 0.000
K70.9 Alcoholic liver disease, unspecified
0.937 0.063 0.000
H30-H36 Disorders of choroid and retina
0.935 0.065 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.935 0.065 0.000
N50 Other disorders of male genital organs
0.932 0.068 0.000
I47 Paroxysmal tachycardia
0.931 0.069 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.931 0.069 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.930 0.070 0.000
S61 Open wound of wrist and hand
0.930 0.070 0.000
Chapter XXI Factors influencing health status and contact with health services
0.929 0.071 0.000
J09-J18 Influenza and pneumonia
0.927 0.073 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.927 0.073 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.926 0.074 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.926 0.074 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.926 0.074 0.000
E20-E35 Disorders of other endocrine glands
0.925 0.075 0.000
E86 Volume depletion
0.924 0.076 0.000
J95-J99 Other diseases of the respiratory system
0.923 0.077 0.000
K70.3 Alcoholic cirrhosis of liver
0.922 0.078 0.000
I44 Atrioventricular and left bundle-branch block
0.922 0.078 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.922 0.078 0.000
A30-A49 Other bacterial diseases
0.916 0.084 0.000
Z96 Presence of other functional implants
0.916 0.084 0.000
I34 Nonrheumatic mitral valve disorders
0.916 0.084 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.915 0.085 0.000
N10-N16 Renal tubulo-interstitial diseases
0.912 0.088 0.000
R26 Abnormalities of gait and mobility
0.908 0.092 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.908 0.092 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.908 0.092 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.908 0.092 0.000
Z96.8 Presence of other specified functional implants
0.907 0.093 0.000
E83 Disorders of mineral metabolism
0.906 0.094 0.000
J43.9 Emphysema, unspecified
0.904 0.096 0.000
N00-N08 Glomerular diseases
0.903 0.097 0.000
S62 Fracture at wrist and hand level
0.900 0.100 0.000
K22 Other diseases of oesophagus
0.898 0.102 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.895 0.105 0.000
N50.8 Other specified disorders of male genital organs
0.895 0.105 0.000
K56.2 Volvulus
0.891 0.109 0.000
I45 Other conduction disorders
0.890 0.110 0.000
R47-R49 Symptoms and signs involving speech and voice
0.888 0.112 0.000
R79 Other abnormal findings of blood chemistry
0.887 0.113 0.000
S80-S89 Injuries to the knee and lower leg
0.887 0.113 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.882 0.118 0.000
N42 Other disorders of prostate
0.882 0.118 0.000
K50-K52 Noninfective enteritis and colitis
0.881 0.119 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.879 0.121 0.000
J98 Other respiratory disorders
0.876 0.124 0.000
N41.1 Chronic prostatitis
0.875 0.125 0.000
R94 Abnormal results of function studies
0.875 0.125 0.000
E16 Other disorders of pancreatic internal secretion
0.874 0.126 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.873 0.126 0.000
N18.0 End-stage renal disease
0.872 0.128 0.000
S90-S99 Injuries to the ankle and foot
0.872 0.128 0.000
H35 Other retinal disorders
0.871 0.129 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.868 0.132 0.000
R73 Elevated blood glucose level
0.867 0.133 0.000
I44.0 Atrioventricular block, first degree
0.866 0.134 0.000
K74 Fibrosis and cirrhosis of liver
0.862 0.138 0.000
K70.1 Alcoholic hepatitis
0.861 0.139 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.859 0.141 0.000
R25 Abnormal involuntary movements
0.858 0.142 0.000
A00-A09 Intestinal infectious diseases
0.856 0.144 0.000
J00-J06 Acute upper respiratory infections
0.856 0.144 0.000
N48 Other disorders of penis
0.855 0.145 0.000
F10.2 Dependence syndrome
0.852 0.148 0.000
H53-H54 Visual disturbances and blindness
0.852 0.148 0.000
K62 Other diseases of anus and rectum
0.851 0.149 0.000
S61.0 Open wound of finger(s) without damage to nail
0.850 0.150 0.000
N18.5 Chronic kidney disease, stage 5
0.850 0.150 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.850 0.150 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.848 0.152 0.000
B25-B34 Other viral diseases
0.846 0.154 0.000
Z96.0 Presence of urogenital implants
0.845 0.155 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.844 0.156 0.000
I50.9 Heart failure, unspecified
0.842 0.158 0.000
B95-B98 Bacterial, viral and other infectious agents
0.842 0.158 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.842 0.158 0.000
Z98 Other postsurgical states
0.841 0.159 0.000
E87.5 Hyperkalaemia
0.840 0.160 0.000
B50-B64 Protozoal diseases
0.839 0.161 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.838 0.162 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.838 0.162 0.000
E16.2 Hypoglycaemia, unspecified
0.837 0.163 0.000
A41 Other septicaemia
0.836 0.164 0.000
S09 Other and unspecified injuries of head
0.835 0.165 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.833 0.167 0.000
K72 Hepatic failure, not elsewhere classified
0.832 0.168 0.000
J17 Pneumonia in diseases classified elsewhere
0.831 0.168 0.000
I42 Cardiomyopathy
0.831 0.169 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.829 0.171 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.828 0.172 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.827 0.173 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.827 0.173 0.000
I05-I09 Chronic rheumatic heart diseases
0.825 0.175 0.000
I47.1 Supraventricular tachycardia
0.825 0.175 0.000
K62.0 Anal polyp
0.825 0.175 0.000
N42.8 Other specified disorders of prostate
0.823 0.177 0.000
K70.4 Alcoholic hepatic failure
0.822 0.178 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.821 0.179 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.821 0.179 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.820 0.180 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.820 0.180 0.000
H52 Disorders of refraction and accommodation
0.819 0.181 0.000
G90-G99 Other disorders of the nervous system
0.819 0.181 0.000
J90-J94 Other diseases of pleura
0.818 0.182 0.000
S70-S79 Injuries to the hip and thigh
0.818 0.182 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.817 0.183 0.000
J42 Unspecified chronic bronchitis
0.815 0.185 0.000
N25-N29 Other disorders of kidney and ureter
0.813 0.187 0.000
K56.1 Intussusception
0.813 0.187 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.813 0.187 0.000
E10-E14 Diabetes mellitus
0.810 0.190 0.000
K22.2 Oesophageal obstruction
0.809 0.191 0.000
J60-J70 Lung diseases due to external agents
0.807 0.193 0.000
E87.6 Hypokalaemia
0.805 0.195 0.000
J98.1 Pulmonary collapse
0.805 0.195 0.000
K22.1 Ulcer of oesophagus
0.805 0.195 0.000
I34.0 Mitral (valve) insufficiency
0.803 0.197 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.802 0.198 0.000
K55 Vascular disorders of intestine
0.802 0.198 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.801 0.199 0.000
S81 Open wound of lower leg
0.798 0.202 0.000
A41.9 Septicaemia, unspecified
0.797 0.203 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.795 0.205 0.000
H35.8 Other specified retinal disorders
0.795 0.205 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.794 0.206 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.794 0.206 0.000
Z95.0 Presence of cardiac pacemaker
0.793 0.207 0.000
N13 Obstructive and reflux uropathy
0.791 0.209 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.791 0.209 0.000
I95 Hypotension
0.790 0.210 0.000
T81 Complications of procedures, not elsewhere classified
0.790 0.210 0.000
I36 Nonrheumatic tricuspid valve disorders
0.790 0.210 0.000
K76 Other diseases of liver
0.789 0.210 0.000
J47 Bronchiectasis
0.789 0.210 0.000
K52 Other non-infective gastro-enteritis and colitis
0.788 0.212 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.788 0.212 0.000
S62.6 Fracture of other finger
0.788 0.212 0.000
R94.5 Abnormal results of liver function studies
0.788 0.212 0.000
K27 Peptic ulcer, site unspecified
0.787 0.213 0.000
G31.2 Degeneration of nervous system due to alcohol
0.787 0.213 0.000
K56.7 Ileus, unspecified
0.786 0.214 0.000
N03 Chronic nephritic syndrome
0.786 0.214 0.000
F03 Unspecified dementia
0.785 0.215 0.000
F01 Vascular dementia
0.785 0.215 0.000
I30 Acute pericarditis
0.784 0.216 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.784 0.216 0.000
R76 Other abnormal immunological findings in serum
0.783 0.217 0.000
R73.9 Hyperglycaemia, unspecified
0.783 0.217 0.000
S01 Open wound of head
0.781 0.219 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.780 0.220 0.000
N18.2 Chronic kidney disease, stage 2
0.780 0.220 0.000
I46 Cardiac arrest
0.779 0.221 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.779 0.221 0.000
N41.0 Acute prostatitis
0.779 0.221 0.000
I34.1 Mitral (valve) prolapse
0.779 0.221 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.778 0.222 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.778 0.222 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.776 0.224 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.775 0.225 0.000
H53 Visual disturbances
0.775 0.225 0.000
G56 Mononeuropathies of upper limb
0.771 0.228 0.000
A08 Viral and other specified intestinal infections
0.771 0.229 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.769 0.231 0.000
I45.1 Other and unspecified right bundle-branch block
0.769 0.231 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.768 0.232 0.000
E27 Other disorders of adrenal gland
0.768 0.232 0.000
K31 Other diseases of stomach and duodenum
0.767 0.233 0.000
S10-S19 Injuries to the neck
0.766 0.234 0.000
S06 Intracranial injury
0.766 0.234 0.000
H31 Other disorders of choroid
0.766 0.234 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.765 0.235 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.764 0.236 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.763 0.237 0.000
S62.5 Fracture of thumb
0.763 0.237 0.000
K65-K67 Diseases of peritoneum
0.761 0.238 0.000
Chapter XXII Codes for special purposes
0.761 0.239 0.000
E22 Hyperfunction of pituitary gland
0.759 0.241 0.000
I85 Oesophageal varices
0.759 0.241 0.000
J84 Other interstitial pulmonary diseases
0.756 0.244 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.755 0.245 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.754 0.246 0.000
F10.3 Withdrawal state
0.754 0.246 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.754 0.246 0.000
S09.9 Unspecified injury of head
0.753 0.247 0.000
H36 Retinal disorders in diseases classified elsewhere
0.750 0.250 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.750 0.250 0.000
T93 Sequelae of injuries of lower limb
0.749 0.251 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.749 0.251 0.000
E83.4 Disorders of magnesium metabolism
0.748 0.251 0.000
R47 Speech disturbances, not elsewhere classified
0.748 0.252 0.000
H52.1 Myopia
0.748 0.252 0.000
G30 Alzheimer's disease
0.748 0.252 0.000
A80-A89 Viral infections of the central nervous system
0.748 0.252 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.747 0.253 0.000
Z98.0 Intestinal bypass and anastomosis status
0.746 0.254 0.000
K62.9 Disease of anus and rectum, unspecified
0.746 0.254 0.000
K75 Other inflammatory liver diseases
0.745 0.255 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.745 0.255 0.000
F60-F69 Disorders of adult personality and behaviour
0.745 0.255 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.744 0.256 0.000
R49 Voice disturbances
0.744 0.256 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.744 0.256 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.744 0.256 0.000
S60 Superficial injury of wrist and hand
0.742 0.257 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.743 0.257 0.000
I44.2 Atrioventricular block, complete
0.742 0.258 0.000
T86 Failure and rejection of transplanted organs and tissues
0.742 0.258 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.741 0.258 0.000
K50 Crohn's disease [regional enteritis]
0.741 0.259 0.000
B34 Viral infection of unspecified site
0.741 0.259 0.000
Z95.3 Presence of xenogenic heart valve
0.740 0.260 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.740 0.260 0.000
R40 Somnolence, stupor and coma
0.739 0.261 0.000
T79-T79 Certain early complications of trauma
0.739 0.261 0.000
S05 Injury of eye and orbit
0.738 0.262 0.000
N99-N99 Other disorders of the genitourinary system
0.737 0.263 0.000
T98 Sequelae of other and unspecified effects of external causes
0.737 0.263 0.000
J02 Acute pharyngitis
0.736 0.264 0.000
S92 Fracture of foot, except ankle
0.735 0.265 0.000
K56.0 Paralytic ileus
0.735 0.265 0.000
R25.1 Tremor, unspecified
0.734 0.266 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.733 0.267 0.000
E83.1 Disorders of iron metabolism
0.732 0.268 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.732 0.268 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.732 0.268 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.732 0.268 0.000
B59 Pneumocystosis
0.729 0.271 0.000
E83.5 Disorders of calcium metabolism
0.729 0.271 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.728 0.271 0.000
R29.6 Tendency to fall, not elsewhere classified
0.728 0.272 0.000
R79.0 Abnormal level of blood mineral
0.728 0.272 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.728 0.272 0.000
J98.9 Respiratory disorder, unspecified
0.728 0.272 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.727 0.273 0.000
G31.8 Other specified degenerative diseases of nervous system
0.727 0.273 0.000
J17.3 Pneumonia in parasitic diseases
0.725 0.275 0.000
E40-E46 Malnutrition
0.725 0.275 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.725 0.275 0.000
Z96.7 Presence of other bone and tendon implants
0.724 0.276 0.000
E26 Hyperaldosteronism
0.723 0.277 0.000
S64 Injury of nerves at wrist and hand level
0.723 0.277 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.722 0.278 0.000
H33 Retinal detachments and breaks
0.721 0.279 0.000
Z87 Personal history of other diseases and conditions
0.721 0.279 0.000
K76.6 Portal hypertension
0.718 0.282 0.000
E28 Ovarian dysfunction
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I33 Acute and subacute endocarditis
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
K77 Liver disorders in diseases classified elsewhere
0.716 0.284 0.000
K73 Chronic hepatitis, not elsewhere classified
0.716 0.284 0.000
K71 Toxic liver disease
0.716 0.284 0.000
Z95.2 Presence of prosthetic heart valve
0.715 0.285 0.000
J40 Bronchitis, not specified as acute or chronic
0.714 0.286 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.714 0.286 0.000
I47.2 Ventricular tachycardia
0.714 0.286 0.000
K72.9 Hepatic failure, unspecified
0.713 0.287 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.713 0.287 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.713 0.287 0.000
N46 Male infertility
0.713 0.287 0.000
N44 Torsion of testis
0.713 0.287 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.712 0.288 0.000
K70.0 Alcoholic fatty liver
0.712 0.288 0.000
B99-B99 Other infectious diseases
0.712 0.288 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.712 0.288 0.000
B15-B19 Viral hepatitis
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
K90-K93 Other diseases of the digestive system
0.712 0.288 0.000
J41 Simple and mucopurulent chronic bronchitis
0.712 0.288 0.000
J46 Status asthmaticus
0.712 0.288 0.000
E23 Hypofunction and other disorders of pituitary gland
0.711 0.289 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.711 0.289 0.000
A08.4 Viral intestinal infection, unspecified
0.711 0.289 0.000
Z91.5 Personal history of self-harm
0.710 0.290 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.710 0.290 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.710 0.290 0.000
S61.1 Open wound of finger(s) with damage to nail
0.710 0.290 0.000
T91 Sequelae of injuries of neck and trunk
0.710 0.290 0.000
N17.8 Other acute renal failure
0.709 0.291 0.000
N17.2 Acute renal failure with medullary necrosis
0.709 0.291 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.709 0.291 0.000
N17.0 Acute renal failure with tubular necrosis
0.709 0.291 0.000
I85.9 Oesophageal varices without bleeding
0.708 0.292 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.708 0.292 0.000
E83.3 Disorders of phosphorus metabolism
0.708 0.292 0.000
H35.7 Separation of retinal layers
0.708 0.292 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.708 0.292 0.000
K74.6 Other and unspecified cirrhosis of liver
0.707 0.293 0.000
S62.60 Fracture of other finger (closed)
0.707 0.293 0.000
Z89 Acquired absence of limb
0.707 0.293 0.000
A49 Bacterial infection of unspecified site
0.706 0.294 0.000
N18.9 Chronic renal failure, unspecified
0.706 0.294 0.000
J14 Pneumonia due to Haemophilus influenzae
0.706 0.294 0.000
K22.8 Other specified diseases of oesophagus
0.706 0.294 0.000
S20-S29 Injuries to the thorax
0.706 0.294 0.000
E85 Amyloidosis
0.706 0.294 0.000
E84 Cystic fibrosis
0.706 0.294 0.000
E79 Disorders of purine and pyrimidine metabolism
0.706 0.294 0.000
E77 Disorders of glycoprotein metabolism
0.706 0.294 0.000
E76 Disorders of glycosaminoglycan metabolism
0.706 0.294 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.706 0.294 0.000
E74 Other disorders of carbohydrate metabolism
0.706 0.294 0.000
E73 Lactose intolerance
0.706 0.294 0.000
E72 Other disorders of amino-acid metabolism
0.706 0.294 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.706 0.294 0.000
E70 Disorders of aromatic amino-acid metabolism
0.706 0.294 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.706 0.294 0.000
I45.6 Preexcitation syndrome
0.705 0.294 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.705 0.295 0.000
S69 Other and unspecified injuries of wrist and hand
0.705 0.295 0.000
S67 Crushing injury of wrist and hand
0.705 0.295 0.000
S65 Injury of blood vessels at wrist and hand level
0.705 0.295 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.704 0.296 0.000
R77 Other abnormalities of plasma proteins
0.704 0.296 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.704 0.296 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.704 0.296 0.000
R71 Abnormality of red blood cells
0.704 0.296 0.000
I73 Other peripheral vascular diseases
0.704 0.296 0.000
I05 Rheumatic mitral valve diseases
0.703 0.297 0.000
E00-E07 Disorders of thyroid gland
0.702 0.298 0.000
N03.9 Unspecified
0.702 0.298 0.000
Z87.0 Personal history of diseases of the respiratory system
0.702 0.298 0.000
N45 Orchitis and epididymitis
0.702 0.298 0.000
R26.3 Immobility
0.701 0.299 0.000
K31.7 Polyp of stomach and duodenum
0.701 0.299 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.700 0.299 0.000
S02 Fracture of skull and facial bones
0.700 0.300 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.700 0.300 0.000
A46 Erysipelas
0.700 0.300 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.700 0.300 0.000
H55-H59 Other disorders of eye and adnexa
0.699 0.301 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.699 0.301 0.000
K35-K38 Diseases of appendix
0.698 0.302 0.000
S81.0 Open wound of knee
0.698 0.302 0.000
T87 Complications peculiar to reattachment and amputation
0.698 0.302 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.697 0.303 0.000
G56.2 Lesion of ulnar nerve
0.697 0.303 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.697 0.303 0.000
F80-F89 Disorders of psychological development
0.697 0.303 0.000
F70-F79 Mental retardation
0.697 0.303 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.697 0.303 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.697 0.303 0.000
N48.9 Disorder of penis, unspecified
0.697 0.303 0.000
F01.9 Vascular dementia, unspecified
0.697 0.303 0.000
N02 Recurrent and persistent haematuria
0.695 0.305 0.000
K56.3 Gallstone ileus
0.694 0.306 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.694 0.306 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.693 0.307 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.693 0.307 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.693 0.307 0.000
Z83 Family history of other specific disorders
0.692 0.307 0.000
I95.1 Orthostatic hypotension
0.692 0.308 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.692 0.308 0.000
E65-E68 Obesity and other hyperalimentation
0.691 0.309 0.000
I44.1 Atrioventricular block, second degree
0.690 0.310 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.690 0.310 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.690 0.310 0.000
K74.0 Hepatic fibrosis
0.690 0.310 0.000
N18.8 Other chronic renal failure
0.689 0.311 0.000
N18.1 Chronic kidney disease, stage 1
0.689 0.311 0.000
J18 Pneumonia, organism unspecified
0.689 0.311 0.000
K63 Other diseases of intestine
0.689 0.311 0.000
S61.8 Open wound of other parts of wrist and hand
0.688 0.312 0.000
S72 Fracture of femur
0.687 0.313 0.000
S89 Other and unspecified injuries of lower leg
0.686 0.314 0.000
S40-S49 Injuries to the shoulder and upper arm
0.686 0.314 0.000
E29 Testicular dysfunction
0.686 0.314 0.000
S00 Superficial injury of head
0.686 0.314 0.000
K28 Gastrojejunal ulcer
0.685 0.314 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.685 0.314 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.685 0.315 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.685 0.315 0.000
T90 Sequelae of injuries of head
0.685 0.315 0.000
K62.7 Radiation proctitis
0.684 0.315 0.000
R41.0 Disorientation, unspecified
0.684 0.315 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.682 0.318 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.682 0.318 0.000
S01.2 Open wound of nose
0.682 0.318 0.000
G58 Other mononeuropathies
0.682 0.318 0.000
S99 Other and unspecified injuries of ankle and foot
0.682 0.318 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.681 0.319 0.000
I99 Other and unspecified disorders of circulatory system
0.681 0.319 0.000
N05 Unspecified nephritic syndrome
0.681 0.319 0.000
S08 Traumatic amputation of part of head
0.681 0.319 0.000
S07 Crushing injury of head
0.681 0.319 0.000
S04 Injury of cranial nerves
0.681 0.319 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.681 0.319 0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.680 0.320 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.679 0.321 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.679 0.321 0.000
N11 Chronic tubulo-interstitial nephritis
0.678 0.322 0.000
I77 Other disorders of arteries and arterioles
0.678 0.322 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.678 0.322 0.000
N48.8 Other specified disorders of penis
0.678 0.322 0.000
S80 Superficial injury of lower leg
0.677 0.322 0.000
N41.8 Other inflammatory diseases of prostate
0.677 0.322 0.000
N41.3 Prostatocystitis
0.677 0.322 0.000
N41.2 Abscess of prostate
0.677 0.322 0.000
R74 Abnormal serum enzyme levels
0.677 0.323 0.000
E87.7 Fluid overload
0.677 0.323 0.000
H10-H13 Disorders of conjunctiva
0.677 0.323 0.000
Z98.8 Other specified postsurgical states
0.677 0.323 0.000
K61 Abscess of anal and rectal regions
0.677 0.323 0.000
G70-G73 Diseases of myoneural junction and muscle
0.676 0.323 0.000
R02 Gangrene, not elsewhere classified
0.676 0.324 0.000
J43.8 Other emphysema
0.675 0.325 0.000
J43.2 Centrilobular emphysema
0.675 0.325 0.000
J43.1 Panlobular emphysema
0.675 0.325 0.000
J43.0 MacLeod's syndrome
0.675 0.325 0.000
N13.4 Hydroureter
0.674 0.326 0.000
J11 Influenza, virus not identified
0.674 0.326 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.673 0.327 0.000
E87.4 Mixed disorder of acid-base balance
0.673 0.327 0.000
E87.3 Alkalosis
0.673 0.327 0.000
T85.2 Mechanical complication of intraocular lens
0.671 0.329 0.000
J00 Acute nasopharyngitis [common cold]
0.670 0.329 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.670 0.330 0.000
H30 Chorioretinal inflammation
0.670 0.330 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.670 0.330 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.670 0.330 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.670 0.330 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.670 0.330 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.670 0.330 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.670 0.330 0.000
F11 Mental and behavioural disorders due to use of opioids
0.670 0.330 0.000
K50.9 Crohn's disease, unspecified
0.670 0.330 0.000
F10.1 Harmful use
0.670 0.330 0.000
I45.5 Other specified heart block
0.669 0.331 0.000
K55.0 Acute vascular disorders of intestine
0.669 0.331 0.000
J93 Pneumothorax
0.669 0.331 0.000
N18.3 Chronic kidney disease, stage 3
0.668 0.332 0.000
D50-D53 Nutritional anaemias
0.668 0.332 0.000
N50.9 Disorder of male genital organs, unspecified
0.668 0.332 0.000
N50.0 Atrophy of testis
0.668 0.332 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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