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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17592741
log Bayes Factor = 11.219
Chromosome 5   position 153,000,842  (GRCh37) Explore rs17592741 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.993 0.007 0.000
Z92 Personal history of medical treatment
0.989 0.011 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.980 0.020 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.980 0.020 0.000
Chapter XXI Factors influencing health status and contact with health services
0.979 0.021 0.000
Chapter XX External causes of morbidity and mortality
0.979 0.021 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.979 0.021 0.000
I50 Heart failure
0.977 0.023 0.000
Z92.3 Personal history of irradiation
0.975 0.025 0.000
M20-M25 Other joint disorders
0.974 0.026 0.000
Z86 Personal history of certain other diseases
0.973 0.027 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.972 0.028 0.000
Z86.4 Personal history of psychoactive substance abuse
0.967 0.033 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.966 0.034 0.000
M25 Other joint disorders, not elsewhere classified
0.966 0.034 0.000
D60-D64 Aplastic and other anaemias
0.966 0.034 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.962 0.038 0.000
M25.7 Osteophyte
0.960 0.040 0.000
I35 Nonrheumatic aortic valve disorders
0.959 0.041 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.956 0.044 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.955 0.045 0.000
D64 Other anaemias
0.955 0.045 0.000
Chapter I Certain infectious and parasitic diseases
0.951 0.049 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.949 0.051 0.000
I44 Atrioventricular and left bundle-branch block
0.949 0.051 0.000
D64.9 Anaemia, unspecified
0.947 0.053 0.000
I50.1 Left ventricular failure
0.947 0.053 0.000
I60-I69 Cerebrovascular diseases
0.947 0.053 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.946 0.054 0.000
E83 Disorders of mineral metabolism
0.944 0.056 0.000
E87.2 Acidosis
0.940 0.060 0.000
Z97 Presence of other devices
0.935 0.065 0.000
Chapter X Diseases of the respiratory system
0.930 0.070 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.929 0.071 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.927 0.073 0.000
E89.0 Postprocedural hypothyroidism
0.926 0.074 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.923 0.077 0.000
Chapter II Neoplasms
0.922 0.078 0.000
I51 Complications and ill-defined descriptions of heart disease
0.921 0.079 0.000
I20-I25 Ischaemic heart diseases
0.918 0.082 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.910 0.090 0.000
E20-E35 Disorders of other endocrine glands
0.908 0.092 0.000
I69 Sequelae of cerebrovascular disease
0.901 0.099 0.000
I71 Aortic aneurysm and dissection
0.897 0.103 0.000
M24 Other specific joint derangements
0.897 0.103 0.000
A00-A09 Intestinal infectious diseases
0.888 0.112 0.000
I20 Angina pectoris
0.888 0.112 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.888 0.112 0.000
Chapter VIII Diseases of the ear and mastoid process
0.883 0.117 0.000
M65-M68 Disorders of synovium and tendon
0.878 0.122 0.000
I51.9 Heart disease, unspecified
0.877 0.123 0.000
L91 Hypertrophic disorders of skin
0.876 0.124 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.875 0.125 0.000
M25.76 Osteophyte (Lower leg)
0.870 0.130 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.868 0.132 0.000
I20.9 Angina pectoris, unspecified
0.867 0.133 0.000
J95-J99 Other diseases of the respiratory system
0.866 0.134 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.864 0.136 0.000
O32.1 Maternal care for breech presentation
0.864 0.136 0.000
J09-J18 Influenza and pneumonia
0.862 0.138 0.000
M25.77 Osteophyte (Ankle and foot)
0.860 0.140 0.000
B35-B49 Mycoses
0.859 0.141 0.000
I44.7 Left bundle-branch block, unspecified
0.857 0.143 0.000
J00-J06 Acute upper respiratory infections
0.856 0.144 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.855 0.145 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.853 0.147 0.000
Y40 Systemic antibiotics
0.852 0.148 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.852 0.148 0.000
E87.6 Hypokalaemia
0.851 0.149 0.000
W00-W19 Falls
0.850 0.150 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.849 0.151 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.849 0.151 0.000
Chapter VII Diseases of the eye and adnexa
0.847 0.153 0.000
I35.0 Aortic (valve) stenosis
0.846 0.154 0.000
E83.5 Disorders of calcium metabolism
0.842 0.158 0.000
L91.8 Other hypertrophic disorders of skin
0.840 0.160 0.000
M25.74 Osteophyte (Hand)
0.837 0.163 0.000
A04 Other bacterial intestinal infections
0.833 0.167 0.000
E10-E14 Diabetes mellitus
0.830 0.170 0.000
J98 Other respiratory disorders
0.828 0.172 0.000
I22 Subsequent myocardial infarction
0.827 0.173 0.000
H60-H62 Diseases of external ear
0.823 0.177 0.000
Chapter V Mental and behavioural disorders
0.823 0.177 0.000
M31 Other necrotising vasculopathies
0.820 0.180 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.820 0.180 0.000
M15-M19 Arthrosis
0.819 0.181 0.000
D80-D89 Certain disorders involving the immune mechanism
0.819 0.181 0.000
W20-W49 Exposure to inanimate mechanical forces
0.817 0.183 0.000
L20-L30 Dermatitis and eczema
0.815 0.185 0.000
Z97.8 Presence of other specified devices
0.812 0.188 0.000
S00-S09 Injuries to the head
0.812 0.188 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.809 0.191 0.000
J98.1 Pulmonary collapse
0.809 0.191 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.809 0.191 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.808 0.192 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.808 0.192 0.000
I35.9 Aortic valve disorder, unspecified
0.808 0.192 0.000
I38 Endocarditis, valve unspecified
0.807 0.193 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.807 0.193 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.807 0.193 0.000
M21 Other acquired deformities of limbs
0.805 0.195 0.000
E40-E46 Malnutrition
0.804 0.196 0.000
I35.1 Aortic (valve) insufficiency
0.802 0.198 0.000
I49 Other cardiac arrhythmias
0.802 0.198 0.000
Z95.4 Presence of other heart-valve replacement
0.798 0.202 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.797 0.203 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.797 0.203 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.796 0.204 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.796 0.204 0.000
I37 Pulmonary valve disorders
0.796 0.204 0.000
E23 Hypofunction and other disorders of pituitary gland
0.794 0.206 0.000
M24.0 Loose body in joint
0.794 0.206 0.000
M19 Other arthrosis
0.793 0.207 0.000
C64-C68 Malignant neoplasms of urinary tract
0.793 0.207 0.000
M65 Synovitis and tenosynovitis
0.793 0.207 0.000
E83.3 Disorders of phosphorus metabolism
0.792 0.208 0.000
H61 Other disorders of external ear
0.791 0.209 0.000
J18 Pneumonia, organism unspecified
0.790 0.210 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.789 0.211 0.000
M25.4 Effusion of joint
0.789 0.211 0.000
M25.71 Osteophyte (Shoulder region)
0.784 0.216 0.000
S40-S49 Injuries to the shoulder and upper arm
0.782 0.218 0.000
E27 Other disorders of adrenal gland
0.782 0.218 0.000
Y44 Agents primarily affecting blood constituents
0.782 0.218 0.000
W50-W64 Exposure to animate mechanical forces
0.782 0.218 0.000
Z89 Acquired absence of limb
0.780 0.220 0.000
M19.9 Arthrosis, unspecified
0.780 0.220 0.000
I69.3 Sequelae of cerebral infarction
0.780 0.220 0.000
I44.6 Other and unspecified fascicular block
0.780 0.220 0.000
S00 Superficial injury of head
0.779 0.221 0.000
I50.9 Heart failure, unspecified
0.776 0.224 0.000
M25.8 Other specified joint disorders
0.776 0.224 0.000
L81 Other disorders of pigmentation
0.774 0.226 0.000
I44.1 Atrioventricular block, second degree
0.774 0.226 0.000
E83.1 Disorders of iron metabolism
0.773 0.227 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.772 0.228 0.000
J00 Acute nasopharyngitis [common cold]
0.772 0.228 0.000
H90-H95 Other disorders of ear
0.771 0.229 0.000
B15-B19 Viral hepatitis
0.770 0.230 0.000
I72 Other aneurysm
0.766 0.234 0.000
O41 Other disorders of amniotic fluid and membranes
0.764 0.235 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.764 0.236 0.000
C80 Malignant neoplasm without specification of site
0.764 0.236 0.000
I44.0 Atrioventricular block, first degree
0.763 0.237 0.000
I50.0 Congestive heart failure
0.763 0.237 0.000
Y57 Other and unspecified drugs and medicaments
0.759 0.241 0.000
L85 Other epidermal thickening
0.759 0.241 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.758 0.242 0.000
Chapter XXII Codes for special purposes
0.757 0.243 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.756 0.244 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.755 0.245 0.000
L27 Dermatitis due to substances taken internally
0.755 0.245 0.000
E10 Insulin-dependent diabetes mellitus
0.750 0.250 0.000
Z97.0 Presence of artificial eye
0.750 0.250 0.000
I36 Nonrheumatic tricuspid valve disorders
0.749 0.251 0.000
E50-E64 Other nutritional deficiencies
0.748 0.252 0.000
I46 Cardiac arrest
0.748 0.252 0.000
Y48 Anaesthetics and therapeutic gases
0.747 0.253 0.000
Z86.7 Personal history of diseases of the circulatory system
0.745 0.255 0.000
H30-H36 Disorders of choroid and retina
0.745 0.255 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.744 0.256 0.000
B37 Candidiasis
0.744 0.256 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.742 0.258 0.000
I35.8 Other aortic valve disorders
0.740 0.259 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.740 0.260 0.000
M60-M63 Disorders of muscles
0.740 0.260 0.000
Y40.8 Other systemic antibiotics
0.739 0.261 0.000
Y00-Y09 Assault
0.739 0.261 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.739 0.261 0.000
H91 Other hearing loss
0.738 0.262 0.000
Z95.0 Presence of cardiac pacemaker
0.738 0.262 0.000
L89 Decubitus ulcer
0.737 0.263 0.000
L40-L45 Papulosquamous disorders
0.737 0.263 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.737 0.263 0.000
O43 Placental disorders
0.736 0.264 0.000
Q80-Q89 Other congenital malformations
0.735 0.265 0.000
J03 Acute tonsillitis
0.735 0.265 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.734 0.266 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.733 0.267 0.000
H52 Disorders of refraction and accommodation
0.733 0.267 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.731 0.269 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.731 0.269 0.000
H61.2 Impacted cerumen
0.730 0.270 0.000
I51.6 Cardiovascular disease, unspecified
0.730 0.270 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.729 0.271 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.729 0.271 0.000
C79 Secondary malignant neoplasm of other sites
0.728 0.272 0.000
V40-V49 Car occupant injured in transport accident
0.727 0.273 0.000
C71 Malignant neoplasm of brain
0.727 0.273 0.000
O85-O92 Complications predominantly related to the puerperium
0.726 0.274 0.000
M22 Disorders of patella
0.726 0.274 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.726 0.274 0.000
J18.1 Lobar pneumonia, unspecified
0.726 0.274 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.725 0.275 0.000
Z95.3 Presence of xenogenic heart valve
0.724 0.276 0.000
Z81 Family history of mental and behavioural disorders
0.723 0.277 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.723 0.277 0.000
S00.8 Superficial injury of other parts of head
0.723 0.277 0.000
I62 Other nontraumatic intracranial haemorrhage
0.723 0.277 0.000
O40 Polyhydramnios
0.722 0.278 0.000
Z29 Need for other prophylactic measures
0.721 0.279 0.000
M65.3 Trigger finger
0.720 0.280 0.000
Y52 Agents primarily affecting the cardiovascular system
0.720 0.280 0.000
X20-X29 Contact with venomous animals and plants
0.719 0.281 0.000
I45 Other conduction disorders
0.719 0.281 0.000
I71.0 Dissection of aorta [any part]
0.719 0.281 0.000
I26 Pulmonary embolism
0.718 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
E89.2 Postprocedural hypoparathyroidism
0.716 0.284 0.000
H91.9 Hearing loss, unspecified
0.715 0.285 0.000
W18 Other fall on same level
0.714 0.286 0.000
E85 Amyloidosis
0.712 0.288 0.000
E84 Cystic fibrosis
0.712 0.288 0.000
E79 Disorders of purine and pyrimidine metabolism
0.712 0.288 0.000
E77 Disorders of glycoprotein metabolism
0.712 0.288 0.000
E76 Disorders of glycosaminoglycan metabolism
0.712 0.288 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.712 0.288 0.000
E74 Other disorders of carbohydrate metabolism
0.712 0.288 0.000
E73 Lactose intolerance
0.712 0.288 0.000
E72 Other disorders of amino-acid metabolism
0.712 0.288 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.712 0.288 0.000
E70 Disorders of aromatic amino-acid metabolism
0.712 0.288 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.712 0.288 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.711 0.289 0.000
Z86.0 Personal history of other neoplasms
0.711 0.289 0.000
Z84 Family history of other conditions
0.711 0.289 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.710 0.289 0.000
I63 Cerebral infarction
0.710 0.290 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.709 0.291 0.000
Z92.9 Personal history of medical treatment, unspecified
0.709 0.291 0.000
Z92.5 Personal history of rehabilitation measures
0.709 0.291 0.000
Z92.0 Personal history of contraception
0.709 0.291 0.000
I20.0 Unstable angina
0.708 0.292 0.000
I33 Acute and subacute endocarditis
0.708 0.292 0.000
B44 Aspergillosis
0.707 0.293 0.000
E00-E07 Disorders of thyroid gland
0.707 0.293 0.000
E29 Testicular dysfunction
0.706 0.294 0.000
C34 Malignant neoplasm of bronchus and lung
0.706 0.294 0.000
E26 Hyperaldosteronism
0.705 0.295 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.704 0.296 0.000
S90-S99 Injuries to the ankle and foot
0.703 0.297 0.000
D55-D59 Haemolytic anaemias
0.703 0.297 0.000
I60 Subarachnoid haemorrhage
0.703 0.297 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.702 0.298 0.000
Y35-Y36 Legal intervention and operations of war
0.702 0.298 0.000
Y10-Y34 Event of undetermined intent
0.702 0.298 0.000
X85-X99 Assault
0.702 0.298 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.702 0.298 0.000
X50-X57 Overexertion, travel and privation
0.702 0.298 0.000
X30-X39 Exposure to forces of nature
0.702 0.298 0.000
X10-X19 Contact with heat and hot substances
0.702 0.298 0.000
X00-X09 Exposure to smoke, fire and flames
0.702 0.298 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.702 0.298 0.000
W75-W84 Other accidental threats to breathing
0.702 0.298 0.000
W65-W74 Accidental drowning and submersion
0.702 0.298 0.000
V98-V99 Other and unspecified transport accidents
0.702 0.298 0.000
V95-V97 Air and space transport accidents
0.702 0.298 0.000
V90-V94 Water transport accidents
0.702 0.298 0.000
V70-V79 Bus occupant injured in transport accident
0.702 0.298 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.702 0.298 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.702 0.298 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.702 0.298 0.000
V01-V09 Pedestrian injured in transport accident
0.702 0.298 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.702 0.298 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.700 0.300 0.000
A04.8 Other specified bacterial intestinal infections
0.700 0.300 0.000
I74 Arterial embolism and thrombosis
0.699 0.301 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.699 0.301 0.000
M34 Systemic sclerosis
0.699 0.301 0.000
M33 Dermatopolymyositis
0.699 0.301 0.000
M32 Systemic lupus erythematosus
0.699 0.301 0.000
M30 Polyarteritis nodosa and related conditions
0.699 0.301 0.000
V80-V89 Other land transport accidents
0.699 0.301 0.000
O32.4 Maternal care for high head at term
0.698 0.302 0.000
J60-J70 Lung diseases due to external agents
0.698 0.302 0.000
F99-F99 Unspecified mental disorder
0.697 0.302 0.000
L81.4 Other melanin hyperpigmentation
0.697 0.303 0.000
I51.4 Myocarditis, unspecified
0.695 0.305 0.000
F80-F89 Disorders of psychological development
0.694 0.306 0.000
B99-B99 Other infectious diseases
0.694 0.306 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.694 0.306 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.694 0.306 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.693 0.307 0.000
M25.3 Other instability of joint
0.692 0.307 0.000
M25.2 Flail joint
0.692 0.307 0.000
M25.1 Fistula of joint
0.692 0.307 0.000
M25.0 Haemarthrosis
0.692 0.307 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.692 0.307 0.000
C51-C58 Malignant neoplasms of female genital organs
0.692 0.308 0.000
I44.3 Other and unspecified atrioventricular block
0.692 0.308 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.691 0.309 0.000
M91-M94 Chondropathies
0.691 0.309 0.000
M25.9 Joint disorder, unspecified
0.691 0.309 0.000
I51.7 Cardiomegaly
0.691 0.309 0.000
W06 Fall involving bed
0.691 0.309 0.000
V10-V19 Pedal cyclist injured in transport accident
0.690 0.309 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.690 0.309 0.000
E87.4 Mixed disorder of acid-base balance
0.690 0.310 0.000
E23.0 Hypopituitarism
0.690 0.310 0.000
M00-M03 Infectious arthropathies
0.689 0.311 0.000
E83.4 Disorders of magnesium metabolism
0.689 0.311 0.000
M25.79 Osteophyte (Site unspecified)
0.688 0.312 0.000
M25.73 Osteophyte (Forearm)
0.688 0.312 0.000
M25.72 Osteophyte (Upper arm)
0.688 0.312 0.000
M25.70 Osteophyte (Multiple sites)
0.688 0.312 0.000
J86 Pyothorax
0.688 0.312 0.000
B95-B98 Bacterial, viral and other infectious agents
0.688 0.312 0.000
M86-M90 Other osteopathies
0.688 0.312 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.688 0.312 0.000
S40 Superficial injury of shoulder and upper arm
0.688 0.312 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.687 0.313 0.000
H50 Other strabismus
0.687 0.313 0.000
S06 Intracranial injury
0.687 0.313 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.687 0.313 0.000
I47 Paroxysmal tachycardia
0.686 0.314 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.686 0.314 0.000
Z80 Family history of malignant neoplasm
0.686 0.314 0.000
I24 Other acute ischaemic heart diseases
0.686 0.314 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.686 0.314 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.686 0.314 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.686 0.314 0.000
E89.5 Postprocedural testicular hypofunction
0.686 0.314 0.000
E89.4 Postprocedural ovarian failure
0.686 0.314 0.000
E89.3 Postprocedural hypopituitarism
0.686 0.314 0.000
E89.1 Postprocedural hypoinsulinaemia
0.686 0.314 0.000
L10-L14 Bullous disorders
0.685 0.315 0.000
D64.8 Other specified anaemias
0.685 0.315 0.000
D64.4 Congenital dyserythropoietic anaemia
0.685 0.315 0.000
D64.3 Other sideroblastic anaemias
0.685 0.315 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.685 0.315 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.685 0.315 0.000
D64.0 Hereditary sideroblastic anaemia
0.685 0.315 0.000
D61 Other aplastic anaemias
0.685 0.315 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.684 0.316 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.684 0.316 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.684 0.316 0.000
E14 Unspecified diabetes mellitus
0.683 0.317 0.000
M40-M43 Deforming dorsopathies
0.682 0.318 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.682 0.318 0.000
I78 Diseases of capillaries
0.682 0.318 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.682 0.318 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.682 0.318 0.000
B65-B83 Helminthiases
0.682 0.318 0.000
B50-B64 Protozoal diseases
0.682 0.318 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.682 0.318 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.682 0.318 0.000
A80-A89 Viral infections of the central nervous system
0.682 0.318 0.000
A75-A79 Rickettsioses
0.682 0.318 0.000
A70-A74 Other diseases caused by chlamydiae
0.682 0.318 0.000
A65-A69 Other spirochaetal diseases
0.682 0.318 0.000
A20-A28 Certain zoonotic bacterial diseases
0.682 0.318 0.000
A15-A19 Tuberculosis
0.682 0.318 0.000
I70 Atherosclerosis
0.682 0.318 0.000
Y59 Other and unspecified vaccines and biological substances
0.680 0.320 0.000
Y58 Bacterial vaccines
0.680 0.320 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.680 0.320 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.680 0.320 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.680 0.320 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.680 0.320 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.680 0.320 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.680 0.320 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.680 0.320 0.000
E87.3 Alkalosis
0.680 0.320 0.000
I44.5 Left posterior fascicular block
0.680 0.320 0.000
I44.4 Left anterior fascicular block
0.680 0.320 0.000
Y43 Primarily systemic agents
0.680 0.320 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.680 0.320 0.000
H40-H42 Glaucoma
0.680 0.320 0.000
A08 Viral and other specified intestinal infections
0.679 0.321 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.679 0.321 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.679 0.321 0.000
H35 Other retinal disorders
0.679 0.321 0.000
I30 Acute pericarditis
0.678 0.321 0.000
M31.3 Wegener's granulomatosis
0.678 0.322 0.000
S50-S59 Injuries to the elbow and forearm
0.678 0.322 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.678 0.322 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.677 0.323 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.677 0.323 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.677 0.323 0.000
E83.8 Other disorders of mineral metabolism
0.677 0.323 0.000
E83.2 Disorders of zinc metabolism
0.677 0.323 0.000
E83.0 Disorders of copper metabolism
0.677 0.323 0.000
M24.07 Loose body in joint (Ankle and foot)
0.676 0.324 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.675 0.325 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.675 0.325 0.000
M66 Spontaneous rupture of synovium and tendon
0.674 0.326 0.000
Z22 Carrier of infectious disease
0.673 0.327 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.673 0.327 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.672 0.328 0.000
M24.1 Other articular cartilage disorders
0.672 0.328 0.000
Y40.0 Penicillins
0.671 0.329 0.000
Z97.3 Presence of spectacles and contact lenses
0.670 0.329 0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)
0.670 0.329 0.000
Z97.1 Presence of artificial limb (complete)(partial)
0.670 0.329 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.670 0.330 0.000
D86 Sarcoidosis
0.670 0.330 0.000
E16 Other disorders of pancreatic internal secretion
0.669 0.331 0.000
M65.34 Trigger finger-Hand
0.669 0.331 0.000
I34 Nonrheumatic mitral valve disorders
0.669 0.331 0.000
O42 Premature rupture of membranes
0.668 0.332 0.000
I49.0 Ventricular fibrillation and flutter
0.668 0.332 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.667 0.333 0.000
D63.0 Anaemia in neoplastic disease
0.667 0.333 0.000
M80-M85 Disorders of bone density and structure
0.666 0.333 0.000
E24 Cushing's syndrome
0.666 0.334 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.666 0.334 0.000
L94 Other localised connective tissue disorders
0.666 0.334 0.000
L93 Lupus erythematosus
0.666 0.334 0.000
L87 Transepidermal elimination disorders
0.666 0.334 0.000
L88 Pyoderma gangrenosum
0.666 0.334 0.000
L86 Keratoderma in diseases classified elsewhere
0.666 0.334 0.000
L83 Acanthosis nigricans
0.666 0.334 0.000
L80 Vitiligo
0.666 0.334 0.000
Q50-Q56 Congenital malformations of genital organs
0.666 0.334 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.665 0.335 0.000
L85.8 Other specified epidermal thickening
0.664 0.336 0.000
E46 Unspecified protein-energy malnutrition
0.664 0.336 0.000
M25.46 Effusion of joint (Lower leg)
0.663 0.337 0.000
S42 Fracture of shoulder and upper arm
0.663 0.337 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.662 0.337 0.000
Q60-Q64 Congenital malformations of the urinary system
0.662 0.338 0.000
Y44.2 Anticoagulants
0.662 0.338 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.662 0.338 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.661 0.339 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.661 0.339 0.000
O32.0 Maternal care for unstable lie
0.661 0.339 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.660 0.339 0.000
O41.0 Oligohydramnios
0.661 0.339 0.000
I51.5 Myocardial degeneration
0.660 0.339 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.660 0.339 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.660 0.339 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.660 0.339 0.000
I51.0 Cardiac septal defect, acquired
0.660 0.339 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.660 0.340 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.659 0.341 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.659 0.341 0.000
L50-L54 Urticaria and erythema
0.659 0.341 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.659 0.341 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.659 0.341 0.000
W29 Contact with other powered hand tools and household machinery
0.658 0.341 0.000
I23 Certain current complications following acute myocardial infarction
0.658 0.342 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.656 0.344 0.000
Y40.9 Systemic antibiotic, unspecified
0.656 0.344 0.000
T66-T78 Other and unspecified effects of external causes
0.655 0.345 0.000
B37.8 Candidiasis of other sites
0.655 0.345 0.000
M24.02 Loose body in joint (Upper arm)
0.655 0.345 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.654 0.346 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.654 0.346 0.000
M21.1 Varus deformity, not elsewhere classified
0.654 0.346 0.000
V20-V29 Motorcycle rider injured in transport accident
0.654 0.346 0.000
O45 Premature separation of placenta [abruptio placentae]
0.652 0.348 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.652 0.348 0.000
O33 Maternal care for known or suspected disproportion
0.652 0.348 0.000
O31 Complications specific to multiple gestation
0.652 0.348 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.651 0.349 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.651 0.349 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.651 0.349 0.000
E34 Other endocrine disorders
0.651 0.349 0.000
E32 Diseases of thymus
0.651 0.349 0.000
E31 Polyglandular dysfunction
0.651 0.349 0.000
E30 Disorders of puberty, not elsewhere classified
0.651 0.349 0.000
E25 Adrenogenital disorders
0.651 0.349 0.000
E20 Hypoparathyroidism
0.651 0.349 0.000
I37.1 Pulmonary valve insufficiency
0.649 0.351 0.000
Z95.2 Presence of prosthetic heart valve
0.649 0.351 0.000
J18.0 Bronchopneumonia, unspecified
0.649 0.351 0.000
J03.9 Acute tonsillitis, unspecified
0.648 0.352 0.000
I72.8 Aneurysm of other specified arteries
0.647 0.353 0.000
H49 Paralytic strabismus
0.647 0.353 0.000
E86 Volume depletion
0.646 0.353 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.646 0.354 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.646 0.354 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.646 0.354 0.000
S10-S19 Injuries to the neck
0.646 0.354 0.000
H52.1 Myopia
0.646 0.354 0.000
W17 Other fall from one level to another
0.645 0.354 0.000
O36 Maternal care for other known or suspected foetal problems
0.645 0.355 0.000
Chapter VI Diseases of the nervous system
0.645 0.355 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.644 0.356 0.000
M25.84 Other specified joint disorders (Hand)
0.644 0.356 0.000
I49.9 Cardiac arrhythmia, unspecified
0.644 0.356 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.643 0.357 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.643 0.357 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.643 0.357 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.643 0.357 0.000
M24.9 Joint derangement, unspecified
0.643 0.357 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.643 0.357 0.000
M24.7 Protrusio acetabuli
0.643 0.357 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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