TreeWAS – Variant ID: rs17609368

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	1.000	0.000
# Top node	1.000	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.999	0.001
Chapter IV Endocrine, nutritional and metabolic diseases	0.997	0.003
E70-E90 Metabolic disorders	0.989	0.011
T81 Complications of procedures, not elsewhere classified	0.985	0.015
T81.8 Other complications of procedures, not elsewhere classified	0.984	0.016
E87 Other disorders of fluid, electrolyte and acid-base balance	0.983	0.017
E65-E68 Obesity and other hyperalimentation	0.974	0.026
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.973	0.027
S50-S59 Injuries to the elbow and forearm	0.969	0.031
Chapter X Diseases of the respiratory system	0.967	0.033
E66 Obesity	0.956	0.044
E87.6 Hypokalaemia	0.953	0.047
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.951	0.049
E66.8 Other obesity	0.949	0.051
Chapter I Certain infectious and parasitic diseases	0.949	0.051
Chapter XXII Codes for special purposes	0.947	0.053
Chapter XII Diseases of the skin and subcutaneous tissue	0.946	0.054
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.943	0.057
S56 Injury of muscle and tendon at forearm level	0.938	0.062
S10-S19 Injuries to the neck	0.933	0.067
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.930	0.070
E86 Volume depletion	0.928	0.072
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.925	0.075
L00-L08 Infections of the skin and subcutaneous tissue	0.916	0.084
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.916	0.084
T84.0 Mechanical complication of internal joint prosthesis	0.912	0.088
J09-J18 Influenza and pneumonia	0.911	0.089
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.911	0.089
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.911	0.089
S70-S79 Injuries to the hip and thigh	0.910	0.090
J40-J47 Chronic lower respiratory diseases	0.901	0.099
J60-J70 Lung diseases due to external agents	0.898	0.102
Chapter XX External causes of morbidity and mortality	0.898	0.102
U80 Agent resistant to penicillin and related antibiotics	0.883	0.117
T83.0 Mechanical complication of urinary (indwelling) catheter	0.882	0.118
E87.7 Fluid overload	0.874	0.126
J15 Bacterial pneumonia, not elsewhere classified	0.874	0.126
J40 Bronchitis, not specified as acute or chronic	0.873	0.127
S80-S89 Injuries to the knee and lower leg	0.871	0.129
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.865	0.135
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.861	0.139
L20-L30 Dermatitis and eczema	0.859	0.141
B95-B98 Bacterial, viral and other infectious agents	0.857	0.143
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.854	0.146
S00-S09 Injuries to the head	0.854	0.146
S72 Fracture of femur	0.852	0.148
L08 Other local infections of skin and subcutaneous tissue	0.849	0.151
L40-L45 Papulosquamous disorders	0.847	0.153
M20-M25 Other joint disorders	0.846	0.154
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.846	0.154
J44 Other chronic obstructive pulmonary disease	0.844	0.156
S90-S99 Injuries to the ankle and foot	0.843	0.157
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.842	0.158
M05-M14 Inflammatory polyarthropathies	0.839	0.161
S40-S49 Injuries to the shoulder and upper arm	0.837	0.163
Chapter V Mental and behavioural disorders	0.830	0.170
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.823	0.177
U80.8 Agent resistant to other penicillin-related antibiotic	0.817	0.183
E66.0 Obesity due to excess calories	0.816	0.184
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.815	0.185
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.812	0.188
J15.1 Pneumonia due to Pseudomonas	0.811	0.189
W20-W49 Exposure to inanimate mechanical forces	0.810	0.190
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.809	0.191
T93 Sequelae of injuries of lower limb	0.809	0.191
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.806	0.194
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.805	0.195
S72.0 Fracture of neck of femur	0.805	0.195
S14 Injury of nerves and spinal cord at neck level	0.801	0.199
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.800	0.200
L40 Psoriasis	0.800	0.200
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.798	0.202
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.798	0.202
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.797	0.203
S06 Intracranial injury	0.794	0.206
J69 Pneumonitis due to solids and liquids	0.794	0.206
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.791	0.209
S51 Open wound of forearm	0.791	0.209
T90 Sequelae of injuries of head	0.791	0.209
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.789	0.211
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.788	0.212
S12 Fracture of neck	0.788	0.212
U80.1 Methicillin resistant agent	0.787	0.213
E87.5 Hyperkalaemia	0.782	0.218
M86-M90 Other osteopathies	0.781	0.219
L40.5 Arthropathic psoriasis	0.779	0.221
T81.4 Infection following a procedure, not elsewhere classified	0.778	0.222
M07 Psoriatic and enteropathic arthropathies	0.778	0.222
T91 Sequelae of injuries of neck and trunk	0.777	0.223
T83.1 Mechanical complication of other urinary devices and implants	0.776	0.224
E50-E64 Other nutritional deficiencies	0.774	0.226
F40-F48 Neurotic, stress-related and somatoform disorders	0.773	0.227
L29 Pruritus	0.773	0.227
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.772	0.228
E20-E35 Disorders of other endocrine glands	0.772	0.228
E87.0 Hyperosmolality and hypernatraemia	0.772	0.228
S72.00 Fracture of neck of femur (closed)	0.771	0.229
S86 Injury of muscle and tendon at lower leg level	0.770	0.230
D80-D89 Certain disorders involving the immune mechanism	0.770	0.230
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.770	0.230
L03 Cellulitis	0.769	0.231
T83.3 Mechanical complication of intra-uterine contraceptive device	0.767	0.233
T20-T25 Burns and corrosions of external body surface, specified by site	0.767	0.233
S50 Superficial injury of forearm	0.766	0.234
B65-B83 Helminthiases	0.765	0.235
T84.3 Mechanical complication of other bone devices, implants and grafts	0.762	0.238
E87.2 Acidosis	0.760	0.240
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.759	0.241
S19 Other and unspecified injuries of neck	0.759	0.241
V20-V29 Motorcycle rider injured in transport accident	0.758	0.242
E73 Lactose intolerance	0.756	0.244
T66-T78 Other and unspecified effects of external causes	0.756	0.244
J15.4 Pneumonia due to other streptococci	0.750	0.250
J17 Pneumonia in diseases classified elsewhere	0.750	0.250
T88 Other complications of surgical and medical care, not elsewhere classified	0.749	0.251
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.746	0.254
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.744	0.256
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.743	0.257
A00-A09 Intestinal infectious diseases	0.741	0.259
M96.0 Pseudarthrosis after fusion or arthrodesis	0.736	0.264
S79 Other and unspecified injuries of hip and thigh	0.735	0.265
B00 Herpesviral [herpes simplex] infections	0.734	0.266
M07.3 Other psoriatic arthropathies	0.734	0.266
M60-M63 Disorders of muscles	0.734	0.266
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.734	0.266
E88 Other metabolic disorders	0.733	0.266
M91-M94 Chondropathies	0.733	0.267
M25 Other joint disorders, not elsewhere classified	0.732	0.268
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.732	0.268
W50-W64 Exposure to animate mechanical forces	0.732	0.268
L01 Impetigo	0.730	0.270
X60-X84 Intentional self-harm	0.729	0.271
M23 Internal derangement of knee	0.729	0.271
T80 Complications following infusion, transfusion and therapeutic injection	0.727	0.272
T81.7 Vascular complications following a procedure, not elsewhere classified	0.724	0.276
Q60-Q64 Congenital malformations of the urinary system	0.721	0.279
J95-J99 Other diseases of the respiratory system	0.720	0.280
J69.0 Pneumonitis due to food and vomit	0.720	0.280
A15-A19 Tuberculosis	0.718	0.282
X40-X49 Accidental poisoning by and exposure to noxious substances	0.718	0.282
L28 Lichen simplex chronicus and prurigo	0.717	0.282
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
D86 Sarcoidosis	0.716	0.284
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.716	0.284
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.714	0.286
B02 Zoster [herpes zoster]	0.713	0.287
L02 Cutaneous abscess, furuncle and carbuncle	0.712	0.288
J67 Hypersensitivity pneumonitis due to organic dust	0.712	0.288
E65 Localised adiposity	0.710	0.290
M30 Polyarteritis nodosa and related conditions	0.709	0.291
E85 Amyloidosis	0.709	0.291
E84 Cystic fibrosis	0.709	0.291
E79 Disorders of purine and pyrimidine metabolism	0.709	0.291
E77 Disorders of glycoprotein metabolism	0.709	0.291
E76 Disorders of glycosaminoglycan metabolism	0.709	0.291
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.709	0.291
E74 Other disorders of carbohydrate metabolism	0.709	0.291
E72 Other disorders of amino-acid metabolism	0.709	0.291
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.709	0.291
E70 Disorders of aromatic amino-acid metabolism	0.709	0.291
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.709	0.291
S90 Superficial injury of ankle and foot	0.708	0.292
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.706	0.294
S14.1 Other and unspecified injuries of cervical spinal cord	0.706	0.294
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.705	0.295
M23.3 Other meniscus derangements	0.705	0.295
E87.4 Mixed disorder of acid-base balance	0.705	0.295
E40-E46 Malnutrition	0.704	0.295
M80-M85 Disorders of bone density and structure	0.704	0.296
J13 Pneumonia due to Streptococcus pneumoniae	0.704	0.296
T90.5 Sequelae of intracranial injury	0.703	0.297
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.702	0.298
F99-F99 Unspecified mental disorder	0.701	0.299
S42 Fracture of shoulder and upper arm	0.700	0.300
B15-B19 Viral hepatitis	0.699	0.301
S06.6 Traumatic subarachnoid haemorrhage	0.698	0.302
Q00-Q07 Congenital malformations of the nervous system	0.698	0.302
E67 Other hyperalimentation	0.698	0.302
E68 Sequelae of hyperalimentation	0.698	0.302
T92 Sequelae of injuries of upper limb	0.698	0.302
T83.2 Mechanical complication of graft of urinary organ	0.697	0.303
T94 Sequelae of injuries involving multiple and unspecified body regions	0.697	0.303
U81 Agent resistant to vancomycin and related antibiotics	0.695	0.305
M31 Other necrotising vasculopathies	0.695	0.305
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.695	0.305
S59 Other and unspecified injuries of forearm	0.695	0.305
S58 Traumatic amputation of forearm	0.695	0.305
S57 Crushing injury of forearm	0.695	0.305
S55 Injury of blood vessels at forearm level	0.695	0.305
S54 Injury of nerves at forearm level	0.695	0.305
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.695	0.305
M96.8 Other postprocedural musculoskeletal disorders	0.694	0.306
S86.8 Injury of other muscles and tendons at lower leg level	0.694	0.306
M06 Other rheumatoid arthritis	0.692	0.308
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.692	0.308
Q20-Q28 Congenital malformations of the circulatory system	0.691	0.309
X58-X59 Accidental exposure to other and unspecified factors	0.691	0.309
E87.3 Alkalosis	0.691	0.309
T87 Complications peculiar to reattachment and amputation	0.690	0.310
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.689	0.311
U80.0 Penicillin resistant agent	0.689	0.311
T79-T79 Certain early complications of trauma	0.689	0.311
Q12 Congenital lens malformations	0.688	0.312
F60-F69 Disorders of adult personality and behaviour	0.688	0.312
B20-B24 Human immunodeficiency virus [HIV] disease	0.687	0.313
L03.3 Cellulitis of trunk	0.687	0.313
Y60-Y69 Misadventures to patients during surgical and medical care	0.686	0.314
T15-T19 Effects of foreign body entering through natural orifice	0.686	0.314
Q38-Q45 Other congenital malformations of the digestive system	0.685	0.315
E66.2 Extreme obesity with alveolar hypoventilation	0.685	0.315
E66.1 Drug-induced obesity	0.685	0.315
S09 Other and unspecified injuries of head	0.685	0.315
W22 Striking against or struck by other objects	0.685	0.315
Q18 Other congenital malformations of face and neck	0.683	0.317
M35 Other systemic involvement of connective tissue	0.683	0.317
L29.0 Pruritus ani	0.683	0.317
W25 Contact with sharp glass	0.682	0.318
M45-M49 Spondylopathies	0.681	0.319
B85-B89 Pediculosis, acariasis and other infestations	0.680	0.320
B50-B64 Protozoal diseases	0.680	0.320
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.680	0.320
A75-A79 Rickettsioses	0.680	0.320
A70-A74 Other diseases caused by chlamydiae	0.680	0.320
A65-A69 Other spirochaetal diseases	0.680	0.320
A20-A28 Certain zoonotic bacterial diseases	0.680	0.320
S41 Open wound of shoulder and upper arm	0.679	0.321
L10-L14 Bullous disorders	0.678	0.322
Chapter VIII Diseases of the ear and mastoid process	0.677	0.322
J86 Pyothorax	0.677	0.323
S02 Fracture of skull and facial bones	0.677	0.323
F43 Reaction to severe stress, and adjustment disorders	0.677	0.323
T95 Sequelae of burns, corrosions and frostbite	0.676	0.324
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.676	0.324
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.676	0.324
M40-M43 Deforming dorsopathies	0.675	0.325
M07.39 Other psoriatic arthropathies (Site unspecified)	0.675	0.325
S20-S29 Injuries to the thorax	0.675	0.325
X20-X29 Contact with venomous animals and plants	0.674	0.325
E00-E07 Disorders of thyroid gland	0.674	0.326
W20 Struck by thrown, projected or falling object	0.674	0.326
T98 Sequelae of other and unspecified effects of external causes	0.673	0.327
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.673	0.327
S56.2 Injury of other flexor muscle and tendon at forearm level	0.673	0.327
S56.7 Injury of multiple muscles and tendons at forearm level	0.673	0.327
S56.5 Injury of other extensor muscle and tendon at forearm level	0.673	0.327
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.673	0.327
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.673	0.327
E27 Other disorders of adrenal gland	0.672	0.328
M14 Arthropathies in other diseases classified elsewhere	0.672	0.328
M24 Other specific joint derangements	0.671	0.329
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.670	0.330
A30-A49 Other bacterial diseases	0.669	0.331
S17 Crushing injury of neck	0.669	0.331
S15 Injury of blood vessels at neck level	0.669	0.331
S11 Open wound of neck	0.669	0.331
S10 Superficial injury of neck	0.669	0.331
S18 Traumatic amputation at neck level	0.669	0.331
S16 Injury of muscle and tendon at neck level	0.669	0.331
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.668	0.332
S72.4 Fracture of lower end of femur	0.668	0.332
S83.2 Tear of meniscus, current	0.667	0.333
L20 Atopic dermatitis	0.666	0.334
J10 Influenza due to identified influenza virus	0.666	0.334
B25-B34 Other viral diseases	0.665	0.335
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.665	0.335
F44 Dissociative [conversion] disorders	0.664	0.336
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.661	0.339
L05 Pilonidal cyst	0.659	0.341
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.658	0.342
M85 Other disorders of bone density and structure	0.658	0.342
M00-M03 Infectious arthropathies	0.658	0.342
T90.9 Sequelae of unspecified injury of head	0.658	0.342
S81 Open wound of lower leg	0.657	0.342
L04 Acute lymphadenitis	0.657	0.343
L00 Staphylococcal scalded skin syndrome	0.657	0.343
A80-A89 Viral infections of the central nervous system	0.657	0.343
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.657	0.343
Q35-Q37 Cleft lip and cleft palate	0.657	0.343
Q30-Q34 Congenital malformations of the respiratory system	0.657	0.343
L29.9 Pruritus, unspecified	0.656	0.344
Q50-Q56 Congenital malformations of genital organs	0.655	0.345
D86.1 Sarcoidosis of lymph nodes	0.655	0.345
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.653	0.347
J12 Viral pneumonia, not elsewhere classified	0.653	0.347
J09 Influenza due to certain identified influenza virus	0.653	0.347
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.653	0.347
U50 Level of care administered to neonates	0.653	0.347
U07 Emergency use of U07	0.653	0.347
U06 Emergency use of U06	0.653	0.347
U04 Severe acute respiratory syndrome [SARS]	0.653	0.347
U52 First in a series of a regular day/night admissions	0.653	0.347
S78 Traumatic amputation of hip and thigh	0.652	0.348
S77 Crushing injury of hip and thigh	0.652	0.348
S76 Injury of muscle and tendon at hip and thigh level	0.652	0.348
S75 Injury of blood vessels at hip and thigh level	0.652	0.348
S74 Injury of nerves at hip and thigh level	0.652	0.348
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.652	0.348
X50-X57 Overexertion, travel and privation	0.651	0.348
S12.2 Fracture of other specified cervical vertebra	0.649	0.351
B99-B99 Other infectious diseases	0.649	0.351
S06.4 Epidural haemorrhage	0.647	0.353
F80-F89 Disorders of psychological development	0.647	0.353
V80-V89 Other land transport accidents	0.647	0.353
S51.7 Multiple open wounds of forearm	0.646	0.354
M25.5 Pain in joint	0.646	0.354
F40 Phobic anxiety disorders	0.646	0.354
J41 Simple and mucopurulent chronic bronchitis	0.646	0.354
M33 Dermatopolymyositis	0.645	0.355
J70 Respiratory conditions due to other external agents	0.644	0.356
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.644	0.356
J66 Airway disease due to specific organic dust	0.644	0.356
J63 Pneumoconiosis due to other inorganic dusts	0.644	0.356
J62 Pneumoconiosis due to dust containing silica	0.644	0.356
J65 Pneumoconiosis associated with tuberculosis	0.644	0.356
J64 Unspecified pneumoconiosis	0.644	0.356
J60 Coalworker's pneumoconiosis	0.644	0.356
Y35-Y36 Legal intervention and operations of war	0.644	0.356
Y10-Y34 Event of undetermined intent	0.644	0.356
X85-X99 Assault	0.644	0.356
X30-X39 Exposure to forces of nature	0.644	0.356
X10-X19 Contact with heat and hot substances	0.644	0.356
X00-X09 Exposure to smoke, fire and flames	0.644	0.356
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.644	0.356
W75-W84 Other accidental threats to breathing	0.644	0.356
W65-W74 Accidental drowning and submersion	0.644	0.356
V98-V99 Other and unspecified transport accidents	0.644	0.356
V95-V97 Air and space transport accidents	0.644	0.356
V90-V94 Water transport accidents	0.644	0.356
V70-V79 Bus occupant injured in transport accident	0.644	0.356
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.644	0.356
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.644	0.356
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.644	0.356
V01-V09 Pedestrian injured in transport accident	0.644	0.356
T93.0 Sequelae of open wound of lower limb	0.643	0.357
J80-J84 Other respiratory diseases principally affecting the interstitium	0.643	0.357
J11 Influenza, virus not identified	0.641	0.359
S06.5 Traumatic subdural haemorrhage	0.641	0.359
E87.1 Hypo-osmolality and hyponatraemia	0.640	0.360
L40.0 Psoriasis vulgaris	0.637	0.363
S12.7 Multiple fractures of cervical spine	0.637	0.363
M35.0 Sicca syndrome [Sjogren]	0.637	0.363
M89 Other disorders of bone	0.636	0.364
Y00-Y09 Assault	0.635	0.365
E34 Other endocrine disorders	0.635	0.365
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.634	0.365
S19.8 Other specified injuries of neck	0.634	0.366
S89 Other and unspecified injuries of lower leg	0.634	0.366
B80 Enterobiasis	0.633	0.367
M23.30 Other meniscus derangements (Multiple sites)	0.633	0.367
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.632	0.368
S99 Other and unspecified injuries of ankle and foot	0.631	0.369
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.631	0.369
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.630	0.370
E80 Disorders of porphyrin and bilirubin metabolism	0.630	0.370
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.630	0.370
J90-J94 Other diseases of pleura	0.629	0.371
M85.8 Other specified disorders of bone density and structure	0.629	0.371
T88.5 Other complications of anaesthesia	0.628	0.372
B90-B94 Sequelae of infectious and parasitic diseases	0.628	0.372
L03.1 Cellulitis of other parts of limb	0.627	0.373
J15.9 Bacterial pneumonia, unspecified	0.626	0.374
J15.8 Other bacterial pneumonia	0.626	0.374
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.626	0.374
J15.5 Pneumonia due to Escherichia coli	0.626	0.374
J15.3 Pneumonia due to streptococcus, group B	0.626	0.374
J15.0 Pneumonia due to Klebsiella pneumoniae	0.626	0.374
L08.8 Other specified local infections of skin and subcutaneous tissue	0.626	0.374
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.625	0.374
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.625	0.375
M25.3 Other instability of joint	0.625	0.375
S49 Other and unspecified injuries of shoulder and upper arm	0.625	0.375
S88 Traumatic amputation of lower leg	0.625	0.375
S87 Crushing injury of lower leg	0.625	0.375
S85 Injury of blood vessels at lower leg level	0.625	0.375
S84 Injury of nerves at lower leg level	0.625	0.375
T81.9 Unspecified complication of procedure	0.623	0.377
B35-B49 Mycoses	0.623	0.377
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.622	0.378
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.621	0.379
T88.7 Unspecified adverse effect of drug or medicament	0.620	0.380
J43 Emphysema	0.619	0.381
U51 Admission status on psychiatric patients	0.619	0.381
T63 Toxic effect of contact with venomous animals	0.618	0.382
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.618	0.382
E61 Deficiency of other nutrient elements	0.617	0.383
T91.9 Sequelae of unspecified injury of neck and trunk	0.616	0.384
L28.0 Lichen simplex chronicus	0.616	0.384
L25 Unspecified contact dermatitis	0.616	0.384
L24 Irritant contact dermatitis	0.616	0.384
L23 Allergic contact dermatitis	0.616	0.384
L21 Seborrhoeic dermatitis	0.616	0.384
L26 Exfoliative dermatitis	0.616	0.384
L22 Diaper [napkin] dermatitis	0.616	0.384
S80 Superficial injury of lower leg	0.616	0.384
S91 Open wound of ankle and foot	0.615	0.385
M34 Systemic sclerosis	0.615	0.385
D70-D77 Other diseases of blood and blood-forming organs	0.614	0.386
J15.2 Pneumonia due to staphylococcus	0.614	0.386
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.614	0.386
M99 Biomechanical lesions, not elsewhere classified	0.613	0.387
W55 Bitten or struck by other mammals	0.612	0.387
B00.1 Herpesviral vesicular dermatitis	0.612	0.388
S08 Traumatic amputation of part of head	0.612	0.388
S07 Crushing injury of head	0.612	0.388
S04 Injury of cranial nerves	0.612	0.388
S03 Dislocation, sprain and strain of joints and ligaments of head	0.612	0.388
V40-V49 Car occupant injured in transport accident	0.612	0.388
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.611	0.389
A07 Other protozoal intestinal diseases	0.611	0.389
S72.9 Fracture of femur, part unspecified	0.611	0.389
S72.8 Fractures of other parts of femur	0.611	0.389
S72.7 Multiple fractures of femur	0.611	0.389
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.611	0.389
S42.0 Fracture of clavicle	0.611	0.389
L40.8 Other psoriasis	0.610	0.389
S79.9 Unspecified injury of hip and thigh	0.610	0.390
A50-A64 Infections with a predominantly sexual mode of transmission	0.609	0.390
D86.9 Sarcoidosis, unspecified	0.610	0.390
M90 Osteopathies in diseases classified elsewhere	0.609	0.390
J44.8 Other specified chronic obstructive pulmonary disease	0.609	0.391
S71 Open wound of hip and thigh	0.609	0.391
S72.2 Subtrochanteric fracture	0.609	0.391
M23.8 Other internal derangements of knee	0.609	0.391
F99 Mental disorder, not otherwise specified	0.609	0.391
L08.1 Erythrasma	0.608	0.391
L08.0 Pyoderma	0.608	0.391
M45 Ankylosing spondylitis	0.608	0.392
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.608	0.392
L44 Other papulosquamous disorders	0.607	0.393
L41 Parapsoriasis	0.607	0.393
L45 Papulosquamous disorders in diseases classified elsewhere	0.607	0.393
L42 Pityriasis rosea	0.607	0.393
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.607	0.393
M32 Systemic lupus erythematosus	0.607	0.393
S98 Traumatic amputation of ankle and foot	0.605	0.395
S97 Crushing injury of ankle and foot	0.605	0.395
S96 Injury of muscle and tendon at ankle and foot level	0.605	0.395
S95 Injury of blood vessels at ankle and foot level	0.605	0.395
S94 Injury of nerves at ankle and foot level	0.605	0.395
M86 Osteomyelitis	0.604	0.396
B06 Rubella [German measles]	0.604	0.396
B05 Measles	0.604	0.396
B01 Varicella [chickenpox]	0.604	0.396
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.604	0.396
B04 Monkeypox	0.604	0.396
B03 Smallpox	0.604	0.396
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.603	0.396
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.603	0.397
M25.7 Osteophyte	0.603	0.397
M12 Other specific arthropathies	0.602	0.398
M09 Juvenile arthritis in diseases classified elsewhere	0.602	0.398
M08 Juvenile arthritis	0.602	0.398
M25.55 Pain in joint (Pelvic region and thigh)	0.602	0.398
S92 Fracture of foot, except ankle	0.601	0.399
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.601	0.399
S48 Traumatic amputation of shoulder and upper arm	0.600	0.399
S45 Injury of blood vessels at shoulder and upper arm level	0.600	0.399
S44 Injury of nerves at shoulder and upper arm level	0.600	0.399
S47 Crushing injury of shoulder and upper arm	0.600	0.399
Q63 Other congenital malformations of kidney	0.600	0.400
S06.9 Intracranial injury, unspecified	0.600	0.400
T58 Toxic effect of carbon monoxide	0.599	0.400
S72.1 Pertrochanteric fracture	0.599	0.401
S51.0 Open wound of elbow	0.599	0.401
S06.3 Focal brain injury	0.598	0.402
Q12.0 Congenital cataract	0.598	0.402
S50.8 Other superficial injuries of forearm	0.597	0.403
L01.0 Impetigo [any organism] [any site]	0.596	0.404
S72.3 Fracture of shaft of femur	0.596	0.404
W44 Foreign body entering into or through eye or natural orifice	0.596	0.404
T84.1 Mechanical complication of internal fixation device of bones of limb	0.596	0.404
W22.9 Unspecified place	0.595	0.405
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.595	0.405
F70-F79 Mental retardation	0.595	0.405
T93.9 Sequelae of unspecified injury of lower limb	0.594	0.406
Q80-Q89 Other congenital malformations	0.593	0.407
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.593	0.407
S90.9 Superficial injury of ankle and foot, unspecified	0.593	0.407
E29 Testicular dysfunction	0.593	0.407
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.593	0.407
F48 Other neurotic disorders	0.592	0.408
B00.4 Herpesviral encephalitis	0.592	0.408
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.592	0.408
T91.8 Sequelae of other specified injuries of neck and trunk	0.592	0.408
T78 Adverse effects, not elsewhere classified	0.591	0.409
W25.9 Unspecified place	0.591	0.409
J86.9 Pyothorax without fistula	0.591	0.409
M60 Myositis	0.591	0.409
M13 Other arthritis	0.590	0.410
E73.9 Lactose intolerance, unspecified	0.589	0.411
Q18.0 Sinus, fistula and cyst of branchial cleft	0.589	0.411
F42 Obsessive-compulsive disorder	0.587	0.412
B02.9 Zoster without complication	0.587	0.413
S41.0 Open wound of shoulder	0.587	0.413

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations