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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17639656
log Bayes Factor = 16.0288
Chromosome 10   position 119,493,705  (GRCh37) Explore rs17639656 on Ensembl!
Variant rs17639656 is part of Cluster X0069

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.996 0.004 0.000
I21 Acute myocardial infarction
0.994 0.006 0.000
I21.9 Acute myocardial infarction, unspecified
0.992 0.008 0.000
D50-D53 Nutritional anaemias
0.991 0.009 0.000
M15-M19 Arthrosis
0.990 0.010 0.000
M20-M25 Other joint disorders
0.990 0.010 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.990 0.010 0.000
D50 Iron deficiency anaemia
0.990 0.010 0.000
M45-M49 Spondylopathies
0.988 0.012 0.000
I25 Chronic ischaemic heart disease
0.987 0.013 0.000
K90-K93 Other diseases of the digestive system
0.987 0.013 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.985 0.015 0.000
Chapter XX External causes of morbidity and mortality
0.982 0.018 0.000
K92 Other diseases of digestive system
0.979 0.021 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.977 0.023 0.000
M47 Spondylosis
0.975 0.025 0.000
D50.8 Other iron deficiency anaemias
0.972 0.028 0.000
D50.9 Iron deficiency anaemia, unspecified
0.972 0.028 0.000
I30-I52 Other forms of heart disease
0.969 0.031 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.969 0.031 0.000
I25.2 Old myocardial infarction
0.967 0.033 0.000
M25 Other joint disorders, not elsewhere classified
0.961 0.039 0.000
Chapter VIII Diseases of the ear and mastoid process
0.957 0.043 0.000
M47.8 Other spondylosis
0.956 0.044 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.952 0.048 0.000
K55-K64 Other diseases of intestines
0.951 0.049 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.948 0.052 0.000
I20 Angina pectoris
0.947 0.053 0.000
I73 Other peripheral vascular diseases
0.947 0.053 0.000
S80-S89 Injuries to the knee and lower leg
0.947 0.053 0.000
K92.1 Melaena
0.933 0.067 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.931 0.069 0.000
M05-M14 Inflammatory polyarthropathies
0.930 0.070 0.000
K70-K77 Diseases of liver
0.928 0.072 0.000
M16 Coxarthrosis [arthrosis of hip]
0.926 0.074 0.000
M31 Other necrotising vasculopathies
0.923 0.077 0.000
Chapter V Mental and behavioural disorders
0.919 0.081 0.000
I73.9 Peripheral vascular disease, unspecified
0.919 0.081 0.000
W00-W19 Falls
0.916 0.084 0.000
S80 Superficial injury of lower leg
0.912 0.088 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.911 0.089 0.000
M18 Arthrosis of first carpometacarpal joint
0.908 0.092 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.907 0.093 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.906 0.094 0.000
M50-M54 Other dorsopathies
0.906 0.094 0.000
M25.7 Osteophyte
0.903 0.097 0.000
K59 Other functional intestinal disorders
0.903 0.097 0.000
M17 Gonarthrosis [arthrosis of knee]
0.900 0.100 0.000
M86-M90 Other osteopathies
0.900 0.100 0.000
I51 Complications and ill-defined descriptions of heart disease
0.899 0.101 0.000
K08 Other disorders of teeth and supporting structures
0.892 0.108 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.889 0.111 0.000
M80-M85 Disorders of bone density and structure
0.887 0.113 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.882 0.118 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.879 0.121 0.000
I72 Other aneurysm
0.878 0.122 0.000
S90-S99 Injuries to the ankle and foot
0.874 0.126 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.873 0.127 0.000
I20.9 Angina pectoris, unspecified
0.871 0.129 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.870 0.130 0.000
H90-H95 Other disorders of ear
0.865 0.135 0.000
M17.0 Primary gonarthrosis, bilateral
0.864 0.136 0.000
I44 Atrioventricular and left bundle-branch block
0.863 0.137 0.000
S80.9 Superficial injury of lower leg, unspecified
0.862 0.138 0.000
I20.0 Unstable angina
0.851 0.149 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.848 0.152 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.847 0.153 0.000
K63 Other diseases of intestine
0.846 0.154 0.000
M31.6 Other giant cell arteritis
0.843 0.157 0.000
M47.82 Other spondylosis (Cervical region)
0.841 0.159 0.000
M11 Other crystal arthropathies
0.841 0.159 0.000
K35-K38 Diseases of appendix
0.840 0.160 0.000
I51.8 Other ill-defined heart diseases
0.838 0.162 0.000
I22 Subsequent myocardial infarction
0.837 0.163 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.836 0.164 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.834 0.165 0.000
I50 Heart failure
0.832 0.168 0.000
M46 Other inflammatory spondylopathies
0.831 0.169 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.831 0.169 0.000
D60-D64 Aplastic and other anaemias
0.830 0.170 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.829 0.171 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.827 0.173 0.000
H80-H83 Diseases of inner ear
0.826 0.174 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.824 0.176 0.000
F30-F39 Mood [affective] disorders
0.822 0.178 0.000
S10-S19 Injuries to the neck
0.821 0.179 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.820 0.180 0.000
M50 Cervical disk disorders
0.817 0.183 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.815 0.185 0.000
M13 Other arthritis
0.814 0.186 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.814 0.186 0.000
T82.3 Mechanical complication of other vascular grafts
0.814 0.186 0.000
Chapter XXI Factors influencing health status and contact with health services
0.813 0.187 0.000
K75 Other inflammatory liver diseases
0.812 0.188 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.809 0.191 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.808 0.192 0.000
M47.1 Other spondylosis with myelopathy
0.808 0.192 0.000
I49 Other cardiac arrhythmias
0.807 0.193 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.805 0.195 0.000
X60-X84 Intentional self-harm
0.805 0.195 0.000
Y83.6 Removal of other organ (partial) (total)
0.802 0.198 0.000
Z86 Personal history of certain other diseases
0.800 0.200 0.000
I20.1 Angina pectoris with documented spasm
0.800 0.200 0.000
K92.0 Haematemesis
0.799 0.201 0.000
T42.4 Benzodiazepines
0.798 0.202 0.000
K76 Other diseases of liver
0.796 0.204 0.000
K02 Dental caries
0.793 0.207 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.793 0.207 0.000
K92.8 Other specified diseases of digestive system
0.792 0.208 0.000
M47.86 Other spondylosis (Lumbar region)
0.792 0.208 0.000
Q50-Q56 Congenital malformations of genital organs
0.792 0.208 0.000
M16.9 Coxarthrosis, unspecified
0.791 0.209 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.790 0.210 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.790 0.210 0.000
K59.0 Constipation
0.789 0.211 0.000
W19 Unspecified fall
0.787 0.212 0.000
M25.3 Other instability of joint
0.787 0.212 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.787 0.213 0.000
K55 Vascular disorders of intestine
0.787 0.213 0.000
M47.9 Spondylosis, unspecified
0.786 0.214 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.786 0.214 0.000
I78 Diseases of capillaries
0.784 0.216 0.000
Chapter VI Diseases of the nervous system
0.783 0.217 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.782 0.218 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.781 0.219 0.000
M23 Internal derangement of knee
0.781 0.219 0.000
M87 Osteonecrosis
0.780 0.220 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.779 0.221 0.000
I30 Acute pericarditis
0.779 0.221 0.000
I05-I09 Chronic rheumatic heart diseases
0.778 0.222 0.000
M49 Spondylopathies in diseases classified elsewhere
0.778 0.222 0.000
M11.2 Other chondrocalcinosis
0.777 0.223 0.000
K26 Duodenal ulcer
0.777 0.223 0.000
H65-H75 Diseases of middle ear and mastoid
0.776 0.224 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.775 0.225 0.000
M54 Dorsalgia
0.774 0.225 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.774 0.226 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.773 0.227 0.000
I74 Arterial embolism and thrombosis
0.771 0.229 0.000
Chapter VII Diseases of the eye and adnexa
0.770 0.230 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.770 0.230 0.000
M16.1 Other primary coxarthrosis
0.770 0.230 0.000
Chapter XXII Codes for special purposes
0.769 0.231 0.000
K59.3 Megacolon, not elsewhere classified
0.769 0.231 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.769 0.231 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.768 0.231 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.768 0.232 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.767 0.233 0.000
W07 Fall involving chair
0.767 0.233 0.000
Z86.0 Personal history of other neoplasms
0.766 0.234 0.000
R79 Other abnormal findings of blood chemistry
0.766 0.234 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.765 0.235 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.764 0.236 0.000
M34 Systemic sclerosis
0.763 0.237 0.000
K37 Unspecified appendicitis
0.763 0.237 0.000
M65-M68 Disorders of synovium and tendon
0.762 0.238 0.000
I72.4 Aneurysm of artery of lower extremity
0.761 0.239 0.000
F33 Recurrent depressive disorder
0.761 0.239 0.000
S70-S79 Injuries to the hip and thigh
0.760 0.240 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.760 0.240 0.000
I44.7 Left bundle-branch block, unspecified
0.758 0.241 0.000
S80.8 Other superficial injuries of lower leg
0.758 0.242 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.755 0.245 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.755 0.245 0.000
M05 Seropositive rheumatoid arthritis
0.755 0.245 0.000
I27 Other pulmonary heart diseases
0.755 0.245 0.000
Z86.4 Personal history of psychoactive substance abuse
0.754 0.246 0.000
M25.76 Osteophyte (Lower leg)
0.753 0.246 0.000
M84 Disorders of continuity of bone
0.753 0.247 0.000
H91 Other hearing loss
0.753 0.247 0.000
I50.0 Congestive heart failure
0.752 0.248 0.000
M25.78 Osteophyte (Other)
0.751 0.249 0.000
R25 Abnormal involuntary movements
0.750 0.250 0.000
M60-M63 Disorders of muscles
0.750 0.250 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.749 0.251 0.000
W06 Fall involving bed
0.748 0.252 0.000
V80-V89 Other land transport accidents
0.746 0.253 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.745 0.255 0.000
T93 Sequelae of injuries of lower limb
0.744 0.256 0.000
R21 Rash and other nonspecific skin eruption
0.743 0.257 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.742 0.258 0.000
D52 Folate deficiency anaemia
0.742 0.258 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.742 0.258 0.000
X50-X57 Overexertion, travel and privation
0.742 0.258 0.000
M25.9 Joint disorder, unspecified
0.740 0.260 0.000
D80-D89 Certain disorders involving the immune mechanism
0.740 0.260 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.740 0.260 0.000
H81 Disorders of vestibular function
0.740 0.260 0.000
M13.9 Arthritis, unspecified
0.739 0.261 0.000
W19.9 Unspecified place
0.739 0.261 0.000
M25.71 Osteophyte (Shoulder region)
0.738 0.262 0.000
M16.7 Other secondary coxarthrosis
0.738 0.262 0.000
K55.2 Angiodysplasia of colon
0.737 0.263 0.000
M24 Other specific joint derangements
0.737 0.263 0.000
I49.9 Cardiac arrhythmia, unspecified
0.736 0.264 0.000
M20 Acquired deformities of fingers and toes
0.734 0.266 0.000
Z95.0 Presence of cardiac pacemaker
0.734 0.266 0.000
M21 Other acquired deformities of limbs
0.733 0.267 0.000
I77 Other disorders of arteries and arterioles
0.732 0.267 0.000
I35 Nonrheumatic aortic valve disorders
0.732 0.268 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.732 0.268 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.732 0.268 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.732 0.268 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.731 0.269 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.731 0.269 0.000
K72 Hepatic failure, not elsewhere classified
0.731 0.269 0.000
S83.2 Tear of meniscus, current
0.730 0.270 0.000
Q60-Q64 Congenital malformations of the urinary system
0.730 0.270 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.729 0.271 0.000
I31 Other diseases of pericardium
0.728 0.272 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.728 0.272 0.000
T79-T79 Certain early complications of trauma
0.728 0.272 0.000
K61 Abscess of anal and rectal regions
0.727 0.273 0.000
K63.1 Perforation of intestine (nontraumatic)
0.727 0.273 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.727 0.273 0.000
M80 Osteoporosis with pathological fracture
0.726 0.273 0.000
S91 Open wound of ankle and foot
0.726 0.274 0.000
K63.5 Polyp of colon
0.726 0.274 0.000
M90 Osteopathies in diseases classified elsewhere
0.725 0.274 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.724 0.276 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.723 0.277 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.723 0.277 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.722 0.278 0.000
K59.1 Functional diarrhoea
0.722 0.278 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.722 0.278 0.000
M25.74 Osteophyte (Hand)
0.721 0.279 0.000
I51.6 Cardiovascular disease, unspecified
0.721 0.279 0.000
M00-M03 Infectious arthropathies
0.720 0.280 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.719 0.281 0.000
F80-F89 Disorders of psychological development
0.719 0.281 0.000
M25.5 Pain in joint
0.719 0.281 0.000
S81 Open wound of lower leg
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I22.8 Subsequent myocardial infarction of other sites
0.716 0.284 0.000
K74 Fibrosis and cirrhosis of liver
0.716 0.284 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.715 0.285 0.000
K56.7 Ileus, unspecified
0.714 0.286 0.000
D55-D59 Haemolytic anaemias
0.714 0.286 0.000
I72.8 Aneurysm of other specified arteries
0.714 0.286 0.000
F60-F69 Disorders of adult personality and behaviour
0.713 0.287 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.713 0.287 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.713 0.287 0.000
I42 Cardiomyopathy
0.711 0.289 0.000
S92 Fracture of foot, except ankle
0.711 0.289 0.000
D53 Other nutritional anaemias
0.711 0.289 0.000
M15 Polyarthrosis
0.710 0.290 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.710 0.290 0.000
M33 Dermatopolymyositis
0.710 0.290 0.000
M32 Systemic lupus erythematosus
0.710 0.290 0.000
M30 Polyarteritis nodosa and related conditions
0.710 0.290 0.000
T87 Complications peculiar to reattachment and amputation
0.710 0.290 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.709 0.290 0.000
D50.1 Sideropenic dysphagia
0.709 0.290 0.000
W10 Fall on and from stairs and steps
0.709 0.291 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.709 0.291 0.000
I45 Other conduction disorders
0.708 0.291 0.000
I25.6 Silent myocardial ischaemia
0.708 0.292 0.000
I25.4 Coronary artery aneurysm
0.708 0.292 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.708 0.292 0.000
K75.8 Other specified inflammatory liver diseases
0.708 0.292 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.707 0.292 0.000
M91-M94 Chondropathies
0.707 0.293 0.000
K63.3 Ulcer of intestine
0.707 0.293 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.706 0.293 0.000
I25.1 Atherosclerotic heart disease
0.706 0.294 0.000
I44.2 Atrioventricular block, complete
0.706 0.294 0.000
K02.9 Dental caries, unspecified
0.705 0.295 0.000
I24 Other acute ischaemic heart diseases
0.705 0.295 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.704 0.296 0.000
Y35-Y36 Legal intervention and operations of war
0.704 0.296 0.000
Y10-Y34 Event of undetermined intent
0.704 0.296 0.000
Y00-Y09 Assault
0.704 0.296 0.000
X85-X99 Assault
0.704 0.296 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.704 0.296 0.000
X30-X39 Exposure to forces of nature
0.704 0.296 0.000
X20-X29 Contact with venomous animals and plants
0.704 0.296 0.000
X10-X19 Contact with heat and hot substances
0.704 0.296 0.000
X00-X09 Exposure to smoke, fire and flames
0.704 0.296 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.704 0.296 0.000
W75-W84 Other accidental threats to breathing
0.704 0.296 0.000
W65-W74 Accidental drowning and submersion
0.704 0.296 0.000
W50-W64 Exposure to animate mechanical forces
0.704 0.296 0.000
V98-V99 Other and unspecified transport accidents
0.704 0.296 0.000
V95-V97 Air and space transport accidents
0.704 0.296 0.000
V90-V94 Water transport accidents
0.704 0.296 0.000
V70-V79 Bus occupant injured in transport accident
0.704 0.296 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.704 0.296 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.704 0.296 0.000
V40-V49 Car occupant injured in transport accident
0.704 0.296 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.704 0.296 0.000
V20-V29 Motorcycle rider injured in transport accident
0.704 0.296 0.000
V01-V09 Pedestrian injured in transport accident
0.704 0.296 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.703 0.296 0.000
F31 Bipolar affective disorder
0.703 0.297 0.000
M86 Osteomyelitis
0.701 0.299 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.701 0.299 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.700 0.300 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.700 0.300 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.700 0.300 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.700 0.300 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.699 0.301 0.000
S80.0 Contusion of knee
0.699 0.301 0.000
K63.0 Abscess of intestine
0.698 0.302 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.698 0.302 0.000
M16.3 Other dysplastic coxarthrosis
0.697 0.302 0.000
Q00-Q07 Congenital malformations of the nervous system
0.697 0.303 0.000
K08.3 Retained dental root
0.696 0.304 0.000
H92 Otalgia and effusion of ear
0.696 0.304 0.000
M87.9 Osteonecrosis, unspecified
0.695 0.305 0.000
I52 Other heart disorders in diseases classified elsewhere
0.695 0.305 0.000
I48 Atrial fibrillation and flutter
0.695 0.305 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.695 0.305 0.000
I41 Myocarditis in diseases classified elsewhere
0.695 0.305 0.000
I40 Acute myocarditis
0.695 0.305 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.695 0.305 0.000
I37 Pulmonary valve disorders
0.695 0.305 0.000
I36 Nonrheumatic tricuspid valve disorders
0.695 0.305 0.000
I32 Pericarditis in diseases classified elsewhere
0.695 0.305 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.695 0.305 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.695 0.305 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.695 0.305 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.695 0.305 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.695 0.305 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.695 0.305 0.000
T36 Poisoning by systemic antibiotics
0.695 0.305 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.695 0.305 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.695 0.305 0.000
H55-H59 Other disorders of eye and adnexa
0.694 0.306 0.000
I51.4 Myocarditis, unspecified
0.691 0.308 0.000
M50.1 Cervical disk disorder with radiculopathy
0.691 0.309 0.000
M16.0 Primary coxarthrosis, bilateral
0.691 0.309 0.000
I21.4 Acute subendocardial myocardial infarction
0.690 0.310 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.689 0.311 0.000
M25.2 Flail joint
0.689 0.311 0.000
M25.1 Fistula of joint
0.689 0.311 0.000
M25.0 Haemarthrosis
0.689 0.311 0.000
K59.9 Functional intestinal disorder, unspecified
0.689 0.311 0.000
K25 Gastric ulcer
0.689 0.311 0.000
R26 Abnormalities of gait and mobility
0.688 0.312 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.688 0.312 0.000
Z96 Presence of other functional implants
0.688 0.312 0.000
I73.0 Raynaud's syndrome
0.687 0.313 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.685 0.314 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.685 0.314 0.000
M47.84 Other spondylosis (Thoracic region)
0.685 0.314 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.685 0.314 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.685 0.314 0.000
D64 Other anaemias
0.685 0.315 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.685 0.315 0.000
M47.89 Other spondylosis (Site unspecified)
0.684 0.316 0.000
S89 Other and unspecified injuries of lower leg
0.683 0.316 0.000
M25.4 Effusion of joint
0.683 0.317 0.000
H74 Other disorders of middle ear and mastoid
0.683 0.317 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.683 0.317 0.000
M50.3 Other cervical disk degeneration
0.683 0.317 0.000
T92 Sequelae of injuries of upper limb
0.683 0.317 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.683 0.317 0.000
Q80-Q89 Other congenital malformations
0.683 0.317 0.000
Q35-Q37 Cleft lip and cleft palate
0.683 0.317 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.683 0.317 0.000
H93 Other disorders of ear, not elsewhere classified
0.682 0.317 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.682 0.318 0.000
H81.0 Meniere's disease
0.682 0.318 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.680 0.320 0.000
I73.8 Other specified peripheral vascular diseases
0.679 0.321 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.679 0.321 0.000
H60-H62 Diseases of external ear
0.679 0.321 0.000
S88 Traumatic amputation of lower leg
0.679 0.321 0.000
S87 Crushing injury of lower leg
0.679 0.321 0.000
S86 Injury of muscle and tendon at lower leg level
0.679 0.321 0.000
S85 Injury of blood vessels at lower leg level
0.679 0.321 0.000
S84 Injury of nerves at lower leg level
0.679 0.321 0.000
Z91.5 Personal history of self-harm
0.679 0.321 0.000
V10-V19 Pedal cyclist injured in transport accident
0.679 0.321 0.000
I27.0 Primary pulmonary hypertension
0.678 0.322 0.000
I25.3 Aneurysm of heart
0.678 0.322 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.677 0.323 0.000
M20.1 Hallux valgus (acquired)
0.676 0.324 0.000
Y83.3 Surgical operation with formation of external stoma
0.676 0.324 0.000
Z81 Family history of mental and behavioural disorders
0.676 0.324 0.000
T86 Failure and rejection of transplanted organs and tissues
0.675 0.325 0.000
T90 Sequelae of injuries of head
0.675 0.325 0.000
K92.9 Disease of digestive system, unspecified
0.674 0.325 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.673 0.327 0.000
I44.3 Other and unspecified atrioventricular block
0.673 0.327 0.000
T66-T78 Other and unspecified effects of external causes
0.672 0.328 0.000
H91.9 Hearing loss, unspecified
0.672 0.328 0.000
W20-W49 Exposure to inanimate mechanical forces
0.671 0.329 0.000
Q51 Congenital malformations of uterus and cervix
0.670 0.330 0.000
M67 Other disorders of synovium and tendon
0.670 0.330 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.669 0.331 0.000
F33.9 Recurrent depressive disorder, unspecified
0.669 0.331 0.000
M45 Ankylosing spondylitis
0.669 0.331 0.000
M40-M43 Deforming dorsopathies
0.669 0.331 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.669 0.331 0.000
M14 Arthropathies in other diseases classified elsewhere
0.667 0.333 0.000
M12 Other specific arthropathies
0.667 0.333 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.667 0.333 0.000
M08 Juvenile arthritis
0.667 0.333 0.000
M19 Other arthrosis
0.667 0.333 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.667 0.333 0.000
M54.3 Sciatica
0.666 0.334 0.000
R29.6 Tendency to fall, not elsewhere classified
0.666 0.334 0.000
K77 Liver disorders in diseases classified elsewhere
0.665 0.334 0.000
K73 Chronic hepatitis, not elsewhere classified
0.665 0.334 0.000
K71 Toxic liver disease
0.665 0.334 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.665 0.335 0.000
Y84.2 Radiological procedure and radiotherapy
0.665 0.335 0.000
M53 Other dorsopathies, not elsewhere classified
0.664 0.336 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.664 0.336 0.000
M16.5 Other posttraumatic coxarthrosis
0.664 0.336 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.664 0.336 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.664 0.336 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.663 0.337 0.000
M25.37 Other instability of joint (Ankle and foot)
0.663 0.337 0.000
M31.9 Necrotising vasculopathy, unspecified
0.662 0.338 0.000
M31.8 Other specified necrotising vasculopathies
0.662 0.338 0.000
M31.7 Microscopic polyangiitis
0.662 0.338 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.662 0.338 0.000
M31.3 Wegener's granulomatosis
0.662 0.338 0.000
M31.2 Lethal midline granuloma
0.662 0.338 0.000
M31.1 Thrombotic microangiopathy
0.662 0.338 0.000
M31.0 Hypersensitivity angiitis
0.662 0.338 0.000
K56.2 Volvulus
0.662 0.338 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.662 0.338 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.660 0.340 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.660 0.340 0.000
I70 Atherosclerosis
0.660 0.340 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.659 0.341 0.000
F70-F79 Mental retardation
0.659 0.341 0.000
S14 Injury of nerves and spinal cord at neck level
0.658 0.342 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.657 0.342 0.000
H30-H36 Disorders of choroid and retina
0.657 0.343 0.000
K76.8 Other specified diseases of liver
0.657 0.343 0.000
M17.9 Gonarthrosis, unspecified
0.657 0.343 0.000
W18 Other fall on same level
0.657 0.343 0.000
W17 Other fall from one level to another
0.657 0.343 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.657 0.343 0.000
W15 Fall from cliff
0.657 0.343 0.000
W14 Fall from tree
0.657 0.343 0.000
W12 Fall on and from scaffolding
0.657 0.343 0.000
W11 Fall on and from ladder
0.657 0.343 0.000
W09 Fall involving playground equipment
0.657 0.343 0.000
W08 Fall involving other furniture
0.657 0.343 0.000
W05 Fall involving wheelchair
0.657 0.343 0.000
W04 Fall while being carried or supported by other persons
0.657 0.343 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.657 0.343 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.657 0.343 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.657 0.343 0.000
W00 Fall on same level involving ice and snow
0.657 0.343 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.655 0.345 0.000
K01 Embedded and impacted teeth
0.655 0.345 0.000
K76.9 Liver disease, unspecified
0.655 0.345 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.655 0.345 0.000
S80.7 Multiple superficial injuries of lower leg
0.654 0.346 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.654 0.346 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.653 0.347 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.653 0.347 0.000
K03 Other diseases of hard tissues of teeth
0.653 0.347 0.000
K00 Disorders of tooth development and eruption
0.653 0.347 0.000
I71 Aortic aneurysm and dissection
0.653 0.347 0.000
H66 Suppurative and unspecified otitis media
0.652 0.348 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.651 0.349 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.651 0.349 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.651 0.349 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.651 0.349 0.000
Q21 Congenital malformations of cardiac septa
0.650 0.349 0.000
G30-G32 Other degenerative diseases of the nervous system
0.650 0.350 0.000
M47.2 Other spondylosis with radiculopathy
0.650 0.350 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.650 0.350 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.650 0.350 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.649 0.350 0.000
H53-H54 Visual disturbances and blindness
0.649 0.351 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.649 0.351 0.000
D62 Acute posthaemorrhagic anaemia
0.648 0.352 0.000
M25.79 Osteophyte (Site unspecified)
0.647 0.352 0.000
M25.73 Osteophyte (Forearm)
0.647 0.352 0.000
M25.72 Osteophyte (Upper arm)
0.647 0.352 0.000
M25.70 Osteophyte (Multiple sites)
0.647 0.352 0.000
M54.9 Dorsalgia, unspecified
0.647 0.353 0.000
K59.4 Anal spasm
0.647 0.353 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.647 0.353 0.000
K59.8 Other specified functional intestinal disorders
0.647 0.353 0.000
I50.9 Heart failure, unspecified
0.647 0.353 0.000
S90 Superficial injury of ankle and foot
0.646 0.354 0.000
T39.1 4-Aminophenol derivatives
0.645 0.354 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.645 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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