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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17650376
log Bayes Factor = 5.4549
Chromosome 18   position 3,864,912  (GRCh37) Explore rs17650376 on Ensembl!
Variant rs17650376 is part of Cluster X0112

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
I30-I52 Other forms of heart disease
0.000 0.000 1.000
I35 Nonrheumatic aortic valve disorders
0.000 0.002 0.998
I35.0 Aortic (valve) stenosis
0.000 0.004 0.996
I20 Angina pectoris
0.000 0.004 0.996
I20.9 Angina pectoris, unspecified
0.000 0.005 0.995
I25.1 Atherosclerotic heart disease
0.000 0.005 0.995
I42 Cardiomyopathy
0.000 0.011 0.989
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.017 0.983
I25.2 Old myocardial infarction
0.000 0.026 0.974
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.054 0.946
I77 Other disorders of arteries and arterioles
0.000 0.061 0.939
I35.1 Aortic (valve) insufficiency
0.000 0.067 0.933
I42.2 Other hypertrophic cardiomyopathy
0.000 0.069 0.931
I21 Acute myocardial infarction
0.000 0.073 0.927
I50 Heart failure
0.000 0.081 0.919
I77.6 Arteritis, unspecified
0.000 0.089 0.911
I46 Cardiac arrest
0.000 0.089 0.911
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.092 0.908
I44 Atrioventricular and left bundle-branch block
0.000 0.096 0.904
I21.9 Acute myocardial infarction, unspecified
0.000 0.100 0.900
I77.1 Stricture of artery
0.000 0.106 0.894
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.125 0.875
I44.2 Atrioventricular block, complete
0.000 0.143 0.857
I50.1 Left ventricular failure
0.000 0.147 0.853
I27 Other pulmonary heart diseases
0.000 0.158 0.842
I51 Complications and ill-defined descriptions of heart disease
0.000 0.169 0.831
I05-I09 Chronic rheumatic heart diseases
0.000 0.180 0.820
I42.6 Alcoholic cardiomyopathy
0.000 0.182 0.818
I10-I15 Hypertensive diseases
0.000 0.199 0.801
I51.8 Other ill-defined heart diseases
0.000 0.203 0.797
I44.0 Atrioventricular block, first degree
0.000 0.205 0.795
I46.0 Cardiac arrest with successful resuscitation
0.000 0.207 0.793
I36 Nonrheumatic tricuspid valve disorders
0.000 0.210 0.790
I42.0 Dilated cardiomyopathy
0.000 0.217 0.783
I46.9 Cardiac arrest, unspecified
0.000 0.229 0.771
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.234 0.766
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.234 0.766
I73 Other peripheral vascular diseases
0.000 0.235 0.765
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.242 0.757
I25.5 Ischaemic cardiomyopathy
0.000 0.243 0.757
I44.3 Other and unspecified atrioventricular block
0.000 0.248 0.752
I27.0 Primary pulmonary hypertension
0.000 0.250 0.750
I42.8 Other cardiomyopathies
0.000 0.251 0.749
I70 Atherosclerosis
0.000 0.254 0.746
I42.9 Cardiomyopathy, unspecified
0.000 0.255 0.745
I23 Certain current complications following acute myocardial infarction
0.000 0.259 0.741
I33 Acute and subacute endocarditis
0.000 0.261 0.739
I77.8 Other specified disorders of arteries and arterioles
0.000 0.267 0.733
I27.9 Pulmonary heart disease, unspecified
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
I52 Other heart disorders in diseases classified elsewhere
0.000 0.283 0.717
I48 Atrial fibrillation and flutter
0.000 0.283 0.717
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.283 0.717
I41 Myocarditis in diseases classified elsewhere
0.000 0.283 0.717
I40 Acute myocarditis
0.000 0.283 0.717
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.283 0.717
I32 Pericarditis in diseases classified elsewhere
0.000 0.283 0.717
I11 Hypertensive heart disease
0.000 0.284 0.716
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.291 0.709
I42.5 Other restrictive cardiomyopathy
0.000 0.291 0.709
I42.4 Endocardial fibroelastosis
0.000 0.291 0.709
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.291 0.709
I25.4 Coronary artery aneurysm
0.000 0.298 0.702
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.307 0.693
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.308 0.692
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.310 0.690
I50.9 Heart failure, unspecified
0.000 0.311 0.689
I73.9 Peripheral vascular disease, unspecified
0.000 0.316 0.684
I77.5 Necrosis of artery
0.000 0.327 0.673
I77.4 Coeliac artery compression syndrome
0.000 0.327 0.673
I77.3 Arterial fibromuscular dysplasia
0.000 0.327 0.673
I37 Pulmonary valve disorders
0.000 0.328 0.672
I27.8 Other specified pulmonary heart diseases
0.000 0.328 0.672
I10 Essential (primary) hypertension
0.000 0.331 0.669
I77.0 Arteriovenous fistula, acquired
0.000 0.331 0.669
I51.9 Heart disease, unspecified
0.000 0.332 0.668
I21.4 Acute subendocardial myocardial infarction
0.000 0.333 0.667
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.335 0.665
I50.0 Congestive heart failure
0.000 0.335 0.665
I35.8 Other aortic valve disorders
0.000 0.342 0.658
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.345 0.655
I26 Pulmonary embolism
0.000 0.345 0.655
I46.1 Sudden cardiac death, so described
0.000 0.347 0.653
I28 Other diseases of pulmonary vessels
0.000 0.349 0.651
I44.5 Left posterior fascicular block
0.000 0.352 0.648
I44.4 Left anterior fascicular block
0.000 0.352 0.648
I30 Acute pericarditis
0.000 0.354 0.646
I08 Multiple valve diseases
0.000 0.354 0.646
I20.1 Angina pectoris with documented spasm
0.000 0.358 0.642
I51.4 Myocarditis, unspecified
0.000 0.359 0.641
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.359 0.641
I05 Rheumatic mitral valve diseases
0.000 0.360 0.640
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.369 0.631
I77.2 Rupture of artery
0.000 0.370 0.630
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.372 0.628
I27.1 Kyphoscoliotic heart disease
0.000 0.396 0.603
I45 Other conduction disorders
0.000 0.398 0.601
I72 Other aneurysm
0.000 0.402 0.598
I07 Rheumatic tricuspid valve diseases
0.000 0.402 0.597
I51.5 Myocardial degeneration
0.000 0.404 0.596
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.404 0.596
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.404 0.596
I09 Other rheumatic heart diseases
0.000 0.409 0.591
I06 Rheumatic aortic valve diseases
0.000 0.412 0.588
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.412 0.588
I20.0 Unstable angina
0.000 0.415 0.585
I73.8 Other specified peripheral vascular diseases
0.000 0.418 0.582
I05.9 Mitral valve disease, unspecified
0.000 0.420 0.580
I08.0 Disorders of both mitral and aortic valves
0.000 0.424 0.576
I13 Hypertensive heart and renal disease
0.000 0.426 0.574
I38 Endocarditis, valve unspecified
0.000 0.426 0.574
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.433 0.567
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.433 0.567
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.433 0.567
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.433 0.567
I51.6 Cardiovascular disease, unspecified
0.000 0.437 0.563
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.443 0.557
I23.8 Other current complications following acute myocardial infarction
0.000 0.444 0.556
I70.0 Atherosclerosis of aorta
0.000 0.444 0.556
I44.1 Atrioventricular block, second degree
0.000 0.446 0.554
I33.0 Acute and subacute infective endocarditis
0.000 0.447 0.553
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.448 0.552
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.450 0.550
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.451 0.549
I70.9 Generalised and unspecified atherosclerosis
0.000 0.465 0.535
I70.8 Atherosclerosis of other arteries
0.000 0.465 0.535
I70.1 Atherosclerosis of renal artery
0.000 0.465 0.535
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.468 0.531
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.468 0.531
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.468 0.531
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.468 0.531
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.468 0.531
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.468 0.531
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.468 0.531
I51.0 Cardiac septal defect, acquired
0.000 0.469 0.531
I33.9 Acute endocarditis, unspecified
0.000 0.470 0.530
I15 Secondary hypertension
0.000 0.477 0.523
I02 Rheumatic chorea
0.000 0.486 0.514
I01 Rheumatic fever with heart involvement
0.000 0.486 0.514
I00 Rheumatic fever without mention of heart involvement
0.000 0.486 0.514
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.486 0.514
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.486 0.514
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.486 0.514
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.486 0.514
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.486 0.514
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.486 0.514
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.486 0.514
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.486 0.514
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.486 0.514
I40.9 Acute myocarditis, unspecified
0.000 0.486 0.514
I40.8 Other acute myocarditis
0.000 0.486 0.514
I40.1 Isolated myocarditis
0.000 0.486 0.514
I40.0 Infective myocarditis
0.000 0.486 0.514
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.486 0.514
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.486 0.514
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.486 0.514
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.486 0.514
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.486 0.514
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.486 0.514
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.486 0.514
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.486 0.514
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.486 0.514
I48.4 Atypical atrial flutter
0.000 0.486 0.514
I48.3 Typical atrial flutter
0.000 0.486 0.514
I48.2 Chronic atrial fibrillation
0.000 0.486 0.514
I48.1 Persistent atrial fibrillation
0.000 0.486 0.514
I48.0 Paroxysmal atrial fibrillation
0.000 0.486 0.514
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.486 0.514
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.486 0.514
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.486 0.514
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.487 0.513
I27.2 Other secondary pulmonary hypertension
0.000 0.489 0.511
I78 Diseases of capillaries
0.000 0.489 0.511
I30.1 Infective pericarditis
0.000 0.490 0.510
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.493 0.507
I24 Other acute ischaemic heart diseases
0.000 0.494 0.506
I45.8 Other specified conduction disorders
0.000 0.500 0.500
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.501 0.499
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.505 0.495
I79.1 Aortitis in diseases classified elsewhere
0.000 0.505 0.495
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.505 0.495
I25.3 Aneurysm of heart
0.000 0.511 0.488
I37.9 Pulmonary valve disorder, unspecified
0.000 0.518 0.482
I37.8 Other pulmonary valve disorders
0.000 0.518 0.482
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.518 0.482
I37.0 Pulmonary valve stenosis
0.000 0.518 0.482
I44.6 Other and unspecified fascicular block
0.000 0.520 0.480
I34 Nonrheumatic mitral valve disorders
0.000 0.522 0.478
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.526 0.474
I05.2 Mitral stenosis with insufficiency
0.000 0.530 0.470
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.533 0.467
I28.8 Other specified diseases of pulmonary vessels
0.000 0.533 0.467
I28.1 Aneurysm of pulmonary artery
0.000 0.533 0.467
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.533 0.467
I30.8 Other forms of acute pericarditis
0.000 0.537 0.463
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.537 0.463
I08.9 Multiple valve disease, unspecified
0.000 0.537 0.463
I45.9 Conduction disorder, unspecified
0.000 0.539 0.461
I05.8 Other mitral valve diseases
0.000 0.541 0.459
I97.1 Other functional disturbances following cardiac surgery
0.000 0.544 0.456
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.547 0.452
I35.9 Aortic valve disorder, unspecified
0.001 0.549 0.450
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.551 0.449
I72.8 Aneurysm of other specified arteries
0.000 0.557 0.443
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.558 0.441
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.561 0.439
I07.1 Tricuspid insufficiency
0.000 0.562 0.438
I37.1 Pulmonary valve insufficiency
0.000 0.563 0.437
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.566 0.434
I72.4 Aneurysm of artery of lower extremity
0.000 0.568 0.432
I45.0 Right fascicular block
0.000 0.569 0.431
I72.0 Aneurysm of carotid artery
0.000 0.569 0.431
I72.9 Aneurysm of unspecified site
0.000 0.571 0.429
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.571 0.429
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.571 0.429
I72.1 Aneurysm of artery of upper extremity
0.000 0.571 0.429
I07.9 Tricuspid valve disease, unspecified
0.000 0.571 0.428
I07.8 Other tricuspid valve diseases
0.000 0.571 0.428
I07.2 Tricuspid stenosis with insufficiency
0.000 0.571 0.428
I07.0 Tricuspid stenosis
0.000 0.571 0.428
I09.9 Rheumatic heart disease, unspecified
0.000 0.574 0.426
I09.8 Other specified rheumatic heart diseases
0.000 0.576 0.424
I09.2 Chronic rheumatic pericarditis
0.000 0.576 0.424
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.576 0.424
I09.0 Rheumatic myocarditis
0.000 0.576 0.424
I45.4 Nonspecific intraventricular block
0.000 0.577 0.423
I45.3 Trifascicular block
0.000 0.578 0.422
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.578 0.422
I06.8 Other rheumatic aortic valve diseases
0.000 0.578 0.422
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.578 0.422
I06.1 Rheumatic aortic insufficiency
0.000 0.578 0.422
I06.0 Rheumatic aortic stenosis
0.000 0.578 0.422
I45.1 Other and unspecified right bundle-branch block
0.000 0.578 0.422
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.578 0.421
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.581 0.419
I71 Aortic aneurysm and dissection
0.000 0.584 0.416
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.588 0.412
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.588 0.412
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.588 0.412
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.588 0.412
I45.6 Preexcitation syndrome
0.000 0.591 0.409
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.593 0.407
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.601 0.398
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.606 0.394
I97.0 Postcardiotomy syndrome
0.000 0.606 0.394
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.616 0.384
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.616 0.384
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.616 0.384
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.616 0.384
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.616 0.384
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.616 0.384
I72.2 Aneurysm of renal artery
0.000 0.617 0.382
I45.2 Bifascicular block
0.000 0.618 0.381
I05.1 Rheumatic mitral insufficiency
0.000 0.621 0.379
I72.3 Aneurysm of iliac artery
0.000 0.623 0.376
I15.8 Other secondary hypertension
0.000 0.625 0.375
I15.2 Hypertension secondary to endocrine disorders
0.000 0.625 0.375
I15.0 Renovascular hypertension
0.000 0.625 0.375
I78.8 Other diseases of capillaries
0.000 0.625 0.375
I15.1 Hypertension secondary to other renal disorders
0.000 0.628 0.371
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.631 0.368
I01.8 Other acute rheumatic heart disease
0.000 0.631 0.368
I01.2 Acute rheumatic myocarditis
0.000 0.631 0.368
I01.1 Acute rheumatic endocarditis
0.000 0.631 0.368
I01.0 Acute rheumatic pericarditis
0.000 0.631 0.368
I02.9 Rheumatic chorea without heart involvement
0.000 0.631 0.368
I02.0 Rheumatic chorea with heart involvement
0.000 0.631 0.368
I78.9 Disease of capillaries, unspecified
0.000 0.633 0.366
I24.1 Dressler's syndrome
0.000 0.637 0.363
I73.0 Raynaud's syndrome
0.000 0.640 0.360
I05.0 Mitral stenosis
0.000 0.647 0.353
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.652 0.348
I24.8 Other forms of acute ischaemic heart disease
0.000 0.652 0.348
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.655 0.345
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.657 0.343
I20.8 Other forms of angina pectoris
0.000 0.659 0.341
I15.9 Seconday hypertension, unspecified
0.000 0.671 0.328
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.675 0.325
I95 Hypotension
0.000 0.678 0.322
I08.8 Other multiple valve diseases
0.000 0.679 0.321
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.680 0.319
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.686 0.314
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.689 0.311
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.689 0.311
I98.0 Cardiovascular syphilis
0.000 0.689 0.311
I47 Paroxysmal tachycardia
0.000 0.692 0.308
I30.9 Acute pericarditis, unspecified
0.001 0.694 0.306
I99 Other and unspecified disorders of circulatory system
0.000 0.694 0.306
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.701 0.299
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.701 0.298
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.701 0.298
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.701 0.298
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.701 0.298
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.708 0.292
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.715 0.285
I71.0 Dissection of aorta [any part]
0.000 0.715 0.285
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.715 0.285
I22 Subsequent myocardial infarction
0.001 0.721 0.278
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.722 0.278
I34.0 Mitral (valve) insufficiency
0.000 0.727 0.273
I95.8 Other hypotension
0.000 0.730 0.270
I12 Hypertensive renal disease
0.000 0.730 0.270
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.736 0.264
I45.5 Other specified heart block
0.001 0.738 0.262
I78.1 Naevus, nonneoplastic
0.000 0.739 0.261
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.741 0.259
I44.7 Left bundle-branch block, unspecified
0.000 0.748 0.252
I95.2 Hypotension due to drugs
0.000 0.754 0.246
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.761 0.239
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.768 0.232
I95.0 Idiopathic hypotension
0.000 0.769 0.231
I47.0 Reentry ventricular arrhythmia
0.000 0.783 0.217
I34.1 Mitral (valve) prolapse
0.000 0.783 0.217
I74 Arterial embolism and thrombosis
0.001 0.785 0.215
I31 Other diseases of pericardium
0.002 0.794 0.204
I22.8 Subsequent myocardial infarction of other sites
0.001 0.806 0.193
I51.7 Cardiomegaly
0.000 0.818 0.182
I22.0 Subsequent myocardial infarction of anterior wall
0.001 0.826 0.174
I74.8 Embolism and thrombosis of other arteries
0.001 0.845 0.154
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.001 0.845 0.154
I31.8 Other specified diseases of pericardium
0.001 0.852 0.146
I31.2 Haemopericardium, not elsewhere classified
0.001 0.852 0.146
I31.1 Chronic constrictive pericarditis
0.001 0.852 0.146
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.855 0.145
I74.0 Embolism and thrombosis of abdominal aorta
0.001 0.865 0.135
I74.9 Embolism and thrombosis of unspecified artery
0.001 0.865 0.134
I31.0 Chronic adhesive pericarditis
0.002 0.871 0.127
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.001 0.875 0.124
I95.9 Hypotension, unspecified
0.000 0.881 0.119
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.001 0.882 0.117
I47.1 Supraventricular tachycardia
0.000 0.887 0.113
I95.1 Orthostatic hypotension
0.000 0.887 0.113
I22.9 Subsequent myocardial infarction of unspecified site
0.001 0.889 0.110
I22.1 Subsequent myocardial infarction of inferior wall
0.001 0.890 0.109
I74.5 Embolism and thrombosis of iliac artery
0.001 0.894 0.105
I12.0 Hypertensive renal disease with renal failure
0.000 0.894 0.106
I12.9 Hypertensive renal disease without renal failure
0.001 0.907 0.092
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.912 0.088
I86 Varicose veins of other sites
0.000 0.932 0.068
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.933 0.067
I88 Nonspecific lymphadenitis
0.000 0.934 0.066
I47.2 Ventricular tachycardia
0.000 0.937 0.063
I49 Other cardiac arrhythmias
0.000 0.942 0.058
I31.9 Disease of pericardium, unspecified
0.002 0.943 0.055
I83 Varicose veins of lower extremities
0.000 0.945 0.055
C77.0 Lymph nodes of head, face and neck
0.054 0.946 0.000
I81 Portal vein thrombosis
0.000 0.946 0.054
I85 Oesophageal varices
0.000 0.947 0.053
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.948 0.052
I86.4 Gastric varices
0.000 0.948 0.052
I86.8 Varicose veins of other specified sites
0.000 0.948 0.051
I82 Other venous embolism and thrombosis
0.000 0.949 0.051
I89.1 Lymphangitis
0.000 0.950 0.050
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.950 0.050
I86.3 Vulval varices
0.000 0.951 0.049
I86.2 Pelvic varices
0.000 0.951 0.049
I86.0 Sublingual varices
0.000 0.951 0.049
I86.1 Scrotal varices
0.000 0.952 0.048
I89.0 Lymphoedema, not elsewhere classified
0.000 0.952 0.048
I88.8 Other nonspecific lymphadenitis
0.000 0.953 0.047
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.953 0.047
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.953 0.047
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.953 0.047
I60-I69 Cerebrovascular diseases
0.044 0.953 0.002
I65.2 Occlusion and stenosis of carotid artery
0.046 0.954 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.045 0.954 0.001
I49.8 Other specified cardiac arrhythmias
0.000 0.954 0.046
I80 Phlebitis and thrombophlebitis
0.000 0.956 0.044
I87 Other disorders of veins
0.000 0.956 0.044
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.957 0.043
I61 Intracerebral haemorrhage
0.042 0.958 0.001
I60 Subarachnoid haemorrhage
0.042 0.958 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.958 0.042
I49.2 Junctional premature depolarisation
0.000 0.958 0.042
I49.4 Other and unspecified premature depolarisation
0.000 0.959 0.041
I61.9 Intracerebral haemorrhage, unspecified
0.041 0.959 0.000
I31.3 Pericardial effusion (noninflammatory)
0.002 0.960 0.038
N81.4 Uterovaginal prolapse, unspecified
0.040 0.960 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.962 0.038
I60.9 Subarachnoid haemorrhage, unspecified
0.038 0.962 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.962 0.038
I64 Stroke, not specified as haemorrhage or infarction
0.037 0.963 0.000
I82.3 Embolism and thrombosis of renal vein
0.000 0.963 0.037
I82.1 Thrombophlebitis migrans
0.000 0.963 0.037
I82.0 Budd-Chiari syndrome
0.000 0.963 0.037
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.037 0.963 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.036 0.963 0.001
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.965 0.035
I63 Cerebral infarction
0.035 0.965 0.000
I82.2 Embolism and thrombosis of vena cava
0.000 0.966 0.034
I61.8 Other intracerebral haemorrhage
0.034 0.966 0.000
N81.3 Complete uterovaginal prolapse
0.034 0.966 0.000
I85.0 Oesophageal varices with bleeding
0.000 0.966 0.034
N81 Female genital prolapse
0.034 0.966 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.034 0.966 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.032 0.966 0.002
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.032 0.966 0.002
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.967 0.033
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.033 0.967 0.001
I65.8 Occlusion and stenosis of other precerebral artery
0.033 0.967 0.001
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.033 0.967 0.001
I65.1 Occlusion and stenosis of basilar artery
0.033 0.967 0.001
N81.1 Cystocele
0.033 0.967 0.000
I63.8 Other cerebral infarction
0.033 0.967 0.000
I85.9 Oesophageal varices without bleeding
0.000 0.967 0.032
I87.9 Disorder of vein, unspecified
0.000 0.968 0.031
I87.0 Postphlebitic syndrome
0.000 0.968 0.031
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.968 0.032
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.031 0.969 0.001
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.031 0.969 0.000
I82.8 Embolism and thrombosis of other specified veins
0.000 0.969 0.031
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.030 0.969 0.001
I61.6 Intracerebral haemorrhage, multiple localised
0.030 0.969 0.001
I61.3 Intracerebral haemorrhage in brain stem
0.030 0.969 0.001
I60.5 Subarachnoid haemorrhage from vertebral artery
0.030 0.969 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.030 0.969 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.030 0.969 0.000
I87.8 Other specified disorders of veins
0.000 0.970 0.030
N81.9 Female genital prolapse, unspecified
0.030 0.970 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.029 0.970 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.029 0.971 0.001
I62 Other nontraumatic intracranial haemorrhage
0.028 0.971 0.001
I61.4 Intracerebral haemorrhage in cerebellum
0.028 0.971 0.001
I49.0 Ventricular fibrillation and flutter
0.000 0.971 0.028
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.028 0.972 0.000
I67 Other cerebrovascular diseases
0.027 0.972 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.028 0.972 0.000
I60.8 Other subarachnoid haemorrhage
0.027 0.972 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.973 0.027
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.027 0.973 0.000
I87.1 Compression of vein
0.000 0.974 0.026
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.974 0.026
I49.3 Ventricular premature depolarisation
0.000 0.974 0.026
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.025 0.975 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.025 0.975 0.000
I67.9 Cerebrovascular disease, unspecified
0.025 0.975 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.025 0.975 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.025 0.975 0.000
I49.1 Atrial premature depolarisation
0.001 0.975 0.024
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.024 0.975 0.001
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.023 0.976 0.001
I66.8 Occlusion and stenosis of other cerebral artery
0.023 0.976 0.001
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.023 0.976 0.001
I66.3 Occlusion and stenosis of cerebellar arteries
0.023 0.976 0.001
I66.2 Occlusion and stenosis of posterior cerebral artery
0.023 0.976 0.001
I66.1 Occlusion and stenosis of anterior cerebral artery
0.023 0.976 0.001
I66.0 Occlusion and stenosis of middle cerebral artery
0.023 0.976 0.001
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.023 0.976 0.001
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.023 0.976 0.001
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.023 0.976 0.001
I68.0 Cerebral amyloid angiopathy
0.023 0.976 0.001
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.976 0.024
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.976 0.024
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.024 0.976 0.000
N81.0 Female urethrocele
0.023 0.977 0.000
N81.5 Vaginal enterocele
0.022 0.978 0.000
I62.1 Nontraumatic extradural haemorrhage
0.020 0.979 0.001
I69 Sequelae of cerebrovascular disease
0.020 0.979 0.001
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.020 0.979 0.001
I67.1 Cerebral aneurysm, nonruptured
0.020 0.980 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.020 0.980 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.020 0.980 0.000
I67.5 Moyamoya disease
0.020 0.980 0.000
I67.4 Hypertensive encephalopathy
0.020 0.980 0.000
I67.3 Progressive vascular leukoencephalopathy
0.020 0.980 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.980 0.020
N81.2 Incomplete uterovaginal prolapse
0.019 0.981 0.000
I67.2 Cerebral atherosclerosis
0.017 0.982 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.017 0.982 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.015 0.983 0.001
I67.0 Dissection of cerebral arteries, nonruptured
0.016 0.983 0.001
G47.9 Sleep disorder, unspecified
0.000 0.984 0.016
I49.5 Sick sinus syndrome
0.001 0.984 0.016
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.000 0.984 0.016
G47 Sleep disorders
0.000 0.984 0.016
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.015 0.985 0.001
C16.0 Cardia
0.015 0.985 0.000
N81.8 Other female genital prolapse
0.015 0.985 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.014 0.985 0.001
C16.9 Stomach, unspecified
0.014 0.986 0.000
C16 Malignant neoplasm of stomach
0.014 0.986 0.000
G47.3 Sleep apnoea
0.000 0.986 0.014
I69.0 Sequelae of subarachnoid haemorrhage
0.013 0.986 0.001
I49.9 Cardiac arrhythmia, unspecified
0.000 0.987 0.013
G47.1 Disorders of excessive somnolence [hypersomnias]
0.000 0.987 0.013
G47.4 Narcolepsy and cataplexy
0.000 0.988 0.012
C77.8 Lymph nodes of multiple regions
0.012 0.988 0.000
C90.0 Multiple myeloma
0.012 0.988 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.012 0.988 0.000
C16.5 Lesser curvature of stomach, unspecified
0.012 0.988 0.000
G47.2 Disorders of the sleep-wake schedule
0.000 0.988 0.012
C16.2 Body of stomach
0.011 0.989 0.000
I69.3 Sequelae of cerebral infarction
0.010 0.989 0.001
C16.3 Pyloric antrum
0.011 0.989 0.000
G47.8 Other sleep disorders
0.000 0.989 0.011
C16.6 Greater curvature of stomach, unspecified
0.011 0.989 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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