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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17720293
log Bayes Factor = 161.024
Chromosome 6   position 28,214,698  (GRCh37) Explore rs17720293 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.999 0.000 0.001
N40 Hyperplasia of prostate
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
K70-K77 Diseases of liver
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.998 0.001 0.001
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.999 0.001 0.000
K75 Other inflammatory liver diseases
0.999 0.001 0.000
M35 Other systemic involvement of connective tissue
0.999 0.001 0.000
K75.4 Autoimmune hepatitis
0.998 0.002 0.000
E10.3 With ophthalmic complications
0.998 0.002 0.000
M35.0 Sicca syndrome [Sjogren]
0.997 0.003 0.000
E20-E35 Disorders of other endocrine glands
0.997 0.003 0.000
H36 Retinal disorders in diseases classified elsewhere
0.997 0.003 0.000
E27 Other disorders of adrenal gland
0.997 0.003 0.000
E27.1 Primary adrenocortical insufficiency
0.996 0.004 0.000
H36.0 Diabetic retinopathy
0.995 0.005 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.992 0.008 0.000
E83.1 Disorders of iron metabolism
0.000 0.008 0.992
D60-D64 Aplastic and other anaemias
0.992 0.008 0.000
E14 Unspecified diabetes mellitus
0.991 0.009 0.000
E11 Non-insulin-dependent diabetes mellitus
0.991 0.009 0.000
D64 Other anaemias
0.991 0.009 0.000
D64.9 Anaemia, unspecified
0.991 0.009 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.988 0.012 0.000
M05-M14 Inflammatory polyarthropathies
0.983 0.017 0.000
D80-D89 Certain disorders involving the immune mechanism
0.981 0.019 0.000
M20.1 Hallux valgus (acquired)
0.000 0.019 0.981
L20-L30 Dermatitis and eczema
0.979 0.021 0.000
E11.3 With ophthalmic complications
0.973 0.027 0.000
E10.1 With ketoacidosis
0.972 0.028 0.000
H34 Retinal vascular occlusions
0.969 0.031 0.000
L30 Other dermatitis
0.969 0.031 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.032 0.968
E14.3 With ophthalmic complications
0.963 0.037 0.000
K40 Inguinal hernia
0.000 0.040 0.960
L30.9 Dermatitis, unspecified
0.960 0.040 0.000
K35-K38 Diseases of appendix
0.959 0.040 0.000
M20 Acquired deformities of fingers and toes
0.003 0.045 0.952
K35 Acute appendicitis
0.952 0.048 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.951 0.049 0.000
D86 Sarcoidosis
0.951 0.049 0.000
K35.9 Acute appendicitis, unspecified
0.949 0.051 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.949 0.051 0.000
K40-K46 Hernia
0.003 0.054 0.943
M15-M19 Arthrosis
0.945 0.055 0.000
K44 Diaphragmatic hernia
0.001 0.057 0.942
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.057 0.943
E10.2 With renal complications
0.943 0.057 0.000
H43-H45 Disorders of vitreous body and globe
0.940 0.060 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.061 0.938
E11.5 With peripheral circulatory complications
0.936 0.064 0.000
L50-L54 Urticaria and erythema
0.933 0.067 0.000
M17 Gonarthrosis [arthrosis of knee]
0.931 0.069 0.000
M17.9 Gonarthrosis, unspecified
0.927 0.073 0.000
M34 Systemic sclerosis
0.926 0.074 0.000
H34.8 Other retinal vascular occlusions
0.924 0.076 0.000
K72 Hepatic failure, not elsewhere classified
0.921 0.079 0.000
N40-N51 Diseases of male genital organs
0.000 0.080 0.920
D86.9 Sarcoidosis, unspecified
0.920 0.080 0.000
M23 Internal derangement of knee
0.917 0.083 0.000
N42 Other disorders of prostate
0.000 0.084 0.916
M07 Psoriatic and enteropathic arthropathies
0.915 0.085 0.000
K73 Chronic hepatitis, not elsewhere classified
0.914 0.086 0.000
K75.9 Inflammatory liver disease, unspecified
0.912 0.088 0.000
M22 Disorders of patella
0.912 0.088 0.000
K75.8 Other specified inflammatory liver diseases
0.909 0.091 0.000
H43 Disorders of vitreous body
0.903 0.097 0.000
E11.9 Without complications
0.902 0.098 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.901 0.099 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.899 0.101 0.000
H02 Other disorders of eyelid
0.899 0.101 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.102 0.898
M31 Other necrotising vasculopathies
0.895 0.105 0.000
M20.4 Other hammer toe(s) (acquired)
0.000 0.109 0.891
H43.1 Vitreous haemorrhage
0.890 0.110 0.000
K90.9 Intestinal malabsorption, unspecified
0.889 0.111 0.000
H53-H54 Visual disturbances and blindness
0.886 0.114 0.000
H02.5 Other disorders affecting eyelid function
0.884 0.116 0.000
H35 Other retinal disorders
0.875 0.125 0.000
N42.8 Other specified disorders of prostate
0.000 0.125 0.875
M65-M68 Disorders of synovium and tendon
0.871 0.129 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.870 0.130 0.000
E14.9 Without complications
0.870 0.130 0.000
N30-N39 Other diseases of urinary system
0.000 0.132 0.868
N39 Other disorders of urinary system
0.000 0.132 0.868
M07.3 Other psoriatic arthropathies
0.866 0.134 0.000
E10.5 With peripheral circulatory complications
0.861 0.139 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.861 0.139 0.000
H35.8 Other specified retinal disorders
0.856 0.144 0.000
H02.1 Ectropion of eyelid
0.856 0.144 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.148 0.852
M60-M63 Disorders of muscles
0.852 0.148 0.000
L52 Erythema nodosum
0.852 0.148 0.000
N32 Other disorders of bladder
0.000 0.149 0.851
L27 Dermatitis due to substances taken internally
0.850 0.150 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.850 0.150 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.849 0.151 0.000
N32.0 Bladder-neck obstruction
0.000 0.152 0.848
E16.0 Drug-induced hypoglycaemia without coma
0.848 0.152 0.000
H05 Disorders of orbit
0.846 0.154 0.000
M11 Other crystal arthropathies
0.845 0.155 0.000
N39.0 Urinary tract infection, site not specified
0.000 0.156 0.844
H54 Blindness and low vision
0.840 0.160 0.000
L10-L14 Bullous disorders
0.838 0.162 0.000
E10.4 With neurological complications
0.838 0.162 0.000
N39.8 Other specified disorders of urinary system
0.000 0.165 0.835
S40-S49 Injuries to the shoulder and upper arm
0.831 0.169 0.000
N36 Other disorders of urethra
0.000 0.172 0.828
N39.3 Stress incontinence
0.000 0.173 0.827
K72.0 Acute and subacute hepatic failure
0.826 0.174 0.000
Q50-Q56 Congenital malformations of genital organs
0.825 0.175 0.000
M35.1 Other overlap syndromes
0.824 0.176 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.823 0.177 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.821 0.179 0.000
L28 Lichen simplex chronicus and prurigo
0.820 0.180 0.000
M31.6 Other giant cell arteritis
0.819 0.181 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.819 0.181 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.181 0.819
D50-D53 Nutritional anaemias
0.819 0.181 0.000
M67 Other disorders of synovium and tendon
0.816 0.184 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.816 0.184 0.000
E50-E64 Other nutritional deficiencies
0.815 0.185 0.000
M13 Other arthritis
0.815 0.185 0.000
D83 Common variable immunodeficiency
0.812 0.188 0.000
E11.6 With other specified complications
0.811 0.189 0.000
S90-S99 Injuries to the ankle and foot
0.809 0.191 0.000
M34.1 CR(E)ST syndrome
0.809 0.191 0.000
D55-D59 Haemolytic anaemias
0.805 0.194 0.000
H34.2 Other retinal artery occlusions
0.805 0.195 0.000
E20 Hypoparathyroidism
0.805 0.195 0.000
H02.6 Xanthelasma of eyelid
0.804 0.196 0.000
M10 Gout
0.804 0.196 0.000
M22.3 Other derangements of patella
0.801 0.199 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.801 0.199 0.000
E10.0 With coma
0.800 0.200 0.000
S46.2 Injury of muscle and tendon of other parts of biceps
0.796 0.204 0.000
M22.8 Other disorders of patella
0.795 0.205 0.000
S00-S09 Injuries to the head
0.793 0.207 0.000
N34 Urethritis and urethral syndrome
0.000 0.208 0.792
N36.2 Urethral caruncle
0.000 0.209 0.791
S20-S29 Injuries to the thorax
0.791 0.209 0.000
H25-H28 Disorders of lens
0.790 0.210 0.000
L53 Other erythematous conditions
0.787 0.213 0.000
M18 Arthrosis of first carpometacarpal joint
0.787 0.213 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.785 0.215 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.784 0.216 0.000
M25 Other joint disorders, not elsewhere classified
0.784 0.216 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.782 0.218 0.000
H46 Optic neuritis
0.782 0.218 0.000
I77 Other disorders of arteries and arterioles
0.781 0.219 0.000
M13.0 Polyarthritis, unspecified
0.780 0.220 0.000
S02 Fracture of skull and facial bones
0.778 0.222 0.000
I73 Other peripheral vascular diseases
0.776 0.224 0.000
E24 Cushing's syndrome
0.775 0.225 0.000
M34.9 Systemic sclerosis, unspecified
0.775 0.225 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.773 0.227 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.772 0.228 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.771 0.229 0.000
E10.6 With other specified complications
0.771 0.229 0.000
Chapter XIV Diseases of the genitourinary system
0.005 0.230 0.765
M67.8 Other specified disorders of synovium and tendon
0.769 0.231 0.000
L94 Other localised connective tissue disorders
0.767 0.233 0.000
H31 Other disorders of choroid
0.767 0.233 0.000
K72.9 Hepatic failure, unspecified
0.767 0.233 0.000
L30.8 Other specified dermatitis
0.766 0.233 0.000
Chapter II Neoplasms
0.764 0.236 0.000
M23.3 Other meniscus derangements
0.763 0.237 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.238 0.762
S02.4 Fracture of malar and maxillary bones
0.761 0.239 0.000
E14.1 With ketoacidosis
0.761 0.239 0.000
Chapter IX Diseases of the circulatory system
0.760 0.240 0.000
E14.5 With peripheral circulatory complications
0.759 0.241 0.000
M23.9 Internal derangement of knee, unspecified
0.759 0.241 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.757 0.243 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.001 0.243 0.756
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.756 0.244 0.000
H54.4 Blindness, one eye
0.756 0.244 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.755 0.245 0.000
H30 Chorioretinal inflammation
0.755 0.245 0.000
M62 Other disorders of muscle
0.754 0.246 0.000
C15-C26 Malignant neoplasms of digestive organs
0.754 0.246 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.753 0.247 0.000
E10.8 With unspecified complications
0.753 0.247 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.751 0.249 0.000
D50 Iron deficiency anaemia
0.751 0.249 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.751 0.249 0.000
I73.9 Peripheral vascular disease, unspecified
0.750 0.250 0.000
M15 Polyarthrosis
0.750 0.250 0.000
D80 Immunodeficiency with predominantly antibody defects
0.750 0.250 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.750 0.250 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.750 0.250 0.000
E14.6 With other specified complications
0.750 0.250 0.000
M86-M90 Other osteopathies
0.749 0.251 0.000
E14.2 Withrenal complications
0.749 0.251 0.000
M14 Arthropathies in other diseases classified elsewhere
0.748 0.252 0.000
M11.2 Other chondrocalcinosis
0.747 0.253 0.000
H34.1 Central retinal artery occlusion
0.744 0.255 0.000
I77.6 Arteritis, unspecified
0.744 0.256 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.744 0.256 0.000
I74 Arterial embolism and thrombosis
0.743 0.257 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.743 0.257 0.000
M32 Systemic lupus erythematosus
0.741 0.259 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.740 0.260 0.000
S09 Other and unspecified injuries of head
0.740 0.260 0.000
M12 Other specific arthropathies
0.739 0.260 0.000
M22.2 Patellofemoral disorders
0.739 0.261 0.000
C18 Malignant neoplasm of colon
0.738 0.262 0.000
M06 Other rheumatoid arthritis
0.737 0.263 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.737 0.263 0.000
M25.9 Joint disorder, unspecified
0.736 0.264 0.000
M00-M03 Infectious arthropathies
0.735 0.265 0.000
S20 Superficial injury of thorax
0.733 0.267 0.000
E05.8 Other thyrotoxicosis
0.733 0.267 0.000
C25 Malignant neoplasm of pancreas
0.733 0.267 0.000
C18.9 Colon, unspecified
0.732 0.268 0.000
H05.0 Acute inflammation of orbit
0.730 0.270 0.000
D84 Other immunodeficiencies
0.728 0.272 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.728 0.272 0.000
E27.2 Addisonian crisis
0.727 0.273 0.000
I77.1 Stricture of artery
0.727 0.273 0.000
M35.7 Hypermobility syndrome
0.727 0.273 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.726 0.274 0.000
S21 Open wound of thorax
0.724 0.276 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.724 0.276 0.000
M91-M94 Chondropathies
0.724 0.276 0.000
N34.2 Other urethritis
0.000 0.278 0.722
M35.3 Polymyalgia rheumatica
0.720 0.280 0.000
L40-L45 Papulosquamous disorders
0.720 0.280 0.000
D86.8 Sarcoidosis of other and combined sites
0.720 0.280 0.000
T00-T07 Injuries involving multiple body regions
0.720 0.280 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.719 0.281 0.000
M34.8 Other forms of systemic sclerosis
0.719 0.281 0.000
K90.8 Other intestinal malabsorption
0.718 0.282 0.000
N36.3 Prolapsed urethral mucosa
0.000 0.282 0.718
E16.1 Other hypoglycaemia
0.718 0.282 0.000
K35.2 Acute appendicitis with generalized peritonitis
0.717 0.282 0.000
D86.0 Sarcoidosis of lung
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
L50 Urticaria
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
S93.0 Dislocation of ankle joint
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.716 0.284 0.000
K77 Liver disorders in diseases classified elsewhere
0.716 0.284 0.000
K71 Toxic liver disease
0.716 0.284 0.000
H35.2 Other proliferative retinopathy
0.716 0.284 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.716 0.284 0.001
K75.3 Granulomatous hepatitis, not elsewhere classified
0.716 0.284 0.000
K75.2 Nonspecific reactive hepatitis
0.716 0.284 0.000
K75.1 Phlebitis of portal vein
0.716 0.284 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.716 0.284 0.000
M35.8 Other specified systemic involvement of connective tissue
0.716 0.284 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.716 0.284 0.000
M35.5 Multifocal fibrosclerosis
0.716 0.284 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.716 0.284 0.000
E11.0 With coma
0.716 0.284 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.715 0.285 0.000
E32 Diseases of thymus
0.715 0.285 0.000
E31 Polyglandular dysfunction
0.715 0.285 0.000
E30 Disorders of puberty, not elsewhere classified
0.715 0.285 0.000
E25 Adrenogenital disorders
0.715 0.285 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.715 0.285 0.000
E27.5 Adrenomedullary hyperfunction
0.715 0.285 0.000
E27.0 Other adrenocortical overactivity
0.715 0.285 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.713 0.287 0.000
E14.4 With neurological complications
0.713 0.287 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.711 0.289 0.000
E14.8 With unspecified complications
0.711 0.289 0.000
E14.7 With multiple complications
0.711 0.289 0.000
E14.0 With coma
0.711 0.289 0.000
M33 Dermatopolymyositis
0.711 0.289 0.000
L20 Atopic dermatitis
0.710 0.289 0.000
E11.7 With multiple complications
0.710 0.289 0.000
D64.4 Congenital dyserythropoietic anaemia
0.710 0.290 0.000
D64.3 Other sideroblastic anaemias
0.710 0.290 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.710 0.290 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.710 0.290 0.000
D64.0 Hereditary sideroblastic anaemia
0.710 0.290 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.710 0.290 0.000
Chapter XX External causes of morbidity and mortality
0.710 0.290 0.000
L23 Allergic contact dermatitis
0.709 0.291 0.000
H54.7 Unspecified visual loss
0.709 0.291 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.708 0.292 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.708 0.292 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.708 0.292 0.000
D86.3 Sarcoidosis of skin
0.707 0.293 0.000
K46 Unspecified abdominal hernia
0.002 0.293 0.705
K36 Other appendicitis
0.705 0.294 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.705 0.295 0.000
M17.1 Other primary gonarthrosis
0.705 0.295 0.000
E27.9 Disorder of adrenal gland, unspecified
0.705 0.295 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.705 0.295 0.000
M08 Juvenile arthritis
0.705 0.295 0.000
L13 Other bullous disorders
0.705 0.295 0.000
E07 Other disorders of thyroid
0.704 0.296 0.000
D82 Immunodeficiency associated with other major defects
0.703 0.297 0.000
D81 Combined immunodeficiencies
0.703 0.297 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.703 0.297 0.000
H34.9 Retinal vascular occlusion, unspecified
0.702 0.298 0.000
M70-M79 Other soft tissue disorders
0.702 0.298 0.000
L25 Unspecified contact dermatitis
0.702 0.298 0.000
L24 Irritant contact dermatitis
0.702 0.298 0.000
L26 Exfoliative dermatitis
0.702 0.298 0.000
L22 Diaper [napkin] dermatitis
0.702 0.298 0.000
L93 Lupus erythematosus
0.701 0.299 0.000
H26 Other cataract
0.700 0.300 0.000
H04 Disorders of lachrymal system
0.699 0.301 0.000
D50.9 Iron deficiency anaemia, unspecified
0.699 0.301 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.301 0.698
C25.9 Pancreas, unspecified
0.697 0.303 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.697 0.303 0.000
S09.9 Unspecified injury of head
0.696 0.304 0.000
H34.0 Transient retinal artery occlusion
0.695 0.305 0.000
L30.5 Pityriasis alba
0.695 0.305 0.000
L30.4 Erythema intertrigo
0.695 0.305 0.000
L30.3 Infective dermatitis
0.695 0.305 0.000
L30.2 Cutaneous autosensitisation
0.695 0.305 0.000
L30.1 Dyshidrosis [pompholyx]
0.695 0.305 0.000
L30.0 Nummular dermatitis
0.695 0.305 0.000
M72 Fibroblastic disorders
0.694 0.306 0.000
M10.0 Idiopathic gout
0.694 0.306 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.694 0.306 0.000
M86 Osteomyelitis
0.693 0.307 0.000
D83.9 Common variable immunodeficiency, unspecified
0.692 0.308 0.000
S02.3 Fracture of orbital floor
0.691 0.309 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.691 0.309 0.000
L92.0 Granuloma annulare
0.690 0.309 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.690 0.310 0.000
Q51 Congenital malformations of uterus and cervix
0.690 0.310 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.690 0.310 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.311 0.688
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.311 0.688
H54.6 Unqualified visual loss, one eye
0.688 0.312 0.000
M23.1 Discoid meniscus (congenital)
0.687 0.313 0.000
H26.9 Cataract, unspecified
0.687 0.313 0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level
0.687 0.313 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.685 0.315 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.684 0.316 0.000
T79-T79 Certain early complications of trauma
0.684 0.316 0.000
C85.1 B-cell lymphoma, unspecified
0.684 0.316 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.682 0.318 0.000
N42.0 Calculus of prostate
0.000 0.318 0.682
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.682 0.318 0.000
H35.4 Peripheral retinal degeneration
0.680 0.320 0.000
Q53 Undescended testicle
0.680 0.320 0.000
S92 Fracture of foot, except ankle
0.680 0.320 0.000
L28.0 Lichen simplex chronicus
0.679 0.321 0.000
S20.2 Contusion of thorax
0.679 0.321 0.000
M23.0 Cystic meniscus
0.678 0.322 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.678 0.322 0.000
E29 Testicular dysfunction
0.677 0.323 0.000
E23 Hypofunction and other disorders of pituitary gland
0.677 0.323 0.000
K44.1 Diaphragmatic hernia with gangrene
0.001 0.324 0.675
M35.2 Behcet's disease
0.676 0.324 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.676 0.324 0.000
D86.1 Sarcoidosis of lymph nodes
0.676 0.324 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.675 0.325 0.000
S93.1 Dislocation of toe(s)
0.675 0.325 0.000
E61 Deficiency of other nutrient elements
0.675 0.325 0.000
M23.4 Loose body in knee
0.675 0.325 0.000
E03.8 Other specified hypothyroidism
0.674 0.326 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.674 0.326 0.000
N39.9 Disorder of urinary system, unspecified
0.000 0.326 0.674
H01 Other inflammation of eyelid
0.673 0.327 0.000
H27 Other disorders of lens
0.673 0.327 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.673 0.327 0.000
C81 Hodgkin's disease
0.671 0.329 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.670 0.330 0.000
L53.8 Other specified erythematous conditions
0.670 0.330 0.000
K73.9 Chronic hepatitis, unspecified
0.669 0.331 0.000
L54 Erythema in diseases classified elsewhere
0.669 0.331 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.668 0.332 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.668 0.332 0.000
C07 Malignant neoplasm of parotid gland
0.668 0.332 0.000
L89 Decubitus ulcer
0.668 0.332 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.667 0.333 0.000
E20.9 Hypoparathyroidism, unspecified
0.667 0.333 0.000
H05.8 Other disorders of orbit
0.666 0.333 0.000
E13 Other specified diabetes mellitus
0.666 0.334 0.000
Q00-Q07 Congenital malformations of the nervous system
0.665 0.335 0.000
C23 Malignant neoplasm of gallbladder
0.665 0.335 0.000
H02.2 Lagophthalmos
0.664 0.336 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.664 0.336 0.000
M34.0 Progressive systemic sclerosis
0.664 0.336 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.663 0.337 0.000
V20-V29 Motorcycle rider injured in transport accident
0.662 0.338 0.000
M06.9 Rheumatoid arthritis, unspecified
0.662 0.338 0.000
M62.8 Other specified disorders of muscle
0.661 0.339 0.000
M30 Polyarteritis nodosa and related conditions
0.661 0.339 0.000
S46.3 Injury of muscle and tendon of triceps
0.661 0.339 0.000
K72.1 Chronic hepatic failure
0.660 0.340 0.000
N36.9 Urethral disorder, unspecified
0.000 0.340 0.660
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.340 0.660
N44 Torsion of testis
0.000 0.340 0.660
E06 Thyroiditis
0.659 0.341 0.000
D59 Acquired haemolytic anaemia
0.659 0.341 0.000
E24.2 Drug-induced Cushing's syndrome
0.658 0.341 0.000
I77.8 Other specified disorders of arteries and arterioles
0.658 0.342 0.000
W00-W19 Falls
0.658 0.342 0.000
N46 Male infertility
0.000 0.342 0.658
H35.7 Separation of retinal layers
0.658 0.342 0.000
N45 Orchitis and epididymitis
0.000 0.343 0.657
N42.3 Dysplasia of prostate
0.000 0.343 0.657
M07.6 Other enteropathic arthropathies
0.656 0.344 0.000
M07.5 Arthropathy in ulcerative colitis
0.656 0.344 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.656 0.344 0.000
M07.2 Psoriatic spondylitis
0.656 0.344 0.000
M07.1 Arthritis mutilans
0.656 0.344 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.656 0.344 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.655 0.345 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.655 0.345 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.655 0.345 0.000
I78 Diseases of capillaries
0.655 0.345 0.000
L84 Corns and callosities
0.655 0.345 0.000
M22.1 Recurrent subluxation of patella
0.654 0.346 0.000
M22.9 Disorder of patella, unspecified
0.654 0.346 0.000
H43.2 Crystalline deposits in vitreous body
0.653 0.347 0.000
S93.3 Dislocation of other and unspecified parts of foot
0.650 0.350 0.000
L51 Erythema multiforme
0.650 0.350 0.000
E53 Deficiency of other B group vitamins
0.649 0.351 0.000
L43 Lichen planus
0.648 0.352 0.000
H43.0 Vitreous prolapse
0.647 0.353 0.000
I73.0 Raynaud's syndrome
0.647 0.353 0.000
Q35-Q37 Cleft lip and cleft palate
0.646 0.354 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.646 0.354 0.000
N32.1 Vesicointestinal fistula
0.000 0.355 0.645
M67.4 Ganglion
0.645 0.355 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.645 0.355 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.644 0.356 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.644 0.356 0.000
H05.2 Exophthalmic conditions
0.644 0.356 0.000
H47.2 Optic atrophy
0.642 0.358 0.000
M31.9 Necrotising vasculopathy, unspecified
0.641 0.359 0.000
M31.8 Other specified necrotising vasculopathies
0.641 0.359 0.000
M31.7 Microscopic polyangiitis
0.641 0.359 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.641 0.359 0.000
M31.2 Lethal midline granuloma
0.641 0.359 0.000
M31.1 Thrombotic microangiopathy
0.641 0.359 0.000
M31.0 Hypersensitivity angiitis
0.641 0.359 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.640 0.360 0.000
L12 Pemphigoid
0.640 0.360 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.639 0.361 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.639 0.361 0.000
E11.1 With ketoacidosis
0.638 0.362 0.000
S02.8 Fractures of other skull and facial bones
0.637 0.362 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.636 0.364 0.000
H02.0 Entropion and trichiasis of eyelid
0.636 0.364 0.000
L80 Vitiligo
0.635 0.365 0.000
N32.8 Other specified disorders of bladder
0.000 0.365 0.635
L28.1 Prurigo nodularis
0.634 0.366 0.000
Q45 Other congenital malformations of digestive system
0.634 0.366 0.000
E34 Other endocrine disorders
0.633 0.366 0.000
L21 Seborrhoeic dermatitis
0.633 0.367 0.000
H43.9 Disorder of vitreous body, unspecified
0.633 0.367 0.000
K50-K52 Noninfective enteritis and colitis
0.179 0.367 0.453
N42.2 Atrophy of prostate
0.000 0.368 0.632
I70 Atherosclerosis
0.632 0.368 0.000
H44 Disorders of globe
0.631 0.369 0.000
S21.1 Open wound of front wall of thorax
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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