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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17806562
log Bayes Factor = 12.277
Chromosome 22   position 17,450,247  (GRCh37) Explore rs17806562 on Ensembl!
Variant rs17806562 is part of Cluster X0072

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
M15-M19 Arthrosis
0.999 0.001 0.000
M19 Other arthrosis
0.998 0.002 0.000
J90-J94 Other diseases of pleura
0.998 0.002 0.000
M19.9 Arthrosis, unspecified
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
J90 Pleural effusion, not elsewhere classified
0.993 0.007 0.000
J09-J18 Influenza and pneumonia
0.988 0.012 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.987 0.013 0.000
Chapter V Mental and behavioural disorders
0.986 0.014 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.983 0.017 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.983 0.017 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.982 0.018 0.000
D60-D64 Aplastic and other anaemias
0.971 0.029 0.000
M50-M54 Other dorsopathies
0.963 0.037 0.000
D64 Other anaemias
0.962 0.038 0.000
M54 Dorsalgia
0.957 0.043 0.000
D64.9 Anaemia, unspecified
0.955 0.045 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.951 0.049 0.000
Chapter XI Diseases of the digestive system
0.947 0.053 0.000
M20-M25 Other joint disorders
0.946 0.054 0.000
M54.9 Dorsalgia, unspecified
0.944 0.056 0.000
Chapter XXII Codes for special purposes
0.944 0.056 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.944 0.056 0.000
M19.94 Arthrosis, unspecified (Hand)
0.934 0.066 0.000
J18 Pneumonia, organism unspecified
0.927 0.073 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.922 0.078 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.921 0.079 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.919 0.081 0.000
K70-K77 Diseases of liver
0.917 0.083 0.000
J20-J22 Other acute lower respiratory infections
0.910 0.089 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.910 0.090 0.000
M25 Other joint disorders, not elsewhere classified
0.909 0.091 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.903 0.097 0.000
S90-S99 Injuries to the ankle and foot
0.901 0.099 0.000
J18.1 Lobar pneumonia, unspecified
0.898 0.102 0.000
F10.2 Dependence syndrome
0.896 0.104 0.000
J00-J06 Acute upper respiratory infections
0.895 0.105 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.894 0.106 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.894 0.106 0.000
J91 Pleural effusion in conditions classified elsewhere
0.888 0.112 0.000
M18 Arthrosis of first carpometacarpal joint
0.887 0.113 0.000
M25.7 Osteophyte
0.884 0.116 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.880 0.120 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.877 0.123 0.000
O42 Premature rupture of membranes
0.875 0.125 0.000
M45-M49 Spondylopathies
0.875 0.125 0.000
M15 Polyarthrosis
0.875 0.125 0.000
M54.5 Low back pain
0.875 0.125 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.873 0.127 0.000
Y40 Systemic antibiotics
0.873 0.127 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.870 0.130 0.000
J94 Other pleural conditions
0.870 0.130 0.000
F10.0 Acute intoxication
0.868 0.132 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.867 0.133 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.867 0.133 0.000
M19.1 Posttraumatic arthrosis of other joints
0.867 0.133 0.000
M40-M43 Deforming dorsopathies
0.866 0.134 0.000
Chapter II Neoplasms
0.865 0.135 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.863 0.137 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.863 0.137 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.861 0.139 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.860 0.140 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.858 0.142 0.000
Chapter I Certain infectious and parasitic diseases
0.856 0.144 0.000
Chapter VI Diseases of the nervous system
0.855 0.145 0.000
J22 Unspecified acute lower respiratory infection
0.846 0.154 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.844 0.156 0.000
M24 Other specific joint derangements
0.842 0.158 0.000
C15-C26 Malignant neoplasms of digestive organs
0.837 0.163 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.833 0.167 0.000
M86-M90 Other osteopathies
0.833 0.167 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.831 0.169 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.829 0.171 0.000
M25.77 Osteophyte (Ankle and foot)
0.829 0.171 0.000
M05-M14 Inflammatory polyarthropathies
0.827 0.173 0.000
M54.59 Low back pain (Site unspecified)
0.823 0.177 0.000
K86 Other diseases of pancreas
0.823 0.177 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.819 0.181 0.000
S40-S49 Injuries to the shoulder and upper arm
0.814 0.186 0.000
K83 Other diseases of biliary tract
0.812 0.188 0.000
Y43 Primarily systemic agents
0.811 0.189 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.811 0.189 0.000
D70 Agranulocytosis
0.810 0.190 0.000
M19.98 Arthrosis, unspecified (Other)
0.809 0.191 0.000
J95-J99 Other diseases of the respiratory system
0.809 0.191 0.000
K76 Other diseases of liver
0.808 0.192 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.808 0.192 0.000
M22 Disorders of patella
0.807 0.193 0.000
Chapter VIII Diseases of the ear and mastoid process
0.805 0.195 0.000
M19.0 Primary arthrosis of other joints
0.802 0.198 0.000
F60-F69 Disorders of adult personality and behaviour
0.802 0.198 0.000
K81 Cholecystitis
0.800 0.200 0.000
M25.71 Osteophyte (Shoulder region)
0.799 0.201 0.000
Y42.7 Androgens and anabolic congeners
0.799 0.201 0.000
S50-S59 Injuries to the elbow and forearm
0.799 0.201 0.000
J80 Adult respiratory distress syndrome
0.799 0.201 0.000
S10-S19 Injuries to the neck
0.797 0.203 0.000
O60-O75 Complications of labour and delivery
0.796 0.204 0.000
C18 Malignant neoplasm of colon
0.794 0.206 0.000
O85-O92 Complications predominantly related to the puerperium
0.793 0.207 0.000
S60-S69 Injuries to the wrist and hand
0.790 0.210 0.000
C15 Malignant neoplasm of oesophagus
0.788 0.212 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.787 0.213 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.786 0.214 0.000
Y57 Other and unspecified drugs and medicaments
0.785 0.215 0.000
Chapter VII Diseases of the eye and adnexa
0.783 0.217 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.782 0.218 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.781 0.219 0.000
U80 Agent resistant to penicillin and related antibiotics
0.780 0.220 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.779 0.221 0.000
K73 Chronic hepatitis, not elsewhere classified
0.779 0.221 0.000
V20-V29 Motorcycle rider injured in transport accident
0.778 0.222 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.777 0.223 0.000
Y40.9 Systemic antibiotic, unspecified
0.775 0.225 0.000
X60-X84 Intentional self-harm
0.771 0.229 0.000
T79-T79 Certain early complications of trauma
0.771 0.229 0.000
V80-V89 Other land transport accidents
0.771 0.229 0.000
O47 False labour
0.770 0.230 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.770 0.230 0.000
M54.4 Lumbago with sciatica
0.768 0.232 0.000
M10 Gout
0.767 0.233 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.766 0.234 0.000
M48 Other spondylopathies
0.765 0.235 0.000
M34 Systemic sclerosis
0.765 0.235 0.000
S70-S79 Injuries to the hip and thigh
0.765 0.235 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.765 0.235 0.000
F99-F99 Unspecified mental disorder
0.764 0.235 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.763 0.236 0.000
S92 Fracture of foot, except ankle
0.762 0.238 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.761 0.239 0.000
M41 Scoliosis
0.760 0.240 0.000
T92 Sequelae of injuries of upper limb
0.757 0.243 0.000
K40-K46 Hernia
0.757 0.243 0.000
W00-W19 Falls
0.755 0.245 0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)
0.755 0.245 0.000
V40-V49 Car occupant injured in transport accident
0.753 0.247 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.752 0.248 0.000
J02 Acute pharyngitis
0.752 0.248 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.752 0.248 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.751 0.249 0.000
K80 Cholelithiasis
0.750 0.250 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.750 0.250 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.749 0.251 0.000
M45 Ankylosing spondylitis
0.747 0.253 0.000
O30 Multiple gestation
0.746 0.254 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.745 0.255 0.000
G90-G99 Other disorders of the nervous system
0.745 0.255 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.745 0.255 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.743 0.257 0.000
M00-M03 Infectious arthropathies
0.742 0.257 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.742 0.258 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.740 0.260 0.000
W50-W64 Exposure to animate mechanical forces
0.740 0.260 0.000
K65-K67 Diseases of peritoneum
0.739 0.261 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.737 0.262 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.737 0.263 0.000
J00 Acute nasopharyngitis [common cold]
0.737 0.263 0.000
S90 Superficial injury of ankle and foot
0.737 0.263 0.000
A30-A49 Other bacterial diseases
0.737 0.263 0.000
M25.4 Effusion of joint
0.736 0.264 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.736 0.264 0.000
F80-F89 Disorders of psychological development
0.734 0.266 0.000
K72 Hepatic failure, not elsewhere classified
0.734 0.266 0.000
M21 Other acquired deformities of limbs
0.733 0.267 0.000
J10 Influenza due to identified influenza virus
0.732 0.268 0.000
J94.8 Other specified pleural conditions
0.732 0.268 0.000
C71 Malignant neoplasm of brain
0.732 0.268 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.731 0.269 0.000
O44 Placenta praevia
0.730 0.270 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.730 0.270 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.729 0.271 0.000
K86.2 Cyst of pancreas
0.727 0.273 0.000
K75 Other inflammatory liver diseases
0.725 0.275 0.000
M10.9 Gout, unspecified
0.724 0.276 0.000
X50-X57 Overexertion, travel and privation
0.722 0.278 0.000
K55-K64 Other diseases of intestines
0.721 0.279 0.000
J01 Acute sinusitis
0.720 0.279 0.000
J18.0 Bronchopneumonia, unspecified
0.720 0.280 0.000
K63 Other diseases of intestine
0.720 0.280 0.000
C15.9 Oesophagus, unspecified
0.719 0.281 0.000
T66-T78 Other and unspecified effects of external causes
0.718 0.282 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.718 0.282 0.000
K70 Alcoholic liver disease
0.718 0.282 0.000
K63.5 Polyp of colon
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M19.8 Other specified arthrosis
0.715 0.284 0.000
M19.2 Other secondary arthrosis
0.715 0.284 0.000
D55-D59 Haemolytic anaemias
0.714 0.286 0.000
F11 Mental and behavioural disorders due to use of opioids
0.714 0.286 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.714 0.286 0.000
T90 Sequelae of injuries of head
0.714 0.286 0.000
J84 Other interstitial pulmonary diseases
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
J14 Pneumonia due to Haemophilus influenzae
0.713 0.287 0.000
M25.76 Osteophyte (Lower leg)
0.713 0.287 0.000
M24.5 Contracture of joint
0.712 0.288 0.000
X20-X29 Contact with venomous animals and plants
0.712 0.288 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.712 0.288 0.000
M15.1 Heberden's nodes (with arthropathy)
0.710 0.290 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.710 0.290 0.000
T98 Sequelae of other and unspecified effects of external causes
0.710 0.290 0.000
D50-D53 Nutritional anaemias
0.709 0.291 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.709 0.291 0.000
J17 Pneumonia in diseases classified elsewhere
0.708 0.291 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.708 0.291 0.000
J12 Viral pneumonia, not elsewhere classified
0.708 0.291 0.000
J11 Influenza, virus not identified
0.708 0.291 0.000
J09 Influenza due to certain identified influenza virus
0.708 0.291 0.000
D80-D89 Certain disorders involving the immune mechanism
0.708 0.292 0.000
M25.3 Other instability of joint
0.708 0.292 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.707 0.293 0.000
F70-F79 Mental retardation
0.707 0.293 0.000
M54.3 Sciatica
0.707 0.293 0.000
Q60-Q64 Congenital malformations of the urinary system
0.707 0.293 0.000
J94.2 Haemothorax
0.706 0.293 0.000
M86 Osteomyelitis
0.706 0.294 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.705 0.295 0.000
T33-T35 Frostbite
0.705 0.295 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.705 0.295 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.705 0.295 0.000
T00-T07 Injuries involving multiple body regions
0.705 0.295 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.704 0.296 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.704 0.296 0.000
Y59 Other and unspecified vaccines and biological substances
0.704 0.296 0.000
Y58 Bacterial vaccines
0.704 0.296 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.704 0.296 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.704 0.296 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.704 0.296 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.704 0.296 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.704 0.296 0.000
Y48 Anaesthetics and therapeutic gases
0.704 0.296 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.704 0.296 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.704 0.296 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.704 0.296 0.000
T91 Sequelae of injuries of neck and trunk
0.704 0.296 0.000
K83.1 Obstruction of bile duct
0.703 0.297 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.703 0.297 0.000
O80-O84 Delivery
0.701 0.298 0.000
M25.72 Osteophyte (Upper arm)
0.701 0.299 0.000
H43-H45 Disorders of vitreous body and globe
0.701 0.299 0.000
M10.99 Gout, unspecified (Site unspecified)
0.700 0.300 0.000
M53 Other dorsopathies, not elsewhere classified
0.700 0.300 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.700 0.300 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.699 0.301 0.000
M24.2 Disorder of ligament
0.698 0.302 0.000
M22.4 Chondromalacia patellae
0.698 0.302 0.000
U80.1 Methicillin resistant agent
0.697 0.303 0.000
M25.0 Haemarthrosis
0.696 0.304 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.696 0.304 0.000
C18.2 Ascending colon
0.696 0.304 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.695 0.305 0.000
C18.4 Transverse colon
0.695 0.305 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.695 0.305 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.695 0.305 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.694 0.306 0.000
G35 Multiple sclerosis
0.694 0.306 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.694 0.306 0.000
G40-G47 Episodic and paroxysmal disorders
0.693 0.307 0.000
U51 Admission status on psychiatric patients
0.693 0.307 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.692 0.308 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.692 0.308 0.000
C16 Malignant neoplasm of stomach
0.692 0.308 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.690 0.309 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.690 0.310 0.000
D64.8 Other specified anaemias
0.689 0.310 0.000
D64.4 Congenital dyserythropoietic anaemia
0.689 0.310 0.000
D64.3 Other sideroblastic anaemias
0.689 0.310 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.689 0.310 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.689 0.310 0.000
D64.0 Hereditary sideroblastic anaemia
0.689 0.310 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.688 0.312 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.688 0.312 0.000
J92 Pleural plaque
0.688 0.312 0.000
K81.0 Acute cholecystitis
0.688 0.312 0.000
M48.0 Spinal stenosis
0.687 0.313 0.000
M54.8 Other dorsalgia
0.686 0.314 0.000
M54.6 Pain in thoracic spine
0.686 0.314 0.000
M54.0 Panniculitis affecting regions of neck and back
0.686 0.314 0.000
M91-M94 Chondropathies
0.685 0.315 0.000
M65-M68 Disorders of synovium and tendon
0.685 0.315 0.000
F20 Schizophrenia
0.684 0.316 0.000
M41.9 Scoliosis, unspecified
0.683 0.317 0.000
J15.1 Pneumonia due to Pseudomonas
0.683 0.317 0.000
M22.3 Other derangements of patella
0.683 0.317 0.000
O45 Premature separation of placenta [abruptio placentae]
0.682 0.318 0.000
O43 Placental disorders
0.682 0.318 0.000
O41 Other disorders of amniotic fluid and membranes
0.682 0.318 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.682 0.318 0.000
O33 Maternal care for known or suspected disproportion
0.682 0.318 0.000
O31 Complications specific to multiple gestation
0.682 0.318 0.000
J03 Acute tonsillitis
0.682 0.318 0.000
K81.1 Chronic cholecystitis
0.682 0.318 0.000
G93 Other disorders of brain
0.680 0.320 0.000
K01 Embedded and impacted teeth
0.679 0.321 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.678 0.322 0.000
M33 Dermatopolymyositis
0.678 0.322 0.000
M32 Systemic lupus erythematosus
0.678 0.322 0.000
M30 Polyarteritis nodosa and related conditions
0.678 0.322 0.000
W20-W49 Exposure to inanimate mechanical forces
0.677 0.323 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.677 0.323 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.677 0.323 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.677 0.323 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.677 0.323 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.677 0.323 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.677 0.323 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.677 0.323 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.677 0.323 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.677 0.323 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.677 0.323 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.677 0.323 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.677 0.323 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.677 0.323 0.000
J60-J70 Lung diseases due to external agents
0.676 0.323 0.000
S91 Open wound of ankle and foot
0.675 0.325 0.000
K74 Fibrosis and cirrhosis of liver
0.674 0.326 0.000
U89 Agent resistant to other and unspecified antibiotics
0.673 0.327 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.672 0.328 0.000
Y43.4 Immunosuppressive agents
0.672 0.328 0.000
S60 Superficial injury of wrist and hand
0.671 0.329 0.000
K63.9 Disease of intestine, unspecified
0.671 0.329 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.671 0.329 0.000
B95-B98 Bacterial, viral and other infectious agents
0.671 0.329 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.670 0.329 0.000
F60 Specific personality disorders
0.670 0.330 0.000
G40 Epilepsy
0.669 0.331 0.000
M05 Seropositive rheumatoid arthritis
0.668 0.332 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.667 0.332 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.667 0.333 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.666 0.333 0.000
K10 Other diseases of jaws
0.666 0.334 0.000
G37 Other demyelinating diseases of central nervous system
0.666 0.334 0.000
H55-H59 Other disorders of eye and adnexa
0.666 0.334 0.000
F29 Unspecified nonorganic psychosis
0.665 0.335 0.000
J18.8 Other pneumonia, organism unspecified
0.665 0.335 0.000
J18.2 Hypostatic pneumonia, unspecified
0.665 0.335 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.663 0.337 0.000
B15-B19 Viral hepatitis
0.663 0.337 0.000
F30-F39 Mood [affective] disorders
0.662 0.338 0.000
K86.1 Other chronic pancreatitis
0.662 0.338 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.661 0.339 0.000
F10.9 Unspecified mental and behavioural disorder
0.661 0.339 0.000
F10.8 Other mental and behavioural disorders
0.661 0.339 0.000
F10.7 Residual and late-onset psychotic disorder
0.661 0.339 0.000
F10.6 Amnesic syndrome
0.661 0.339 0.000
F10.5 Psychotic disorder
0.661 0.339 0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)
0.660 0.340 0.000
C15.4 Middle third of oesophagus
0.659 0.341 0.000
C18.5 Splenic flexure
0.659 0.341 0.000
C91 Lymphoid leukaemia
0.658 0.342 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.658 0.342 0.000
S40 Superficial injury of shoulder and upper arm
0.658 0.342 0.000
K77 Liver disorders in diseases classified elsewhere
0.657 0.342 0.000
K71 Toxic liver disease
0.657 0.342 0.000
S41 Open wound of shoulder and upper arm
0.656 0.344 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.656 0.344 0.000
C71.1 Frontal lobe
0.656 0.344 0.000
M54.50 Low back pain (Multiple sites in spine)
0.656 0.344 0.000
Y44 Agents primarily affecting blood constituents
0.655 0.344 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.655 0.345 0.000
J20 Acute bronchitis
0.655 0.345 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.654 0.346 0.000
O40 Polyhydramnios
0.653 0.346 0.000
J21 Acute bronchiolitis
0.653 0.347 0.000
H21 Other disorders of iris and ciliary body
0.653 0.347 0.000
H60-H62 Diseases of external ear
0.653 0.347 0.000
U88 Agent resistant to multiple antibiotics
0.652 0.348 0.000
M25.9 Joint disorder, unspecified
0.652 0.348 0.000
M25.2 Flail joint
0.652 0.348 0.000
M25.1 Fistula of joint
0.652 0.348 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.652 0.348 0.000
C18.3 Hepatic flexure
0.651 0.349 0.000
K43 Ventral hernia
0.651 0.349 0.000
K08 Other disorders of teeth and supporting structures
0.651 0.349 0.000
Y57.5 X-ray contrast media
0.650 0.349 0.000
O86 Other puerperal infections
0.650 0.350 0.000
F10.3 Withdrawal state
0.650 0.350 0.000
O20 Haemorrhage in early pregnancy
0.650 0.350 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.650 0.350 0.000
S80-S89 Injuries to the knee and lower leg
0.649 0.351 0.000
K41 Femoral hernia
0.649 0.351 0.000
J02.9 Acute pharyngitis, unspecified
0.649 0.351 0.000
D61 Other aplastic anaemias
0.648 0.352 0.000
D73 Diseases of spleen
0.647 0.353 0.000
O21 Excessive vomiting in pregnancy
0.647 0.353 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.647 0.353 0.000
J15.4 Pneumonia due to other streptococci
0.646 0.354 0.000
H90-H95 Other disorders of ear
0.646 0.354 0.000
S99 Other and unspecified injuries of ankle and foot
0.646 0.354 0.000
S98 Traumatic amputation of ankle and foot
0.646 0.354 0.000
S97 Crushing injury of ankle and foot
0.646 0.354 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.646 0.354 0.000
S95 Injury of blood vessels at ankle and foot level
0.646 0.354 0.000
S94 Injury of nerves at ankle and foot level
0.646 0.354 0.000
M43 Other deforming dorsopathies
0.646 0.354 0.000
J15.2 Pneumonia due to staphylococcus
0.645 0.355 0.000
Q80-Q89 Other congenital malformations
0.645 0.355 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.645 0.355 0.000
O00-O08 Pregnancy with abortive outcome
0.644 0.356 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.644 0.356 0.000
J98 Other respiratory disorders
0.643 0.356 0.000
S52 Fracture of forearm
0.643 0.357 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.642 0.358 0.000
F01 Vascular dementia
0.642 0.358 0.000
M25.47 Effusion of joint (Ankle and foot)
0.642 0.358 0.000
T95 Sequelae of burns, corrosions and frostbite
0.641 0.359 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.641 0.359 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.641 0.359 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.641 0.359 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.641 0.359 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.640 0.360 0.000
K83.0 Cholangitis
0.640 0.360 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.639 0.361 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.638 0.362 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.637 0.363 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.637 0.363 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.636 0.364 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.636 0.364 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.636 0.364 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.636 0.364 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.636 0.364 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.636 0.364 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.636 0.364 0.000
J04 Acute laryngitis and tracheitis
0.636 0.364 0.000
M34.8 Other forms of systemic sclerosis
0.634 0.365 0.000
O23 Infections of genito-urinary tract in pregnancy
0.634 0.366 0.000
M25.79 Osteophyte (Site unspecified)
0.634 0.366 0.000
M25.73 Osteophyte (Forearm)
0.634 0.366 0.000
M25.70 Osteophyte (Multiple sites)
0.634 0.366 0.000
Y52 Agents primarily affecting the cardiovascular system
0.633 0.367 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.633 0.367 0.000
K73.9 Chronic hepatitis, unspecified
0.632 0.368 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.631 0.369 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.631 0.369 0.000
T42.4 Benzodiazepines
0.630 0.370 0.000
M54.1 Radiculopathy
0.630 0.370 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.630 0.370 0.000
F10.4 Withdrawal state with delirium
0.630 0.370 0.000
S68 Traumatic amputation of wrist and hand
0.630 0.370 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.628 0.372 0.000
H18 Other disorders of cornea
0.628 0.372 0.000
H43 Disorders of vitreous body
0.628 0.372 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.628 0.372 0.000
M49 Spondylopathies in diseases classified elsewhere
0.627 0.372 0.000
D62 Acute posthaemorrhagic anaemia
0.627 0.372 0.000
M15.9 Polyarthrosis, unspecified
0.627 0.373 0.000
M15.0 Primary generalised (osteo)arthrosis
0.627 0.373 0.000
M15.8 Other polyarthrosis
0.627 0.373 0.000
M15.4 Erosive (osteo)arthrosis
0.627 0.373 0.000
M15.3 Secondary multiple arthrosis
0.627 0.373 0.000
K85 Acute pancreatitis
0.627 0.373 0.000
M54.55 Low back pain (Thoracolumbar region)
0.627 0.373 0.000
M54.54 Low back pain-Thoracic
0.627 0.373 0.000
M54.53 Low back pain-Cervicothoracic
0.627 0.373 0.000
M54.52 Low back pain-Cervical
0.627 0.373 0.000
M54.51 Low back pain-Occipit-atl-axl
0.627 0.373 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.626 0.374 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.626 0.374 0.000
O34.6 Maternal care for abnormality of vagina
0.626 0.374 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.626 0.374 0.000
O34.4 Maternal care for other abnormalities of cervix
0.626 0.374 0.000
O34.3 Maternal care for cervical incompetence
0.626 0.374 0.000
O34.0 Maternal care for congenital malformation of uterus
0.626 0.374 0.000
Y40.7 Antifungal antibiotics, systemically used
0.626 0.374 0.000
Y40.6 Rifamycins
0.626 0.374 0.000
Y40.5 Aminoglycosides
0.626 0.374 0.000
Y40.4 Tetracyclines
0.626 0.374 0.000
Y40.3 Macrolides
0.626 0.374 0.000
Y40.2 Chloramphenicol group
0.626 0.374 0.000
M54.57 Low back pain (Lumbosacral region)
0.625 0.375 0.000
U80.0 Penicillin resistant agent
0.625 0.375 0.000
A80-A89 Viral infections of the central nervous system
0.625 0.375 0.000
S92.0 Fracture of calcaneus
0.624 0.376 0.000
M48.06 Spinal stenosis (Lumbar region)
0.624 0.376 0.000
G40.9 Epilepsy, unspecified
0.624 0.376 0.000
H20 Iridocyclitis
0.624 0.376 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.624 0.376 0.000
Q35-Q37 Cleft lip and cleft palate
0.624 0.376 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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