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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17819946
log Bayes Factor = 15.2912
Chromosome 15   position 57,428,671  (GRCh37) Explore rs17819946 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I20 Angina pectoris
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
I20.9 Angina pectoris, unspecified
0.997 0.003 0.000
I30-I52 Other forms of heart disease
0.994 0.006 0.000
J40-J47 Chronic lower respiratory diseases
0.994 0.006 0.000
M20-M25 Other joint disorders
0.994 0.006 0.000
J44 Other chronic obstructive pulmonary disease
0.993 0.007 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.993 0.007 0.000
Chapter V Mental and behavioural disorders
0.991 0.009 0.000
Chapter VII Diseases of the eye and adnexa
0.988 0.012 0.000
Chapter VI Diseases of the nervous system
0.988 0.012 0.000
E10-E14 Diabetes mellitus
0.986 0.014 0.000
E11 Non-insulin-dependent diabetes mellitus
0.984 0.016 0.000
E11.9 Without complications
0.984 0.016 0.000
M45-M49 Spondylopathies
0.973 0.027 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.972 0.028 0.000
I60-I69 Cerebrovascular diseases
0.966 0.034 0.000
I25 Chronic ischaemic heart disease
0.964 0.036 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.961 0.039 0.000
M50-M54 Other dorsopathies
0.958 0.042 0.000
H43-H45 Disorders of vitreous body and globe
0.958 0.042 0.000
I20.0 Unstable angina
0.956 0.044 0.000
I50 Heart failure
0.952 0.048 0.000
R79 Other abnormal findings of blood chemistry
0.950 0.050 0.000
M23 Internal derangement of knee
0.946 0.054 0.000
I42 Cardiomyopathy
0.946 0.054 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.939 0.061 0.000
H43 Disorders of vitreous body
0.939 0.061 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.938 0.062 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.937 0.063 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.930 0.070 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.930 0.070 0.000
M54 Dorsalgia
0.927 0.073 0.000
M25 Other joint disorders, not elsewhere classified
0.916 0.084 0.000
M47 Spondylosis
0.914 0.086 0.000
I25.2 Old myocardial infarction
0.908 0.092 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.908 0.092 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.908 0.092 0.000
M40-M43 Deforming dorsopathies
0.908 0.092 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.905 0.095 0.000
M46 Other inflammatory spondylopathies
0.902 0.098 0.000
I47 Paroxysmal tachycardia
0.902 0.098 0.000
I63 Cerebral infarction
0.901 0.099 0.000
H43.8 Other disorders of vitreous body
0.898 0.102 0.000
M22 Disorders of patella
0.896 0.104 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.893 0.107 0.000
R30-R39 Symptoms and signs involving the urinary system
0.890 0.110 0.000
M70-M79 Other soft tissue disorders
0.884 0.116 0.000
Chapter XI Diseases of the digestive system
0.882 0.118 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.880 0.120 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.880 0.120 0.000
M54.5 Low back pain
0.879 0.121 0.000
J47 Bronchiectasis
0.876 0.124 0.000
I50.0 Congestive heart failure
0.875 0.125 0.000
I42.9 Cardiomyopathy, unspecified
0.873 0.127 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.870 0.130 0.000
M23.3 Other meniscus derangements
0.868 0.132 0.000
I47.1 Supraventricular tachycardia
0.862 0.138 0.000
E70-E90 Metabolic disorders
0.860 0.140 0.000
R35 Polyuria
0.857 0.143 0.000
H52 Disorders of refraction and accommodation
0.854 0.146 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.852 0.148 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.852 0.148 0.000
I63.9 Cerebral infarction, unspecified
0.846 0.154 0.000
F30-F39 Mood [affective] disorders
0.843 0.157 0.000
G20-G26 Extrapyramidal and movement disorders
0.843 0.157 0.000
M54.59 Low back pain (Site unspecified)
0.842 0.158 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.842 0.158 0.000
I44 Atrioventricular and left bundle-branch block
0.841 0.159 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.830 0.170 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.829 0.171 0.000
I21 Acute myocardial infarction
0.829 0.171 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.828 0.172 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.826 0.174 0.000
M22.4 Chondromalacia patellae
0.823 0.177 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.823 0.177 0.000
I67 Other cerebrovascular diseases
0.822 0.178 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.821 0.179 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.820 0.180 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.817 0.183 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.815 0.185 0.000
H43.1 Vitreous haemorrhage
0.814 0.186 0.000
M47.2 Other spondylosis with radiculopathy
0.813 0.187 0.000
I35 Nonrheumatic aortic valve disorders
0.810 0.190 0.000
H52.1 Myopia
0.810 0.190 0.000
I42.0 Dilated cardiomyopathy
0.808 0.192 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.808 0.192 0.000
M54.4 Lumbago with sciatica
0.807 0.193 0.000
K90-K93 Other diseases of the digestive system
0.806 0.194 0.000
F20 Schizophrenia
0.805 0.195 0.000
M41 Scoliosis
0.805 0.195 0.000
R73 Elevated blood glucose level
0.804 0.196 0.000
M15-M19 Arthrosis
0.802 0.198 0.000
H30-H36 Disorders of choroid and retina
0.801 0.199 0.000
I33 Acute and subacute endocarditis
0.801 0.199 0.000
G30-G32 Other degenerative diseases of the nervous system
0.798 0.202 0.000
I24 Other acute ischaemic heart diseases
0.798 0.202 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.797 0.203 0.000
R30 Pain associated with micturition
0.795 0.205 0.000
G40-G47 Episodic and paroxysmal disorders
0.792 0.207 0.000
M25.7 Osteophyte
0.790 0.210 0.000
M65-M68 Disorders of synovium and tendon
0.788 0.211 0.000
I45 Other conduction disorders
0.787 0.213 0.000
I50.9 Heart failure, unspecified
0.783 0.217 0.000
M54.9 Dorsalgia, unspecified
0.783 0.217 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.783 0.217 0.000
J90-J94 Other diseases of pleura
0.781 0.219 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.780 0.220 0.000
I50.1 Left ventricular failure
0.780 0.220 0.000
E65-E68 Obesity and other hyperalimentation
0.778 0.222 0.000
K70-K77 Diseases of liver
0.777 0.223 0.000
G70-G73 Diseases of myoneural junction and muscle
0.777 0.223 0.000
K92 Other diseases of digestive system
0.775 0.225 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.774 0.226 0.000
Chapter XXII Codes for special purposes
0.774 0.226 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.774 0.226 0.000
R94 Abnormal results of function studies
0.772 0.228 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.772 0.228 0.000
J00-J06 Acute upper respiratory infections
0.768 0.232 0.000
M80-M85 Disorders of bone density and structure
0.767 0.233 0.000
M20 Acquired deformities of fingers and toes
0.767 0.233 0.000
M47.9 Spondylosis, unspecified
0.766 0.234 0.000
F99-F99 Unspecified mental disorder
0.766 0.234 0.000
J45 Asthma
0.766 0.234 0.000
J30-J39 Other diseases of upper respiratory tract
0.764 0.236 0.000
M79.8 Other specified soft tissue disorders
0.763 0.237 0.000
Chapter XX External causes of morbidity and mortality
0.763 0.237 0.000
M50 Cervical disk disorders
0.762 0.238 0.000
F25 Schizoaffective disorders
0.761 0.239 0.000
E20-E35 Disorders of other endocrine glands
0.761 0.239 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.761 0.239 0.000
M19 Other arthrosis
0.760 0.240 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.759 0.241 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.759 0.241 0.000
F03 Unspecified dementia
0.758 0.242 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.757 0.243 0.000
M05-M14 Inflammatory polyarthropathies
0.756 0.244 0.000
M25.5 Pain in joint
0.756 0.244 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.756 0.244 0.000
I25.5 Ischaemic cardiomyopathy
0.754 0.246 0.000
M24 Other specific joint derangements
0.753 0.247 0.000
F43 Reaction to severe stress, and adjustment disorders
0.751 0.249 0.000
I84 Haemorrhoids
0.750 0.250 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.750 0.250 0.000
H43.3 Other vitreous opacities
0.749 0.251 0.000
M21 Other acquired deformities of limbs
0.744 0.256 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.742 0.258 0.000
M43 Other deforming dorsopathies
0.742 0.258 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.742 0.258 0.000
R39 Other symptoms and signs involving the urinary system
0.741 0.259 0.000
I87 Other disorders of veins
0.740 0.260 0.000
J84 Other interstitial pulmonary diseases
0.740 0.260 0.000
M34 Systemic sclerosis
0.736 0.264 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.736 0.264 0.000
F23 Acute and transient psychotic disorders
0.736 0.264 0.000
R79.0 Abnormal level of blood mineral
0.736 0.264 0.000
R94.5 Abnormal results of liver function studies
0.736 0.264 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.734 0.266 0.000
M41.9 Scoliosis, unspecified
0.732 0.268 0.000
G20 Parkinson's disease
0.732 0.268 0.000
F60-F69 Disorders of adult personality and behaviour
0.729 0.271 0.000
E50-E64 Other nutritional deficiencies
0.729 0.271 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.729 0.271 0.000
F80-F89 Disorders of psychological development
0.725 0.274 0.000
M86-M90 Other osteopathies
0.724 0.276 0.000
M47.8 Other spondylosis
0.723 0.277 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.722 0.278 0.000
E11.2 With renal complications
0.722 0.278 0.000
F20.9 Schizophrenia, unspecified
0.722 0.278 0.000
I62 Other nontraumatic intracranial haemorrhage
0.721 0.278 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.722 0.278 0.000
M91-M94 Chondropathies
0.720 0.280 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.720 0.280 0.000
I82 Other venous embolism and thrombosis
0.720 0.280 0.000
E87.5 Hyperkalaemia
0.719 0.281 0.000
J60-J70 Lung diseases due to external agents
0.718 0.282 0.000
I60 Subarachnoid haemorrhage
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I21.4 Acute subendocardial myocardial infarction
0.717 0.283 0.000
I05-I09 Chronic rheumatic heart diseases
0.716 0.284 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.715 0.285 0.000
H18 Other disorders of cornea
0.715 0.285 0.000
E14 Unspecified diabetes mellitus
0.715 0.285 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.714 0.286 0.000
H10-H13 Disorders of conjunctiva
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.713 0.287 0.000
I48 Atrial fibrillation and flutter
0.713 0.287 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.713 0.287 0.000
I41 Myocarditis in diseases classified elsewhere
0.713 0.287 0.000
I40 Acute myocarditis
0.713 0.287 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.713 0.287 0.000
I37 Pulmonary valve disorders
0.713 0.287 0.000
I36 Nonrheumatic tricuspid valve disorders
0.713 0.287 0.000
I32 Pericarditis in diseases classified elsewhere
0.713 0.287 0.000
I30 Acute pericarditis
0.713 0.287 0.000
G43 Migraine
0.713 0.287 0.000
J41 Simple and mucopurulent chronic bronchitis
0.713 0.287 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.287 0.000
M33 Dermatopolymyositis
0.713 0.287 0.000
M32 Systemic lupus erythematosus
0.713 0.287 0.000
M30 Polyarteritis nodosa and related conditions
0.713 0.287 0.000
E40-E46 Malnutrition
0.712 0.288 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.710 0.289 0.000
F70-F79 Mental retardation
0.710 0.289 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.710 0.289 0.000
R73.9 Hyperglycaemia, unspecified
0.710 0.290 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.710 0.290 0.000
M19.9 Arthrosis, unspecified
0.709 0.291 0.000
H55-H59 Other disorders of eye and adnexa
0.709 0.291 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.708 0.292 0.000
M54.6 Pain in thoracic spine
0.708 0.292 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.708 0.292 0.000
E13 Other specified diabetes mellitus
0.707 0.293 0.000
E12 Malnutrition-related diabetes mellitus
0.707 0.293 0.000
E11.8 With unspecified complications
0.705 0.294 0.000
E11.7 With multiple complications
0.705 0.294 0.000
E11.6 With other specified complications
0.705 0.294 0.000
E11.1 With ketoacidosis
0.705 0.294 0.000
E11.0 With coma
0.705 0.294 0.000
I35.0 Aortic (valve) stenosis
0.705 0.295 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.705 0.295 0.000
J80 Adult respiratory distress syndrome
0.704 0.295 0.000
K83 Other diseases of biliary tract
0.704 0.295 0.000
F29 Unspecified nonorganic psychosis
0.704 0.296 0.000
M45 Ankylosing spondylitis
0.703 0.297 0.000
F22 Persistent delusional disorders
0.703 0.297 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.703 0.297 0.000
I42.2 Other hypertrophic cardiomyopathy
0.702 0.298 0.000
M23.8 Other internal derangements of knee
0.702 0.298 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.702 0.298 0.000
I21.9 Acute myocardial infarction, unspecified
0.698 0.302 0.000
M49 Spondylopathies in diseases classified elsewhere
0.697 0.302 0.000
M79.1 Myalgia
0.697 0.303 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.697 0.303 0.000
M25.8 Other specified joint disorders
0.696 0.304 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.695 0.305 0.000
I67.8 Other specified cerebrovascular diseases
0.694 0.305 0.000
R76 Other abnormal immunological findings in serum
0.694 0.306 0.000
F05.9 Delirium, unspecified
0.693 0.307 0.000
I20.1 Angina pectoris with documented spasm
0.693 0.307 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.693 0.307 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.693 0.307 0.000
R30.0 Dysuria
0.693 0.307 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.692 0.308 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.692 0.308 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.692 0.308 0.000
I77 Other disorders of arteries and arterioles
0.692 0.308 0.000
I25.6 Silent myocardial ischaemia
0.691 0.309 0.000
I25.4 Coronary artery aneurysm
0.691 0.309 0.000
I25.3 Aneurysm of heart
0.691 0.309 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.691 0.309 0.000
I34 Nonrheumatic mitral valve disorders
0.689 0.311 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.689 0.311 0.000
R77 Other abnormalities of plasma proteins
0.689 0.311 0.000
R74 Abnormal serum enzyme levels
0.689 0.311 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.689 0.311 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.689 0.311 0.000
R71 Abnormality of red blood cells
0.689 0.311 0.000
I31 Other diseases of pericardium
0.688 0.312 0.000
M53 Other dorsopathies, not elsewhere classified
0.687 0.313 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.686 0.313 0.000
F31 Bipolar affective disorder
0.687 0.313 0.000
M31 Other necrotising vasculopathies
0.685 0.315 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.684 0.316 0.000
I61 Intracerebral haemorrhage
0.684 0.316 0.000
M25.4 Effusion of joint
0.683 0.317 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.683 0.317 0.000
I86 Varicose veins of other sites
0.682 0.318 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.681 0.319 0.000
I80 Phlebitis and thrombophlebitis
0.679 0.321 0.000
M23.9 Internal derangement of knee, unspecified
0.679 0.321 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.679 0.321 0.000
M23.5 Chronic instability of knee
0.679 0.321 0.000
M23.4 Loose body in knee
0.679 0.321 0.000
M23.1 Discoid meniscus (congenital)
0.679 0.321 0.000
M23.0 Cystic meniscus
0.679 0.321 0.000
I42.8 Other cardiomyopathies
0.678 0.322 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.678 0.322 0.000
I42.6 Alcoholic cardiomyopathy
0.678 0.322 0.000
I42.5 Other restrictive cardiomyopathy
0.678 0.322 0.000
I42.4 Endocardial fibroelastosis
0.678 0.322 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.678 0.322 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.678 0.322 0.000
J95-J99 Other diseases of the respiratory system
0.678 0.322 0.000
R45 Symptoms and signs involving emotional state
0.678 0.322 0.000
I44.0 Atrioventricular block, first degree
0.678 0.322 0.000
H02 Other disorders of eyelid
0.677 0.323 0.000
Chapter VIII Diseases of the ear and mastoid process
0.677 0.323 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.675 0.325 0.000
I22 Subsequent myocardial infarction
0.674 0.326 0.000
G90-G99 Other disorders of the nervous system
0.674 0.326 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.674 0.326 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.674 0.326 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.674 0.326 0.000
M22.2 Patellofemoral disorders
0.674 0.326 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.673 0.327 0.000
H43.9 Disorder of vitreous body, unspecified
0.673 0.327 0.000
H43.2 Crystalline deposits in vitreous body
0.673 0.327 0.000
H43.0 Vitreous prolapse
0.673 0.327 0.000
G54 Nerve root and plexus disorders
0.673 0.327 0.000
J42 Unspecified chronic bronchitis
0.673 0.327 0.000
K81 Cholecystitis
0.672 0.328 0.000
D50-D53 Nutritional anaemias
0.672 0.328 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.671 0.329 0.000
J35 Chronic diseases of tonsils and adenoids
0.671 0.329 0.000
I67.2 Cerebral atherosclerosis
0.670 0.330 0.000
R47-R49 Symptoms and signs involving speech and voice
0.670 0.330 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.669 0.330 0.000
M25.76 Osteophyte (Lower leg)
0.667 0.333 0.000
F28 Other nonorganic psychotic disorders
0.667 0.333 0.000
F24 Induced delusional disorder
0.667 0.333 0.000
F21 Schizotypal disorder
0.667 0.333 0.000
M65 Synovitis and tenosynovitis
0.666 0.334 0.000
M54.8 Other dorsalgia
0.665 0.335 0.000
M54.0 Panniculitis affecting regions of neck and back
0.665 0.335 0.000
I44.6 Other and unspecified fascicular block
0.663 0.337 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.663 0.337 0.000
I33.0 Acute and subacute infective endocarditis
0.663 0.337 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.663 0.337 0.000
G50 Disorders of trigeminal nerve
0.660 0.340 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.660 0.340 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.660 0.340 0.000
K76 Other diseases of liver
0.659 0.341 0.000
J92 Pleural plaque
0.659 0.341 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.659 0.341 0.000
D60-D64 Aplastic and other anaemias
0.658 0.342 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.658 0.342 0.000
M84 Disorders of continuity of bone
0.658 0.342 0.000
M25.9 Joint disorder, unspecified
0.657 0.343 0.000
M25.3 Other instability of joint
0.657 0.343 0.000
M25.2 Flail joint
0.657 0.343 0.000
M25.1 Fistula of joint
0.657 0.343 0.000
M25.0 Haemarthrosis
0.657 0.343 0.000
M71 Other bursopathies
0.656 0.344 0.000
F33 Recurrent depressive disorder
0.655 0.344 0.000
H04 Disorders of lachrymal system
0.655 0.345 0.000
M47.1 Other spondylosis with myelopathy
0.655 0.345 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.655 0.345 0.000
E11.3 With ophthalmic complications
0.654 0.346 0.000
E87.0 Hyperosmolality and hypernatraemia
0.653 0.347 0.000
E78.5 Hyperlipidaemia, unspecified
0.653 0.347 0.000
I84.8 Unspecified haemorrhoids with other complications
0.653 0.347 0.000
H51 Other disorders of binocular movement
0.651 0.349 0.000
H49 Paralytic strabismus
0.651 0.349 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.651 0.349 0.000
F02 Dementia in other diseases classified elsewhere
0.651 0.349 0.000
F09 Unspecified organic or symptomatic mental disorder
0.651 0.349 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.651 0.349 0.000
E11.5 With peripheral circulatory complications
0.651 0.349 0.000
M42 Spinal osteochondrosis
0.651 0.349 0.000
M40 Kyphosis and lordosis
0.651 0.349 0.000
M25.57 Pain in joint (Ankle and foot)
0.650 0.350 0.000
F00 Dementia in Alzheimer's disease
0.650 0.350 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.649 0.351 0.000
G58 Other mononeuropathies
0.649 0.351 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.649 0.351 0.000
G52 Disorders of other cranial nerves
0.649 0.351 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.648 0.352 0.000
I67.9 Cerebrovascular disease, unspecified
0.648 0.352 0.000
M46.8 Other specified inflammatory spondylopathies
0.647 0.353 0.000
M46.5 Other infective spondylopathies
0.647 0.353 0.000
M46.4 Discitis, unspecified
0.647 0.353 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.647 0.353 0.000
M46.2 Osteomyelitis of vertebra
0.647 0.353 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.647 0.353 0.000
M46.0 Spinal enthesopathy
0.647 0.353 0.000
I85 Oesophageal varices
0.647 0.353 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.647 0.353 0.000
I47.0 Reentry ventricular arrhythmia
0.647 0.353 0.000
I63.8 Other cerebral infarction
0.646 0.354 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.646 0.354 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.646 0.354 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.646 0.354 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.646 0.354 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.646 0.354 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.646 0.354 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.646 0.354 0.000
R30.9 Painful micturition, unspecified
0.644 0.355 0.000
J93 Pneumothorax
0.644 0.356 0.000
H44 Disorders of globe
0.643 0.356 0.000
K92.0 Haematemesis
0.643 0.357 0.000
F01 Vascular dementia
0.643 0.357 0.000
M22.1 Recurrent subluxation of patella
0.642 0.358 0.000
M22.9 Disorder of patella, unspecified
0.642 0.358 0.000
M22.3 Other derangements of patella
0.642 0.358 0.000
M22.0 Recurrent dislocation of patella
0.642 0.358 0.000
M77 Other enthesopathies
0.642 0.358 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.642 0.358 0.000
I78 Diseases of capillaries
0.642 0.358 0.000
J32 Chronic sinusitis
0.641 0.359 0.000
E11.4 With neurological complications
0.640 0.359 0.000
F25.9 Schizoaffective disorder, unspecified
0.640 0.359 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.640 0.360 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.640 0.360 0.000
H33 Retinal detachments and breaks
0.640 0.360 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.640 0.360 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.640 0.360 0.000
I71 Aortic aneurysm and dissection
0.639 0.361 0.000
F32 Depressive episode
0.639 0.361 0.000
E88 Other metabolic disorders
0.639 0.361 0.000
R36 Urethral discharge
0.638 0.362 0.000
R34 Anuria and oliguria
0.638 0.362 0.000
H50 Other strabismus
0.635 0.364 0.000
G37 Other demyelinating diseases of central nervous system
0.635 0.365 0.000
I81 Portal vein thrombosis
0.635 0.365 0.000
I45.6 Preexcitation syndrome
0.635 0.365 0.000
I38 Endocarditis, valve unspecified
0.634 0.365 0.000
M76 Enthesopathies of lower limb, excluding foot
0.634 0.366 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.634 0.366 0.000
M54.56 Low back pain (Lumbar region)
0.634 0.366 0.000
H52.2 Astigmatism
0.634 0.366 0.000
M19.0 Primary arthrosis of other joints
0.633 0.367 0.000
H31 Other disorders of choroid
0.633 0.367 0.000
I24.8 Other forms of acute ischaemic heart disease
0.632 0.368 0.000
I74 Arterial embolism and thrombosis
0.632 0.368 0.000
I88 Nonspecific lymphadenitis
0.631 0.369 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.631 0.369 0.000
I84.1 Internal haemorrhoids with other complications
0.631 0.369 0.000
I44.7 Left bundle-branch block, unspecified
0.630 0.370 0.000
M54.55 Low back pain (Thoracolumbar region)
0.630 0.370 0.000
M54.54 Low back pain-Thoracic
0.630 0.370 0.000
M54.53 Low back pain-Cervicothoracic
0.630 0.370 0.000
M54.52 Low back pain-Cervical
0.630 0.370 0.000
M54.51 Low back pain-Occipit-atl-axl
0.630 0.370 0.000
M54.50 Low back pain (Multiple sites in spine)
0.630 0.370 0.000
G40 Epilepsy
0.630 0.370 0.000
I10-I15 Hypertensive diseases
0.629 0.371 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.629 0.371 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.628 0.372 0.000
G43.9 Migraine, unspecified
0.627 0.372 0.000
W00-W19 Falls
0.627 0.373 0.000
M25.77 Osteophyte (Ankle and foot)
0.627 0.373 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.627 0.373 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.627 0.373 0.000
M20.4 Other hammer toe(s) (acquired)
0.627 0.373 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.626 0.374 0.000
E66 Obesity
0.624 0.376 0.000
J45.0 Predominantly allergic asthma
0.624 0.376 0.000
M43.1 Spondylolisthesis
0.623 0.377 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.622 0.378 0.000
M23.37 Other meniscus derangements-Capsular lig
0.622 0.378 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.622 0.378 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.622 0.378 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.622 0.378 0.000
M20.5 Other deformities of toe(s) (acquired)
0.620 0.380 0.000
I84.9 Unspecified haemorrhoids without complication
0.620 0.380 0.000
G25 Other extrapyramidal and movement disorders
0.620 0.380 0.000
H52.3 Anisometropia and aniseikonia
0.619 0.381 0.000
I72 Other aneurysm
0.618 0.381 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.618 0.382 0.000
M50.3 Other cervical disk degeneration
0.617 0.383 0.000
F43.0 Acute stress reaction
0.617 0.383 0.000
E85 Amyloidosis
0.616 0.384 0.000
E84 Cystic fibrosis
0.616 0.384 0.000
E79 Disorders of purine and pyrimidine metabolism
0.616 0.384 0.000
E77 Disorders of glycoprotein metabolism
0.616 0.384 0.000
E76 Disorders of glycosaminoglycan metabolism
0.616 0.384 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.616 0.384 0.000
E74 Other disorders of carbohydrate metabolism
0.616 0.384 0.000
E73 Lactose intolerance
0.616 0.384 0.000
E72 Other disorders of amino-acid metabolism
0.616 0.384 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.616 0.384 0.000
E70 Disorders of aromatic amino-acid metabolism
0.616 0.384 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.616 0.384 0.000
R21 Rash and other nonspecific skin eruption
0.616 0.384 0.000
I44.2 Atrioventricular block, complete
0.615 0.385 0.000
F43.2 Adjustment disorders
0.615 0.385 0.000
M22.8 Other disorders of patella
0.615 0.385 0.000
G72 Other myopathies
0.614 0.386 0.000
K92.9 Disease of digestive system, unspecified
0.614 0.386 0.000
M48 Other spondylopathies
0.613 0.387 0.000
F43.1 Posttraumatic stress disorder
0.613 0.387 0.000
H52.7 Disorder of refraction, unspecified
0.612 0.388 0.000
H52.6 Other disorders of refraction
0.612 0.388 0.000
H52.5 Disorders of accommodation
0.612 0.388 0.000
H52.4 Presbyopia
0.612 0.388 0.000
H52.0 Hypermetropia
0.612 0.388 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.612 0.388 0.000
E22 Hyperfunction of pituitary gland
0.611 0.388 0.000
E87.2 Acidosis
0.611 0.389 0.000
J46 Status asthmaticus
0.611 0.389 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.611 0.389 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.611 0.389 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.611 0.389 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.611 0.389 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.611 0.389 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.611 0.389 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.611 0.389 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.611 0.389 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.611 0.389 0.000
H18.8 Other specified disorders of cornea
0.610 0.389 0.000
K83.0 Cholangitis
0.610 0.390 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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