TreeWAS – Variant ID: rs1805576

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H53.0 Amblyopia ex anopsia	0.041	0.959	0.000
H53.9 Visual disturbance, unspecified	0.036	0.964	0.000
H53 Visual disturbances	0.036	0.964	0.000
H53.8 Other visual disturbances	0.029	0.971	0.000
H53-H54 Visual disturbances and blindness	0.027	0.973	0.000
H53.6 Night blindness	0.026	0.974	0.000
H53.5 Colour vision deficiencies	0.026	0.974	0.000
H53.3 Other disorders of binocular vision	0.026	0.974	0.000
H54 Blindness and low vision	0.026	0.974	0.000
H53.2 Diplopia	0.025	0.975	0.000
H54.7 Unspecified visual loss	0.024	0.976	0.000
H54.4 Blindness, one eye	0.024	0.976	0.000
H54.9 Unspecified visual impairment (binocular)	0.020	0.980	0.000
H54.0 Blindness, both eyes	0.019	0.981	0.000
H54.6 Unqualified visual loss, one eye	0.019	0.981	0.000
H53.4 Visual field defects	0.019	0.981	0.000
H54.3 Unqualified visual loss, both eyes	0.019	0.981	0.000
F20.0 Paranoid schizophrenia	0.000	0.981	0.019
H54.2 Low vision, both eyes	0.018	0.982	0.000
H54.1 Blindness, one eye, low vision, other eye	0.017	0.982	0.000
H54.5 Low vision, one eye	0.016	0.984	0.000
M25.86 Other specified joint disorders (Lower leg)	0.014	0.986	0.000
F20 Schizophrenia	0.000	0.988	0.012
F20.9 Schizophrenia, unspecified	0.000	0.990	0.010
H53.1 Subjective visual disturbances	0.010	0.990	0.000
F20.8 Other schizophrenia	0.000	0.991	0.009
F20.6 Simple schizophrenia	0.000	0.991	0.009
F20.4 Postschizophrenic depression	0.000	0.991	0.009
F20.3 Undifferentiated schizophrenia	0.000	0.991	0.009
F20.2 Catatonic schizophrenia	0.000	0.991	0.009
F20.1 Hebephrenic schizophrenia	0.000	0.991	0.009
E55.9 Vitamin D deficiency, unspecified	0.000	0.991	0.009
D04.7 Skin of lower limb, including hip	0.000	0.992	0.008
F20.5 Residual schizophrenia	0.000	0.993	0.007
R03.1 Nonspecific low blood-pressure reading	0.007	0.993	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.993	0.007
L29.9 Pruritus, unspecified	0.006	0.994	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.006	0.994	0.000
D04.4 Skin of scalp and neck	0.000	0.995	0.005
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.995	0.005
S82.40 Fracture of fibula alone (closed)	0.005	0.995	0.000
D04 Carcinoma in situ of skin	0.000	0.995	0.005
D04.6 Skin of upper limb, including shoulder	0.000	0.995	0.005
I12.0 Hypertensive renal disease with renal failure	0.005	0.995	0.000
E55 Vitamin D deficiency	0.000	0.996	0.004
F29 Unspecified nonorganic psychosis	0.000	0.996	0.004
T90.5 Sequelae of intracranial injury	0.004	0.996	0.000
F28 Other nonorganic psychotic disorders	0.000	0.996	0.004
F24 Induced delusional disorder	0.000	0.996	0.004
F21 Schizotypal disorder	0.000	0.996	0.004
F25 Schizoaffective disorders	0.000	0.996	0.004
M25.83 Other specified joint disorders (Forearm)	0.004	0.996	0.000
G43.9 Migraine, unspecified	0.004	0.996	0.000
M25.8 Other specified joint disorders	0.004	0.996	0.000
D04.9 Skin, unspecified	0.000	0.996	0.004
D04.8 Skin of other sites	0.000	0.996	0.004
D04.0 Skin of lip	0.000	0.996	0.004
E10.3 With ophthalmic complications	0.004	0.996	0.000
F23 Acute and transient psychotic disorders	0.000	0.996	0.004
N76.4 Abscess of vulva	0.004	0.996	0.000
F00 Dementia in Alzheimer's disease	0.000	0.996	0.004
F22 Persistent delusional disorders	0.000	0.996	0.004
Q82.8 Other specified congenital malformations of skin	0.004	0.996	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.004	0.996	0.000
Q79.6 Ehlers-Danlos syndrome	0.004	0.996	0.000
K09.0 Developmental odontogenic cysts	0.004	0.996	0.000
D04.2 Skin of ear and external auricular canal	0.000	0.996	0.003
F25.1 Schizoaffective disorder, depressive type	0.000	0.996	0.003
D04.1 Skin of eyelid, including canthus	0.000	0.996	0.003
T90.9 Sequelae of unspecified injury of head	0.003	0.997	0.000
R54 Senility	0.000	0.997	0.003
F25.0 Schizoaffective disorder, manic type	0.000	0.997	0.003
E55.0 Rickets, active	0.000	0.997	0.003
S31.1 Open wound of abdominal wall	0.003	0.997	0.000
T90 Sequelae of injuries of head	0.003	0.997	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.003	0.997	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.997	0.003
M25.88 Other specified joint disorders (Other)	0.003	0.997	0.000
F25.8 Other schizoaffective disorders	0.000	0.997	0.003
N76.2 Acute vulvitis	0.003	0.997	0.000
S31.0 Open wound of lower back and pelvis	0.003	0.997	0.000
S31 Open wound of abdomen, lower back and pelvis	0.003	0.997	0.000
K62.9 Disease of anus and rectum, unspecified	0.000	0.997	0.003
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.997	0.003
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.997	0.003
K60.2 Anal fissure, unspecified	0.003	0.997	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.003	0.997	0.000
M25.82 Other specified joint disorders (Upper arm)	0.003	0.997	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.003	0.997	0.000
F23.8 Other acute and transient psychotic disorders	0.000	0.997	0.003
F23.3 Other acute predominantly delusional psychotic disorders	0.000	0.997	0.003
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.997	0.003
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.997	0.003
D09.0 Bladder	0.000	0.997	0.003
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.997	0.003
T90.4 Sequelae of injury of eye and orbit	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
S31.4 Open wound of vagina and vulva	0.003	0.997	0.000
F22.9 Persistent delusional disorder, unspecified	0.000	0.997	0.003
F22.8 Other persistent delusional disorders	0.000	0.997	0.003
J32.9 Chronic sinusitis, unspecified	0.003	0.997	0.000
D04.3 Skin of other and unspecified parts of face	0.000	0.997	0.003
S31.8 Open wound of other and unspecified parts of abdomen	0.003	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
F25.2 Schizoaffective disorder, mixed type	0.000	0.997	0.003
Q43.8 Other specified congenital malformations of intestine	0.003	0.997	0.000
K09 Cysts of oral region, not elsewhere classified	0.003	0.997	0.000
F25.9 Schizoaffective disorder, unspecified	0.000	0.997	0.003
K09.8 Other cysts of oral region, not elsewhere classified	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Q82 Other congenital malformations of skin	0.003	0.997	0.000
K09.2 Other cysts of jaw	0.003	0.997	0.000
Q43.0 Meckel's diverticulum	0.003	0.997	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.997	0.003
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.003	0.997	0.000
N76.6 Ulceration of vulva	0.003	0.997	0.000
Z22.3 Carrier of other specified bacterial diseases	0.000	0.997	0.003
R03 Abnormal blood-pressure reading, without diagnosis	0.003	0.997	0.000
D09 Carcinoma in situ of other and unspecified sites	0.000	0.997	0.003
G82.2 Paraplegia, unspecified	0.003	0.997	0.000
Q39.4 Oesophageal web	0.003	0.997	0.000
N76 Other inflammation of vagina and vulva	0.003	0.997	0.000
D07.1 Vulva	0.000	0.997	0.003
T90.3 Sequelae of injury of cranial nerves	0.003	0.997	0.000
T90.1 Sequelae of open wound of head	0.003	0.997	0.000
T90.0 Sequelae of superficial injury of head	0.003	0.997	0.000
G82.1 Spastic paraplegia	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
F22.0 Delusional disorder	0.000	0.997	0.003
Y85 Sequelae of transport accidents	0.003	0.997	0.000
S89.9 Unspecified injury of lower leg	0.003	0.997	0.000
L29 Pruritus	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.002	0.997	0.000
S31.5 Open wound of other and unspecified external genital organs	0.002	0.997	0.000
S31.3 Open wound of scrotum and testes	0.002	0.997	0.000
S31.2 Open wound of penis	0.002	0.997	0.000
Q43.3 Congenital malformations of intestinal fixation	0.002	0.997	0.000
K12.1 Other forms of stomatitis	0.000	0.997	0.003
S69.9 Unspecified injury of wrist and hand	0.003	0.997	0.000
D04.5 Skin of trunk	0.000	0.997	0.002
Q39.6 Diverticulum of oesophagus	0.002	0.997	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.997	0.003
N76.5 Ulceration of vagina	0.002	0.997	0.000
U80.0 Penicillin resistant agent	0.000	0.997	0.003
N42.9 Disorder of prostate, unspecified	0.003	0.997	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.002	0.997	0.000
Q43.7 Persistent cloaca	0.002	0.997	0.000
Q43.6 Congenital fistula of rectum and anus	0.002	0.997	0.000
Q43.5 Ectopic anus	0.002	0.997	0.000
Q43.4 Duplication of intestine	0.002	0.997	0.000
Q43.2 Other congenital functional disorders of colon	0.002	0.997	0.000
Q43.1 Hirschsprung's disease	0.002	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.997	0.000
L29.8 Other pruritus	0.002	0.998	0.000
G82 Paraplegia and tetraplegia	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.002	0.998	0.000
I45.6 Preexcitation syndrome	0.002	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.002	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.998	0.000
K09.9 Cyst of oral region, unspecified	0.002	0.998	0.000
D09.1 Other and unspecified urinary organs	0.000	0.998	0.002
Q39.9 Congenital malformation of oesophagus, unspecified	0.002	0.998	0.000
Q39.8 Other congenital malformations of oesophagus	0.002	0.998	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.998	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.002	0.998	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.002	0.998	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.002	0.998	0.000
Q39.0 Atresia of oesophagus without fistula	0.002	0.998	0.000
D07.5 Prostate	0.000	0.998	0.002
Q82.9 Congenital malformation of skin, unspecified	0.002	0.998	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.002	0.998	0.000
Q82.3 Incontinentia pigmenti	0.002	0.998	0.000
Q82.2 Mastocytosis	0.002	0.998	0.000
Q82.1 Xeroderma pigmentosum	0.002	0.998	0.000
Q82.0 Hereditary lymphoedema	0.002	0.998	0.000
D00-D09 In situ neoplasms	0.000	0.998	0.002
S00.9 Superficial injury of head, part unspecified	0.000	0.998	0.002
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
K80.8 Other cholelithiasis	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.998	0.000
Q79.4 Prune belly syndrome	0.002	0.998	0.000
Q79.3 Gastroschisis	0.002	0.998	0.000
Q79.2 Exomphalos	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
Q79.0 Congenital diaphragmatic hernia	0.002	0.998	0.000
S82.4 Fracture of fibula alone	0.002	0.998	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
M25.84 Other specified joint disorders (Hand)	0.002	0.998	0.000
N76.3 Subacute and chronic vulvitis	0.002	0.998	0.000
D09.9 Carcinoma in situ, unspecified	0.000	0.998	0.002
D09.7 Carcinoma in situ of other specified sites	0.000	0.998	0.002
D09.3 Thyroid and other endocrine glands	0.000	0.998	0.002
D09.2 Eye	0.000	0.998	0.002
T90.8 Sequelae of other specified injuries of head	0.002	0.998	0.000
G82.5 Tetraplegia, unspecified	0.002	0.998	0.000
N30.3 Trigonitis	0.000	0.998	0.002
Q44.7 Other congenital malformations of liver	0.002	0.998	0.000
Q44.4 Choledochal cyst	0.002	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.998	0.000
Q44.2 Atresia of bile ducts	0.002	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
Y85.0 Sequelae of motor-vehicle accident	0.002	0.998	0.000
L29.3 Anogenital pruritus, unspecified	0.002	0.998	0.000
L29.1 Pruritus scroti	0.002	0.998	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.998	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.998	0.000
Q45.1 Annular pancreas	0.002	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.998	0.000
Q82.5 Congenital nonneoplastic naevus	0.002	0.998	0.000
D05.1 Intraductal carcinoma in situ	0.000	0.998	0.002
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
N76.1 Subacute and chronic vaginitis	0.002	0.998	0.000
Q40.2 Other specified congenital malformations of stomach	0.002	0.998	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.000	0.998	0.002
U80 Agent resistant to penicillin and related antibiotics	0.000	0.998	0.002
D07.6 Other and unspecified male genital organs	0.000	0.998	0.002
D07.3 Other and unspecified female genital organs	0.000	0.998	0.002
D07.0 Endometrium	0.000	0.998	0.002
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.000	0.998	0.002
Q38.6 Other congenital malformations of mouth	0.002	0.998	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.998	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.998	0.000
Q40.1 Congenital hiatus hernia	0.002	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.002	0.998	0.000
I12 Hypertensive renal disease	0.002	0.998	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.002	0.998	0.000
L29.0 Pruritus ani	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
G82.3 Flaccid tetraplegia	0.002	0.998	0.000
G82.0 Flaccid paraplegia	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.002	0.998	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.002	0.998	0.000
N82.8 Other female genital tract fistulae	0.002	0.998	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.002	0.998	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.002	0.998	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.002	0.998	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.002	0.998	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.002	0.998	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.002	0.998	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.002	0.998	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.002	0.998	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.002	0.998	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.002	0.998	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.002	0.998	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.000	0.998	0.002
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
D00.0 Lip, oral cavity and pharynx	0.000	0.998	0.002
D07.4 Penis	0.000	0.998	0.002
D07.2 Vagina	0.000	0.998	0.002
G82.4 Spastic tetraplegia	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.998	0.002
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.998	0.000
Q84 Other congenital malformations of integument	0.002	0.998	0.000
Q81 Epidermolysis bullosa	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.002	0.998	0.000
Q38.8 Other congenital malformations of pharynx	0.002	0.998	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.002	0.998	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.002	0.998	0.000
Q38.3 Other congenital malformations of tongue	0.002	0.998	0.000
Q38.2 Macroglossia	0.002	0.998	0.000
Q38.1 Ankyloglossia	0.002	0.998	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.002	0.998	0.000
U80.1 Methicillin resistant agent	0.000	0.998	0.002
S82.41 Fracture of fibula alone (open)	0.002	0.998	0.000
D05.7 Other carcinoma in situ of breast	0.000	0.998	0.002
Q87.4 Marfan's syndrome	0.002	0.998	0.000
Y60.0 During surgical operation	0.000	0.998	0.002
K72.0 Acute and subacute hepatic failure	0.000	0.998	0.002
F80.1 Expressive language disorder	0.000	0.998	0.002
I49.4 Other and unspecified premature depolarisation	0.000	0.998	0.002
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
D22.0 Melanocytic naevi of lip	0.002	0.998	0.000
F17.2 Dependence syndrome	0.000	0.998	0.002
N76.0 Acute vaginitis	0.000	0.998	0.001
N82.4 Other female intestinal-genital tract fistulae	0.002	0.998	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.002	0.998	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.002	0.998	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.002	0.998	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.002	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.002	0.998	0.000
D05 Carcinoma in situ of breast	0.000	0.998	0.002
Q83.3 Accessory nipple	0.002	0.998	0.000
Q83.1 Accessory breast	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
Y86 Sequelae of other accidents	0.002	0.998	0.000
D00.2 Stomach	0.000	0.998	0.002
D00.1 Oesophagus	0.000	0.998	0.002
N82.3 Fistula of vagina to large intestine	0.002	0.998	0.000
D01.3 Anus and anal canal	0.001	0.998	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.001	0.998	0.001
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
N82 Fistulae involving female genital tract	0.002	0.998	0.000
Q83.9 Congenital malformation of breast, unspecified	0.002	0.998	0.000
Q83.2 Absent nipple	0.002	0.998	0.000
Q83.0 Congenital absence of breast with absent nipple	0.002	0.998	0.000
D02.0 Larynx	0.000	0.998	0.002
R61.9 Hyperhidrosis, unspecified	0.000	0.998	0.002
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.002	0.998	0.000
M13.98 Arthritis, unspecified (Other)	0.000	0.998	0.002
D02.4 Respiratory system, unspecified	0.000	0.998	0.002
D02.3 Other parts of respiratory system	0.000	0.998	0.002
D02.2 Bronchus and lung	0.000	0.998	0.002
D02.1 Trachea	0.000	0.998	0.002
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
Q80.9 Congenital ichthyosis, unspecified	0.001	0.998	0.000
Q80.8 Other congenital ichthyosis	0.001	0.998	0.000
Q80.4 Harlequin foetus	0.001	0.998	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.001	0.998	0.000
Q80.2 Lamellar ichthyosis	0.001	0.998	0.000
Q80.1 X-linked ichthyosis	0.001	0.998	0.000
Q80.0 Ichthyosis vulgaris	0.001	0.998	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.001	0.998	0.000
Q81.8 Other epidermolysis bullosa	0.001	0.998	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.001	0.998	0.000
Q81.1 Epidermolysis bullosa letalis	0.001	0.998	0.000
Q81.0 Epidermolysis bullosa simplex	0.001	0.998	0.000
Q84.9 Congenital malformation of integument, unspecified	0.001	0.998	0.000
Q84.8 Other specified congenital malformations of integument	0.001	0.998	0.000
Q84.6 Other congenital malformations of nails	0.001	0.998	0.000
Q84.5 Enlarged and hypertrophic nails	0.001	0.998	0.000
Q84.4 Congenital leukonychia	0.001	0.998	0.000
Q84.3 Anonychia	0.001	0.998	0.000
Q84.2 Other congenital malformations of hair	0.001	0.998	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.001	0.998	0.000
Q84.0 Congenital alopecia	0.001	0.998	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.001	0.998	0.000
Q86.2 Dysmorphism due to warfarin	0.001	0.998	0.000
Q86.1 Foetal hydantoin syndrome	0.001	0.998	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.001	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
Q83.8 Other congenital malformations of breast	0.001	0.998	0.000
Q85.9 Phakomatosis, unspecified	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
D68.9 Coagulation defect, unspecified	0.000	0.998	0.002
H72.0 Central perforation of tympanic membrane	0.000	0.998	0.002
Q38.7 Pharyngeal pouch	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.001	0.998	0.000
Q67.7 Pectus carinatum	0.001	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.001	0.998	0.000
Q67.3 Plagiocephaly	0.001	0.998	0.000
Q67.2 Dolichocephaly	0.001	0.998	0.000
Q67.1 Compression facies	0.001	0.998	0.000
Q67.0 Facial asymmetry	0.001	0.998	0.000
S69.7 Multiple injuries of wrist and hand	0.002	0.998	0.000
Y88 Sequelae of surgical and medical care as external cause	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.002	0.998	0.000
N82.0 Vesicovaginal fistula	0.002	0.998	0.000
Q74.1 Congenital malformation of knee	0.001	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
I12.9 Hypertensive renal disease without renal failure	0.002	0.998	0.000
N76.8 Other specified inflammation of vagina and vulva	0.001	0.998	0.000
N82.5 Female genital tract-skin fistulae	0.002	0.998	0.000
F80 Specific developmental disorders of speech and language	0.000	0.998	0.002
M79.67 Pain in limb (Ankle and foot)	0.002	0.998	0.000
F84.5 Asperger's syndrome	0.000	0.998	0.001
Q74.9 Unspecified congenital malformation of limb(s)	0.001	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.001	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.001	0.998	0.000
Y65.8 Other specified misadventures during surgical and medical care	0.000	0.998	0.002
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998	0.000
D01.9 Digestive organ, unspecified	0.001	0.998	0.001
D01.7 Other specified digestive organs	0.001	0.998	0.001
D01.5 Liver, gallbladder and bile ducts	0.001	0.998	0.001
D01.4 Other and unspecified parts of intestine	0.001	0.998	0.001
D01.1 Rectosigmoid junction	0.001	0.998	0.001
D59.8 Other acquired haemolytic anaemias	0.001	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.001	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.001	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.001	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.001	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.001	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.001	0.998	0.000
H81.1 Benign paroxysmal vertigo	0.000	0.998	0.002
N82.9 Female genital tract fistula, unspecified	0.001	0.998	0.000
Q89.9 Congenital malformation, unspecified	0.001	0.998	0.000
Q89.8 Other specified congenital malformations	0.001	0.998	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.001	0.998	0.000
Q89.4 Conjoined twins	0.001	0.998	0.000
Q89.3 Situs inversus	0.001	0.998	0.000
Q89.1 Congenital malformations of adrenal gland	0.001	0.998	0.000
Q89.0 Congenital malformations of spleen	0.001	0.998	0.000
D56.3 Thalassaemia trait	0.001	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.002	0.998	0.000
N82.2 Fistula of vagina to small intestine	0.001	0.998	0.000
N82.1 Other female urinary-genital tract fistulae	0.001	0.998	0.000
Q18.1 Preauricular sinus and cyst	0.001	0.998	0.000
Q85.1 Tuberous sclerosis	0.001	0.998	0.000
Q78 Other osteochondrodysplasias	0.001	0.998	0.000
D01.0 Colon	0.001	0.998	0.001
S69 Other and unspecified injuries of wrist and hand	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.998	0.002
D01.2 Rectum	0.001	0.998	0.001
Q85.8 Other phakomatoses, not elsewhere classified	0.001	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.001	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.001	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.001	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.001	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.001	0.998	0.000
Q68.3 Congenital bowing of femur	0.001	0.998	0.000
Q68.2 Congenital deformity of knee	0.001	0.998	0.000
Q68.1 Congenital deformity of hand	0.001	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.001	0.998	0.000
Q69.9 Polydactyly, unspecified	0.001	0.998	0.000
Q69.2 Accessory toe(s)	0.001	0.998	0.000
Q69.1 Accessory thumb(s)	0.001	0.998	0.000
Q69.0 Accessory finger(s)	0.001	0.998	0.000
Q70.9 Syndactyly, unspecified	0.001	0.998	0.000
Q70.4 Polysyndactyly	0.001	0.998	0.000
Q70.3 Webbed toes	0.001	0.998	0.000
Q70.2 Fused toes	0.001	0.998	0.000
Q70.1 Webbed fingers	0.001	0.998	0.000
Q70.0 Fused fingers	0.001	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.001	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.001	0.998	0.000
Q71.6 Lobster-claw hand	0.001	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.001	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.001	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.001	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.001	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.001	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.001	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.001	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.001	0.998	0.000
Q72.7 Split foot	0.001	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.001	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.001	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.001	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.001	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.001	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.001	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.001	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.001	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.001	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.001	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.001	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.001	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.001	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.001	0.998	0.000
Q75.3 Macrocephaly	0.001	0.998	0.000
Q75.2 Hypertelorism	0.001	0.998	0.000
Q75.1 Craniofacial dysostosis	0.001	0.998	0.000
Q75.0 Craniosynostosis	0.001	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.001	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.001	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.001	0.998	0.000
Q77.5 Diastrophic dysplasia	0.001	0.998	0.000
Q77.4 Achondroplasia	0.001	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.001	0.998	0.000
Q77.2 Short rib syndrome	0.001	0.998	0.000
Q77.1 Thanatophoric short stature	0.001	0.998	0.000
Q77.0 Achondrogenesis	0.001	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.001	0.999	0.000
W25.9 Unspecified place	0.001	0.999	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.001	0.999	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.001	0.999	0.000
Q54.1 Hypospadias, penile	0.001	0.999	0.000
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.001	0.999	0.000
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.001	0.999	0.000
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.001	0.999	0.000
F84 Pervasive developmental disorders	0.000	0.999	0.001
Q65.9 Congenital deformity of hip, unspecified	0.001	0.999	0.000
Q65.6 Unstable hip	0.001	0.999	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.001	0.999	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.001	0.999	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.001	0.999	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.001	0.999	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.001	0.999	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.001	0.999	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.001	0.999	0.000
D56 Thalassaemia	0.001	0.999	0.000
Q18 Other congenital malformations of face and neck	0.001	0.999	0.000
Y89 Sequelae of other external causes	0.001	0.999	0.000
F80.9 Developmental disorder of speech and language, unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations