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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs181660893
log Bayes Factor = 3.37336
Chromosome 2   position 82,026,934  (GRCh37) Explore rs181660893 on Ensembl!
Variant rs181660893 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
# Top node
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
I25 Chronic ischaemic heart disease
0.990 0.010 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.985 0.015 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.978 0.022 0.000
Chapter VIII Diseases of the ear and mastoid process
0.974 0.026 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.973 0.027 0.000
D50-D53 Nutritional anaemias
0.970 0.030 0.000
D50 Iron deficiency anaemia
0.965 0.035 0.000
I20 Angina pectoris
0.958 0.042 0.000
I21 Acute myocardial infarction
0.949 0.051 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.949 0.051 0.000
T81 Complications of procedures, not elsewhere classified
0.946 0.054 0.000
D50.8 Other iron deficiency anaemias
0.939 0.061 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.931 0.069 0.000
D50.9 Iron deficiency anaemia, unspecified
0.920 0.080 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.918 0.082 0.000
I20.9 Angina pectoris, unspecified
0.915 0.085 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.908 0.092 0.000
I21.4 Acute subendocardial myocardial infarction
0.905 0.095 0.000
Chapter V Mental and behavioural disorders
0.903 0.097 0.000
H90-H95 Other disorders of ear
0.903 0.097 0.000
I60-I69 Cerebrovascular diseases
0.902 0.098 0.000
I73 Other peripheral vascular diseases
0.896 0.104 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.894 0.106 0.000
H65-H75 Diseases of middle ear and mastoid
0.893 0.107 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.876 0.124 0.000
I77 Other disorders of arteries and arterioles
0.867 0.133 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.858 0.142 0.000
F30-F39 Mood [affective] disorders
0.848 0.152 0.000
Chapter I Certain infectious and parasitic diseases
0.829 0.171 0.000
Chapter XI Diseases of the digestive system
0.818 0.182 0.000
E00-E07 Disorders of thyroid gland
0.817 0.183 0.000
I73.9 Peripheral vascular disease, unspecified
0.814 0.186 0.000
F32 Depressive episode
0.813 0.187 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.807 0.193 0.000
I63 Cerebral infarction
0.803 0.197 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.798 0.202 0.000
H72 Perforation of tympanic membrane
0.795 0.204 0.000
I77.1 Stricture of artery
0.791 0.209 0.000
I25.2 Old myocardial infarction
0.789 0.211 0.000
I24 Other acute ischaemic heart diseases
0.786 0.214 0.000
I20.8 Other forms of angina pectoris
0.781 0.219 0.000
S60-S69 Injuries to the wrist and hand
0.781 0.219 0.000
F32.9 Depressive episode, unspecified
0.779 0.221 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.778 0.221 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.775 0.225 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.774 0.226 0.000
S40-S49 Injuries to the shoulder and upper arm
0.771 0.229 0.000
S70-S79 Injuries to the hip and thigh
0.767 0.233 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.762 0.238 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.759 0.241 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.759 0.241 0.000
H92 Otalgia and effusion of ear
0.757 0.243 0.000
I71 Aortic aneurysm and dissection
0.756 0.244 0.000
I74 Arterial embolism and thrombosis
0.755 0.245 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.755 0.245 0.000
H90 Conductive and sensorineural hearing loss
0.754 0.245 0.000
H91 Other hearing loss
0.750 0.250 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.748 0.252 0.000
I20.1 Angina pectoris with documented spasm
0.746 0.254 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.744 0.256 0.000
K21 Gastro-oesophageal reflux disease
0.740 0.260 0.000
H80-H83 Diseases of inner ear
0.737 0.263 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.734 0.266 0.000
A00-A09 Intestinal infectious diseases
0.733 0.267 0.000
H71 Cholesteatoma of middle ear
0.733 0.267 0.000
S50-S59 Injuries to the elbow and forearm
0.732 0.268 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.732 0.268 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.730 0.270 0.000
Chapter X Diseases of the respiratory system
0.729 0.271 0.000
I25.1 Atherosclerotic heart disease
0.728 0.272 0.000
I30-I52 Other forms of heart disease
0.727 0.273 0.000
I73.0 Raynaud's syndrome
0.726 0.274 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.726 0.274 0.000
K30 Dyspepsia
0.724 0.276 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.723 0.277 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.722 0.278 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.721 0.279 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.720 0.280 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.719 0.281 0.000
S20-S29 Injuries to the thorax
0.718 0.282 0.000
S90-S99 Injuries to the ankle and foot
0.718 0.282 0.000
D80-D89 Certain disorders involving the immune mechanism
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
Chapter XXII Codes for special purposes
0.716 0.284 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
K29 Gastritis and duodenitis
0.716 0.284 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.714 0.286 0.000
T79-T79 Certain early complications of trauma
0.714 0.286 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.714 0.286 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
S10-S19 Injuries to the neck
0.714 0.286 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.713 0.287 0.000
T66-T78 Other and unspecified effects of external causes
0.711 0.289 0.000
I63.9 Cerebral infarction, unspecified
0.711 0.289 0.000
I25.6 Silent myocardial ischaemia
0.709 0.290 0.000
I25.5 Ischaemic cardiomyopathy
0.709 0.290 0.000
I25.4 Coronary artery aneurysm
0.709 0.290 0.000
I25.3 Aneurysm of heart
0.709 0.290 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.709 0.290 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.709 0.291 0.000
I62 Other nontraumatic intracranial haemorrhage
0.709 0.291 0.000
T87 Complications peculiar to reattachment and amputation
0.706 0.293 0.000
T86 Failure and rejection of transplanted organs and tissues
0.706 0.293 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.706 0.293 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.706 0.293 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.705 0.294 0.000
D55-D59 Haemolytic anaemias
0.701 0.299 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.701 0.299 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.700 0.300 0.000
H60-H62 Diseases of external ear
0.698 0.302 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.698 0.302 0.000
I78 Diseases of capillaries
0.698 0.302 0.000
I72 Other aneurysm
0.698 0.302 0.000
I70 Atherosclerosis
0.698 0.302 0.000
Chapter VII Diseases of the eye and adnexa
0.697 0.303 0.000
I22 Subsequent myocardial infarction
0.696 0.304 0.000
D53 Other nutritional anaemias
0.695 0.304 0.000
D52 Folate deficiency anaemia
0.695 0.304 0.000
Chapter XX External causes of morbidity and mortality
0.693 0.307 0.000
E06 Thyroiditis
0.693 0.307 0.000
D50.1 Sideropenic dysphagia
0.692 0.308 0.000
E10-E14 Diabetes mellitus
0.691 0.309 0.000
D60-D64 Aplastic and other anaemias
0.690 0.310 0.000
I05-I09 Chronic rheumatic heart diseases
0.690 0.310 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.682 0.318 0.000
S00-S09 Injuries to the head
0.681 0.319 0.000
D51 Vitamin B12 deficiency anaemia
0.681 0.319 0.000
K29.6 Other gastritis
0.681 0.319 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.680 0.319 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.680 0.319 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.680 0.319 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.680 0.320 0.000
T81.9 Unspecified complication of procedure
0.678 0.321 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.678 0.321 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.678 0.321 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.678 0.321 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.678 0.321 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.678 0.322 0.000
K35-K38 Diseases of appendix
0.674 0.326 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.674 0.326 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.673 0.327 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.671 0.329 0.000
E05.9 Thyrotoxicosis, unspecified
0.670 0.330 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.669 0.331 0.000
I21.9 Acute myocardial infarction, unspecified
0.668 0.332 0.000
H66 Suppurative and unspecified otitis media
0.668 0.332 0.000
E20-E35 Disorders of other endocrine glands
0.662 0.338 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.662 0.338 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.656 0.344 0.000
I61 Intracerebral haemorrhage
0.654 0.346 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.651 0.349 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.651 0.349 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.651 0.349 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.651 0.349 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.651 0.349 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.651 0.349 0.000
T43.2 Other and unspecified antidepressants
0.651 0.349 0.000
H73 Other disorders of tympanic membrane
0.649 0.351 0.000
F99-F99 Unspecified mental disorder
0.647 0.353 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.647 0.353 0.000
F80-F89 Disorders of psychological development
0.647 0.353 0.000
F70-F79 Mental retardation
0.647 0.353 0.000
F60-F69 Disorders of adult personality and behaviour
0.647 0.353 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.647 0.353 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.647 0.353 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.646 0.353 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.646 0.353 0.000
I60 Subarachnoid haemorrhage
0.646 0.353 0.000
E50-E64 Other nutritional deficiencies
0.646 0.354 0.000
H93 Other disorders of ear, not elsewhere classified
0.645 0.355 0.000
S80-S89 Injuries to the knee and lower leg
0.644 0.356 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.643 0.357 0.000
I73.8 Other specified peripheral vascular diseases
0.642 0.357 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.642 0.357 0.000
A04 Other bacterial intestinal infections
0.642 0.358 0.000
H91.9 Hearing loss, unspecified
0.641 0.359 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.641 0.359 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.641 0.359 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.641 0.359 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.641 0.359 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.641 0.359 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.641 0.359 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.641 0.359 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.641 0.359 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.641 0.359 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.641 0.359 0.000
T36 Poisoning by systemic antibiotics
0.641 0.359 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.640 0.360 0.000
H74 Other disorders of middle ear and mastoid
0.640 0.360 0.000
H70 Mastoiditis and related conditions
0.640 0.360 0.000
H69 Other disorders of Eustachian tube
0.640 0.360 0.000
H68 Eustachian salpingitis and obstruction
0.640 0.360 0.000
H67 Otitis media in diseases classified elsewhere
0.640 0.360 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.640 0.360 0.000
I24.8 Other forms of acute ischaemic heart disease
0.636 0.364 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.636 0.364 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.633 0.367 0.000
L20-L30 Dermatitis and eczema
0.631 0.369 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.631 0.369 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.630 0.369 0.000
E40-E46 Malnutrition
0.628 0.372 0.000
K13 Other diseases of lip and oral mucosa
0.628 0.372 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.627 0.373 0.000
B35-B49 Mycoses
0.626 0.373 0.000
H90.2 Conductive hearing loss, unspecified
0.625 0.375 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.622 0.377 0.000
F32.1 Moderate depressive episode
0.622 0.378 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.622 0.378 0.000
I77.8 Other specified disorders of arteries and arterioles
0.622 0.378 0.000
I77.6 Arteritis, unspecified
0.622 0.378 0.000
I77.5 Necrosis of artery
0.622 0.378 0.000
I77.4 Coeliac artery compression syndrome
0.622 0.378 0.000
I77.3 Arterial fibromuscular dysplasia
0.622 0.378 0.000
I77.2 Rupture of artery
0.622 0.378 0.000
I77.0 Arteriovenous fistula, acquired
0.622 0.378 0.000
E04 Other non-toxic goitre
0.620 0.380 0.000
H65 Nonsuppurative otitis media
0.619 0.381 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.618 0.382 0.000
H92.0 Otalgia
0.616 0.384 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.616 0.384 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.616 0.384 0.000
L10-L14 Bullous disorders
0.615 0.385 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.611 0.389 0.000
F38 Other mood [affective] disorders
0.608 0.392 0.000
F34 Persistent mood [affective] disorders
0.608 0.392 0.000
F33 Recurrent depressive disorder
0.608 0.392 0.000
F30 Manic episode
0.608 0.392 0.000
F39 Unspecified mood [affective] disorder
0.608 0.392 0.000
F41 Other anxiety disorders
0.608 0.392 0.000
L40-L45 Papulosquamous disorders
0.607 0.393 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.605 0.395 0.000
E06.3 Autoimmune thyroiditis
0.604 0.396 0.000
S72 Fracture of femur
0.603 0.397 0.000
S42 Fracture of shoulder and upper arm
0.603 0.397 0.000
T88.4 Failed or difficult intubation
0.602 0.397 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.600 0.400 0.000
K27 Peptic ulcer, site unspecified
0.600 0.400 0.000
F03 Unspecified dementia
0.600 0.400 0.000
L50-L54 Urticaria and erythema
0.600 0.400 0.000
J30-J39 Other diseases of upper respiratory tract
0.599 0.401 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.599 0.401 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.598 0.402 0.000
H92.1 Otorrhoea
0.598 0.402 0.000
K26 Duodenal ulcer
0.596 0.404 0.000
B99-B99 Other infectious diseases
0.594 0.405 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.594 0.405 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.594 0.405 0.000
B65-B83 Helminthiases
0.594 0.405 0.000
B50-B64 Protozoal diseases
0.594 0.405 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.594 0.405 0.000
B15-B19 Viral hepatitis
0.594 0.405 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.594 0.405 0.000
A80-A89 Viral infections of the central nervous system
0.594 0.405 0.000
A75-A79 Rickettsioses
0.594 0.405 0.000
A70-A74 Other diseases caused by chlamydiae
0.594 0.405 0.000
A65-A69 Other spirochaetal diseases
0.594 0.405 0.000
A20-A28 Certain zoonotic bacterial diseases
0.594 0.405 0.000
A15-A19 Tuberculosis
0.594 0.405 0.000
I20.0 Unstable angina
0.592 0.408 0.000
K35 Acute appendicitis
0.591 0.409 0.000
H81 Disorders of vestibular function
0.591 0.409 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.586 0.414 0.000
E07 Other disorders of thyroid
0.586 0.414 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.586 0.414 0.000
E00 Congenital iodine-deficiency syndrome
0.586 0.414 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.586 0.414 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.585 0.415 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.585 0.415 0.000
F32.8 Other depressive episodes
0.583 0.417 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.583 0.417 0.000
F32.0 Mild depressive episode
0.583 0.417 0.000
K31 Other diseases of stomach and duodenum
0.583 0.417 0.000
L03 Cellulitis
0.582 0.418 0.000
K07 Dentofacial anomalies [including malocclusion]
0.582 0.418 0.000
H90.5 Sensorineural hearing loss, unspecified
0.580 0.420 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.579 0.421 0.000
A30-A49 Other bacterial diseases
0.578 0.422 0.000
S64 Injury of nerves at wrist and hand level
0.578 0.422 0.000
K25 Gastric ulcer
0.577 0.423 0.000
I63.8 Other cerebral infarction
0.575 0.424 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.575 0.424 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.575 0.424 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.575 0.424 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.575 0.424 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.575 0.424 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.575 0.424 0.000
F31 Bipolar affective disorder
0.573 0.426 0.000
K28 Gastrojejunal ulcer
0.572 0.428 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.572 0.428 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.570 0.429 0.000
H72.8 Other perforations of tympanic membrane
0.570 0.430 0.000
H72.2 Other marginal perforations of tympanic membrane
0.570 0.430 0.000
H72.1 Attic perforation of tympanic membrane
0.570 0.430 0.000
H72.0 Central perforation of tympanic membrane
0.570 0.430 0.000
J34 Other disorders of nose and nasal sinuses
0.570 0.430 0.000
K90-K93 Other diseases of the digestive system
0.569 0.431 0.000
I49 Other cardiac arrhythmias
0.569 0.431 0.000
J00-J06 Acute upper respiratory infections
0.568 0.432 0.000
K22 Other diseases of oesophagus
0.567 0.433 0.000
L08 Other local infections of skin and subcutaneous tissue
0.567 0.433 0.000
I67 Other cerebrovascular diseases
0.566 0.434 0.000
K12 Stomatitis and related lesions
0.565 0.435 0.000
E14 Unspecified diabetes mellitus
0.565 0.435 0.000
I24.1 Dressler's syndrome
0.564 0.436 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.564 0.436 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.562 0.438 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.561 0.439 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.560 0.439 0.000
I38 Endocarditis, valve unspecified
0.560 0.440 0.000
S69 Other and unspecified injuries of wrist and hand
0.560 0.440 0.000
S68 Traumatic amputation of wrist and hand
0.560 0.440 0.000
S67 Crushing injury of wrist and hand
0.560 0.440 0.000
S65 Injury of blood vessels at wrist and hand level
0.560 0.440 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.560 0.440 0.000
S60 Superficial injury of wrist and hand
0.560 0.440 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.559 0.440 0.000
E03 Other hypothyroidism
0.559 0.441 0.000
T43.9 Psychotropic drug, unspecified
0.558 0.442 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.558 0.442 0.000
T43.6 Psychostimulants with abuse potential
0.558 0.442 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.558 0.442 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.558 0.442 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.558 0.442 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.558 0.442 0.000
J09-J18 Influenza and pneumonia
0.558 0.442 0.000
I65.2 Occlusion and stenosis of carotid artery
0.555 0.445 0.000
I51 Complications and ill-defined descriptions of heart disease
0.555 0.445 0.000
L05 Pilonidal cyst
0.555 0.445 0.000
L04 Acute lymphadenitis
0.555 0.445 0.000
L01 Impetigo
0.555 0.445 0.000
L00 Staphylococcal scalded skin syndrome
0.555 0.445 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.553 0.447 0.000
S48 Traumatic amputation of shoulder and upper arm
0.553 0.447 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.553 0.447 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.553 0.447 0.000
S44 Injury of nerves at shoulder and upper arm level
0.553 0.447 0.000
S41 Open wound of shoulder and upper arm
0.553 0.447 0.000
S40 Superficial injury of shoulder and upper arm
0.553 0.447 0.000
S47 Crushing injury of shoulder and upper arm
0.553 0.447 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.550 0.450 0.000
S79 Other and unspecified injuries of hip and thigh
0.550 0.450 0.000
S78 Traumatic amputation of hip and thigh
0.550 0.450 0.000
S77 Crushing injury of hip and thigh
0.550 0.450 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.550 0.450 0.000
S75 Injury of blood vessels at hip and thigh level
0.550 0.450 0.000
S74 Injury of nerves at hip and thigh level
0.550 0.450 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.550 0.450 0.000
S71 Open wound of hip and thigh
0.550 0.450 0.000
S70 Superficial injury of hip and thigh
0.550 0.450 0.000
B25-B34 Other viral diseases
0.549 0.450 0.000
B95-B98 Bacterial, viral and other infectious agents
0.549 0.451 0.000
K29.7 Gastritis, unspecified
0.549 0.451 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.548 0.452 0.000
I45 Other conduction disorders
0.547 0.453 0.000
T88.9 Complication of surgical and medical care, unspecified
0.546 0.453 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.546 0.453 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.546 0.453 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.546 0.453 0.000
T88.5 Other complications of anaesthesia
0.546 0.453 0.000
T88.3 Malignant hyperthermia due to anaesthesis
0.546 0.453 0.000
T88.2 Shock due to anaesthesia
0.546 0.453 0.000
T88.1 Other complications following immunisation, not elsewhere classified
0.546 0.453 0.000
T88.0 Infection following immunisation
0.546 0.453 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.545 0.455 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.545 0.455 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.544 0.456 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.544 0.456 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.544 0.456 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.544 0.456 0.000
T85.2 Mechanical complication of intraocular lens
0.544 0.456 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.544 0.456 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.544 0.456 0.000
I31 Other diseases of pericardium
0.544 0.456 0.000
S52 Fracture of forearm
0.543 0.456 0.000
K04 Diseases of pulp and periapical tissues
0.544 0.456 0.000
H92.2 Otorrhagia
0.543 0.457 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.542 0.458 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.542 0.458 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.542 0.458 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.542 0.458 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.542 0.458 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.542 0.458 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.542 0.458 0.000
I71.0 Dissection of aorta [any part]
0.542 0.458 0.000
S62 Fracture at wrist and hand level
0.541 0.459 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.541 0.459 0.000
I74.8 Embolism and thrombosis of other arteries
0.541 0.459 0.000
I74.5 Embolism and thrombosis of iliac artery
0.541 0.459 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.541 0.459 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.541 0.459 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.541 0.459 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.541 0.459 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.541 0.459 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.541 0.459 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.541 0.459 0.000
T42.3 Barbiturates
0.541 0.459 0.000
T42.2 Succinimides and oxazolidinediones
0.541 0.459 0.000
T42.1 Iminostilbenes
0.541 0.459 0.000
T42.0 Hydantoin derivatives
0.541 0.459 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.541 0.459 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.541 0.459 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.541 0.459 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.541 0.459 0.000
H90.3 Sensorineural hearing loss, bilateral
0.541 0.459 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.541 0.459 0.000
H90.0 Conductive hearing loss, bilateral
0.541 0.459 0.000
K01 Embedded and impacted teeth
0.540 0.460 0.000
T31 Burns classified according to extent of body surface involved
0.539 0.461 0.000
T42.4 Benzodiazepines
0.538 0.461 0.000
H91.8 Other specified hearing loss
0.538 0.462 0.000
H91.3 Deaf mutism, not elsewhere classified
0.538 0.462 0.000
H91.2 Sudden idiopathic hearing loss
0.538 0.462 0.000
H91.1 Presbycusis
0.538 0.462 0.000
H91.0 Ototoxic hearing loss
0.538 0.462 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.537 0.463 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.537 0.463 0.000
K29.0 Acute haemorrhagic gastritis
0.537 0.463 0.000
A04.8 Other specified bacterial intestinal infections
0.535 0.465 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.534 0.466 0.000
K08 Other disorders of teeth and supporting structures
0.532 0.468 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.531 0.469 0.000
D86 Sarcoidosis
0.529 0.471 0.000
H80 Otosclerosis
0.528 0.472 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.528 0.472 0.000
T82.1 Mechanical complication of cardiac electronic device
0.528 0.472 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.527 0.473 0.000
E05.8 Other thyrotoxicosis
0.527 0.473 0.000
E05.5 Thyroid crisis or storm
0.527 0.473 0.000
E05.4 Thyrotoxicosis factitia
0.527 0.473 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.527 0.473 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.527 0.473 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.527 0.473 0.000
L90 Atrophic disorders of skin
0.526 0.474 0.000
A07 Other protozoal intestinal diseases
0.526 0.474 0.000
A06 Amoebiasis
0.526 0.474 0.000
A05 Other bacterial foodborne intoxications
0.526 0.474 0.000
A03 Shigellosis
0.526 0.474 0.000
A02 Other Salmonella infections
0.526 0.474 0.000
A01 Typhoid and paratyphoid fevers
0.526 0.474 0.000
A00 Cholera
0.526 0.474 0.000
K29.5 Chronic gastritis, unspecified
0.526 0.474 0.000
S59 Other and unspecified injuries of forearm
0.525 0.475 0.000
S58 Traumatic amputation of forearm
0.525 0.475 0.000
S57 Crushing injury of forearm
0.525 0.475 0.000
S56 Injury of muscle and tendon at forearm level
0.525 0.475 0.000
S55 Injury of blood vessels at forearm level
0.525 0.475 0.000
S54 Injury of nerves at forearm level
0.525 0.475 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.525 0.475 0.000
S51 Open wound of forearm
0.525 0.475 0.000
S50 Superficial injury of forearm
0.525 0.475 0.000
K11 Diseases of salivary glands
0.524 0.475 0.000
K10 Other diseases of jaws
0.524 0.475 0.000
K09 Cysts of oral region, not elsewhere classified
0.524 0.475 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.524 0.475 0.000
K03 Other diseases of hard tissues of teeth
0.524 0.475 0.000
K00 Disorders of tooth development and eruption
0.524 0.475 0.000
H02 Other disorders of eyelid
0.523 0.476 0.000
S09 Other and unspecified injuries of head
0.523 0.476 0.000
T32 Corrosions classified according to extent of body surface involved
0.523 0.476 0.000
T30 Burn and corrosion, body region unspecified
0.523 0.476 0.000
T29 Burns and corrosions of multiple body regions
0.523 0.476 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.523 0.477 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.523 0.477 0.000
S32 Fracture of lumbar spine and pelvis
0.522 0.478 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.522 0.478 0.000
K14 Diseases of tongue
0.522 0.478 0.000
I50 Heart failure
0.522 0.478 0.000
I52 Other heart disorders in diseases classified elsewhere
0.521 0.479 0.000
I48 Atrial fibrillation and flutter
0.521 0.479 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.521 0.479 0.000
I41 Myocarditis in diseases classified elsewhere
0.521 0.479 0.000
I40 Acute myocarditis
0.521 0.479 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.521 0.479 0.000
I37 Pulmonary valve disorders
0.521 0.479 0.000
I36 Nonrheumatic tricuspid valve disorders
0.521 0.479 0.000
I33 Acute and subacute endocarditis
0.521 0.479 0.000
I32 Pericarditis in diseases classified elsewhere
0.521 0.479 0.000
I30 Acute pericarditis
0.521 0.479 0.000
K05 Gingivitis and periodontal diseases
0.521 0.479 0.000
E11 Non-insulin-dependent diabetes mellitus
0.521 0.479 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.520 0.480 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.520 0.480 0.000
I69 Sequelae of cerebrovascular disease
0.520 0.480 0.000
Chapter VI Diseases of the nervous system
0.520 0.480 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.519 0.480 0.000
I42 Cardiomyopathy
0.519 0.481 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.518 0.481 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.518 0.481 0.000
F02 Dementia in other diseases classified elsewhere
0.518 0.481 0.000
F01 Vascular dementia
0.518 0.481 0.000
F00 Dementia in Alzheimer's disease
0.518 0.481 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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