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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs184522131
log Bayes Factor = 1.69043
Chromosome 9   position 90,177,521  (GRCh37) Explore rs184522131 on Ensembl!
Variant rs184522131 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.979 0.021 0.000
Chapter XI Diseases of the digestive system
0.976 0.024 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.975 0.025 0.000
M15-M19 Arthrosis
0.962 0.038 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.945 0.055 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.940 0.060 0.000
K80 Cholelithiasis
0.916 0.084 0.000
M17 Gonarthrosis [arthrosis of knee]
0.910 0.090 0.000
K55-K64 Other diseases of intestines
0.894 0.106 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.891 0.109 0.000
M45-M49 Spondylopathies
0.862 0.138 0.000
M19 Other arthrosis
0.862 0.138 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.861 0.139 0.000
Chapter X Diseases of the respiratory system
0.845 0.155 0.000
Chapter VI Diseases of the nervous system
0.843 0.157 0.000
L40-L45 Papulosquamous disorders
0.835 0.165 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.834 0.166 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.831 0.169 0.000
M17.9 Gonarthrosis, unspecified
0.829 0.171 0.000
K20 Oesophagitis
0.826 0.174 0.000
M16 Coxarthrosis [arthrosis of hip]
0.822 0.178 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.815 0.185 0.000
M20-M25 Other joint disorders
0.806 0.194 0.000
M17.1 Other primary gonarthrosis
0.800 0.200 0.000
M05-M14 Inflammatory polyarthropathies
0.799 0.201 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.798 0.202 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.790 0.210 0.000
K30 Dyspepsia
0.789 0.211 0.000
D60-D64 Aplastic and other anaemias
0.783 0.217 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.776 0.224 0.000
K90-K93 Other diseases of the digestive system
0.774 0.226 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.773 0.227 0.000
M19.9 Arthrosis, unspecified
0.768 0.232 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.767 0.232 0.000
L40 Psoriasis
0.760 0.240 0.000
K60 Fissure and fistula of anal and rectal regions
0.760 0.240 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.758 0.242 0.000
Chapter VIII Diseases of the ear and mastoid process
0.755 0.245 0.000
M47 Spondylosis
0.749 0.251 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.744 0.256 0.000
Chapter VII Diseases of the eye and adnexa
0.743 0.257 0.000
K70-K77 Diseases of liver
0.742 0.258 0.000
K63 Other diseases of intestine
0.741 0.259 0.000
K62 Other diseases of anus and rectum
0.740 0.260 0.000
K83 Other diseases of biliary tract
0.739 0.261 0.000
M23 Internal derangement of knee
0.735 0.265 0.000
D64 Other anaemias
0.728 0.272 0.000
K22 Other diseases of oesophagus
0.720 0.280 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.718 0.282 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.717 0.282 0.000
K61 Abscess of anal and rectal regions
0.715 0.285 0.000
L40.9 Psoriasis, unspecified
0.707 0.293 0.000
M65-M68 Disorders of synovium and tendon
0.706 0.294 0.000
K82 Other diseases of gallbladder
0.704 0.296 0.000
L57.0 Actinic keratosis
0.704 0.296 0.000
K50-K52 Noninfective enteritis and colitis
0.704 0.296 0.000
Chapter XXII Codes for special purposes
0.702 0.298 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.702 0.298 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.702 0.298 0.000
L60-L75 Disorders of skin appendages
0.701 0.299 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.699 0.301 0.000
M91-M94 Chondropathies
0.699 0.301 0.000
M86-M90 Other osteopathies
0.699 0.301 0.000
M60-M63 Disorders of muscles
0.699 0.301 0.000
M40-M43 Deforming dorsopathies
0.699 0.301 0.000
M00-M03 Infectious arthropathies
0.699 0.301 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.697 0.303 0.000
J40-J47 Chronic lower respiratory diseases
0.693 0.307 0.000
M50-M54 Other dorsopathies
0.693 0.307 0.000
G40-G47 Episodic and paroxysmal disorders
0.691 0.309 0.000
M80-M85 Disorders of bone density and structure
0.691 0.309 0.000
M16.1 Other primary coxarthrosis
0.691 0.309 0.000
M18 Arthrosis of first carpometacarpal joint
0.689 0.310 0.000
M15 Polyarthrosis
0.689 0.310 0.000
D64.9 Anaemia, unspecified
0.688 0.312 0.000
M48 Other spondylopathies
0.686 0.314 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.683 0.317 0.000
J30-J39 Other diseases of upper respiratory tract
0.682 0.318 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.677 0.322 0.000
K86 Other diseases of pancreas
0.677 0.322 0.000
K85 Acute pancreatitis
0.677 0.322 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.675 0.325 0.000
M19.0 Primary arthrosis of other joints
0.675 0.325 0.000
J20-J22 Other acute lower respiratory infections
0.674 0.326 0.000
L50-L54 Urticaria and erythema
0.674 0.326 0.000
L10-L14 Bullous disorders
0.674 0.326 0.000
K25 Gastric ulcer
0.673 0.327 0.000
K62.8 Other specified diseases of anus and rectum
0.671 0.329 0.000
K35-K38 Diseases of appendix
0.670 0.330 0.000
R06 Abnormalities of breathing
0.669 0.331 0.000
J00-J06 Acute upper respiratory infections
0.666 0.334 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.665 0.335 0.000
K60.3 Anal fistula
0.665 0.335 0.000
K65-K67 Diseases of peritoneum
0.663 0.337 0.000
Chapter XX External causes of morbidity and mortality
0.663 0.337 0.000
K81 Cholecystitis
0.659 0.341 0.000
Chapter II Neoplasms
0.658 0.342 0.000
K80.3 Calculus of bile duct with cholangitis
0.656 0.343 0.000
K80.8 Other cholelithiasis
0.656 0.343 0.000
K80.4 Calculus of bile duct with cholecystitis
0.656 0.343 0.000
M17.5 Other secondary gonarthrosis
0.652 0.348 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.652 0.348 0.000
M17.3 Other posttraumatic gonarthrosis
0.652 0.348 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.652 0.348 0.000
M06 Other rheumatoid arthritis
0.650 0.350 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.648 0.352 0.000
E65-E68 Obesity and other hyperalimentation
0.646 0.354 0.000
M16.9 Coxarthrosis, unspecified
0.645 0.355 0.000
L20-L30 Dermatitis and eczema
0.645 0.355 0.000
K57 Diverticular disease of intestine
0.641 0.359 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.641 0.359 0.000
K55 Vascular disorders of intestine
0.641 0.359 0.000
Chapter V Mental and behavioural disorders
0.641 0.359 0.000
R42 Dizziness and giddiness
0.640 0.359 0.000
K28 Gastrojejunal ulcer
0.639 0.361 0.000
K27 Peptic ulcer, site unspecified
0.639 0.361 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.639 0.361 0.000
M70-M79 Other soft tissue disorders
0.638 0.362 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.636 0.363 0.000
M17.0 Primary gonarthrosis, bilateral
0.635 0.365 0.000
K63.5 Polyp of colon
0.634 0.366 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.632 0.368 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.632 0.368 0.000
M47.8 Other spondylosis
0.629 0.371 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.628 0.372 0.000
Chapter IX Diseases of the circulatory system
0.626 0.374 0.000
D50-D53 Nutritional anaemias
0.625 0.375 0.000
K40-K46 Hernia
0.624 0.376 0.000
K92 Other diseases of digestive system
0.623 0.377 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.621 0.378 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.621 0.379 0.000
L82 Seborrhoeic keratosis
0.619 0.381 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.618 0.382 0.000
M49 Spondylopathies in diseases classified elsewhere
0.618 0.382 0.000
M46 Other inflammatory spondylopathies
0.618 0.382 0.000
M45 Ankylosing spondylitis
0.618 0.382 0.000
M19.8 Other specified arthrosis
0.618 0.382 0.000
M19.2 Other secondary arthrosis
0.618 0.382 0.000
M19.1 Posttraumatic arthrosis of other joints
0.618 0.382 0.000
D80-D89 Certain disorders involving the immune mechanism
0.617 0.383 0.000
D55-D59 Haemolytic anaemias
0.617 0.383 0.000
S00-S09 Injuries to the head
0.616 0.384 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.615 0.385 0.000
K58 Irritable bowel syndrome
0.615 0.385 0.000
M19.94 Arthrosis, unspecified (Hand)
0.612 0.388 0.000
E70-E90 Metabolic disorders
0.611 0.389 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.608 0.392 0.000
M47.9 Spondylosis, unspecified
0.608 0.392 0.000
R00 Abnormalities of heart beat
0.608 0.392 0.000
K29 Gastritis and duodenitis
0.607 0.393 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.606 0.394 0.000
J60-J70 Lung diseases due to external agents
0.606 0.394 0.000
L90 Atrophic disorders of skin
0.605 0.395 0.000
G90-G99 Other disorders of the nervous system
0.605 0.395 0.000
G70-G73 Diseases of myoneural junction and muscle
0.605 0.395 0.000
G30-G32 Other degenerative diseases of the nervous system
0.605 0.395 0.000
G20-G26 Extrapyramidal and movement disorders
0.605 0.395 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.605 0.395 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.605 0.395 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.604 0.396 0.000
M25 Other joint disorders, not elsewhere classified
0.604 0.396 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.603 0.397 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.603 0.397 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.601 0.399 0.000
H30-H36 Disorders of choroid and retina
0.600 0.399 0.000
J45 Asthma
0.600 0.400 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.599 0.401 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.599 0.401 0.000
L44 Other papulosquamous disorders
0.599 0.401 0.000
L43 Lichen planus
0.599 0.401 0.000
L41 Parapsoriasis
0.599 0.401 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.599 0.401 0.000
L42 Pityriasis rosea
0.599 0.401 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.598 0.402 0.000
L58 Radiodermatitis
0.598 0.402 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.598 0.402 0.000
L55 Sunburn
0.598 0.402 0.000
H65-H75 Diseases of middle ear and mastoid
0.598 0.402 0.000
R04 Haemorrhage from respiratory passages
0.596 0.404 0.000
M10 Gout
0.595 0.405 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.595 0.405 0.000
G47 Sleep disorders
0.594 0.406 0.000
R06.8 Other and unspecified abnormalities of breathing
0.594 0.406 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.592 0.408 0.000
K83.8 Other specified diseases of biliary tract
0.592 0.408 0.000
M16.7 Other secondary coxarthrosis
0.589 0.410 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.589 0.410 0.000
M16.5 Other posttraumatic coxarthrosis
0.589 0.410 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.589 0.410 0.000
M16.3 Other dysplastic coxarthrosis
0.589 0.410 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.589 0.410 0.000
M16.0 Primary coxarthrosis, bilateral
0.589 0.410 0.000
K22.1 Ulcer of oesophagus
0.587 0.413 0.000
K61.0 Anal abscess
0.587 0.413 0.000
M13 Other arthritis
0.587 0.413 0.000
Chapter I Certain infectious and parasitic diseases
0.586 0.413 0.000
K31 Other diseases of stomach and duodenum
0.586 0.414 0.000
H25-H28 Disorders of lens
0.581 0.418 0.000
J95-J99 Other diseases of the respiratory system
0.579 0.421 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.578 0.422 0.000
M35 Other systemic involvement of connective tissue
0.578 0.422 0.000
M34 Systemic sclerosis
0.578 0.422 0.000
M33 Dermatopolymyositis
0.578 0.422 0.000
M32 Systemic lupus erythematosus
0.578 0.422 0.000
M31 Other necrotising vasculopathies
0.578 0.422 0.000
M30 Polyarteritis nodosa and related conditions
0.578 0.422 0.000
M24 Other specific joint derangements
0.578 0.422 0.000
M22 Disorders of patella
0.578 0.422 0.000
M21 Other acquired deformities of limbs
0.578 0.422 0.000
S80-S89 Injuries to the knee and lower leg
0.576 0.424 0.000
K76 Other diseases of liver
0.575 0.425 0.000
K26 Duodenal ulcer
0.574 0.426 0.000
M14 Arthropathies in other diseases classified elsewhere
0.573 0.427 0.000
M12 Other specific arthropathies
0.573 0.427 0.000
M11 Other crystal arthropathies
0.573 0.427 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.573 0.427 0.000
M08 Juvenile arthritis
0.573 0.427 0.000
M07 Psoriatic and enteropathic arthropathies
0.573 0.427 0.000
M05 Seropositive rheumatoid arthritis
0.573 0.427 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.572 0.428 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.572 0.428 0.000
L94 Other localised connective tissue disorders
0.572 0.428 0.000
L93 Lupus erythematosus
0.572 0.428 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.572 0.428 0.000
L91 Hypertrophic disorders of skin
0.572 0.428 0.000
L89 Decubitus ulcer
0.572 0.428 0.000
L87 Transepidermal elimination disorders
0.572 0.428 0.000
L85 Other epidermal thickening
0.572 0.428 0.000
L81 Other disorders of pigmentation
0.572 0.428 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.572 0.428 0.000
L88 Pyoderma gangrenosum
0.572 0.428 0.000
L86 Keratoderma in diseases classified elsewhere
0.572 0.428 0.000
L84 Corns and callosities
0.572 0.428 0.000
L83 Acanthosis nigricans
0.572 0.428 0.000
L80 Vitiligo
0.572 0.428 0.000
K62.1 Rectal polyp
0.569 0.431 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.566 0.434 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.566 0.434 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.566 0.434 0.000
R47-R49 Symptoms and signs involving speech and voice
0.566 0.434 0.000
R06.5 Mouth breathing
0.565 0.435 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.563 0.437 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.562 0.438 0.000
D61 Other aplastic anaemias
0.562 0.438 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.562 0.438 0.000
D62 Acute posthaemorrhagic anaemia
0.562 0.438 0.000
M48.0 Spinal stenosis
0.560 0.440 0.000
K92.0 Haematemesis
0.559 0.441 0.000
E50-E64 Other nutritional deficiencies
0.556 0.444 0.000
E40-E46 Malnutrition
0.556 0.444 0.000
E20-E35 Disorders of other endocrine glands
0.556 0.444 0.000
K63.9 Disease of intestine, unspecified
0.555 0.444 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.555 0.445 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.554 0.446 0.000
O85-O92 Complications predominantly related to the puerperium
0.554 0.446 0.000
O00-O08 Pregnancy with abortive outcome
0.554 0.446 0.000
S40-S49 Injuries to the shoulder and upper arm
0.554 0.446 0.000
E66 Obesity
0.553 0.447 0.000
K02 Dental caries
0.552 0.447 0.000
J22 Unspecified acute lower respiratory infection
0.552 0.447 0.000
S60-S69 Injuries to the wrist and hand
0.552 0.448 0.000
M19.98 Arthrosis, unspecified (Other)
0.551 0.449 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.551 0.449 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.551 0.449 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.551 0.449 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.551 0.449 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.551 0.449 0.000
R30-R39 Symptoms and signs involving the urinary system
0.550 0.450 0.000
O60-O75 Complications of labour and delivery
0.549 0.451 0.000
G56 Mononeuropathies of upper limb
0.549 0.451 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.547 0.453 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.546 0.454 0.000
L40.8 Other psoriasis
0.545 0.455 0.000
L40.5 Arthropathic psoriasis
0.545 0.455 0.000
L40.4 Guttate psoriasis
0.545 0.455 0.000
L40.3 Pustulosis palmaris et plantaris
0.545 0.455 0.000
L40.2 Acrodermatitis continua
0.545 0.455 0.000
L40.1 Generalised pustular psoriasis
0.545 0.455 0.000
L40.0 Psoriasis vulgaris
0.545 0.455 0.000
K60.5 Anorectal fistula
0.545 0.455 0.000
K60.4 Rectal fistula
0.545 0.455 0.000
K60.1 Chronic anal fissure
0.545 0.455 0.000
K60.0 Acute anal fissure
0.545 0.455 0.000
K50 Crohn's disease [regional enteritis]
0.545 0.455 0.000
J32 Chronic sinusitis
0.544 0.455 0.000
S01 Open wound of head
0.544 0.456 0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.544 0.456 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.544 0.456 0.000
L57.5 Actinic granuloma
0.544 0.456 0.000
L57.4 Cutis laxa senilis
0.544 0.456 0.000
L57.3 Poikiloderma of Civatte
0.544 0.456 0.000
L57.2 Cutis rhomboidalis nuchae
0.544 0.456 0.000
L57.1 Actinic reticuloid
0.544 0.456 0.000
M06.9 Rheumatoid arthritis, unspecified
0.544 0.456 0.000
J09-J18 Influenza and pneumonia
0.543 0.457 0.000
K60.2 Anal fissure, unspecified
0.543 0.457 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.541 0.458 0.000
H80-H83 Diseases of inner ear
0.541 0.459 0.000
H60-H62 Diseases of external ear
0.541 0.459 0.000
J40 Bronchitis, not specified as acute or chronic
0.538 0.462 0.000
O80-O84 Delivery
0.537 0.462 0.000
M47.2 Other spondylosis with radiculopathy
0.537 0.463 0.000
M47.1 Other spondylosis with myelopathy
0.537 0.463 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.537 0.463 0.000
H90-H95 Other disorders of ear
0.537 0.463 0.000
J45.9 Asthma, unspecified
0.534 0.466 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.533 0.467 0.000
T79-T79 Certain early complications of trauma
0.533 0.467 0.000
T66-T78 Other and unspecified effects of external causes
0.533 0.467 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.533 0.467 0.000
T33-T35 Frostbite
0.533 0.467 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.533 0.467 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.533 0.467 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.533 0.467 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.533 0.467 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.533 0.467 0.000
T00-T07 Injuries involving multiple body regions
0.533 0.467 0.000
S90-S99 Injuries to the ankle and foot
0.533 0.467 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.533 0.467 0.000
S20-S29 Injuries to the thorax
0.533 0.467 0.000
S10-S19 Injuries to the neck
0.533 0.467 0.000
H55-H59 Other disorders of eye and adnexa
0.533 0.467 0.000
H53-H54 Visual disturbances and blindness
0.533 0.467 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.533 0.467 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.533 0.467 0.000
H43-H45 Disorders of vitreous body and globe
0.533 0.467 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.533 0.467 0.000
H10-H13 Disorders of conjunctiva
0.533 0.467 0.000
K22.7 Barrett's oesophagus
0.532 0.468 0.000
K01 Embedded and impacted teeth
0.532 0.468 0.000
K77 Liver disorders in diseases classified elsewhere
0.532 0.468 0.000
K75 Other inflammatory liver diseases
0.532 0.468 0.000
K74 Fibrosis and cirrhosis of liver
0.532 0.468 0.000
K73 Chronic hepatitis, not elsewhere classified
0.532 0.468 0.000
K72 Hepatic failure, not elsewhere classified
0.532 0.468 0.000
K71 Toxic liver disease
0.532 0.468 0.000
K70 Alcoholic liver disease
0.532 0.468 0.000
K82.8 Other specified diseases of gallbladder
0.532 0.468 0.000
K63.4 Enteroptosis
0.531 0.468 0.000
K63.3 Ulcer of intestine
0.531 0.468 0.000
K63.2 Fistula of intestine
0.531 0.468 0.000
K63.1 Perforation of intestine (nontraumatic)
0.531 0.468 0.000
K63.0 Abscess of intestine
0.531 0.468 0.000
K51 Ulcerative colitis
0.531 0.469 0.000
K62.9 Disease of anus and rectum, unspecified
0.531 0.469 0.000
K62.7 Radiation proctitis
0.531 0.469 0.000
K62.6 Ulcer of anus and rectum
0.531 0.469 0.000
K62.4 Stenosis of anus and rectum
0.531 0.469 0.000
K62.3 Rectal prolapse
0.531 0.469 0.000
K62.2 Anal prolapse
0.531 0.469 0.000
K62.0 Anal polyp
0.531 0.469 0.000
K83.9 Disease of biliary tract, unspecified
0.530 0.470 0.000
K83.5 Biliary cyst
0.530 0.470 0.000
K83.4 Spasm of sphincter of Oddi
0.530 0.470 0.000
K83.3 Fistula of bile duct
0.530 0.470 0.000
K83.2 Perforation of bile duct
0.530 0.470 0.000
K83.1 Obstruction of bile duct
0.530 0.470 0.000
K83.0 Cholangitis
0.530 0.470 0.000
L60 Nail disorders
0.530 0.470 0.000
J03 Acute tonsillitis
0.528 0.472 0.000
M23.9 Internal derangement of knee, unspecified
0.527 0.473 0.000
M23.8 Other internal derangements of knee
0.527 0.473 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.527 0.473 0.000
M23.5 Chronic instability of knee
0.527 0.473 0.000
M23.4 Loose body in knee
0.527 0.473 0.000
M23.3 Other meniscus derangements
0.527 0.473 0.000
M23.1 Discoid meniscus (congenital)
0.527 0.473 0.000
M23.0 Cystic meniscus
0.527 0.473 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.526 0.474 0.000
D69 Purpura and other haemorrhagic conditions
0.525 0.474 0.000
J47 Bronchiectasis
0.525 0.474 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.525 0.475 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.525 0.475 0.000
D64.8 Other specified anaemias
0.522 0.478 0.000
D64.4 Congenital dyserythropoietic anaemia
0.522 0.478 0.000
D64.3 Other sideroblastic anaemias
0.522 0.478 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.522 0.478 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.522 0.478 0.000
D64.0 Hereditary sideroblastic anaemia
0.522 0.478 0.000
M47.82 Other spondylosis (Cervical region)
0.522 0.478 0.000
S70-S79 Injuries to the hip and thigh
0.521 0.479 0.000
K59 Other functional intestinal disorders
0.520 0.479 0.000
M54 Dorsalgia
0.520 0.480 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.519 0.481 0.000
R00.1 Bradycardia, unspecified
0.519 0.481 0.000
J90-J94 Other diseases of pleura
0.517 0.482 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.517 0.482 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.517 0.483 0.000
K22.9 Disease of oesophagus, unspecified
0.516 0.483 0.000
K22.8 Other specified diseases of oesophagus
0.516 0.483 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.516 0.483 0.000
K22.5 Diverticulum of oesophagus, acquired
0.516 0.483 0.000
K22.4 Dyskinesia of oesophagus
0.516 0.483 0.000
K22.3 Perforation of oesophagus
0.516 0.483 0.000
K22.2 Oesophageal obstruction
0.516 0.483 0.000
K22.0 Achalasia of cardia
0.516 0.483 0.000
K40 Inguinal hernia
0.516 0.484 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.515 0.485 0.000
R01 Cardiac murmurs and other cardiac sounds
0.515 0.485 0.000
R02 Gangrene, not elsewhere classified
0.515 0.485 0.000
G47.3 Sleep apnoea
0.515 0.485 0.000
K14 Diseases of tongue
0.514 0.485 0.000
K12 Stomatitis and related lesions
0.514 0.485 0.000
K11 Diseases of salivary glands
0.514 0.485 0.000
K10 Other diseases of jaws
0.514 0.485 0.000
K09 Cysts of oral region, not elsewhere classified
0.514 0.485 0.000
K07 Dentofacial anomalies [including malocclusion]
0.514 0.485 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.514 0.485 0.000
K05 Gingivitis and periodontal diseases
0.514 0.485 0.000
K04 Diseases of pulp and periapical tissues
0.514 0.485 0.000
K03 Other diseases of hard tissues of teeth
0.514 0.485 0.000
K00 Disorders of tooth development and eruption
0.514 0.485 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.514 0.486 0.000
M65 Synovitis and tenosynovitis
0.513 0.487 0.000
K61.4 Intrasphincteric abscess
0.513 0.487 0.000
K61.3 Ischiorectal abscess
0.513 0.487 0.000
K61.2 Anorectal abscess
0.513 0.487 0.000
K61.1 Rectal abscess
0.513 0.487 0.000
E86 Volume depletion
0.510 0.490 0.000
J33 Nasal polyp
0.510 0.490 0.000
E00-E07 Disorders of thyroid gland
0.510 0.490 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.509 0.491 0.000
R06.0 Dyspnoea
0.509 0.491 0.000
K08 Other disorders of teeth and supporting structures
0.508 0.492 0.000
K91.4 Colostomy and enterostomy malfunction
0.507 0.493 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.506 0.494 0.000
M67 Other disorders of synovium and tendon
0.506 0.494 0.000
M66 Spontaneous rupture of synovium and tendon
0.506 0.494 0.000
K82.9 Disease of gallbladder, unspecified
0.505 0.495 0.000
K82.4 Cholesterolosis of gallbladder
0.505 0.495 0.000
K82.3 Fistula of gallbladder
0.505 0.495 0.000
K82.2 Perforation of gallbladder
0.505 0.495 0.000
K82.1 Hydrops of gallbladder
0.505 0.495 0.000
K82.0 Obstruction of gallbladder
0.505 0.495 0.000
P90-P96 Other disorders originating in the perinatal period
0.503 0.497 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.503 0.497 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.503 0.497 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.503 0.497 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.503 0.497 0.000
P35-P39 Infections specific to the perinatal period
0.503 0.497 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.503 0.497 0.000
P10-P15 Birth trauma
0.503 0.497 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.503 0.497 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.503 0.497 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.503 0.497 0.000
Q80-Q89 Other congenital malformations
0.503 0.497 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.503 0.497 0.000
Q60-Q64 Congenital malformations of the urinary system
0.503 0.497 0.000
Q50-Q56 Congenital malformations of genital organs
0.503 0.497 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.503 0.497 0.000
Q35-Q37 Cleft lip and cleft palate
0.503 0.497 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.503 0.497 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.503 0.497 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.503 0.497 0.000
Q00-Q07 Congenital malformations of the nervous system
0.503 0.497 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.503 0.497 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.503 0.497 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.503 0.497 0.000
L75 Apocrine sweat disorders
0.503 0.497 0.000
L74 Eccrine sweat disorders
0.503 0.497 0.000
L73 Other follicular disorders
0.503 0.497 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.503 0.497 0.000
L71 Rosacea
0.503 0.497 0.000
L70 Acne
0.503 0.497 0.000
L68 Hypertrichosis
0.503 0.497 0.000
L67 Hair colour and hair shaft abnormalities
0.503 0.497 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.503 0.497 0.000
L65 Other nonscarring hair loss
0.503 0.497 0.000
L64 Androgenic alopecia
0.503 0.497 0.000
L63 Alopecia areata
0.503 0.497 0.000
L62 Nail disorders in diseases classified elsewhere
0.503 0.497 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.502 0.498 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.501 0.498 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.501 0.499 0.000
M02 Reactive arthropathies
0.501 0.499 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.501 0.499 0.000
M00 Pyogenic arthritis
0.501 0.499 0.000
M43 Other deforming dorsopathies
0.501 0.499 0.000
M42 Spinal osteochondrosis
0.501 0.499 0.000
M41 Scoliosis
0.501 0.499 0.000
M40 Kyphosis and lordosis
0.501 0.499 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.501 0.499 0.000
M62 Other disorders of muscle
0.501 0.499 0.000
M61 Calcification and ossification of muscle
0.501 0.499 0.000
M60 Myositis
0.501 0.499 0.000
M90 Osteopathies in diseases classified elsewhere
0.501 0.499 0.000
M89 Other disorders of bone
0.501 0.499 0.000
M88 Paget's disease of bone [osteitis deformans]
0.501 0.499 0.000
M87 Osteonecrosis
0.501 0.499 0.000
M86 Osteomyelitis
0.501 0.499 0.000
M94 Other disorders of cartilage
0.501 0.499 0.000
M93 Other osteochondropathies
0.501 0.499 0.000
M92 Other juvenile osteochondrosis
0.501 0.499 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.501 0.499 0.000
M99 Biomechanical lesions, not elsewhere classified
0.501 0.499 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.501 0.499 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.501 0.499 0.000
H40-H42 Glaucoma
0.500 0.500 0.000
K29.5 Chronic gastritis, unspecified
0.500 0.500 0.000
R46 Symptoms and signs involving appearance and behaviour
0.500 0.500 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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