TreeWAS – Variant ID: rs1916333

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S02 Fracture of skull and facial bones	0.064	0.936	0.000
S06 Intracranial injury	0.062	0.938	0.000
S00-S09 Injuries to the head	0.062	0.938	0.000
S05 Injury of eye and orbit	0.061	0.939	0.000
S02.1 Fracture of base of skull	0.061	0.939	0.000
S02.10 Fracture of base of skull (closed)	0.060	0.940	0.000
S02.2 Fracture of nasal bones	0.059	0.941	0.000
S06.5 Traumatic subdural haemorrhage	0.058	0.942	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.056	0.944	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.055	0.945	0.000
S02.20 Fracture of nasal bones (closed)	0.055	0.945	0.000
S05.8 Other injuries of eye and orbit	0.055	0.945	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.947	0.053
S05.9 Injury of eye and orbit, part unspecified	0.053	0.947	0.000
S06.3 Focal brain injury	0.052	0.948	0.000
S02.8 Fractures of other skull and facial bones	0.051	0.949	0.000
S06.8 Other intracranial injuries	0.051	0.949	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.051	0.949	0.000
S06.2 Diffuse brain injury	0.050	0.950	0.000
S05.1 Contusion of eyeball and orbital tissues	0.050	0.950	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.050	0.950	0.000
S06.4 Epidural haemorrhage	0.048	0.951	0.000
S02.4 Fracture of malar and maxillary bones	0.048	0.952	0.000
S02.7 Multiple fractures involving skull and facial bones	0.048	0.952	0.000
S06.9 Intracranial injury, unspecified	0.047	0.952	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.047	0.953	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.047	0.953	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.047	0.953	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.045	0.955	0.000
S02.6 Fracture of mandible	0.045	0.955	0.000
S06.7 Intracranial injury with prolonged coma	0.045	0.955	0.000
S02.21 Fracture of nasal bones (open)	0.045	0.955	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.044	0.955	0.000
S07 Crushing injury of head	0.044	0.956	0.000
S05.7 Avulsion of eye	0.044	0.956	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.044	0.956	0.000
S06.1 Traumatic cerebral oedema	0.044	0.956	0.000
S08 Traumatic amputation of part of head	0.044	0.956	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.044	0.956	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.043	0.957	0.000
S02.5 Fracture of tooth	0.043	0.957	0.000
S02.0 Fracture of vault of skull	0.042	0.958	0.000
S04 Injury of cranial nerves	0.042	0.958	0.000
S09 Other and unspecified injuries of head	0.042	0.958	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.042	0.958	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.042	0.958	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.041	0.959	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.041	0.959	0.000
S02.3 Fracture of orbital floor	0.041	0.959	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.040	0.959	0.000
S01.1 Open wound of eyelid and periocular area	0.040	0.960	0.000
S01 Open wound of head	0.040	0.960	0.000
S02.11 Fracture of base of skull (open)	0.040	0.960	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.039	0.961	0.000
S01.4 Open wound of cheek and temporomandibular area	0.039	0.961	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.038	0.962	0.000
S09.8 Other specified injuries of head	0.037	0.963	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.037	0.963	0.000
S02.81 Fractures of other skull and facial bones (open)	0.037	0.963	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.037	0.963	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.036	0.964	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.036	0.964	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.036	0.964	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.036	0.964	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.035	0.964	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.035	0.965	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.035	0.965	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.034	0.966	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.034	0.966	0.000
S06.0 Concussion	0.034	0.966	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.033	0.967	0.000
S02.61 Fracture of mandible (open)	0.032	0.968	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.032	0.968	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.032	0.968	0.000
S03.1 Dislocation of septal cartilage of nose	0.032	0.968	0.000
S03.0 Dislocation of jaw	0.032	0.968	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.032	0.968	0.000
S03.4 Sprain and strain of jaw	0.032	0.968	0.000
S03.3 Dislocation of other and unspecified parts of head	0.032	0.968	0.000
S03.2 Dislocation of tooth	0.032	0.968	0.000
S07.9 Crushing injury of head, part unspecified	0.032	0.968	0.000
S07.8 Crushing injury of other parts of head	0.032	0.968	0.000
S07.1 Crushing injury of skull	0.032	0.968	0.000
S07.0 Crushing injury of face	0.032	0.968	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.032	0.968	0.000
S08.9 Traumatic amputation of unspecified part of head	0.032	0.968	0.000
S08.8 Traumatic amputation of other parts of head	0.032	0.968	0.000
S08.0 Avulsion of scalp	0.032	0.968	0.000
S08.1 Traumatic amputation of ear	0.031	0.968	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.031	0.969	0.000
S02.51 Fracture of tooth (open)	0.031	0.969	0.000
S02.60 Fracture of mandible (closed)	0.031	0.969	0.000
S04.9 Injury of unspecified cranial nerve	0.030	0.969	0.000
S04.8 Injury of other cranial nerves	0.030	0.969	0.000
S04.7 Injury of accessory nerve	0.030	0.969	0.000
S04.6 Injury of acoustic nerve	0.030	0.969	0.000
S04.4 Injury of abducent nerve	0.030	0.969	0.000
S04.3 Injury of trigeminal nerve	0.030	0.969	0.000
S04.2 Injury of trochlear nerve	0.030	0.969	0.000
S04.1 Injury of oculomotor nerve	0.030	0.969	0.000
S04.0 Injury of optic nerve and pathways	0.030	0.969	0.000
S09.1 Injury of muscle and tendon of head	0.030	0.969	0.000
S02.01 Fracture of vault of skull (open)	0.030	0.970	0.000
S02.31 Fracture of orbital floor (open)	0.029	0.970	0.000
S09.2 Traumatic rupture of ear drum	0.028	0.971	0.000
S04.5 Injury of facial nerve	0.028	0.971	0.000
S02.50 Fracture of tooth (closed)	0.028	0.972	0.000
S02.00 Fracture of vault of skull (closed)	0.027	0.973	0.000
S09.7 Multiple injuries of head	0.026	0.974	0.000
S01.7 Multiple open wounds of head	0.026	0.974	0.000
S01.0 Open wound of scalp	0.026	0.974	0.000
S01.3 Open wound of ear	0.025	0.975	0.000
S06.01 Concussion (with open intracranial wound)	0.024	0.975	0.000
S02.30 Fracture of orbital floor (closed)	0.024	0.976	0.000
S01.5 Open wound of lip and oral cavity	0.019	0.981	0.000
S01.8 Open wound of other parts of head	0.018	0.982	0.000
S09.9 Unspecified injury of head	0.017	0.983	0.000
B02.9 Zoster without complication	0.017	0.983	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.000	0.986	0.014
T42.4 Benzodiazepines	0.014	0.986	0.000
Z93.3 Colostomy status	0.000	0.986	0.014
H04 Disorders of lachrymal system	0.000	0.986	0.014
S06.00 Concussion (without open intracranial wound)	0.013	0.986	0.001
S01.2 Open wound of nose	0.013	0.987	0.000
T93 Sequelae of injuries of lower limb	0.013	0.987	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.013	0.987	0.000
T93.2 Sequelae of other fractures of lower limb	0.013	0.987	0.000
H04.8 Other disorders of lachrymal system	0.000	0.988	0.012
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.012	0.988	0.000
T90 Sequelae of injuries of head	0.012	0.988	0.000
H04.4 Chronic inflammation of lachrymal passages	0.000	0.988	0.012
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.012	0.988	0.000
H04.9 Disorder of lachrymal system, unspecified	0.000	0.988	0.012
H04.1 Other disorders of lachrymal gland	0.000	0.988	0.012
T42.1 Iminostilbenes	0.011	0.988	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.011	0.989	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.011	0.989	0.000
H04.2 Epiphora	0.000	0.989	0.011
Z13.9 Special screening examination, unspecified	0.011	0.989	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.011	0.989	0.000
T95 Sequelae of burns, corrosions and frostbite	0.011	0.989	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.011	0.989	0.000
H04.0 Dacryoadenitis	0.000	0.989	0.011
H04.3 Acute and unspecified inflammation of lachrymal passages	0.000	0.989	0.011
H04.6 Other changes in lachrymal passages	0.000	0.989	0.010
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.010	0.990	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.010	0.990	0.000
T90.1 Sequelae of open wound of head	0.010	0.990	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.010	0.990	0.000
T90.4 Sequelae of injury of eye and orbit	0.010	0.990	0.000
T42.3 Barbiturates	0.010	0.990	0.000
T90.5 Sequelae of intracranial injury	0.010	0.990	0.000
T90.0 Sequelae of superficial injury of head	0.010	0.990	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.010	0.990	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.010	0.990	0.000
T91 Sequelae of injuries of neck and trunk	0.010	0.990	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.010	0.990	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.010	0.990	0.000
T42.2 Succinimides and oxazolidinediones	0.010	0.990	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.009	0.990	0.000
B02 Zoster [herpes zoster]	0.009	0.991	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.009	0.991	0.000
T98 Sequelae of other and unspecified effects of external causes	0.009	0.991	0.000
T90.8 Sequelae of other specified injuries of head	0.009	0.991	0.000
S10-S19 Injuries to the neck	0.009	0.991	0.000
T90.3 Sequelae of injury of cranial nerves	0.009	0.991	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.009	0.991	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.009	0.991	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.009	0.991	0.000
T93.1 Sequelae of fracture of femur	0.009	0.991	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.009	0.991	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.009	0.991	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.009	0.991	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.009	0.991	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.008	0.991	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.008	0.991	0.000
T93.0 Sequelae of open wound of lower limb	0.008	0.991	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.008	0.991	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.008	0.991	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.008	0.991	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.008	0.991	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.008	0.992	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.008	0.992	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.008	0.992	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.008	0.992	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.008	0.992	0.000
T66-T78 Other and unspecified effects of external causes	0.008	0.992	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.008	0.992	0.000
B02.2 Zoster with other nervous system involvement	0.008	0.992	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.008	0.992	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.008	0.992	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.008	0.992	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.008	0.992	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.008	0.992	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.008	0.992	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.008	0.992	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.008	0.992	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.008	0.992	0.000
T43.9 Psychotropic drug, unspecified	0.008	0.992	0.000
S19 Other and unspecified injuries of neck	0.008	0.992	0.000
T91.1 Sequelae of fracture of spine	0.008	0.992	0.000
T90.9 Sequelae of unspecified injury of head	0.008	0.992	0.000
S11 Open wound of neck	0.008	0.992	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.008	0.992	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.992	0.008
T20-T25 Burns and corrosions of external body surface, specified by site	0.008	0.992	0.000
S01.9 Open wound of head, part unspecified	0.006	0.992	0.002
T43.8 Other psychotropic drugs, not elsewhere classified	0.008	0.992	0.000
T43.2 Other and unspecified antidepressants	0.008	0.992	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.992	0.008
D47.4 Osteomyelofibrosis	0.000	0.992	0.008
T43.6 Psychostimulants with abuse potential	0.007	0.992	0.000
S19.9 Unspecified injury of neck	0.007	0.992	0.000
T40.5 Cocaine	0.007	0.992	0.000
D47.2 Monoclonal gammopathy	0.000	0.992	0.007
T23 Burn and corrosion of wrist and hand	0.007	0.992	0.000
T36 Poisoning by systemic antibiotics	0.007	0.993	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.007	0.993	0.000
T40.2 Other opioids	0.007	0.993	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.007	0.993	0.000
T45.5 Anticoagulants	0.007	0.993	0.000
B02.8 Zoster with other complications	0.007	0.993	0.000
B02.1 Zoster meningitis	0.007	0.993	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.007	0.993	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.007	0.993	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.007	0.993	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.007	0.993	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.007	0.993	0.000
T33-T35 Frostbite	0.007	0.993	0.000
T23.2 Burn of second degree of wrist and hand	0.007	0.993	0.000
T45.4 Iron and its compounds	0.007	0.993	0.000
T51 Toxic effect of alcohol	0.007	0.993	0.000
T51.0 Ethanol	0.007	0.993	0.000
S12 Fracture of neck	0.007	0.993	0.000
B02.7 Disseminated zoster	0.007	0.993	0.000
B02.0 Zoster encephalitis	0.007	0.993	0.000
T42.0 Hydantoin derivatives	0.007	0.993	0.000
T59 Toxic effect of other gases, fumes and vapours	0.007	0.993	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.007	0.993	0.000
T98.2 Sequelae of certain early complications of trauma	0.007	0.993	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.007	0.993	0.000
T56 Toxic effect of metals	0.007	0.993	0.000
S31 Open wound of abdomen, lower back and pelvis	0.007	0.993	0.000
T40.6 Other and unspecified narcotics	0.007	0.993	0.000
S14 Injury of nerves and spinal cord at neck level	0.007	0.993	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.007	0.993	0.000
S17 Crushing injury of neck	0.007	0.993	0.000
S15 Injury of blood vessels at neck level	0.007	0.993	0.000
S10 Superficial injury of neck	0.007	0.993	0.000
S18 Traumatic amputation at neck level	0.007	0.993	0.000
S16 Injury of muscle and tendon at neck level	0.007	0.993	0.000
T40.1 Heroin	0.007	0.993	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.007	0.993	0.000
T40.8 Lysergide [LSD]	0.007	0.993	0.000
T40.7 Cannabis (derivatives)	0.007	0.993	0.000
T40.0 Opium	0.007	0.993	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.007	0.993	0.000
T45.8 Other primarily systemic and haematological agents	0.007	0.993	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.007	0.993	0.000
T45.6 Fibrinolysis-affecting drugs	0.007	0.993	0.000
T45.3 Enzymes, not elsewhere classified	0.007	0.993	0.000
T45.2 Vitamins, not elsewhere classified	0.007	0.993	0.000
T65 Toxic effect of other and unspecified substances	0.007	0.993	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.007	0.993	0.000
T68 Hypothermia	0.007	0.993	0.000
T78 Adverse effects, not elsewhere classified	0.007	0.993	0.000
T40.3 Methadone	0.007	0.993	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.007	0.993	0.000
T00-T07 Injuries involving multiple body regions	0.007	0.993	0.000
S11.9 Open wound of neck, part unspecified	0.007	0.993	0.000
T55 Toxic effect of soaps and detergents	0.007	0.993	0.000
T75 Effects of other external causes	0.007	0.993	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.007	0.993	0.000
T54 Toxic effect of corrosive substances	0.007	0.993	0.000
T47.0 Histamine H(2)-receptor antagonists	0.006	0.993	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.006	0.993	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.006	0.993	0.000
T20 Burn and corrosion of head and neck	0.007	0.993	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.006	0.993	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.006	0.993	0.000
T46.7 Peripheral vasodilators	0.006	0.993	0.000
T48.5 Anti-common-cold drugs	0.006	0.993	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.006	0.993	0.000
T48.4 Expectorants	0.006	0.993	0.000
T48.3 Antitussives	0.006	0.993	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.006	0.993	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.006	0.993	0.000
T48.0 Oxytocic drugs	0.006	0.993	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.006	0.993	0.000
T41.2 Other and unspecified general anaesthetics	0.006	0.993	0.000
T38.0 Glucocorticoids and synthetic analogues	0.006	0.993	0.000
T45.0 Antiallergic and antiemetic drugs	0.006	0.994	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.006	0.994	0.000
T47.6 Antidiarrhoeal drugs	0.006	0.994	0.000
T38.5 Other oestrogens and progestogens	0.006	0.994	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.006	0.994	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.006	0.994	0.000
T41.5 Therapeutic gases	0.006	0.994	0.000
T41.4 Anaesthetic, unspecified	0.006	0.994	0.000
T41.3 Local anaesthetics	0.006	0.994	0.000
T41.1 Intravenous anaesthetics	0.006	0.994	0.000
T41.0 Inhaled anaesthetics	0.006	0.994	0.000
T78.3 Angioneurotic oedema	0.006	0.994	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.006	0.994	0.000
S70-S79 Injuries to the hip and thigh	0.006	0.994	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.006	0.994	0.000
T70 Effects of air pressure and water pressure	0.006	0.994	0.000
N48.6 Balanitis xerotica obliterans	0.000	0.994	0.006
T38.9 Other and unspecified hormone antagonists	0.006	0.994	0.000
T38.7 Androgens and anabolic congeners	0.006	0.994	0.000
T38.4 Oral contraceptives	0.006	0.994	0.000
T38.2 Antithyroid drugs	0.006	0.994	0.000
T60 Toxic effect of pesticides	0.006	0.994	0.000
T57 Toxic effect of other inorganic substances	0.006	0.994	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.006	0.994	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.006	0.994	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.006	0.994	0.000
T37.5 Antiviral drugs	0.006	0.994	0.000
T37.4 Anthelminthics	0.006	0.994	0.000
T37.3 Other antiprotozoal drugs	0.006	0.994	0.000
T37.1 Antimycobacterial drugs	0.006	0.994	0.000
T37.0 Sulphonamides	0.006	0.994	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.006	0.994	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.006	0.994	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.994	0.006
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.006	0.994	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.994	0.006
T50.8 Diagnostic agents	0.006	0.994	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.006	0.994	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.006	0.994	0.000
T47.7 Emetics	0.006	0.994	0.000
T47.5 Digestants	0.006	0.994	0.000
T47.3 Saline and osmotic laxatives	0.006	0.994	0.000
T50.4 Drugs affecting uric acid metabolism	0.006	0.994	0.000
T71 Asphyxiation	0.006	0.994	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.006	0.994	0.000
T74 Maltreatment syndromes	0.006	0.994	0.000
T69 Other effects of reduced temperature	0.006	0.994	0.000
T67 Effects of heat and light	0.006	0.994	0.000
T52 Toxic effect of organic solvents	0.006	0.994	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.006	0.994	0.000
S31.1 Open wound of abdominal wall	0.006	0.994	0.000
S13.4 Sprain and strain of cervical spine	0.006	0.994	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
T50.7 Analeptics and opioid receptor antagonists	0.006	0.994	0.000
T50.5 Appetite depressants	0.006	0.994	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.006	0.994	0.000
T50.0 Mineralocorticoids and their antagonists	0.006	0.994	0.000
T73 Effects of other deprivation	0.006	0.994	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.006	0.994	0.000
T91.3 Sequelae of injury of spinal cord	0.006	0.994	0.000
S11.8 Open wound of other parts of neck	0.006	0.994	0.000
T79-T79 Certain early complications of trauma	0.006	0.994	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.006	0.994	0.000
T49.9 Topical agent, unspecified	0.006	0.994	0.000
T49.8 Other topical agents	0.006	0.994	0.000
T49.7 Dental drugs, topically applied	0.006	0.994	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.006	0.994	0.000
T49.5 Ophthalmological drugs and preparations	0.006	0.994	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.006	0.994	0.000
T49.3 Emollients, demulcents and protectants	0.006	0.994	0.000
T49.2 Local astringents and local detergents	0.006	0.994	0.000
T49.1 Antipruritics	0.006	0.994	0.000
T62 Toxic effect of other noxious substances eaten as food	0.006	0.994	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.006	0.994	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.006	0.994	0.000
T50.1 Loop [high-ceiling] diuretics	0.006	0.994	0.000
T59.8 Other specified gases, fumes and vapours	0.006	0.994	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.006	0.994	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.006	0.994	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.006	0.994	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.006	0.994	0.000
T44.0 Anticholinesterase agents	0.006	0.994	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.006	0.994	0.000
S11.7 Multiple open wounds of neck	0.006	0.994	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.006	0.994	0.000
S19.7 Multiple injuries of neck	0.006	0.994	0.000
T66 Unspecified effects of radiation	0.006	0.994	0.000
S31.0 Open wound of lower back and pelvis	0.006	0.994	0.000
T23.1 Burn of first degree of wrist and hand	0.006	0.994	0.000
S11.2 Open wound involving pharynx and cervical oesophagus	0.006	0.994	0.000
S11.1 Open wound involving thyroid gland	0.006	0.994	0.000
S11.0 Open wound involving larynx and trachea	0.006	0.994	0.000
T47.2 Stimulant laxatives	0.006	0.994	0.000
T38.1 Thyroid hormones and substitutes	0.006	0.994	0.000
T47.4 Other laxatives	0.006	0.994	0.000
S12.2 Fracture of other specified cervical vertebra	0.006	0.994	0.000
T63 Toxic effect of contact with venomous animals	0.006	0.994	0.000
T40.4 Other synthetic narcotics	0.006	0.994	0.000
T56.8 Other metals	0.006	0.994	0.000
T26 Burn and corrosion confined to eye and adnexa	0.006	0.994	0.000
T36.4 Tetracyclines	0.006	0.994	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.994	0.006
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.006	0.994	0.000
B02.3 Zoster ocular disease	0.006	0.994	0.000
T20.0 Burn of unspecified degree of head and neck	0.006	0.994	0.000
T36.8 Other systemic antibiotics	0.005	0.994	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.005	0.994	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.994	0.000
T94.1 Sequelae of injuries, not specified by body region	0.005	0.994	0.000
S00 Superficial injury of head	0.006	0.994	0.000
T23.7 Corrosion of third degree of wrist and hand	0.005	0.994	0.000
T23.6 Corrosion of second degree of wrist and hand	0.005	0.994	0.000
T23.5 Corrosion of first degree of wrist and hand	0.005	0.994	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.005	0.994	0.000
T36.9 Systemic antibiotic, unspecified	0.005	0.994	0.000
T36.7 Antifungal antibiotics, systemically used	0.005	0.994	0.000
T36.6 Rifamycins	0.005	0.994	0.000
T36.5 Aminoglycosides	0.005	0.994	0.000
T36.2 Chloramphenicol group	0.005	0.994	0.000
S37 Injury of urinary and pelvic organs	0.005	0.994	0.000
T28 Burn and corrosion of other internal organs	0.005	0.994	0.000
T27 Burn and corrosion of respiratory tract	0.005	0.994	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.994	0.005
S10.1 Other and unspecified superficial injuries of throat	0.005	0.994	0.000
T65.9 Toxic effect of unspecified substance	0.005	0.994	0.000
T46.1 Calcium-channel blockers	0.005	0.994	0.000
S36 Injury of intra-abdominal organs	0.005	0.994	0.000
T36.3 Macrolides	0.005	0.995	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.005	0.995	0.000
S79 Other and unspecified injuries of hip and thigh	0.005	0.995	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.005	0.995	0.000
T34 Frostbite with tissue necrosis	0.005	0.995	0.000
T33 Superficial frostbite	0.005	0.995	0.000
S12.9 Fracture of neck, part unspecified	0.005	0.995	0.000
S50 Superficial injury of forearm	0.005	0.995	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.995	0.005
S31.2 Open wound of penis	0.005	0.995	0.000
T75.1 Drowning and nonfatal submersion	0.005	0.995	0.000
T25 Burn and corrosion of ankle and foot	0.005	0.995	0.000
T02 Fractures involving multiple body regions	0.005	0.995	0.000
T58 Toxic effect of carbon monoxide	0.005	0.995	0.000
T51.8 Other alcohols	0.005	0.995	0.000
T51.3 Fusel oil	0.005	0.995	0.000
T51.2 2-Propanol	0.005	0.995	0.000
T51.1 Methanol	0.005	0.995	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.995	0.000
S12.8 Fracture of other parts of neck	0.005	0.995	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.005	0.995	0.000
S14.3 Injury of brachial plexus	0.005	0.995	0.000
T54.9 Corrosive substance, unspecified	0.005	0.995	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.005	0.995	0.000
S12.7 Multiple fractures of cervical spine	0.005	0.995	0.000
T59.7 Carbon dioxide	0.005	0.995	0.000
T59.6 Hydrogen sulphide	0.005	0.995	0.000
T59.5 Fluorine gas and hydrogen fluoride	0.005	0.995	0.000
T59.4 Chlorine gas	0.005	0.995	0.000
T59.3 Lachrymogenic gas	0.005	0.995	0.000
T59.2 Formaldehyde	0.005	0.995	0.000
T59.1 Sulphur dioxide	0.005	0.995	0.000
T59.0 Nitrogen oxides	0.005	0.995	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.005	0.995	0.000
T20.2 Burn of second degree of head and neck	0.005	0.995	0.000
T16 Foreign body in ear	0.005	0.995	0.000
S50.8 Other superficial injuries of forearm	0.005	0.995	0.000
S12.0 Fracture of first cervical vertebra	0.005	0.995	0.000
S13.5 Sprain and strain of thyroid region	0.005	0.995	0.000
S13.3 Multiple dislocations of neck	0.005	0.995	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.005	0.995	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.005	0.995	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.005	0.995	0.000
S31.5 Open wound of other and unspecified external genital organs	0.005	0.995	0.000
T56.9 Metal, unspecified	0.005	0.995	0.000
T56.7 Beryllium and its compounds	0.005	0.995	0.000
T56.6 Tin and its compounds	0.005	0.995	0.000
T56.5 Zinc and its compounds	0.005	0.995	0.000
T56.4 Copper and its compounds	0.005	0.995	0.000
T56.3 Cadmium and its compounds	0.005	0.995	0.000
T56.2 Chromium and its compounds	0.005	0.995	0.000
T56.1 Mercury and its compounds	0.005	0.995	0.000
T56.0 Lead and its compounds	0.005	0.995	0.000
T59.9 Gases, fumes and vapours, unspecified	0.005	0.995	0.000
T78.8 Other adverse effects, not elsewhere classified	0.005	0.995	0.000
S14.6 Injury of other and unspecified nerves of neck	0.005	0.995	0.000
S14.5 Injury of cervical sympathetic nerves	0.005	0.995	0.000
S14.4 Injury of peripheral nerves of neck	0.005	0.995	0.000
S14.2 Injury of nerve root of cervical spine	0.005	0.995	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.005	0.995	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.005	0.995	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.005	0.995	0.000
S71 Open wound of hip and thigh	0.005	0.995	0.000
S10.7 Multiple superficial injuries of neck	0.005	0.995	0.000
S10.0 Contusion of throat	0.005	0.995	0.000
S15.9 Injury of unspecified blood vessel at neck level	0.005	0.995	0.000
S15.8 Injury of other blood vessels at neck level	0.005	0.995	0.000
S15.7 Injury of multiple blood vessels at neck level	0.005	0.995	0.000
S15.3 Injury of internal jugular vein	0.005	0.995	0.000
S15.2 Injury of external jugular vein	0.005	0.995	0.000
S15.1 Injury of vertebral artery	0.005	0.995	0.000
S15.0 Injury of carotid artery	0.005	0.995	0.000
S17.9 Crushing injury of neck, part unspecified	0.005	0.995	0.000
S17.8 Crushing injury of other parts of neck	0.005	0.995	0.000
S17.0 Crushing injury of larynx and traches	0.005	0.995	0.000
S19.8 Other specified injuries of neck	0.005	0.995	0.000
S10.8 Superficial injury of other parts of neck	0.005	0.995	0.000
S50-S59 Injuries to the elbow and forearm	0.005	0.995	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.005	0.995	0.000
S31.4 Open wound of vagina and vulva	0.005	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations