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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1992625
log Bayes Factor = 10.9105
Chromosome 10   position 63,520,698  (GRCh37) Explore rs1992625 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
0.000 0.000 1.000
M81.98 Osteoporosis, unspecified (Other)
0.000 0.622 0.378
M81.9 Osteoporosis, unspecified
0.000 0.627 0.373
M81.90 Osteoporosis, unspecified (Multiple sites)
0.000 0.627 0.373
M81.99 Osteoporosis, unspecified (Site unspecified)
0.000 0.686 0.314
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.000 0.707 0.293
M81.96 Osteoporosis, unspecified (Lower leg)
0.000 0.719 0.281
M81.94 Osteoporosis, unspecified (Hand)
0.000 0.732 0.268
M81.92 Osteoporosis, unspecified (Upper arm)
0.000 0.732 0.268
M81.91 Osteoporosis, unspecified (Shoulder region)
0.000 0.732 0.268
M81.93 Osteoporosis, unspecified (Forearm)
0.000 0.754 0.246
I10-I15 Hypertensive diseases
0.000 0.762 0.238
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.000 0.765 0.235
I11 Hypertensive heart disease
0.000 0.824 0.176
I13 Hypertensive heart and renal disease
0.000 0.829 0.171
M81 Osteoporosis without pathological fracture
0.000 0.850 0.150
I15 Secondary hypertension
0.000 0.856 0.144
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.868 0.132
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.874 0.126
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.877 0.123
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.877 0.123
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.877 0.123
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.877 0.123
M81.2 Osteoporosis of disuse
0.000 0.887 0.113
M81.8 Other osteoporosis
0.000 0.892 0.107
M81.6 Localised osteoporosis [Lequesne]
0.000 0.892 0.107
M81.5 Idiopathic osteoporosis
0.000 0.892 0.107
M81.1 Postoophorectomy osteoporosis
0.000 0.892 0.107
M81.3 Postsurgical malabsorption osteoporosis
0.000 0.894 0.106
I15.8 Other secondary hypertension
0.000 0.897 0.103
I15.2 Hypertension secondary to endocrine disorders
0.000 0.897 0.103
I15.0 Renovascular hypertension
0.000 0.897 0.103
M81.0 Postmenopausal osteoporosis
0.000 0.898 0.101
I42 Cardiomyopathy
0.000 0.904 0.096
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.905 0.095
M81.4 Drug-induced osteoporosis
0.000 0.907 0.092
I15.9 Seconday hypertension, unspecified
0.000 0.908 0.092
I15.1 Hypertension secondary to other renal disorders
0.000 0.909 0.091
I42.0 Dilated cardiomyopathy
0.000 0.912 0.088
M81.20 Osteoporosis of disuse (Multiple sites)
0.000 0.913 0.087
I42.2 Other hypertrophic cardiomyopathy
0.000 0.915 0.085
M81.29 Osteoporosis of disuse (Site unspecified)
0.000 0.918 0.081
M81.28 Osteoporosis of disuse (Other)
0.000 0.918 0.081
M81.27 Osteoporosis of disuse (Ankle and foot)
0.000 0.918 0.081
M81.26 Osteoporosis of disuse (Lower leg)
0.000 0.918 0.081
M81.25 Osteoporosis of disuse (Pelvic region and thigh)
0.000 0.918 0.081
M81.24 Osteoporosis of disuse (Hand)
0.000 0.918 0.081
M81.23 Osteoporosis of disuse (Forearm)
0.000 0.918 0.081
M81.22 Osteoporosis of disuse (Upper arm)
0.000 0.918 0.081
M81.21 Osteoporosis of disuse (Shoulder region)
0.000 0.918 0.081
I42.9 Cardiomyopathy, unspecified
0.000 0.920 0.080
I42.6 Alcoholic cardiomyopathy
0.000 0.921 0.079
M81.19 Postoophorectomy osteoporosis (Site unspecified)
0.000 0.923 0.077
M81.18 Postoophorectomy osteoporosis (Other)
0.000 0.923 0.077
M81.17 Postoophorectomy osteoporosis (Ankle and foot)
0.000 0.923 0.077
M81.16 Postoophorectomy osteoporosis (Lower leg)
0.000 0.923 0.077
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)
0.000 0.923 0.077
M81.14 Postoophorectomy osteoporosis (Hand)
0.000 0.923 0.077
M81.13 Postoophorectomy osteoporosis (Forearm)
0.000 0.923 0.077
M81.12 Postoophorectomy osteoporosis (Upper arm)
0.000 0.923 0.077
M81.11 Postoophorectomy osteoporosis (Shoulder region)
0.000 0.923 0.077
M81.10 Postoophorectomy osteoporosis (Multiple sites)
0.000 0.923 0.077
M81.59 Idiopathic osteoporosis (Site unspecified)
0.000 0.923 0.077
M81.58 Idiopathic osteoporosis (Other)
0.000 0.923 0.077
M81.57 Idiopathic osteoporosis (Ankle and foot)
0.000 0.923 0.077
M81.56 Idiopathic osteoporosis (Lower leg)
0.000 0.923 0.077
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)
0.000 0.923 0.077
M81.54 Idiopathic osteoporosis (Hand)
0.000 0.923 0.077
M81.53 Idiopathic osteoporosis (Forearm)
0.000 0.923 0.077
M81.52 Idiopathic osteoporosis (Upper arm)
0.000 0.923 0.077
M81.51 Idiopathic osteoporosis (Shoulder region)
0.000 0.923 0.077
M81.50 Idiopathic osteoporosis (Multiple sites)
0.000 0.923 0.077
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)
0.000 0.923 0.077
M81.68 Localized osteoporosis [Lequesne] (Other)
0.000 0.923 0.077
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)
0.000 0.923 0.077
M81.66 Localized osteoporosis [Lequesne] (Lower leg)
0.000 0.923 0.077
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)
0.000 0.923 0.077
M81.64 Localized osteoporosis [Lequesne] (Hand)
0.000 0.923 0.077
M81.63 Localized osteoporosis [Lequesne] (Forearm)
0.000 0.923 0.077
M81.62 Localized osteoporosis [Lequesne] (Upper arm)
0.000 0.923 0.077
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)
0.000 0.923 0.077
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)
0.000 0.923 0.077
M81.89 Other osteoporosis (Site unspecified)
0.000 0.923 0.077
M81.88 Other osteoporosis (Other)
0.000 0.923 0.077
M81.87 Other osteoporosis (Ankle and foot)
0.000 0.923 0.077
M81.86 Other osteoporosis (Lower leg)
0.000 0.923 0.077
M81.85 Other osteoporosis (Pelvic region and thigh)
0.000 0.923 0.077
M81.84 Other osteoporosis (Hand)
0.000 0.923 0.077
M81.83 Other osteoporosis (Forearm)
0.000 0.923 0.077
M81.82 Other osteoporosis (Upper arm)
0.000 0.923 0.077
M81.81 Other osteoporosis (Shoulder region)
0.000 0.923 0.077
M81.80 Other osteoporosis (Multiple sites)
0.000 0.923 0.077
Chapter IX Diseases of the circulatory system
0.000 0.923 0.077
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)
0.000 0.924 0.076
M81.38 Postsurgical malabsorption osteoporosis (Other)
0.000 0.924 0.076
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)
0.000 0.924 0.076
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)
0.000 0.924 0.076
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)
0.000 0.924 0.076
M81.34 Postsurgical malabsorption osteoporosis (Hand)
0.000 0.924 0.076
M81.33 Postsurgical malabsorption osteoporosis (Forearm)
0.000 0.924 0.076
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)
0.000 0.924 0.076
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)
0.000 0.924 0.076
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)
0.000 0.925 0.075
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.926 0.074
I26 Pulmonary embolism
0.000 0.926 0.074
M81.08 Postmenopausal osteoporosis (Other)
0.000 0.927 0.073
M81.07 Postmenopausal osteoporosis (Ankle and foot)
0.000 0.927 0.073
M81.06 Postmenopausal osteoporosis (Lower leg)
0.000 0.927 0.073
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)
0.000 0.927 0.073
M81.04 Postmenopausal osteoporosis (Hand)
0.000 0.927 0.073
M81.03 Postmenopausal osteoporosis (Forearm)
0.000 0.927 0.073
M81.02 Postmenopausal osteoporosis (Upper arm)
0.000 0.927 0.073
M81.01 Postmenopausal osteoporosis (Shoulder region)
0.000 0.927 0.073
M81.00 Postmenopausal osteoporosis (Multiple sites)
0.000 0.927 0.073
I30-I52 Other forms of heart disease
0.000 0.927 0.073
I38 Endocarditis, valve unspecified
0.000 0.928 0.072
I25.2 Old myocardial infarction
0.000 0.928 0.072
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.929 0.071
M81.49 Drug-induced osteoporosis (Site unspecified)
0.000 0.930 0.070
I05-I09 Chronic rheumatic heart diseases
0.000 0.930 0.070
I42.5 Other restrictive cardiomyopathy
0.000 0.931 0.069
I42.4 Endocardial fibroelastosis
0.000 0.931 0.069
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.931 0.069
I46 Cardiac arrest
0.000 0.932 0.068
M81.09 Postmenopausal osteoporosis (Site unspecified)
0.000 0.933 0.067
M81.48 Drug-induced osteoporosis (Other)
0.000 0.933 0.066
M81.47 Drug-induced osteoporosis (Ankle and foot)
0.000 0.933 0.066
M81.46 Drug-induced osteoporosis (Lower leg)
0.000 0.933 0.066
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)
0.000 0.933 0.066
M81.44 Drug-induced osteoporosis (Hand)
0.000 0.933 0.066
M81.43 Drug-induced osteoporosis (Forearm)
0.000 0.933 0.066
M81.42 Drug-induced osteoporosis (Upper arm)
0.000 0.933 0.066
M81.41 Drug-induced osteoporosis (Shoulder region)
0.000 0.933 0.066
I46.0 Cardiac arrest with successful resuscitation
0.000 0.935 0.065
I25 Chronic ischaemic heart disease
0.000 0.935 0.065
I35 Nonrheumatic aortic valve disorders
0.000 0.935 0.065
I42.8 Other cardiomyopathies
0.000 0.935 0.065
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.935 0.065
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.937 0.063
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.937 0.063
I08 Multiple valve diseases
0.000 0.937 0.063
I12 Hypertensive renal disease
0.000 0.938 0.062
I20-I25 Ischaemic heart diseases
0.000 0.939 0.061
I05 Rheumatic mitral valve diseases
0.000 0.942 0.058
I25.4 Coronary artery aneurysm
0.000 0.943 0.057
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.944 0.056
I35.8 Other aortic valve disorders
0.000 0.944 0.056
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.944 0.056
I28 Other diseases of pulmonary vessels
0.000 0.944 0.056
I36 Nonrheumatic tricuspid valve disorders
0.000 0.945 0.055
I07 Rheumatic tricuspid valve diseases
0.000 0.946 0.054
I40 Acute myocarditis
0.000 0.947 0.053
I52 Other heart disorders in diseases classified elsewhere
0.000 0.947 0.052
I48 Atrial fibrillation and flutter
0.000 0.947 0.052
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.947 0.052
I41 Myocarditis in diseases classified elsewhere
0.000 0.947 0.052
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.947 0.052
I32 Pericarditis in diseases classified elsewhere
0.000 0.947 0.052
I35.1 Aortic (valve) insufficiency
0.000 0.948 0.052
I08.8 Other multiple valve diseases
0.000 0.948 0.052
I05.9 Mitral valve disease, unspecified
0.000 0.948 0.052
I06 Rheumatic aortic valve diseases
0.000 0.948 0.051
I00-I02 Acute rheumatic fever
0.000 0.949 0.051
I44 Atrioventricular and left bundle-branch block
0.000 0.950 0.050
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.951 0.049
I44.0 Atrioventricular block, first degree
0.000 0.951 0.049
I46.1 Sudden cardiac death, so described
0.000 0.951 0.049
I31 Other diseases of pericardium
0.000 0.952 0.048
I33 Acute and subacute endocarditis
0.000 0.952 0.048
I05.1 Rheumatic mitral insufficiency
0.000 0.953 0.046
I35.9 Aortic valve disorder, unspecified
0.000 0.954 0.046
I44.1 Atrioventricular block, second degree
0.000 0.954 0.046
I27 Other pulmonary heart diseases
0.000 0.954 0.046
M81.40 Drug-induced osteoporosis (Multiple sites)
0.000 0.954 0.046
I37 Pulmonary valve disorders
0.000 0.954 0.046
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.954 0.046
I30 Acute pericarditis
0.000 0.955 0.045
I08.9 Multiple valve disease, unspecified
0.000 0.955 0.045
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.955 0.045
I05.2 Mitral stenosis with insufficiency
0.000 0.957 0.043
I28.8 Other specified diseases of pulmonary vessels
0.000 0.957 0.042
I46.9 Cardiac arrest, unspecified
0.000 0.958 0.042
I07.1 Tricuspid insufficiency
0.000 0.958 0.042
I05.8 Other mitral valve diseases
0.000 0.958 0.042
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.959 0.041
I23 Certain current complications following acute myocardial infarction
0.000 0.959 0.041
I08.0 Disorders of both mitral and aortic valves
0.000 0.959 0.041
I31.3 Pericardial effusion (noninflammatory)
0.000 0.959 0.041
I25.6 Silent myocardial ischaemia
0.000 0.959 0.041
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.960 0.040
I28.1 Aneurysm of pulmonary artery
0.000 0.960 0.040
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.960 0.040
M41.99 Scoliosis, unspecified (Site unspecified)
0.040 0.960 0.000
M41.9 Scoliosis, unspecified
0.040 0.960 0.000
I27.9 Pulmonary heart disease, unspecified
0.000 0.960 0.040
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.961 0.039
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.961 0.039
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.961 0.039
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.961 0.039
I07.9 Tricuspid valve disease, unspecified
0.000 0.961 0.039
I07.8 Other tricuspid valve diseases
0.000 0.961 0.039
I07.2 Tricuspid stenosis with insufficiency
0.000 0.961 0.039
I07.0 Tricuspid stenosis
0.000 0.961 0.039
I06.0 Rheumatic aortic stenosis
0.000 0.961 0.038
I40.0 Infective myocarditis
0.000 0.962 0.038
I40.9 Acute myocarditis, unspecified
0.000 0.962 0.038
I40.8 Other acute myocarditis
0.000 0.962 0.038
I40.1 Isolated myocarditis
0.000 0.962 0.038
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.962 0.038
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.962 0.038
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.962 0.038
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.962 0.038
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.962 0.038
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.962 0.038
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.962 0.038
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.962 0.038
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.962 0.038
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.962 0.038
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.962 0.038
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.962 0.038
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.962 0.038
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.962 0.038
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.962 0.038
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.962 0.038
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.962 0.038
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.962 0.038
I48.4 Atypical atrial flutter
0.000 0.962 0.038
I48.3 Typical atrial flutter
0.000 0.962 0.038
I48.2 Chronic atrial fibrillation
0.000 0.962 0.038
I48.1 Persistent atrial fibrillation
0.000 0.962 0.038
I48.0 Paroxysmal atrial fibrillation
0.000 0.962 0.038
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.962 0.038
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.962 0.038
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.962 0.038
I09 Other rheumatic heart diseases
0.001 0.963 0.037
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.963 0.037
I06.8 Other rheumatic aortic valve diseases
0.000 0.963 0.037
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.963 0.037
I06.1 Rheumatic aortic insufficiency
0.000 0.963 0.037
I02 Rheumatic chorea
0.000 0.963 0.037
I01 Rheumatic fever with heart involvement
0.000 0.963 0.037
M41.94 Scoliosis, unspecified (Thoracic region)
0.037 0.963 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.037 0.963 0.000
I44.5 Left posterior fascicular block
0.000 0.964 0.036
I44.4 Left anterior fascicular block
0.000 0.964 0.036
I25.5 Ischaemic cardiomyopathy
0.000 0.964 0.036
I25.3 Aneurysm of heart
0.000 0.964 0.036
I22 Subsequent myocardial infarction
0.000 0.965 0.035
I27.8 Other specified pulmonary heart diseases
0.000 0.965 0.035
I31.8 Other specified diseases of pericardium
0.000 0.965 0.034
I31.2 Haemopericardium, not elsewhere classified
0.000 0.965 0.034
I30.9 Acute pericarditis, unspecified
0.000 0.966 0.034
I31.1 Chronic constrictive pericarditis
0.000 0.966 0.034
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.034 0.966 0.000
I33.9 Acute endocarditis, unspecified
0.000 0.967 0.033
I27.1 Kyphoscoliotic heart disease
0.000 0.967 0.033
I37.9 Pulmonary valve disorder, unspecified
0.000 0.967 0.033
I37.8 Other pulmonary valve disorders
0.000 0.967 0.033
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.967 0.033
I00 Rheumatic fever without mention of heart involvement
0.000 0.967 0.033
M80-M85 Disorders of bone density and structure
0.000 0.967 0.033
I30.8 Other forms of acute pericarditis
0.000 0.967 0.033
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.967 0.033
I33.0 Acute and subacute infective endocarditis
0.000 0.969 0.031
I21 Acute myocardial infarction
0.000 0.970 0.030
I31.0 Chronic adhesive pericarditis
0.000 0.970 0.030
I37.1 Pulmonary valve insufficiency
0.000 0.970 0.030
I37.0 Pulmonary valve stenosis
0.000 0.970 0.030
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.970 0.030
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.970 0.030
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.970 0.030
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.970 0.030
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.970 0.030
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.970 0.030
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.970 0.030
I27.2 Other secondary pulmonary hypertension
0.000 0.970 0.030
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.029 0.971 0.000
S52.10 Fracture of upper end of radius (closed)
0.000 0.971 0.029
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.029 0.971 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.029 0.971 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.029 0.971 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.029 0.971 0.000
I20 Angina pectoris
0.000 0.972 0.028
I22.8 Subsequent myocardial infarction of other sites
0.000 0.973 0.027
I23.8 Other current complications following acute myocardial infarction
0.000 0.973 0.027
I09.8 Other specified rheumatic heart diseases
0.001 0.973 0.027
I09.2 Chronic rheumatic pericarditis
0.001 0.973 0.027
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.001 0.973 0.027
I09.0 Rheumatic myocarditis
0.001 0.973 0.027
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.027 0.973 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.973 0.027
I01.8 Other acute rheumatic heart disease
0.000 0.973 0.027
I01.2 Acute rheumatic myocarditis
0.000 0.973 0.027
I01.1 Acute rheumatic endocarditis
0.000 0.973 0.027
I01.0 Acute rheumatic pericarditis
0.000 0.973 0.027
I02.9 Rheumatic chorea without heart involvement
0.000 0.973 0.027
I02.0 Rheumatic chorea with heart involvement
0.000 0.973 0.027
I35.0 Aortic (valve) stenosis
0.000 0.973 0.027
I05.0 Mitral stenosis
0.000 0.974 0.026
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.974 0.026
K86.1 Other chronic pancreatitis
0.025 0.975 0.000
M80 Osteoporosis with pathological fracture
0.000 0.975 0.025
I44.3 Other and unspecified atrioventricular block
0.000 0.975 0.024
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.975 0.025
I31.9 Disease of pericardium, unspecified
0.000 0.976 0.024
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.976 0.024
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.976 0.024
M83 Adult osteomalacia
0.000 0.976 0.024
M41 Scoliosis
0.024 0.976 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.977 0.023
I20.1 Angina pectoris with documented spasm
0.000 0.977 0.023
I30.1 Infective pericarditis
0.000 0.977 0.022
M82 Osteoporosis in diseases classified elsewhere
0.000 0.978 0.022
Z22.3 Carrier of other specified bacterial diseases
0.000 0.978 0.022
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.978 0.022
M85 Other disorders of bone density and structure
0.000 0.978 0.022
M80.0 Postmenopausal osteoporosis with pathological fracture
0.000 0.979 0.021
I20.9 Angina pectoris, unspecified
0.000 0.980 0.020
M80.5 Idiopathic osteoporosis with pathological fracture
0.000 0.980 0.020
I21.9 Acute myocardial infarction, unspecified
0.000 0.980 0.020
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.980 0.020
I34 Nonrheumatic mitral valve disorders
0.000 0.981 0.019
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.000 0.981 0.019
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.981 0.019
M41.8 Other forms of scoliosis
0.019 0.981 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.981 0.019
I12.9 Hypertensive renal disease without renal failure
0.000 0.981 0.018
I44.6 Other and unspecified fascicular block
0.000 0.981 0.018
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.000 0.982 0.018
I20.8 Other forms of angina pectoris
0.000 0.982 0.018
M85.8 Other specified disorders of bone density and structure
0.000 0.982 0.018
M80.4 Drug-induced osteoporosis with pathological fracture
0.000 0.982 0.018
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.000 0.982 0.018
M80.2 Osteoporosis of disuse with pathological fracture
0.000 0.982 0.018
M41.5 Other secondary scoliosis
0.018 0.982 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.000 0.982 0.017
M83.9 Adult osteomalacia, unspecified
0.000 0.983 0.017
M83.8 Other adult osteomalacia
0.000 0.983 0.017
M83.5 Other drug-induced osteomalacia in adults
0.000 0.983 0.017
M83.4 Aluminum bone disease
0.000 0.983 0.017
M83.3 Adult osteomalacia due to malnutrition
0.000 0.983 0.017
M83.2 Adult osteomalacia due to malabsorption
0.000 0.983 0.017
M83.1 Senile osteomalacia
0.000 0.983 0.017
M83.0 Puerperal osteomalacia
0.000 0.983 0.017
M41.4 Neuromuscular scoliosis
0.017 0.983 0.000
M41.3 Thoracogenic scoliosis
0.017 0.983 0.000
M41.2 Other idiopathic scoliosis
0.017 0.983 0.000
M41.1 Juvenile idiopathic scoliosis
0.017 0.983 0.000
M41.0 Infantile idiopathic scoliosis
0.017 0.983 0.000
Z22 Carrier of infectious disease
0.000 0.983 0.017
I44.2 Atrioventricular block, complete
0.000 0.984 0.016
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.000 0.984 0.016
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.984 0.016
M82.8 Osteoporosis in other diseases classified elsewhere
0.000 0.984 0.016
M82.0 Osteoporosis in multiple myelomatosis
0.000 0.984 0.016
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.000 0.984 0.016
M80.8 Other osteoporosis with pathological fracture
0.000 0.984 0.016
M85.9 Disorder of bone density and structure, unspecified
0.000 0.984 0.016
M85.5 Aneurysmal bone cyst
0.000 0.984 0.016
M85.4 Solitary bone cyst
0.000 0.984 0.016
M85.3 Osteitis condensans
0.000 0.984 0.016
M85.2 Hyperostosis of skull
0.000 0.984 0.016
M85.1 Skeletal fluorosis
0.000 0.984 0.016
I49 Other cardiac arrhythmias
0.000 0.984 0.016
M85.0 Fibrous dysplasia (monostotic)
0.000 0.984 0.016
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)
0.000 0.984 0.016
Z22.1 Carrier of other intestinal infectious diseases
0.000 0.985 0.015
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)
0.000 0.985 0.015
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)
0.000 0.985 0.015
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)
0.000 0.985 0.015
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)
0.000 0.985 0.015
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.985 0.015
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)
0.000 0.985 0.015
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)
0.000 0.985 0.015
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)
0.000 0.985 0.015
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)
0.000 0.985 0.015
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)
0.000 0.985 0.015
I49.0 Ventricular fibrillation and flutter
0.000 0.985 0.015
M41.86 Other forms of scoliosis (Lumbar region)
0.015 0.985 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.985 0.015
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.985 0.015
M82.1 Osteoporosis in endocrine disorders
0.000 0.985 0.014
I09.9 Rheumatic heart disease, unspecified
0.001 0.985 0.013
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)
0.000 0.986 0.014
M80.58 Idiopathic osteoporosis with pathological fracture (Other)
0.000 0.986 0.014
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)
0.000 0.986 0.014
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)
0.000 0.986 0.014
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.986 0.014
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)
0.000 0.986 0.014
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)
0.000 0.986 0.014
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)
0.000 0.986 0.014
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.986 0.014
I24 Other acute ischaemic heart diseases
0.000 0.986 0.014
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.986 0.014
M41.56 Other secondary scoliosis (Lumbar region)
0.014 0.986 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.000 0.986 0.014
I44.7 Left bundle-branch block, unspecified
0.000 0.986 0.014
M41.89 Other forms of scoliosis (Site unspecified)
0.013 0.986 0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)
0.013 0.986 0.000
M41.87 Other forms of scoliosis (Lumbosacral region)
0.013 0.986 0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)
0.013 0.986 0.000
M41.84 Other forms of scoliosis (Thoracic region)
0.013 0.986 0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)
0.013 0.986 0.000
M41.82 Other forms of scoliosis (Cervical region)
0.013 0.986 0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)
0.013 0.986 0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)
0.013 0.986 0.000
M84 Disorders of continuity of bone
0.000 0.986 0.014
I47 Paroxysmal tachycardia
0.000 0.986 0.014
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.000 0.987 0.013
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.000 0.987 0.013
M85.84 Other specified disorders of bone density and structure (Hand)
0.000 0.987 0.013
M85.83 Other specified disorders of bone density and structure (Forearm)
0.000 0.987 0.013
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.000 0.987 0.013
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.000 0.987 0.013
I25.1 Atherosclerotic heart disease
0.000 0.987 0.013
Z22.5 Carrier of viral hepatitis
0.000 0.987 0.013
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)
0.000 0.987 0.013
M80.28 Osteoporosis of disuse with pathological fracture (Other)
0.000 0.987 0.013
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)
0.000 0.987 0.013
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)
0.000 0.987 0.013
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)
0.000 0.987 0.013
M80.24 Osteoporosis of disuse with pathological fracture (Hand)
0.000 0.987 0.013
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)
0.000 0.987 0.013
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)
0.000 0.987 0.013
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)
0.000 0.987 0.013
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)
0.000 0.987 0.013
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)
0.000 0.987 0.013
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)
0.000 0.987 0.013
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)
0.000 0.987 0.013
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)
0.000 0.987 0.013
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.987 0.013
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)
0.000 0.987 0.013
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)
0.000 0.987 0.013
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)
0.000 0.987 0.013
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)
0.000 0.987 0.013
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)
0.000 0.987 0.013
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)
0.000 0.987 0.013
M80.48 Drug-induced osteoporosis with pathological fracture (Other)
0.000 0.987 0.013
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)
0.000 0.987 0.013
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)
0.000 0.987 0.013
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.987 0.013
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)
0.000 0.987 0.013
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)
0.000 0.987 0.013
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)
0.000 0.987 0.013
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)
0.000 0.987 0.013
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)
0.000 0.987 0.013
M41.59 Other secondary scoliosis (Site unspecified)
0.013 0.987 0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)
0.013 0.987 0.000
M41.57 Other secondary scoliosis (Lumbosacral region)
0.013 0.987 0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)
0.013 0.987 0.000
M41.54 Other secondary scoliosis (Thoracic region)
0.013 0.987 0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)
0.013 0.987 0.000
M41.52 Other secondary scoliosis (Cervical region)
0.013 0.987 0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)
0.013 0.987 0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)
0.013 0.987 0.000
Z22.8 Carrier of other infectious diseases
0.000 0.987 0.013
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)
0.000 0.987 0.013
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)
0.000 0.987 0.013
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)
0.000 0.987 0.013
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)
0.000 0.987 0.013
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.987 0.013
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)
0.000 0.987 0.013
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)
0.000 0.987 0.013
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)
0.000 0.987 0.013
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)
0.000 0.987 0.013
I45 Other conduction disorders
0.000 0.987 0.013
S52.1 Fracture of upper end of radius
0.000 0.987 0.013
M83.09 Puerperal osteomalacia (Site unspecified)
0.000 0.987 0.012
M83.08 Puerperal osteomalacia (Other)
0.000 0.987 0.012
M83.07 Puerperal osteomalacia (Ankle and foot)
0.000 0.987 0.012
M83.06 Puerperal osteomalacia (Lower leg)
0.000 0.987 0.012
M83.05 Puerperal osteomalacia (Pelvic region and thigh)
0.000 0.987 0.012
M83.04 Puerperal osteomalacia (Hand)
0.000 0.987 0.012
M83.03 Puerperal osteomalacia (Forearm)
0.000 0.987 0.012
M83.02 Puerperal osteomalacia (Upper arm)
0.000 0.987 0.012
M83.01 Puerperal osteomalacia (Shoulder region)
0.000 0.987 0.012
M83.00 Puerperal osteomalacia (Multiple sites)
0.000 0.987 0.012
M83.19 Senile osteomalacia (Site unspecified)
0.000 0.987 0.012
M83.18 Senile osteomalacia (Other)
0.000 0.987 0.012
M83.17 Senile osteomalacia (Ankle and foot)
0.000 0.987 0.012
M83.16 Senile osteomalacia (Lower leg)
0.000 0.987 0.012
M83.15 Senile osteomalacia (Pelvic region and thigh)
0.000 0.987 0.012
M83.14 Senile osteomalacia (Hand)
0.000 0.987 0.012
M83.13 Senile osteomalacia (Forearm)
0.000 0.987 0.012
M83.12 Senile osteomalacia (Upper arm)
0.000 0.987 0.012
M83.11 Senile osteomalacia (Shoulder region)
0.000 0.987 0.012
M83.10 Senile osteomalacia (Multiple sites)
0.000 0.987 0.012
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)
0.000 0.987 0.012
M83.28 Adult osteomalacia due to malabsorption (Other)
0.000 0.987 0.012
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)
0.000 0.987 0.012
M83.26 Adult osteomalacia due to malabsorption (Lower leg)
0.000 0.987 0.012
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)
0.000 0.987 0.012
M83.24 Adult osteomalacia due to malabsorption (Hand)
0.000 0.987 0.012
M83.23 Adult osteomalacia due to malabsorption (Forearm)
0.000 0.987 0.012
M83.22 Adult osteomalacia due to malabsorption (Upper arm)
0.000 0.987 0.012
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)
0.000 0.987 0.012
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)
0.000 0.987 0.012
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)
0.000 0.987 0.012
M83.38 Adult osteomalacia due to malnutrition (Other)
0.000 0.987 0.012
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)
0.000 0.987 0.012

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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