TreeWAS – Variant ID: rs201435717

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.997	0.003
S00-S09 Injuries to the head	0.990	0.010
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.969	0.031
T81 Complications of procedures, not elsewhere classified	0.956	0.044
S01 Open wound of head	0.948	0.052
# Top node	0.923	0.077
Chapter XV Pregnancy, childbirth and the puerperium	0.921	0.079
Chapter XX External causes of morbidity and mortality	0.921	0.079
S40-S49 Injuries to the shoulder and upper arm	0.917	0.083
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.909	0.091
O60-O75 Complications of labour and delivery	0.908	0.092
S00 Superficial injury of head	0.907	0.093
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.903	0.097
S80-S89 Injuries to the knee and lower leg	0.899	0.101
S60-S69 Injuries to the wrist and hand	0.889	0.111
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.867	0.133
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.862	0.138
S06 Intracranial injury	0.858	0.142
Chapter V Mental and behavioural disorders	0.856	0.144
S00.9 Superficial injury of head, part unspecified	0.854	0.146
T81.4 Infection following a procedure, not elsewhere classified	0.851	0.149
T36-T50 Poisoning by drugs, medicaments and biological substances	0.851	0.149
W00-W19 Falls	0.850	0.150
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.850	0.150
S01.5 Open wound of lip and oral cavity	0.844	0.156
F30-F39 Mood [affective] disorders	0.840	0.160
O68 Labour and delivery complicated by foetal stress [distress]	0.834	0.166
F31 Bipolar affective disorder	0.830	0.170
S01.0 Open wound of scalp	0.827	0.173
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.816	0.184
O63 Long labour	0.799	0.201
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.792	0.208
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.791	0.209
T15-T19 Effects of foreign body entering through natural orifice	0.790	0.210
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.789	0.211
W19 Unspecified fall	0.789	0.211
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.786	0.214
S49 Other and unspecified injuries of shoulder and upper arm	0.785	0.215
Chapter VIII Diseases of the ear and mastoid process	0.783	0.217
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.782	0.218
S02 Fracture of skull and facial bones	0.779	0.221
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.777	0.223
S66 Injury of muscle and tendon at wrist and hand level	0.775	0.225
V10-V19 Pedal cyclist injured in transport accident	0.774	0.226
S50-S59 Injuries to the elbow and forearm	0.774	0.226
S01.1 Open wound of eyelid and periocular area	0.772	0.228
S82 Fracture of lower leg, including ankle	0.770	0.230
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.768	0.232
S46 Injury of muscle and tendon at shoulder and upper arm level	0.767	0.233
O80-O84 Delivery	0.766	0.233
Y83.8 Other surgical procedures	0.759	0.241
S42 Fracture of shoulder and upper arm	0.757	0.243
Y84.8 Other medical procedures	0.757	0.243
Y83.2 Surgical operation with anastomosis, bypass or graft	0.755	0.245
T81.9 Unspecified complication of procedure	0.753	0.247
T81.8 Other complications of procedures, not elsewhere classified	0.748	0.252
O32 Maternal care for known or suspected malpresentation of foetus	0.746	0.254
Chapter XXII Codes for special purposes	0.745	0.255
T51 Toxic effect of alcohol	0.743	0.257
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.740	0.260
O66 Other obstructed labour	0.735	0.264
S64 Injury of nerves at wrist and hand level	0.734	0.266
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.733	0.267
S80 Superficial injury of lower leg	0.732	0.268
O46 Antepartum haemorrhage, not elsewhere classified	0.729	0.270
T66-T78 Other and unspecified effects of external causes	0.729	0.271
S90-S99 Injuries to the ankle and foot	0.720	0.280
O70 Perineal laceration during delivery	0.719	0.281
O61 Failed induction of labour	0.719	0.281
W19.9 Unspecified place	0.718	0.282
S20-S29 Injuries to the thorax	0.717	0.283
S01.9 Open wound of head, part unspecified	0.716	0.284
T84.0 Mechanical complication of internal joint prosthesis	0.715	0.284
T79-T79 Certain early complications of trauma	0.715	0.285
T33-T35 Frostbite	0.715	0.285
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
T20-T25 Burns and corrosions of external body surface, specified by site	0.715	0.285
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.715	0.285
T00-T07 Injuries involving multiple body regions	0.715	0.285
S10-S19 Injuries to the neck	0.715	0.285
Y83.1 Surgical operation with implant of artificial internal device	0.713	0.287
S70-S79 Injuries to the hip and thigh	0.712	0.288
Chapter VII Diseases of the eye and adnexa	0.712	0.288
S08 Traumatic amputation of part of head	0.710	0.290
S07 Crushing injury of head	0.710	0.290
S05 Injury of eye and orbit	0.710	0.290
S04 Injury of cranial nerves	0.710	0.290
S03 Dislocation, sprain and strain of joints and ligaments of head	0.710	0.290
Y84.0 Cardiac catheterisation	0.710	0.290
S09 Other and unspecified injuries of head	0.710	0.290
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.709	0.291
O34 Maternal care for known or suspected abnormality of pelvic organs	0.708	0.291
F31.9 Bipolar affective disorder, unspecified	0.708	0.292
F31.0 Bipolar affective disorder, current episode hypomanic	0.708	0.292
V80-V89 Other land transport accidents	0.707	0.293
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.707	0.293
O94-O99 Other obstetric conditions, not elsewhere classified	0.704	0.296
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.704	0.296
S82.8 Fractures of other parts of lower leg	0.702	0.298
S81 Open wound of lower leg	0.698	0.302
Y83.3 Surgical operation with formation of external stoma	0.696	0.304
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.696	0.304
T87 Complications peculiar to reattachment and amputation	0.694	0.305
T86 Failure and rejection of transplanted organs and tissues	0.694	0.305
T80 Complications following infusion, transfusion and therapeutic injection	0.694	0.305
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.692	0.308
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.692	0.308
O63.1 Prolonged second stage (of labour)	0.690	0.310
S49.9 Unspecified injury of shoulder and upper arm	0.690	0.310
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.689	0.311
T88 Other complications of surgical and medical care, not elsewhere classified	0.688	0.312
O72 Postpartum haemorrhage	0.687	0.313
Chapter I Certain infectious and parasitic diseases	0.687	0.313
T81.7 Vascular complications following a procedure, not elsewhere classified	0.686	0.314
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.686	0.314
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.686	0.314
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.686	0.314
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.685	0.315
Q20-Q28 Congenital malformations of the circulatory system	0.683	0.316
S06.2 Diffuse brain injury	0.683	0.317
S06.6 Traumatic subarachnoid haemorrhage	0.682	0.318
S01.7 Multiple open wounds of head	0.680	0.320
S01.4 Open wound of cheek and temporomandibular area	0.680	0.320
S01.3 Open wound of ear	0.680	0.320
S01.2 Open wound of nose	0.680	0.320
S06.5 Traumatic subdural haemorrhage	0.675	0.325
O64 Obstructed labour due to malposition and malpresentation of foetus	0.669	0.331
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.668	0.332
T63 Toxic effect of contact with venomous animals	0.664	0.336
Y83.9 Surgical procedure, unspecified	0.663	0.337
Y60-Y69 Misadventures to patients during surgical and medical care	0.662	0.337
Chapter XVI Certain conditions originating in the perinatal period	0.662	0.338
O85-O92 Complications predominantly related to the puerperium	0.660	0.340
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.660	0.340
Y35-Y36 Legal intervention and operations of war	0.660	0.340
Y10-Y34 Event of undetermined intent	0.660	0.340
Y00-Y09 Assault	0.660	0.340
X85-X99 Assault	0.660	0.340
X58-X59 Accidental exposure to other and unspecified factors	0.660	0.340
X50-X57 Overexertion, travel and privation	0.660	0.340
X40-X49 Accidental poisoning by and exposure to noxious substances	0.660	0.340
X30-X39 Exposure to forces of nature	0.660	0.340
X20-X29 Contact with venomous animals and plants	0.660	0.340
X10-X19 Contact with heat and hot substances	0.660	0.340
X00-X09 Exposure to smoke, fire and flames	0.660	0.340
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.660	0.340
W75-W84 Other accidental threats to breathing	0.660	0.340
W65-W74 Accidental drowning and submersion	0.660	0.340
W50-W64 Exposure to animate mechanical forces	0.660	0.340
V98-V99 Other and unspecified transport accidents	0.660	0.340
V95-V97 Air and space transport accidents	0.660	0.340
V90-V94 Water transport accidents	0.660	0.340
V70-V79 Bus occupant injured in transport accident	0.660	0.340
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.660	0.340
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.660	0.340
V40-V49 Car occupant injured in transport accident	0.660	0.340
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.660	0.340
V01-V09 Pedestrian injured in transport accident	0.660	0.340
S46.0 Injury of tendon of the rotator cuff of shoulder	0.660	0.340
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.659	0.341
T51.0 Ethanol	0.658	0.342
S48 Traumatic amputation of shoulder and upper arm	0.658	0.342
S45 Injury of blood vessels at shoulder and upper arm level	0.658	0.342
S44 Injury of nerves at shoulder and upper arm level	0.658	0.342
S41 Open wound of shoulder and upper arm	0.658	0.342
S40 Superficial injury of shoulder and upper arm	0.658	0.342
S47 Crushing injury of shoulder and upper arm	0.658	0.342
O20-O29 Other maternal disorders predominantly related to pregnancy	0.655	0.345
S67 Crushing injury of wrist and hand	0.654	0.345
W10 Fall on and from stairs and steps	0.653	0.347
W20-W49 Exposure to inanimate mechanical forces	0.653	0.347
S00.0 Superficial injury of scalp	0.653	0.347
S82.80 Fractures of other parts of lower leg (closed)	0.653	0.347
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.652	0.347
O75 Other complications of labour and delivery, not elsewhere classified	0.651	0.349
O74 Complications of anaesthesia during labour and delivery	0.651	0.349
O73 Retained placenta and membranes, without haemorrhage	0.651	0.349
O71 Other obstetric trauma	0.651	0.349
O69 Labour and delivery complicated by umbilical cord complications	0.651	0.349
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.651	0.349
O65 Obstructed labour due to maternal pelvic abnormality	0.651	0.349
O60 Preterm delivery	0.651	0.349
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.651	0.349
S00.7 Multiple superficial injuries of head	0.650	0.350
S00.5 Superficial injury of lip and oral cavity	0.650	0.350
S00.4 Superficial injury of ear	0.650	0.350
S00.3 Superficial injury of nose	0.650	0.350
S00.2 Other superficial injuries of eyelid and periocular area	0.650	0.350
S00.1 Contusion of eyelid and periocular area	0.650	0.350
S42.3 Fracture of shaft of humerus	0.650	0.350
V20-V29 Motorcycle rider injured in transport accident	0.649	0.351
S01.8 Open wound of other parts of head	0.649	0.351
O62 Abnormalities of forces of labour	0.648	0.352
T43.2 Other and unspecified antidepressants	0.648	0.352
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.647	0.353
X60-X84 Intentional self-harm	0.647	0.353
F33 Recurrent depressive disorder	0.646	0.354
H60-H62 Diseases of external ear	0.646	0.354
V19 Pedal cyclist injured in other and unspecified transport accidents	0.645	0.354
O82 Single delivery by Caesarean section	0.645	0.355
S89 Other and unspecified injuries of lower leg	0.645	0.355
S88 Traumatic amputation of lower leg	0.645	0.355
S87 Crushing injury of lower leg	0.645	0.355
S86 Injury of muscle and tendon at lower leg level	0.645	0.355
S85 Injury of blood vessels at lower leg level	0.645	0.355
S84 Injury of nerves at lower leg level	0.645	0.355
O46.9 Antepartum haemorrhage, unspecified	0.643	0.357
T91 Sequelae of injuries of neck and trunk	0.642	0.358
T17 Foreign body in respiratory tract	0.641	0.358
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.641	0.359
O41 Other disorders of amniotic fluid and membranes	0.640	0.360
W19.4 Street and highway	0.640	0.360
S51 Open wound of forearm	0.639	0.361
S62 Fracture at wrist and hand level	0.639	0.361
O70.1 Second degree perineal laceration during delivery	0.638	0.362
O63.0 Prolonged first stage (of labour)	0.638	0.362
S69 Other and unspecified injuries of wrist and hand	0.638	0.362
S65 Injury of blood vessels at wrist and hand level	0.638	0.362
S60 Superficial injury of wrist and hand	0.638	0.362
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.637	0.363
O36 Maternal care for other known or suspected foetal problems	0.634	0.366
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.634	0.366
O32.1 Maternal care for breech presentation	0.632	0.368
Y83.4 Other reconstructive surgery	0.631	0.369
S02.5 Fracture of tooth	0.625	0.375
S02.1 Fracture of base of skull	0.624	0.376
S82.6 Fracture of lateral malleolus	0.622	0.378
Y83.5 Amputation of limb(s)	0.622	0.378
Y83.0 Surgical operation with transplant of whole organ	0.622	0.378
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.620	0.380
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.619	0.381
T65 Toxic effect of other and unspecified substances	0.618	0.382
T62 Toxic effect of other noxious substances eaten as food	0.618	0.382
T61 Toxic effect of noxious substances eaten as seafood	0.618	0.382
T60 Toxic effect of pesticides	0.618	0.382
T59 Toxic effect of other gases, fumes and vapours	0.618	0.382
T57 Toxic effect of other inorganic substances	0.618	0.382
T56 Toxic effect of metals	0.618	0.382
T54 Toxic effect of corrosive substances	0.618	0.382
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.618	0.382
T52 Toxic effect of organic solvents	0.618	0.382
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.618	0.382
T58 Toxic effect of carbon monoxide	0.618	0.382
T55 Toxic effect of soaps and detergents	0.618	0.382
F40-F48 Neurotic, stress-related and somatoform disorders	0.617	0.382
H53-H54 Visual disturbances and blindness	0.617	0.383
S68 Traumatic amputation of wrist and hand	0.615	0.385
S06.9 Intracranial injury, unspecified	0.615	0.385
S06.8 Other intracranial injuries	0.615	0.385
S06.7 Intracranial injury with prolonged coma	0.615	0.385
S06.4 Epidural haemorrhage	0.615	0.385
S06.3 Focal brain injury	0.615	0.385
S06.1 Traumatic cerebral oedema	0.615	0.385
S06.0 Concussion	0.615	0.385
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.615	0.385
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.614	0.386
F80-F89 Disorders of psychological development	0.614	0.386
F70-F79 Mental retardation	0.614	0.386
F60-F69 Disorders of adult personality and behaviour	0.614	0.386
S00.8 Superficial injury of other parts of head	0.613	0.387
F99-F99 Unspecified mental disorder	0.613	0.387
O66.0 Obstructed labour due to shoulder dystocia	0.612	0.388
W07 Fall involving chair	0.611	0.388
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.610	0.390
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.610	0.390
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.610	0.390
T46 Poisoning by agents primarily affecting the cardiovascular system	0.610	0.390
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.610	0.390
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.610	0.390
T41 Poisoning by anaesthetics and therapeutic gases	0.610	0.390
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.610	0.390
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.610	0.390
T36 Poisoning by systemic antibiotics	0.610	0.390
W18 Other fall on same level	0.610	0.390
W17 Other fall from one level to another	0.610	0.390
W16 Diving or jumping into water causing injury other than drowning or submersion	0.610	0.390
W15 Fall from cliff	0.610	0.390
W14 Fall from tree	0.610	0.390
W13 Fall from, out of or through building or structure	0.610	0.390
W12 Fall on and from scaffolding	0.610	0.390
W11 Fall on and from ladder	0.610	0.390
W09 Fall involving playground equipment	0.610	0.390
W08 Fall involving other furniture	0.610	0.390
W06 Fall involving bed	0.610	0.390
W05 Fall involving wheelchair	0.610	0.390
W04 Fall while being carried or supported by other persons	0.610	0.390
W03 Other fall on same level due to collision with, or pushing by, another person	0.610	0.390
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.610	0.390
W01 Fall on same level from slipping, tripping and stumbling	0.610	0.390
W00 Fall on same level involving ice and snow	0.610	0.390
O45 Premature separation of placenta [abruptio placentae]	0.609	0.391
O44 Placenta praevia	0.609	0.391
O43 Placental disorders	0.609	0.391
O35 Maternal care for known or suspected foetal abnormality and damage	0.609	0.391
O33 Maternal care for known or suspected disproportion	0.609	0.391
O31 Complications specific to multiple gestation	0.609	0.391
O40 Polyhydramnios	0.609	0.391
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.609	0.391
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.607	0.392
O34.2 Maternal care due to uterine scar from previous surgery	0.607	0.393
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.607	0.393
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.607	0.393
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.607	0.393
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.607	0.393
D80-D89 Certain disorders involving the immune mechanism	0.606	0.394
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.606	0.394
H65-H75 Diseases of middle ear and mastoid	0.605	0.395
O47 False labour	0.603	0.397
F38 Other mood [affective] disorders	0.602	0.398
F34 Persistent mood [affective] disorders	0.602	0.398
F30 Manic episode	0.602	0.398
F39 Unspecified mood [affective] disorder	0.602	0.398
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.600	0.400
O30 Multiple gestation	0.599	0.401
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.598	0.402
H90-H95 Other disorders of ear	0.597	0.403
S64.0 Injury of ulnar nerve at wrist and hand level	0.596	0.403
V18 Pedal cyclist injured in noncollision transport accident	0.596	0.404
F31.8 Other bipolar affective disorders	0.595	0.405
F31.7 Bipolar affective disorder, currently in remission	0.595	0.405
F31.6 Bipolar affective disorder, current episode mixed	0.595	0.405
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.595	0.405
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.588	0.412
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.587	0.413
S50 Superficial injury of forearm	0.587	0.413
O42 Premature rupture of membranes	0.587	0.413
Q00-Q07 Congenital malformations of the nervous system	0.585	0.415
Y84.9 Medical procedure, unspecified	0.585	0.415
Y84.7 Blood-sampling	0.585	0.415
Y84.5 Insertion of gastric or duodenal sound	0.585	0.415
Y84.4 Aspiration of fluid	0.585	0.415
Y84.3 Shock therapy	0.585	0.415
Y84.1 Kidney dialysis	0.585	0.415
T81.3 Disruption of operation wound, not elsewhere classified	0.584	0.416
S42.2 Fracture of upper end of humerus	0.584	0.416
O61.0 Failed medical induction of labour	0.583	0.417
S80.1 Contusion of other and unspecified parts of lower leg	0.581	0.419
S30 Superficial injury of abdomen, lower back and pelvis	0.580	0.420
W19.2 School, other institution and public administrative area	0.579	0.421
Q23 Congenital malformations of aortic and mitral valves	0.579	0.421
T43.5 Other and unspecified antipsychotics and neuroleptics	0.577	0.423
S32 Fracture of lumbar spine and pelvis	0.575	0.425
S42.30 Fracture of shaft of humerus (closed)	0.574	0.426
O63.9 Long labour, unspecified	0.573	0.427
O63.2 Delayed delivery of second twin, triplet, etc.	0.573	0.427
O80 Single spontaneous delivery	0.568	0.432
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.567	0.433
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.567	0.433
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.567	0.433
T84.3 Mechanical complication of other bone devices, implants and grafts	0.567	0.433
T84.2 Mechanical complication of internal fixation device of other bones	0.567	0.433
S80.9 Superficial injury of lower leg, unspecified	0.567	0.433
T19 Foreign body in genito-urinary tract	0.566	0.434
T18 Foreign body in alimentary tract	0.566	0.434
T15 Foreign body on external eye	0.566	0.434
T16 Foreign body in ear	0.566	0.434
S64.4 Injury of digital nerve of other finger	0.566	0.434
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.566	0.434
Q80-Q89 Other congenital malformations	0.566	0.434
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.566	0.434
Q60-Q64 Congenital malformations of the urinary system	0.566	0.434
Q50-Q56 Congenital malformations of genital organs	0.566	0.434
Q38-Q45 Other congenital malformations of the digestive system	0.566	0.434
Q35-Q37 Cleft lip and cleft palate	0.566	0.434
Q30-Q34 Congenital malformations of the respiratory system	0.566	0.434
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.566	0.434
W19.8 Other specified place	0.565	0.434
W19.5 Trade and service area	0.565	0.434
W19.0 Home	0.565	0.434
W19.7 Farm	0.565	0.434
W19.6 Industrial and construction area	0.565	0.434
W19.3 Sports and athletics area	0.565	0.434
W19.1 Residential institution	0.565	0.434
S49.8 Other specified injuries of shoulder and upper arm	0.563	0.437
S49.7 Multiple injuries of shoulder and upper arm	0.563	0.437
B25-B34 Other viral diseases	0.562	0.438
T98 Sequelae of other and unspecified effects of external causes	0.561	0.439
T95 Sequelae of burns, corrosions and frostbite	0.561	0.439
T94 Sequelae of injuries involving multiple and unspecified body regions	0.561	0.439
T92 Sequelae of injuries of upper limb	0.561	0.439
T90 Sequelae of injuries of head	0.561	0.439
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.561	0.439
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.561	0.439
S02.9 Fracture of skull and facial bones, part unspecified	0.558	0.441
S02.8 Fractures of other skull and facial bones	0.558	0.441
S02.7 Multiple fractures involving skull and facial bones	0.558	0.441
S02.6 Fracture of mandible	0.558	0.441
S02.3 Fracture of orbital floor	0.558	0.441
S02.0 Fracture of vault of skull	0.558	0.441
S06.20 Diffuse brain injury (without open intracranial wound)	0.558	0.442
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.557	0.443
S37 Injury of urinary and pelvic organs	0.557	0.443
S36 Injury of intra-abdominal organs	0.557	0.443
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.557	0.443
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.557	0.443
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.557	0.443
S31 Open wound of abdomen, lower back and pelvis	0.557	0.443
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.557	0.443
Y40 Systemic antibiotics	0.556	0.444
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.556	0.444
S66.8 Injury of other muscles and tendons at wrist and hand level	0.556	0.444
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.556	0.444
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.556	0.444
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.556	0.444
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.556	0.444
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.556	0.444
V17 Pedal cyclist injured in collision with fixed or stationary object	0.555	0.445
V16 Pedal cyclist injured in collision with other nonmotor vehicle	0.555	0.445
V15 Pedal cyclist injured in collision with railway train or railway vehicle	0.555	0.445
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus	0.555	0.445
V13 Pedal cyclist injured in collision with car, pick-up truck or van	0.555	0.445
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle	0.555	0.445
V11 Pedal cyclist injured in collision with other pedal cycle	0.555	0.445
V10 Pedal cyclist injured in collision with pedestrian or animal	0.555	0.445
S59 Other and unspecified injuries of forearm	0.555	0.445
S58 Traumatic amputation of forearm	0.555	0.445
S57 Crushing injury of forearm	0.555	0.445
S56 Injury of muscle and tendon at forearm level	0.555	0.445
S55 Injury of blood vessels at forearm level	0.555	0.445
S54 Injury of nerves at forearm level	0.555	0.445
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.555	0.445
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.553	0.446
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident	0.553	0.447
H53 Visual disturbances	0.553	0.447
S82.9 Fracture of lower leg, part unspecified	0.552	0.448
S82.7 Multiple fractures of lower leg	0.552	0.448
S82.0 Fracture of patella	0.552	0.448
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.552	0.448
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.551	0.449
S90 Superficial injury of ankle and foot	0.551	0.449
B35-B49 Mycoses	0.551	0.449
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.550	0.449
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.550	0.449
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.550	0.449
T83.3 Mechanical complication of intra-uterine contraceptive device	0.550	0.449
T83.2 Mechanical complication of graft of urinary organ	0.550	0.449
T83.1 Mechanical complication of other urinary devices and implants	0.550	0.449
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.550	0.449
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.550	0.450
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.550	0.450
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.550	0.450
S46.3 Injury of muscle and tendon of triceps	0.550	0.450
S46.2 Injury of muscle and tendon of other parts of biceps	0.550	0.450
S46.1 Injury of muscle and tendon of long head of biceps	0.550	0.450
O84 Multiple delivery	0.550	0.450
O83 Other assisted single delivery	0.550	0.450
O81 Single delivery by forceps and vacuum extractor	0.550	0.450
S81.8 Open wound of other parts of lower leg	0.549	0.450
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.549	0.451
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.549	0.451
H52 Disorders of refraction and accommodation	0.548	0.452
H61 Other disorders of external ear	0.548	0.452
O82.0 Delivery by elective Caesarean section	0.547	0.452
Y57 Other and unspecified drugs and medicaments	0.544	0.456
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.544	0.456
H40-H42 Glaucoma	0.544	0.456
Q21 Congenital malformations of cardiac septa	0.544	0.456
A30-A49 Other bacterial diseases	0.544	0.456
S82.4 Fracture of fibula alone	0.543	0.456
S02.4 Fracture of malar and maxillary bones	0.543	0.456
S61 Open wound of wrist and hand	0.543	0.457
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.543	0.457
S42.9 Fracture of shoulder girdle, part unspecified	0.542	0.457
S42.8 Fracture of other parts of shoulder and upper arm	0.542	0.457
S42.7 Multiple fractures of clavicle, scapula and humerus	0.542	0.457
S42.4 Fracture of lower end of humerus	0.542	0.457
S42.1 Fracture of scapula	0.542	0.457
H80-H83 Diseases of inner ear	0.542	0.457
T91.8 Sequelae of other specified injuries of neck and trunk	0.542	0.458
T85 Complications of other internal prosthetic devices, implants and grafts	0.541	0.458
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.540	0.459
T93 Sequelae of injuries of lower limb	0.538	0.461
D69 Purpura and other haemorrhagic conditions	0.538	0.462
T78 Adverse effects, not elsewhere classified	0.537	0.463
H43-H45 Disorders of vitreous body and globe	0.537	0.463
T17.9 Foreign body in respiratory tract, part unspecified	0.535	0.465
O32.9 Maternal care for malpresentation of foetus, unspecified	0.535	0.465
O32.8 Maternal care for other malpresentation of foetus	0.535	0.465
O32.6 Maternal care for compound presentation	0.535	0.465
O32.4 Maternal care for high head at term	0.535	0.465
O32.3 Maternal care for face, brow and chin presentation	0.535	0.465
O32.2 Maternal care for transverse and oblique lie	0.535	0.465
O32.0 Maternal care for unstable lie	0.535	0.465
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.534	0.466
T51.9 Alcohol, unspecified	0.533	0.467
T51.8 Other alcohols	0.533	0.467
T51.3 Fusel oil	0.533	0.467
T51.2 2-Propanol	0.533	0.467
T51.1 Methanol	0.533	0.467
S27 Injury of other and unspecified intrathoracic organs	0.531	0.469
H10-H13 Disorders of conjunctiva	0.531	0.469
T43.9 Psychotropic drug, unspecified	0.530	0.470
T43.8 Other psychotropic drugs, not elsewhere classified	0.530	0.470
T43.6 Psychostimulants with abuse potential	0.530	0.470
T43.4 Butyrophenone and thioxanthene neuroleptics	0.530	0.470
T43.3 Phenothiazine antipsychotics and neuroleptics	0.530	0.470
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.530	0.470
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.529	0.471
F00-F09 Organic, including symptomatic, mental disorders	0.529	0.471

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations