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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2021722
log Bayes Factor = 181.818
Chromosome 6   position 30,174,131  (GRCh37) Explore rs2021722 on Ensembl!
Variant rs2021722 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
D80-D89 Certain disorders involving the immune mechanism
0.998 0.002 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.998 0.002 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
L50-L54 Urticaria and erythema
0.998 0.002 0.000
K72 Hepatic failure, not elsewhere classified
0.997 0.003 0.000
E16 Other disorders of pancreatic internal secretion
0.997 0.003 0.000
K90-K93 Other diseases of the digestive system
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
D86 Sarcoidosis
0.996 0.004 0.000
E16.2 Hypoglycaemia, unspecified
0.996 0.004 0.000
C25 Malignant neoplasm of pancreas
0.995 0.005 0.000
E20-E35 Disorders of other endocrine glands
0.995 0.005 0.000
E10.3 With ophthalmic complications
0.995 0.005 0.000
D86.9 Sarcoidosis, unspecified
0.993 0.007 0.000
K75 Other inflammatory liver diseases
0.993 0.007 0.000
C18 Malignant neoplasm of colon
0.991 0.009 0.000
K72.0 Acute and subacute hepatic failure
0.990 0.010 0.000
K75.4 Autoimmune hepatitis
0.989 0.011 0.000
E27 Other disorders of adrenal gland
0.988 0.012 0.000
C25.9 Pancreas, unspecified
0.986 0.014 0.000
E14 Unspecified diabetes mellitus
0.983 0.017 0.000
Chapter I Certain infectious and parasitic diseases
0.982 0.018 0.000
E27.1 Primary adrenocortical insufficiency
0.981 0.019 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.981 0.019 0.000
M15-M19 Arthrosis
0.981 0.019 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.980 0.020 0.000
D69 Purpura and other haemorrhagic conditions
0.978 0.022 0.000
C18.4 Transverse colon
0.978 0.022 0.000
C85.1 B-cell lymphoma, unspecified
0.978 0.022 0.000
D60-D64 Aplastic and other anaemias
0.977 0.023 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.976 0.024 0.000
L50 Urticaria
0.975 0.025 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.972 0.028 0.000
E83.1 Disorders of iron metabolism
0.000 0.029 0.971
L97 Ulcer of lower limb, not elsewhere classified
0.969 0.031 0.000
D61 Other aplastic anaemias
0.968 0.032 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.968 0.032 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.967 0.033 0.000
M17 Gonarthrosis [arthrosis of knee]
0.967 0.033 0.000
I74 Arterial embolism and thrombosis
0.967 0.033 0.000
L52 Erythema nodosum
0.966 0.034 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.966 0.034 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.964 0.036 0.000
D69.6 Thrombocytopenia, unspecified
0.963 0.037 0.000
B35-B49 Mycoses
0.962 0.038 0.000
M18 Arthrosis of first carpometacarpal joint
0.962 0.038 0.000
D61.9 Aplastic anaemia, unspecified
0.960 0.040 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.959 0.041 0.000
Chapter IX Diseases of the circulatory system
0.959 0.041 0.000
C83.3 Large cell (diffuse)
0.959 0.041 0.000
B44 Aspergillosis
0.958 0.042 0.000
M17.1 Other primary gonarthrosis
0.956 0.044 0.000
E14.3 With ophthalmic complications
0.953 0.047 0.000
E10.2 With renal complications
0.952 0.048 0.000
C18.9 Colon, unspecified
0.948 0.052 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.942 0.058 0.000
L50.9 Urticaria, unspecified
0.938 0.062 0.000
J45.9 Asthma, unspecified
0.938 0.062 0.000
I77 Other disorders of arteries and arterioles
0.934 0.066 0.000
B44.9 Aspergillosis, unspecified
0.932 0.068 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.932 0.068 0.000
E10.1 With ketoacidosis
0.931 0.069 0.000
M86-M90 Other osteopathies
0.931 0.069 0.000
B02 Zoster [herpes zoster]
0.929 0.071 0.000
K76 Other diseases of liver
0.928 0.072 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.925 0.075 0.000
C18.7 Sigmoid colon
0.919 0.081 0.000
K73 Chronic hepatitis, not elsewhere classified
0.918 0.082 0.000
K72.9 Hepatic failure, unspecified
0.917 0.083 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.916 0.084 0.000
B44.1 Other pulmonary aspergillosis
0.911 0.089 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.911 0.089 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.909 0.091 0.000
C16 Malignant neoplasm of stomach
0.909 0.091 0.000
L53 Other erythematous conditions
0.908 0.092 0.000
I73 Other peripheral vascular diseases
0.908 0.092 0.000
C91 Lymphoid leukaemia
0.904 0.096 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.903 0.097 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.903 0.097 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.895 0.105 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.892 0.108 0.000
I77.1 Stricture of artery
0.891 0.109 0.000
B02.9 Zoster without complication
0.888 0.112 0.000
K76.9 Liver disease, unspecified
0.885 0.115 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.884 0.116 0.000
E10.4 With neurological complications
0.883 0.117 0.000
M40-M43 Deforming dorsopathies
0.881 0.119 0.000
C25.3 Pancreatic duct
0.879 0.121 0.000
I73.9 Peripheral vascular disease, unspecified
0.876 0.124 0.000
I10-I15 Hypertensive diseases
0.867 0.133 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.866 0.134 0.000
C04 Malignant neoplasm of floor of mouth
0.865 0.135 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.865 0.135 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.863 0.137 0.000
L20-L30 Dermatitis and eczema
0.859 0.141 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.859 0.141 0.000
K75.8 Other specified inflammatory liver diseases
0.856 0.144 0.000
D69.4 Other primary thrombocytopenia
0.854 0.146 0.000
L50.0 Allergic urticaria
0.853 0.147 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.853 0.147 0.000
E20 Hypoparathyroidism
0.851 0.149 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.849 0.151 0.000
M89 Other disorders of bone
0.846 0.154 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.846 0.154 0.000
C32 Malignant neoplasm of larynx
0.845 0.155 0.000
M86 Osteomyelitis
0.845 0.155 0.000
K76.6 Portal hypertension
0.845 0.155 0.000
E13 Other specified diabetes mellitus
0.839 0.161 0.000
L10-L14 Bullous disorders
0.838 0.162 0.000
E24 Cushing's syndrome
0.838 0.162 0.000
E21.3 Hyperparathyroidism, unspecified
0.837 0.163 0.000
M17.0 Primary gonarthrosis, bilateral
0.835 0.165 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.835 0.165 0.000
K73.9 Chronic hepatitis, unspecified
0.834 0.166 0.000
D80 Immunodeficiency with predominantly antibody defects
0.832 0.168 0.000
B08.1 Molluscum contagiosum
0.832 0.168 0.000
L53.9 Erythematous condition, unspecified
0.830 0.170 0.000
C95 Leukaemia of unspecified cell type
0.830 0.170 0.000
A80-A89 Viral infections of the central nervous system
0.828 0.172 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.828 0.172 0.000
E14.4 With neurological complications
0.828 0.172 0.000
L81 Other disorders of pigmentation
0.825 0.174 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.823 0.177 0.000
M80-M85 Disorders of bone density and structure
0.822 0.178 0.000
C88 Malignant immunoproliferative diseases
0.821 0.179 0.000
N40 Hyperplasia of prostate
0.000 0.181 0.819
D86.8 Sarcoidosis of other and combined sites
0.817 0.183 0.000
D64 Other anaemias
0.816 0.184 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.816 0.184 0.000
C18.6 Descending colon
0.815 0.185 0.000
M70-M79 Other soft tissue disorders
0.814 0.186 0.000
K72.1 Chronic hepatic failure
0.812 0.188 0.000
E05.8 Other thyrotoxicosis
0.811 0.188 0.000
L40-L45 Papulosquamous disorders
0.809 0.191 0.000
E14.8 With unspecified complications
0.809 0.191 0.000
E14.2 Withrenal complications
0.808 0.191 0.000
C02.9 Tongue, unspecified
0.808 0.192 0.000
I74.5 Embolism and thrombosis of iliac artery
0.808 0.192 0.000
E10.7 With multiple complications
0.807 0.193 0.000
E03.8 Other specified hypothyroidism
0.806 0.194 0.000
C91.1 Chronic lymphocytic leukaemia
0.806 0.194 0.000
M60-M63 Disorders of muscles
0.805 0.194 0.000
L81.9 Disorder of pigmentation, unspecified
0.804 0.196 0.000
C34 Malignant neoplasm of bronchus and lung
0.803 0.197 0.000
I12 Hypertensive renal disease
0.802 0.198 0.000
K76.7 Hepatorenal syndrome
0.800 0.200 0.000
C38.4 Pleura
0.799 0.201 0.000
D86.0 Sarcoidosis of lung
0.799 0.201 0.000
B01 Varicella [chickenpox]
0.798 0.202 0.000
B07 Viral warts
0.796 0.204 0.000
K90.9 Intestinal malabsorption, unspecified
0.795 0.205 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.794 0.206 0.000
M72 Fibroblastic disorders
0.794 0.206 0.000
M89.0 Algoneurodystrophy
0.793 0.207 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.793 0.207 0.000
L92.0 Granuloma annulare
0.791 0.209 0.000
D83 Common variable immunodeficiency
0.791 0.209 0.000
I11 Hypertensive heart disease
0.791 0.209 0.000
B02.2 Zoster with other nervous system involvement
0.789 0.211 0.000
B00 Herpesviral [herpes simplex] infections
0.788 0.212 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.786 0.214 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.785 0.215 0.000
C07 Malignant neoplasm of parotid gland
0.784 0.216 0.000
K90.8 Other intestinal malabsorption
0.784 0.216 0.000
C25.2 Tail of pancreas
0.782 0.218 0.000
C16.5 Lesser curvature of stomach, unspecified
0.780 0.220 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.779 0.221 0.000
E10.0 With coma
0.779 0.221 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.777 0.223 0.000
C84.5 Other and unspecified T-cell lymphomas
0.776 0.224 0.000
C10 Malignant neoplasm of oropharynx
0.773 0.227 0.000
D61.1 Drug-induced aplastic anaemia
0.773 0.227 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.772 0.228 0.000
D69.5 Secondary thrombocytopenia
0.771 0.229 0.000
L13 Other bullous disorders
0.771 0.229 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.770 0.230 0.000
E16.1 Other hypoglycaemia
0.769 0.230 0.000
M43 Other deforming dorsopathies
0.768 0.232 0.000
C25.8 Overlapping lesion of pancreas
0.768 0.232 0.000
C16.8 Overlapping lesion of stomach
0.767 0.233 0.000
Q50-Q56 Congenital malformations of genital organs
0.767 0.233 0.000
B44.8 Other forms of aspergillosis
0.766 0.234 0.000
E03.1 Congenital hypothyroidism without goitre
0.764 0.236 0.000
D69.0 Allergic purpura
0.762 0.238 0.000
M65-M68 Disorders of synovium and tendon
0.762 0.238 0.000
D69.9 Haemorrhagic condition, unspecified
0.761 0.238 0.000
E14.5 With peripheral circulatory complications
0.761 0.239 0.000
L94 Other localised connective tissue disorders
0.761 0.239 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.760 0.240 0.000
E24.2 Drug-induced Cushing's syndrome
0.759 0.241 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.759 0.241 0.000
C32.1 Supraglottis
0.759 0.241 0.000
E34 Other endocrine disorders
0.758 0.242 0.000
C16.2 Body of stomach
0.757 0.243 0.000
C13 Malignant neoplasm of hypopharynx
0.757 0.243 0.000
L30 Other dermatitis
0.757 0.243 0.000
A15-A19 Tuberculosis
0.756 0.243 0.000
C03 Malignant neoplasm of gum
0.755 0.245 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.755 0.245 0.000
C11 Malignant neoplasm of nasopharynx
0.753 0.246 0.000
M00-M03 Infectious arthropathies
0.752 0.248 0.000
M76 Enthesopathies of lower limb, excluding foot
0.751 0.249 0.000
M40 Kyphosis and lordosis
0.750 0.250 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.750 0.250 0.000
E20.9 Hypoparathyroidism, unspecified
0.748 0.252 0.000
D84 Other immunodeficiencies
0.748 0.252 0.000
C04.0 Anterior floor of mouth
0.747 0.253 0.000
C34.0 Main bronchus
0.745 0.255 0.000
E14.6 With other specified complications
0.744 0.256 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.742 0.258 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.742 0.258 0.000
M88 Paget's disease of bone [osteitis deformans]
0.741 0.259 0.000
E10.6 With other specified complications
0.741 0.259 0.000
C25.7 Other parts of pancreas
0.741 0.259 0.000
L50.1 Idiopathic urticaria
0.741 0.259 0.000
C18.8 Overlapping lesion of colon
0.738 0.262 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.738 0.262 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.738 0.262 0.000
D64.9 Anaemia, unspecified
0.736 0.264 0.000
C31 Malignant neoplasm of accessory sinuses
0.736 0.264 0.000
B99-B99 Other infectious diseases
0.735 0.265 0.000
C34.3 Lower lobe, bronchus or lung
0.734 0.266 0.000
L93 Lupus erythematosus
0.733 0.266 0.000
D69.2 Other nonthrombocytopenic purpura
0.733 0.267 0.000
C23 Malignant neoplasm of gallbladder
0.733 0.267 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.733 0.267 0.000
C84.0 Mycosis fungoides
0.732 0.267 0.000
L43 Lichen planus
0.730 0.270 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.729 0.270 0.000
E06 Thyroiditis
0.728 0.272 0.000
C05 Malignant neoplasm of palate
0.728 0.272 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.728 0.272 0.000
M85 Other disorders of bone density and structure
0.728 0.272 0.000
B49 Unspecified mycosis
0.727 0.273 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.726 0.274 0.000
C83.1 Small cleaved cell (diffuse)
0.726 0.274 0.000
B36 Other superficial mycoses
0.726 0.274 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.724 0.276 0.000
L13.0 Dermatitis herpetiformis
0.722 0.277 0.000
E23 Hypofunction and other disorders of pituitary gland
0.722 0.278 0.000
Q43 Other congenital malformations of intestine
0.721 0.279 0.000
Q00-Q07 Congenital malformations of the nervous system
0.720 0.280 0.000
L89 Decubitus ulcer
0.719 0.281 0.000
E10.5 With peripheral circulatory complications
0.718 0.282 0.000
E14.1 With ketoacidosis
0.718 0.282 0.000
C04.9 Floor of mouth, unspecified
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
C86 Other specified types of T/NK-cell lymphoma
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.717 0.283 0.000
D82 Immunodeficiency associated with other major defects
0.716 0.284 0.000
D81 Combined immunodeficiencies
0.716 0.284 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.716 0.284 0.000
C85.0 Lymphosarcoma
0.716 0.284 0.000
L54 Erythema in diseases classified elsewhere
0.715 0.285 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.715 0.285 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.715 0.285 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.715 0.285 0.000
E16.4 Abnormal secretion of gastrin
0.715 0.285 0.000
E16.3 Increased secretion of glucagon
0.715 0.285 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.715 0.285 0.000
E50-E64 Other nutritional deficiencies
0.715 0.285 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.714 0.286 0.000
C25.4 Endocrine pancreas
0.714 0.286 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.714 0.286 0.000
E32 Diseases of thymus
0.714 0.286 0.000
E31 Polyglandular dysfunction
0.714 0.286 0.000
E30 Disorders of puberty, not elsewhere classified
0.714 0.286 0.000
K75.2 Nonspecific reactive hepatitis
0.712 0.288 0.000
K75.1 Phlebitis of portal vein
0.712 0.288 0.000
M89.3 Hypertrophy of bone
0.711 0.289 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.711 0.289 0.000
C16.6 Greater curvature of stomach, unspecified
0.709 0.291 0.000
E13.9 Without complications
0.709 0.291 0.000
E27.5 Adrenomedullary hyperfunction
0.709 0.291 0.000
E27.0 Other adrenocortical overactivity
0.709 0.291 0.000
C93 Monocytic leukaemia
0.708 0.291 0.000
L30.9 Dermatitis, unspecified
0.709 0.291 0.000
C95.9 Leukaemia, unspecified
0.708 0.291 0.000
M89.07 Algoneurodystrophy (Ankle and foot)
0.708 0.292 0.000
B02.8 Zoster with other complications
0.706 0.294 0.000
E14.7 With multiple complications
0.705 0.295 0.000
E14.0 With coma
0.705 0.295 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.704 0.296 0.000
A75-A79 Rickettsioses
0.704 0.296 0.000
A70-A74 Other diseases caused by chlamydiae
0.704 0.296 0.000
A20-A28 Certain zoonotic bacterial diseases
0.704 0.296 0.000
D67 Hereditary factor IX deficiency
0.703 0.297 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.702 0.297 0.000
L23 Allergic contact dermatitis
0.702 0.298 0.000
I12.9 Hypertensive renal disease without renal failure
0.702 0.298 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.702 0.298 0.000
D69.8 Other specified haemorrhagic conditions
0.701 0.298 0.000
D69.1 Qualitative platelet defects
0.701 0.298 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.701 0.298 0.000
C09 Malignant neoplasm of tonsil
0.701 0.299 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.701 0.299 0.000
B06 Rubella [German measles]
0.700 0.300 0.000
B05 Measles
0.700 0.300 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.700 0.300 0.000
B04 Monkeypox
0.700 0.300 0.000
B03 Smallpox
0.700 0.300 0.000
D00-D09 In situ neoplasms
0.700 0.300 0.000
L50.6 Contact urticaria
0.699 0.301 0.000
L50.5 Cholinergic urticaria
0.699 0.301 0.000
L50.4 Vibratory urticaria
0.699 0.301 0.000
L50.3 Dermatographic urticaria
0.699 0.301 0.000
L50.2 Urticaria due to cold and heat
0.699 0.301 0.000
C83.6 Undifferentiated (diffuse)
0.697 0.303 0.000
C83.5 Lymphoblastic (diffuse)
0.697 0.303 0.000
C83.4 Immunoblastic (diffuse)
0.697 0.303 0.000
C83.2 Mixed small and large cell (diffuse)
0.697 0.303 0.000
K71 Toxic liver disease
0.697 0.303 0.000
M89.5 Osteolysis
0.696 0.304 0.000
M86.1 Other acute osteomyelitis
0.695 0.305 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.695 0.305 0.000
I12.0 Hypertensive renal disease with renal failure
0.695 0.305 0.000
L53.0 Toxic erythema
0.695 0.305 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.694 0.306 0.000
D61.8 Other specified aplastic anaemias
0.694 0.306 0.000
D61.3 Idiopathic aplastic anaemia
0.694 0.306 0.000
D61.2 Aplastic anaemia due to other external agents
0.694 0.306 0.000
M86.8 Other osteomyelitis
0.694 0.306 0.000
L20 Atopic dermatitis
0.694 0.306 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.694 0.306 0.000
L87 Transepidermal elimination disorders
0.694 0.306 0.000
L86 Keratoderma in diseases classified elsewhere
0.694 0.306 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.693 0.307 0.000
I27 Other pulmonary heart diseases
0.693 0.307 0.000
D61.0 Constitutional aplastic anaemia
0.692 0.307 0.000
C91.0 Acute lymphoblastic leukaemia
0.690 0.310 0.000
B48 Other mycoses, not elsewhere classified
0.690 0.310 0.000
B47 Mycetoma
0.690 0.310 0.000
B46 Zygomycosis
0.690 0.310 0.000
B45 Cryptococcosis
0.690 0.310 0.000
B43 Chromomycosis and phaeomycotic abscess
0.690 0.310 0.000
B42 Sporotrichosis
0.690 0.310 0.000
B41 Paracoccidioidomycosis
0.690 0.310 0.000
B40 Blastomycosis
0.690 0.310 0.000
B39 Histoplasmosis
0.690 0.310 0.000
B38 Coccidioidomycosis
0.690 0.310 0.000
I00-I02 Acute rheumatic fever
0.690 0.310 0.000
C91.9 Lymphoid leukaemia, unspecified
0.690 0.310 0.000
Q40 Other congenital malformations of upper alimentary tract
0.690 0.310 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.689 0.310 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.689 0.310 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.689 0.310 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.689 0.310 0.000
M67 Other disorders of synovium and tendon
0.689 0.311 0.000
C01 Malignant neoplasm of base of tongue
0.688 0.312 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.687 0.312 0.000
C33 Malignant neoplasm of trachea
0.687 0.312 0.000
B44.7 Disseminated aspergillosis
0.687 0.313 0.000
B44.2 Tonsillar aspergillosis
0.687 0.313 0.000
B44.0 Invasive pulmonary aspergillosis
0.687 0.313 0.000
M89.06 Algoneurodystrophy (Lower leg)
0.687 0.313 0.000
I74.8 Embolism and thrombosis of other arteries
0.687 0.313 0.000
C83.7 Burkitt's tumour
0.686 0.314 0.000
E10.8 With unspecified complications
0.686 0.314 0.000
Q44.5 Other congenital malformations of bile ducts
0.686 0.314 0.000
E25 Adrenogenital disorders
0.685 0.315 0.000
B25-B34 Other viral diseases
0.685 0.315 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.684 0.316 0.000
D86.3 Sarcoidosis of skin
0.684 0.316 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.684 0.316 0.000
Q44.6 Cystic disease of liver
0.684 0.316 0.000
C25.1 Body of pancreas
0.683 0.317 0.000
M76.6 Achilles tendinitis
0.683 0.317 0.000
M81 Osteoporosis without pathological fracture
0.683 0.317 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.682 0.317 0.000
B95-B98 Bacterial, viral and other infectious agents
0.682 0.318 0.000
C32.9 Larynx, unspecified
0.679 0.321 0.000
M40.2 Other and unspecified kyphosis
0.672 0.328 0.000
B01.9 Varicella without complications
0.670 0.330 0.000
I77.5 Necrosis of artery
0.669 0.330 0.000
I77.4 Coeliac artery compression syndrome
0.669 0.330 0.000
I77.3 Arterial fibromuscular dysplasia
0.669 0.330 0.000
C83.0 Small cell (diffuse)
0.669 0.331 0.000
C18.1 Appendix
0.668 0.332 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.667 0.333 0.000
L95.9 Vasculitis limited to skin, unspecified
0.666 0.334 0.000
B02.7 Disseminated zoster
0.666 0.334 0.000
B02.1 Zoster meningitis
0.666 0.334 0.000
B02.0 Zoster encephalitis
0.666 0.334 0.000
K76.5 Hepatic veno-occlusive disease
0.666 0.334 0.000
K76.4 Peliosis hepatis
0.666 0.334 0.000
K76.3 Infarction of liver
0.666 0.334 0.000
K76.2 Central haemorrhagic necrosis of liver
0.666 0.334 0.000
A65-A69 Other spirochaetal diseases
0.664 0.336 0.000
L42 Pityriasis rosea
0.664 0.336 0.000
K76.1 Chronic passive congestion of liver
0.664 0.336 0.000
M86.6 Other chronic osteomyelitis
0.660 0.340 0.000
C92 Myeloid leukaemia
0.660 0.340 0.000
M17.3 Other posttraumatic gonarthrosis
0.660 0.340 0.000
L43.9 Lichen planus, unspecified
0.660 0.340 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.658 0.342 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.658 0.342 0.000
E24.0 Pituitary-dependent Cushing's disease
0.658 0.342 0.000
Q54 Hypospadias
0.657 0.343 0.000
A87 Viral meningitis
0.657 0.343 0.000
L50.8 Other urticaria
0.656 0.344 0.000
C21 Malignant neoplasm of anus and anal canal
0.656 0.344 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.656 0.344 0.000
I77.6 Arteritis, unspecified
0.656 0.344 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.655 0.345 0.000
L27 Dermatitis due to substances taken internally
0.655 0.345 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.654 0.346 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.653 0.347 0.000
M96.5 Postradiation scoliosis
0.653 0.347 0.000
M96.4 Postsurgical lordosis
0.653 0.347 0.000
M96.3 Postlaminectomy kyphosis
0.653 0.347 0.000
M96.2 Postradiation kyphosis
0.653 0.347 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.653 0.347 0.000
L53.8 Other specified erythematous conditions
0.653 0.347 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.652 0.348 0.000
C16.4 Pylorus
0.652 0.348 0.000
C16.1 Fundus of stomach
0.652 0.348 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.651 0.349 0.000
L53.3 Other chronic figurate erythema
0.651 0.349 0.000
L53.2 Erythema marginatum
0.651 0.349 0.000
L53.1 Erythema annulare centrifugum
0.651 0.349 0.000
L88 Pyoderma gangrenosum
0.650 0.349 0.000
C91.4 Hairy-cell leukaemia
0.650 0.350 0.000
A86 Unspecified viral encephalitis
0.650 0.350 0.000
M15 Polyarthrosis
0.650 0.350 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.649 0.351 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.648 0.352 0.000
C91.7 Other lymphoid leukaemia
0.648 0.352 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.648 0.352 0.000
C91.5 Adult T-cell leukaemia
0.648 0.352 0.000
C91.3 Prolymphocytic leukaemia
0.648 0.352 0.000
C91.2 Subacute lymphocytic leukaemia
0.648 0.352 0.000
M99 Biomechanical lesions, not elsewhere classified
0.648 0.352 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.648 0.352 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.648 0.352 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.648 0.352 0.000
C84.3 Lymphoepithelioid lymphoma
0.648 0.352 0.000
C84.2 T-zone lymphoma
0.648 0.352 0.000
C84.1 Sezary's diease
0.648 0.352 0.000
Q35-Q37 Cleft lip and cleft palate
0.647 0.353 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.647 0.353 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.644 0.356 0.000
C17 Malignant neoplasm of small intestine
0.644 0.356 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.644 0.356 0.000
M86.9 Osteomyelitis, unspecified
0.643 0.356 0.000
I15 Secondary hypertension
0.643 0.357 0.000
B00.5 Herpesviral ocular disease
0.642 0.357 0.000
D83.9 Common variable immunodeficiency, unspecified
0.642 0.358 0.000
D04 Carcinoma in situ of skin
0.642 0.358 0.000
E21.4 Other specified disorders of parathyroid gland
0.642 0.358 0.000
E21.2 Other hyperparathyroidism
0.642 0.358 0.000
Q80-Q89 Other congenital malformations
0.641 0.358 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.641 0.359 0.000
B08.8 Other specified viral infections characterised by skin and mucous membrane lesions
0.640 0.360 0.000
B08.5 Enteroviral vesicular pharyngitis
0.640 0.360 0.000
B08.4 Enteroviral vesicular stomatitis with exanthem
0.640 0.360 0.000
B08.3 Erythema infectiosum [fifth disease]
0.640 0.360 0.000
B08.2 Exanthema subitum [sixth disease]
0.640 0.360 0.000
B08.0 Other orthopoxvirus infections
0.640 0.360 0.000
E40-E46 Malnutrition
0.640 0.360 0.000
M67.8 Other specified disorders of synovium and tendon
0.639 0.361 0.000
M43.1 Spondylolisthesis
0.638 0.362 0.000
C16.0 Cardia
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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