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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs204999
log Bayes Factor = 225.279
Chromosome 6   position 32,109,979  (GRCh37) Explore rs204999 on Ensembl!
Variant rs204999 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.999 0.001 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.001 0.999
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.999 0.001 0.000
R31 Unspecified haematuria
0.000 0.001 0.999
# Top node
0.999 0.001 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
K90 Intestinal malabsorption
0.999 0.001 0.000
E11 Non-insulin-dependent diabetes mellitus
0.998 0.002 0.000
E10.1 With ketoacidosis
0.998 0.002 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.998 0.002 0.000
L40.5 Arthropathic psoriasis
0.997 0.003 0.000
E14.3 With ophthalmic complications
0.996 0.004 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.005 0.995
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.995 0.005 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.005 0.995
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.994 0.006 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.007 0.993
M05-M14 Inflammatory polyarthropathies
0.000 0.008 0.992
N00-N08 Glomerular diseases
0.992 0.008 0.000
N04 Nephrotic syndrome
0.991 0.009 0.000
D64.9 Anaemia, unspecified
0.988 0.012 0.000
D60-D64 Aplastic and other anaemias
0.988 0.012 0.000
N04.9 Unspecified
0.987 0.013 0.000
D64 Other anaemias
0.987 0.013 0.000
E11.9 Without complications
0.987 0.013 0.000
N05 Unspecified nephritic syndrome
0.983 0.017 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.980 0.020 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.978 0.022 0.000
K51 Ulcerative colitis
0.000 0.024 0.976
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.025 0.975
Chapter II Neoplasms
0.974 0.026 0.000
C15-C26 Malignant neoplasms of digestive organs
0.971 0.029 0.000
N05.2 Diffuse membranous glomerulonephritis
0.970 0.030 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.970 0.030 0.000
K90.9 Intestinal malabsorption, unspecified
0.970 0.030 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.965 0.035 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.038 0.962
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.039 0.961
K90-K93 Other diseases of the digestive system
0.959 0.041 0.000
Chapter XI Diseases of the digestive system
0.955 0.045 0.000
Q50-Q56 Congenital malformations of genital organs
0.955 0.045 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.045 0.955
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.045 0.955
M06.3 Rheumatoid nodule
0.000 0.046 0.954
K70-K77 Diseases of liver
0.951 0.049 0.000
E14.9 Without complications
0.949 0.051 0.000
L10-L14 Bullous disorders
0.948 0.052 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.946 0.054 0.000
C85.1 B-cell lymphoma, unspecified
0.942 0.058 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.941 0.059 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.939 0.061 0.000
K75 Other inflammatory liver diseases
0.939 0.061 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.063 0.937
C83.3 Large cell (diffuse)
0.937 0.063 0.000
C91 Lymphoid leukaemia
0.935 0.065 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.934 0.066 0.000
C20 Malignant neoplasm of rectum
0.932 0.068 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.932 0.068 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.071 0.929
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.927 0.073 0.000
L13 Other bullous disorders
0.925 0.075 0.000
K75.8 Other specified inflammatory liver diseases
0.923 0.077 0.000
D70 Agranulocytosis
0.922 0.078 0.000
L50-L54 Urticaria and erythema
0.921 0.079 0.000
E20-E35 Disorders of other endocrine glands
0.921 0.079 0.000
C15 Malignant neoplasm of oesophagus
0.917 0.083 0.000
E10.4 With neurological complications
0.916 0.084 0.000
E10.2 With renal complications
0.916 0.084 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.912 0.088 0.000
M45 Ankylosing spondylitis
0.000 0.089 0.911
C34 Malignant neoplasm of bronchus and lung
0.911 0.089 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.911 0.089 0.000
L13.0 Dermatitis herpetiformis
0.909 0.091 0.000
K51.4 Pseudopolyposis of colon
0.000 0.091 0.909
E16.0 Drug-induced hypoglycaemia without coma
0.908 0.092 0.000
Chapter XIV Diseases of the genitourinary system
0.908 0.092 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.092 0.908
E13 Other specified diabetes mellitus
0.907 0.093 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.905 0.095 0.000
E11.3 With ophthalmic complications
0.904 0.096 0.000
E11.6 With other specified complications
0.902 0.098 0.000
Q60-Q64 Congenital malformations of the urinary system
0.899 0.101 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.899 0.101 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.898 0.102 0.000
C91.1 Chronic lymphocytic leukaemia
0.895 0.105 0.000
C34.3 Lower lobe, bronchus or lung
0.893 0.107 0.000
E14.8 With unspecified complications
0.890 0.109 0.000
K73 Chronic hepatitis, not elsewhere classified
0.881 0.119 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.123 0.877
N17-N19 Renal failure
0.876 0.124 0.000
L52 Erythema nodosum
0.873 0.127 0.000
K75.4 Autoimmune hepatitis
0.873 0.127 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.872 0.128 0.000
N18 Chronic renal failure
0.871 0.129 0.000
L40.0 Psoriasis vulgaris
0.871 0.129 0.000
C15.4 Middle third of oesophagus
0.867 0.133 0.000
C23 Malignant neoplasm of gallbladder
0.867 0.133 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.863 0.137 0.000
G56.0 Carpal tunnel syndrome
0.863 0.137 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.861 0.139 0.000
C21 Malignant neoplasm of anus and anal canal
0.861 0.139 0.000
G56 Mononeuropathies of upper limb
0.860 0.140 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.859 0.141 0.000
E11.2 With renal complications
0.858 0.142 0.000
E11.1 With ketoacidosis
0.857 0.143 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.856 0.144 0.000
Chapter VI Diseases of the nervous system
0.854 0.146 0.000
L44 Other papulosquamous disorders
0.852 0.148 0.000
N18.9 Chronic renal failure, unspecified
0.852 0.148 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.851 0.149 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.847 0.153 0.000
E13.9 Without complications
0.846 0.154 0.000
E14.4 With neurological complications
0.844 0.156 0.000
L40.1 Generalised pustular psoriasis
0.842 0.158 0.000
Q54 Hypospadias
0.840 0.160 0.000
C95 Leukaemia of unspecified cell type
0.840 0.160 0.000
K51.8 Other ulcerative colitis
0.000 0.161 0.839
E16.1 Other hypoglycaemia
0.835 0.165 0.000
C22.9 Liver, unspecified
0.832 0.168 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.173 0.827
N18.4 Chronic kidney disease, stage 4
0.825 0.175 0.000
E24 Cushing's syndrome
0.822 0.178 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.821 0.179 0.000
N05.1 Focal and segmental glomerular lesions
0.821 0.179 0.000
N04.2 Diffuse membranous glomerulonephritis
0.820 0.180 0.000
E03.8 Other specified hypothyroidism
0.818 0.182 0.000
G51 Facial nerve disorders
0.816 0.184 0.000
C91.0 Acute lymphoblastic leukaemia
0.815 0.185 0.000
L40.3 Pustulosis palmaris et plantaris
0.814 0.186 0.000
C22.1 Intrahepatic bile duct carcinoma
0.810 0.190 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.190 0.810
Q80-Q89 Other congenital malformations
0.808 0.192 0.000
E10.8 With unspecified complications
0.806 0.194 0.000
Q00-Q07 Congenital malformations of the nervous system
0.805 0.195 0.000
E21.3 Hyperparathyroidism, unspecified
0.803 0.197 0.000
Q61 Cystic kidney disease
0.801 0.199 0.000
E14.1 With ketoacidosis
0.799 0.201 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.201 0.798
C34.2 Middle lobe, bronchus or lung
0.798 0.202 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.796 0.204 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.204 0.796
N04.1 Focal and segmental glomerular lesions
0.792 0.207 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.792 0.208 0.000
N05.8 Other
0.792 0.208 0.000
N04.0 Minor glomerular abnormality
0.791 0.208 0.000
E03.1 Congenital hypothyroidism without goitre
0.788 0.212 0.000
E14.2 Withrenal complications
0.783 0.216 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.782 0.217 0.000
D55-D59 Haemolytic anaemias
0.781 0.219 0.000
K74 Fibrosis and cirrhosis of liver
0.780 0.220 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.779 0.221 0.000
E10.0 With coma
0.778 0.222 0.000
K72 Hepatic failure, not elsewhere classified
0.778 0.222 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.223 0.777
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.776 0.224 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.226 0.774
C22.0 Liver cell carcinoma
0.769 0.231 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.768 0.232 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.765 0.235 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.762 0.238 0.000
C38.4 Pleura
0.760 0.240 0.000
E10.7 With multiple complications
0.760 0.240 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.759 0.241 0.000
C82.2 Large cell, follicular
0.758 0.242 0.000
E14.5 With peripheral circulatory complications
0.754 0.246 0.000
Q78 Other osteochondrodysplasias
0.753 0.247 0.000
E27 Other disorders of adrenal gland
0.753 0.247 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.753 0.247 0.000
K90.8 Other intestinal malabsorption
0.751 0.249 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.249 0.751
M12 Other specific arthropathies
0.000 0.250 0.750
G51.9 Disorder of facial nerve, unspecified
0.749 0.251 0.000
L42 Pityriasis rosea
0.748 0.252 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.748 0.252 0.000
L53 Other erythematous conditions
0.747 0.252 0.000
L44.0 Pityriasis rubra pilaris
0.746 0.254 0.000
C34.8 Overlapping lesion of bronchus and lung
0.745 0.255 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.255 0.745
Q52 Other congenital malformations of female genitalia
0.742 0.258 0.000
K51.5 Mucosal proctocolitis
0.000 0.258 0.742
G51.0 Bell's palsy
0.741 0.259 0.000
C91.9 Lymphoid leukaemia, unspecified
0.741 0.259 0.000
C95.9 Leukaemia, unspecified
0.741 0.259 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.740 0.260 0.000
E07 Other disorders of thyroid
0.739 0.261 0.000
K50-K52 Noninfective enteritis and colitis
0.374 0.263 0.363
E24.0 Pituitary-dependent Cushing's disease
0.737 0.263 0.000
E27.1 Primary adrenocortical insufficiency
0.733 0.267 0.000
E10.6 With other specified complications
0.733 0.267 0.000
Q54.1 Hypospadias, penile
0.732 0.268 0.000
Q51 Congenital malformations of uterus and cervix
0.732 0.268 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.732 0.268 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.268 0.732
C21.0 Anus, unspecified
0.729 0.271 0.000
C31 Malignant neoplasm of accessory sinuses
0.729 0.271 0.000
N18.0 End-stage renal disease
0.727 0.273 0.000
Q74 Other congenital malformations of limb(s)
0.722 0.278 0.000
C15.0 Cervical part of oesophagus
0.722 0.278 0.000
K74.0 Hepatic fibrosis
0.722 0.278 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.721 0.279 0.000
K73.9 Chronic hepatitis, unspecified
0.721 0.279 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.720 0.279 0.000
Q61.2 Polycystic kidney, adult type
0.718 0.282 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
Q85 Phakomatoses, not elsewhere classified
0.717 0.283 0.000
L41 Parapsoriasis
0.716 0.284 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.716 0.284 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.284 0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.284 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.284 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.716 0.284 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.716 0.284 0.000
K90.1 Tropical sprue
0.716 0.284 0.000
E11.7 With multiple complications
0.716 0.284 0.000
N18.2 Chronic kidney disease, stage 2
0.716 0.284 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.286 0.714
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.286 0.714
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.286 0.714
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.286 0.714
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.286 0.714
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.286 0.714
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.286 0.714
D80-D89 Certain disorders involving the immune mechanism
0.714 0.286 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.287 0.713
M05.2 Rheumatoid vasculitis
0.000 0.287 0.713
M05.1 Rheumatoid lung disease
0.000 0.287 0.713
M05.0 Felty's syndrome
0.000 0.287 0.713
Q68 Other congenital musculoskeletal deformities
0.713 0.287 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.712 0.288 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.288 0.711
N07 Hereditary nephropathy, not elsewhere classified
0.711 0.289 0.000
N06 Isolated proteinuria with specified morphological lesion
0.711 0.289 0.000
N01 Rapidly progressive nephritic syndrome
0.711 0.289 0.000
N00 Acute nephritic syndrome
0.711 0.289 0.000
N04.8 Other
0.710 0.289 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.710 0.289 0.000
N04.6 Dense deposit disease
0.710 0.289 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.710 0.289 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.710 0.289 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.710 0.289 0.000
Q76 Congenital malformations of spine and bony thorax
0.709 0.291 0.000
C15.1 Thoracic part of oesophagus
0.709 0.291 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.708 0.292 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.708 0.292 0.000
D64.4 Congenital dyserythropoietic anaemia
0.708 0.292 0.000
D64.3 Other sideroblastic anaemias
0.708 0.292 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.708 0.292 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.708 0.292 0.000
D64.0 Hereditary sideroblastic anaemia
0.708 0.292 0.000
L43 Lichen planus
0.706 0.294 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.295 0.705
N05.6 Dense deposit disease
0.705 0.295 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.705 0.295 0.000
N05.0 Minor glomerular abnormality
0.705 0.295 0.000
E31 Polyglandular dysfunction
0.705 0.295 0.000
D73 Diseases of spleen
0.704 0.296 0.000
Q55 Other congenital malformations of male genital organs
0.703 0.297 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.703 0.297 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.703 0.297 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.703 0.297 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.703 0.297 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.703 0.297 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.298 0.702
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.701 0.298 0.000
C94 Other leukaemias of specified cell type
0.701 0.298 0.000
M20.1 Hallux valgus (acquired)
0.000 0.299 0.701
C45 Mesothelioma
0.701 0.299 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.699 0.301 0.000
L11 Other acantholytic disorders
0.699 0.301 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.699 0.301 0.000
Q38.1 Ankyloglossia
0.697 0.303 0.000
C34.0 Main bronchus
0.696 0.304 0.000
G56.4 Causalgia
0.696 0.304 0.000
C33 Malignant neoplasm of trachea
0.695 0.305 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.305 0.695
C85.0 Lymphosarcoma
0.692 0.308 0.000
C38.3 Mediastinum, part unspecified
0.692 0.308 0.000
Q44.6 Cystic disease of liver
0.688 0.312 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.688 0.312 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.687 0.312 0.000
C86 Other specified types of T/NK-cell lymphoma
0.687 0.313 0.000
K74.6 Other and unspecified cirrhosis of liver
0.686 0.314 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.685 0.315 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.685 0.315 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.685 0.315 0.000
Q50.5 Embryonic cyst of broad ligament
0.685 0.315 0.000
M35.3 Polymyalgia rheumatica
0.000 0.315 0.685
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.316 0.684
M06.38 Rheumatoid nodule (Other)
0.000 0.316 0.684
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.316 0.684
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.316 0.684
M06.33 Rheumatoid nodule (Forearm)
0.000 0.316 0.684
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.316 0.684
Q40 Other congenital malformations of upper alimentary tract
0.684 0.316 0.000
M20 Acquired deformities of fingers and toes
0.000 0.316 0.684
Q54.9 Hypospadias, unspecified
0.682 0.317 0.000
Q89 Other congenital malformations, not elsewhere classified
0.682 0.318 0.000
K77 Liver disorders in diseases classified elsewhere
0.682 0.318 0.000
E11.5 With peripheral circulatory complications
0.682 0.318 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.319 0.680
Q35-Q37 Cleft lip and cleft palate
0.680 0.320 0.000
L10 Pemphigus
0.680 0.320 0.000
L14 Bullous disorders in diseases classified elsewhere
0.680 0.320 0.000
E28 Ovarian dysfunction
0.679 0.321 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.321 0.678
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.678 0.322 0.000
C83.6 Undifferentiated (diffuse)
0.675 0.325 0.000
C83.5 Lymphoblastic (diffuse)
0.675 0.325 0.000
C83.4 Immunoblastic (diffuse)
0.675 0.325 0.000
C83.2 Mixed small and large cell (diffuse)
0.675 0.325 0.000
E21.2 Other hyperparathyroidism
0.674 0.326 0.000
C37 Malignant neoplasm of thymus
0.674 0.326 0.000
C82.6 Cutaneous follicle centre lymphoma
0.673 0.326 0.000
C82.5 Diffuse follicle centre lymphoma
0.673 0.326 0.000
C82.4 Follicular lymphoma grade IIIb
0.673 0.326 0.000
K75.2 Nonspecific reactive hepatitis
0.673 0.327 0.000
K75.1 Phlebitis of portal vein
0.673 0.327 0.000
M45-M49 Spondylopathies
0.002 0.327 0.671
G59 Mononeuropathy in diseases classified elsewhere
0.672 0.328 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.328 0.672
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.008 0.328 0.664
C91.8 Mature B-cell leukaemia Burkitt-type
0.670 0.330 0.000
C91.7 Other lymphoid leukaemia
0.670 0.330 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.670 0.330 0.000
C91.3 Prolymphocytic leukaemia
0.670 0.330 0.000
C91.2 Subacute lymphocytic leukaemia
0.670 0.330 0.000
E24.2 Drug-induced Cushing's syndrome
0.670 0.330 0.000
D74 Methaemoglobinaemia
0.670 0.330 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.670 0.330 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.670 0.330 0.000
E11.4 With neurological complications
0.670 0.330 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.669 0.331 0.000
C22.7 Other specified carcinomas of liver
0.668 0.332 0.000
C22.4 Other sarcomas of liver
0.668 0.332 0.000
C22.3 Angiosarcoma of liver
0.668 0.332 0.000
C22.2 Hepatoblastoma
0.668 0.332 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.668 0.332 0.000
M35 Other systemic involvement of connective tissue
0.000 0.333 0.667
D59 Acquired haemolytic anaemia
0.667 0.333 0.000
M08 Juvenile arthritis
0.001 0.334 0.666
C40-C41 Malignant neoplasms of bone and articular cartilage
0.665 0.335 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.664 0.336 0.000
G50 Disorders of trigeminal nerve
0.664 0.336 0.000
L13.9 Bullous disorder, unspecified
0.663 0.336 0.000
L13.8 Other specified bullous disorders
0.663 0.336 0.000
L13.1 Subcorneal pustular dermatitis
0.663 0.336 0.000
M20-M25 Other joint disorders
0.000 0.337 0.663
N03 Chronic nephritic syndrome
0.662 0.338 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.339 0.661
L54 Erythema in diseases classified elsewhere
0.661 0.339 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.660 0.339 0.000
E32 Diseases of thymus
0.660 0.339 0.000
E30 Disorders of puberty, not elsewhere classified
0.660 0.339 0.000
E25 Adrenogenital disorders
0.660 0.339 0.000
Q61.3 Polycystic kidney, unspecified
0.660 0.340 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.659 0.341 0.000
D80 Immunodeficiency with predominantly antibody defects
0.659 0.341 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.658 0.342 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.658 0.342 0.000
C15.8 Overlapping lesion of oesophagus
0.658 0.342 0.000
C15.2 Abdominal part of oesophagus
0.658 0.342 0.000
C21.1 Anal canal
0.657 0.343 0.000
C15.9 Oesophagus, unspecified
0.656 0.344 0.000
E40-E46 Malnutrition
0.655 0.345 0.000
Q43 Other congenital malformations of intestine
0.655 0.345 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.654 0.346 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.654 0.346 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.346 0.653
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.346 0.653
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.346 0.653
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.346 0.653
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.346 0.653
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.346 0.653
N18.1 Chronic kidney disease, stage 1
0.653 0.347 0.000
Q75 Other congenital malformations of skull and face bones
0.653 0.347 0.000
Q73 Reduction defects of unspecified limb
0.653 0.347 0.000
Q72 Reduction defects of lower limb
0.653 0.347 0.000
Q71 Reduction defects of upper limb
0.653 0.347 0.000
Q70 Syndactyly
0.653 0.347 0.000
Q69 Polydactyly
0.653 0.347 0.000
C15.5 Lower third of oesophagus
0.652 0.348 0.000
Q03 Congenital hydrocephalus
0.651 0.349 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.651 0.349 0.000
E13.8 With unspecified complications
0.650 0.349 0.000
E13.7 With multiple complications
0.650 0.349 0.000
E13.6 With other specified complications
0.650 0.349 0.000
E13.5 With peripheral circulatory complications
0.650 0.349 0.000
E13.4 With neurological complications
0.650 0.349 0.000
E13.2 With renal complications
0.650 0.349 0.000
E13.1 With ketoacidosis
0.650 0.349 0.000
E13.0 With coma
0.650 0.349 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.648 0.352 0.000
Q53 Undescended testicle
0.648 0.352 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.648 0.352 0.000
C60-C63 Malignant neoplasms of male genital organs
0.647 0.352 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.643 0.357 0.000
Q64 Other congenital malformations of urinary system
0.641 0.359 0.000
Q78.0 Osteogenesis imperfecta
0.641 0.359 0.000
C83.7 Burkitt's tumour
0.640 0.360 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.361 0.639
L50 Urticaria
0.639 0.361 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.638 0.362 0.000
Q63 Other congenital malformations of kidney
0.638 0.362 0.000
G56.1 Other lesions of median nerve
0.638 0.362 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.637 0.363 0.000
E20 Hypoparathyroidism
0.634 0.365 0.000
G00 Bacterial meningitis, not elsewhere classified
0.634 0.366 0.000
L53.9 Erythematous condition, unspecified
0.634 0.366 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.633 0.367 0.000
C82.0 Small cleaved cell, follicular
0.632 0.368 0.000
C45.0 Mesothelioma of pleura
0.632 0.368 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.368 0.632
L40.8 Other psoriasis
0.631 0.368 0.000
D50-D53 Nutritional anaemias
0.632 0.368 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.631 0.368 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.631 0.368 0.000
Q45 Other congenital malformations of digestive system
0.631 0.369 0.000
E13.3 With ophthalmic complications
0.630 0.370 0.000
K72.1 Chronic hepatic failure
0.630 0.370 0.000
K71 Toxic liver disease
0.629 0.371 0.000
D73.5 Infarction of spleen
0.629 0.371 0.000
C93 Monocytic leukaemia
0.628 0.372 0.000
Chapter XXII Codes for special purposes
0.627 0.373 0.000
E23 Hypofunction and other disorders of pituitary gland
0.627 0.373 0.000
K72.0 Acute and subacute hepatic failure
0.626 0.374 0.000
E21.4 Other specified disorders of parathyroid gland
0.625 0.375 0.000
Q79.6 Ehlers-Danlos syndrome
0.625 0.375 0.000
Q65 Congenital deformities of hip
0.624 0.376 0.000
Q44.5 Other congenital malformations of bile ducts
0.623 0.377 0.000
Q54.8 Other hypospadias
0.622 0.377 0.000
Q04 Other congenital malformations of brain
0.622 0.378 0.000
M20.3 Other deformity of hallux (acquired)
0.000 0.378 0.622
E21.0 Primary hyperparathyroidism
0.620 0.379 0.000
G70-G73 Diseases of myoneural junction and muscle
0.619 0.381 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.618 0.382 0.000
N18.8 Other chronic renal failure
0.618 0.382 0.000
C21.2 Cloacogenic zone
0.617 0.383 0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament
0.616 0.384 0.000
Q50.3 Other congenital malformations of ovary
0.616 0.384 0.000
Q50.2 Congenital torsion of ovary
0.616 0.384 0.000
Q50.1 Developmental ovarian cyst
0.616 0.384 0.000
Q50.0 Congenital absence of ovary
0.616 0.384 0.000
E34 Other endocrine disorders
0.614 0.386 0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura
0.614 0.386 0.000
C38.2 Posterior mediastinum
0.614 0.386 0.000
C38.1 Anterior mediastinum
0.614 0.386 0.000
C38.0 Heart
0.614 0.386 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.613 0.387 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.613 0.387 0.000
Q61.0 Congenital single renal cyst
0.612 0.388 0.000
Q39 Congenital malformations of oesophagus
0.611 0.388 0.000
L44.9 Papulosquamous disorder, unspecified
0.611 0.389 0.000
L44.8 Other specified papulosquamous disorders
0.611 0.389 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.611 0.389 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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