TreeWAS – Variant ID: rs2071554

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	0.999	0.001	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.999	0.001	0.000
E10-E14 Diabetes mellitus	0.998	0.002	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.997	0.003	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.993	0.007	0.000
E10.1 With ketoacidosis	0.990	0.010	0.000
E11 Non-insulin-dependent diabetes mellitus	0.980	0.020	0.000
H36.0 Diabetic retinopathy	0.973	0.027	0.000
E10.4 With neurological complications	0.970	0.030	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.968	0.032	0.000
M70-M79 Other soft tissue disorders	0.960	0.040	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.951	0.049	0.000
E11.9 Without complications	0.944	0.056	0.000
E16 Other disorders of pancreatic internal secretion	0.938	0.062	0.000
E10.5 With peripheral circulatory complications	0.937	0.063	0.000
H36 Retinal disorders in diseases classified elsewhere	0.937	0.063	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.933	0.067	0.000
E11.3 With ophthalmic complications	0.930	0.070	0.000
E16.2 Hypoglycaemia, unspecified	0.929	0.071	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.916	0.084	0.000
H30-H36 Disorders of choroid and retina	0.911	0.089	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.906	0.094	0.000
# Top node	0.906	0.094	0.000
Chapter VII Diseases of the eye and adnexa	0.905	0.095	0.000
K90.0 Coeliac disease	0.000	0.099	0.901
M06.0 Seronegative rheumatoid arthritis	0.893	0.107	0.000
M06.3 Rheumatoid nodule	0.885	0.115	0.000
F41 Other anxiety disorders	0.879	0.121	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.869	0.131	0.000
Chapter V Mental and behavioural disorders	0.867	0.133	0.000
F41.2 Mixed anxiety and depressive disorder	0.867	0.133	0.000
E10.2 With renal complications	0.862	0.138	0.000
F41.9 Anxiety disorder, unspecified	0.855	0.145	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.854	0.146	0.000
M79.1 Myalgia	0.850	0.150	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.838	0.162	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.837	0.163	0.000
M79.0 Rheumatism, unspecified	0.837	0.163	0.000
M80-M85 Disorders of bone density and structure	0.835	0.165	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.835	0.165	0.000
M20-M25 Other joint disorders	0.834	0.166	0.000
E14 Unspecified diabetes mellitus	0.818	0.182	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.815	0.185	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.815	0.185	0.000
M06.4 Inflammatory polyarthropathy	0.811	0.189	0.000
M25 Other joint disorders, not elsewhere classified	0.811	0.189	0.000
M06.34 Rheumatoid nodule (Hand)	0.802	0.198	0.000
M45-M49 Spondylopathies	0.801	0.199	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.798	0.202	0.000
M07 Psoriatic and enteropathic arthropathies	0.792	0.208	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.791	0.209	0.000
E20-E35 Disorders of other endocrine glands	0.788	0.212	0.000
M86-M90 Other osteopathies	0.780	0.220	0.000
M79.18 Myalgia (Other)	0.779	0.221	0.000
M77 Other enthesopathies	0.777	0.223	0.000
M75 Shoulder lesions	0.776	0.224	0.000
M60-M63 Disorders of muscles	0.771	0.229	0.000
M25.5 Pain in joint	0.762	0.238	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.757	0.243	0.000
E14.3 With ophthalmic complications	0.752	0.248	0.000
M79.5 Residual foreign body in soft tissue	0.742	0.258	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.741	0.259	0.000
M91-M94 Chondropathies	0.738	0.261	0.000
M72 Fibroblastic disorders	0.738	0.262	0.000
M79.10 Myalgia (Multiple sites)	0.729	0.271	0.000
E11.2 With renal complications	0.728	0.272	0.000
M80 Osteoporosis with pathological fracture	0.727	0.273	0.000
H30 Chorioretinal inflammation	0.727	0.273	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.723	0.277	0.000
H17 Corneal scars and opacities	0.722	0.278	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.719	0.281	0.000
M79.2 Neuralgia and neuritis, unspecified	0.717	0.282	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
E10.8 With unspecified complications	0.717	0.283	0.000
E10.7 With multiple complications	0.717	0.283	0.000
E10.6 With other specified complications	0.717	0.283	0.000
E10.0 With coma	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M14 Arthropathies in other diseases classified elsewhere	0.717	0.283	0.000
M12 Other specific arthropathies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
M05.8 Other seropositive rheumatoid arthritis	0.716	0.284	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.716	0.284	0.000
M05.2 Rheumatoid vasculitis	0.716	0.284	0.000
M05.1 Rheumatoid lung disease	0.716	0.284	0.000
M05.0 Felty's syndrome	0.716	0.284	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.716	0.284	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.716	0.284	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.716	0.284	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.716	0.284	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.716	0.284	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.716	0.284	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.716	0.284	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.716	0.284	0.000
E12 Malnutrition-related diabetes mellitus	0.716	0.284	0.000
E40-E46 Malnutrition	0.715	0.285	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.714	0.286	0.000
M47 Spondylosis	0.711	0.289	0.000
E11.0 With coma	0.710	0.289	0.000
M25.50 Pain in joint (Multiple sites)	0.708	0.292	0.000
M71 Other bursopathies	0.707	0.293	0.000
E11.8 With unspecified complications	0.702	0.297	0.000
E11.7 With multiple complications	0.702	0.297	0.000
E11.6 With other specified complications	0.702	0.297	0.000
M25.9 Joint disorder, unspecified	0.701	0.299	0.000
M75.0 Adhesive capsulitis of shoulder	0.698	0.302	0.000
M00-M03 Infectious arthropathies	0.698	0.302	0.000
H53-H54 Visual disturbances and blindness	0.697	0.302	0.000
M50-M54 Other dorsopathies	0.697	0.303	0.000
M25.51 Pain in joint (Shoulder region)	0.697	0.303	0.000
E11.1 With ketoacidosis	0.695	0.305	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.691	0.309	0.000
M76 Enthesopathies of lower limb, excluding foot	0.689	0.311	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.689	0.311	0.000
M25.8 Other specified joint disorders	0.687	0.313	0.000
E13 Other specified diabetes mellitus	0.687	0.313	0.000
M25.0 Haemarthrosis	0.682	0.318	0.000
E15 Nondiabetic hypoglycaemic coma	0.682	0.318	0.000
M40-M43 Deforming dorsopathies	0.679	0.321	0.000
E00-E07 Disorders of thyroid gland	0.678	0.322	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.677	0.323	0.000
H31 Other disorders of choroid	0.676	0.324	0.000
Q60-Q64 Congenital malformations of the urinary system	0.676	0.324	0.000
M11 Other crystal arthropathies	0.675	0.325	0.000
H20 Iridocyclitis	0.675	0.325	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.673	0.327	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.673	0.327	0.000
E16.4 Abnormal secretion of gastrin	0.673	0.327	0.000
E16.3 Increased secretion of glucagon	0.673	0.327	0.000
E16.1 Other hypoglycaemia	0.673	0.327	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.673	0.327	0.000
M65-M68 Disorders of synovium and tendon	0.672	0.328	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.672	0.328	0.000
Q80-Q89 Other congenital malformations	0.670	0.330	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.668	0.331	0.000
M21 Other acquired deformities of limbs	0.666	0.334	0.000
F60-F69 Disorders of adult personality and behaviour	0.665	0.334	0.000
M30 Polyarteritis nodosa and related conditions	0.662	0.338	0.000
M75.5 Bursitis of shoulder	0.661	0.339	0.000
H55-H59 Other disorders of eye and adnexa	0.660	0.340	0.000
M75.2 Bicipital tendinitis	0.656	0.344	0.000
M79.7 Fibromyalgia	0.655	0.345	0.000
H17.9 Corneal scar and opacity, unspecified	0.655	0.345	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.653	0.346	0.000
K90 Intestinal malabsorption	0.000	0.347	0.653
M10 Gout	0.650	0.350	0.000
M79.9 Soft tissue disorder, unspecified	0.650	0.350	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.650	0.350	0.000
M79.3 Panniculitis, unspecified	0.650	0.350	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.650	0.350	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.649	0.351	0.000
M82 Osteoporosis in diseases classified elsewhere	0.649	0.351	0.000
M07.3 Other psoriatic arthropathies	0.643	0.357	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.643	0.357	0.000
F41.1 Generalised anxiety disorder	0.643	0.357	0.000
F40 Phobic anxiety disorders	0.641	0.358	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.640	0.359	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.640	0.359	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.640	0.359	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.640	0.359	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.640	0.359	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.640	0.359	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.640	0.359	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.640	0.359	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.640	0.360	0.000
M54 Dorsalgia	0.639	0.361	0.000
M35 Other systemic involvement of connective tissue	0.637	0.363	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.636	0.363	0.000
F80-F89 Disorders of psychological development	0.635	0.365	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.634	0.365	0.000
E34 Other endocrine disorders	0.635	0.365	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.634	0.366	0.000
M06.38 Rheumatoid nodule (Other)	0.634	0.366	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.634	0.366	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.634	0.366	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.634	0.366	0.000
M06.33 Rheumatoid nodule (Forearm)	0.634	0.366	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.634	0.366	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.634	0.366	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.634	0.366	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.634	0.366	0.000
Q50-Q56 Congenital malformations of genital organs	0.634	0.366	0.000
F41.8 Other specified anxiety disorders	0.630	0.370	0.000
F41.3 Other mixed anxiety disorders	0.630	0.370	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.625	0.375	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.625	0.375	0.000
F48 Other neurotic disorders	0.623	0.377	0.000
F44 Dissociative [conversion] disorders	0.623	0.377	0.000
F42 Obsessive-compulsive disorder	0.623	0.377	0.000
H16 Keratitis	0.622	0.378	0.000
M24 Other specific joint derangements	0.622	0.378	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.621	0.378	0.000
F70-F79 Mental retardation	0.621	0.378	0.000
M72.2 Plantar fascial fibromatosis	0.619	0.381	0.000
H53 Visual disturbances	0.619	0.381	0.000
M77.0 Medial epicondylitis	0.617	0.382	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.617	0.383	0.000
M77.9 Enthesopathy, unspecified	0.615	0.385	0.000
H00 Hordeolum and chalazion	0.615	0.385	0.000
M47.8 Other spondylosis	0.613	0.387	0.000
M25.53 Pain in joint (Forearm)	0.612	0.388	0.000
M84 Disorders of continuity of bone	0.612	0.388	0.000
M62 Other disorders of muscle	0.612	0.388	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.611	0.389	0.000
M87 Osteonecrosis	0.611	0.389	0.000
Chapter XXII Codes for special purposes	0.611	0.389	0.000
M79.17 Myalgia (Ankle and foot)	0.609	0.391	0.000
M79.16 Myalgia (Lower leg)	0.609	0.391	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.609	0.391	0.000
M79.14 Myalgia (Hand)	0.609	0.391	0.000
M79.13 Myalgia (Forearm)	0.609	0.391	0.000
M79.12 Myalgia (Upper arm)	0.609	0.391	0.000
M79.11 Myalgia (Shoulder region)	0.609	0.391	0.000
M77.4 Metatarsalgia	0.604	0.396	0.000
E23 Hypofunction and other disorders of pituitary gland	0.603	0.397	0.000
M85 Other disorders of bone density and structure	0.603	0.397	0.000
M75.9 Shoulder lesion, unspecified	0.601	0.399	0.000
M79.08 Rheumatism, unspecified (Other)	0.600	0.400	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.600	0.400	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.600	0.400	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.600	0.400	0.000
M79.04 Rheumatism, unspecified (Hand)	0.600	0.400	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.600	0.400	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.600	0.400	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.600	0.400	0.000
M46 Other inflammatory spondylopathies	0.600	0.400	0.000
E50-E64 Other nutritional deficiencies	0.600	0.400	0.000
M83 Adult osteomalacia	0.599	0.401	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.598	0.401	0.000
Q35-Q37 Cleft lip and cleft palate	0.598	0.401	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.598	0.401	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.598	0.402	0.000
M33 Dermatopolymyositis	0.598	0.402	0.000
M32 Systemic lupus erythematosus	0.598	0.402	0.000
H30.9 Chorioretinal inflammation, unspecified	0.594	0.406	0.000
E20 Hypoparathyroidism	0.594	0.406	0.000
M25.3 Other instability of joint	0.593	0.406	0.000
E11.5 With peripheral circulatory complications	0.592	0.407	0.000
M89 Other disorders of bone	0.592	0.408	0.000
E22 Hyperfunction of pituitary gland	0.590	0.409	0.000
M25.06 Haemarthrosis (Lower leg)	0.590	0.410	0.000
E26 Hyperaldosteronism	0.589	0.411	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.587	0.413	0.000
H00.1 Chalazion	0.586	0.414	0.000
E14.8 With unspecified complications	0.586	0.414	0.000
E14.7 With multiple complications	0.586	0.414	0.000
E14.6 With other specified complications	0.586	0.414	0.000
E14.5 With peripheral circulatory complications	0.586	0.414	0.000
E14.4 With neurological complications	0.586	0.414	0.000
E14.2 Withrenal complications	0.586	0.414	0.000
E14.1 With ketoacidosis	0.586	0.414	0.000
E14.0 With coma	0.586	0.414	0.000
M86 Osteomyelitis	0.586	0.414	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.585	0.415	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.585	0.415	0.000
H15 Disorders of sclera	0.585	0.415	0.000
M25.52 Pain in joint (Upper arm)	0.582	0.418	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.582	0.418	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.582	0.418	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.582	0.418	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.582	0.418	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.582	0.418	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.582	0.418	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.582	0.418	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.582	0.418	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.582	0.418	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.582	0.418	0.000
M25.2 Flail joint	0.582	0.418	0.000
M25.1 Fistula of joint	0.582	0.418	0.000
H01 Other inflammation of eyelid	0.581	0.419	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.579	0.421	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.579	0.421	0.000
H35 Other retinal disorders	0.576	0.424	0.000
H20.9 Iridocyclitis, unspecified	0.574	0.426	0.000
M49 Spondylopathies in diseases classified elsewhere	0.574	0.426	0.000
M79.19 Myalgia (Site unspecified)	0.574	0.426	0.000
Q00-Q07 Congenital malformations of the nervous system	0.574	0.426	0.000
Chapter XX External causes of morbidity and mortality	0.572	0.428	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.572	0.428	0.000
M25.86 Other specified joint disorders (Lower leg)	0.569	0.430	0.000
M31 Other necrotising vasculopathies	0.569	0.431	0.000
M07.6 Other enteropathic arthropathies	0.568	0.432	0.000
M07.5 Arthropathy in ulcerative colitis	0.568	0.432	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.568	0.432	0.000
M07.2 Psoriatic spondylitis	0.568	0.432	0.000
M07.1 Arthritis mutilans	0.568	0.432	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.568	0.432	0.000
H40-H42 Glaucoma	0.567	0.432	0.000
M47.86 Other spondylosis (Lumbar region)	0.567	0.433	0.000
E27 Other disorders of adrenal gland	0.566	0.434	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.565	0.435	0.000
E32 Diseases of thymus	0.565	0.435	0.000
E31 Polyglandular dysfunction	0.565	0.435	0.000
E30 Disorders of puberty, not elsewhere classified	0.565	0.435	0.000
E25 Adrenogenital disorders	0.565	0.435	0.000
Q65 Congenital deformities of hip	0.564	0.436	0.000
M54.9 Dorsalgia, unspecified	0.564	0.436	0.000
E28 Ovarian dysfunction	0.564	0.436	0.000
H21 Other disorders of iris and ciliary body	0.563	0.436	0.000
M90 Osteopathies in diseases classified elsewhere	0.563	0.437	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.561	0.439	0.000
M13 Other arthritis	0.561	0.439	0.000
M22 Disorders of patella	0.560	0.440	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.559	0.441	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.442	0.558
Q66 Congenital deformities of feet	0.558	0.442	0.000
M77.8 Other enthesopathies, not elsewhere classified	0.557	0.443	0.000
M77.5 Other enthesopathy of foot	0.557	0.443	0.000
M77.3 Calcaneal spur	0.557	0.443	0.000
M77.2 Periarthritis of wrist	0.557	0.443	0.000
E24 Cushing's syndrome	0.557	0.443	0.000
M47.9 Spondylosis, unspecified	0.557	0.443	0.000
E29 Testicular dysfunction	0.557	0.443	0.000
M34 Systemic sclerosis	0.556	0.444	0.000
M75.8 Other shoulder lesions	0.556	0.444	0.000
M94 Other disorders of cartilage	0.556	0.444	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.553	0.447	0.000
M61 Calcification and ossification of muscle	0.553	0.447	0.000
M60 Myositis	0.553	0.447	0.000
M35.3 Polymyalgia rheumatica	0.551	0.449	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.551	0.449	0.000
M21.4 Flat foot [pes planus] (acquired)	0.547	0.453	0.000
M25.58 Pain in joint (Other)	0.546	0.454	0.000
H43-H45 Disorders of vitreous body and globe	0.546	0.454	0.000
M66 Spontaneous rupture of synovium and tendon	0.544	0.456	0.000
E11.4 With neurological complications	0.543	0.457	0.000
F99-F99 Unspecified mental disorder	0.543	0.457	0.000
H53.1 Subjective visual disturbances	0.543	0.457	0.000
F45 Somatoform disorders	0.542	0.457	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.542	0.458	0.000
Q76 Congenital malformations of spine and bony thorax	0.541	0.459	0.000
E07 Other disorders of thyroid	0.541	0.459	0.000
Q61 Cystic kidney disease	0.540	0.460	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.539	0.461	0.000
Q85 Phakomatoses, not elsewhere classified	0.538	0.461	0.000
M47.2 Other spondylosis with radiculopathy	0.538	0.462	0.000
M25.54 Pain in joint (Hand)	0.536	0.464	0.000
M25.59 Pain in joint (Site unspecified)	0.535	0.465	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.534	0.466	0.000
E46 Unspecified protein-energy malnutrition	0.533	0.467	0.000
M45 Ankylosing spondylitis	0.533	0.467	0.000
M79.59 Residual foreign body in soft tissue (Site unspecified)	0.532	0.468	0.000
M79.58 Residual foreign body in soft tissue (Other)	0.532	0.468	0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.532	0.468	0.000
M79.56 Residual foreign body in soft tissue (Lower leg)	0.532	0.468	0.000
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)	0.532	0.468	0.000
M79.53 Residual foreign body in soft tissue (Forearm)	0.532	0.468	0.000
M79.52 Residual foreign body in soft tissue (Upper arm)	0.532	0.468	0.000
M79.51 Residual foreign body in soft tissue (Shoulder region)	0.532	0.468	0.000
M79.50 Residual foreign body in soft tissue (Multiple sites)	0.532	0.468	0.000
H18 Other disorders of cornea	0.531	0.469	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.531	0.469	0.000
F43 Reaction to severe stress, and adjustment disorders	0.531	0.469	0.000
M93 Other osteochondropathies	0.529	0.470	0.000
M92 Other juvenile osteochondrosis	0.529	0.470	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.529	0.470	0.000
M72.9 Fibroblastic disorder, unspecified	0.529	0.471	0.000
M72.8 Other fibroblastic disorders	0.529	0.471	0.000
M72.6 Necrotizing fasciitis	0.529	0.471	0.000
M72.5 Fasciitis, not elsewhere classified	0.529	0.471	0.000
M72.4 Pseudosarcomatous fibromatosis	0.529	0.471	0.000
M72.3 Nodular fasciitis	0.529	0.471	0.000
M72.1 Knuckle pads	0.529	0.471	0.000
S80-S89 Injuries to the knee and lower leg	0.527	0.472	0.000
M24.2 Disorder of ligament	0.525	0.475	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.525	0.475	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.524	0.476	0.000
E04 Other non-toxic goitre	0.523	0.477	0.000
F60 Specific personality disorders	0.521	0.479	0.000
M80.8 Other osteoporosis with pathological fracture	0.521	0.479	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.521	0.479	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.521	0.479	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.521	0.479	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.521	0.479	0.000
H30.8 Other chorioretinal inflammations	0.521	0.479	0.000
H30.2 Posterior cyclitis	0.521	0.479	0.000
H30.1 Disseminated chorioretinal inflammation	0.521	0.479	0.000
H30.0 Focal chorioretinal inflammation	0.521	0.479	0.000
M99 Biomechanical lesions, not elsewhere classified	0.518	0.482	0.000
H17.8 Other corneal scars and opacities	0.517	0.482	0.000
H17.1 Other central corneal opacity	0.517	0.482	0.000
H17.0 Adherent leukoma	0.517	0.482	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.517	0.483	0.000
M54.3 Sciatica	0.517	0.483	0.000
Q78 Other osteochondrodysplasias	0.515	0.484	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.515	0.484	0.000
Q75 Other congenital malformations of skull and face bones	0.515	0.484	0.000
Q74 Other congenital malformations of limb(s)	0.515	0.484	0.000
Q73 Reduction defects of unspecified limb	0.515	0.484	0.000
Q72 Reduction defects of lower limb	0.515	0.484	0.000
Q71 Reduction defects of upper limb	0.515	0.484	0.000
Q70 Syndactyly	0.515	0.484	0.000
Q69 Polydactyly	0.515	0.484	0.000
Q68 Other congenital musculoskeletal deformities	0.515	0.484	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.515	0.484	0.000
M82.1 Osteoporosis in endocrine disorders	0.515	0.485	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.514	0.485	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.514	0.485	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.514	0.485	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.514	0.485	0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.514	0.485	0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.514	0.485	0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.514	0.485	0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.514	0.485	0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.514	0.485	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.514	0.485	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.514	0.486	0.000
M06.18 Adult-onset Still's disease (Other)	0.514	0.486	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.514	0.486	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.514	0.486	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.514	0.486	0.000
M06.14 Adult-onset Still's disease (Hand)	0.514	0.486	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.514	0.486	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.514	0.486	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.514	0.486	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.514	0.486	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.514	0.486	0.000
M06.28 Rheumatoid bursitis (Other)	0.514	0.486	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.514	0.486	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.514	0.486	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.514	0.486	0.000
M06.24 Rheumatoid bursitis (Hand)	0.514	0.486	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.514	0.486	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.514	0.486	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.514	0.486	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.514	0.486	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.514	0.486	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.514	0.486	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.514	0.486	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.514	0.486	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.514	0.486	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.514	0.486	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.514	0.486	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.514	0.486	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.514	0.486	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.514	0.486	0.000
M08.9 Juvenile arthritis, unspecified	0.514	0.486	0.000
M08.8 Other juvenile arthritis	0.514	0.486	0.000
M08.4 Pauciarticular juvenile arthritis	0.514	0.486	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.514	0.486	0.000
M08.2 Juvenile arthritis with systemic onset	0.514	0.486	0.000
M08.1 Juvenile ankylosing spondylitis	0.514	0.486	0.000
M08.0 Juvenile rheumatoid arthritis	0.514	0.486	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.514	0.486	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.514	0.486	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.514	0.486	0.000
M09.0 Juvenile arthritis in psoriasis	0.514	0.486	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.514	0.486	0.000
M12.5 Traumatic arthropathy	0.514	0.486	0.000
M12.4 Intermittent hydrarthrosis	0.514	0.486	0.000
M12.3 Palindromic rheumatism	0.514	0.486	0.000
M12.2 Villonodular synovitis (pigmented)	0.514	0.486	0.000
M12.1 Kaschin-Beck disease	0.514	0.486	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.514	0.486	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.514	0.486	0.000
M14.6 Neuropathic arthropathy	0.514	0.486	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.514	0.486	0.000
M14.4 Arthropathy in amyloidosis	0.514	0.486	0.000
M14.3 Lipoid dermatoarthritis	0.514	0.486	0.000
M14.2 Diabetic arthropathy	0.514	0.486	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.514	0.486	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.514	0.486	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.514	0.486	0.000
M54.1 Radiculopathy	0.514	0.486	0.000
M05.09 Felty's syndrome (Site unspecified)	0.514	0.486	0.000
M05.08 Felty's syndrome (Other)	0.514	0.486	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.514	0.486	0.000
M05.06 Felty's syndrome (Lower leg)	0.514	0.486	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.514	0.486	0.000
M05.04 Felty's syndrome (Hand)	0.514	0.486	0.000
M05.03 Felty's syndrome (Forearm)	0.514	0.486	0.000
M05.02 Felty's syndrome (Upper arm)	0.514	0.486	0.000
M05.01 Felty's syndrome (Shoulder region)	0.514	0.486	0.000
M05.00 Felty's syndrome (Multiple sites)	0.514	0.486	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.514	0.486	0.000
M05.18 Rheumatoid lung disease (Other)	0.514	0.486	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.514	0.486	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.514	0.486	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.514	0.486	0.000
M05.14 Rheumatoid lung disease (Hand)	0.514	0.486	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.514	0.486	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.514	0.486	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.514	0.486	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.514	0.486	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.514	0.486	0.000
M05.28 Rheumatoid vasculitis (Other)	0.514	0.486	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.514	0.486	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.514	0.486	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.514	0.486	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations