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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2075580
log Bayes Factor = 83.0966
Chromosome 6   position 31,503,975  (GRCh37) Explore rs2075580 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.001 0.999
Chapter XI Diseases of the digestive system
0.000 0.001 0.999
E14.3 With ophthalmic complications
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
I25.1 Atherosclerotic heart disease
0.000 0.002 0.998
K90 Intestinal malabsorption
0.000 0.002 0.998
K90-K93 Other diseases of the digestive system
0.000 0.003 0.997
E14.9 Without complications
0.000 0.003 0.997
Chapter VIII Diseases of the ear and mastoid process
0.000 0.004 0.996
E10.1 With ketoacidosis
0.000 0.006 0.994
H36.0 Diabetic retinopathy
0.000 0.007 0.993
K70-K77 Diseases of liver
0.000 0.007 0.993
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.008 0.992
H36 Retinal disorders in diseases classified elsewhere
0.000 0.008 0.992
H30-H36 Disorders of choroid and retina
0.000 0.008 0.992
E78.0 Pure hypercholesterolaemia
0.000 0.011 0.989
G35-G37 Demyelinating diseases of the central nervous system
0.989 0.011 0.000
E10.4 With neurological complications
0.000 0.013 0.987
H35 Other retinal disorders
0.000 0.013 0.987
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.013 0.987
G37 Other demyelinating diseases of central nervous system
0.987 0.013 0.000
L40.5 Arthropathic psoriasis
0.000 0.016 0.984
H65-H75 Diseases of middle ear and mastoid
0.000 0.018 0.982
G37.9 Demyelinating disease of central nervous system, unspecified
0.982 0.018 0.000
E70-E90 Metabolic disorders
0.000 0.018 0.981
Chapter VII Diseases of the eye and adnexa
0.000 0.020 0.980
K74 Fibrosis and cirrhosis of liver
0.000 0.020 0.980
H35.8 Other specified retinal disorders
0.000 0.021 0.979
I24 Other acute ischaemic heart diseases
0.000 0.022 0.978
H60-H62 Diseases of external ear
0.000 0.026 0.974
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.031 0.969
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.037 0.963
H66 Suppurative and unspecified otitis media
0.000 0.039 0.961
I25.5 Ischaemic cardiomyopathy
0.000 0.043 0.957
H66.3 Other chronic suppurative otitis media
0.000 0.044 0.956
I22 Subsequent myocardial infarction
0.000 0.044 0.956
H71 Cholesteatoma of middle ear
0.000 0.048 0.952
L43 Lichen planus
0.000 0.048 0.952
I24.8 Other forms of acute ischaemic heart disease
0.000 0.051 0.949
I20 Angina pectoris
0.000 0.059 0.941
E16 Other disorders of pancreatic internal secretion
0.000 0.064 0.936
K74.6 Other and unspecified cirrhosis of liver
0.000 0.066 0.934
I20.9 Angina pectoris, unspecified
0.000 0.068 0.932
K50-K52 Noninfective enteritis and colitis
0.000 0.078 0.922
K52 Other non-infective gastro-enteritis and colitis
0.000 0.083 0.917
E78.8 Other disorders of lipoprotein metabolism
0.000 0.086 0.914
H60 Otitis externa
0.000 0.089 0.911
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.089 0.911
E13 Other specified diabetes mellitus
0.000 0.092 0.908
E16.2 Hypoglycaemia, unspecified
0.000 0.093 0.907
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.093 0.907
H61 Other disorders of external ear
0.000 0.094 0.906
E10.5 With peripheral circulatory complications
0.000 0.102 0.898
K74.5 Biliary cirrhosis, unspecified
0.000 0.104 0.896
K60.2 Anal fissure, unspecified
0.000 0.105 0.895
L43.9 Lichen planus, unspecified
0.000 0.110 0.890
E10.8 With unspecified complications
0.000 0.114 0.886
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.114 0.886
K60 Fissure and fistula of anal and rectal regions
0.000 0.114 0.886
I25.2 Old myocardial infarction
0.000 0.117 0.883
K55-K64 Other diseases of intestines
0.000 0.119 0.881
E78.2 Mixed hyperlipidaemia
0.000 0.120 0.880
J45 Asthma
0.000 0.124 0.876
G37.8 Other specified demyelinating diseases of central nervous system
0.876 0.124 0.000
H35.2 Other proliferative retinopathy
0.000 0.127 0.873
E10.2 With renal complications
0.000 0.128 0.872
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.140 0.860
E10.0 With coma
0.000 0.141 0.859
E11.6 With other specified complications
0.000 0.141 0.859
K75 Other inflammatory liver diseases
0.000 0.143 0.857
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.147 0.853
K76 Other diseases of liver
0.000 0.155 0.845
I11 Hypertensive heart disease
0.000 0.156 0.844
E11.0 With coma
0.000 0.157 0.843
E11.3 With ophthalmic complications
0.000 0.157 0.843
E13.9 Without complications
0.000 0.158 0.842
J40-J47 Chronic lower respiratory diseases
0.000 0.161 0.839
K58 Irritable bowel syndrome
0.000 0.165 0.835
E00-E07 Disorders of thyroid gland
0.000 0.167 0.833
Chapter X Diseases of the respiratory system
0.000 0.168 0.832
K74.3 Primary biliary cirrhosis
0.000 0.170 0.830
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.173 0.827
K73 Chronic hepatitis, not elsewhere classified
0.000 0.174 0.826
K52.1 Toxic gastro-enteritis and colitis
0.000 0.180 0.820
I15 Secondary hypertension
0.000 0.185 0.815
L50-L54 Urticaria and erythema
0.000 0.187 0.813
E11.1 With ketoacidosis
0.000 0.188 0.812
E14.8 With unspecified complications
0.000 0.189 0.811
H53-H54 Visual disturbances and blindness
0.000 0.193 0.807
H61.1 Non-infective disorders of pinna
0.000 0.194 0.806
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.195 0.805
L43.8 Other lichen planus
0.000 0.195 0.805
K83 Other diseases of biliary tract
0.000 0.196 0.804
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.197 0.803
K86 Other diseases of pancreas
0.000 0.198 0.802
E03 Other hypothyroidism
0.000 0.202 0.798
H35.0 Background retinopathy and retinal vascular changes
0.000 0.203 0.797
K83.0 Cholangitis
0.000 0.204 0.796
L40.8 Other psoriasis
0.000 0.206 0.794
L40.1 Generalised pustular psoriasis
0.000 0.209 0.791
H61.3 Acquired stenosis of external ear canal
0.000 0.209 0.791
K76.9 Liver disease, unspecified
0.000 0.210 0.790
E74 Other disorders of carbohydrate metabolism
0.000 0.216 0.784
K60.0 Acute anal fissure
0.000 0.216 0.784
H35.5 Hereditary retinal dystrophy
0.000 0.216 0.784
K75.4 Autoimmune hepatitis
0.000 0.217 0.783
E03.9 Hypothyroidism, unspecified
0.000 0.218 0.782
H60.3 Other infective otitis externa
0.000 0.219 0.781
J43 Emphysema
0.000 0.219 0.781
E10.6 With other specified complications
0.000 0.219 0.781
L42 Pityriasis rosea
0.000 0.220 0.780
E14.6 With other specified complications
0.000 0.222 0.778
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.223 0.777
I23 Certain current complications following acute myocardial infarction
0.000 0.223 0.777
H35.7 Separation of retinal layers
0.000 0.224 0.776
E11.2 With renal complications
0.000 0.235 0.765
E78.6 Lipoprotein deficiency
0.000 0.237 0.763
H74 Other disorders of middle ear and mastoid
0.000 0.241 0.759
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.243 0.757
K86.1 Other chronic pancreatitis
0.000 0.245 0.755
E16.1 Other hypoglycaemia
0.000 0.245 0.755
I25.3 Aneurysm of heart
0.000 0.246 0.754
E14.1 With ketoacidosis
0.000 0.249 0.750
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.252 0.748
H34 Retinal vascular occlusions
0.000 0.252 0.748
K72 Hepatic failure, not elsewhere classified
0.000 0.254 0.746
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.744 0.256 0.000
K90.8 Other intestinal malabsorption
0.000 0.256 0.744
H66.1 Chronic tubotympanic suppurative otitis media
0.000 0.257 0.743
I20.0 Unstable angina
0.000 0.261 0.739
L40.3 Pustulosis palmaris et plantaris
0.000 0.262 0.738
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.264 0.736
H61.2 Impacted cerumen
0.000 0.264 0.736
E11.4 With neurological complications
0.000 0.265 0.735
H61.9 Disorder of external ear, unspecified
0.000 0.266 0.734
H90-H95 Other disorders of ear
0.000 0.267 0.733
H35.6 Retinal haemorrhage
0.000 0.270 0.730
H72 Perforation of tympanic membrane
0.000 0.271 0.729
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.272 0.728
K60.5 Anorectal fistula
0.000 0.273 0.727
H31 Other disorders of choroid
0.000 0.276 0.724
H60.9 Otitis externa, unspecified
0.000 0.279 0.721
J43.9 Emphysema, unspecified
0.000 0.280 0.720
E14.4 With neurological complications
0.000 0.280 0.720
K73.9 Chronic hepatitis, unspecified
0.000 0.280 0.720
L10-L14 Bullous disorders
0.000 0.282 0.718
G36 Other acute disseminated demyelination
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.285 0.715
H66.4 Suppurative otitis media, unspecified
0.000 0.285 0.715
H43-H45 Disorders of vitreous body and globe
0.000 0.287 0.713
E85 Amyloidosis
0.000 0.287 0.713
H60.5 Acute otitis externa, non-infective
0.000 0.288 0.712
E78.5 Hyperlipidaemia, unspecified
0.000 0.288 0.712
K77 Liver disorders in diseases classified elsewhere
0.000 0.288 0.712
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.289 0.711
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.289 0.711
K71 Toxic liver disease
0.000 0.292 0.708
E14.5 With peripheral circulatory complications
0.000 0.292 0.708
H35.1 Retinopathy of prematurity
0.000 0.292 0.707
E78.3 Hyperchylomicronaemia
0.000 0.292 0.707
G37.5 Concentric sclerosis [Balo]
0.707 0.293 0.000
G37.4 Subacute necrotising myelitis
0.707 0.293 0.000
G37.2 Central pontine myelinolysis
0.707 0.293 0.000
G37.1 Central demyelination of corpus callosum
0.707 0.293 0.000
G37.0 Diffuse sclerosis
0.707 0.293 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.293 0.707
K75.8 Other specified inflammatory liver diseases
0.000 0.294 0.706
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.296 0.704
H68 Eustachian salpingitis and obstruction
0.000 0.296 0.704
H67 Otitis media in diseases classified elsewhere
0.000 0.296 0.704
H54 Blindness and low vision
0.000 0.296 0.704
E77 Disorders of glycoprotein metabolism
0.000 0.296 0.704
E76 Disorders of glycosaminoglycan metabolism
0.000 0.296 0.704
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.296 0.704
E70 Disorders of aromatic amino-acid metabolism
0.000 0.296 0.704
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.296 0.704
J46 Status asthmaticus
0.000 0.296 0.704
K74.4 Secondary biliary cirrhosis
0.000 0.297 0.702
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.297 0.702
K74.1 Hepatic sclerosis
0.000 0.297 0.702
K86.2 Cyst of pancreas
0.000 0.298 0.702
K81 Cholecystitis
0.000 0.299 0.701
H70 Mastoiditis and related conditions
0.000 0.300 0.700
H60.1 Cellulitis of external ear
0.000 0.300 0.700
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.301 0.698
I25.4 Coronary artery aneurysm
0.000 0.302 0.698
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.309 0.691
H60.4 Cholesteatoma of external ear
0.000 0.309 0.691
E88 Other metabolic disorders
0.000 0.310 0.690
E15 Nondiabetic hypoglycaemic coma
0.000 0.310 0.690
H35.4 Peripheral retinal degeneration
0.000 0.312 0.688
K60.4 Rectal fistula
0.000 0.314 0.686
K76.8 Other specified diseases of liver
0.000 0.314 0.686
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.316 0.684
L43.3 Subacute (active) lichen planus
0.000 0.317 0.682
L43.2 Lichenoid drug reaction
0.000 0.317 0.682
L43.1 Bullous lichen planus
0.000 0.317 0.682
L43.0 Hypertrophic lichen planus
0.000 0.317 0.682
H60.8 Other otitis externa
0.000 0.318 0.682
H30 Chorioretinal inflammation
0.000 0.318 0.682
H54.9 Unspecified visual impairment (binocular)
0.000 0.319 0.681
H66.0 Acute suppurative otitis media
0.000 0.320 0.680
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.320 0.680
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.322 0.678
L52 Erythema nodosum
0.000 0.323 0.677
H35.9 Retinal disorder, unspecified
0.000 0.325 0.675
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.325 0.675
K90.9 Intestinal malabsorption, unspecified
0.000 0.327 0.672
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.329 0.671
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.329 0.671
E16.4 Abnormal secretion of gastrin
0.000 0.329 0.671
E16.3 Increased secretion of glucagon
0.000 0.329 0.671
E72 Other disorders of amino-acid metabolism
0.000 0.330 0.670
J90-J94 Other diseases of pleura
0.000 0.331 0.669
J60-J70 Lung diseases due to external agents
0.000 0.332 0.668
E11.5 With peripheral circulatory complications
0.000 0.335 0.665
H90 Conductive and sensorineural hearing loss
0.000 0.340 0.660
J92 Pleural plaque
0.000 0.341 0.659
E84 Cystic fibrosis
0.000 0.341 0.659
J42 Unspecified chronic bronchitis
0.000 0.341 0.659
K81.1 Chronic cholecystitis
0.000 0.343 0.657
H60.0 Abscess of external ear
0.000 0.343 0.657
H55-H59 Other disorders of eye and adnexa
0.000 0.344 0.656
I15.1 Hypertension secondary to other renal disorders
0.000 0.344 0.656
E78.1 Pure hyperglyceridaemia
0.000 0.344 0.655
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.346 0.654
H60.2 Malignant otitis externa
0.000 0.347 0.653
E13.8 With unspecified complications
0.000 0.349 0.651
E13.7 With multiple complications
0.000 0.349 0.651
E13.6 With other specified complications
0.000 0.349 0.651
E13.5 With peripheral circulatory complications
0.000 0.349 0.651
E13.4 With neurological complications
0.000 0.349 0.651
E13.3 With ophthalmic complications
0.000 0.349 0.651
E13.2 With renal complications
0.000 0.349 0.651
E13.1 With ketoacidosis
0.000 0.349 0.651
E13.0 With coma
0.000 0.349 0.651
H73 Other disorders of tympanic membrane
0.000 0.351 0.649
J92.9 Pleural plaque without asbestos
0.000 0.353 0.647
K86.3 Pseudocyst of pancreas
0.000 0.355 0.645
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.355 0.644
H74.4 Polyp of middle ear
0.000 0.356 0.644
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.357 0.643
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.360 0.640
K74.0 Hepatic fibrosis
0.000 0.360 0.639
E05.9 Thyrotoxicosis, unspecified
0.000 0.362 0.638
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.362 0.638
L51 Erythema multiforme
0.000 0.365 0.635
L40.0 Psoriasis vulgaris
0.000 0.366 0.634
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.368 0.632
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.368 0.632
I12 Hypertensive renal disease
0.000 0.368 0.632
L50 Urticaria
0.000 0.369 0.631
J45.1 Nonallergic asthma
0.000 0.372 0.628
H34.8 Other retinal vascular occlusions
0.000 0.372 0.628
E78.4 Other hyperlipidaemia
0.000 0.374 0.626
H72.0 Central perforation of tympanic membrane
0.000 0.374 0.626
E40-E46 Malnutrition
0.000 0.376 0.624
J43.2 Centrilobular emphysema
0.000 0.380 0.620
H92 Otalgia and effusion of ear
0.000 0.380 0.620
I23.8 Other current complications following acute myocardial infarction
0.000 0.383 0.617
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.384 0.616
H90.5 Sensorineural hearing loss, unspecified
0.000 0.385 0.615
K75.2 Nonspecific reactive hepatitis
0.000 0.386 0.614
K75.1 Phlebitis of portal vein
0.000 0.386 0.614
K83.3 Fistula of bile duct
0.000 0.386 0.614
I24.1 Dressler's syndrome
0.000 0.386 0.613
H43 Disorders of vitreous body
0.000 0.389 0.611
K81.9 Cholecystitis, unspecified
0.000 0.389 0.611
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.392 0.608
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.394 0.606
I15.9 Seconday hypertension, unspecified
0.000 0.394 0.606
K55 Vascular disorders of intestine
0.000 0.394 0.606
K76.5 Hepatic veno-occlusive disease
0.000 0.394 0.605
K76.4 Peliosis hepatis
0.000 0.394 0.605
K76.3 Infarction of liver
0.000 0.394 0.605
K76.2 Central haemorrhagic necrosis of liver
0.000 0.394 0.605
J69 Pneumonitis due to solids and liquids
0.000 0.396 0.604
I15.0 Renovascular hypertension
0.000 0.396 0.604
H72.2 Other marginal perforations of tympanic membrane
0.000 0.398 0.602
K72.9 Hepatic failure, unspecified
0.000 0.398 0.602
E88.2 Lipomatosis, not elsewhere classified
0.000 0.398 0.602
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.403 0.597
E00 Congenital iodine-deficiency syndrome
0.000 0.403 0.597
H66.2 Chronic atticoantral suppurative otitis media
0.000 0.403 0.596
L13 Other bullous disorders
0.000 0.406 0.594
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.407 0.592
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.407 0.592
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.410 0.590
H47.3 Other disorders of optic disk
0.000 0.413 0.587
H54.7 Unspecified visual loss
0.000 0.415 0.585
I15.8 Other secondary hypertension
0.000 0.415 0.584
I15.2 Hypertension secondary to endocrine disorders
0.000 0.415 0.584
L54 Erythema in diseases classified elsewhere
0.000 0.417 0.583
E89.3 Postprocedural hypopituitarism
0.000 0.419 0.581
E83.1 Disorders of iron metabolism
0.579 0.420 0.000
K83.5 Biliary cyst
0.000 0.423 0.576
K83.2 Perforation of bile duct
0.000 0.423 0.576
H92.1 Otorrhoea
0.000 0.423 0.577
H72.8 Other perforations of tympanic membrane
0.000 0.424 0.576
J43.8 Other emphysema
0.000 0.425 0.575
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.425 0.574
E03.5 Myxoedema coma
0.000 0.428 0.572
E03.4 Atrophy of thyroid (acquired)
0.000 0.428 0.572
E03.3 Postinfectious hypothyroidism
0.000 0.428 0.572
E03.1 Congenital hypothyroidism without goitre
0.000 0.428 0.572
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.428 0.572
E50-E64 Other nutritional deficiencies
0.000 0.428 0.572
I22.8 Subsequent myocardial infarction of other sites
0.000 0.429 0.571
H55 Nystagmus and other irregular eye movements
0.000 0.429 0.571
K83.4 Spasm of sphincter of Oddi
0.000 0.430 0.570
K58.9 Irritable bowel syndrome without diarrhoea
0.000 0.431 0.569
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.432 0.568
E85.9 Amyloidosis, unspecified
0.000 0.433 0.567
J69.0 Pneumonitis due to food and vomit
0.000 0.437 0.563
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.438 0.562
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.438 0.562
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.438 0.562
E74.2 Disorders of galactose metabolism
0.000 0.438 0.562
E74.1 Disorders of fructose metabolism
0.000 0.438 0.562
E74.0 Glycogen storage disease
0.000 0.438 0.562
J41 Simple and mucopurulent chronic bronchitis
0.000 0.438 0.562
J43.1 Panlobular emphysema
0.000 0.440 0.560
J43.0 MacLeod's syndrome
0.000 0.440 0.560
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.443 0.557
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.443 0.557
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.443 0.557
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.443 0.557
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.443 0.557
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.443 0.557
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.443 0.557
H74.2 Discontinuity and dislocation of ear ossicles
0.000 0.443 0.557
K55.8 Other vascular disorders of intestine
0.000 0.443 0.557
K83.9 Disease of biliary tract, unspecified
0.000 0.444 0.556
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.444 0.556
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.444 0.556
R07.4 Chest pain, unspecified
0.000 0.445 0.555
J85 Abscess of lung and mediastinum
0.000 0.445 0.555
J45.8 Mixed asthma
0.000 0.446 0.554
H31.1 Choroidal degeneration
0.000 0.446 0.554
H31.0 Chorioretinal scars
0.000 0.447 0.553
J92.0 Pleural plaque with presence of asbestos
0.000 0.448 0.552
K75.0 Abscess of liver
0.000 0.448 0.551
H61.8 Other specified disorders of external ear
0.000 0.451 0.549
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.451 0.548
J86 Pyothorax
0.000 0.454 0.546
E75.5 Other lipid storage disorders
0.000 0.454 0.546
E07 Other disorders of thyroid
0.000 0.455 0.545
E73 Lactose intolerance
0.000 0.456 0.544
H34.9 Retinal vascular occlusion, unspecified
0.000 0.461 0.539
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.462 0.538
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.463 0.536
H34.0 Transient retinal artery occlusion
0.000 0.463 0.536
H47.2 Optic atrophy
0.000 0.464 0.536
K72.1 Chronic hepatic failure
0.000 0.465 0.535
I12.9 Hypertensive renal disease without renal failure
0.000 0.468 0.532
K76.7 Hepatorenal syndrome
0.000 0.469 0.531
H53 Visual disturbances
0.000 0.469 0.531
H54.0 Blindness, both eyes
0.000 0.469 0.531
K75.9 Inflammatory liver disease, unspecified
0.000 0.471 0.529
E83 Disorders of mineral metabolism
0.499 0.471 0.029
E05.5 Thyroid crisis or storm
0.000 0.472 0.528
E05.4 Thyrotoxicosis factitia
0.000 0.472 0.528
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.472 0.528
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.472 0.528
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.473 0.527
E88.3 Tumour lysis syndrome
0.000 0.473 0.527
H94 Other disorders of ear in diseases classified elsewhere
0.000 0.475 0.525
H70.1 Chronic mastoiditis
0.000 0.475 0.525
H90.2 Conductive hearing loss, unspecified
0.000 0.476 0.524
H73.9 Disorder of tympanic membrane, unspecified
0.000 0.476 0.524
K76.1 Chronic passive congestion of liver
0.000 0.477 0.523
G36.0 Neuromyelitis optica [Devic]
0.522 0.478 0.000
E75.6 Lipid storage disorder, unspecified
0.000 0.478 0.522
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.478 0.522
E75.3 Sphingolipidosis, unspecified
0.000 0.478 0.522
E75.2 Other sphingolipidosis
0.000 0.478 0.522
E75.1 Other gangliosidosis
0.000 0.478 0.522
E75.0 GM2 gangliosidosis
0.000 0.478 0.522
E65-E68 Obesity and other hyperalimentation
0.000 0.480 0.520
H31.9 Disorder of choroid, unspecified
0.000 0.480 0.519
H31.4 Choroidal detachment
0.000 0.480 0.519
H31.2 Hereditary choroidal dystrophy
0.000 0.480 0.519
H43.2 Crystalline deposits in vitreous body
0.000 0.485 0.515
L10 Pemphigus
0.000 0.485 0.515
L14 Bullous disorders in diseases classified elsewhere
0.000 0.485 0.515
G36.9 Acute disseminated demyelination, unspecified
0.514 0.486 0.000
G36.8 Other specified acute disseminated demyelination
0.514 0.486 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.514 0.486 0.000
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
P90-P96 Other disorders originating in the perinatal period
0.000 0.486 0.514
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.486 0.514
P75-P78 Digestive system disorders of fetus and newborn
0.000 0.486 0.514
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.000 0.486 0.514
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.000 0.486 0.514
P35-P39 Infections specific to the perinatal period
0.000 0.486 0.514
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.000 0.486 0.514
P10-P15 Birth trauma
0.000 0.486 0.514
P05-P08 Disorders related to length of gestation and fetal growth
0.000 0.486 0.514
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.000 0.486 0.514
I02 Rheumatic chorea
0.000 0.486 0.514
I01 Rheumatic fever with heart involvement
0.000 0.486 0.514
I00 Rheumatic fever without mention of heart involvement
0.000 0.486 0.514
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.486 0.514
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.486 0.514
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.486 0.514
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.486 0.514
L41.9 Parapsoriasis, unspecified
0.000 0.486 0.513
L41.8 Other parapsoriasis
0.000 0.486 0.513
L41.5 Retiform parapsoriasis
0.000 0.486 0.513
L41.4 Large plaque parapsoriasis
0.000 0.486 0.513
L41.3 Small plaque parapsoriasis
0.000 0.486 0.513
L41.2 Lymphomatoid papulosis
0.000 0.486 0.513
L41.1 Pityriasis lichenoides chronica
0.000 0.486 0.513
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.486 0.513
L44.9 Papulosquamous disorder, unspecified
0.000 0.486 0.513
L44.8 Other specified papulosquamous disorders
0.000 0.486 0.513
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.486 0.513
L44.3 Lichen ruber moniliformis
0.000 0.486 0.513
L44.2 Lichen striatus
0.000 0.486 0.513
L44.1 Lichen nitidus
0.000 0.486 0.513
L44.0 Pityriasis rubra pilaris
0.000 0.486 0.513
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.487 0.513
K93.1 Megacolon in Chagas' disease
0.000 0.487 0.513
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.487 0.513
H31.3 Choroidal haemorrhage and rupture
0.000 0.487 0.513
E85.3 Secondary systemic amyloidosis
0.000 0.488 0.512
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.489 0.511
E85.8 Other amyloidosis
0.000 0.489 0.511
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.489 0.511
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.489 0.511
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.489 0.511
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.490 0.510
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.490 0.510
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.000 0.490 0.510
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.000 0.490 0.510
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.490 0.509
H43.9 Disorder of vitreous body, unspecified
0.000 0.492 0.508
K71.9 Toxic liver disease, unspecified
0.000 0.492 0.507
K71.8 Toxic liver disease with other disorders of liver
0.000 0.492 0.507
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.492 0.507
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.492 0.507
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.492 0.507
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.492 0.507
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.492 0.507
K71.2 Toxic liver disease with acute hepatitis
0.000 0.492 0.507
K71.0 Toxic liver disease with cholestasis
0.000 0.492 0.507
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.493 0.507
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.493 0.507
E79.1 Lesch-Nyhan syndrome
0.000 0.493 0.507
H10-H13 Disorders of conjunctiva
0.000 0.493 0.506
L13.0 Dermatitis herpetiformis
0.000 0.494 0.506
H67.8 Otitis media in other diseases classified elsewhere
0.000 0.495 0.505
H67.1 Otitis media in viral diseases classified elsewhere
0.000 0.495 0.505
H67.0 Otitis media in bacterial diseases classified elsewhere
0.000 0.495 0.505
H68.1 Obstruction of Eustachian tube
0.000 0.495 0.505

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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