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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2075650
log Bayes Factor = 139.935
Chromosome 19   position 45,395,619  (GRCh37) Explore rs2075650 on Ensembl!
Variant rs2075650 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
1.000 0.000 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
1.000 0.000 0.000
G30.9 Alzheimer's disease, unspecified
1.000 0.000 0.000
I20.9 Angina pectoris, unspecified
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
Z95.1 Presence of aortocoronary bypass graft
1.000 0.000 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
1.000 0.000 0.000
F03 Unspecified dementia
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I21 Acute myocardial infarction
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
F00-F09 Organic, including symptomatic, mental disorders
1.000 0.000 0.000
R41.0 Disorientation, unspecified
1.000 0.000 0.000
F00 Dementia in Alzheimer's disease
1.000 0.000 0.000
G30 Alzheimer's disease
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
I20.0 Unstable angina
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
1.000 0.000 0.000
G30-G32 Other degenerative diseases of the nervous system
1.000 0.000 0.000
F01.9 Vascular dementia, unspecified
1.000 0.000 0.000
I25.2 Old myocardial infarction
1.000 0.000 0.000
R29.6 Tendency to fall, not elsewhere classified
1.000 0.000 0.000
F01 Vascular dementia
1.000 0.000 0.000
Z95.5 Presence of coronary angioplasty implant and graft
1.000 0.000 0.000
E78.5 Hyperlipidaemia, unspecified
1.000 0.000 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.999 0.001 0.000
# Top node
0.999 0.001 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.999 0.001 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.998 0.002 0.000
F05.9 Delirium, unspecified
0.997 0.003 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.996 0.004 0.000
Z95.0 Presence of cardiac pacemaker
0.996 0.004 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.995 0.005 0.000
I60-I69 Cerebrovascular diseases
0.994 0.006 0.000
I21.4 Acute subendocardial myocardial infarction
0.993 0.007 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.989 0.011 0.000
I21.9 Acute myocardial infarction, unspecified
0.989 0.011 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.987 0.013 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.983 0.017 0.000
F02 Dementia in other diseases classified elsewhere
0.980 0.020 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.980 0.020 0.000
I67 Other cerebrovascular diseases
0.980 0.020 0.000
I24 Other acute ischaemic heart diseases
0.978 0.022 0.000
E78.2 Mixed hyperlipidaemia
0.974 0.026 0.000
F06.7 Mild cognitive disorder
0.971 0.029 0.000
I65.2 Occlusion and stenosis of carotid artery
0.969 0.031 0.000
I67.8 Other specified cerebrovascular diseases
0.968 0.032 0.000
R41.3 Other amnesia
0.966 0.034 0.000
E78.4 Other hyperlipidaemia
0.957 0.043 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.956 0.044 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.952 0.048 0.000
I24.8 Other forms of acute ischaemic heart disease
0.951 0.049 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.950 0.050 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.945 0.055 0.000
G30.0 Alzheimer's disease with early onset
0.935 0.065 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.924 0.076 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.919 0.081 0.000
I61 Intracerebral haemorrhage
0.919 0.081 0.000
Chapter XX External causes of morbidity and mortality
0.918 0.082 0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.912 0.088 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.910 0.090 0.000
F05.0 Delirium not superimposed on dementia, so described
0.909 0.091 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.909 0.091 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.907 0.093 0.000
I67.2 Cerebral atherosclerosis
0.906 0.094 0.000
F02.3 Dementia in Parkinson's disease
0.906 0.094 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.906 0.094 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.904 0.096 0.000
G31.8 Other specified degenerative diseases of nervous system
0.903 0.097 0.000
E85 Amyloidosis
0.903 0.097 0.000
G30.8 Other Alzheimer's disease
0.878 0.122 0.000
G40-G47 Episodic and paroxysmal disorders
0.878 0.122 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.876 0.124 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.871 0.129 0.000
R44.1 Visual hallucinations
0.868 0.132 0.000
F05.1 Delirium superimposed on dementia
0.867 0.133 0.000
E78.1 Pure hyperglyceridaemia
0.861 0.139 0.000
R45 Symptoms and signs involving emotional state
0.859 0.141 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.856 0.144 0.000
E78.8 Other disorders of lipoprotein metabolism
0.856 0.144 0.000
V40-V49 Car occupant injured in transport accident
0.853 0.147 0.000
I22 Subsequent myocardial infarction
0.852 0.148 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.850 0.150 0.000
F05.8 Other delirium
0.850 0.150 0.000
G70-G73 Diseases of myoneural junction and muscle
0.848 0.152 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.846 0.154 0.000
E80.4 Gilbert's syndrome
0.845 0.155 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.840 0.160 0.000
D60-D64 Aplastic and other anaemias
0.835 0.165 0.000
F06.2 Organic delusional [schizophrenia-like] disorder
0.832 0.168 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.830 0.170 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.829 0.171 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.824 0.176 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.823 0.177 0.000
E85.4 Organ-limited amyloidosis
0.822 0.178 0.000
D64 Other anaemias
0.814 0.186 0.000
F22 Persistent delusional disorders
0.812 0.188 0.000
E89.2 Postprocedural hypoparathyroidism
0.811 0.189 0.000
F29 Unspecified nonorganic psychosis
0.811 0.189 0.000
G44 Other headache syndromes
0.810 0.190 0.000
E50-E64 Other nutritional deficiencies
0.810 0.190 0.000
Z95.3 Presence of xenogenic heart valve
0.805 0.195 0.000
E87.6 Hypokalaemia
0.803 0.197 0.000
D64.9 Anaemia, unspecified
0.801 0.199 0.000
G20-G26 Extrapyramidal and movement disorders
0.800 0.200 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.798 0.202 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.795 0.205 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.793 0.207 0.000
R46 Symptoms and signs involving appearance and behaviour
0.790 0.210 0.000
Z95.4 Presence of other heart-valve replacement
0.788 0.212 0.000
F25 Schizoaffective disorders
0.788 0.212 0.000
R86 Abnormal findings in specimens from male genital organs
0.785 0.215 0.000
I24.1 Dressler's syndrome
0.783 0.217 0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease
0.783 0.217 0.000
G31.0 Circumscribed brain atrophy
0.782 0.218 0.000
F02.0 Dementia in Pick's disease
0.780 0.220 0.000
F23 Acute and transient psychotic disorders
0.779 0.220 0.000
R29.1 Meningismus
0.779 0.221 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.776 0.224 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.772 0.228 0.000
E74 Other disorders of carbohydrate metabolism
0.770 0.230 0.000
R27 Other lack of coordination
0.770 0.230 0.000
X20-X29 Contact with venomous animals and plants
0.769 0.231 0.000
I20.8 Other forms of angina pectoris
0.768 0.232 0.000
E89.4 Postprocedural ovarian failure
0.767 0.233 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.766 0.234 0.000
Y52 Agents primarily affecting the cardiovascular system
0.760 0.240 0.000
R45.6 Physical violence
0.758 0.242 0.000
G41 Status epilepticus
0.758 0.242 0.000
I68.0 Cerebral amyloid angiopathy
0.757 0.243 0.000
V01-V09 Pedestrian injured in transport accident
0.750 0.250 0.000
I05-I09 Chronic rheumatic heart diseases
0.742 0.258 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.740 0.259 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.738 0.262 0.000
I25.3 Aneurysm of heart
0.732 0.268 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.731 0.269 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.730 0.270 0.000
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident
0.729 0.271 0.000
G44.2 Tension-type headache
0.728 0.272 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.727 0.273 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.725 0.275 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.724 0.276 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.722 0.278 0.000
E87.0 Hyperosmolality and hypernatraemia
0.722 0.278 0.000
Y44 Agents primarily affecting blood constituents
0.721 0.279 0.000
E78.3 Hyperchylomicronaemia
0.717 0.283 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.717 0.283 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
R41.1 Anterograde amnesia
0.717 0.283 0.000
F09 Unspecified organic or symptomatic mental disorder
0.717 0.283 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.717 0.283 0.000
G30.1 Alzheimer's disease with late onset
0.717 0.283 0.000
F01.8 Other vascular dementia
0.717 0.283 0.000
F01.3 Mixed cortical and subcortical vascular dementia
0.717 0.283 0.000
F01.2 Subcortical vascular dementia
0.717 0.283 0.000
F01.1 Multi-infarct dementia
0.717 0.283 0.000
F01.0 Vascular dementia of acute onset
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.283 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
R29.4 Clicking hip
0.716 0.284 0.000
R29.3 Abnormal posture
0.716 0.284 0.000
R29.2 Abnormal reflex
0.716 0.284 0.000
R29.0 Tetany
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
R44.2 Other hallucinations
0.714 0.285 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.713 0.287 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.713 0.287 0.000
R45.5 Hostility
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
E78.6 Lipoprotein deficiency
0.710 0.290 0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease
0.709 0.291 0.000
F06.6 Organic emotionally labile [asthenic] disorder
0.709 0.291 0.000
F06.5 Organic dissociative disorder
0.709 0.291 0.000
F06.4 Organic anxiety disorder
0.709 0.291 0.000
F06.3 Organic mood [affective] disorders
0.709 0.291 0.000
F06.1 Organic catatonic disorder
0.709 0.291 0.000
F06.0 Organic hallucinosis
0.709 0.291 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.708 0.292 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.707 0.292 0.000
G45.4 Transient global amnesia
0.705 0.295 0.000
G25 Other extrapyramidal and movement disorders
0.705 0.295 0.000
I23 Certain current complications following acute myocardial infarction
0.703 0.297 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.703 0.297 0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease
0.702 0.297 0.000
F02.2 Dementia in Huntington's disease
0.702 0.297 0.000
F02.1 Dementia in Creutzfeldt-Jakob disease
0.702 0.297 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.702 0.297 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.702 0.297 0.000
I65.1 Occlusion and stenosis of basilar artery
0.702 0.297 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.702 0.297 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.702 0.297 0.000
I67.5 Moyamoya disease
0.702 0.297 0.000
I67.4 Hypertensive encephalopathy
0.702 0.297 0.000
I67.3 Progressive vascular leukoencephalopathy
0.702 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.702 0.298 0.000
Y00-Y09 Assault
0.702 0.298 0.000
R83 Abnormal findings in cerebrospinal fluid
0.702 0.298 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.701 0.299 0.000
V95-V97 Air and space transport accidents
0.697 0.303 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.697 0.303 0.000
F22.9 Persistent delusional disorder, unspecified
0.694 0.306 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.689 0.311 0.000
R26 Abnormalities of gait and mobility
0.686 0.314 0.000
F99-F99 Unspecified mental disorder
0.684 0.316 0.000
X10-X19 Contact with heat and hot substances
0.683 0.317 0.000
F28 Other nonorganic psychotic disorders
0.682 0.318 0.000
F24 Induced delusional disorder
0.682 0.318 0.000
F21 Schizotypal disorder
0.682 0.318 0.000
G45.0 Vertebro-basilar artery syndrome
0.681 0.319 0.000
F80-F89 Disorders of psychological development
0.681 0.319 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.680 0.320 0.000
E51 Thiamine deficiency
0.680 0.320 0.000
F60-F69 Disorders of adult personality and behaviour
0.680 0.320 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.679 0.320 0.000
F70-F79 Mental retardation
0.679 0.321 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.679 0.321 0.000
G70 Myasthenia gravis and other myoneural disorders
0.676 0.324 0.000
I61.8 Other intracerebral haemorrhage
0.675 0.325 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.674 0.326 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.674 0.326 0.000
G72 Other myopathies
0.673 0.327 0.000
G44.0 Cluster headache syndrome
0.673 0.327 0.000
V49.9 Car occupant [any] injured in unspecified traffic accident
0.672 0.328 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.671 0.329 0.000
E85.3 Secondary systemic amyloidosis
0.667 0.333 0.000
E85.9 Amyloidosis, unspecified
0.667 0.333 0.000
E87.3 Alkalosis
0.666 0.334 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.665 0.335 0.000
Y48 Anaesthetics and therapeutic gases
0.664 0.336 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.663 0.337 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.663 0.337 0.000
E89.5 Postprocedural testicular hypofunction
0.663 0.337 0.000
E89.1 Postprocedural hypoinsulinaemia
0.663 0.337 0.000
X23 Contact with hornets, wasps and bees
0.662 0.338 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.661 0.339 0.000
G41.0 Grand mal status epilepticus
0.661 0.339 0.000
G31.2 Degeneration of nervous system due to alcohol
0.661 0.339 0.000
E87.4 Mixed disorder of acid-base balance
0.659 0.341 0.000
Y35-Y36 Legal intervention and operations of war
0.658 0.342 0.000
X85-X99 Assault
0.658 0.342 0.000
X30-X39 Exposure to forces of nature
0.658 0.342 0.000
W65-W74 Accidental drowning and submersion
0.658 0.342 0.000
V90-V94 Water transport accidents
0.658 0.342 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.658 0.342 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.658 0.342 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.658 0.342 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.656 0.344 0.000
I25.4 Coronary artery aneurysm
0.656 0.344 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.656 0.344 0.000
V70-V79 Bus occupant injured in transport accident
0.655 0.345 0.000
E80.6 Other disorders of bilirubin metabolism
0.653 0.346 0.000
R45.4 Irritability and anger
0.653 0.347 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.652 0.348 0.000
E80.5 Crigler-Najjar syndrome
0.652 0.348 0.000
E80.3 Defects of catalase and peroxydase
0.652 0.348 0.000
E80.2 Other porphyria
0.652 0.348 0.000
E80.1 Porphyria cutanea tarda
0.652 0.348 0.000
E80.0 Hereditary erythropoietic porphyria
0.652 0.348 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.652 0.348 0.000
W20-W49 Exposure to inanimate mechanical forces
0.651 0.349 0.000
Y54.4 Loop [high-ceiling] diuretics
0.649 0.351 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.649 0.351 0.000
E85.8 Other amyloidosis
0.647 0.352 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.647 0.352 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.647 0.352 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.647 0.352 0.000
X50-X57 Overexertion, travel and privation
0.647 0.353 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.646 0.354 0.000
G44.1 Vascular headache, not elsewhere classified
0.644 0.356 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.643 0.356 0.000
E61 Deficiency of other nutrient elements
0.643 0.357 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.643 0.357 0.000
D50-D53 Nutritional anaemias
0.643 0.357 0.000
W50-W64 Exposure to animate mechanical forces
0.642 0.357 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.640 0.360 0.000
G71 Primary disorders of muscles
0.640 0.360 0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions
0.639 0.361 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.638 0.362 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.637 0.362 0.000
Y43 Primarily systemic agents
0.637 0.363 0.000
F25.1 Schizoaffective disorder, depressive type
0.634 0.366 0.000
E89.3 Postprocedural hypopituitarism
0.634 0.366 0.000
Y71 Cardiovascular devices associated with adverse incidents
0.633 0.367 0.000
R86.8 Other abnormal findings
0.632 0.368 0.000
I08 Multiple valve diseases
0.632 0.368 0.000
R86.0 Abnormal level of enzymes
0.631 0.369 0.000
R87 Abnormal findings in specimens from female genital organs
0.631 0.369 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.631 0.369 0.000
F20 Schizophrenia
0.629 0.371 0.000
D61 Other aplastic anaemias
0.627 0.373 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.627 0.373 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.627 0.373 0.000
I25.5 Ischaemic cardiomyopathy
0.626 0.374 0.000
Y59 Other and unspecified vaccines and biological substances
0.625 0.375 0.000
Y58 Bacterial vaccines
0.625 0.375 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.625 0.375 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.625 0.375 0.000
V98-V99 Other and unspecified transport accidents
0.624 0.376 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.624 0.376 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.623 0.377 0.000
F25.2 Schizoaffective disorder, mixed type
0.620 0.379 0.000
Y54.8 Agents affecting uric acid metabolism
0.618 0.382 0.000
R27.8 Other and unspecified lack of coordination
0.618 0.382 0.000
F22.0 Delusional disorder
0.618 0.382 0.000
I06 Rheumatic aortic valve diseases
0.617 0.382 0.000
G10 Huntington's disease
0.617 0.383 0.000
R45.7 State of emotional shock and stress, unspecified
0.616 0.384 0.000
R45.3 Demoralisation and apathy
0.616 0.384 0.000
X45 Accidental poisoning by and exposure to alcohol
0.615 0.385 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.614 0.386 0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.614 0.386 0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.614 0.386 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.612 0.387 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.612 0.388 0.000
V47 Car occupant injured in collision with fixed or stationary object
0.612 0.388 0.000
V46 Car occupant injured in collision with other nonmotor vehicle
0.612 0.388 0.000
V45 Car occupant injured in collision with railway train or railway vehicle
0.612 0.388 0.000
V42 Car occupant injured in collision with two- or three-wheeled motor vehicle
0.612 0.388 0.000
V41 Car occupant injured in collision with pedal cycle
0.612 0.388 0.000
V40 Car occupant injured in collision with pedestrian or animal
0.612 0.388 0.000
Y44.5 Thrombolytic drugs
0.611 0.389 0.000
R45.0 Nervousness
0.610 0.390 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.610 0.390 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.610 0.390 0.000
D62 Acute posthaemorrhagic anaemia
0.608 0.392 0.000
R46.4 Slowness and poor responsiveness
0.608 0.392 0.000
Y40 Systemic antibiotics
0.608 0.392 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.608 0.392 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.606 0.394 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.605 0.395 0.000
V10-V19 Pedal cyclist injured in transport accident
0.605 0.395 0.000
R45.1 Restlessness and agitation
0.605 0.395 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.605 0.395 0.000
G11 Hereditary ataxia
0.602 0.398 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.602 0.398 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.601 0.398 0.000
D50 Iron deficiency anaemia
0.601 0.399 0.000
R86.9 Unspecified abnormal finding
0.600 0.400 0.000
G24 Dystonia
0.600 0.400 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.599 0.401 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.599 0.401 0.000
G14 Postpolio syndrome
0.598 0.401 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.598 0.402 0.000
R84.5 Abnormal microbiological findings
0.597 0.403 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.596 0.404 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.595 0.405 0.000
Y52.1 Calcium-channel blockers
0.594 0.406 0.000
R43 Disturbances of smell and taste
0.594 0.406 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.592 0.407 0.000
E73 Lactose intolerance
0.591 0.408 0.000
Y77 Ophthalmic devices associated with adverse incidents
0.591 0.409 0.000
R46.2 Strange and inexplicable behaviour
0.589 0.411 0.000
I20.1 Angina pectoris with documented spasm
0.588 0.411 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.588 0.412 0.000
E51.2 Wernicke's encephalopathy
0.587 0.413 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.587 0.413 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.587 0.413 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.586 0.414 0.000
R46.8 Other symptoms and signs involving appearance and behaviour
0.585 0.415 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.585 0.415 0.000
D64.4 Congenital dyserythropoietic anaemia
0.583 0.416 0.000
D64.3 Other sideroblastic anaemias
0.583 0.416 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.583 0.416 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.583 0.416 0.000
D64.0 Hereditary sideroblastic anaemia
0.583 0.416 0.000
V48 Car occupant injured in noncollision transport accident
0.583 0.417 0.000
F22.8 Other persistent delusional disorders
0.582 0.418 0.000
V04 Pedestrian injured in collision with heavy transport vehicle or bus
0.582 0.418 0.000
G44.3 Chronic posttraumatic headache
0.581 0.419 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.580 0.419 0.000
E63 Other nutritional deficiencies
0.580 0.419 0.000
E56 Other vitamin deficiencies
0.580 0.419 0.000
E50 Vitamin A deficiency
0.580 0.419 0.000
E60 Dietary zinc deficiency
0.580 0.419 0.000
E59 Dietary selenium deficiency
0.580 0.419 0.000
E58 Dietary calcium deficiency
0.580 0.419 0.000
E54 Ascorbic acid deficiency
0.580 0.419 0.000
E52 Niacin deficiency [pellagra]
0.580 0.419 0.000
Y54.3 Benzothiadiazine derivatives
0.580 0.420 0.000
D63.0 Anaemia in neoplastic disease
0.578 0.422 0.000
V80-V89 Other land transport accidents
0.577 0.422 0.000
F25.9 Schizoaffective disorder, unspecified
0.577 0.423 0.000
V20-V29 Motorcycle rider injured in transport accident
0.577 0.423 0.000
I08.0 Disorders of both mitral and aortic valves
0.575 0.425 0.000
I62 Other nontraumatic intracranial haemorrhage
0.575 0.425 0.000
G23 Other degenerative diseases of basal ganglia
0.573 0.427 0.000
G21 Secondary Parkinsonism
0.573 0.427 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.573 0.427 0.000
G22 Parkinsonism in diseases classified elsewhere
0.573 0.427 0.000
V49.8 Car occupant [any] injured in other specified transport accidents
0.572 0.428 0.000
V49.6 Unspecified car occupant injured in collision with other and unspecified motor vehicles in traffic accident
0.572 0.428 0.000
V49.3 Car occupant [any] injured in unspecified nontraffic accident
0.572 0.428 0.000
V49.2 Unspecified car occupant injured in collision with other and unspecified motor vehicles in nontraffic accident
0.572 0.428 0.000
V49.1 Passenger injured in collision with other and unspecified motor vehicles in nontraffic accident
0.572 0.428 0.000
V49.0 Driver injured in collision with other and unspecified motor vehicles in nontraffic accident
0.572 0.428 0.000
E53 Deficiency of other B group vitamins
0.571 0.429 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.570 0.430 0.000
V09 Pedestrian injured in other and unspecified transport accidents
0.570 0.430 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.569 0.431 0.000
Y28 Contact with sharp object, undetermined intent
0.569 0.431 0.000
Y04 Assault by bodily force
0.568 0.431 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.567 0.432 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.567 0.433 0.000
R46.7 Verbosity and circumstantial detail obscuring reason for contact
0.566 0.433 0.000
R46.6 Undue concern and preoccupation with stressful events
0.566 0.433 0.000
R46.5 Suspiciousness and marked evasiveness
0.566 0.433 0.000
R46.3 Overactivity
0.566 0.433 0.000
R46.1 Bizarre personal appearance
0.566 0.433 0.000
R46.0 Very low level of personal hygiene
0.566 0.433 0.000
G41.9 Status epilepticus, unspecified
0.566 0.434 0.000
V01 Pedestrian injured in collision with pedal cycle
0.566 0.434 0.000
V49.5 Passenger injured in collision with other and unspecified motor vehicles in traffic accident
0.565 0.435 0.000
F25.8 Other schizoaffective disorders
0.565 0.435 0.000
D50.8 Other iron deficiency anaemias
0.565 0.435 0.000
I08.8 Other multiple valve diseases
0.565 0.435 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.564 0.436 0.000
R86.7 Abnormal histological findings
0.563 0.437 0.000
R86.6 Abnormal cytological findings
0.563 0.437 0.000
R86.5 Abnormal microbiological findings
0.563 0.437 0.000
R86.4 Abnormal immunological findings
0.563 0.437 0.000
R86.3 Abnormal level of substances chiefly nonmedicinal as to source
0.563 0.437 0.000
R86.2 Abnormal level of other drugs, medicaments and biological substances
0.563 0.437 0.000
R86.1 Abnormal level of hormones
0.563 0.437 0.000
R45.8 Other symptoms and signs involving emotional state
0.562 0.438 0.000
R41.2 Retrograde amnesia
0.562 0.438 0.000
R44.0 Auditory hallucinations
0.562 0.438 0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents
0.562 0.438 0.000
G25.0 Essential tremor
0.561 0.439 0.000
G70.0 Myasthenia gravis
0.561 0.439 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.560 0.440 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.560 0.440 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.559 0.441 0.000
F23.8 Other acute and transient psychotic disorders
0.559 0.441 0.000
F23.3 Other acute predominantly delusional psychotic disorders
0.559 0.441 0.000
F23.2 Acute schizophrenia-like psychotic disorder
0.559 0.441 0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia
0.559 0.441 0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.559 0.441 0.000
Y43.3 Other antineoplastic drugs
0.557 0.443 0.000
Y82 Other and unspecified medical devices associated with adverse incidents
0.556 0.444 0.000
Y81 General- and plastic-surgery devices associated with adverse incidents
0.556 0.444 0.000
Y80 Physical medicine devices associated with adverse incidents
0.556 0.444 0.000
Y78 Radiological devices associated with adverse incidents
0.556 0.444 0.000
Y75 Neurological devices associated with adverse incidents
0.556 0.444 0.000
Y74 General hospital and personal-use devices associated with adverse incidents
0.556 0.444 0.000
Y72 Otorhinolaryngological devices associated with adverse incidents
0.556 0.444 0.000
Y70 Anaesthesiology devices associated with adverse incidents
0.556 0.444 0.000
D55-D59 Haemolytic anaemias
0.555 0.445 0.000
I09 Other rheumatic heart diseases
0.555 0.445 0.000
F07.2 Postconcussional syndrome
0.554 0.445 0.000
Y54.9 Mineral salts, not elsewhere classified
0.554 0.446 0.000
Y54.7 Agents affecting calcification
0.554 0.446 0.000
Y54.6 Electrolytic, caloric and water-balance agents
0.554 0.446 0.000
Y54.2 Carbonic-anhydrase inhibitors
0.554 0.446 0.000
Y54.0 Mineralocorticoids
0.554 0.446 0.000
R83.8 Other abnormal findings
0.553 0.447 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.552 0.448 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.552 0.448 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.552 0.448 0.000
E74.2 Disorders of galactose metabolism
0.552 0.448 0.000
E74.1 Disorders of fructose metabolism
0.552 0.448 0.000
E74.0 Glycogen storage disease
0.552 0.448 0.000
X23.9 Unspecified place
0.552 0.448 0.000
X29 Contact with unspecified venomous animal or plant
0.551 0.448 0.000
X28 Contact with other specified venomous plants
0.551 0.448 0.000
X27 Contact with other specified venomous animals
0.551 0.448 0.000
X26 Contact with venomous marine animals and plants
0.551 0.448 0.000
X25 Contact with other specified venomous arthropods
0.551 0.448 0.000
X24 Contact with centipedes and venomous millipedes (tropical)
0.551 0.448 0.000
X22 Contact with scorpions
0.551 0.448 0.000
X21 Contact with venomous spiders
0.551 0.448 0.000
X20 Contact with venomous snakes and lizards
0.551 0.448 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.551 0.449 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.550 0.450 0.000
Y48.3 Local anaesthetics
0.550 0.450 0.000
F25.0 Schizoaffective disorder, manic type
0.548 0.452 0.000
X09 Exposure to unspecified smoke, fire and flames
0.547 0.452 0.000
E20-E35 Disorders of other endocrine glands
0.547 0.453 0.000
G12 Spinal muscular atrophy and related syndromes
0.547 0.453 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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